transcutaneous electric nerve stimulation

Summary

Summary: The use of specifically placed small electrodes to deliver electrical impulses across the SKIN to relieve PAIN. It is used less frequently to produce ANESTHESIA.

Top Publications

  1. ncbi Effects of TENS frequency, intensity and stimulation site parameter manipulation on pressure pain thresholds in healthy human subjects
    Linda S Chesterton
    Department of Physiotherapy Studies, Keele University, Staffordshire ST5 5BG, UK
    Pain 106:73-80. 2003
  2. ncbi Effectiveness of transcutaneous electrical nerve stimulation and interferential current in primary dysmenorrhea
    Nazan Tugay
    Department of Physiotherapy and Rehabilitation, Mugla School of Health Sciences, Mugla University, Mugla, Turkey
    Pain Med 8:295-300. 2007
  3. ncbi Transcutaneous electrical nerve stimulation: basic science mechanisms and clinical effectiveness
    Kathleen A Sluka
    Physical Therapy and Rehabilitation Sciences Graduate Program, Neuroscience Graduate Program, Pain Research Program, University of Iowa, Iowa City, IA 52242, USA
    J Pain 4:109-21. 2003
  4. ncbi Dose-specific effects of transcutaneous electrical nerve stimulation (TENS) on experimental pain: a systematic review
    Leica S Claydon
    School of Physiotherapy, Centre for Physiotherapy Research, University of Otago, Dunedin, New Zealand
    Clin J Pain 27:635-47. 2011
  5. pmc A new transient sham TENS device allows for investigator blinding while delivering a true placebo treatment
    Barbara Rakel
    University of Iowa, College of Nursing, Iowa City, Iowa
    J Pain 11:230-8. 2010
  6. ncbi Transcutaneous electrical nerve stimulation for the management of painful conditions: focus on neuropathic pain
    Mark I Johnson
    Faculty of Health and Social Sciences, Leeds Metropolitan University, Leeds, LS1 3HE, UK
    Expert Rev Neurother 11:735-53. 2011
  7. ncbi Hypoalgesia in response to transcutaneous electrical nerve stimulation (TENS) depends on stimulation intensity
    Fidelma Moran
    Health and Rehabilitation Sciences Research Institute, University of Ulster, United Kingdom
    J Pain 12:929-35. 2011
  8. ncbi A model for transcutaneous current stimulation: simulations and experiments
    Andreas Kuhn
    Automatic Control Laboratory, ETH Zurich, Physikstrasse 3, 8092 Zurich, Switzerland
    Med Biol Eng Comput 47:279-89. 2009
  9. ncbi Spinal cord stimulation for axial low back pain: a prospective, controlled trial comparing dual with single percutaneous electrodes
    Richard B North
    Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287 7881, USA
    Spine (Phila Pa 1976) 30:1412-8. 2005
  10. pmc Effectiveness of transcutaneous electrical nerve stimulation for treatment of hyperalgesia and pain
    Josimari M Desantana
    Department of Physical Therapy, Federal University of Sergipe, Av Marechal Rondon, Jardim Rosa Elze, Sao Cristovao, Sergipe, Brasil 491000
    Curr Rheumatol Rep 10:492-9. 2008

Detail Information

Publications264 found, 100 shown here

  1. ncbi Effects of TENS frequency, intensity and stimulation site parameter manipulation on pressure pain thresholds in healthy human subjects
    Linda S Chesterton
    Department of Physiotherapy Studies, Keele University, Staffordshire ST5 5BG, UK
    Pain 106:73-80. 2003
    ..All other TENS intervention groups showed hypoalgesic responses similar to the sham TENS group, and none of these groups reached a clinically significant hypoalgesic level...
  2. ncbi Effectiveness of transcutaneous electrical nerve stimulation and interferential current in primary dysmenorrhea
    Nazan Tugay
    Department of Physiotherapy and Rehabilitation, Mugla School of Health Sciences, Mugla University, Mugla, Turkey
    Pain Med 8:295-300. 2007
    ..To compare the effectiveness of transcutaneous electrical nerve stimulation and interferential current in primary dysmenorrhea...
  3. ncbi Transcutaneous electrical nerve stimulation: basic science mechanisms and clinical effectiveness
    Kathleen A Sluka
    Physical Therapy and Rehabilitation Sciences Graduate Program, Neuroscience Graduate Program, Pain Research Program, University of Iowa, Iowa City, IA 52242, USA
    J Pain 4:109-21. 2003
    ..However, the clinical efficacy of TENS will remain equivocal until the publication of sufficient numbers of high quality, randomized, controlled clinical trials...
  4. ncbi Dose-specific effects of transcutaneous electrical nerve stimulation (TENS) on experimental pain: a systematic review
    Leica S Claydon
    School of Physiotherapy, Centre for Physiotherapy Research, University of Otago, Dunedin, New Zealand
    Clin J Pain 27:635-47. 2011
    ..To determine the hypoalgesic effects of transcutaneous electrical nerve stimulation (TENS) parameter combinations on experimental models in healthy humans...
  5. pmc A new transient sham TENS device allows for investigator blinding while delivering a true placebo treatment
    Barbara Rakel
    University of Iowa, College of Nursing, Iowa City, Iowa
    J Pain 11:230-8. 2010
    ..HPTs and pain intensities to tonic heat were not significantly changed. The transient TENS completely blinds investigators to treatment and does not reduce pain, thereby providing a true placebo treatment...
  6. ncbi Transcutaneous electrical nerve stimulation for the management of painful conditions: focus on neuropathic pain
    Mark I Johnson
    Faculty of Health and Social Sciences, Leeds Metropolitan University, Leeds, LS1 3HE, UK
    Expert Rev Neurother 11:735-53. 2011
    ..The use of electrode arrays to spatially target stimulation more precisely may improve the efficacy of TENS in the future...
  7. ncbi Hypoalgesia in response to transcutaneous electrical nerve stimulation (TENS) depends on stimulation intensity
    Fidelma Moran
    Health and Rehabilitation Sciences Research Institute, University of Ulster, United Kingdom
    J Pain 12:929-35. 2011
    ..33, P = .003). These data therefore show that there is a dose-response effect of TENS with the largest effect occurring with the highest current amplitudes...
  8. ncbi A model for transcutaneous current stimulation: simulations and experiments
    Andreas Kuhn
    Automatic Control Laboratory, ETH Zurich, Physikstrasse 3, 8092 Zurich, Switzerland
    Med Biol Eng Comput 47:279-89. 2009
    ..The presented TES model provides a first step to more extensive model implementations for TES in which e.g., multi-array electrode configurations can be tested...
  9. ncbi Spinal cord stimulation for axial low back pain: a prospective, controlled trial comparing dual with single percutaneous electrodes
    Richard B North
    Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287 7881, USA
    Spine (Phila Pa 1976) 30:1412-8. 2005
    ..A prospective, controlled, clinical trial comparing single and dual percutaneous electrodes in the treatment of axial low back pain from failed back surgery syndrome...
  10. pmc Effectiveness of transcutaneous electrical nerve stimulation for treatment of hyperalgesia and pain
    Josimari M Desantana
    Department of Physical Therapy, Federal University of Sergipe, Av Marechal Rondon, Jardim Rosa Elze, Sao Cristovao, Sergipe, Brasil 491000
    Curr Rheumatol Rep 10:492-9. 2008
    ..Thus, evidence continues to emerge from both basic science and clinical trials supporting the use of TENS for the treatment of a variety of painful conditions while identifying strategies to increase TENS effectiveness...
  11. ncbi Spinal blockade of opioid receptors prevents the analgesia produced by TENS in arthritic rats
    K A Sluka
    Neuroscience Graduate Program, The University of Iowa, Iowa City, Iowa, USA
    J Pharmacol Exp Ther 289:840-6. 1999
    ..Thus, low-frequency TENS produces antihyperalgesia through mu opioid receptors and high-frequency TENS produces antihyperalgesia through delta opioid receptors in the spinal cord...
  12. ncbi Effectiveness of transcutaneous electrical nerve stimulation on postoperative pain with movement
    Barbara Rakel
    Department of Nursing Services and Patient Care, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
    J Pain 4:455-64. 2003
    ..The lack of effect on pain at rest supports the hypothesis that TENS works through reducing hyperalgesia...
  13. ncbi Adjusting pulse amplitude during transcutaneous electrical nerve stimulation (TENS) application produces greater hypoalgesia
    Manuela A Pantaleão
    University of the City of Sao Paulo UNICID, Physical Therapy Department, Sao Paulo, Brazil
    J Pain 12:581-90. 2011
    ..The mean final pulse amplitude for the adjusted pulse amplitude TENS group was 35.51 mA when compared to the fixed pulse amplitude TENS group, which averaged 31.37 mA (P = .0318)...
  14. pmc An investigation of the development of analgesic tolerance to TENS in humans
    Richard E Liebano
    University of the City of Sao Paulo, Physical Therapy Department, Sao Paulo, Brazil
    Pain 152:335-42. 2011
    ..Repeated high-frequency and low-frequency transcutaneous electrical nerve stimulation produce analgesic tolerance in humans by the fourth and fifth day of treatment, respectively...
  15. ncbi Blockade of opioid receptors in rostral ventral medulla prevents antihyperalgesia produced by transcutaneous electrical nerve stimulation (TENS)
    A Kalra
    Physical Therapy Graduate Program, College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
    J Pharmacol Exp Ther 298:257-63. 2001
    ..Hence, low-frequency and high-frequency TENS produces antihyperalgesia by activation of mu- and delta-opioid receptors, respectively, in the RVM...
  16. ncbi High and low frequency TENS reduce postoperative pain intensity after laparoscopic tubal ligation: a randomized controlled trial
    Josimari M Desantana
    Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, IA, USA
    Clin J Pain 25:12-9. 2009
    ..Therefore, we studied the effects of TENS on postoperative pain after LS through placement of Yoon fallopian rings in a prospective, randomized, double-blinded, and placebo-controlled study...
  17. ncbi Effects of intensity of Transcutaneous Electrical Nerve Stimulation (TENS) on pressure pain threshold and blood pressure in healthy humans: A randomized, double-blind, placebo-controlled trial
    Lazaros Lazarou
    Department of Physical Education and Sports Science, Aristotle University, Thessaloniki, Greece
    Clin J Pain 25:773-80. 2009
    ..The purpose of this study was to investigate the comparative effects of 2 intensities on pressure pain threshold (PPT) and resting BP in healthy humans, using low-frequency stimulation applied segmentally to the pain site...
  18. ncbi The future of peripheral nerve stimulation
    Michael Stanton-Hicks
    Pain Management Department, Center for Neurological Restoration, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Prog Neurol Surg 24:210-7. 2011
    ....
  19. ncbi Comparison of continuous and intermittent transcutaneous electrical nerve stimulation in postoperative pain management after coronary artery bypass grafting: a randomized, placebo-controlled prospective study
    Ozlem Solak
    Department of Physical Medicine and Rehabilitation, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey
    Heart Surg Forum 12:E266-71. 2009
    ..We compared the effectiveness of continuous transcutaneous electrical nerve stimulation (TENS) and intermittent TENS in the management of pain after coronary artery bypass grafting (CABG)...
  20. ncbi Applications of neurostimulation for urinary storage and voiding dysfunction in neurological patients
    F S Van Rey
    Department of Urology, the Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Urol Int 81:373-8. 2008
    ..We review the utilization and the results of electrical stimulation by means of pudendal nerve stimulation, stimulation of the sacral nerve roots and lower limb stimulation in patients with neurogenic detrusor overactivity...
  21. ncbi Does four weeks of TENS and/or isometric exercise produce cumulative reduction of osteoarthritic knee pain?
    Gladys L Y Cheing
    Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon
    Clin Rehabil 16:749-60. 2002
    ....
  22. ncbi Transcutaneous neuromuscular electrical stimulation: influence of electrode positioning and stimulus amplitude settings on muscle response
    M Gobbo
    Department of Biomedical Sciences and Biotechnologies, University of Brescia, Brescia, Italy
    Eur J Appl Physiol 111:2451-9. 2011
    ..e., comfortable and effective, stimulation to promote the aforementioned muscle adaptive modifications...
  23. ncbi Short-term transcutaneous electrical nerve stimulation after cardiac surgery: effect on pain, pulmonary function and electrical muscle activity
    Gerson Cipriano
    Cardiovascular Surgery Division, Department of Surgery, Federal University of Sao Paulo, Napoleão de Barros, 715, 3rd Floor, 04023 002, Sao Paulo, SP, Brazil
    Interact Cardiovasc Thorac Surg 7:539-43. 2008
    ..05). TENS is a valuable strategy to alleviate postoperative pain following cardiac surgery with positive effects on pulmonary ventilatory function and electrical activity of thoracic and girdle muscles...
  24. ncbi Comparison of three different approaches in the treatment of chronic low back pain
    Sebnem Koldas Dogan
    Department of Physical Medicine and Rehabilitation, Ufuk University School of Medicine, Ankara, Turkey
    Clin Rheumatol 27:873-81. 2008
    ..On the other hand, physical therapy + home exercise was found to be more effective regarding disability and psychological disturbance...
  25. ncbi Osteoarthritis year 2010 in review: non-pharmacologic therapy
    G A Hawker
    Canadian Osteoarthritis Research Program, Women s College Research Institute, Women s College Hospital, University of Toronto, Toronto, ON M5S 1B2, Canada
    Osteoarthritis Cartilage 19:366-74. 2011
    ..To highlight seminal publications in the past year on the topic of non-pharmacologic management of osteoarthritis (OA)...
  26. ncbi Alternating-frequency TENS effects on experimental pain in healthy human participants: a randomized placebo-controlled trial
    Leica S Claydon
    Centre for Physiotherapy Research, University of Otago, Dunedin, New Zealand
    Clin J Pain 29:533-9. 2013
    ..Transcutaneous electrical nerve stimulation (TENS) is a modality commonly used in pain management...
  27. ncbi Electrical stimulation as a modality to improve performance of the neuromuscular system
    Marc Vanderthommen
    Department of Motor Sciences, University of Liege, Brussels, Belgium
    Exerc Sport Sci Rev 35:180-5. 2007
    ..The adaptations evoked by NMES are not confined to the activated muscle but also involve neural adaptations through reflex inputs to the spinal cord and supraspinal centers...
  28. ncbi Increase of the heat pain threshold during and after high-frequency transcutaneous peripheral nerve stimulation in a group of normal subjects
    M Buonocore
    Unit of Clinical Neurophysiology, Salvatore Maugeri Foundation, Scientific Institute of Pavia, Pavia, Italy
    Eura Medicophys 43:155-60. 2007
    ..The aim of the investigation was to verify the hypothesis that HF-TPNS increases the heat pain threshold in the skin territory of the stimulated nerve, during and after stimulation...
  29. ncbi Effect of occlusal splint and transcutaneous electric nerve stimulation on the signs and symptoms of temporomandibular disorders in patients with bruxism
    A Alvarez-Arenal
    University of Oviedo Dental School, Asturias Central Hospital, Spain
    J Oral Rehabil 29:858-63. 2002
    ..random assignment to treatment, with the aim of evaluating the action of an occlusal splint with transcutaneous electric nerve stimulation (TENS) upon the manifestations of temporomandibular disorders (TMD) in patients with bruxism...
  30. ncbi Is mechanical pain threshold after transcutaneous electrical nerve stimulation (TENS) increased locally and unilaterally? A randomized placebo-controlled trial in healthy subjects
    Reidar Aarskog
    Institute of Physiotherapy, Bergen University College, Norway
    Physiother Res Int 12:251-63. 2007
    ..It is not fully understood how transcutaneous electrical nerve stimulation (TENS) intensity affects mechanical pain threshold...
  31. ncbi An investigation into the magnitude of the current window and perception of transcutaneous electrical nerve stimulation (TENS) sensation at various frequencies and body sites in healthy human participants
    Nicola Hughes
    Faculty of Health and Social Sciences, Leeds Metropolitan University, UK
    Clin J Pain 29:146-53. 2013
    ....
  32. pmc Increased release of serotonin in the spinal cord during low, but not high, frequency transcutaneous electric nerve stimulation in rats with joint inflammation
    Kathleen A Sluka
    Physical Therapy and Rehabilitation Science Graduate Program, Neuroscience Graduate Program, Pain Research Program, University of Iowa, Iowa City, 52242, USA
    Arch Phys Med Rehabil 87:1137-40. 2006
    To determine the release pattern of serotonin and noradrenaline in the spinal cord in response to transcutaneous electric nerve stimulation (TENS) delivered at low or high frequency.
  33. ncbi Analgesic effects of transcutaneous electrical nerve stimulation and interferential currents on heat pain in healthy subjects
    Gladys L Y Cheing
    Department of Rehabilitation Sciences, Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong
    J Rehabil Med 35:15-9. 2003
    ..However, the post-stimulation effect of interferential current lasted longer than that of transcutaneous electrical nerve stimulation...
  34. ncbi Value of TENS for relief of chronic low back pain with or without radicular pain
    A Buchmuller
    Centre d investigation Clinique Epidémiologie Clinique Essais Cliniques CIE3, CHU de Saint Etienne, Saint Etienne Cedex, France
    Eur J Pain 16:656-65. 2012
    ..To evaluate the efficacy of transcutaneous electrical neurostimulation (TENS) in patients with chronic low back pain (LBP)...
  35. ncbi Alternating frequencies of transcutaneous electric nerve stimulation: does it produce greater analgesic effects on mechanical and thermal pain thresholds?
    K C Tong
    Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong SAR, China
    Arch Phys Med Rehabil 88:1344-9. 2007
    To determine whether alternating frequency transcutaneous electric nerve stimulation (TENS) at 2 and 100Hz (2/100Hz) has a more potent hypoalgesic effect than a fixed frequency at 2 or 100Hz in healthy participants.
  36. ncbi Effect of transcutaneous electrical nerve stimulation on sensation thresholds in patients with painful diabetic neuropathy: an observational study
    Metka Moharić
    Department of Physical and Rehabilitation Medicine, Linhartova 51, SI 1000 Ljubljana, Slovenia
    Int J Rehabil Res 33:211-7. 2010
    ..TENS did not alter C, Aδ nor Aβ fibre-mediated perception thresholds. The observed changes at thenar are probably because of central mechanisms. In general, analgesic mechanisms of TENS are likely to be complex...
  37. ncbi Transcutaneous electric nerve stimulation reduces neglect-related postural instability after stroke
    D A Perennou
    Départment de Médecine Physique et Réadaptation du CHU de Nîmes, Unite de Reeducation Neurologique, Le Grau du Roi, France
    Arch Phys Med Rehabil 82:440-8. 2001
    ....
  38. ncbi The relationship between dorsal horn neurotransmitter content and allodynia in neuropathic rats treated with high-frequency transcutaneous electric nerve stimulation
    David L Somers
    Department of Physical Therapy, John G Rangos Sr School of Health Sciences, Duquesne University, Pittsburgh, PA 15282 0011, USA
    Arch Phys Med Rehabil 84:1575-83. 2003
    To examine the relation between axon terminal neurotransmitter content in the dorsal horn and allodynia in neuropathic rats treated with high-frequency transcutaneous electric nerve stimulation (TENS).
  39. ncbi Pain reducing effect of three types of transcutaneous electrical nerve stimulation in patients with chronic pain: a randomized crossover trial
    Albere J A Koke
    Pain Management and Research Center, University Hospital Maastricht, Maastricht, The Netherlands
    Pain 108:36-42. 2004
    ..Because no placebo group was included, no definite conclusions on effectiveness of TENS in general in the treatment of chronic pain could be made...
  40. ncbi Subcutaneous peripheral nerve stimulation with inter-lead stimulation for axial neck and low back pain: case series and review of the literature
    Abram H Burgher
    The Pain Center of Arizona, Peoria, Arizona 85381, USA
    Neuromodulation 15:100-6; discussion 106-7. 2012
    ..Interest in subcutaneous peripheral nerve stimulation (SQ PNS) as an alternative to SCS has emerged, but the most appropriate electrode locations and neurostimulator programming techniques are not yet clear...
  41. ncbi Predicting outcome of TENS in chronic pain: a prospective, randomized, placebo controlled trial
    Jan Oosterhof
    Pain Expertise Centre, Department of Anesthesiology, Radboud University Nijmegen Medical Centre, Geert Grooteplein 10, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Pain 136:11-20. 2008
    ..The origin of pain and cognitive coping strategies were evaluated as possible predictors for result of TENS treatment...
  42. ncbi The effects of electro-acupuncture and transcutaneous electrical nerve stimulation on patients with painful osteoarthritic knees: a randomized controlled trial with follow-up evaluation
    M M L Ng
    Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hong Kong, China
    J Altern Complement Med 9:641-9. 2003
    ..To examine the relative effectiveness of electro-acupuncture (EA) and transcutaneous electrical nerve stimulation (TENS) in alleviating osteoarthritic (OA)-induced knee pain...
  43. ncbi Percutaneous neuromuscular electrical stimulation (P-NMES) for treating shoulder pain in chronic hemiplegia. Effects on shoulder pain and quality of life
    Gerbert J Renzenbrink
    Roessingh Research and Development and Rehabilitation centre Het Roessingh, Enschede, The Netherlands
    Clin Rehabil 18:359-65. 2004
    ..To evaluate the effect of percutaneous neuromuscular electrical stimulation (P-NMES) of the shoulder muscles on shoulder pain intensity and health-related quality of life in chronic hemiplegia...
  44. ncbi The use of electrical devices for the treatment of bladder dysfunction: a review of methods
    Michael R van Balken
    Department of Urology, University Medical Center Nijmegen, NL 6500 HB Nijmegen, The Netherlands
    J Urol 172:846-51. 2004
    ..We reviewed the literature on the application of various devices and techniques for the electrical stimulation treatment of lower urinary tract dysfunction with respect to mechanism of action and clinical outcome...
  45. ncbi Effects of interferential therapy parameter combinations upon experimentally induced pain in pain-free participants: a randomized controlled trial
    Myrto D Dounavi
    Bioengineering Unit, University of Strathclyde, Glasgow, United Kingdom
    Phys Ther 92:911-23. 2012
    ..Little evidence exists regarding parameter selection for hypoalgesia using interferential therapy (IFT)...
  46. pmc Single-lead percutaneous peripheral nerve stimulation for the treatment of hemiplegic shoulder pain: a case report
    Richard D Wilson
    Cleveland Functional Electrical Stimulation Center, Case Western Reserve University, Cleveland, OH, USA
    Arch Phys Med Rehabil 92:837-40. 2011
    ..Additional studies are needed to further demonstrate safety and efficacy, determine optimal dose, define optimal prescriptive parameters, expand clinical indications, and demonstrate long-term effect...
  47. ncbi Effects of carrier frequency of interferential current on pressure pain threshold and sensory comfort in humans
    Roberta Ceila Venancio
    Physical Therapy Department, University of the City of Sao Paulo UNICID, Sao Paulo, Brazil
    Arch Phys Med Rehabil 94:95-102. 2013
    ..To assess the effect of carrier frequency of interferential current (IFC) on pressure pain threshold (PPT) and sensory comfort in healthy subjects...
  48. ncbi Reduction in inflammation-induced sensitization of dorsal horn neurons by transcutaneous electrical nerve stimulation in anesthetized rats
    Y T Ma
    Physical Therapy Graduate Program, Neuroscience Graduate Program, College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Exp Brain Res 137:94-102. 2001
    ..TENS had no effect on responses of LT neurons. In summary, central neuron sensitization is reduced by TENS and may underlie the reduction in hyperalgesia observed after treatment with TENS...
  49. ncbi Effect of conventional TENS on pain and electromyographic activity of masticatory muscles in TMD patients
    Delaine Rodrigues
    Methodist University of Piracicaba
    Braz Oral Res 18:290-5. 2004
    ..It is possible to conclude that a single TENS application is effective in pain reduction. However, it does not act homogeneously on the features of the electric activity of the muscles evaluated...
  50. ncbi Effects of transcutaneous electrical nerve stimulation (TENS) and interferential currents (IFC) in patients with nonspecific chronic low back pain: randomized clinical trial
    Ligia Maria Facci
    Centro Universitario de Maringa, Parana, Brazil
    Sao Paulo Med J 129:206-16. 2011
    ..The aim of this study was to compare the effects of TENS and interferential current among patients with nonspecific chronic low back pain...
  51. ncbi Transcutaneous electric nerve stimulation for the treatment of postthoracotomy pain: a randomized prospective study
    O Solak
    Department of Thoracic Surgery, Afyon Kocatepe University, School of Medicine, Afyonkarahisar, Turkey
    Thorac Cardiovasc Surg 55:182-5. 2007
    ..We aimed to assess the efficacy of transcutaneous electric nerve stimulation (TENS) in patients with postthoracotomy pain.
  52. ncbi Suppression of pelvic pain during hysteroscopy with a transcutaneous electrical nerve stimulation device
    Carlo De Angelis
    Department of Gynecological Science and Perinatology, Policlinico Umberto I, University of Rome La Sapienza, Italy
    Fertil Steril 79:1422-7. 2003
    ..To evaluate the effectiveness of transcutaneous electrical nerve stimulation (TENS) as a pain control method during office hysteroscopy...
  53. ncbi Local transcutaneous electrical stimulation (TENS) effects in experimental inflammatory edema and pain
    Marcos A Resende
    Departamento de Fisioterapia da Escola de Educação Física, Fisioterapia e Terapia Ocupacional da Universidade Federal de Minas Gerais Av Antônio Carlos, 6627, CEP 31270 901, Belo Horizonte, MG, Brazil
    Eur J Pharmacol 504:217-22. 2004
    ..Thus, our data demonstrated absence of an antiinflammatory effect associated to TENS use and confirmed the participation of endogenous opioids on low TENS-induced analgesia...
  54. ncbi [Frequency-specific responses of human brain to peripheral transcutaneous electric nerve stimulation: a functional magnetic resonance imaging study]
    Z Jin
    Magnetic Resonance Imaging Unit, Hospital 306, Beijing 100101
    Sheng Li Xue Bao 53:275-80. 2001
    The purpose of the present investigation was to determine the responses of human brain to transcutaneous electric nerve stimulation (TENS) at different frequencies by functional magnetic resonance imaging (fMRI) examinations covering the ..
  55. pmc Transcutaneous electrical nerve stimulation for the management of tennis elbow: a pragmatic randomized controlled trial: the TATE trial (ISRCTN 87141084)
    Linda S Chesterton
    Arthritis Research Campaign National Primary Care Centre, Keele University, Staffordshire ST5 5BG, UK
    BMC Musculoskelet Disord 10:156. 2009
    ..It also benefits from being patient controlled, thereby promoting self-management. This study aims to assess the effectiveness, in terms of pain relief, and cost-effectiveness of a self-management package of treatment that includes TENS...
  56. ncbi Transcutaneous electrical nerve stimulation (TENS) can reduce postoperative analgesic consumption. A meta-analysis with assessment of optimal treatment parameters for postoperative pain
    Jan Magnus Bjordal
    Section of Physiotherapy Science, University of Bergen, Bergen 5009, Norway
    Eur J Pain 7:181-8. 2003
    ....
  57. ncbi Evidence-informed management of chronic low back pain with transcutaneous electrical nerve stimulation, interferential current, electrical muscle stimulation, ultrasound, and thermotherapy
    Stéphane Poitras
    Department of Epidemiology and Biostatistics, Faculty of Medicine, McGill University, Montreal, Quebec, Canada
    Spine J 8:226-33. 2008
    ..It is hoped that articles in this special focus issue will be informative and aid in decision making for the many stakeholders evaluating nonsurgical interventions for CLBP...
  58. ncbi Investigation of motor unit recruitment during stimulated contractions of tibialis anterior muscle
    L Mesin
    Laboratorio di Ingegneria del Sistema Neuromuscolare e della Riabilitazione Motoria LISiN, Dipartimento di Elettronica, Politecnico di Torino, Turin, Italy
    J Electromyogr Kinesiol 20:580-9. 2010
    ..Marginal effect of MU excitation thresholds was observed, suggesting that MUs closer to the stimulation electrode are recruited first during TES regardless of their excitability...
  59. ncbi Prospective, Randomized, Placebo-controlled Study of the Effect of TENS on postthoracotomy pain and pulmonary function
    Mükerrem Erdogan
    Department of Thoracic Surgery, Akdeniz University Faculty of Medicine, GKDC Anabilim Dali, Antalya, 07058, Turkey
    World J Surg 29:1563-70. 2005
    ..TENS is thus beneficial for pain relief following thoracotomy and has no side effects. Consequently, the routine use of TENS following thoracic surgery is recommended...
  60. ncbi Optimal stimulation frequency of transcutaneous electrical nerve stimulation on people with knee osteoarthritis
    Pearl P W Law
    Physiotherapy Department, Chi Lin Care and Attention Home, Hong Kong
    J Rehabil Med 36:220-5. 2004
    ..This is a double blind study that examined the optimal stimulation frequency of transcutaneous electrical nerve stimulation in reducing pain due to knee osteoarthritis...
  61. ncbi Carpal tunnel syndrome pain treated with low-level laser and microamperes transcutaneous electric nerve stimulation: A controlled study
    Margaret A Naeser
    Department of Neurology, Boston University School of Medicine, Psychology Research Service, MA, USA
    Arch Phys Med Rehabil 83:978-88. 2002
    To investigate whether real or sham low-level laser therapy (LLLT) plus microamperes transcutaneous electric nerve stimulation (TENS) applied to acupuncture points significantly reduces pain in carpal tunnel syndrome (CTS).
  62. ncbi Optimal stimulation duration of tens in the management of osteoarthritic knee pain
    Gladys L Y Cheing
    Department of Rehabilitation Sciences, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong
    J Rehabil Med 35:62-8. 2003
    ..This study examined the optimal stimulation duration of transcutaneous electrical nerve stimulation (TENS) for relieving osteoarthritic knee pain and the duration (as measured by half-life) of post-stimulation analgesia...
  63. ncbi Release of endogenous opioids following transcutaneous electric nerve stimulation in an experimental model of acute inflammatory pain
    George S Sabino
    Rehabilitation Sciences Program, Federal University of Minas Gerais, Minas Gerais, Brazil
    J Pain 9:157-63. 2008
    b>Transcutaneous electric nerve stimulation (TENS) is a noninvasive treatment used in physiotherapy practice to promote analgesia in acute and chronic inflammatory conditions...
  64. ncbi Transcutaneous functional electrical stimulation for grasping in subjects with cervical spinal cord injury
    S Mangold
    Automatic Control Laboratory, Swiss Federal Institute of Technology Zurich ETHZ, Zurich, Switzerland
    Spinal Cord 43:1-13. 2005
    ..Case series...
  65. ncbi Segmental noxious versus innocuous electrical stimulation for chronic pain relief and the effect of fading sensation during treatment
    Ruth Defrin
    Department of Physical Therapy, School of Allied Health Professions, Sackler Faculty of Medicine, Tel Aviv University, 69978 Ramat Aviv, Israel
    Pain 115:152-60. 2005
    ..Possible mechanisms explaining the findings are discussed...
  66. pmc Transcutaneous electrical nerve stimulation at both high and low frequencies activates ventrolateral periaqueductal grey to decrease mechanical hyperalgesia in arthritic rats
    J M DeSantana
    Department of Physical Therapy, Federal University of Sergipe, Cidade Universitária Professor José Aloísio de Campos Av Marechal Rondon s n, Jardim Rosa Else, São Cristóvão Sergipe, Brazil
    Neuroscience 163:1233-41. 2009
    b>Transcutaneous electric nerve stimulation (TENS) is widely used for the treatment of pain. TENS produces an opioid-mediated antinociception that utilizes the rostroventromedial medulla (RVM)...
  67. pmc Modulation between high- and low-frequency transcutaneous electric nerve stimulation delays the development of analgesic tolerance in arthritic rats
    Josimari M Desantana
    Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, IA 52242, USA
    Arch Phys Med Rehabil 89:754-60. 2008
    To investigate whether repeated administration of modulating frequency transcutaneous electric nerve stimulation (TENS) prevents development of analgesic tolerance.
  68. pmc The effect of electrical neurostimulation on collateral perfusion during acute coronary occlusion
    Jessica de Vries
    Dept of Cardiology, Thoraxcenter, University Medical Centre Groningen, University of Groningen, Groningen, The Netherlands
    BMC Cardiovasc Disord 7:18. 2007
    ..We sought to study the effect of electrical neurostimulation on collateral perfusion...
  69. ncbi Results of sacral neuromodulation therapy for urinary voiding dysfunction: outcomes of a prospective, worldwide clinical study
    Philip E V van Kerrebroeck
    Academisch Ziekenhuis Maastricht, Maastricht, The Netherlands
    J Urol 178:2029-34. 2007
    ..This 5-year, prospective, multicenter trial evaluated the long-term safety and efficacy of sacral neuromodulation in patients with refractory urge incontinence, urgency frequency and retention...
  70. pmc Short-term efficacy of physical interventions in osteoarthritic knee pain. A systematic review and meta-analysis of randomised placebo-controlled trials
    Jan M Bjordal
    Faculty of Health and Social Sciences, Institute of Physiotherapy, Bergen University College, Moellendalsvn, Bergen Norway
    BMC Musculoskelet Disord 8:51. 2007
    ..Treatment efficacy of physical agents in osteoarthritis of the knee (OAK) pain has been largely unknown, and this systematic review was aimed at assessing their short-term efficacies for pain relief...
  71. ncbi Sacral neuromodulation for the treatment of refractory interstitial cystitis: outcomes based on technique
    Kenneth M Peters
    Department of Urology, William Beaumont Hospital, 3535 West 13 Mile Rd, Suite 438, Royal Oak, MI 48073, USA
    Int Urogynecol J Pelvic Floor Dysfunct 14:223-8; discussion 228. 2003
    ..We concluded that sacral nerve modulation can treat refractory IC symptoms. The response to therapy and the reoperation rate are dependent on the technique used to test and implant the device...
  72. ncbi Sensory stimulation (TENS): effects of parameter manipulation on mechanical pain thresholds in healthy human subjects
    Linda S Chesterton
    Department of Physiotherapy Studies, Keele University, Staffordshire ST5 5BG, UK
    Pain 99:253-62. 2002
    ..Stimulation at a combination of the two sites did not produce any greater hypoalgesic effects. These results may have implications for the clinical use of sensory stimulation...
  73. ncbi Efficacy of electrical nerve stimulation for chronic musculoskeletal pain: a meta-analysis of randomized controlled trials
    Michael Johnson
    Philosopher s River Consultancy, Willow Creek, MT 59760, USA
    Pain 130:157-65. 2007
    ..0005). These results indicate that ENS is an effective treatment modality for chronic musculoskeletal pain and that previous, equivocal results may have been due to underpowered studies...
  74. ncbi Different profiles of buprenorphine-induced analgesia and antihyperalgesia in a human pain model
    Wolfgang Koppert
    Department of Anaesthesiology, University Hospital Erlangen, Krankenhausstrasse 12, D 91054 Erlangen, Germany
    Pain 118:15-22. 2005
    ..It will be of major clinical interest whether this difference will translate into improved treatment of pain states dominated by central sensitization...
  75. ncbi Transcutaneous electric nerve stimulation: the effect of intensity on local and distal cutaneous blood flow and skin temperature in healthy subjects
    Fiona L Cramp
    Rehabilitation Sciences Research Group, School of Rehabilitation Sciences, University of Ulster at Jordanstown, County Antrim, Northern Ireland, UK
    Arch Phys Med Rehabil 83:5-9. 2002
    To determine what effect transcutaneous electric nerve stimulation (TENS) intensity has on local and distal cutaneous blood flow and skin temperature.
  76. ncbi Chronic idiopathic pain syndromes
    Debajit Sen
    Department of Rheumatology, University College of London Hospitals NHS Trust and Great Ormond Street Hospital NHS Trust, Arthur Stanley House, 40 50 Tottenham Street, London W1T 4NJ, UK
    Best Pract Res Clin Rheumatol 20:369-86. 2006
    ..Practical problems and issues are dealt with throughout the review in order to construct a pragmatic approach that the authors intend to be of everyday use to the clinician and allied health professionals...
  77. ncbi Involvement of peripheral opioid mechanisms in electroacupuncture analgesia
    Grant G Zhang
    Complementary Medicine Program, University of Maryland School of Medicine, Baltimore, USA
    Explore (NY) 1:365-71. 2005
    ..These data strongly suggest that peripheral opioids are released by EA at the inflammatory site...
  78. ncbi TENS of unknown value in the treatment of chronic low back pain
    Julia Hush
    University of Sydney
    Aust J Physiother 52:64. 2006
  79. ncbi A geriatrician's guide to the use of the physical modalities in the treatment of pain and dysfunction
    Danielle Marie Perret
    Department of Rehabilitation Medicine, The Mount Sinai Medical Center, 1425 Madison Avenue, Box 1240, New York, NY 10029 6574, and Department of Anesthesiology, The State University of New York Health Sciences Center at Brooklyn, NY 11203 2098, USA
    Clin Geriatr Med 22:331-54; ix. 2006
    ..It also highlights the role of the physical modalities as agents for the management of pain in the geriatric population...
  80. ncbi The sustained benefits of long-term neurostimulation in patients with refractory chest pain and normal coronary arteries
    Jessica de Vries
    Department of Cardiology, Thoraxcenter, University Medical Center Groningen, University of Groningen, PO Box 30 001, 9700 RB Groningen, The Netherlands
    Eur J Pain 11:360-5. 2007
    ..To assess the long-term efficacy of neurostimulation for treating refractory angina pectoris-like chest pain, we followed patients, treated with either transcutaneous electrical nerve stimulation (TENS) or spinal cord stimulation (SCS)...
  81. ncbi Efficacy and safety of acupuncture for chronic uncomplicated neck pain: a randomised controlled study
    Jorge Vas
    Pain Treatment Unit, Dos Hermanas A Primary Healthcare Centre, Dos Hermanas, Sevilla, Spain
    Pain 126:245-55. 2006
    ..In the treatment of the intensity of chronic neck pain, acupuncture is more effective than the placebo treatment and presents a safety profile making it suitable for routine use in clinical practice...
  82. ncbi Physical agents used in the management of chronic pain by physical therapists
    Roger J Allen
    Department of Physical Therapy, University of Puget Sound, 1500 North Warner, CMB 1070, Tacoma, WA 98416, USA
    Phys Med Rehabil Clin N Am 17:315-45. 2006
    ..Until controlled efficacy findings are definitive, careful individual patient response monitoring of thoughtful theoretical application of adjunctive physical agents may be a prudent approach to the management of chronic pain...
  83. ncbi Comparison of stochastic vs. conventional transcutaneous electrical stimulation for pain modulation in patients with electromyographically documented radiculopathy
    Donna M Bloodworth
    Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, 3601 North MacGregor Way, Room 240B, Houston, TX 77004, USA
    Am J Phys Med Rehabil 83:584-91. 2004
    ..To determine if a transcutaneous electrical stimulation (TENS) unit modified to deliver electrical impulses at random (R) or stochastic frequency, called TENS-R, provided better pain relief than conventional TENS...
  84. ncbi [Use of stimulation techniques in pain treatment]
    Palle Rosted
    Sheffield Universitet, Sheffield, England
    Ugeskr Laeger 168:1982-6. 2006
    ..The effect of acupuncture and epidural stimulation technique is scientifically well-supported. For the remaining techniques, the scientific evidence is dubious...
  85. ncbi Assessment of efficacy of transcutaneous electrical nerve stimulation for pain management during office-based flexible cystoscopy
    Gregory Hruby
    Department of Urology, Columbia University School of Medicine, New York, New York 10032, USA
    Urology 67:914-7. 2006
    ..To evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for its effectiveness in eliminating or minimizing discomfort during office-based flexible cystoscopy...
  86. ncbi Understanding pain, part 2: pain management
    Helen Godfrey
    Faculty of Health and Social Care, University of the West of England, Bristol, UK
    Br J Nurs 14:904-9. 2005
    ..The three main types of pharmaceutical agents used, non-opioids, opioids and adjuvant drugs, are introduced and their mechanisms of actions discussed...
  87. pmc Outcome of transcutaneous electrical nerve stimulation in chronic pain: short-term results of a double-blind, randomised, placebo-controlled trial
    Jan Oosterhof
    Research Centre for Allied Health Care, 645 Department of Physiotherapy CSS, Radboud University Nijmegen Medical Centre, 6500 HB, Nijmegen, The Netherlands
    J Headache Pain 7:196-205. 2006
    ..Only for patients satisfied with treatment results pain intensity gradually decrease equally both for TENS and sham TENS with repeated treatment application...
  88. ncbi Transcutaneous electrical nerve stimulation for the treatment of chronic low back pain: a systematic review
    Amole Khadilkar
    School of Rehabilitation Sciences, University of Ottawa, Ottawa, Ontario, Canada
    Spine (Phila Pa 1976) 30:2657-66. 2005
    ..Systematic review...
  89. ncbi Pain assessment and management for a dialysis patient with diabetic peripheral neuropathy
    Jennifer Innis
    Pain Service, St Michael s Hospital, Toronto, Ontario
    CANNT J 16:12-7, 20-6; quiz 18-9, 27-8. 2006
    ..Complementary therapies have also been used in pain management in patients with ESRD, and there is a need for greater research in this area...
  90. ncbi Pain: geriatric self-learning module
    Cindy Westley
    University of Virginia Health System, Charlottesville, VA, USA
    Medsurg Nurs 13:399-404. 2004
    ..The Pain: Geriatric Self-Learning Module to published here, along with a post-test. This is the second in a four-part publication of self-learning modules...
  91. ncbi Fundamentals of pain management in wound care
    Sarah Coulling
    Acute Pain Service, Epsom and St Helier University Hospitals NHS Trust
    Br J Nurs 16:S4-6, S8, S10 passim. 2007
    ..Procedural pain with dressing removal and cleansing caused the greatest concerns. An overview of simple, evidence-based drug and non-drug techniques is offered as potential strategies to help minimize the experience of pain...
  92. ncbi Analgesic and disease modifying effects of interferential current in psoriatic arthritis
    U A Walker
    Department of Rheumatology and Clinical Immunology, Albert Ludwigs University, Medizinische Universitatsklinik, Hugstetterstr 55, 79106 Freiburg, Germany
    Rheumatol Int 26:904-7. 2006
    ..Bone scintigraphy showed a trend towards deterioration. New joints became inflamed within treated sites. Thus IFC has analgesic effects in PsA, but does not have a satisfactory disease modifying effect...
  93. ncbi Spinal cord stimulation
    A Costantini
    Unit of Physiopathology and Therapy of Pain, SS Annunziata Hospital, and Department of Anesthesia and Resuscitation, G D Annunzio University, Chieti, Italy
    Minerva Anestesiol 71:471-4. 2005
    ..In this situation SCS seems to improve notably pain control and quality of life index of patients...
  94. ncbi Decreasing pain in electrical nerve stimulation
    Kristof Verhoeven
    Department of Neurology and Clinical Neurophysiology, Leiden University Medical Centre, Room K5Q 108, P O Box 9600, 2300 RC Leiden, The Netherlands
    Clin Neurophysiol 117:972-8. 2006
    ..Do large stimulation electrodes reduce pain in nerve conduction testing?..
  95. ncbi Anti-hyperalgesia properties of buprenorphine
    Marc A Russo
    Pain 122:216; author reply 216. 2006
  96. ncbi Transcutaneous electrical nerve stimulation reduces acute low back pain during emergency transport
    Alexander Bertalanffy
    Department of Neurosurgery, University of Vienna, Vienna, Austria
    Acad Emerg Med 12:607-11. 2005
    ..Patients with acute low back pain may require emergency transport because of pain and immobilization. Transcutaneous electrical nerve stimulation (TENS) is a nonpharmaceutical therapy for patients with low back pain...
  97. ncbi Comparison of the effects of tens and sodium salicylate iontophoresis in the management of osteoarthritis of the knee
    C B Aiyejusunle
    Department of Physiotheropy, School of Clinical Sciences, College of Medicine, University of Lagos Lagos, Nigeria
    Nig Q J Hosp Med 17:30-4. 2007
    ..05). It is hereby suggested that the use of sodium salicylate iontophoresis and TENS be included in treatment of osteoarthritis to enhance pain relief and functional activity...
  98. ncbi Natural history of chronic pain and pain treatment in adults with cerebral palsy
    Mark P Jensen
    Department of Rehabilitation Medicine, School of Medicine, University of Washington, Seattle, Washington 98105 6490, USA
    Am J Phys Med Rehabil 83:439-45. 2004
    ..To determine if cerebral palsy-related pain and frequency of use of pain treatments change over time and to examine the association between use of pain treatments and changes in pain intensity...
  99. ncbi Hypoalgesic effect of the transcutaneous electrical nerve stimulation following inguinal herniorrhaphy: a randomized, controlled trial
    Josimari M Desantana
    Graduate Program in Physical Therapy and Rehabilitation Science, University of Iowa, Iowa City, Iowa 52242, USA
    J Pain 9:623-9. 2008
    ..Consequently, the routine use of TENS after inguinal herniorrhaphy is recommended...
  100. ncbi An investigation into the analgesic effects of interferential currents and transcutaneous electrical nerve stimulation on experimentally induced ischemic pain in otherwise pain-free volunteers
    Mark I Johnson
    School of Health Sciences, Faculty of Health and Environment, Leeds Metropolitan University, Calverly St, Leeds LS1 3HE, United Kingdom
    Phys Ther 83:208-23. 2003
    ..This study compared the analgesic effects of IFC and TENS on experimentally induced ischemic pain in otherwise pain-free subjects using a modified version of the submaximal-effort tourniquet technique...
  101. ncbi Managing musculoskeletal complaints with rehabilitation therapy: summary of the Philadelphia Panel evidence-based clinical practice guidelines on musculoskeletal rehabilitation interventions
    Geoffrey R Harris
    Kaiser Foundation Research Institute, Oakland, California, USA
    J Fam Pract 51:1042-6. 2002
    ..The Philadelphia Panel recently formulated evidence-based guidelines for selected rehabilitation interventions in the management of low back, knee, neck, and shoulder pain...

Research Grants51

  1. Community Ambulation Following Hip Fracture
    Jay Magaziner; Fiscal Year: 2013
    ..This study will evaluate a 16-week multi-component exercise program provided to patients in their homes to determine if it is effective in improving the ability to walk independently in the community (i.e., community ambulation). ..
  2. Anticonvulsant effects of novel concentric ring electrode electrical stimulation
    WALTER GRANT BESIO; Fiscal Year: 2010
    ..A non-invasive therapeutic strategy for bedside and/or out-of-hospital intervention can significantly improve morbidity and mortality, as well as reduce risk and cost of treatment. ..
  3. Fibromyalgia Activity Study with TENS "FAST"
    Kathleen A Sluka; Fiscal Year: 2013
    ..Aim 4: determine if PROMIS is a useful outcome for fibromyalgia by comparing to the revised version of the fibromyalgia impact questionnaire (FIQ-R). ..
  4. Restoring arm and hand motor function with non-invasive spinal stimulation.
    REGGIE EDGERTON; Fiscal Year: 2013
    ..This Phase I proposal will deliver a device that can painlessly and non-invasively aid in the recovery of SCI by delivering a specific electrical stimulation paradigm to the cervical cord that improves use of the arms and hands. ..
  5. A Theranostic Tool to Assess and Enable Spared Spinal Motor Function After SCI
    Daniel Lu; Fiscal Year: 2013
    ..abstract_text> ..
  6. Active Distributed Electrode Array Network for Electrical Stimulation Therapy
    Eric C Hartman; Fiscal Year: 2012
    ..The target markets for this device will be specialized clinics, research groups, and OEM companies. The target price for the system will be $3000 in volume for an 8-channel configuration (OEM market). ..
  7. HEALING DECUBITUS ULCERS WITH TENS
    Rita Frantz; Fiscal Year: 1991
    ..Within treatment groups, patient and ulcer condition variables will be correlated with differences in measures of rate of healing...
  8. Intramuscular Electrical Stimulation for Low Back Pain
    Zi Ping Fang; Fiscal Year: 2003
    ..abstract_text> ..
  9. BEHAVIORAL AND BIOCHEMICAL MECHANISMS OF SELF INJURY
    Frank Symons; Fiscal Year: 2001
    ..Accordingly, treatments will include transcutaneous electric nerve stimulation (TENS)(an opioid agonist treatment) or naltrexone (an opioid antagonist treatment)...
  10. Active Distributed Electrode Array Network for Electrical Stimulation Therapy
    Eric Hartman; Fiscal Year: 2009
    ....
  11. APS Travel Award
    Kathleen Sluka; Fiscal Year: 2007
    ..C. These funds will allow trainees to attend and interact with both clinicians and researchers from multiple disciplines including medicine, nursing, psychology, and physical therapy. [unreadable] [unreadable] [unreadable]..
  12. Central contributions to pathobiology of fibromyalgia
    Kathleen Sluka; Fiscal Year: 2009
    ..A better understanding of the pathobiological mechanisms underlying musculoskeletal pain conditions may lead to the development of novel therapeutic approaches for its treatment. ..
  13. Role of ASIC3 in the etiology of fibromyalgia
    Kathleen A Sluka; Fiscal Year: 2010
    ..These studies could lead to peripherally based therapeutic approaches to control pain without undesirable CMS (central nervous system) side effects, including gene therapy. ..
  14. Neurobiology of Joint Manipulation Induced Analgesia
    Kathleen Sluka; Fiscal Year: 2003
    ..This information will further assist the clinician in determining the treatment of choice for a particular patient and potentially guide future clinical research. ..
  15. Transcutaneous electrical stimulation of conductive polymers to promote nerve re-
    SILVIA LUEBBEN; Fiscal Year: 2008
    ..This research is essential to the future development of a transcutaneous stimulation system to promote in vivo nerve growth. [unreadable] [unreadable] [unreadable]..
  16. NEUROBIOLOGY OF CHRONIC MUSCLE PAIN
    Kathleen Sluka; Fiscal Year: 2003
    ..These proposed studies will help in the understanding and thus potential treatment of chronic muscle pain, including such conditions as fibromyalgia, myofascial pain and low back pain. ..
  17. Neurobiology of Musculoskeletal Pain
    Kathleen Sluka; Fiscal Year: 2005
    ..These proposed studies are intended to help in the understanding and thus potential treatment of chronic muscle pain including such conditions as fibromyalgia, myofascial pain and low back pain. ..
  18. Effectiveness of TENS on Hyperalgesia, Pain with Movement, and Function After TKR
    Barbara Rakel; Fiscal Year: 2010
    ..By improving functional status, older adults can retain independence and possibly reduce their health care utilization and costs. ..
  19. Effect of TENS on Knee Osteoarthritis Pain, Hyperalgesia, and Function
    Barbara Rakel; Fiscal Year: 2008
    ..This will improve the functional status and independence of older adults suffering from this chronic, painful, limiting condition. [unreadable] [unreadable] [unreadable]..
  20. Locomotion Control by Lumbar Spinal Cord Stimulation
    Changfeng Tai; Fiscal Year: 2008
    ..The proposed studies will not only improve our understanding of locomotion control in lumbar spinal cord but also benefit SCI patients. ..
  21. Bladder and Sphincter Control after Spinal Cord Injury
    Changfeng Tai; Fiscal Year: 2008
    ..abstract_text> ..
  22. Beaumont Interstitial Cystitis Clinical Research Network
    Kenneth Peters; Fiscal Year: 2007
    ..Adverse events and complications will be monitored. Ancillary studies as agreed upon by the ICCRN will be carried out in conjunction with the clinical trial. ..
  23. Functional Impact of PENS for 65+ Chronic Low Back Pain
    Debra Weiner; Fiscal Year: 2006
    ....
  24. MOOD EFFECTS OF DEEP BRAIN STIMULATION IN PARKINSONS
    Mark George; Fiscal Year: 2002
    ..Thus, we plan to use interleaved fMRI and DBS to directly examine the effects of DBS on hypothesized brain circuits and to correlate this with immediate and longer-term (4 week) behavioral outcomes (mood and cognition). ..
  25. Osteopuncture for OA-Associated Knee Pain & Disability
    Debra Weiner; Fiscal Year: 2005
    ..In addition, mechanisms of action will be explored, and the impact of osteopuncture on health care costs determined. ..
  26. Optimization of TMS for Depression
    Mark George; Fiscal Year: 2009
    ..This clinical site grant (CSG) proposal is one of four scientifically identical proposals resubmitted under a CSMD mechanism.] ..
  27. Optimization of TMS for Depression - Coordinating Center
    Mark George; Fiscal Year: 2009
    ..This coordinating Center Grant (CCG) application is submitted under a CSMD mechanism, linked to 4 clinical site grants (CSG). ..
  28. Transcranial Magnetic Stimulation to Improve Speech
    Margaret A Naeser; Fiscal Year: 2010
    ..The number of people with aphasia in the U.S. today is estimated to be 1 million;80,000 new cases each year. This research has direct clinical relevance for aphasia patients. ..
  29. Cannabinoid Modulation of Capsaicin-Sensitive Nociceptors
    Kenneth M Hargreaves; Fiscal Year: 2010
    ..Second, identification of cannabinoid modulation of pain via TRPchannels provides a rationale for a novel class of analgesics that are devoid of classical cannabinoid side effects. ..
  30. Impaired Wound Healing in Diabetic Foot Ulceration
    Aristidis Veves; Fiscal Year: 2010
    ..In addition we believe that it will be helpful in understanding the relationship between cardiovascular disease and wound healing. ..
  31. Primary and Secondary Nociceptors in Persistent Pain
    H Richard Koerber; Fiscal Year: 2010
    ..By comparing the three groups, we hope to elucidate the specific populations of primary afferent and secondary nociceptive neurons crucial to this process. ..
  32. BIOLOGY OF HUMAN INTRAEPITHELIAL LYMPHOCYTES
    Ellen Ebert; Fiscal Year: 2002
    ..These studies will determine the mechanism of IEL chemotaxis toward secreted products of ECs, why IL-15 is more potent than IL-2 in inducing LAK activity by IELs, and how IL-10 and IL-12 augment this activity. ..
  33. Consistency of TCM RA Diagnosis and Herbal Prescriptions
    Grant Zhang; Fiscal Year: 2002
    ..More importantly, this study will be broadly applicable to clinical TCM research in general, and may help to establish a stronger methodological model for the evaluation of individualized treatment. ..
  34. PERIPHERAL CANNABINOIDS AND NEUROGENIC INFLAMMATION
    Kenneth Hargreaves; Fiscal Year: 2002
    ..This knowledge base may provide a rationale for developing peripherally-selective cannabinoid analgesics with minimal CNS-mediated side-effect liability. ..
  35. SYMPATHETIC FIBER MODULATION OF NEUROGENIC INFLAMMATION
    Kenneth Hargreaves; Fiscal Year: 2003
    ....
  36. ELECTROSTIMULATION FOR HEMIPLEGIA
    John Chae; Fiscal Year: 2004
    ..EMG-controlled NIMES may also be effective for lower extremity motor and functional recovery. ..
  37. Mechanisms of Nicotine Induced Neurogenic Inflammation
    Kenneth Hargreaves; Fiscal Year: 2005
    ....
  38. Relationship of Hematocrit to Ischemic Stroke Outcome
    Paul Diamond; Fiscal Year: 2006
    ..Fitting these models will result in a more complete understanding of the association between HCT and stroke outcome. Findings could lead to the development of new interventions to improve stroke outcome. [unreadable] [unreadable]..
  39. Injury Induced Facilitated Neurogenic Inflammation
    Wade Kingery; Fiscal Year: 2006
    ..abstract_text> ..
  40. Neuropeptide Y Regulation of Peripheral Human Nociceptors and Pain
    Kenneth Hargreaves; Fiscal Year: 2007
    ..Moreover, our study population in South Texas permits secondary analyses of a potentially underserved population (predominantly Hispanic) that is at risk for caries-induced pulpal necrosis and pain. [unreadable] [unreadable]..
  41. NEURAL REGULATION OF BONE REMODELING
    Wade Kingery; Fiscal Year: 2008
    ..These investigations will help to identify the sensory transmitters that modulate bone remodeling and characterize their roles in osteoporotic processes. ..
  42. Electrical stimulation for upper limb recovery in stroke
    John Chae; Fiscal Year: 2008
    ..2. Assess the effect of NMES on upper limb activity limitation. 3. Assess the effect of NMES on central motor processing. 4. Assess the effect of adding cognitive input during NMES therapy. ..
  43. Contralaterally Controlled Functional Electrical Stimulation for Hemiparetic Hand
    Jayme Knutson; Fiscal Year: 2008
    ..As more effective stroke therapies are developed, the prevalence of post-stroke disability may be decreased. [unreadable] [unreadable]..
  44. Acupuncture For Infertility Patients: The Effect On IVF
    Grant Zhang; Fiscal Year: 2007
    ..Result obtained from the study will provide necessary information for a larger, definitive study, as well as knowledge regarding the broad mechanism of acupuncture on female reproductive function. [unreadable] [unreadable]..
  45. Subacute Stroke Recovery: Bimanual Coordination Training
    James Cauraugh; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  46. Electrical Stimulation for Hemiplegic Shoulder Pain
    John Chae; Fiscal Year: 2010
    ..We further postulate that ES improves glenohumeral stability by facilitating motor recovery. Thus we will evaluate the effects of these treatments on objective measures of poststroke motor recovery. ..
  47. ELECTROSTIMULATION FOR STROKE REHAB: EFFECTS & MECHANISM
    John Chae; Fiscal Year: 2002
    ..Finally, techniques developed for assessing central motor function may be useful for evaluating other interventions directed at stroke rehabilitation. ..
  48. FES for foot-drop in hemiparesis
    John Chae; Fiscal Year: 2009
    ..This proposed approach is expected to improve patient outcome and challenge the present clinical paradigm of prescribing AFOs for stroke survivors with foot-drop. ..
  49. Vascular and Metabolic Changes in the Diabetic Foot
    Aristidis Veves; Fiscal Year: 2005
    ..Therefore, the combination of MRI RARE measurements and HIS will effectively identify patients at risk of foot ulceration and also predict failure to heal an ulcer. ..
  50. Natural History of Peripheral Diabetic Neuropathy
    Aristidis Veves; Fiscal Year: 2009
    ..What are the required numbers of patients and the required length of time so a clinical trial is properly powered? ..