fetoscopy

Summary

Summary: Endoscopic examination, therapy or surgery of the fetus and amniotic cavity through abdominal or uterine entry.

Top Publications

  1. ncbi Monochorionic diamniotic twins: complications and management options
    Liesbeth Lewi
    Department of Obstetrics and Gynecology, University Hospital Gasthuisberg, Centre for Surgical Technologies, Faculty of Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    Curr Opin Obstet Gynecol 15:177-94. 2003
  2. ncbi Cervical length as a prognostic factor for preterm delivery in twin-to-twin transfusion syndrome treated by fetoscopic laser coagulation of chorionic plate anastomoses
    R Robyr
    Department of Obstetrics and Gynecology, Paris Ouest University Versailles St Quentin, Paris, France
    Ultrasound Obstet Gynecol 25:37-41. 2005
  3. ncbi Twin-to-twin transfusion syndrome: management options and outcomes
    Masami Yamamoto
    Unidad de ecografia, Clinica Alemana, Hospital Padre Hurtado, Universidad del Desarrollo, Santiago, Chile
    Clin Obstet Gynecol 48:973-80. 2005
  4. ncbi Transient chorioamniotic membrane separation after fetoscope guide laser therapy for twin-twin transfusion syndrome: a case report
    Yao Lung Chang
    Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Medical Center, Chang Gung University College of Medicine Taoyuan, Taoyuan, Taiwan, ROC
    Fetal Diagn Ther 22:180-2. 2007
  5. ncbi Fetal surgery for anesthesiologists
    Jan A Deprest
    Division Woman and Child, Fetal Medicine Unit, University Hospitals Leuven, Belgium
    Curr Opin Anaesthesiol 21:298-307. 2008
  6. ncbi Improved recipient survival with maternal nifedipine in twin-twin transfusion syndrome complicated by TTTS cardiomyopathy undergoing selective fetoscopic laser photocoagulation
    Timothy M Crombleholme
    The Fetal Care Center of Cincinnati, Division of Pediatric General, Thoracic, and Fetal Surgery, Cincinnati Children s Hospital, Cincinnati, OH 45229 3039, USA
    Am J Obstet Gynecol 203:397.e1-9. 2010
  7. ncbi Maternal pulmonary edema during fetoscopic surgery
    Marnie B Robinson
    Department of Anesthesiology, Cincinnati Children s Hospital and Medical Center, Cincinnati, Ohio, USA
    Anesth Analg 107:1978-80. 2008
  8. ncbi Operative fetoscopy: new perspective in fetal therapy?
    J A Deprest
    Department of Obstetrics and Gynaecology, University Hospitals Leuven, Belgium
    Prenat Diagn 17:1247-60. 1997
  9. ncbi Biochemical composition of fluids for amnioinfusion during fetoscopy
    P N Adama van Scheltema
    Fetal Diagnosis and Therapy Unit, Department of Obstetrics, Leiden University Medical Centre, Leiden, The Netherlands
    Gynecol Obstet Invest 66:227-30. 2008
  10. ncbi Neonatal outcome in preterm monochorionic twins with twin-to-twin transfusion syndrome after intrauterine treatment with amnioreduction or fetoscopic laser surgery: comparison with dichorionic twins
    Richard Lenclen
    Department of Neonatology, Paris Ouest University, CHI Poissy St Germain, France
    Am J Obstet Gynecol 196:450.e1-7. 2007

Research Grants

  1. Miniature Laser Therapy Endoscope
    Guillermo Tearney; Fiscal Year: 2009
  2. DERMAL-EPIDERMAL INTERACTIONS IN DIABETIC WOUND HEALING
    Timothy Crombleholme; Fiscal Year: 2004
  3. Twin-Twin Transfusion Syndrome Trial
    Timothy Crombleholme; Fiscal Year: 2004
  4. Endothelial Progenitor Cell Recruitment in Diabetic Mice
    Timothy Crombleholme; Fiscal Year: 2008
  5. Endothelial Progenitor Cell Biology in Type 1 Diabetes
    Timothy Crombleholme; Fiscal Year: 2008
  6. Mechanisms of Scar-Free Healing in the Fetal Artery
    DARRELL CASS; Fiscal Year: 2008
  7. UROTHELIAL DIFFENTIATION
    Laurence Baskin; Fiscal Year: 2003

Detail Information

Publications192 found, 100 shown here

  1. ncbi Monochorionic diamniotic twins: complications and management options
    Liesbeth Lewi
    Department of Obstetrics and Gynecology, University Hospital Gasthuisberg, Centre for Surgical Technologies, Faculty of Medicine, Katholieke Universiteit Leuven, Leuven, Belgium
    Curr Opin Obstet Gynecol 15:177-94. 2003
    ..This is because of the unpredictable vascular anastomoses and the often asymmetrical distribution of the single placenta between both twins...
  2. ncbi Cervical length as a prognostic factor for preterm delivery in twin-to-twin transfusion syndrome treated by fetoscopic laser coagulation of chorionic plate anastomoses
    R Robyr
    Department of Obstetrics and Gynecology, Paris Ouest University Versailles St Quentin, Paris, France
    Ultrasound Obstet Gynecol 25:37-41. 2005
    ....
  3. ncbi Twin-to-twin transfusion syndrome: management options and outcomes
    Masami Yamamoto
    Unidad de ecografia, Clinica Alemana, Hospital Padre Hurtado, Universidad del Desarrollo, Santiago, Chile
    Clin Obstet Gynecol 48:973-80. 2005
  4. ncbi Transient chorioamniotic membrane separation after fetoscope guide laser therapy for twin-twin transfusion syndrome: a case report
    Yao Lung Chang
    Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Linkou Medical Center, Chang Gung University College of Medicine Taoyuan, Taoyuan, Taiwan, ROC
    Fetal Diagn Ther 22:180-2. 2007
    ..There was no more CMS noted till delivery at gestational age of 34 weeks 6 days. CMS after fetoscope surgery may reseal spontaneously...
  5. ncbi Fetal surgery for anesthesiologists
    Jan A Deprest
    Division Woman and Child, Fetal Medicine Unit, University Hospitals Leuven, Belgium
    Curr Opin Anaesthesiol 21:298-307. 2008
    ..We aimed to review the current clinical status and advances in endoscopic and open surgical interventions on the fetus in terms of indications, technical aspects and reported outcomes...
  6. ncbi Improved recipient survival with maternal nifedipine in twin-twin transfusion syndrome complicated by TTTS cardiomyopathy undergoing selective fetoscopic laser photocoagulation
    Timothy M Crombleholme
    The Fetal Care Center of Cincinnati, Division of Pediatric General, Thoracic, and Fetal Surgery, Cincinnati Children s Hospital, Cincinnati, OH 45229 3039, USA
    Am J Obstet Gynecol 203:397.e1-9. 2010
    ..The purpose of this study was to evaluate the effect of maternal nifedipine on fetal survival when started 24-48 hours before selective fetoscopic laser photocoagulation (SFLP)...
  7. ncbi Maternal pulmonary edema during fetoscopic surgery
    Marnie B Robinson
    Department of Anesthesiology, Cincinnati Children s Hospital and Medical Center, Cincinnati, Ohio, USA
    Anesth Analg 107:1978-80. 2008
    ..We hypothesize that the pulmonary edema resulted from irrigating fluid (totaling net 8 L) absorbed i.v. through myometrial venous channels accessed by passage of the operating trocars...
  8. ncbi Operative fetoscopy: new perspective in fetal therapy?
    J A Deprest
    Department of Obstetrics and Gynaecology, University Hospitals Leuven, Belgium
    Prenat Diagn 17:1247-60. 1997
    ..More recently the merger of fetoscopy and advanced video-endoscopic surgery has been the basis of the concept of endoscopic fetal surgery...
  9. ncbi Biochemical composition of fluids for amnioinfusion during fetoscopy
    P N Adama van Scheltema
    Fetal Diagnosis and Therapy Unit, Department of Obstetrics, Leiden University Medical Centre, Leiden, The Netherlands
    Gynecol Obstet Invest 66:227-30. 2008
    To evaluate which of the commercially available solutions is best suited for amnioinfusion during fetoscopy, based on resemblance with the biochemical properties of amniotic fluid.
  10. ncbi Neonatal outcome in preterm monochorionic twins with twin-to-twin transfusion syndrome after intrauterine treatment with amnioreduction or fetoscopic laser surgery: comparison with dichorionic twins
    Richard Lenclen
    Department of Neonatology, Paris Ouest University, CHI Poissy St Germain, France
    Am J Obstet Gynecol 196:450.e1-7. 2007
    ....
  11. ncbi Endoscopic laser surgery in severe second-trimester twin-twin transfusion syndrome: a three-year experience from a Latin American center
    Waldo Sepulveda
    Fetal Medicine Center, Department of Obstetrics and Gynecology, Clinica Las Condes, Santiago, Chile
    Prenat Diagn 27:1033-8. 2007
    ....
  12. ncbi Laser coagulation of placental anastomoses with a 30 degrees fetoscope in severe mid-trimester twin-twin transfusion syndrome with anterior placenta
    A Huber
    Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg Eppendorf UKE, Hamburg, Germany
    Ultrasound Obstet Gynecol 31:412-6. 2008
    ....
  13. ncbi Laser treatment in twin-to-twin transfusion syndrome
    Masami Yamamoto
    Service de Gynecologie Obstetrique, CHI Poissy Saint Germain en Laye, Université de Paris Ouest, Versailles St Quentin en Yvelines, 10 Rue de Champ Gaillard, Poissy 78300, France
    Semin Fetal Neonatal Med 12:450-7. 2007
    ..The overall survival rate at birth was 66% (1894/2869). However, variations in survival rates between centres and inconsistency in the reporting of complications call for more homogeneity in the pre- and post-operative assessment...
  14. ncbi Interventions for twin-twin transfusion syndrome: a Cochrane review
    D Roberts
    Department of Obstetrics and Gynaecology, Liverpool Women s NHS Foundation Trust, Liverpool, UK
    Ultrasound Obstet Gynecol 31:701-11. 2008
    ..58; 95% CI, 0.18-1.86 adjusted for clustering; one trial). The results suggest that endoscopic laser coagulation of anastomotic vessels should be considered in the treatment of all stages of TTTS to improve perinatal and neonatal outcome...
  15. ncbi Transabdominal fetoscopy in fetal anomalies diagnosed by ultrasound in the first trimester of pregnancy
    Y Ville
    Unité de Médecine Foetale et de Diagnostic Antenatal, Service de Gynécologie Obstétrique hôpital A Béclère, Clamart, France
    Ultrasound Obstet Gynecol 8:11-5. 1996
    ..We describe a microendoscope that can be used with an 18-gauge needle at the time of amniocentesis to provide more precise diagnostic information when the first-trimester ultrasound examination suggests a problem...
  16. ncbi First-trimester needle embryofetoscopy and prenatal diagnosis
    E A Reece
    Department of Obstetrics, Gynecology and Reproductive Sciences, Temple University School of Medicine, Philadelphia, PA 19140, USA
    Fetal Diagn Ther 12:136-9. 1997
    ..To demonstrate the efficacy of first-trimester needle embryofetoscopy (or embryoscopy) for prenatal diagnosis in a continuing pregnancy...
  17. ncbi Fetoscopy-guided fetal endoscopy in a sheep model
    F I Luks
    Centre of Surgical Technologies, University Hospital Gasthuisberg, Catholic University of Leuven, Belgium
    J Am Coll Surg 178:609-12. 1994
    ..This technique, however, could become a valuable research tool to study fetal gastrointestinal and pulmonary physiologic factors in situ...
  18. ncbi Transabdominal thin-gauge embryofetoscopy: a technique for early prenatal diagnosis and its use in the diagnosis of a case of Meckel-Gruber syndrome
    R A Quintero
    Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut
    Am J Obstet Gynecol 168:1552-7. 1993
    ..Our aim was to develop and evaluate a transabdominal endoscopic technique to visualize the embryo or fetus with thin-gauge needles and submillimetric fiberoptic endoscopes...
  19. ncbi Intrafetal alcohol chemosclerosis of acardiac twins: a multicenter experience
    Waldo Sepulveda
    Fetal Medicine Center, Clinica Las Condes, Santiago, Chile
    Fetal Diagn Ther 19:448-52. 2004
    ..To report a multicenter experience with intrafetal alcohol chemosclerosis in the treatment of pregnancies complicated with the twin reversed arterial perfusion sequence...
  20. ncbi Twin-twin transfusion syndrome: a review of treatment option
    Stefania Fieni
    Department of Gynecology, Obstetrics and Neonatology, University of Parma, Parma, Italy
    Acta Biomed 75:34-9. 2004
    ..More recently, laser ablation under fetoscopic guidance of placental vessel has been reported in an attempt to improve survival. The objective of this review was to evaluate the impact of treatment modalities in TTTS...
  21. ncbi Re: Stage-based treatment of twin-twin transfusion syndrome
    Nicholas M Fisk
    Am J Obstet Gynecol 190:1809-10; author reply 1810-11. 2004
  22. ncbi Recent advances in fetal surgery
    Raul A Cortes
    Division of Pediatric Surgery, The Fetal Treatment Center, University of California, San Frncisrco, CA 94143 0570, USA
    Semin Perinatol 28:199-211. 2004
    ..Fetal surgery as a (multi)discipline continues to strive to minimize maternal and fetal risk. Undoubtedly, as tocolytic therapy and neonatal intensive efforts improve, fetal therapy will expand...
  23. ncbi [The initial results of fetoscopic laser treatment for severe second trimester twin-to-twin transfusion syndrome in the Netherlands are comparable to international results]
    J M Middeldorp
    afd Verloskunde, Leids Universitair Medisch Centrum, Postbus 9600, 2300 RC Leiden
    Ned Tijdschr Geneeskd 148:1203-8. 2004
    ..Evaluation of the initial results of selective fetoscopic laser coagulation of placental blood vessels for severe second-trimester twin-to-twin transfusion syndrome in the Netherlands...
  24. ncbi Incidence, mechanisms, and patterns of fetal cerebral lesions in twin-to-twin transfusion syndrome
    Edwin Quarello
    Department of Obstetrics and Gynecology, CHI Poissy St Germain en Laye, Universite Paris Ouest, Poissy, France
    J Matern Fetal Neonatal Med 20:589-97. 2007
    ..To determine the incidence of fetal cerebral lesions and their characteristics in twin-to-twin transfusion syndrome (TTTS)...
  25. ncbi Fetoscopic laser treatment of twin-to-twin transfusion syndrome followed by severe twin anemia-polycythemia sequence with spontaneous resolution
    E Lopriore
    Division of Neonatology, Department of Pediatrics, Leiden University Medical Centre, Leiden, The Netherlands
    Am J Obstet Gynecol 198:e4-7. 2008
    ..No residual anastomoses were identified after placental injection with colored dye. We discuss the possible pathogenetic mechanisms that may have led to this remarkable clinical course and discuss the various management options...
  26. ncbi Fetal lung volume after endoscopic tracheal occlusion in the prediction of postnatal outcome
    Cleisson F A Peralta
    Department of Obstetrics and Gynecology, Fetal Medicine Units, King s College Hospital, London, United Kingdom
    Am J Obstet Gynecol 198:60.e1-5. 2008
    ..The objective of the study was to investigate the volume response of the contralateral lung in the prediction of postnatal outcome in fetuses with congenital diaphragmatic hernia (CDH) treated by fetoscopic endotracheal occlusion (FETO)...
  27. ncbi Minimal-access fetal surgery for twin-to-twin transfusion syndrome
    J G Bussey
    Program in Fetal Medicine, Hasbro Children s Hospital, Brown Medical School, 2 Dudley Street, Suite 180, Providence, RI 02905, USA
    Surg Endosc 18:83-6. 2004
    ..The authors present the technical aspects of endoscopic fetal surgery in their initial clinical experience...
  28. ncbi Encouraging early clinical experience with deliberately delayed temporary fetoscopic tracheal occlusion for the prenatal treatment of life-threatening right and left congenital diaphragmatic hernias
    Thomas Kohl
    German Center for Fetal Surgery and Minimally Invasive Therapy, University Hospital of Bonn, Germany
    Fetal Diagn Ther 21:314-8. 2006
    ..In order to assess the effect of deliberately delayed percutaneous fetoscopic tracheal occlusion on survival of fetuses with life-threatening congenital diaphragmatic hernia...
  29. ncbi Twin-to-twin transfusion syndrome
    C M A Andrade
    Fetal Medicine Unit, Obstetrics Department, Sao Paulo Federal University, 04126 010 São Paulo, SP, Brazil
    Int J Gynaecol Obstet 98:154-5. 2007
  30. ncbi Risk of persistent pulmonary hypertension of the neonate in twin-to-twin transfusion syndrome
    Bas Delsing
    Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands
    Neonatology 92:134-8. 2007
    ..Chronic twin-to-twin transfusion syndrome (TTTS) is a complication of monochorionic twin gestations and is associated with high perinatal mortality and increased neurological, cardiovascular and renal morbidity...
  31. ncbi Residual anastomoses after fetoscopic laser surgery in twin-to-twin transfusion syndrome: frequency, associated risks and outcome
    E Lopriore
    Division of Neonatology, Department of Pediatrics, Leiden University Medical Center, Leiden, The Netherlands
    Placenta 28:204-8. 2007
    ..Although residual anastomoses in our study were not associated with adverse outcome, they were often associated with neonatal hematological complications...
  32. ncbi Manifestation of mirror syndrome after fetoscopic laser photocoagulation in severe twin-twin transfusion syndrome
    Satoshi Hayashi
    Division of Fetal Medicine, Department of Perinatal Medicine and Maternal Care, National Center for Child Health and Development, Tokyo, Japan
    Fetal Diagn Ther 21:51-4. 2006
    ..We report here a case of mirror syndrome that occurred after selective fetoscopic laser photocoagulation in severe TTTS at 24 weeks' gestation...
  33. ncbi Combined sonographic and endoscopic umbilical cord occlusion in twin and triplet gestations
    Bruce K Young
    Division of Maternal Fetal Medicine, New York University School of Medicine, New York 10016, USA
    J Perinat Med 33:530-3. 2005
    ..To review our experience with a minimally invasive technique for umbilical cord occlusion as a method of selective feticide in monochorionic sets...
  34. ncbi Prenatal intervention for isolated congenital diaphragmatic hernia
    Jan Deprest
    Fetal Medicine Unit, Department of Obstetrics and Gynaecology, University Hospital Gasthuisberg, Leuven, Belgium
    Curr Opin Obstet Gynecol 18:355-67. 2006
    ..We aim to review the recent literature regarding early prenatal prediction of outcome in babies diagnosed with isolated congenital diaphragmatic hernia, as well as results of fetal therapy for this condition...
  35. ncbi Analysis of fetal growth after laser therapy in twin-to-twin transfusion syndrome
    Renato A Moreira de Sa
    Department of Obstetrics and Gynecology, centre hospitalier intercommunal de Poissy St Germain en Laye, Poissy, France
    J Ultrasound Med 24:1213-9; quiz 1220-1. 2005
    ..The purpose of this study was to evaluate fetal growth patterns after laser therapy in twin-to-twin transfusion syndrome (TTTS)...
  36. ncbi Magnetic resonance imaging of the feto-placentar unit after fetoscopic laser coagulation for twin-to-twin transfusion syndrome
    T A G M Huisman
    Department of Diagnostic Imaging, University Children s Hospital Zurich, Zurich, Switzerland
    Acta Radiol 46:328-30. 2005
    ..The purpose of this report is to present and discuss fetal magnetic resonance imaging as a postoperative imaging tool after fetoscopic laser coagulation...
  37. ncbi Twin reversed arterial perfusion: fetoscopic laser coagulation of placental anastomoses or the umbilical cord
    K Hecher
    Department of Obstetrics and Fetal Medicine, University Medical Centre Hamburg Eppendorf, Hamburg, Germany
    Ultrasound Obstet Gynecol 28:688-91. 2006
    ..To assess the feasibility and outcome of fetoscopic laser coagulation in pregnancies with twin reversed arterial perfusion (TRAP) sequence...
  38. ncbi Fetoscopic laser therapy for twin-twin transfusion syndrome
    Yao Lung Chang
    Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Tao Yuan, Taiwan
    Taiwan J Obstet Gynecol 45:294-301. 2006
    ....
  39. ncbi Selective cord coagulation in acardiac twins
    W Diehl
    Department of Obstetrics and Fetal Medicine, University Medical Centre, Hamburg Eppendorf UKE, Martinistrasse 52, 20246 Hamburg, Germany
    Semin Fetal Neonatal Med 12:458-63. 2007
    ....
  40. ncbi Twin-to-twin transfusion syndrome
    Virginia Kinnick
    University of Northern Colorado School of Nursing, Greeley, USA
    AWHONN Lifelines 9:512, 509-11. 2005
  41. ncbi Acute effects of selective fetoscopic laser photocoagulation on recipient cardiac function in twin-twin transfusion syndrome
    Mounira Habli
    Fetal Care Center of Cincinnati, Cincinnati Children s Hospital, Cincinnati, OH 45229 3039, USA
    Am J Obstet Gynecol 199:412.e1-6. 2008
    ..This study evaluated the acute effects of selective fetoscopic laser photocoagulation (SFLP) on recipient cardiovascular function in a twin-twin transfusion syndrome (TTTS) pregnancy...
  42. ncbi Pseudoamniotic band syndrome: a rare complication of monochorionic twins with fetofetal transfusion syndrome treated by laser coagulation
    Norbert Winer
    Department of Obstetrics and Gynecology, Université Paris Ouest Versailles St Quentin, Centre Hospitalier Intercommunal Poissy St Germain, Poissy, France
    Am J Obstet Gynecol 198:393.e1-5. 2008
    ....
  43. ncbi Twin-to-twin transfusion syndrome: expanding the frontiers of ignorance?
    D W Skupski
    Ultrasound Obstet Gynecol 31:487-8. 2008
  44. ncbi Fetoscopic laser treatment of twin-to-twintransfusion syndrome (TTTS)
    S Said
    Ir Med J 101:191-3. 2008
    ..Fetoscopic laser ablation of placental vessels for severe twin-to-twin transfusion syndrome is now available in Ireland, and our programme has delivered results that are in keeping with international best practices in this regard...
  45. doi Power and interpretation of a randomized study on the treatment of severe twin-to-twin transfusion syndrome
    Francois I Luks
    Am J Obstet Gynecol 198:607; author reply 607-8. 2008
  46. ncbi [Twin-twin transfusion syndrome--front line in fetal medicine]
    S Ek
    Huddinge Universitetssjukhus, Kvinnokliniken
    Ugeskr Laeger 163:5987-90. 2001
    ..The outcome seems very promising with overall survival of 80% using this method. In the article pathogenesis and alternative treatments are also discussed...
  47. ncbi Stage-related outcome in twin-twin transfusion syndrome treated by fetoscopic laser coagulation
    Agnes Huber
    Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg Eppendorf, UKE, Hamburg, Germany
    Obstet Gynecol 108:333-7. 2006
    ..To assess perinatal outcome in monochorionic twin pregnancies according to different stages of severe mid-trimester twin-twin transfusion syndrome managed by fetoscopic laser coagulation of the placental vascular anastomoses...
  48. ncbi The outcome of twin-twin transfusion syndrome complicated with placental insufficiency
    Mounira Habli
    Fetal Care Center of Cincinnati, Cincinnati Children s Hospital, University Hospital, Cincinnati, OH 45229 3039, USA
    Am J Obstet Gynecol 199:424.e1-6. 2008
    ..The aim was to evaluate the incidence and perinatal outcomes of TTTS complicated with placental insufficiency (PI/TTTS)...
  49. ncbi Operative fetoscopy via telesurgery
    R A Quintero
    Florida Institute for Fetal Diagnosis and Therapy, Tampa, Florida 33613, USA
    Ultrasound Obstet Gynecol 20:390-1. 2002
    We describe a case in which telesurgical consultation from Tampa, Florida, USA was used to accomplish operative fetoscopy in Santiago, Chile for the treatment of a twin pregnancy involving an acardiac twin...
  50. ncbi The treatment of twin-twin transfusion syndrome
    Timothy M Crombleholme
    The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Semin Pediatr Surg 12:175-81. 2003
    ....
  51. ncbi Impact of laser coagulation in severe twin-twin transfusion syndrome on fetal Doppler indices and venous blood flow volume
    E Gratacos
    Fetal Medicine Unit, Department of Obstetrics and Gynaecology, Hospital Vall d Hebron, Universitat Autonoma de Barcelona, Spain
    Ultrasound Obstet Gynecol 20:125-30. 2002
    ....
  52. ncbi Impact of fetal intervention on postnatal management of congenital diaphragmatic hernia
    L Saura
    Agrupació Sanitària Hospital, Sant Joan de Déu Clínic, Universitat de Barcelona, Passeig Sant Joan de Déu 2, Esplugues, Barcelona, Spain
    Eur J Pediatr Surg 17:404-7. 2007
    ..We report our experience in the postnatal management of congenital diaphragmatic hernia (CDH) after fetal endoluminal balloon tracheal occlusion (FETO)...
  53. ncbi Fetal surgery
    Shaun M Kunisaki
    Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Intensive Care Med 23:33-51. 2008
    ..the authors discuss the prenatal evaluation process and various operative approaches (ie, open hysterotomy, fetoscopy, and percutaneous) to conduct fetal surgery...
  54. ncbi Update on twin-to-twin transfusion syndrome
    A El Kateb
    Department of Obstetrics and Gynecology, Paris Ouest Medical School, UVSQ, CHI Poissy Saint Germain en Laye, Paris, France
    Best Pract Res Clin Obstet Gynaecol 22:63-75. 2008
    ..Selectivity in laser coagulation improves survival. Selective feticide should be reserved for cases in which severe distress or anomaly of one twin compromises the others...
  55. ncbi Antenatal intervention: jeopardizing life or limb?
    John M Gatti
    Division of Pediatric Urology, Children s Mercy Hospital and University of Kansas School of Medicine, Kansas City, Missouri 66211, USA
    Urology 60:697. 2002
    ..Although the limb was intact, we present images and a discussion of the potential for extremity injury with antenatal urologic intervention...
  56. ncbi Changes in the approach for invasive prenatal diagnosis in 35,127 cases at a single center from 1977 to 2004
    Giovanni Monni
    Department of Obstetrics and Gynecology, Prenatal and Preimplantation Genetic Diagnosis, Fetal Therapy, Ospedale Microcitemico, Cagliari, Italy
    Fetal Diagn Ther 21:348-54. 2006
    ..To evaluate the changes in the approaches used for invasive prenatal diagnosis for beta-thalassemia and karyotyping at a single center from 1977 to 2004...
  57. ncbi An aggressive interventional protocol for early midtrimester premature rupture of the membranes using gelatin sponge for cervical plugging
    John M O'Brien
    Perinatal Diagnostic Center, Central Baptist Hospital, Lexington, KY 40503, USA
    Am J Obstet Gynecol 187:1143-6. 2002
    ..This study was performed to evaluate a protocol for treatment of previable premature rupture of membranes (PROM) that includes the administration of gelatin sponge to retard the loss of fluid from the amniotic cavity...
  58. ncbi Prenatal diagnosis of cloacal anomalies
    S Warne
    Department of Paediatric Urology, Guy s Hospital and Great Ormond Street Children s Hospital, London, UK
    BJU Int 89:78-81. 2002
    ....
  59. ncbi Laparoscopy-assisted fetoscopy for laser surgery in twin-twin transfusion syndrome with anterior placentation
    R Papanna
    Texas Children s Fetal Center, Baylor College of Medicine, Houston, TX 77030, USA
    Ultrasound Obstet Gynecol 35:65-70. 2010
    ..To compare a laparoscopy-assisted fetoscopic approach with an ultrasound-directed percutaneous approach for laser photocoagulation of placental anastomoses in cases of twin-twin transfusion syndrome (TTTS) with anterior placentation...
  60. ncbi Moving up the slippery slope: mandated genetic screening on Cyprus
    Ruth Schwartz Cowan
    History and Sociology of Science, University of Pennsylvania, 249 S 36th Street, Philadelphia, PA 19104 6304, USA
    Am J Med Genet C Semin Med Genet 151:95-103. 2009
    ..program involves mandated premarital carrier screening, voluntary prenatal diagnosis (originally through fetoscopy, now through CVS), and voluntary termination of afflicted pregnancies-all at public expense...
  61. ncbi Hypohidrotic ectodermal dysplasia: prenatal diagnosis by three-dimensional ultrasonography
    Waldo Sepulveda
    Fetal Medicine Center, Department of Obstetrics and Gynecology, Clinica Las Condes, Santiago, Chile
    J Ultrasound Med 22:731-5. 2003
    ..in high-risk pregnancies on the basis of histologic analysis of fetal skin obtained by second-trimester fetoscopy-guided skin biopsy...
  62. ncbi Prenatal diagnosis of spontaneous septostomy of the dividing membranes in complicated monochorionic diamniotic multiple gestations
    Ramen H Chmait
    Department of Obstetrics and Gynecology, University of Southern California Keck School of Medicine, Los Angeles, CA 90027, USA
    J Ultrasound Med 28:663-8. 2009
    ..The purpose of this series is to describe the prenatal diagnostic and management challenges of spontaneous septostomy of the dividing membrane (SSDM) in complicated monochorionic diamniotic (MoDi) pregnancies...
  63. ncbi Alcoholization: the choice of intrauterine treatment for chorioangioma
    Chanane Wanapirak
    Department of Obstetrics and Gynecology, Faculty of Medicine, Chiang Mai University, Thailand
    J Obstet Gynaecol Res 28:71-5. 2002
    ..To our knowledge, this is the first report using alcoholization for the treatment of hydrops fetalis secondary to chorioangioma...
  64. ncbi Severe diaphragmatic hernia treated by fetal endoscopic tracheal occlusion
    J C Jani
    Fetal Medicine and Treatment Unit of University Hospital Gasthuisberg, Leuven, Belgium
    Ultrasound Obstet Gynecol 34:304-10. 2009
    ..To examine operative and perinatal aspects of fetal endoscopic tracheal occlusion (FETO) in congenital diaphragmatic hernia (CDH)...
  65. ncbi Fetoscopic surgery for the treatment of congenital anomalies
    J M Estes
    Department of Surgery, University of California, San Francisco 94143 0570
    J Pediatr Surg 27:950-4. 1992
    ..As a consequence, the potential now exists to correct non-life-threatening malformations in utero...
  66. ncbi Direct visual control on cord coagulation using a fetoscopy-guided bipolar forceps. Description of a new technique
    Masami Yamamoto
    Department of Obstetrics and Gynecology, Groupe Hospitalier, Necker Enfants Malades, Universite Paris Descartes, 149, rue de Sevres, 75743 Paris Cedex 15, Paris, France
    Prenat Diagn 30:156-8. 2010
    ..We describe a new technique to achieve permanent umbilical cord occlusion...
  67. ncbi [Intrauterine fetal abnormalities therapy]
    Lourenco Sbragia
    Divisão de Cirurgia Pediátrica, Departamento de Cirurgia e Anatomia, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo, Ribeirao Preto, SP, Brasil
    Rev Bras Ginecol Obstet 32:47-54. 2010
    ..experimental studies in large animals, associated with the technological advance of diagnostic imaging and fetoscopy equipment, have led to great progress in the knowledge of the pathophysiology of various congenital defects...
  68. ncbi Laser therapy of twin-to-twin transfusion syndrome in triplet pregnancies
    A Diemert
    Department of Obstetrics and Fetal Medicine, University Medical Center Hamburg Eppendorf, Hamburg, Germany
    Ultrasound Obstet Gynecol 35:71-4. 2010
    ..We report the outcome of triplet pregnancies treated with laser therapy for severe TTTS...
  69. ncbi Twin anemia polycythemia sequence from a prenatal perspective
    Leonardo Gucciardo
    Department of Obstetrics and Gynecology, University Hospitals, Leuven, Belgium
    Prenat Diagn 30:438-42. 2010
    ..To describe the prevalence, management and outcome of spontaneous twin anemia polycythemia sequence (TAPS) diagnosed in the prenatal period...
  70. ncbi Selective feticide in monoamniotic twin pregnancies by umbilical cord occlusion and transection
    Johanna M Middeldorp
    Department of Obstetrics, Leiden University Medical Centre, Leiden, The Netherlands
    Fetal Diagn Ther 23:121-5. 2008
    ..However, the normal co-twin remains at risk of sudden demise from cord entanglement. We report on three cases of successful selective feticide by cord occlusion combined with cord transection...
  71. pmc The clinical spectrum of the Fraser syndrome: report of three new cases and review
    J Gattuso
    Department of Clinical Genetics, Institute of Child Health, London
    J Med Genet 24:549-55. 1987
    ..variability should be taken into account when attempting prenatal diagnosis; a combination of ultrasound and fetoscopy should provide the best approach...
  72. ncbi Efficacy of electrocautery in different media: air, perfluorodecalin, glycerine, glycine, and electrolyte solution
    Oliver J Muensterer
    Department of Pediatric Surgery, University of Leipzig, Leipzig, Germany
    J Laparoendosc Adv Surg Tech A 16:659-62. 2006
    ..Intrauterine insufflation of carbon dioxide may cause lethal hypercapnia and acidosis in the fetus. Therefore, other media must be considered...
  73. ncbi Fetoscopic management of complicated monochorionic twins
    Ramen Chmait
    Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Clin Obstet Gynecol 52:647-53. 2009
    Operative fetoscopy is a surgical approach to the in utero treatment of fetal or placental abnormalities. The approach is on the basis of combined use of ultrasound and endoscopy and minimally invasive access into the womb...
  74. ncbi Clinical and biochemical predictors of very preterm birth in twin-to-twin transfusion syndrome treated by fetoscopy
    Teresa Cobo
    Department of Maternal Fetal Medicine, Hospital Clinic, Institute Clinic of Gynecology, Obstetrics, and Neonatology, Barcelona, Spain
    Am J Obstet Gynecol 204:58.e1-5. 2011
    ..To evaluate pre- and postoperative predictors of preterm birth in twin-to-twin transfusion syndrome treated with fetoscopic placental laser coagulation...
  75. ncbi Gelatin sponge embolization. a method for the management of iatrogenic preterm premature rupture of the membranes
    John M O'Brien
    Department of Maternal Fetal Medicine at Central Baptist Hospital, Lexington, KY 40503, USA
    Fetal Diagn Ther 17:8-10. 2002
    ..A successful case of embolization for the treatment of iatrogenic previable PROM complicating therapeutic fetoscopy is described.
  76. ncbi Optical properties of human amniotic fluid: implications for videofetoscopic surgery
    Shaun A Steigman
    Department of Surgery, Children s Hospital Boston, MA, USA
    Fetal Diagn Ther 27:87-90. 2010
    ..We sought to determine the optical properties of the amniotic fluid, as a pre-requisite for optimizing video image processing during videofetoscopy and eventually avoid amniotic fluid replacement...
  77. ncbi Toward fetal therapy using needle embryofetoscopy
    E A Reece
    Department of Obstetrics, Gynecology and Reproductive Sciences, Temple University School of Medicine, Haifa, Israel
    Ultrasound Obstet Gynecol 5:281-5. 1995
    ..Potential applications include gene and stem-cell therapy at a time when the embryo is immunologically naive...
  78. ncbi Selective fetoscopic laser ablation in 100 consecutive pregnancies with severe twin-twin transfusion syndrome
    Robert B Cincotta
    Department of Maternal Fetal Medicine, Mater Mothers Hospital, South Brisbane, Queensland, Australia
    Aust N Z J Obstet Gynaecol 49:22-7. 2009
    ....
  79. ncbi Life-saving effects of fetal tracheal occlusion on pulmonary hypoplasia from preterm premature rupture of membranes
    Thomas Kohl
    Department of Obstetrics and Prenatal Medicine German Center for Fetal Surgery and Minimally Invasive Therapy, Munster, Germany
    Obstet Gynecol 113:480-3. 2009
    ..Preterm premature rupture of membranes before 22 weeks of gestation may result in severe fetal pulmonary hypoplasia. Fetoscopic tracheal balloon occlusion might result in catch-up pulmonary growth...
  80. ncbi Transitory increase in middle cerebral artery peak systolic velocity of recipient twins after fetoscopic laser photocoagulation for twin-twin transfusion syndrome
    Keisuke Ishii
    Division of Perinatology, Fetal Diagnosis and Therapy, Maternal and Perinatal Care Center, Seirei Hamamatsu General Hospital, Hamamatsu, Japan
    Fetal Diagn Ther 24:470-3. 2008
    ..It was the aim of this study to elucidate the clinical features of recipient twins with increased middle cerebral artery peak systolic velocity (MCA-PSV) after fetoscopic laser photocoagulation (FLP) for twin-twin transfusion syndrome...
  81. ncbi [What's new in fetal medicine?]
    D Mahieu-Caputo
    Service de Gynecologie Obstetrique, Hopital Bichat, Paris, France
    Arch Pediatr 9:172-86. 2002
    ..All this underscores that fetal medicine is no longer solely a succession of dramatic technical breakthroughs, but is entered an era of large-scale diffusion that requires evidence based evaluation...
  82. ncbi Antenatal prediction of lung volume and in-utero treatment by fetal endoscopic tracheal occlusion in severe isolated congenital diaphragmatic hernia
    Jan A Deprest
    Center for Surgical Technologies, Faculty of Medicine, Katholieke Universiteit Leuven, Minderbroedersstraat 17, B 3000 Leuven, Belgium
    Semin Fetal Neonatal Med 14:8-13. 2009
    ..The purpose of this review is to update current knowledge regarding predictive value of prenatal assessment in terms of neonatal survival. We will also discuss experimental evidence and clinical data regarding fetal tracheal occlusion...
  83. ncbi Twin-twin transfusion syndrome: the 'Select' procedure
    V A Feldstein
    Fetal Treatment Program and Department of Radiology, University of California, San Francisco, Calif 94143 0628, USA
    Fetal Diagn Ther 15:257-61. 2000
    ..We report here a case of early, severe TTTS that failed to respond to serial amniocenteses and that was successfully treated by means of superselective laser coagulation...
  84. ncbi Endoscopic laser coagulation of placental anastomoses in 200 pregnancies with severe mid-trimester twin-to-twin transfusion syndrome
    K Hecher
    Department of Prenatal Diagnosis and Therapy, AK Barmbek, D 22291, Hamburg, Germany
    Eur J Obstet Gynecol Reprod Biol 92:135-9. 2000
    ..To investigate perinatal outcome after endoscopic laser coagulation of the placental vascular anastomoses in severe mid trimester twin-to-twin transfusion syndrome (TTTS)...
  85. ncbi Fetoscopic direct fetal cardiac access in sheep : An important experimental milestone along the route to human fetal cardiac intervention
    T Kohl
    Department of Pediatric Cardiology, University of Munster Medical School, Munster, Germany
    Circulation 102:1602-4. 2000
    ..Therefore, the purpose of our study in sheep was to assess the feasibility and potential of fetoscopic direct fetal cardiac access...
  86. ncbi Embryonic and neonatal cardiac gene transfer in vivo
    Geir Christensen
    Institute for Experimental Medical Research, University of Oslo, Ullevaal University Hospital, Norway
    Methods Mol Biol 219:169-78. 2003
  87. ncbi Chorioamnion plugging and the risk of preterm premature rupture of membranes after laser surgery in twin-twin transfusion syndrome
    R Papanna
    The Texas Children s Fetal Center at Texas Children s Hospital, Division of Maternal Fetal Medicine, Department of Obstetrics and Gynecology, Baylor College of Medicine, Houston, Texas 77030, USA
    Ultrasound Obstet Gynecol 35:337-43. 2010
    ....
  88. ncbi Diagnosis and management of fetal intrapericardial Morgagni diaphragmatic hernia with massive pericardial effussion
    Guillermo Antinolo
    Unidad de Gestión Clínica de Genética, Reproducción y Medicina Fetal, Hospitales Universitarios Virgen del Rocio, 41013 Sevilla, Spain
    J Pediatr Surg 45:424-6. 2010
    ..After birth, the patient successfully underwent early correction of the hernia. Postoperative course was uneventful, and the newborn girl was discharged 18 days later without complications and is currently doing well...
  89. ncbi Laser therapy for twin-twin transfusion syndrome in the absence of fetoscopically visible placental vascular anastomoses
    Keisuke Ishii
    Department of Maternal Fetal Medicine, Osaka Medical Center and Research Institute for Maternal and Child Health, Izumi, Japan
    Fetal Diagn Ther 34:192-4. 2013
    ..This case demonstrates that vascular anastomoses in TTTS may not be identified by a fetoscope and that FLP to coagulate the entire vascular equator closer to the area of the recipient twin was effective in this rare situation...
  90. ncbi [Disputes and history of fetal heart monitoring]
    Omar Felipe Duenas-Garcia
    Departamento de Ginecologíia y Obstetricia del Hospital Bronx Lebanon Center, New York City 10457, USA
    Rev Invest Clin 63:659-63. 2011
    ..The purpose of this article is to mention the key points and controversial moments in the history of the cardiotocography..
  91. ncbi Predictors of neonatal morbidity in fetuses with severe isolated congenital diaphragmatic hernia undergoing fetoscopic tracheal occlusion
    E Done
    Department of Obstetrics and Gynaecology, Division of Woman and Child, University Hospitals Leuven, Leuven, Belgium
    Ultrasound Obstet Gynecol 42:77-83. 2013
    ....
  92. ncbi Management of prenatally diagnosed congenital diaphragmatic hernia
    Holly L Hedrick
    Perelman School of Medicine at the University of Pennsylvania, The Center for Fetal Diagnosis and Treatment, Children s Hospital of Philadelphia, Philadelphia, PA 19104, USA
    Semin Pediatr Surg 22:37-43. 2013
    ..The increased survival and subsequent morbidity of CDH survivors has resulted in the need to provide resources for the long-term follow up and support of the CDH population...
  93. ncbi Hypoalbuminemia in donors with twin-twin transfusion syndrome
    L Verbeek
    Division of Neonatology, Willem Alexander Children s Hospital, Leiden, The Netherlands
    Fetal Diagn Ther 33:98-102. 2013
    ..To estimate the differences in albumin levels between donors and recipients with twin-twin transfusion syndrome (TTTS)...
  94. ncbi Fetoscopic laser therapy for twin-twin transfusion syndrome before 17 and after 26 weeks' gestation
    David Baud
    Fetal Medicine Unit, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada
    Am J Obstet Gynecol 208:197.e1-7. 2013
    ....
  95. ncbi Antenatal management of isolated congenital diaphragmatic hernia today and tomorrow: ongoing collaborative research and development. Journal of Pediatric Surgery Lecture
    Jan Deprest
    Division of Woman and Child, Department of Reproduction, Development, and Regeneration, University Hospitals Leuven, 3000 Leuven, Belgium
    J Pediatr Surg 47:282-90. 2012
    ..Fetuses with severe hypoplasia usually require postnatal operative repair using prosthetic patches, and tissue engineering offers the potential for ex utero culture...
  96. ncbi Neonatal outcome using ultrathin fetoscope for laser coagulation in twin-to-twin-transfusion syndrome
    Michael Tchirikov
    University Clinic of Obstetrics and Fetal Medicine, University Medical Center Halle Saale of Martin Luther University of Halle Wittenberg, Germany
    J Perinat Med 39:725-30. 2011
    ..To improve neonatal outcome using ultrathin fetoscope for laser treatment of twin-to-twin transfusion syndrome...
  97. ncbi Fetoscopic coverage of experimental myelomeningocele in sheep using a patch with surgical sealant
    Cesar G Fontecha
    Paediatric Orthopaedic Surgery Unit, Vall d Hebron University Hospital, Barcelona, Spain
    Eur J Obstet Gynecol Reprod Biol 156:171-6. 2011
    ..Assess the feasibility of a fetoscopic patch coverage method for myelomeningocele repair in a sheep model...
  98. ncbi Design of a flexible fetoscopy manipulation system for congenital diaphragmatic hernia
    Wei Yao
    Department of Biomedical Engineering, The University of Strathclyde, Glasgow, United Kingdom Electronic address
    Med Eng Phys 36:32-8. 2014
    ..Experiments using a phantom have demonstrated that the flexible fetoscope has a better dexterity and is able to perform stable tracheoscopy and balloon inflation at different levels of the trachea, with the help of a fiberoptic camera. ..
  99. ncbi [Congenital anomalies of the central nervous system--from the pediatric standpoint]
    K Kumagai
    Department of Pediatrics, Kanagawa Rehabilitation Center
    No To Hattatsu 23:177-82. 1991
    ..With recent advances in the diagnostic techniques of amniocentesis, fetoscopy, ultrasound, computerized tomography (CT) and magnetic resonance imaging (MRI), an improved accuracy in the ..
  100. ncbi Cross-sectional study of tracheomegaly in children after fetal tracheal occlusion for severe congenital diaphragmatic hernia
    Luc Breysem
    Department of Radiology, University Hospitals Leuven, Herestraat 49, Leuven, Belgium
    Radiology 257:226-32. 2010
    ..To measure tracheal dimensions in children with congenital diaphragmatic hernia (CDH) who had undergone fetoscopic endoluminal tracheal occlusion (FETO) or were treated expectantly during gestation...
  101. ncbi Fetoscopic laser coagulation for severe twin-to-twin transfusion syndrome: factors influencing perinatal outcome, learning curve of the procedure and lessons for new centres
    R K Morris
    School of Clinical and Experimental Medicine, University of Birmingham, Edgbaston, Birmingham, UK
    BJOG 117:1350-7. 2010
    ..To evaluate the effects of operator experience on perinatal outcome in a single centre...

Research Grants7

  1. Miniature Laser Therapy Endoscope
    Guillermo Tearney; Fiscal Year: 2009
    ..However, current fetoscopy technology used to guide this procedure is not adequate for this application...
  2. DERMAL-EPIDERMAL INTERACTIONS IN DIABETIC WOUND HEALING
    Timothy Crombleholme; Fiscal Year: 2004
    ..abstract_text> ..
  3. Twin-Twin Transfusion Syndrome Trial
    Timothy Crombleholme; Fiscal Year: 2004
    ..The overall goal of the study is to improve the outcomes of twins with TTTS by determining which treatment for TTTS has a better survival as well as cardiac, neurologic, and developmental outcome. ..
  4. Endothelial Progenitor Cell Recruitment in Diabetic Mice
    Timothy Crombleholme; Fiscal Year: 2008
    ..To determine the mechanisms by which EPCs orchestrate the local angiogenic response by interaction with resident cellular milieu. ..
  5. Endothelial Progenitor Cell Biology in Type 1 Diabetes
    Timothy Crombleholme; Fiscal Year: 2008
    ..3. To determine the mechanisms by which type I diabetes alters EPC gene expression and function. ..
  6. Mechanisms of Scar-Free Healing in the Fetal Artery
    DARRELL CASS; Fiscal Year: 2008
    ..His long term objective is to apply this knowledge clinically in both children and adults to limit vascular inflammation, neointimal hyperplasia and scarring. [unreadable] [unreadable] [unreadable]..
  7. UROTHELIAL DIFFENTIATION
    Laurence Baskin; Fiscal Year: 2003
    ..Furthermore, we propose that abnormal epithelial-stroma signaling that occurs when intestinal segments are placed in contact with the bladder may lead to cellular changes such as atypia or even cancer. ..