assisted reproductive techniques

Summary

Summary: Clinical and laboratory techniques used to enhance fertility in humans and animals.

Top Publications

  1. ncbi Economic implications of assisted reproductive techniques: a systematic review
    L Garceau
    Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK
    Hum Reprod 17:3090-109. 2002
  2. ncbi Cost--effectiveness analysis of salpingectomy prior to IVF, based on a randomized controlled trial
    Annika Strandell
    Reproductive Medicine, Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Goteborg, Sweden
    Hum Reprod 20:3284-92. 2005
  3. ncbi Oxidative stress in an assisted reproductive techniques setting
    Ashok Agarwal
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute and Department of Obstetrics Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Fertil Steril 86:503-12. 2006
  4. pmc Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies
    Frans M Helmerhorst
    Department of Obstetrics, Gynaecology and Reproductive Medicine, Leiden University Medical Center, NL 2300 Leiden, Netherlands
    BMJ 328:261. 2004
  5. ncbi Twenty years experience with semen cryopreservation in testicular cancer patients: who needs it?
    H Magelssen
    The Norwegian Radium Hospital, Dep of Clinical Research, Montebello, 0310 Oslo, Norway
    Eur Urol 48:779-85. 2005
  6. ncbi The effect of cancer treatment on female fertility and strategies for preserving fertility
    Theodoros Maltaris
    Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany
    Eur J Obstet Gynecol Reprod Biol 130:148-55. 2007
  7. ncbi Introduction of various vietnamese indigenous pig breeds and their conservation by using assisted reproductive techniques
    Thanh Quang Dang-Nguyen
    Department of Animal Breeding and Reproduction, National Institute of Livestock and Grassland Science, Japan
    J Reprod Dev 56:31-5. 2010
  8. ncbi Late, but not early, paternal effect on human embryo development is related to sperm DNA fragmentation
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Hum Reprod 19:611-5. 2004
  9. ncbi Safety and efficacy of sperm washing in HIV-1-serodiscordant couples where the male is infected: results from the European CREAThE network
    Louis Bujan
    University Toulouse III Paul Sabatier, EA 3694, Research Group on Human Fertility, Toulouse, France
    AIDS 21:1909-14. 2007
  10. pmc Imprinting disorders and assisted reproductive technology
    Somjate Manipalviratn
    Reproductive Biology and Medicine Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Fertil Steril 91:305-15. 2009

Detail Information

Publications247 found, 100 shown here

  1. ncbi Economic implications of assisted reproductive techniques: a systematic review
    L Garceau
    Department of Obstetrics and Gynaecology, University of Oxford, Oxford, UK
    Hum Reprod 17:3090-109. 2002
    ..The economic implications of the use of assisted reproductive techniques require consideration. Herein, the health economics research in this area are critically appraised.
  2. ncbi Cost--effectiveness analysis of salpingectomy prior to IVF, based on a randomized controlled trial
    Annika Strandell
    Reproductive Medicine, Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Goteborg, Sweden
    Hum Reprod 20:3284-92. 2005
    ..This study compared the cost-effectiveness of this strategy (intervention) with that of optional salpingectomy after a failed cycle (control)...
  3. ncbi Oxidative stress in an assisted reproductive techniques setting
    Ashok Agarwal
    Center for Advanced Research in Human Reproduction, Infertility and Sexual Function, Glickman Urological Institute and Department of Obstetrics Gynecology, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Fertil Steril 86:503-12. 2006
    The manipulation of gametes and embryos in an in vitro environment when performing assisted reproductive techniques (ART) carries the risk of exposure of these cells to supraphysiological levels of reactive oxygen species (ROS)...
  4. pmc Perinatal outcome of singletons and twins after assisted conception: a systematic review of controlled studies
    Frans M Helmerhorst
    Department of Obstetrics, Gynaecology and Reproductive Medicine, Leiden University Medical Center, NL 2300 Leiden, Netherlands
    BMJ 328:261. 2004
    ..To compare the perinatal outcome of singleton and twin pregnancies between natural and assisted conceptions...
  5. ncbi Twenty years experience with semen cryopreservation in testicular cancer patients: who needs it?
    H Magelssen
    The Norwegian Radium Hospital, Dep of Clinical Research, Montebello, 0310 Oslo, Norway
    Eur Urol 48:779-85. 2005
    ..To evaluate the role of semen cryopreservation (SCP) in the fertility saving management of testicular cancer (TC) patients, treated at the Norwegian Radium Hospital between 1983 and 2002...
  6. ncbi The effect of cancer treatment on female fertility and strategies for preserving fertility
    Theodoros Maltaris
    Department of Obstetrics and Gynecology, Johannes Gutenberg University, Mainz, Germany
    Eur J Obstet Gynecol Reprod Biol 130:148-55. 2007
    ....
  7. ncbi Introduction of various vietnamese indigenous pig breeds and their conservation by using assisted reproductive techniques
    Thanh Quang Dang-Nguyen
    Department of Animal Breeding and Reproduction, National Institute of Livestock and Grassland Science, Japan
    J Reprod Dev 56:31-5. 2010
    ..Moreover, recent genetic research has shown that Vietnamese pigs are genetically diverse. Thus, conservation of these pig breeds using assisted reproductive techniques is urgent and important.
  8. ncbi Late, but not early, paternal effect on human embryo development is related to sperm DNA fragmentation
    Jan Tesarik
    MAR and Gen, Molecular Assisted Reproduction and Genetics, Gracia 36, 18002 Granada, Spain
    Hum Reprod 19:611-5. 2004
    ..It is known that repeated failure of assisted reproduction treatment (ART) can be due to a paternal effect. This study was undertaken to analyse the possible relationship between ART failure and sperm DNA fragmentation...
  9. ncbi Safety and efficacy of sperm washing in HIV-1-serodiscordant couples where the male is infected: results from the European CREAThE network
    Louis Bujan
    University Toulouse III Paul Sabatier, EA 3694, Research Group on Human Fertility, Toulouse, France
    AIDS 21:1909-14. 2007
    ..To examine the safety and effectiveness of assisted reproduction using sperm washing for HIV-1-serodiscordant couples wishing to procreate where the male partner is infected...
  10. pmc Imprinting disorders and assisted reproductive technology
    Somjate Manipalviratn
    Reproductive Biology and Medicine Branch, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20892, USA
    Fertil Steril 91:305-15. 2009
    ..To review currently available literature on the association between imprinting disorders (Beckwith-Wiedemann syndrome [BWS], Angelman syndrome [AS] and retinoblastoma) and assisted reproductive technology (ART) in humans...
  11. ncbi Potential importance of vitrification in reproductive medicine
    Juergen Liebermann
    Shady Grove Fertility Reproductive Science Center, Rockville, Maryland 20850, USA
    Biol Reprod 67:1671-80. 2002
    ..Clearly, however, attention needs to be paid to the inconsistent survival rates following vitrification...
  12. ncbi Risk of cranial ultrasound abnormalities in very-low-birth-weight infants conceived with assisted reproductive techniques
    Jane E Stewart
    Beth Israel Deaconess Medical Center, Boston, MA 02115, USA
    J Perinatol 22:37-45. 2002
    ..risks of cranial ultrasound abnormalities among very-low-birth-weight (VLBW) infants conceived with fertility therapy (ovulation induction only or with assisted reproductive techniques [ART]) and of multiple gestation pregnancies.
  13. ncbi Can assisted reproduction technology compensate for the natural decline in fertility with age? A model assessment
    Henri Leridon
    U569 Epidemiology, demography and social sciences IFR69, INSERM French Institute of Health and Medical Research and INED National Institute for Demographic Studies
    Hum Reprod 19:1548-53. 2004
    ..Maternal age is an important factor in reproduction. Can assisted reproduction technologies (ART) fully compensate for the decline in fertility with age?..
  14. ncbi Multiple gestation and infertility treatment: registration, reflection and reaction--the Belgian project
    Willem Ombelet
    Genk Institute for Fertility Technology, Department of Obstetrics and Gynaecology, Genk, Belgium
    Hum Reprod Update 11:3-14. 2005
    ....
  15. ncbi Individualizing FSH dose for assisted reproduction using a novel algorithm: the CONSORT study
    F Olivennes
    Reprod Biomed Online 18:195-204. 2009
    ..2%). Two patients had severe OHSS. Use of the CONSORT algorithm achieved an adequate oocyte yield and good pregnancy rates in this preliminary study. Adjustment of the algorithm could reduce cancellation rates...
  16. ncbi Predictive factors and a corresponding treatment algorithm for controlled ovarian stimulation in patients treated with recombinant human follicle stimulating hormone (follitropin alfa) during assisted reproduction technology (ART) procedures. An analysis
    C M Howles
    Serono Singapore Pte, Singapore
    Curr Med Res Opin 22:907-18. 2006
    ....
  17. ncbi Clinical and molecular genetic features of Beckwith-Wiedemann syndrome associated with assisted reproductive technologies
    Derek Lim
    Department of Medical and Molecular Genetics, University of Birmingham School of Medicine, Institute of Biomedical Research, Birmingham B15 2TT, UK
    Hum Reprod 24:741-7. 2009
    ..5 imprinting control regions (IC1 and IC2). Previously, we and other reported an association between sporadic BWS and assisted reproductive technologies (ARTs)...
  18. ncbi Aberrant DNA methylation of imprinted loci in superovulated oocytes
    A Sato
    St Luke Clinic, Tsumori, Oita, Japan
    Hum Reprod 22:26-35. 2007
    ..The most likely candidate for the gametic mark is DNA methylation. However, the timing of DNA methylation acquisition in adult oocytogenesis and the effects of superovulation are unknown...
  19. ncbi World collaborative report on in vitro fertilization, 2000
    G David Adamson
    Fertility Physicians of Northern California, Palo Alto, California 94301, USA
    Fertil Steril 85:1586-622. 2006
    ..0% per transfer. Conventional IVF and ICSI twin rates were 26.9% and 26.2%, respectively, and triplet rates were 2.8% and 2.9%, respectively, for an estimated total of approximately 197,000 to 220,000 babies worldwide...
  20. ncbi Congenital abnormalities in children born after assisted reproductive techniques: how much is associated with the presence of infertility and how much with its treatment?
    William M Buckett
    Department of Obstetrics and Gynecology, McGill University, Montreal, Quebec, Canada
    Fertil Steril 84:1318-9; discussion 1327. 2005
    ..Much evidence suggests that infertility itself might be a risk factor, and further long-term follow-up studies involving different possible control groups will help determine whether these abnormalities are directly related to treatment...
  21. ncbi Epigenetic risks related to assisted reproductive technologies: risk analysis and epigenetic inheritance
    M De Rycke
    Centre for Medical Genetics, University Hospital of the Dutch speaking Brussels Free University, Laarbeeklaan 101, Belgium
    Hum Reprod 17:2487-94. 2002
    ..The interference of in-vitro embryo culture, immature sperm cells and nuclear transfer with epigenetic reprogramming is discussed, as well as the possibility of epigenetic inheritance...
  22. ncbi Sperm banking and rate of assisted reproduction treatment: insights from a 15-year cryopreservation program for male cancer patients
    Guido Ragni
    Infertility Unit, Department Obstetrics and Gynecology, University of Milan, Milan, Italy
    Cancer 97:1624-9. 2003
    ..However, the necessity and the justification of banking spermatozoa have been questioned because it has been reported that only a small percentage of patients are referred for assisted reproductive technologies using frozen semen...
  23. ncbi Gestational surrogacy
    Peter R Brinsden
    Bourn Hall Clinic, Bourn, Cambridge CB3 7TR, UK
    Hum Reprod Update 9:483-91. 2003
    ..IVF surrogacy is therefore a successful treatment for a small group of women who would otherwise not be able to have their own genetic children...
  24. ncbi Oogenesis as a foundation for embryogenesis
    R G Gosden
    Department of Obstetrics and Gynecology, Division of Reproductive Biology, Royal Victoria Hospital, McGill University, Women s Pavilion F3 38, 687 Pine Avenue West, Quebec, H3A 1A1, Montreal, Canada
    Mol Cell Endocrinol 186:149-53. 2002
    ..On the other hand, the oocyte actively influences the growth and differentiation of its granulosa cells. Thus, healthy embryos reflect the quality of both the oocyte and the granulosa cells...
  25. ncbi Recombinant human leukemia inhibitory factor does not improve implantation and pregnancy outcomes after assisted reproductive techniques in women with recurrent unexplained implantation failure
    Peter R Brinsden
    Bourn Hall Clinic, Bourn, Cambridge, Cambridgeshire, United Kingdom
    Fertil Steril 91:1445-7. 2009
    ..study, women (n = 149) with a history of at least two unexplained implantation failures after assisted reproductive techniques received recombinant human leukemia inhibitory factor, 150 microg SC twice daily for 7 days, or ..
  26. pmc The effects of oxidative stress on outcomes of assisted reproductive techniques
    Ozay Oral
    Zeynep Kamil Training and Research Hospital, Assisted Reproductive Techniques Department, Istanbul, Turkey
    J Assist Reprod Genet 23:81-5. 2006
    ..To investigate the impact of oxidative stress on pregnancy success by monitoring malondialdehyde levels in follicular fluid...
  27. ncbi Leptin and ovarian folliculogenesis: implications for ovulation induction and ART outcomes
    John D Brannian
    Department of Obstetrics and Gynecology, University of South Dakota School of Medicine, Sioux Falls, South Dakota 57105 1570, USA
    Semin Reprod Med 20:103-12. 2002
    ..Moreover, polycystic ovarian syndrome may be associated with altered leptin phsyiology...
  28. ncbi Are children born after assisted reproductive technology at increased risk for adverse health outcomes?
    Laura A Schieve
    Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, 4770 Buford Highway NE, Atlanta, GA 30341, USA
    Obstet Gynecol 103:1154-63. 2004
    ..Future research needs to address the unique methodological challenges underlying study in this area...
  29. ncbi Gonadotropin-releasing hormone antagonists for assisted reproductive techniques: are there clinical differences between agents?
    Georg Griesinger
    Department of Obstetrics and Gynecology, Medical University of Schleswig Holstein, Campus Lubeck, Ratzeburger Allee 160, 23538 Lubeck, Germany
    Drugs 64:563-75. 2004
    ..hormone (GnRH) antagonists have been tested extensively in ovarian stimulation protocols for assisted reproductive techniques (ART)...
  30. ncbi Who should pay for assisted reproductive techniques? Answers from patients, professionals and the general public in Germany
    O Rauprich
    Institute for Medical Ethics and History of Medicine, Ruhr University Bochum, Markstr 258a, D 44799 Bochum, Germany
    Hum Reprod 25:1225-33. 2010
    ....
  31. ncbi [Impact of infertility and assisted reproductive techniques on sexuality]
    J Ohl
    Centre d Assistance médicale à la procréation AMP de Strasbourg, CMCO SIHCUS, Schiltigheim, France
    Gynecol Obstet Fertil 37:25-32. 2009
    We studied the impact of infertility and all the more Assisted Reproductive Techniques on marital relations and sexuality.
  32. ncbi GnRH analogues: applications in assisted reproductive techniques
    Catherine Hayden
    Reproductive Medicine Unit, The Leeds Teaching Hospitals NHS Trust, Clarendon Wing, Belmont Grove, Leeds LS29NS, UK
    Eur J Endocrinol 159:S17-25. 2008
    The ability to prevent an endogenous LH surge revolutionised the efficacy of assisted reproductive techniques (ART) such that GnRH agonists were rapidly adopted in the 1980s...
  33. ncbi Exogenous luteinizing hormone in controlled ovarian hyperstimulation for assisted reproduction techniques
    Anna Pia Ferraretti
    SISMER Reproductive Unit, Bologna, Italy
    Fertil Steril 82:1521-6. 2004
    ..To investigate the role of exogenous LH in controlled ovarian hyperstimulation for assisted reproductive technologies...
  34. ncbi Manipulations of mouse embryos prior to implantation result in aberrant expression of imprinted genes on day 9.5 of development
    Rocio M Rivera
    Department of Biology, University of Pennsylvania, Philadelphia, PA 19104, USA
    Hum Mol Genet 17:1-14. 2008
    ..Additionally, our results serve as a cautionary tale for gene expression studies in which embryo transfer is used...
  35. ncbi Infertility, assisted reproductive technology, and adverse pregnancy outcomes: executive summary of a National Institute of Child Health and Human Development workshop
    Uma M Reddy
    Pregnancy and Perinatology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 7510, USA
    Obstet Gynecol 109:967-77. 2007
    ..Significant gaps in knowledge were identified, and the basic science and clinical and epidemiologic research required to address these gaps is outlined...
  36. pmc Mouse embryo culture induces changes in postnatal phenotype including raised systolic blood pressure
    Adam J Watkins
    School of Biological Sciences, University of Southampton, Bassett Crescent East, Southampton SO16 7PX, UK
    Proc Natl Acad Sci U S A 104:5449-54. 2007
    ..These animal data indicate that postnatal physiological criteria important in cardiovascular and metabolic health may be more sensitive to routine ART procedures than growth...
  37. ncbi Using the alkaline comet assay in prognostic tests for male infertility and assisted reproductive technology outcomes
    Sheena E M Lewis
    Reproductive Medicine, Queen s University of Belfast, Institute of Clinical Science, Grosvenor Road, Belfast, BT12 6BJ, Northern Ireland, UK
    Mutagenesis 23:163-70. 2008
    ..Finally, the usefulness of sperm DNA tests as prognostic markers and in particular, the opportunities and challenges provided by DNA testing in male fertility determination will be discussed...
  38. ncbi Detection of HIV-1 RNA in seminal plasma samples from treated patients with undetectable HIV-1 RNA in blood plasma
    Anne Genevieve Marcelin
    UPMC Univ Paris 06, EA 2387, Paris, France
    AIDS 22:1677-9. 2008
    ..This result justifies measuring HIV-1 RNA in semen before the ART process and suggests that a residual risk of transmission has to be mentioned to the patients who would like to have unprotected sexual intercourse...
  39. ncbi Incidence of spontaneous abortion among pregnancies produced by assisted reproductive technology
    Jim X Wang
    Reproductive Medicine Unit, Department of Obstetrics and Gynaecology, University of Adelaide, The Queen Elizabeth Hospital, Woodville, SA, Australia 5011
    Hum Reprod 19:272-7. 2004
    ....
  40. ncbi Exploiting LH in ovarian stimulation
    C Alviggi
    Dipartimento di Scienze Ostetriche Ginecologiche Urologiche e Medicina della Riproduzione Università degli Studi di Napoli Federico II, Via S Pansini 5, 80131, Naples, Italy
    Reprod Biomed Online 12:221-33. 2006
    ....
  41. ncbi Potential significance of genomic imprinting defects for reproduction and assisted reproductive technology
    Diana Lucifero
    McGill University Montreal Children s Hospital Research Institute and Department of Paediatrics, McGill University, Montreal, Quebec, H3H 1P3, Canada
    Hum Reprod Update 10:3-18. 2004
    ....
  42. ncbi Management of endometriomas in women requiring IVF: to touch or not to touch
    Juan A Garcia-Velasco
    IVI Madrid, Rey Juan Carlos University, Av del Talgo 68, Madrid 28023, Spain
    Hum Reprod 24:496-501. 2009
    ....
  43. ncbi Surgery or assisted reproduction? A decision analysis of treatment costs in male infertility
    Maxwell V Meng
    Department of Urology, University of California San Francisco, San Francisco, California 94115 1695, USA
    J Urol 174:1926-31; discussion 1931. 2005
    ..We used formal decision analysis to estimate and compare the cost-effectiveness of surgical therapy and ART for varicocele and vasectomy reversal...
  44. ncbi Assisted reproductive technology and the incidence of ovarian cancer: a meta-analysis
    Sonya Kashyap
    Department of Community Medicine and Epidemiology, University of Ottawa, Ottawa, Ontario, Canada
    Obstet Gynecol 103:785-94. 2004
    ..To systematically evaluate the available literature regarding the relationship between assisted reproductive technology and ovarian cancer...
  45. ncbi Genomic imprinting and reproduction
    A K E Swales
    School of Biomedical and Clinical Laboratory Sciences, University of Edinburgh, Hugh Robson Building, George Square, Edinburgh EH8 9XD, UK
    Reproduction 130:389-99. 2005
    ..Recent studies have suggested a link between the use of assisted reproductive techniques and an increase in normally rare imprinting disorders...
  46. ncbi What is the most relevant standard of success in assisted reproduction? The next step to improving outcomes of IVF: consider the whole treatment
    E M E W Heijnen
    Division of Reproductive Medicine, Department of Obstetrics and Gynaecology, Erasmus Medical Centre, Rotterdam, The Netherlands
    Hum Reprod 19:1936-8. 2004
    ..If IVF success rates were to be expressed in terms of delivery of a term single baby per IVF treatment (or in a given treatment period), the introduction of single embryo transfer on a large scale would be facilitated...
  47. ncbi Fertility and ageing
    D T Baird
    Hum Reprod Update 11:261-76. 2005
    ..Pregnancies among women aged >40 years are associated with more non-severe complications, more premature births, more congenital malformations and more interventions at birth...
  48. ncbi Assisted reproductive technologies and the risk of birth defects--a systematic review
    Michèle Hansen
    Centre for Child Health Research, The University of Western Australia Telethon Institute for Child Health Research, West Perth, Western Australia 6872, Australia
    Hum Reprod 20:328-38. 2005
    ....
  49. ncbi Sperm DNA integrity assessment in prediction of assisted reproduction technology outcome
    M Bungum
    Fertility Clinic, Viborg Hospital, Skive, Denmark
    Hum Reprod 22:174-9. 2007
    ..The available data however, have been based on limited numbers of treatments. We aimed to define the clinical role of SCSA in assisted reproduction...
  50. ncbi Risks and complications in assisted reproduction techniques: Report of an ESHRE consensus meeting
    J A Land
    Department of Obstetrics and Gynecology, Academisch Ziekenhuis Maastricht, The Netherlands
    Hum Reprod 18:455-7. 2003
    ..The consensus meeting on Risks and Complications in ART held in Maastricht in May 2002 focused on four topics: multiple pregnancies, long-term effects of ART on women, effects of ART on offspring, and morbidity/mortality registries...
  51. ncbi Sperm selection in assisted reproductive techniques
    Uwe Paasch
    European Academy of Andrology Center, University of Leipzig, Philipp Rosenthal Str 23 25, 04103 Leipzig, Germany
    Soc Reprod Fertil Suppl 65:515-25. 2007
    ..Furthermore, sperm prepared according to this protocol showed improved ability to fertilise eggs using the hamster oocyte penetration assay...
  52. ncbi Limited importance of pre-embryo pronuclear morphology (zygote score) in assisted reproduction outcome in the absence of embryo cryopreservation
    Alessia Nicoli
    Centre of Reproductive Medicine, Department of Obstetrics and Gynecology, Arcispedale S Maria Nuova ASMN, Reggio Emilia, Italy
    Fertil Steril 88:1167-73. 2007
    ....
  53. ncbi Redefining the relationship between sperm deoxyribonucleic acid fragmentation as measured by the sperm chromatin structure assay and outcomes of assisted reproductive techniques
    John F Payne
    Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Fertil Steril 84:356-64. 2005
    ..structure assay (SCSA) DNA fragmentation index (DFI) values >27% would not achieve pregnancy with assisted reproductive techniques (ART) and to investigate how DFI and high DNA stainability (HDS), as measured by the SCSA, affect ..
  54. ncbi A review on reproductive biotechnologies for conservation of endangered mammalian species
    S M H Andrabi
    MC Franklin Laboratory, Faculty of Veterinary Science, The University of Sydney, Camden, NSW 2570, Australia
    Anim Reprod Sci 99:223-43. 2007
    This review describes the use of modern reproductive biotechnologies or assisted reproductive techniques (ART) including artificial insemination, embryo transfer/sexing, in vitro fertilization, gamete/embryo micromanipulation, semen ..
  55. ncbi Necessity of nuclear and mitochondrial genome analysis prior to assisted reproductive techniques/intracytoplasmic sperm injection
    Rakesh Kumar
    Laboratory of Molecular Reproduction and Genetics, Department of Anatomy, All India Institute of Medical Science AIIMS, N Delhi 110029, India
    Indian J Biochem Biophys 44:437-42. 2007
    ..Thus, genetic analysis is strongly recommend in all men with idiopathic infertility who opt for ART to counsel couples and provide them with most adapted therapeutics...
  56. ncbi Risk of spontaneous abortion in women with childhood exposure to parental cigarette smoke
    John D Meeker
    Department of Environmental Health Sciences, University of Michigan, Ann Arbor, MI 48109, USA
    Am J Epidemiol 166:571-5. 2007
    ..Future large studies of pregnancy loss are needed that can distinguish women's tobacco smoke exposure in childhood from that taking place in utero...
  57. ncbi Assisted reproductive technology surveillance--United States, 2000
    Victoria C Wright
    Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, USA
    MMWR Surveill Summ 52:1-16. 2003
    ..Multiple births are associated with increased risk for mothers and infants (e.g., pregnancy complications, premature delivery, low-birthweight infants, and long-term disability among infants)...
  58. ncbi Serum anti-Müllerian hormone and estradiol levels as predictors of ovarian hyperstimulation syndrome in assisted reproduction technology cycles
    Tsung Hsien Lee
    Department of Obstetrics and Gynecology, College of Medicine, National Taiwan University, Taipei, Taiwan, Republic of China
    Hum Reprod 23:160-7. 2008
    ..The objective of this study is to determine whether the serum AMH level can predict ovarian hyperstimulation syndrome (OHSS) prior to selection of COS protocols...
  59. ncbi Assisted reproductive technology in Europe, 2004: results generated from European registers by ESHRE
    A Nyboe Andersen
    ESHRE Central Office, Meerstraat 60, B 1852 Grimbergen, Belgium
    Hum Reprod 23:756-71. 2008
    European results of assisted reproductive techniques from treatments initiated during 2004 are presented in this eighth report.
  60. ncbi Maternal exposure to second-hand tobacco smoke and pregnancy outcome among couples undergoing assisted reproduction
    J D Meeker
    Department of Environmental Health Sciences, University of Michigan School of Public Health, Ann Arbor, MI 48109, USA
    Hum Reprod 22:337-45. 2007
    ..Exposure to second-hand tobacco smoke is preventable, yet common. This study assessed relationships between maternal exposure to second-hand tobacco smoke and adverse pregnancy outcomes...
  61. ncbi How to preserve fertility in young women exposed to chemotherapy? The role of GnRH agonist cotreatment in addition to cryopreservation of embrya, oocytes, or ovaries
    Zeev Blumenfeld
    Department of Obstetrics and Gynecology, Rambam Medical Center, Technion Faculty of Medicine, Haifa 31096, Israel
    Oncologist 12:1044-54. 2007
    ....
  62. ncbi Novel concepts of human chorionic gonadotropin: reproductive system interactions and potential in the management of infertility
    Marco Filicori
    Reproductive Endocrinology Center, University of Bologna, Bologna, Italy
    Fertil Steril 84:275-84. 2005
    ..To extensively review the scientific literature on the potential sites of hCG action and the role of this hormone on reproductive processes not necessarily related to the classic hCG functions of supporting early pregnancy...
  63. ncbi Psychosocial adjustment during pregnancy for older couples conceiving through assisted reproductive technology
    Catherine A McMahon
    Psychology Department, Macquarie University, North Ryde, NSW, Australia
    Hum Reprod 22:1168-74. 2007
    ..This study explores differences in psychosocial adjustment during pregnancy in older (maternal age >or= 38 years) and younger (maternal age < 35 years) couples after assisted reproductive technology (ART) conception...
  64. ncbi In vitro maturation of oocytes
    G Durga Rao
    Clinical Research Fellow, McGill University, Royal Victoria Hospital, Montreal, Canada
    Semin Reprod Med 23:242-7. 2005
    ..We have achieved a 38% clinical pregnancy rate per cycle in women having IVM for infertility treatment up to the age of 35 years, and 50% clinical pregnancy rate per cycle in recipients of IVM egg donation...
  65. ncbi Use of complementary and alternative medicines associated with a 30% lower ongoing pregnancy/live birth rate during 12 months of fertility treatment
    J Boivin
    School of Psychology, Cardiff University, Tower Building, Park Place, Cardiff, Wales CF10 3AT, UK
    Hum Reprod 24:1626-31. 2009
    ..We therefore compared ongoing pregnancy and live birth rate in spontaneous users and non-users of CAM during a 12-month period of assisted reproduction technique (ART) treatment. Consent was by questionnaire return...
  66. ncbi Cytogenetic analysis of early nonviable pregnancies after assisted reproduction treatment
    M Carmen Martinez
    Instituto Valenciano de Infertilidad in Murcia, Murcia, Spain
    Fertil Steril 93:289-92. 2010
    ....
  67. ncbi The effect of the 2004 Italian law on outcomes of assisted reproduction technology in severe male factor infertility
    G B La Sala
    Department of Obstetrics and Gynecology, Arcispedale Santa Maria Nuova, Viale Risorgimento 80, 42100 Reggio Emilia, Italy
    Reprod Biomed Online 20:2-10. 2010
    ..It is hoped that the Italian assisted reproductive technologies law is altered as soon as possible, allowing the insemination of more than three oocytes...
  68. ncbi Absence of conclusive evidence for the safety and efficacy of gonadotropin-releasing hormone analogue treatment in protecting against chemotherapy-induced gonadal injury
    Kutluk Oktay
    Department of Obstetrics and Gynecology, Joan and Sanford I Weill Medical College of Cornell University, 505 East 70th Street, HT 340, New York, New York 10021, USA
    Oncologist 12:1055-66. 2007
    ..In this manuscript, we debate the rationale for the effectiveness of GnRH analogue coadministration in preservation of fertility by reviewing the literature, and provide preliminary data to support our views...
  69. ncbi Expected poor ovarian response in predicting cumulative pregnancy rates: a powerful tool
    Dave J Hendriks
    Department of Reproductive Medicine, Division of Obstetrics, Neonatology and Gynecology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Reprod Biomed Online 17:727-36. 2008
    ..However, if such poor response has been expected, further treatment may be avoided because of an unfavourable prognosis for pregnancy...
  70. ncbi The effect of legislation on outcomes of assisted reproduction technology: lessons from the 2004 Italian law
    Giovanni Battista La Sala
    Department of Obstetrics and Gynecology, Arcispedale Santa Maria Nuova, Reggio Emilia, Italy
    Fertil Steril 89:854-9. 2008
    ..To evaluate the effect of the 2004 Italian regulations (insemination of <or=3 oocytes/cycle, transfer of all embryos, prohibition of embryo cryopreservation) on outcomes of assisted reproduction treatment (ART)...
  71. ncbi Assisted reproductive practice: religious perspectives
    Joscph G Schenker
    Department of Obstetrics and Gynecology, Hebrew University, Hadassah Medical Centre, Jerusalem, Israel
    Reprod Biomed Online 10:310-9. 2005
    ....
  72. ncbi Dynamics of HIV viral load in blood and semen of patients under HAART: impact of therapy in assisted reproduction procedures
    Giovanni Battista La Sala
    Division of Obstetrics, Gynecology and Reproduction Medicine, ASMN Reggio Emilia, Italy
    AIDS 21:377-9. 2007
    ..001). These findings emphasize the negative role of HAART, but not of HIV-1 infection, in determining semen alterations...
  73. ncbi Current aspects of blastocyst cryopreservation
    M Youssry
    Department of Obstetrics and Gynecology, University of Schleswig Holstein, Lubeck, Germany
    Reprod Biomed Online 16:311-20. 2008
    ..The aim of this review is to focus on the cryopreservation of human blastocysts using slow and rapid protocols and to assess the impact of the crypreservation protocol used on the survival, implantation and pregnancy rates...
  74. ncbi Intra-follicular leptin concentration as a predictive factor for in vitro oocyte fertilization in assisted reproductive techniques
    G De Placido
    Department of Obstetrics Gynecology and Reproductive Medicine, University of Naples Federico II, 80128 Naples, Italy
    J Endocrinol Invest 29:719-26. 2006
    ..role of follicular fluid (FF) leptin concentration in predicting oocyte fertilization and embryo quality was evaluated in 35 normogonadotrophic women undergoing controlled ovarian stimulation (COS) for assisted reproductive techniques.
  75. ncbi Assisted reproductive technology treatment costs of a live birth: an age-stratified cost-outcome study of treatment in Australia
    Georgina M Chambers
    School of Women s and Children s Health, University of New South Wales, Sydney, NSW, Australia
    Med J Aust 184:155-8. 2006
    ..To calculate the cost of assisted reproductive technology (ART) treatment cycles and resultant live-birth events...
  76. ncbi Outcomes from assisted reproductive technology
    Bradley J Van Voorhis
    Department of Obstetrics and Gynecology, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242 1080, USA
    Obstet Gynecol 107:183-200. 2006
    ..All outcomes of ART, including pregnancy rates and adverse complications, need to be compared with standard non-ART therapy when deciding the appropriate course of treatment for a given couple...
  77. ncbi Treatment strategies in assisted reproduction for women of advanced maternal age
    Colin M Howles
    Serono International SA, Department of Product Development, Geneva, Switzerland
    Int Surg 91:S37-54. 2006
    ..Further studies are required to investigate the physiological mechanisms behind this observation and to assess the possible effect of LH and/or hGH supplementation on the age-related decline in pregnancy rate...
  78. ncbi Preimplantation genetic screening does not improve delivery rate in women under the age of 36 following single-embryo transfer
    C Staessen
    Centre for Medical Genetics, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium
    Hum Reprod 23:2818-25. 2008
    ..Besides the morphological quality and embryo kinetics up to the blastocyst stage, preimplantation genetic screening (PGS) of aneuploidy has been advocated as an adjuvant approach to select the embryo...
  79. ncbi Ultrasound assessment of the uterus and fallopian tube in infertile women
    Bradley J Van Voorhis
    Department of Obstetrics and Gynecology, University of Iowa Hospitals, Iowa City, Iowa 52242, USA
    Semin Reprod Med 26:232-40. 2008
    ..Understanding and interpreting the significance of the lesions is a major clinical challenge in the infertile patient...
  80. pmc Human oocyte vitrification: the permeability of metaphase II oocytes to water and ethylene glycol and the appliance toward vitrification
    Steven F Mullen
    Comparative Medicine Center and Department of Veterinary Pathobiology, University of Missouri at Columbia, Columbia, Missouri 65211, USA
    Fertil Steril 89:1812-25. 2008
    ..To determine the permeability of human metaphase II oocytes to ethylene glycol and water in the presence of ethylene glycol, and to use this information to develop a method to vitrify human oocytes...
  81. ncbi Relationship between pre-embryo pronuclear morphology (zygote score) and standard day 2 or 3 embryo morphology with regard to assisted reproductive technique outcomes
    John F Payne
    Department of Obstetrics and Gynecology, Duke University Medical Center, Durham, North Carolina 27710, USA
    Fertil Steril 84:900-9. 2005
    ..To test the hypothesis that pregnancy rates are low if grade Z1 pre-embryos are not available for transfer and to determine if pronuclear morphology is a better predictor of pregnancy than traditional embryo morphology...
  82. pmc Do intrauterine or genetic influences explain the foetal origins of chronic disease? A novel experimental method for disentangling effects
    Anita Thapar
    Department of Psychological Medicine, School of Medicine, Heath Park, Cardiff University, UK
    BMC Med Res Methodol 7:25. 2007
    ..However disentangling these effects in humans poses significant problems for traditional genetic epidemiological research designs...
  83. ncbi Routine office hysteroscopy in the investigation of infertile couples before assisted reproduction
    Ana Carolina Japur de Sá Rosa e de Silva
    Department of Obstetrics and Gynecology, Ribeirao Preto School of Medicine, University of Sao Paulo, Sao Paulo, Brazil
    J Reprod Med 50:501-6. 2005
    ..To evaluate the need for office hysteroscopy in routine investigations of infertile couples prior to assisted reproduction (AR)...
  84. ncbi Outcome of laser-assisted polar body biopsy and aneuploidy testing
    Markus Montag
    Department of Gynecological Endocrinology and Reproductive Medicine, University Clinics of Bonn, Germany
    Reprod Biomed Online 9:425-9. 2004
    ..3% per transfer cycle. It is concluded that polar body biopsy using a diode laser system is as efficient as standard polar body biopsy using zona drilling...
  85. ncbi Current concepts and novel applications of LH activity in ovarian stimulation
    Marco Filicori
    Reproductive Endocrinology Center, University of Bologna, Via Massarenti 13, 40138 Bologna, Italy
    Trends Endocrinol Metab 14:267-73. 2003
    ....
  86. ncbi Lack of standardization in performance of the semen analysis among laboratories in the United States
    Brooks A Keel
    Department of Obstetrics and Gynecology, Women s Research Institute, University of Kansas School of Medicine, Wichita, USA
    Fertil Steril 78:603-8. 2002
    ..To determine the level of standardization in performance of the semen analysis among clinical laboratories in the United States...
  87. ncbi Randomized trial to compare the effect of recombinant human FSH (follitropin alfa) with or without recombinant human LH in women undergoing assisted reproduction treatment
    R Marrs
    California Fertility Partners, Santa Monica, CA, USA
    Reprod Biomed Online 8:175-82. 2004
    ..Younger patients therefore do not seem to benefit from an LH-supplemented ovarian stimulation protocol, but women >or=35 years undergoing assisted reproduction may benefit from using r-hLH in addition to r-hFSH...
  88. ncbi Assisted reproduction in HIV-1-serodifferent couples: the need for viral validation of processed semen
    Marianne Leruez-Ville
    Laboratoire de Virologie, CHU Necker Enfants Malades, Paris, France
    AIDS 16:2267-73. 2002
    ..Potential HIV contamination of selected spermatozoa after semen processing is an important issue in this context...
  89. ncbi Assisted reproductive technology in Europe, 1999. Results generated from European registers by ESHRE
    K G Nygren
    Hum Reprod 17:3260-74. 2002
    European results of assisted reproductive techniques from treatments initiated during 1999, are presented in this third report. Data were collected mainly from pre-existing national registers...
  90. ncbi Contribution of sperm molecular features to embryo quality and assisted reproduction success
    Nicolas Garrido
    Instituto Universitario IVI and FIVI, Andrology Laboratory and Semen Bank, Plaza de la Policia Local 3, Valencia 46015, Spain
    Reprod Biomed Online 17:855-65. 2008
    ..In this context, a complex molecular tool designed to analyse a battery of parameters seems to be necessary...
  91. ncbi What is the most relevant standard of success in assisted reproduction? Is there a single 'parameter of excellence'?
    Anja Pinborg
    The Fertility Clinic, University of Copenhagen, Rigshospitalet, Blegdamsvej 9, 2100 Copenhagen, Denmark
    Hum Reprod 19:1052-4. 2004
    ..If these standards are implemented as national gold standards, the future goal of homogeneous reporting of success rates in ART is within reach...
  92. ncbi Pronuclear scoring as a predictor of embryo development
    Lynette Scott
    University of Washington Medical School, Department of Obstetrics and Gynecology, Fertility and Endocrinology Centre, 4225 Roosevelt Way, NE Seattle, WA 98105, USA
    Reprod Biomed Online 6:201-14. 2003
    ..The use of PN scoring can help predict embryos that have poor developmental potential, aid in early selection and may indicate the health of the oocyte...
  93. ncbi Trends in multiple births conceived using assisted reproductive technology, United States, 1997-2000
    Meredith A Reynolds
    Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341 3717, USA
    Pediatrics 111:1159-62. 2003
    ..To examine trends in multiple births conceived using assisted reproductive technology (ART) in the United States between 1997 and 2000 and to estimate the proportion of all US multiple births attributable to ART use...
  94. ncbi A randomized, double-blind, multicentre clinical trial comparing starting doses of 150 and 200 IU of recombinant FSH in women treated with the GnRH antagonist ganirelix for assisted reproduction
    Henk J Out
    Organon International, PO Box 20, 5340 BH Oss, The Netherlands
    Hum Reprod 19:90-5. 2004
    ..In this study it was investigated whether an increase in the starting dose of recombinant FSH (rFSH) could compensate for this loss...
  95. ncbi Spontaneous abortion among pregnancies conceived using assisted reproductive technology in the United States
    Laura A Schieve
    Division of Reproductive Health, National Center for Chronic Disease Prevention and Health Promotion, Centers for Disease Control and Prevention, Atlanta, Georgia 30341
    Obstet Gynecol 101:959-67. 2003
    ..To examine rates and risk factors for spontaneous abortion among pregnancies conceived using assisted reproductive technology (ART)...
  96. ncbi Associated multiple gestation--ART
    Jean Cohen
    Centre de Sterilite, Hospital de Sevres, Paris, France
    Clin Obstet Gynecol 46:363-74. 2003
  97. ncbi The risk of birth defects in children born after assisted reproductive technologies
    Jennifer J Kurinczuk
    National Perinatal Epidemiology Unit, University of Oxford, UK
    Curr Opin Obstet Gynecol 16:201-9. 2004
    ..This review addresses the question of whether there is evidence of an increased risk of birth defects in children born following assisted reproductive technologies compared with spontaneously conceived children...
  98. ncbi Research hurdles complicating the analysis of infertility treatment and child health
    G M Buck Louis
    Epidemiology Branch, Division of Epidemiology, Statistics and Prevention Research, National Institute of Child Health and Human Development, The National Institutes of Health, Department of Health and Human Services, Rockville, MD 20852, USA
    Hum Reprod 20:12-8. 2005
    ..Longitudinal studies of children conceived with ART will benefit from attention to these issues and, hopefully, produce answers to lingering questions about safety...
  99. ncbi New reproductive technologies, ethics and legislation in Brazil: a delayed debate
    D Guilhem
    AOS Quadra 04 Bloco B Apt 617, Brasilia, DF Brazil, CEP 70660 042
    Bioethics 15:218-30. 2001
    ..Very little attention has been directed to the issues of sexual and reproductive rights and to the health of the women submitted to the new reproductive techologies [sic]...
  100. ncbi Infertility therapy-associated multiple pregnancies (births): an ongoing epidemic
    Eli Y Adashi
    University of Utah Health Sciences Center, Department of Obstetrics and Gynecology, Salt Lake City, Utah, USA
    Reprod Biomed Online 7:515-42. 2003
  101. ncbi Can varicocelectomy significantly change the way couples use assisted reproductive technologies?
    Selahittin Cayan
    Department of Urology, University of Mersin School of Medicine, Mersin and University of Istanbul, Turkey
    J Urol 167:1749-52. 2002
    ..We assessed how varicocelectomy alters semen quality in a large cohort of infertile men and determined whether it can change patient candidacy for assisted reproductive technology procedures...

Research Grants62

  1. Trapping Cumulus Products for Contraceptive Targeting
    John Eppig; Fiscal Year: 2006
    ..abstract_text> ..
  2. Analysis of epigenetic regulation in early mammalian embryos via RNA interference
    Charles R Long; Fiscal Year: 2010
    ..congenital abnormalities and increased susceptibility to disease associated with both human assisted reproductive techniques and spontaneous conception...
  3. YOUNG FROM STORED AND IMPAIRED MOUSE SPERM
    John Biggers; Fiscal Year: 2001
    The aim of this proposal is to develop an algorithm using assisted reproductive techniques to reconstitute valuable genetic strains of mice from stored spermatozoa...
  4. COOPERATIVE MULTICENTER REPRODUCTIVE MEDICINE NETWORK
    PETER MCGOVERN; Fiscal Year: 2004
    ..Technological advances have made therapy for infertility quite effective. However, all of the assisted reproductive techniques require the use of gonadotropins (whether recombinant or derived from menopausal urine) to induce ..
  5. Regulation of Meiotic Arrest in Oocytes by G-Proteins
    LISA MEHLMANN; Fiscal Year: 2004
    ..Understanding how the oocyte cell cycle is regulated within the follicle may find applications to practical problems including assisted reproductive techniques, contraception, and infertility.
  6. Epigenetic Regulation of Gene Expression During Early Mouse Embryogenesis
    M Smith; Fiscal Year: 2007
    ..will have a significant impact on how we think about, and manage, a wide range of human health issues including assisted reproductive techniques, somatic nuclear transfer, and stem cell therapy. [unreadable] [unreadable] [unreadable]
  7. The ARTs in Action in Nonhuman Primates
    Don Wolf; Fiscal Year: 2003
    ..This arrangement will permit attendees to attend both meetings and should encourage participation by research trainees and fellows. ..
  8. NUCLEAR TRANSFER IN RHESUS MONKEYS
    Don Wolf; Fiscal Year: 2001
    ..Also, the simplicity of separating IVF-produced embryos at early cleavage stages with the transfer of individual blastomeres or groups of blastomeres to surrogate zonae offers a low technology method of cloning that will be evaluated. ..
  9. EVALUATION OF THE POTENCY OF RHESUS MONKEY STERM CELLS
    Don Wolf; Fiscal Year: 2001
    ..abstract_text> ..
  10. PROPAGATION OF MONKEY MODELS OF HUMAN DISEASE
    Shoukhrat Mitalipov; Fiscal Year: 2005
    ..The applicants will select the optimal approach to twinning in year 1 and produce 5 sets of identical twins per year during years 2-5 of the study. ..
  11. Preimplantation Genetic Diagnosis & Genetic Modification
    John Robertson; Fiscal Year: 2003
    ..It will explore whether prevailing conceptions of procreative and family liberty include the right of prospective parents to alter or modify the genome of offspring for medical or non-medical purposes. ..
  12. Plurality and Contemporary Infant Mortality Risks
    Barbara Luke; Fiscal Year: 2006
    ..abstract_text> ..
  13. Maternal Morbidity and Mortality in Multiple Pregnancy
    Barbara Luke; Fiscal Year: 2006
    ..The main hypothesis of this proposal is that higher plurality is the predominant factor affecting maternal morbidity and mortality, further potentated by older maternal age and primiparity. ..
  14. Supporting Human ART Through Basic Science
    Barry Bavister; Fiscal Year: 2004
    ..This Symposium will attract members of the human ART community and scientists working in animal ART, and will provide a basis for continued and expanded interactions between these two groups. ..
  15. IMPROVING COMMUNICATION WITH IVF PATIENTS ABOUT RISKS SUCH AS MULTIPLE BIRTHS
    LINDA FRAZIER; Fiscal Year: 2008
    ..The new materials will also help couples who achieve pregnancy to manage risks for increased maternal and neonatal problems among IVF singletons and multiples. [unreadable] [unreadable] [unreadable]..
  16. EMBRYO TECHNOLOGIES FOR PROPAGATION OF RHESUS MONKEYS
    Barry Bavister; Fiscal Year: 2006
    ..abstract_text> ..
  17. Improving Employment among Gynecologic Cancer Survivors
    LINDA FRAZIER; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  18. BIOLOGICAL BASIS OF THE PERIMENOPAUSE
    DAVID SEIFER; Fiscal Year: 2002
    ....
  19. ES CELL MODEL FOR PLACENTAL DEVELOPMENT
    Thaddeus Golos; Fiscal Year: 2006
    ..This proposal will allow us to develop the tools to advance a novel system for the study of primate placental biology. [unreadable] [unreadable]..
  20. DNA methylation programming to oocyte environment
    Kevin Sinclair; Fiscal Year: 2007
    ..abstract_text> ..
  21. Views and Approaches Toward Research Integrity Among IRBs
    Robert Klitzman; Fiscal Year: 2007
    ..We anticipate that the data from this study will serve as a significant foundation in assisting future research and the improvement of Rl through guidelines, education and other capacity building. [unreadable] [unreadable] [unreadable]..
  22. How do oocytes & embryos cope with adverse environments?
    Jeremy Thompson; Fiscal Year: 2007
    ..This knowledge will also assist health professionals develop strategies to reduce the risk of adult onset diseases caused by perturbed early development. ..
  23. Chromosomal anomalies in macaque monkey oocytes
    Carol Brenner; Fiscal Year: 2006
    ..The information to be derived can be used to modify current ART protocols to reduce the frequency of artificially induced chromosome errors in embryos produced in vitro. ..
  24. Treatment of Endometriosis-Associated Pelvic Pain
    David Guzick; Fiscal Year: 2007
    ..In addition, a cost-effectiveness analysis will be performed by calculating the cost per unit reduction in pain score for each treatment. ..
  25. Oxidative Stress and Oocyte Development
    CATHERINE COMBELLES; Fiscal Year: 2007
    ..These findings will enhance our ability to detect and produce oocytes of optimal quality, thereby providing critical foundations for the improvement of female reproductive health. [unreadable] [unreadable] [unreadable]..
  26. Influences of the prenatal environment on metabolic programming
    KELLIE TAMASHIRO; Fiscal Year: 2008
    ..abstract_text> ..
  27. Molecular Mechanisms of FOXL2, An Ovarian Failure Gene
    Margareta Pisarska; Fiscal Year: 2010
    ..The proposed study could provide a better understanding of the mechanisms underlying premature ovarian failure. ..
  28. Binge Ethanol and Oocyte Quality
    Catherine A Vandevoort; Fiscal Year: 2010
    ..The outcome of this project will have direct relevance to the effects of binge drinking in women. ..
  29. UTERINE NK CELLS IN PRIMATE PREGNANCY
    Thaddeus G Golos; Fiscal Year: 2010
    ..for an important role of placental MHC class I molecules in the maternal immunological response to pregnancy in primates, and will further study the mechanisms and significance of these responses with two specific aims: ..
  30. RISK FACTORS AS PREDICTORS OF ECTOPIC PREGNANCY
    Kurt T Barnhart; Fiscal Year: 2010
    ....
  31. KLHL 10-mediated uniquitination during spermiogenesis
    Wei Yan; Fiscal Year: 2010
    ..On the other hand, KLHL10 and its substrate proteins may be good targets for future non-hormonal male contraceptives. ..
  32. Food intake and obesity in cloned mice
    Randall R Sakai; Fiscal Year: 2010
    ..In addition, the behavioral, physiological, and neurochemical data obtained will enhance our understanding of the mechanisms of obesity, a serious and growing chronic public health issue worldwide. ..
  33. A PRIMATE ES CELL MODEL FOR EMBRYO IMPLANTATION
    Thaddeus Golos; Fiscal Year: 2009
    ..abstract_text> ..
  34. Effects of Fetal Bisphenol A Exposure on Oogenesis in Primates
    CATHERINE A contact VANDEVOORT; Fiscal Year: 2010
    ..Because the dose used will be similar to current human blood levels of BPA, the results should have direct relevance to human health. ..
  35. Bridges to the Doctorate in Reproductive Biology
    Fuller Bazer; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  36. PROTOCOLS FOR MATURING AND FREEZING MONKEY OOCYTES
    Catherine VandeVoort; Fiscal Year: 2006
    ..abstract_text> ..
  37. Genetically Modified Rhesus Monkeys
    Shoukhrat Mitalipov; Fiscal Year: 2006
    ..Such animals should provide a resource for the study of human neurogenetic diseases and serve as pre-clinical models for new experimental treatments including gene and stem cell based therapies. ..
  38. BAYLOR BIRCWH PROGRAM
    Joe Simpson; Fiscal Year: 2004
    ..These goals are vital to public health in contributing to the establishment of methods for production of safe, effective, quality herbal extracts for consumer use. ..
  39. U of R Human Subjects Collaborative Research Enhancement
    David Guzick; Fiscal Year: 2003
    ..This can be viewed as the first steps in the development of an interoperative clinical research network as envisioned within the NIH Strategic Plan. ..
  40. GENOMIC & NONGENOMIC EFFECTS OF STEROIDS ON SALT INTAKE
    Randall Sakai; Fiscal Year: 2004
    ....
  41. Confocal Live Cell Imaging Instrument
    WILLIAM KINSEY; Fiscal Year: 2004
    ..He will also study calcium transients in granulosa cells induced to divide in vitro with tumor necrosis factor alpha. ..
  42. EXTRAMURAL RESEARCH FACILITIES IMPROVEMENT PROGRAM
    David Guzick; Fiscal Year: 2003
    ..Since much of the current space will continue to house vision science, this C06 award will create a substantial net increase in vision-research facilities and capabilities. ..
  43. THE MAJOR ANGIOGENIC FACTORS IN PLACENTAL ANGIOGENESIS
    Lawrence Reynolds; Fiscal Year: 2004
    ..abstract_text> ..
  44. Cognitive dysfunction in neuropsychiatric-SLE
    Michael Lockshin; Fiscal Year: 2002
    ..Successful completion of this research will redefine the pathogenesis of cognitive dysfunction and suggest therapeutic targets for intervention...
  45. PROTEIN PAINTING OF PREIMPLANTATION EMBRYOS
    Carol Warner; Fiscal Year: 2003
    ..Protein painting may ultimately be applied to create better conditions for modulating preimplantation embryonic growth or death, leading to enhanced pregnancy outcome or a new contraceptive technology. ..
  46. STRATEGIES FOR PRIMATE TRANSGENESIS
    Thaddeus Golos; Fiscal Year: 2003
    ..abstract_text> ..
  47. CELLULAR MECHANISMS OF OVARIAN TERATOCARCINOGENESIS
    John Eppig; Fiscal Year: 2002
    ..The chromosomal locations of genes producing metaphase I arrest and spontaneous parthenogenetic activation will be mapped with the goal of identifying and testing candidate genes that produce these abnormal phenotypes. ..
  48. National Black Leadership Conference on Genetics
    Kathy Hudson; Fiscal Year: 2004
    ..The Conference will be held in Washington DC in May 2004. ..
  49. HITACHI S-3000N VP SCANNING ELECTRON MICROSCOPE
    John Eppig; Fiscal Year: 2001
    ..abstract_text> ..
  50. COOPERATIVE MULTI CENTER REPRODUCTIVE MEDICINE NETWORK
    Evan Myers; Fiscal Year: 2005
    ..abstract_text> ..
  51. A Primate Model of Maternal Fetal Immune Tolerance
    Thaddeus Golos; Fiscal Year: 2006
    ..The successful implementation of our recent adaptation of transgenic technology to the primate placenta will provide unprecedented opportunity for novel models of primate placental biology. ..
  52. Role of integrins and activin in granulosa cell growth
    Kutluk Oktay; Fiscal Year: 2007
    ..Cell proliferation and survival will be determined before and after transfection with the dominant-negative mutants. ..
  53. A Program for Expanding ELSI Undergraduate Pedagogy
    Ronald Green; Fiscal Year: 2005
    ..This proposal represents a logical next step in the employment of the skills and resources we have developed at Dartmouth for undergraduate ELSI education. ..
  54. Social stress-induced changes in energy homeostasis
    KELLIE TAMASHIRO; Fiscal Year: 2005
    ..abstract_text> ..
  55. MHC-Defined and Identical Twin Monkeys for Research
    Joseph Kemnitz; Fiscal Year: 2005
    ..Additionally, genetically identical macaques will have general utility in biomedical research, especially to the neuroscience community. ..
  56. PED GENE ACTION IN DEVELOPMENT AND REPRODUCTION
    Carol Warner; Fiscal Year: 2005
    ..This hypothesis will be tested in the third specific aim by using an HLA-G transgenic mouse system. ..
  57. Views of Privacy of Genetic Information
    Robert Klitzman; Fiscal Year: 2005
    ..The findings of this study can enhance further policy, professional and public education, and future research in this area. ..
  58. OVINE INTERFERON-TAU REGULATES UTERINE HORMONE RECEPTOR
    Fuller Bazer; Fiscal Year: 2005
    ....
  59. PGD: Couples Decision Making at the Genetic and Reproductive Interface
    Patricia Hershberger; Fiscal Year: 2009
    ....
  60. Deep Brain Stimulation for Disorders of Mood Thought and Behavior: Scientific an
    DEBRA MATHEWS; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..