spinal puncture

Summary

Summary: Tapping of the subarachnoid space in the lumbar region, usually between the third and fourth lumbar vertebrae.

Top Publications

  1. ncbi Pneumocephalus complicated by postdural puncture headache after unintentional dural puncture
    Ivan A Velickovic
    Anesth Analg 104:747-8. 2007
  2. ncbi Diagnosis and management of idiopathic normal-pressure hydrocephalus: a prospective study in 151 patients
    Anthony Marmarou
    Department of Neurosurgery, Virginia Commonwealth University Medical Center, Richmond, Virginia 23219 0449, USA
    J Neurosurg 102:987-97. 2005
  3. ncbi A more efficient enzyme-linked immunosorbent assay for measurement of alpha-synuclein in cerebrospinal fluid
    Wieneke J A van Geel
    Laboratory of Pediatrics and Neurology, Radboud University Nijmegen Medical Centre, The Netherlands
    J Neurosci Methods 168:182-5. 2008
  4. ncbi Risk of bacterial or herpes simplex virus meningitis/encephalitis in children with complex febrile seizures
    L Barry Seltz
    Division of Pediatric Medicine and the Pediatric Outcomes Research Team, Department of Pediatrics, The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada
    Pediatr Emerg Care 25:494-7. 2009
  5. ncbi Simple febrile seizures: are the AAP guidelines regarding lumbar puncture being followed?
    Oranit Shaked
    Division of Emergency Medicine, Department of Pediatrics, Miami Children s Hospital, Miami, FL 33155, USA
    Pediatr Emerg Care 25:8-11. 2009
  6. ncbi Yield of lumbar puncture among children who present with their first complex febrile seizure
    Amir Kimia
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Pediatrics 126:62-9. 2010
  7. ncbi Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis
    Lise E Nigrovic
    Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatrics 122:726-30. 2008
  8. ncbi Effect of delayed lumbar punctures on the diagnosis of acute bacterial meningitis in adults
    Benedict Michael
    The Walton Centre for Neurology and Neurosurgery NHS Trust, Liverpool, UK
    Emerg Med J 27:433-8. 2010
  9. pmc A population based study of the impact of corticosteroid therapy and delayed diagnosis on the outcome of childhood pneumococcal meningitis
    P B McIntyre
    National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, The Children s Hospital at Westmead and University of Sydney, NSW, Australia
    Arch Dis Child 90:391-6. 2005
  10. ncbi Idiopathic intracranial hypertension
    Deborah I Friedman
    Departments of Ophthalmology and Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    J Neuroophthalmol 24:138-45. 2004

Research Grants

Detail Information

Publications208 found, 100 shown here

  1. ncbi Pneumocephalus complicated by postdural puncture headache after unintentional dural puncture
    Ivan A Velickovic
    Anesth Analg 104:747-8. 2007
  2. ncbi Diagnosis and management of idiopathic normal-pressure hydrocephalus: a prospective study in 151 patients
    Anthony Marmarou
    Department of Neurosurgery, Virginia Commonwealth University Medical Center, Richmond, Virginia 23219 0449, USA
    J Neurosurg 102:987-97. 2005
    ....
  3. ncbi A more efficient enzyme-linked immunosorbent assay for measurement of alpha-synuclein in cerebrospinal fluid
    Wieneke J A van Geel
    Laboratory of Pediatrics and Neurology, Radboud University Nijmegen Medical Centre, The Netherlands
    J Neurosci Methods 168:182-5. 2008
    ....
  4. ncbi Risk of bacterial or herpes simplex virus meningitis/encephalitis in children with complex febrile seizures
    L Barry Seltz
    Division of Pediatric Medicine and the Pediatric Outcomes Research Team, Department of Pediatrics, The Hospital for Sick Children, 555 University Avenue, Toronto, ON M5G 1X8, Canada
    Pediatr Emerg Care 25:494-7. 2009
    ..To estimate the rates of bacterial meningitis and herpes simplex virus (HSV) encephalitis in children presenting with complex febrile seizures...
  5. ncbi Simple febrile seizures: are the AAP guidelines regarding lumbar puncture being followed?
    Oranit Shaked
    Division of Emergency Medicine, Department of Pediatrics, Miami Children s Hospital, Miami, FL 33155, USA
    Pediatr Emerg Care 25:8-11. 2009
    ..In 1996, the American Academy of Pediatrics (AAP) published a practice parameter recommending that lumbar puncture (LP) be strongly considered in infants younger than 12 months presenting with a first febrile seizure...
  6. ncbi Yield of lumbar puncture among children who present with their first complex febrile seizure
    Amir Kimia
    Division of Emergency Medicine, Department of Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Pediatrics 126:62-9. 2010
    ..To assess the rate of acute bacterial meningitis (ABM) among children who present with their first complex febrile seizure (CFS)...
  7. ncbi Effect of antibiotic pretreatment on cerebrospinal fluid profiles of children with bacterial meningitis
    Lise E Nigrovic
    Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatrics 122:726-30. 2008
    ..The goal of this study was to evaluate the effect of antibiotic administration before lumbar puncture on cerebrospinal fluid profiles in children with bacterial meningitis...
  8. ncbi Effect of delayed lumbar punctures on the diagnosis of acute bacterial meningitis in adults
    Benedict Michael
    The Walton Centre for Neurology and Neurosurgery NHS Trust, Liverpool, UK
    Emerg Med J 27:433-8. 2010
    ..In such patients, CT scanning before LP is not needed...
  9. pmc A population based study of the impact of corticosteroid therapy and delayed diagnosis on the outcome of childhood pneumococcal meningitis
    P B McIntyre
    National Centre for Immunisation Research and Surveillance of Vaccine Preventable Diseases, The Children s Hospital at Westmead and University of Sydney, NSW, Australia
    Arch Dis Child 90:391-6. 2005
    ..Despite an extensive literature, the impact of both adjunctive steroid therapy and delayed diagnosis on the outcome of childhood pneumococcal meningitis is controversial...
  10. ncbi Idiopathic intracranial hypertension
    Deborah I Friedman
    Departments of Ophthalmology and Neurology, University of Rochester School of Medicine and Dentistry, Rochester, New York, USA
    J Neuroophthalmol 24:138-45. 2004
    ..Although the pathogenesis of this condition remains unknown, diagnostic and therapeutic developments during the past two decades have substantially advanced patient management...
  11. ncbi Interest of dual-task-related gait changes in idiopathic normal pressure hydrocephalus
    S Armand
    Willy Taillard Laboratory of Kinesiology, Geneva University Hospitals and University of Geneva Care Services Directorate, Unit of Physiotherapy Research, Geneva, Switzerland
    Eur J Neurol 18:1081-4. 2011
    ..e. dual tasking). The current study assessed the effect of cerebrospinal fluid (CSF) tapping on quantitative gait modification during single and dual tasking in patients with a suspicion of iNPH...
  12. pmc Lumbar puncture following febrile convulsion
    W Carroll
    The Neonatal Unit, City General Hospital, Stoke on Trent, UK
    Arch Dis Child 87:238-40. 2002
  13. ncbi Incidence of post-lumbar puncture syndrome reduced by reinserting the stylet: a randomized prospective study of 600 patients
    M Strupp
    Department of Neurology, Ludwig Maximilians University of Munich, Klinikum Grosshadern, Germany
    J Neurol 245:589-92. 1998
    ..This significant difference (16.3 vs 5.0%, P < 0.005, chi square test) supports our hypothesis. On the basis of our results, we recommend reinserting the stylet before removing the needle in order to reduce the incidence of PLPS...
  14. ncbi The low rate of bacterial meningitis in children, ages 6 to 18 months, with simple febrile seizures
    Jeffrey Hom
    Department of Emergency Medicine, New York University School of Medicine, NY, USA
    Acad Emerg Med 18:1114-20. 2011
    ..The study population consists of fully immunized children between ages 6 and 18 months of age with an unremarkable history and normal physical examination...
  15. pmc Use of clinical syndromes to target antibiotic prescribing in seriously ill children in malaria endemic area: observational study
    James A Berkley
    Centre for Geographic Medicine Research Coast, PO Box 230, Kilifi, Kenya
    BMJ 330:995. 2005
    ..To determine how well antibiotic treatment is targeted by simple clinical syndromes and to what extent drug resistance threatens affordable antibiotics...
  16. ncbi Diagnosis of acute bacterial meningitis in children at a district hospital in sub-Saharan Africa
    J A Berkley
    Centre for Geographic Medicine Research Coast, PO Box 230, Kilifi, Kenya
    Lancet 357:1753-7. 2001
    ..We have assessed the value of non-laboratory tests and incomplete laboratory data in diagnosing childhood acute bacterial meningitis in this setting...
  17. ncbi Utility of lumbar puncture for first simple febrile seizure among children 6 to 18 months of age
    Amir A Kimia
    Division of Emergency Medicine, Children s Hospital Boston, Boston, MA 02115, USA
    Pediatrics 123:6-12. 2009
    ..Our aims were to determine compliance with these recommendations and to assess the rate of bacterial meningitis detected among these children...
  18. ncbi Post-dural puncture headache: pathogenesis, prevention and treatment
    D K Turnbull
    Academic Anaesthetic Unit, University of Sheffield, K Floor, Royal Hallamshire Hospital, Sheffield, UK
    Br J Anaesth 91:718-29. 2003
    ....
  19. ncbi Aneurysmal subarachnoid hemorrhage: update for emergency physicians
    Jonathan A Edlow
    Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    J Emerg Med 34:237-51. 2008
    ..Emergency physicians must be expert in the diagnosis and initial stabilization of patients with SAH. Treatment in a hospital with both neurosurgical and endovascular capability is becoming the norm...
  20. ncbi Intermittent lumbar puncture in rats: a novel method for the experimental study of opioid tolerance
    Jijun J Xu
    Department of Anesthesiology and Molecular Genetics, Program in Genes and Development, Graduate School of Biomedical Sciences, University of Texas, M D Anderson Cancer Center, Houston, TX 77030, USA
    Anesth Analg 103:714-20. 2006
    ..Intermittent lumbar puncture should prove to be a useful technique for investigating mechanisms of spinal opioid analgesia and opioid tolerance development...
  21. pmc The role of lumbar puncture in children with suspected central nervous system infection
    Rachel Kneen
    The Roald Dahl EEG Unit, Royal Liverpool Children s NHS Trust, Alder Hey, Liverpool, L12 2AP, UK
    BMC Pediatr 2:8. 2002
    ..The use of the lumbar puncture in the diagnosis of central nervous system infection in acutely ill children is controversial. Recommendations have been published but it is unclear whether they are being followed...
  22. ncbi Addendum to assessment: Prevention of post-lumbar puncture headaches: report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology
    Carmel Armon
    Division of Neurology, Baystate Medical Center, Springfield, USA
    Neurology 65:510-2. 2005
    ..It affirmed a previous conclusion that smaller needle size is associated with reduced frequency of PLPHA (Level A recommendation)...
  23. ncbi Neonatal meningitis: what is the correlation among cerebrospinal fluid cultures, blood cultures, and cerebrospinal fluid parameters?
    Harmony P Garges
    Pediatrics, Duke University, Durham, North Carolina, USA
    Pediatrics 117:1094-100. 2006
    ..Abnormal cerebrospinal fluid (CSF) parameters are often used to predict neonatal meningitis and determine length and type of antibiotic therapy in neonates with a positive blood culture and negative CSF culture...
  24. ncbi Spinal delivery of analgesics in experimental models of pain and analgesia
    Carolyn A Fairbanks
    College of Pharmacy, University of Minnesota, Minneapolis, MN 55455, USA
    Adv Drug Deliv Rev 55:1007-41. 2003
    ..This review describes the pre-clinical models that enable new target discovery and development of novel analgesics for site-directed pain management...
  25. ncbi Determining the sensitivity of computed tomography scanning in early detection of subarachnoid hemorrhage
    Søren Cortnum
    Department of Neurosurgery, Aalborg Hospital, Aarhus UniversityHospital, 9000 Aalborg, Denmark
    Neurosurgery 66:900-2; discussion 903. 2010
    ..This study aims to determine the sensitivity of modern computed tomography (CT) scanners in detecting subarachnoid hemorrhage (SAH) and to determine whether there is a continued need for lumbar puncture to exclude the diagnosis...
  26. pmc Sensory neuron targeting by self-complementary AAV8 via lumbar puncture for chronic pain
    Benjamin Storek
    Department of Medicine and Neuroscience, Mount Sinai School of Medicine, New York, NY 10029, USA
    Proc Natl Acad Sci U S A 105:1055-60. 2008
    ..Therefore, gene transfer by LP may be suitable for developing gene therapy-based treatments for chronic pain...
  27. ncbi Sensitivity of noncontrast cranial computed tomography for the emergency department diagnosis of subarachnoid hemorrhage
    Richard L Byyny
    Department of Emergency Medicine, Denver Health Medical Center, Denver, CO, USA
    Ann Emerg Med 51:697-703. 2008
    ..The purpose of this study is to determine the sensitivity of noncontrast cranial CT in detecting all spontaneous subarachnoid hemorrhages and those caused by aneurysm or arteriovenous malformation...
  28. pmc Should a neonate with possible late onset infection always have a lumbar puncture?
    K Malbon
    Neonatal Unit, Northwick Park Hospital, Harrow HA1 3UJ, UK
    Arch Dis Child 91:75-6. 2006
  29. ncbi Indicators of acute bacterial meningitis in children at a rural Kenyan district hospital
    James A Berkley
    Centre for Geographic Medicine Research Coast, Kilifi, Kenya
    Pediatrics 114:e713-9. 2004
    ....
  30. ncbi Lumbar puncture delivery of bone marrow stromal cells in spinal cord contusion: a novel method for minimally invasive cell transplantation
    Ajay Bakshi
    Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, Pennsylvania 19129, USA
    J Neurotrauma 23:55-65. 2006
    ..The techniques described here can easily be translated to patients, thus accelerating clinical application of stem cell therapies...
  31. ncbi Septicemic neonates without lumbar puncture: what are we missing?
    Md Mahbubul Hoque
    Department of Neonatology, Dhaka Shishu Children s Hospital, Bangladesh Institute of Child Health, Dhaka, Bangladesh
    J Trop Pediatr 52:63-5. 2006
    ..5% vs. 13.3%), indicating the need for early diagnosis of this disease. Our data confirmed that it is important to do a lumbar puncture, along with blood culture, for all suspected septicemia cases...
  32. ncbi Risk factors for traumatic or unsuccessful lumbar punctures in children
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital and Harvard Medical School, Boston, MA 02115, USA
    Ann Emerg Med 49:762-71. 2007
    ..We sought to determine patient, physician, and procedural factors associated with traumatic and unsuccessful lumbar punctures in children...
  33. ncbi [Standards, options and recommendations for the management of procedure-related pain (lumbar puncture, bone marrow aspiration or biopsy, blood sampling) in children patients with cancer (summary report)]
    Claudine Schmitt
    Hôpital d Enfants, Nancy
    Bull Cancer 93:805-11. 2006
    ..The methodology is based on a literature review and critical appraisal by a multidisciplinary group of experts, with feedback from specialists in cancer care delivery...
  34. pmc The role of lumbar puncture in suspected CNS infection--a disappearing skill?
    R Kneen
    The Roald Dahl EEG Unit, Department of Neurology, Royal Liverpool Children s Hospital Alder Hey, Liverpool L12 2AP, UK
    Arch Dis Child 87:181-3. 2002
  35. ncbi Lumbar puncture success rate is not influenced by family-member presence
    Lise E Nigrovic
    Division of Emergency Medicine, Children s Hospital Boston and Harvard Medical School, Boston, MA 02115, USA
    Pediatrics 120:e777-82. 2007
    ..However, family presence might also affect clinicians' stress and anxiety, with uncertain consequences for procedural success...
  36. ncbi Psychological preparation for pediatric oncology patients undergoing painful procedures: a methodological critique of the research
    R N Rape
    Department of Psychology, University of Dayton, OH 45469
    Child Health Care 23:51-67. 1994
    ..g., self-efficacy) are modified by preparation is unclear. Following an overview of empirical investigations, we make recommendations for addressing these limitations in future research...
  37. ncbi Risk factors for traumatic and bloody lumbar puncture in children with acute lymphoblastic leukemia
    Scott C Howard
    Department of Hematology Oncology, St Jude Children s Research Hospital, Memphis, TN, USA
    JAMA 288:2001-7. 2002
    ..Traumatic or bloody lumbar puncture (LP) reduces the diagnostic value of the procedure and may worsen the outcome of patients with acute lymphoblastic leukemia (ALL). Little is known about the risk factors for traumatic and bloody LP...
  38. ncbi The management of infants and children treated with aciclovir for suspected viral encephalitis
    Rachel Kneen
    Department of Neurology, Littlewood s Neuroscience Unit, Alder Hey Children s NHS Foundation Trust, Liverpool, UK
    Arch Dis Child 95:100-6. 2010
    ..To investigate how infants and children with suspected viral encephalitis are currently managed in a UK tertiary children's hospital...
  39. ncbi Acute headache and subarachnoid haemorrhage: a retrospective review of CT and lumbar puncture findings
    J O'NEILL
    Department Clinical Radiology, Royal Infirmary Edinburgh
    Scott Med J 50:151-3. 2005
    ....
  40. ncbi Diagnosis of subarachnoid haemorrhage following a negative computed tomography for acute headache: a Bayesian analysis
    Timothy J Coats
    Emergency Medicine, Leicester University, Leicester Royal Infirmary, Leicester, UK
    Eur J Emerg Med 13:80-3. 2006
    ..We asked how many lumbar punctures need to be performed to detect each subarachnoid haemorrhage in these lower-risk patients...
  41. ncbi Raised intracranial pressure in acute viral encephalitis
    Gyanendra Kumar
    Department of Neurology, University of Missouri Healthcare Columbia, Columbia, MO, USA
    Clin Neurol Neurosurg 111:399-406. 2009
    ....
  42. ncbi Iatrogenic spinal epidermoid tumor. A complication of spinal puncture in an adult
    Jung Cheol Park
    Department of Neurosurgery, Seoul National University College of Medicine, 28 Yoengeon dong, Jongno gu, 110 744, Seoul, South Korea
    Clin Neurol Neurosurg 105:281-5. 2003
    ..The majority of epidermoid tumors reported are late complications of spinal puncture during the early neonatal period...
  43. ncbi Post-dural puncture headache: part I diagnosis, epidemiology, etiology, and pathophysiology
    David Bezov
    Montefiore Hospital Neurology, New York, NY, USA
    Headache 50:1144-52. 2010
    ..In this review, we will highlight diagnosis and clinical characteristics of PDPH, differential diagnosis, frequency, and risk factors as well as pathophysiology of PDPH...
  44. ncbi [Multicenter study on lumbar puncture indication, clinical practice and feasibility]
    C Paquet
    CMRR Paris Nord Île de France, groupe hospitalier Lariboisière Fernand Widal Saint Louis, AP HP, Universite Denis Diderot, 2 rue Ambroise Pare, Paris, France
    Rev Neurol (Paris) 168:28-32. 2012
    ..The aims of this study were firstly to compare the LP procedure and CSF transport process in all French Memory Centers and secondly to evaluate the incidence of LP side effects in 100 patients with cognitive disturbances...
  45. ncbi Sterile cerebrospinal fluid pleocytosis in young febrile infants with urinary tract infections
    David Schnadower
    Division of Pediatric Emergency Medicine, Washington University in St Louis School of Medicine, 660 S Euclid Ave, PO Box 8116, St Louis, MO 63110, USA
    Arch Pediatr Adolesc Med 165:635-41. 2011
    ....
  46. ncbi How valuable is a lumbar puncture in the management of patients with suspected subarachnoid haemorrhage?
    C Foot
    Emergency Department, Princess Alexandra Hospital, Brisbane, Queensland, Australia
    Emerg Med (Fremantle) 13:326-32. 2001
    ....
  47. ncbi Subarachnoid haemorrhage: diagnosis, causes and management
    J van Gijn
    Department of Neurology, University Medical Centre, Utrecht, The Netherlands
    Brain 124:249-78. 2001
    ..Once ischaemia has occurred, treatment regimens such as a combination of induced hypertension and hypervolaemia, or transluminal angioplasty, are plausible, but of unproven benefit...
  48. ncbi Lumbar puncture in children from an area of malaria endemicity who present with a febrile seizure
    Moses Laman
    Papua New Guinea Institute of Medical Research, Modilon General Hospital, Madang, Papua New Guinea
    Clin Infect Dis 51:534-40. 2010
    ..Our primary hypothesis was that children who present with a single seizure but with no clinical signs of meningism or coma do not require LP as part of initial diagnostic assessment...
  49. ncbi Vascular parkinsonism: clinical correlates predicting motor improvement after lumbar puncture
    William G Ondo
    Baylor College of Medicine, Department of Neurology, Houston, Texas, USA
    Mov Disord 17:91-7. 2002
    ..These results warrant further investigation and also raise the possibility of testing CSF drainage in patients with idiopathic PD complicated by SCWMC...
  50. pmc Is lumbar puncture necessary for evaluation of early neonatal sepsis?
    B Ray
    Paediatrics, Northern Deanery, Newcastle upon Tyne, UK
    Arch Dis Child 91:1033-5. 2006
  51. ncbi Does lumbar cerebrospinal fluid reflect ventricular cerebrospinal fluid? A prospective study in patients with external ventricular drainage
    Jan B Sommer
    Department of Neurology, University of Erlangen Nurnberg, Erlangen, Germany
    Eur Neurol 47:224-32. 2002
    ....
  52. pmc Diagnostic lumbar puncture. Comparative study between 22-gauge pencil point and sharp bevel needle
    Liisa Luostarinen
    Department of Neurology, Paijat Hame Central Hospital, Keskussairaalankatu 7, FIN 15850 Lahti, Finland
    J Headache Pain 6:400-4. 2005
    ..Seeking help for this condition was insufficient and only part of these PDPH patients were treated with epidural blood patch...
  53. ncbi Post-dural puncture headache and other complications after lumbar puncture
    C Chordas
    Baylor College of Medicine, Texas Children's Cancer Center, Houston, TX, USA
    J Pediatr Oncol Nurs 18:244-59. 2001
    ..As such, implications for the role of nursing are essential before, during, and after a lumbar puncture and are briefly discussed...
  54. ncbi Low incidence of post-lumbar puncture headache in 1,089 consecutive memory clinic patients
    Henrik Zetterberg
    Institute of Neuroscience and Physiology, Department of Psychiatry and Neurochemistry, The Sahlgrenska Academy at the University of Gothenburg, Molndal, Sweden
    Eur Neurol 63:326-30. 2010
    ..To examine the incidence of post-lumbar puncture headache (PLPH) in patients admitted for cognitive disturbances...
  55. ncbi "Atraumatic" Sprotte needle reduces the incidence of post-lumbar puncture headaches
    M Strupp
    Department of Neurology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Neurology 57:2310-2. 2001
    ..4% of patients in the "traumatic" group developed PLPH, whereas only 12.2% of patients in the "atraumatic" group did (p < 0.05). Therefore, use of the "atraumatic" Sprotte needle for lumbar puncture is recommended...
  56. ncbi Diagnosis of subarachnoid hemorrhage
    Jonathan A Edlow
    Department of Emergency Medicine, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, MA, USA
    Neurocrit Care 2:99-109. 2005
    ..Other diagnostic issues are also discussed, such as use of magnetic resonance scanning and angiography for diagnosis, distinguishing the traumatic LP from true SAH, the concept of warning bleeds, and the LP-first diagnostic strategy...
  57. ncbi Epidural blood patch reduces the incidence of post lumbar puncture headache
    W Heide
    Department of Neurology, University of Essen, Federal Republic of Germany
    Headache 30:280-1. 1990
    ..We conclude that the epidural blood patch is practicable and effective in the prophylaxis of postpuncture headache, but cannot prevent its occurrence in all cases...
  58. ncbi Mechanisms behind postspinal headache and brain stem compression following lumbar dural puncture--a physiological approach
    P O Grande
    Department of Anesthesia and Intensive Care, University and University Hospital of Lund, SE 221 85 Lund, Sweden
    Acta Anaesthesiol Scand 49:619-26. 2005
    ..The cause of postspinal headache and its specific characteristics are unknown, and whether lumbar dural puncture (LP) triggers brain-stem compression in patients with brain oedema is still controversial...
  59. ncbi A 5-year-old girl with headache and eye pain
    Robert Listernick
    Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
    Pediatr Ann 37:9-12. 2008
  60. ncbi The lumbar puncture in pediatric oncology
    P Coccia
    Division of Pediatric Oncology, Policlinico A Gemelli, Catholic University of Rome
    Pediatr Med Chir 28:73-8. 2006
    ..Lumbar puncture is generally well tolerated but might be characterized by several disadvantages and risks...
  61. ncbi Non-surgical management of intracranial subdural hematoma complicating spinal anesthesia
    M T Verdu
    Hospital Universitario Virgen de la Arrixaca, Murcia, Spain
    Neurocirugia (Astur) 18:40-3. 2007
    ..In the present case the subdural hemorrhage was detected at our hospital 20 days after the anesthetic procedure, and given the excellent state of consciousness, we choosed a conservative management...
  62. ncbi [Acute and chronic headaches]
    Anne Ducros
    Urgences Cephalees, Hopital Lariboisiere, 75010 Paris
    Rev Prat 56:2161-72. 2006
  63. ncbi [Post-lumbar puncture headache]
    Antonio Monteiro Rodriques
    Service d accueil et traitement des urgences, Centre Hospitalier Universitaire, Angers Cedex
    Rev Prat 57:353-7. 2007
    ..Prevention is based on using small-gauge pencil-point needles whereas the duration of bed rest has no effect on the incidence of postlumbar puncture headache...
  64. ncbi Aneurysmal subarachnoid leak with normal CT and CSF spectrophotometry
    Mark O McCarron
    Department of Neurology, Altnagelvin Hospital, Londonderry, BT47 6SB, UK
    Neurology 64:923. 2005
  65. ncbi Prevention and management of post-lumbar puncture headache in pediatric oncology patients
    Livia Chi Yan Lee
    Intermediate Care Unit, Inova Fairfax Hospital, Fairfax, VA, USA
    J Pediatr Oncol Nurs 24:200-7. 2007
    ....
  66. ncbi [Intracranial hypotension with subdural hematoma following lumbar puncture: case report]
    S Trunet
    Service de Neurochirurgie, Hopital Maison Blanche, 45, rue Cognacq Jay, 51092 Reims, France
    Neurochirurgie 54:85-8. 2008
    ..Lumbar puncture is a common procedure highly contributive to neurological diagnosis. It can also cause serious adverse side effects including subdural hematoma and intracranial hypotension as illustrated by this case report...
  67. ncbi Post-dural puncture arm and upper back pain--a report of two cases
    Ching Tzu Ho
    Division of Anesthesiology, Armed Forces Taoyuan General Hospital, Taoyuan, Taiwan, ROC
    Acta Anaesthesiol Taiwan 43:123-6. 2005
    ..We report two cases who sustained arm and upper back pain after spinal anesthesia, and epidural blood patch gave them a complete relief of the symptoms...
  68. ncbi Inhaled corticosteroids, adrenal suppression and benign intracranial hypertension
    Patrick Patradoon-Ho
    Blacktown Mt Druitt Health, Sydney West Area Health Service, NSW, Australia
    Med J Aust 185:279-80. 2006
  69. ncbi Hearing loss and cerebrospinal fluid pressure: case report and review of the literature
    Matthew S Pogodzinski
    Department of Otorhinolaryngology, Mayo Clinic, Rochester, MN 55905, USA
    Ear Nose Throat J 87:144-7. 2008
    ..We treated him with a standard epidural blood patch. Immediately after treatment, his hearing improved and his headache resolved...
  70. ncbi Aneurysmal rebleeding episode after lumbar puncture
    Ying Sheng Shen
    Department of Emergency Medicine, Cathay General Hospital, Taipei, Taiwan, Republic of China
    Am J Emerg Med 25:984.e1-3. 2007
  71. doi "Low-pressure" headache in intracranial hypertension
    Chad Whyte
    Headache 48:642-3. 2008
  72. ncbi High incidence of post-lumbar puncture headaches in patients with multiple sclerosis treated with natalizumab: role of intrathecal leukocytes
    Olaf Stuve
    Arch Neurol 64:1055-6. 2007
  73. ncbi [Headache due to low CSF pressure--not only after lumbar puncture]
    A Straube
    Neurologische Klinik, Klinikum Grosshadern, Munchen
    MMW Fortschr Med 147:51-2. 2005
  74. ncbi The treatment and prevention of post-dural puncture headache
    K M Kuczkowski
    Acta Anaesthesiol Belg 57:55-6. 2006
  75. ncbi Post dural puncture headache in a pediatric patient with idiopathic intracranial hypertension
    Olubukola O Nafiu
    Department of Anesthesiology, University of Michigan, Ann Arbor, MI 48109 0048, USA
    Paediatr Anaesth 15:778-81. 2005
    ..This is the first report of PPDH and its successful management with an epidural blood patch in a pediatric patient with IIH...
  76. ncbi Beyond spinal headache: prophylaxis and treatment of low-pressure headache syndromes
    Wendy I Warwick
    Department of Anesthesiology, Virginia Mason Medical Center, Seattle, WA, USA
    Reg Anesth Pain Med 32:455-61. 2007
    ..This Evidence-Based Case Management article evaluates and grades the evidence for two anesthesiology-related interventions: prophylaxis after unintentional meningeal puncture and treatment of spontaneous intracranial hypotension (SIH)...
  77. ncbi Attitudes and judgment of emergency physicians in the management of patients with acute headache
    Jeffrey J Perry
    Department of Emergency Medicine, University of Ottawa, Ontario, Canada
    Acad Emerg Med 12:33-7. 2005
    ....
  78. ncbi An MRI study of lumbar puncture headaches
    J Iqbal
    Neurology Service, Veterans Affairs Medical Center, Albuquerque, NM, USA
    Headache 35:420-2. 1995
    ..The study demonstrates that cerebrospinal fluid usually leaks into the paraspinous area after a lumbar puncture, but the volume of escaped fluid does not correlate with a lumbar puncture headache...
  79. ncbi Diagnosis of subarachnoid hemorrhage in the emergency department
    Jonathan A Edlow
    Department of Medicine, Harvard Medical School, Beth Israel Deaconess Medical Center, 1 Deaconess Road CC 205, Boston, MA 02215, USA
    Emerg Med Clin North Am 21:73-87. 2003
    ..In addition, the CSF should be carefully analyzed, including measuring the opening pressure. In patients whose CT scans and CSF analyses are normal, further testing is rarely indicated...
  80. ncbi Cerebral angiographic findings of spontaneous intracranial hypotension
    John D Roll
    Department of Radiology, Vanderbilt University Medical Center, Nashville, TN, USA
    AJNR Am J Neuroradiol 24:707-8. 2003
    ..In situations in which the typical clinical presentation is not present and additional examinations such as cerebral angiography are performed, these findings may be helpful to direct the physicians involved toward the correct diagnosis...
  81. ncbi Postdural puncture headache in children
    S Lewis
    Paediatr Anaesth 13:367-8; author reply 368-9. 2003
  82. ncbi [Contrast uptake after spinal tap: myth or reality?]
    F Laigle-Donadey
    Rev Neurol (Paris) 159:586. 2003
  83. ncbi Post-dural puncture headache, intracranial air and obstetric anesthesia
    K M Kuczkowski
    Departments of Anesthesiology and Reproductive Medicine, University of California San Diego, California 92103, USA
    Anaesthesist 52:798-800. 2003
    ..This case report raises one more time the question about the safety of the LORA technique for labor analgesia...
  84. ncbi The management of a postdural puncture headache in a child
    Andrew Liley
    Birmingham Childrens Hospital, Steelhouse Lane, Birmingham, UK
    Paediatr Anaesth 13:534-7. 2003
    ..An epidural blood patch was performed with immediate and complete resolution of her symptoms. We present this case to highlight the occurrence of PDPH in children and to outline the considerations for management...
  85. ncbi Once a post-dural puncture headache patient always post-dural puncture headache patient?
    K M Kuczkowski
    Department of Anesthesiology, UCSD Medical Center, 200 West Arbor Drive, San Diego, CA 92103 8770, USA
    Acta Anaesthesiol Belg 54:167-8. 2003
    ..It is well known that symptoms of post-dural puncture headache (PDPH) are more likely if there has been a preceding PDPH. We herein present a patient who developed a PDPH following each of two dural punctures separated by 9 years...
  86. ncbi Post-dural puncture headache: pathophysiology, prevention and treatment
    Kenneth D Candido
    Department of Anesthesiology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
    Best Pract Res Clin Anaesthesiol 17:451-69. 2003
    ..The optimum volume of blood has been shown to be 12-20 ml for adult patients. Complications of autologous epidural blood patch are rare...
  87. ncbi Superior sagittal sinus thrombosis in a patient with postdural puncture headache
    Honorio T Benzon
    Department of Anesthesiology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
    Reg Anesth Pain Med 28:64-7. 2003
    ..We present a patient who had a superior sagittal sinus thrombosis in addition to his PDPH. The signs and symptoms of intracranial pathology in patients with dural puncture headache, in addition to their postural headache, are discussed...
  88. ncbi Practice parameter: evaluation of children and adolescents with recurrent headaches: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society
    D W Lewis
    Department of Pediatrics, Children s Hospital of the King s Daughters, Eastern Virginia Medical School, Norfolk, VA, USA
    Neurology 59:490-8. 2002
    ..For this parameter, the authors reviewed available evidence on the evaluation of the child with recurrent headaches and made recommendations based on this evidence...
  89. ncbi Education of referring doctors about sudden onset headache in subarachnoid hemorrhage. A prospective study
    S Fridriksson
    Departments of Neurosurgery and Neurology, University Hospital, , Sweden
    Acta Neurol Scand 103:238-42. 2001
    ..Teaching programs focused on local physicians have a profound impact on outcome at low cost...
  90. ncbi [The visualisation of dura perforation and blood patches with ultrasound]
    T Grau
    Abteilung für Anästhesiologie, Universitatsklinikum Heidelberg, Germany
    Anasthesiol Intensivmed Notfallmed Schmerzther 37:149-53. 2002
    ..Since these informations are relevant for further clinical practice further investigations are warranted...
  91. ncbi Life-threatening intracranial hypotension after diagnostic lumbar puncture
    A Francia
    Third Clinic of Neurology, Department of Neurological Sciences, La Sapienza University, Rome, Italy
    Neurol Sci 22:385-9. 2001
    ..We stress the need for epidural blood patch in any case of post-diagnostic lumbar puncture postural headache which does not resolve with conservative therapy...
  92. ncbi [Magnetic resonance in dural post-puncture headache in patient with cerebrospinal fluid hypotension]
    M A Reina
    Servicio de Anestesiología del Hospital de Móstoles, y Hospital Madrid Montepríncipe, Madrid
    Rev Esp Anestesiol Reanim 49:89-100. 2002
    ..MRI allows the degree of cerebral and spinal involvement to be ascertained, to predict whether resolution of the clinical picture will be early or late and to visualize the effect of approaches to reducing CSF leakage...
  93. ncbi Epidural blood patch for management of postdural puncture headache in adolescents
    P Ylönen
    Department of Anesthesiology and Intensive Care, Kuopio University Hospital, Finland
    Acta Anaesthesiol Scand 46:794-8. 2002
    In some patients spinal puncture (SP) is followed by postdural puncture headache (PDPH). When the symptoms of PDPH are severe and are not relieved within a few days an epidural blood patch (EBP) might be performed...
  94. ncbi Dural punctures in children: what should we do?
    Alexander Oliver
    Paediatr Anaesth 12:473-7. 2002
  95. ncbi Management of postdural puncture headache with epidural blood patch in children
    Paula Ylönen
    Department of Anaesthesiology and Intensive Care, Kuopio University Hospital, Finland
    Paediatr Anaesth 12:526-9. 2002
    ..was an uncommon complaint in children, but recent studies indicate that young children may develop PDPH after spinal puncture. When the symptoms are severe and are not relieved within a few days with analgesics, forced hydration and ..
  96. ncbi Pneumocephalus as a cause for headache
    W J Becker
    University of Calgary and Calgary Health Region, Calgary, Alberta, Canada
    Can J Neurol Sci 29:278-81. 2002
    ..Pneumocephalus can be a cause of headache, but is easily overlooked in some clinical circumstances...
  97. ncbi Post-dural puncture headaches in children. A literature review
    Elke Janssens
    Department of Paediatrics, Catholic University of Leuven, Leuven, Belgium
    Eur J Pediatr 162:117-21. 2003
    ..Once the diagnosis is made, conservative therapy is recommended for 48 h. Persistent PDPH can be treated in several ways; an epidural blood patch is one of the most effective methods...
  98. ncbi Epidural blood patch placed in the presence of an unknown cervical epidural hematoma
    Daniel Castillo
    Department of Anesthesiology, Perioperative and Pain Medicine, Harvard Medical School, Brigham and Women s Hospital, Boston, Massachusetts 02115, USA
    Anesth Analg 97:885-7. 2003
    ....
  99. ncbi Post dural puncture headache in an anticoagulated patient
    H Bird
    Int J Obstet Anesth 13:59-61. 2004
  100. ncbi The diagnosis and treatment of a patient with puerperal infection and subdural hygromas
    Natàlia Aragonès
    Department of Anesthesia, Hospital Universitari Doctor Josep Trueta, Girona, Catalonia, Spain
    Anesth Analg 99:1218-20, table of contents. 2004
    ..The patient had signs of a puerperal infection, and an epidural patch was performed with dextran 40 instead of blood, after which gradual improvement was noted. The patient was discharged totally asymptomatic 3 days later...
  101. ncbi Post-dural puncture headache
    R Sharma
    Br J Anaesth 92:449; author reply 449-50. 2004

Research Grants28

  1. AIDS CLINICAL TRIALS
    Lisa Frenkel; Fiscal Year: 2002
    ..The PACTG site reports and regulatory evaluations of the UW PACTU which have generally been excellent are discussed. This proposal requests funds for the continuation of the successful UW PACTU. ..
  2. Improving informed consent in Alzheimer disease research
    Jason Karlawish; Fiscal Year: 2006
    ..The results will also begin to elucidate how experts make judgments of competency. [unreadable] [unreadable] [unreadable]..
  3. Reservoirs of drug-resistant HIV-1
    Lisa Frenkel; Fiscal Year: 2009
    ..These data assist in establishing complementary MTCT prophylaxis regimens and HAART for women and children. ..
  4. Intermittent Explosive Disorder: A Family Study
    EMIL COCCARO; Fiscal Year: 2005
    ..e., relatives of IED probands with and without IED). ..
  5. Social Information Processing: Assessment Development
    EMIL COCCARO; Fiscal Year: 2007
    ..Development of such measures is critical for the further scientific study of SIP and for its integration in neurobiologhical research. [unreadable] [unreadable]..
  6. Impulsive Aggression : A Twin Study of Behavior and 5-HT
    EMIL COCCARO; Fiscal Year: 2006
    ..abstract_text> ..
  7. Fluoxetine and Divalproex:Treatment Correlates in Intermittent Explosive Disorder
    EMIL COCCARO; Fiscal Year: 2007
    ..Duration of treatment will be twelve weeks. ..
  8. Outcome Measures in Idiopathic Intracranial Hypertension
    Deborah Friedman; Fiscal Year: 2008
    ..Acquire the training, mentoring and experience necessary to conduct independent, funded clinical research in ophthalmologic and neurological disorders Obtain a Masters Degree in Public Health/Clinical Investigator track ..
  9. ALZHEIMER'S IN LONG TERM PROPRANOLOL FOR AGITATION
    Elaine Peskind; Fiscal Year: 2003
    ..We will determine if high plasma NE and/or high lymphocyte beta-adrenergic receptor density, affinity, and/or sensitivity define AD patients with disruptive agitation most responsive to propranolol. ..
  10. Etiology of mastitis in HIV-1 infected women
    Lisa Frenkel; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  11. Androgen Hormones in PMDD
    Margaret Altemus; Fiscal Year: 2007
    ..This study will also provide evidence as to whether androgen hormones, acting through androgen receptors, play a role in the pathophysiology of PMDD. ..
  12. OPTIMIZING RADIOIMMUNOTHERAPY FOR NON HODGKIN'S LYMPHOMA
    Ajay Gopal; Fiscal Year: 2005
    ..We anticipate that these interventions will ultimately enhance the prognosis for patients with relapsed lymphoma by increasing the response and survival rates, while simultaneously minimizing toxicities. ..
  13. CRF and Personality Disorder: Behavioral Correlates
    Royce Lee; Fiscal Year: 2003
    ..abstract_text> ..
  14. BIOMECHANICS OF BRAIN EDEMA AND INTRACRANIAL PRESSURE
    Anthony Marmarou; Fiscal Year: 2007
    ..Taken in concert, these studies will provide a more indepth understanding of the role of aquaporins in brain injury and introduce novel therapeutic approaches for treating brain edema. ..
  15. Immunization by HIV exposure during chemoprophylaxis
    Lisa Frenkel; Fiscal Year: 2006
    ..In the absence of an effective vaccine, the use of antiretrovirals should be optimized to prevent the spread of HIV-1 infection. This proposal works toward this goal. ..
  16. Mechanism/predictors of genital/rectal HIV shedding during ART w/plasma <50c/mL
    Lisa M Frenkel; Fiscal Year: 2010
    ..A better understanding of this discordant genital tract and rectal shedding should allow us to develop better treatment strategies that should reduce HIV transmission. ..
  17. Proapoptotic Therapy for B-cell Non Hodgkin's Lymphoma
    Ajay Gopal; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  18. BRAIN PATHOPHYSIOLOGY IN ANXIETY DISORDERS
    GREGORY SULLIVAN; Fiscal Year: 2008
    ..Through such work, he seeks to contribute to the understanding of the pathophysiology of PD in order to suggest improved therapeutics for this devastating and underrecognized brain disorder. ..
  19. PEDIATRIC ONCOLOGY GROUP STUDIES
    Thomas McLean; Fiscal Year: 2002
    ....
  20. EFFECT OF SRIs ON GONADAL STEROIDS
    Margaret Altemus; Fiscal Year: 2006
    ..Currently, for the 30% of subjects with PMDD and OCD who do not respond to SRI treatment, there are few, if any, alternative pharmacologic strategies. ..
  21. THERAPY EFFECTS ON HIV 1 POPULATION DYNAMICS IN CHILDREN
    Lisa Frenkel; Fiscal Year: 2002
    ....
  22. ESTROGEN EFFECTS ON ANXIETY RELATED NEURAL SYSTEMS
    Margaret Altemus; Fiscal Year: 2004
    ..This field of investigation is likely to improve understanding and treatment of anxiety and affective disorders, both of which are widely prevalent, chronic public health problems. ..
  23. ROLE OF T PALLIDUM MSP-HOMOLOGUES IN CNS INVASION
    Christina Marra; Fiscal Year: 2004
    ..These investigations are most applicable to persons who are also infected with HIV-1, as they are at greatest risk for syphilis and neurosyphilis. ..
  24. Rapid and Simple CSF Tests for Neurosyphillis Diagnosis
    Christina Marra; Fiscal Year: 2006
    ..The results of this study will be used to design field trials in the areas of greatest need. ..
  25. COMMUNITY EQUIPOISE AND THE ETHICS OF CLINICAL RESEARCH
    Jason Karlawish; Fiscal Year: 2002
    ..Karlawish advanced training in bioethics scholarship. Other sponsors include experts in clinical trial design, Alzheimers Disease research and empirical research in research ethics. ..
  26. Consent Methods and Participation in Geriatric Clinical Research
    Jason Karlawish; Fiscal Year: 2009
    ..These results will assist researchers and proxies in conducting subject-centered informed consent discussions. ..
  27. Novel Methods to Access Brain Function in HIV-1
    Christina Marra; Fiscal Year: 2003
    ..abstract_text> ..