ultraviolet therapy

Summary

Summary: The use of ultraviolet electromagnetic radiation in the treatment of disease, usually of the skin. This is the part of the sun's spectrum that causes sunburn and tanning. Ultraviolet A, used in PUVA, is closer to visible light and less damaging than Ultraviolet B, which is ionizing.

Top Publications

  1. pmc Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques
    Leanne M Johnson-Huang
    Laboratory for Investigative Dermatology, Rockefeller University, New York, New York 10065, USA
    J Invest Dermatol 130:2654-63. 2010
  2. ncbi Management of guttate and generalized psoriasis vulgaris: prospective randomized study
    Nina G Caca-Biljanovska
    Department of Dermatology, Sts Cyrilus and Methodius University School of Medicine, Skopje, Republic of Macedonia
    Croat Med J 43:707-12. 2002
  3. ncbi A review of phototherapy protocols for psoriasis treatment
    Whitney Lapolla
    Center for Dermatology Research, Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1071, USA
    J Am Acad Dermatol 64:936-49. 2011
  4. pmc Ultraviolet C irradiation: an alternative antimicrobial approach to localized infections?
    Tianhong Dai
    Wellman Center for Photomedicine, Massachusetts General Hospital, 40 Blossom Street, Boston, MA 02114, USA
    Expert Rev Anti Infect Ther 10:185-95. 2012
  5. ncbi Antimicrobial efficacy of riboflavin/UVA combination (365 nm) in vitro for bacterial and fungal isolates: a potential new treatment for infectious keratitis
    Suy Anne R Martins
    Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Invest Ophthalmol Vis Sci 49:3402-8. 2008
  6. ncbi Narrowband UVB phototherapy for small plaque parapsoriasis
    K Aydogan
    Department of Dermatology, Uludag University Faculty of Medicine, Bursa, Turkey
    J Eur Acad Dermatol Venereol 20:573-7. 2006
  7. ncbi Treatments for psoriasis and the risk of malignancy
    Rita V Patel
    University of Miami Miller School of Medicine, Miami, Florida, USA
    J Am Acad Dermatol 60:1001-17. 2009
  8. ncbi No evidence for increased skin cancer risk in psoriasis patients treated with broadband or narrowband UVB phototherapy: a first retrospective study
    Maren Weischer
    Department of Dermatology, Eberhard Karls University, Tuebingen, Germany
    Acta Derm Venereol 84:370-4. 2004
  9. ncbi UVB phototherapy and skin cancer risk: a review of the literature
    Ernest Lee
    University of California, Department of Dermatology, Psoriasis Treatment Center, 515 Spruce Street, San Francisco, CA 94118, USA
    Int J Dermatol 44:355-60. 2005
  10. ncbi Ultraviolet A/riboflavin corneal cross-linking for infectious keratitis associated with corneal melts
    Hans Peter Iseli
    Institute of Refractive and Ophthalmic Surgery, Zurich, Switzerland
    Cornea 27:590-4. 2008

Detail Information

Publications190 found, 100 shown here

  1. pmc Effective narrow-band UVB radiation therapy suppresses the IL-23/IL-17 axis in normalized psoriasis plaques
    Leanne M Johnson-Huang
    Laboratory for Investigative Dermatology, Rockefeller University, New York, New York 10065, USA
    J Invest Dermatol 130:2654-63. 2010
    ..JID JOURNAL CLUB ARTICLE: For questions, answers, and open discussion about this article, please go to http://www.nature.com/jid/journalclub...
  2. ncbi Management of guttate and generalized psoriasis vulgaris: prospective randomized study
    Nina G Caca-Biljanovska
    Department of Dermatology, Sts Cyrilus and Methodius University School of Medicine, Skopje, Republic of Macedonia
    Croat Med J 43:707-12. 2002
    ....
  3. ncbi A review of phototherapy protocols for psoriasis treatment
    Whitney Lapolla
    Center for Dermatology Research, Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1071, USA
    J Am Acad Dermatol 64:936-49. 2011
    ..Ultraviolet light is an effective, relatively safe modality that is a valuable tool in the treatment of psoriasis. NB-UVB phototherapy is considered the first-line treatment for extensive plaque type psoriasis...
  4. pmc Ultraviolet C irradiation: an alternative antimicrobial approach to localized infections?
    Tianhong Dai
    Wellman Center for Photomedicine, Massachusetts General Hospital, 40 Blossom Street, Boston, MA 02114, USA
    Expert Rev Anti Infect Ther 10:185-95. 2012
    ..UVC should be used in a manner such that the side effects would be minimized and resistance of microorganisms to UVC would be avoided...
  5. ncbi Antimicrobial efficacy of riboflavin/UVA combination (365 nm) in vitro for bacterial and fungal isolates: a potential new treatment for infectious keratitis
    Suy Anne R Martins
    Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Invest Ophthalmol Vis Sci 49:3402-8. 2008
    ..To demonstrate the antimicrobial properties of riboflavin/UVA (365 nm) against common pathogens...
  6. ncbi Narrowband UVB phototherapy for small plaque parapsoriasis
    K Aydogan
    Department of Dermatology, Uludag University Faculty of Medicine, Bursa, Turkey
    J Eur Acad Dermatol Venereol 20:573-7. 2006
    ..Narrowband UVB (NB-UVB) phototherapy has been shown to be effective for the treatment of various dermatoses...
  7. ncbi Treatments for psoriasis and the risk of malignancy
    Rita V Patel
    University of Miami Miller School of Medicine, Miami, Florida, USA
    J Am Acad Dermatol 60:1001-17. 2009
    ..With the advent of these novel immunosuppressive therapies, one of the central safety issues surrounding these agents is their potential to increase the risk of malignancy...
  8. ncbi No evidence for increased skin cancer risk in psoriasis patients treated with broadband or narrowband UVB phototherapy: a first retrospective study
    Maren Weischer
    Department of Dermatology, Eberhard Karls University, Tuebingen, Germany
    Acta Derm Venereol 84:370-4. 2004
    ..The tumour occurred within the same year that phototherapy was initiated. Thus, the present study does not provide evidence for an increased skin cancer risk for patients treated with either broadband or narrowband UVB phototherapy..
  9. ncbi UVB phototherapy and skin cancer risk: a review of the literature
    Ernest Lee
    University of California, Department of Dermatology, Psoriasis Treatment Center, 515 Spruce Street, San Francisco, CA 94118, USA
    Int J Dermatol 44:355-60. 2005
    ..Over the past 20 years, numerous studies have been published examining this issue, but a consensus or analysis of the skin cancer risk is required for the dermatologist to make an educated risk-benefit analysis...
  10. ncbi Ultraviolet A/riboflavin corneal cross-linking for infectious keratitis associated with corneal melts
    Hans Peter Iseli
    Institute of Refractive and Ophthalmic Surgery, Zurich, Switzerland
    Cornea 27:590-4. 2008
    ..To evaluate the efficacy of ultraviolet-corneal cross-linking (CXL) for treating infectious melting keratitis...
  11. ncbi Monochromatic excimer light (308 nm): an immunohistochemical study of cutaneous T cells and apoptosis-related molecules in psoriasis
    B Bianchi
    Department of Dermatological Sciences, University of Florence, Via degli Alfani, 37, 50121 Florence, Italy
    J Eur Acad Dermatol Venereol 17:408-13. 2003
    ..Recently, a new UVB source generated by a 308-nm excimer laser has been introduced for the treatment of psoriasis...
  12. ncbi Ultraviolet A1 phototherapy
    R S Dawe
    Photobiology Unit, Department of Dermatology, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, UK
    Br J Dermatol 148:626-37. 2003
    ..However, much more research is needed to confirm its efficacy for many of its potential indications, and to determine when and how it should be used...
  13. ncbi Treatment of small plaque parapsoriasis with narrow-band (311 nm) ultraviolet B: a retrospective study
    T Herzinger
    Department of Dermatology, University of Munich, Germany
    Clin Exp Dermatol 30:379-81. 2005
    ..Therefore, NB-UVB is an effective, comparably safe and convenient alternative to psoralen and ultraviolet A therapy or other treatment modalities in the suppression of SPP...
  14. ncbi An intraindividual study of the characteristics of erythema induced by bath and oral methoxsalen photochemotherapy and narrowband ultraviolet B
    Irene Man
    Photobiology Unit, Department of Dermatology, Ninewells Hospital and Medical School, University of Dundee, Dundee, UK
    Photochem Photobiol 78:55-60. 2003
    ..019). The majority of subjects were at maximal erythema at 12 h (22 of 28) and 15 h (eight of nine). Our results suggest that peak erythema for bath PUVA, oral PUVA and TL-01 UVB occurs at 120, 96 and 12-15 h, respectively...
  15. pmc Light, including ultraviolet
    Emanual Maverakis
    Department of Dermatology, School of Medicine, University of California at Davis, Sacramento, CA 95816, USA
    J Autoimmun 34:J247-57. 2010
    ..Alternatively, photosensitizing molecules can damage cells by initiating sunburn-like phototoxic reactions. Herein we review all types of UV-induced skin reactions, especially those involving the immune system...
  16. ncbi Response of psoriasis to sunbed treatment: comparison of conventional ultraviolet A lamps with new higher ultraviolet B-emitting lamps
    S Das
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, U K
    Br J Dermatol 147:966-72. 2002
    ..A new fluorescent sunbed lamp has been developed that emits a higher proportion of UVB (4.6%) than conventional lamps and also requires shorter exposure times to achieve equivalent erythema...
  17. ncbi Ultraviolet B 308-nm excimer laser treatment of psoriasis: a new phototherapeutic approach
    W Gerber
    Department of Dermatology and Allergy, Klinikum Stadt Hanau, Leimenstrasse 20, 63450 Hanau, Germany
    Br J Dermatol 149:1250-8. 2003
    ..However, there has been no information available so far with regard to the cumulative dosage on a larger group of patients and on therapy optimized treatment strategies...
  18. ncbi Low-dose ultraviolet A1 phototherapy for extragenital lichen sclerosus: results of a preliminary study
    Alexander Kreuter
    Department of Dermatology and Allergology, Ruhr University Bochum, Germany
    J Am Acad Dermatol 46:251-5. 2002
    ....
  19. ncbi Collagen cross-linking: a new treatment paradigm in corneal disease - a review
    Grant R Snibson
    Centre for Eye Research Australia, Department of Ophthalmology, University of Melbourne, Royal Victorian Eye and Ear Hospital, East Melbourne, Victoria, Australia
    Clin Experiment Ophthalmol 38:141-53. 2010
    ..The aim of this review is to summarize the theoretical basis and risks of corneal collagen cross-linking, along with the available evidence for its use in keratoconus and other corneal disease states...
  20. ncbi Vitamin D serum level changes in psoriatic patients treated with narrowband ultraviolet B phototherapy are related to the season of the irradiation
    Aleksandra Lesiak
    Department of Dermatology, Medical University, Lodz, Poland
    Photodermatol Photoimmunol Photomed 27:304-10. 2011
    ..Vitamin D is produced in the human skin by short wavelength (290-315 nm) ultraviolet (UV) radiation...
  21. ncbi A randomized, observer-blinded trial of twice vs. three times weekly narrowband ultraviolet B phototherapy for chronic plaque psoriasis
    H Cameron
    Photobiology Unit, Department of Dermatology, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, U K
    Br J Dermatol 147:973-8. 2002
    ..The optimum treatment frequency for narrowband (TL-01) ultraviolet B (NB-UVB) in psoriasis is not yet known. We have previously found three times weekly to be preferable to five times weekly treatment in our population...
  22. ncbi Phototherapy in pediatric patients
    Aida Pasic
    Department of Dermatology and Venerology, Zagreb University Hospital Center, Zagreb, Croatia
    Pediatr Dermatol 20:71-7. 2003
    ..None of the patients exhibited any early phototherapy side effects. We conclude that phototherapy and PUVA bath are valuable and safe therapeutic options for selected children who do not respond to other treatments...
  23. ncbi Medium-dose 308-nm excimer laser for the treatment of psoriasis
    Manju Trehan
    Gange Photomedicine Research Center, Wellman Laboratories of Photomedicine, Department of Dermatology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    J Am Acad Dermatol 47:701-8. 2002
    ..The excimer laser delivers targeted ultraviolet B 308-nm radiation...
  24. ncbi Narrowband UVB phototherapy for early-stage mycosis fungoides: evaluation of clinical and histopathological changes
    G Gokdemir
    Dermatology Clinic, Sisli Etfal Research and Training Hospital, Istanbul, Turkey
    J Eur Acad Dermatol Venereol 20:804-9. 2006
    ..However, each of these modalities is associated with various side-effects. Narrowband UVB (NB-UVB) therapy has the same effect but is safer to use than the other methods...
  25. ncbi Narrow-band ultraviolet therapy in early-stage mycosis fungoides: study on 20 patients
    V Brazzelli
    Department of Human and Hereditary Pathology, Institute of Dermatology, University of Pavia, Fondazione IRCCS Policlinico S Matteo, Pavia, Italy
    Photodermatol Photoimmunol Photomed 23:229-33. 2007
    ..In recent years, narrow-band ultraviolet B (NB-UVB, 311-313 nm) has been found to be beneficial for early-stages mycosis fungoides (MF). The aim of this study is to investigate the effect of NB-UVB in 20 patients with early-stage MF...
  26. ncbi Photoactivation of DNA thiobases as a potential novel therapeutic option
    A Massey
    Imperial Cancer Research Fund, Clare Hall Laboratories, South Mimms, EN6 3LD, Herts, United Kingdom
    Curr Biol 11:1142-6. 2001
    ..Thiobase/UVA treatment may offer a novel therapeutic approach for the clinical management of nonmalignant conditions like psoriasis or for superficial tumors that are accessible to phototherapy...
  27. ncbi Clinical efficacy of narrow-band UVB (311 nm) combined with dithranol in psoriasis. An open pilot study
    P Carrozza
    Department of Dermatology, University Hospital Zurich, Switzerland
    Dermatology 200:35-9. 2000
    ..For UVB, the most effective wavelength in clearing psoriatic lesions was found to be of 313 nm. The efficacy of whole body exposure to narrow-band UVB (311 nm) combined with dithranol in psoriasis has not been evaluated to date...
  28. ncbi Narrowband UV-B phototherapy vs photochemotherapy in the treatment of chronic plaque-type psoriasis: a paired comparison study
    A Tanew
    Department of Dermatology, University of Vienna Medical School, Austria
    Arch Dermatol 135:519-24. 1999
    ..To compare the therapeutic efficacy of narrowband (TL-01) UV-B phototherapy vs photochemotherapy (psoralen-UV-A [PUVA]) in patients with chronic plaque-type psoriasis...
  29. ncbi Traditional therapies in the management of moderate to severe chronic plaque psoriasis: an assessment of the benefits and risks
    L Naldi
    Clinica Dermatologica, Ospedali Riuniti, Largo Barozzi, 1 24128 Bergamo, Italy
    Br J Dermatol 152:597-615. 2005
    ..This review summarizes the benefits and risks of traditional, nonbiological therapies for moderate to severe chronic plaque psoriasis...
  30. doi Home narrowband UV-B phototherapy in combination with low-dose acitretin in patients with moderate to severe psoriasis
    Christopher B Yelverton
    Arch Dermatol 144:1224-5. 2008
  31. ncbi Home ultraviolet B phototherapy for psoriasis: discrepancy between literature, guidelines, general opinions and actual use. Results of a literature review, a web search, and a questionnaire among dermatologists
    M B G Koek
    Department of Dermatology Allergology G 02 124, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    Br J Dermatol 154:701-11. 2006
    ..It is currently being prescribed for patients with psoriasis, although literature on the subject is scarce. Despite the apparent contradiction between clinical practice and literature, no systematic study of either has been conducted...
  32. ncbi [Therapeutic cross-linking of the cornea using riboflavin/UVA]
    T Koller
    Institut für Refraktive und Ophthalmologische Chirurgie, Zurich
    Klin Monbl Augenheilkd 224:700-6. 2007
    ..The method of cross-linking of the cornea using riboflavin and ultraviolet light (UV) has recently entered the phase of clinical evaluation. The purpose of this paper is to review the current knowledge about corneal cross-linking...
  33. ncbi Taking treatment to the patient: development of a home TL-01 ultraviolet B phototherapy service
    H Cameron
    Photobiology Unit, Department of Dermatology, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, U K
    Br J Dermatol 147:957-65. 2002
    ..While most patients requiring phototherapy can attend for hospital-based out-patient ultraviolet (UV) B therapy, a significant number cannot attend because of geographical, work, economic and other reasons...
  34. ncbi Light therapy (with UVA-1) for SLE patients: is it a good or bad idea?
    S Pavel
    Rheumatology (Oxford) 45:653-5. 2006
  35. ncbi Saline spa water or combined water and UV-B for psoriasis vs conventional UV-B: lessons from the Salies de Béarn randomized study
    C Leaute-Labreze
    Service de Dermatologie, Hôpital Saint André, 1 rue Jean Burguet, 33075 Bordeaux cedex, France
    Arch Dermatol 137:1035-9. 2001
    ..To study the effects of UV-B therapy and saline spa water given alone or in combination for the treatment of psoriasis...
  36. pmc UVB phototherapy in an outpatient setting or at home: a pragmatic randomised single-blind trial designed to settle the discussion. The PLUTO study
    Mayke B G Koek
    Department of Dermatology Allergology G02 124, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    BMC Med Res Methodol 6:39. 2006
    ..Thus, firm evidence to support or discourage the use of home UVB phototherapy has not yet been obtained. This is the goal of the present study, the PLUTO study (Dutch acronym for "national trial on home UVB phototherapy for psoriasis")...
  37. pmc Home versus outpatient ultraviolet B phototherapy for mild to severe psoriasis: pragmatic multicentre randomised controlled non-inferiority trial (PLUTO study)
    Mayke B G Koek
    Department of Dermatology Allergology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, Netherlands
    BMJ 338:b1542. 2009
    ..To determine whether ultraviolet B phototherapy at home is equally safe and equally effective as ultraviolet B phototherapy in an outpatient setting for patients with psoriasis...
  38. ncbi Adherence to acitretin and home narrowband ultraviolet B phototherapy in patients with psoriasis
    Brad A Yentzer
    Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1071, USA
    J Am Acad Dermatol 59:577-81. 2008
    ..However, few data exist about adherence rates to home phototherapy, adding to concerns about the appropriateness of home phototherapy as a psoriasis treatment option...
  39. ncbi An update and guidance on narrowband ultraviolet B phototherapy: a British Photodermatology Group Workshop Report
    S H Ibbotson
    Pathobiology Unit, Ninewells Hospital and Medical School, Dundee, UK
    Br J Dermatol 151:283-97. 2004
    ....
  40. ncbi Suggested mechanisms of action of UVA phototherapy in morphea: a molecular study
    M El-Mofty
    Department of Dermatology, Phototherapy Unit, Faculty of Medicine, Cairo University, Egypt
    Photodermatol Photoimmunol Photomed 20:93-100. 2004
    ..Ultraviolet A (UVA) phototherapy proved to be an efficient line of treatment of scleroderma. The mechanism through which it acts is still not clear...
  41. ncbi Efficacy of UVA-1 cold light as an adjuvant therapy for systemic lupus erythematosus
    M C A Polderman
    Department of Dermatology, B1 Q, Leiden University Medical Centre, PO Box 9600, NL 2300 RC, The Netherlands
    Rheumatology (Oxford) 43:1402-4. 2004
    ..The assessment of the efficacy of therapy of patients with moderately active systemic lupus erythematosus (SLE) with low doses of UVA-1 cold light...
  42. ncbi Cutaneous expression of cytochrome P450 CYP2S1: individuality in regulation by therapeutic agents for psoriasis and other skin diseases
    Gillian Smith
    Biomedical Research Centre, Ninewells Hospital and Medical School, DD1 9SY, Dundee, UK
    Lancet 361:1336-43. 2003
    ....
  43. ncbi Comparison of the 308-nm excimer laser and a 308-nm excimer lamp with 311-nm narrowband ultraviolet B in the treatment of psoriasis
    K Köllner
    Department of Dermatology, University of Regensburg, Franz Josef Strauss Allee 11, 93043 Regensburg, Germany
    Br J Dermatol 152:750-4. 2005
    ..Narrowband UVB (311 nm) phototherapy is a well-established, widely used and highly efficient treatment for psoriasis, but a big disadvantage is that large areas of unaffected skin are irradiated along with the psoriatic lesions...
  44. ncbi Pharmacoeconomic evaluation of calcipotriol (Daivonex/Dovonex) and UVB phototherapy in the treatment of psoriasis: a Markov model for The Netherlands
    M A De Rie
    Academisch Medisch Centrum, Amsterdam, The Netherlands
    Dermatology 202:38-43. 2001
    ..Fewer UVB exposures may also have other beneficial effects, i.e., shortened waiting lists and less risk to patients of developing cancer or photoaging of the skin...
  45. ncbi Histopathological changes seen in mycosis fungoides patients after phototherapy
    Duygu Dusmez Apa
    Department of Pathology, Mersin University, School of Medicine, Mersin 33079, Turkey
    Am J Dermatopathol 32:276-80. 2010
    ....
  46. ncbi Opposing effects of UVA1 phototherapy on the expression of bcl-2 and p53 in atopic dermatitis
    F Breuckmann
    Department of Dermatology, Ruhr-University, Bochum, Germany
    Arch Dermatol Res 293:178-83. 2001
    ..In summary, medium-dose UVA1 irradiation led to a marked modulation of the expression of p53 and bcl-2, and this plays a key role in regulating UVA1-induced apoptosis...
  47. ncbi [UVA1 phototherapy. Pilot study of dose finding in acute exacerbated atopic dermatitis]
    H C Dittmar
    Universitäts Hautklinik Freiburg, Hauptstrasse 7, 79104 Freiburg
    Hautarzt 52:423-7. 2001
    ..UVA1 phototherapy is an new effective treatment modality for acute atopic dermatitis (AD). However there is still some controversy about the optimal UVA1 single and cumulative dose...
  48. ncbi Combined treatment with calcipotriol ointment and low-dose ultraviolet A1 phototherapy in childhood morphea
    A Kreuter
    Department of Dermatology, Ruhr University Bochum, Bochum, Germany
    Pediatr Dermatol 18:241-5. 2001
    ..Further controlled studies are necessary to investigate whether this combined therapy is superior to UVA1 phototherapy alone...
  49. ncbi Efficacy of the 308-nm excimer laser for treatment of psoriasis: results of a multicenter study
    Steven R Feldman
    Department of Dermatology, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1071, USA
    J Am Acad Dermatol 46:900-6. 2002
    ..Our purpose was to demonstrate the efficacy of the 308-nm excimer laser for treatment of psoriasis...
  50. ncbi Ultraviolet A1 (340-400 nm) phototherapy for scleroderma in systemic sclerosis
    A Morita
    Department of Dermatology, Nagoya City University Medical School, Nagoya, Japan
    J Am Acad Dermatol 43:670-4. 2000
    ....
  51. ncbi Mononuclear cells in atopic dermatitis in vivo: immunomodulation of the cutaneous infiltrate by medium-dose UVA1 phototherapy
    F Breuckmann
    Department of Dermatology, Ruhr University Bochum, Germany
    Eur J Med Res 7:315-22. 2002
    ..The purpose of our study was to investigate the extent to which UVA1 irradiation is able to modulate the mononuclear dermal inflammatory infiltrate using different monoclonal antibodies...
  52. ncbi Cost-effectiveness analysis of a psoriasis care instruction programme with dithranol compared with UVB phototherapy and inpatient dithranol treatment
    M Hartman
    Department of Medical Technology Assessment 253 MTA, University Medical Centre St Radbound, PO Box 9101, 6500 HB Nijmegen, The Netherlands
    Br J Dermatol 147:538-44. 2002
    ..This study was part of a large national cost-effectiveness analysis, and was funded by the National Fund for Investigational Medicine of the Health Care Insurance Board...
  53. ncbi Narrowband UVB phototherapy for the treatment of psoriasis: a review and update
    J Barbagallo
    Department of Dermatology, St. Luke's-Roosevelt Hospital Center, New York, New York 10025, USA
    Cutis 68:345-7. 2001
    ..It is clearly more effective than broadband UVB, safer than PUVA, and well tolerated by patients when taken at suberythemogenic doses. Narrowband UVB represents an important new therapy for psoriasis...
  54. ncbi A randomized comparison of selective broadband UVB and narrowband UVB in the treatment of psoriasis
    Sandra M Kirke
    Department of Dermatology, Royal Victoria Infirmary, Newcastle upon Tyne, UK
    J Invest Dermatol 127:1641-6. 2007
    ..As these two lamp types appear to be of similar efficacy, phototherapy using a selective broadband source may be a safer option than use of narrowband UVB...
  55. ncbi Low-dose UVA1 phototherapy in systemic sclerosis: effects on acrosclerosis
    Alexander Kreuter
    Department of Dermatology and Allergology, Ruhr University Bochum, Bochum, Germany
    J Am Acad Dermatol 50:740-7. 2004
    ..Increased collagen synthesis, vascular damage, and T-lymphocytic infiltration contribute to the development of systemic sclerosis. Preliminary studies revealed the effectiveness of low-dose UVA1 phototherapy in acrosclerosis...
  56. ncbi [Ultraviolet-A1 (UVA1) phototherapy in lichen sclerosus et atrophicus]
    A Kreuter

    Hautarzt 52:878-81. 2001
    ..UVA1 phototherapy seems to be a new and effective treatment for LSA with optimal patients' acceptance due to the absence of systemic side effects. UVA1 should be therefore considered as therapeutic option for LSA...
  57. ncbi Reversal of brain dysfunction with UV-A1 irradiation in a patient with systemic lupus
    Y Menon
    Louisiana State University Medical School New Orleans, Louisiana 70112, USA
    Lupus 12:479-82. 2003
    ..Also of interest is that the UV-A1 irradiation, for the first time, ameliorated discoid lupus rashes, presumably due to a systemic action, as the lesions were for the first time covered during therapy...
  58. ncbi Low-dose ultraviolet-A1 phototherapy for lichen sclerosus et atrophicus
    A Kreuter
    Department of Dermatology, Ruhr-University Bochum, Germany
    Clin Exp Dermatol 26:30-2. 2001
    ..Long-wave UVA irradiation has been shown to induce intensively collagenase activity in human dermal fibroblasts. We suggest that UVA1 irradiation could be an effective treatment in patients suffering from extragenital LSA...
  59. ncbi UVA1 therapy for sclerodermic graft-versus-host disease of the skin
    Hartmut Ständer
    J Am Acad Dermatol 46:799-800. 2002
  60. ncbi Phototherapy for scleroderma: biologic rationale, results, and promise
    Gary J Fisher
    Department of Dermatology, University of Michigan, Ann Arbor, 48109 0609, USA
    Curr Opin Rheumatol 14:723-6. 2002
    ..Accumulating evidence indicates that UVA irradiation offers a genuine opportunity to ameliorate localized scleroderma and the cutaneous manifestations of systemic sclerosis...
  61. ncbi Effects of low dose ultraviolet A-1 phototherapy on morphea
    C J Gruss
    Department of Dermatology, University of Regensburg, Germany
    Photodermatol Photoimmunol Photomed 17:149-55. 2001
    ..Based on these data, the different types of phototherapy described in the literature and currently used for treatment of morphea are compared...
  62. ncbi Medium-dose UVA1 phototherapy in localized scleroderma and its effect in CD34-positive dendritic cells
    N R Camacho
    Department of Dermatology, School of Medicine, University of Puerto Rico, San Juan, Puerto Rico 00936-5067
    J Am Acad Dermatol 45:697-9. 2001
    ..CONCLUSION: Medium-dose UVA1 therapy is effective in the treatment of localized morphea. Effectiveness is associated with an increase in the number of CD34+ dendritic cells in the dermis...
  63. pmc Altered decorin expression of systemic sclerosis by UVA1 (340-400 nm) phototherapy: immunohistochemical analysis of 3 cases
    Hiroo Sawada
    Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya 467 8601, Japan
    BMC Dermatol 3:2. 2003
    ..In this study, we focus on the lesional expression of small dermatan sulfate proteoglycan, decorin that has a role of binding to collagen and fibrillogenesis...
  64. ncbi Whole-body UVB (TL-01) or UVA-1 irradiation does not alter the levels of immunomodulatory cytokines in the serum of human volunteers
    P McLoone
    Photobiology Unit, Ninewells Hospital and Medical School, Dundee, UK
    Photodermatol Photoimmunol Photomed 20:76-80. 2004
    ..To investigate whether there was a parallel mechanism in humans we examined the effect of whole-body narrowband ultraviolet B (UVB) (311-313 nm; TL-01) and ultraviolet A (UVA)-1 (340-400 nm) on serum cytokine levels...
  65. pmc UVA-1 cold light treatment of SLE: a double blind, placebo controlled crossover trial
    M C Polderman
    Department of Dermatology, Leiden University Medical Centre, The Netherlands
    Ann Rheum Dis 60:112-5. 2001
    ..In the current study low dose UVA-1 cold light treatment was tested to determine whether it reduces disease activity in SLE...
  66. ncbi Pansclerotic morphea treated with UVA: a case report
    Mehmet Yildirim
    Department of Dermatology, University of Suleyman Demirel, School of Medicine, Isparta, Turkey
    J Dermatol 30:625-7. 2003
    ..Various systemic agents and PUVA are used in the treatment of this disease. We used UVA therapy in the treatment of this case...
  67. ncbi UVA1 irradiation induces deoxyribonuclease dependent apoptosis in cutaneous T-cell lymphoma in vivo
    G von Kobyletzki
    Department of Dermatology, Ruhr University, Bochum, Germany
    Photodermatol Photoimmunol Photomed 16:271-7. 2000
    ....
  68. ncbi Evaluation of medium-dose UVA1 phototherapy in localized scleroderma with the cutometer and fast Fourier transform method
    M A De Rie
    Department of Dermatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
    Dermatology 207:298-301. 2003
    ..To evaluate the efficacy of medium-dose UVA1 phototherapy in patients with localized scleroderma...
  69. ncbi Comparison of the efficacy of calcipotriol and maxacalcitol in combination with narrow-band ultraviolet B therapy for the treatment of psoriasis vulgaris
    Reiko Noborio
    Department of Geriatric and Environmental Dermatology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    Photodermatol Photoimmunol Photomed 22:262-4. 2006
    ..We compared the efficacy of the topical vitamin D(3) derivatives calcipotriol and maxacalcitol in combination therapy...
  70. ncbi Angiogenic activity in patients with psoriasis is significantly decreased by Goeckerman's therapy
    C Andrys
    Department of Clinical Immunology and Allergy, School of Medicine, Charles University in Prague, Hradec Kralove, Czech Republic
    Arch Dermatol Res 298:479-83. 2007
    ..0319). In conclusion, we found that the angiogenic potential which is abnormally increased in patients with psoriasis is significantly alleviated by GT...
  71. ncbi Patients with moderate-to-severe plaque psoriasis preferred oral therapies to phototherapies: a preference assessment based on clinical scenarios with trade-off questions
    B C Opmeer
    Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, University of Amsterdam, P O Box 22660, 1100 DD, Amsterdam, The Netherlands
    J Clin Epidemiol 60:696-703. 2007
    ..As an alternative, we assessed patients' treatment preferences and trade-offs for five common systemic therapies for psoriasis...
  72. ncbi Psoriasis: disease management with a brief review of new biologics
    Amor Khachemoune
    SUNY Downstate Medical Center, Brooklyn, NY, USA
    Dermatol Nurs 18:40-3, 49. 2006
    ..Given the chronic nature of the disease, goal of treatment is to induce and maintain remission, with minimal short and long-term side effects from therapy. Most agents can be used alone or in combination with other treatment modalities...
  73. ncbi Treatment of psoriasis vulgaris with narrow-band UVB and topical Maxacalcitol
    Tomonori Takekoshi
    Acta Derm Venereol 86:375-6. 2006
  74. ncbi Calcipotriol (Dovobet) ointment in combination with UVB therapy for psoriasis treatment
    Corrie Rogers
    Phototherapy Education and Research Centre, Women s College Hospital, Toronto, Ontario, Canada
    Dermatol Nurs 18:258-61. 2006
    ..Light therapy was increased by 10% increments at each visit or as tolerated by the patient. Results show the combination of light therapy plus Dovobet may be an effective and convenient option in the treatment of psoriasis...
  75. ncbi [Maintenance therapy of psoriasis]
    J Wohlrab
    Universitätsklinik und Poliklinik für Dermatologie und Venerologie, Institut für angewandte Dermatopharmazie, Martin Luther Universitat Halle Wittenberg, Ernst Kromayer Strasse 5, 06097, Halle, Germany
    Hautarzt 57:661-5. 2006
    ..These effects may be supplemented by pharmacological or biochemical effects of the active substances or substance mixtures. Focal points are the use of lipophilic bases as well as keratoplastic, antiseptic and antipruriginous additives...
  76. ncbi Treatment of palmoplantar psoriasis with monochromatic excimer light (308-nm) versus cream PUVA
    Norbert J Neumann
    Department of Dermatology, Heinrich Heine University Duesseldorf, Germany
    Acta Derm Venereol 86:22-4. 2006
    ..This might lead to a lower incidence of adverse reactions and better compliance. Therefore, monochromatic excimer light therapy seems to be a useful new therapeutic option for palmoplantar psoriasis...
  77. ncbi Tacrolimus ointment 0.1% alone and in combination with medium-dose UVA1 in the treatment of palmar or plantar psoriasis
    Jennifer Rivard
    Department of Dermatology, Henry Ford Hospital, Detroit, MI 48202, USA
    J Drugs Dermatol 5:505-10. 2006
    ..No dramatic changes in plaque thickness or scaling were seen with either tacrolimus alone or with the combination of tacrolimus and medium dose UVA1 on palmar or plantar psoriasis...
  78. ncbi Effect of PUVA, narrow-band UVB and cyclosporin on inflammatory cells of the psoriatic plaque
    Gul Erkin
    Department of Dermatology, Hacettepe University School of Medicine, Sihhiye, Ankara, Turkey
    J Cutan Pathol 34:213-9. 2007
    ..In this study, our purpose was to evaluate and compare effects of PUVA, cyclosporine A and narrow-band UVB on dendritic cells and activated lymphocytes in the psoriatic lesions...
  79. ncbi Soluble tumour necrosis factor-alpha receptor type 1 as a biomarker of response to phototherapy in patients with psoriasis
    Agnieszka B Serwin
    Department of Dermatology and Venereology, Medical University of Bialystok 14, Zurawia St 15 540 Bialystok, Poland
    Biomarkers 12:599-607. 2007
    ..The results suggest that the value of serum sTNF-R1 concentration as a marker of response to phototherapy may depend on duration of skin lesions and the treatment method...
  80. ncbi A pragmatic randomized controlled trial on the effectiveness of highly concentrated saline spa water baths followed by UVB compared to UVB only in moderate to severe psoriasis
    Thomas Brockow
    Spa Medicine Research Institute, Bad Elster, Germany
    J Altern Complement Med 13:725-32. 2007
    ..There is a lack of sufficiently large randomized trials evaluating the effectiveness of saline spa balneophototherapy compared to ultraviolet B (UVB) only...
  81. ncbi A pragmatic randomized controlled trial on the effectiveness of low concentrated saline spa water baths followed by ultraviolet B (UVB) compared to UVB only in moderate to severe psoriasis
    T Brockow
    Spa Medicine Research Institute, Bad Elster, Germany
    J Eur Acad Dermatol Venereol 21:1027-37. 2007
    ..To evaluate whether low concentrated saline spa water baths followed by ultraviolet B (LC-SSW-UVB) are superior to UVB alone in moderate to severe psoriasis...
  82. ncbi Narrowband UV-B phototherapy, alefacept, and clearance of psoriasis
    Franz J Legat
    Research Unit for Photodermatology, Department of Dermatology, Medical University of Graz, Auenbruggerplatz 8, A 8036 Graz, Austria
    Arch Dermatol 143:1016-22. 2007
    ..To determine whether the addition of 311-nm narrowband UV-B (NB UV-B) phototherapy accelerates and improves the therapeutic efficacy of alefacept, a biological antipsoriatic drug approved for the treatment of moderate to severe psoriasis...
  83. ncbi Clinical effect of vitamin D3 analogues is not inactivated by subsequent UV exposure
    Yuka Adachi
    Department of Dermatology, Kanssai Medical University, Osaka, Japan
    Photodermatol Photoimmunol Photomed 24:16-8. 2008
    ..Experimental investigations demonstrated that calcipotriol is degraded by UV radiation, and suggested that calcipotriol should be applied after phototherapy but not immediately before...
  84. ncbi Comparison of the efficacy of local narrowband ultraviolet B (NB-UVB) phototherapy versus psoralen plus ultraviolet A (PUVA) paint for palmoplantar psoriasis
    Engin Sezer
    Department of Dermatology, Gaziosmanpasa University School of Medicine, Tokat, Turkey
    J Dermatol 34:435-40. 2007
    ....
  85. ncbi Utilization of narrow-band ultraviolet light B therapy and etanercept for the treatment of psoriasis (UNITE): efficacy, safety, and patient-reported outcomes
    Leon Kircik
    Department of Dermatology, Indiana University School of Medicine, Indianapolis, IN, USA
    J Drugs Dermatol 7:245-53. 2008
    ..Etanercept and narrow-band ultraviolet light B (NB-UVB) are widely used to treat this disease...
  86. ncbi Lack of effect of oral selenite on p53 associated gene expression during TL01 therapy of psoriasis patients
    Bernadette DeSilva
    Dermatology, University of Edinburgh, Edinburgh, UK
    Photodermatol Photoimmunol Photomed 23:98-100. 2007
    ..Following the TL01 therapy, no significant difference was observed for any of these markers when the Se group was compared with the placebo group of patients, although p53 and Bcl-2 expression decreased in the Se supplemented group...
  87. ncbi Bath PUVA and saltwater baths followed by UV-B phototherapy as treatments for psoriasis: a randomized controlled trial
    Ralf Schiener
    Department of Dermatology, University of Ulm, Germany
    Arch Dermatol 143:586-96. 2007
    ....
  88. ncbi Discrepant levels of vascular endothelial growth factor in psoriasis patients treated with PUVA, Re-PUVA and narrow-band UVB
    Ayse Akman
    Department of Dermatology, Akdeniz University School of Medicine, Antalya, Turkey
    Photodermatol Photoimmunol Photomed 24:123-7. 2008
    ..However, to our knowledge, no studies have evaluated the effects of PUVA, Re-PUVA and narrow-band UVB (NB-UVB) treatments on serum levels of VEGF in patients with psoriasis...
  89. ncbi [Psoralen improves effectiveness. With water and light to control of psoriasis]
    Helga Brettschneider
    MMW Fortschr Med 149:20. 2007
  90. ncbi A randomized, double-blind, vehicle-controlled, bilateral comparison trial of bexarotene gel 1% versus vehicle gel in combination with narrowband UVB phototherapy for moderate to severe psoriasis vulgaris
    Melissa Amy Magliocco
    Psoriasis Center of Excellence, University of Medicine and Dentistry of New Jersey Robert Wood Johnson Medical School, New Brunswick, New Jersey 08901 0019, USA
    J Am Acad Dermatol 54:115-8. 2006
    ..NBUVB was initiated 2 weeks after topical therapy began. Limitations include small sample size and interim analysis. Based on analysis of target lesion scores, bexarotene gel 1%/NBUVB was significantly more effective than placebo/NBUVB...
  91. ncbi Treatments for mild-to-moderate recalcitrant plaque psoriasis: expected clinical and economic outcomes for first-line and second-line care
    Albert Marchetti
    Medical Education and Research Alliance Med ERA, 145 West 58th Street, New York, NY 10019, USA
    Dermatol Online J 11:1. 2005
    ....
  92. ncbi [Phototherapy and photochemotherapy of inflammatory dermatoses]
    R Schiener
    Abteilung Dermatologie, Venerologie und Allergologie, Bundeswehrkrankenhaus Ulm
    MMW Fortschr Med 145:45-7. 2003
    ..The patient must also be informed of such undesired potential side effects as burns and premature aging of the skin...
  93. ncbi Effects of topical petrolatum and salicylic acid upon skin photoreaction to UVA
    Bahar Birgin
    Department of Dermatology, University of Dokuz Eylul, Faculty of Medicine, 35340 Izmir, Turkey
    Eur J Dermatol 15:156-8. 2005
    ..The application of petrolatum and salicylic acid in petrolatum just before PUVA therapy is not recommended because of their blocking effects...
  94. ncbi Phototherapy arsenal in the treatment of psoriasis
    Michael Zanolli
    Dermatology Consultants, PC, 4230 Harding Road, Suite 609 East, Nashville, TN 37205, USA
    Dermatol Clin 22:397-406, viii. 2004
    ....
  95. ncbi Vitiligo. Pathogenesis and treatment
    M D Njoo
    Department of Dermatology, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
    Am J Clin Dermatol 2:167-81. 2001
    ..In widespread vitiligo, residual pigment can be removed by depigmentation agents. Sunscreens, camouflage products, and good guidance may help the patient cope better with the disease...
  96. ncbi Therapeutic options in the treatment of psoriasis and atopic dermatitis
    Alice B Gottlieb
    Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, New Brunswick, NJ 08901, USA
    J Am Acad Dermatol 53:S3-16. 2005
    ..In many of these categories, a number of exciting new therapies are in development that may augment the existing armamentarium available to clinicians for the treatment of inflammatory skin diseases...
  97. ncbi Combination therapy with vitamin D analogues
    S Lamba
    Department of Dermatology, Mount Sinai Medical Center, New York 10029-6574, USA
    Br J Dermatol 144:27-32. 2001
    ..As long as treatments are used correctly, the benefits of combination therapy with vitamin D analogues usually outweigh the few drawbacks...
  98. ncbi A clinician's paradigm in the treatment of psoriasis
    Mark Lebwohl
    Department of Dermatology, Mount Sinai School of Medicine, New York, New York 10029, USA
    J Am Acad Dermatol 53:S59-69. 2005
    ..Because some degree of therapy will always be necessary, ranging from maintenance of long-term remission to control of acute psoriasis flares, each patient requires an individualized plan...
  99. ncbi Comparative efficacy of psoralen - UVA photochemotherapy versus narrow band UVB phototherapy in the treatment of psoriasis
    Raheel Tahir
    Department of Dermatology, Nishtar Medical College and Hospital, Multan
    J Coll Physicians Surg Pak 14:593-5. 2004
    ..To compare the clinical improvement in psoriasis with psoralen - UVA photochemotherapy versus narrow band UVB phototherapy alone...
  100. ncbi UV-B phototherapy clears psoriasis through local effects
    Robert S Dawe
    Photobiology Unit, Department of Dermatology, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland
    Arch Dermatol 138:1071-6. 2002
    ..To determine if UV-B phototherapy clears psoriasis through systemic effects...
  101. ncbi Narrowband UV-B (TL-01) phototherapy vs oral 8-methoxypsoralen psoralen-UV-A for the treatment of chronic plaque psoriasis
    T Markham
    City of Dublin Skin and Cancer Hospital, Hume St, Dublin 2, Ireland
    Arch Dermatol 139:325-8. 2003
    ..To compare the efficacy of narrowband UV-B (TL-01) phototherapy with oral 8-methoxypsoralen photochemotherapy (8-MOP psoralen-UV-A [PUVA]) in patients with chronic plaque psoriasis (CPP)...

Research Grants8

  1. Investigating the Risk of Lymphoma in Psoriasis Patients
    Joel Gelfand; Fiscal Year: 2008
    ....
  2. IMMUNOLOGICAL CONSEQUENCES OF TRANSFUSION
    Loren Fast; Fiscal Year: 2002
    ..abstract_text> ..
  3. Surrogate markers of complete venous ulcer healing
    Joel Gelfand; Fiscal Year: 2002
    ..Through conducting these studies and pursuing the MSCE, the investigator will develop a series of epidemiological tools for which to apply to future scientific investigations. ..
  4. NEONATAL BILIRUBIN NEUROTOXICITY AND P-GLYCOPROTEIN
    Jon Watchko; Fiscal Year: 2007
    ..abstract_text> ..
  5. Vitamin D insufficiency: Prevalence and Impact in Young School Age Children
    Kumaravel Rajakumar; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  6. SURFACE ANTIGENS OF TREPONEMA PALLIDUM
    Wesley Van Voorhis; Fiscal Year: 2008
    ..Finally, these studies will help define the protective immune response that results after immunization with Tp92 as well as the immune response to Tp92 that occurs during infection. [unreadable] [unreadable]..
  7. Homeostasis of dendritic cells and GVHD
    Miriam Merad; Fiscal Year: 2010
    ..These studies should provide valuable insights into LC regulation of skin immune responses and may lead to improved prevention or treatment of skin GVHD, a major medical problem in transplantation therapy of patients with malignancies. ..
  8. Dissecting the origin and the function of the cutaneous dendritic cell network
    Miriam Merad; Fiscal Year: 2010
    ..Program Director/Principal Investigator (Last, First, Middle): Merad, Miriam 1R01 AI080884-01A1 DISSECTING THE ORIGIN AND THE FUNCTION OF THE CUTANEOUS DENDRTITIC CELL NETWORK ..