computer assisted drug therapy

Summary

Summary: Adjunctive computer programs in providing drug treatment to patients.

Top Publications

  1. ncbi Computerized physician order entry and medication errors in a pediatric critical care unit
    Amy L Potts
    Department of Pharmaceutical Services, Vanderbilt Children s Hospital, Nashville, Tennessee 37212 1565, USA
    Pediatrics 113:59-63. 2004
  2. ncbi Effects of computerized physician order entry and clinical decision support systems on medication safety: a systematic review
    Rainu Kaushal
    Division of General Internal Medicine, Brigham and Women s Hospital, Partners HealthCare System, Boston, Mass, USA
    Arch Intern Med 163:1409-16. 2003
  3. pmc Improving ambulatory prescribing safety with a handheld decision support system: a randomized controlled trial
    Eta S Berner
    Department of Health Services Administration, University of Alabama at Birmingham, 1675 University Boulevard, Room 544, Birmingham, AL 35294 3361, USA
    J Am Med Inform Assoc 13:171-9. 2006
  4. pmc Computerized physician order entry: helpful or harmful?
    Robert G Berger
    University of North Carolina School of Medicine, UNC Health Care System, CB 7280, Chapel Hill, NC 27599, USA
    J Am Med Inform Assoc 11:100-3. 2004
  5. pmc Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit
    Rob Shulman
    Pharmacy Department, University College London Hospitals, Middlesex Hospital, London, UK
    Crit Care 9:R516-21. 2005
  6. pmc The medical office of the 21st century (MOXXI): effectiveness of computerized decision-making support in reducing inappropriate prescribing in primary care
    Robyn Tamblyn
    Department of Medicine, McGill University, Montreal, Que
    CMAJ 169:549-56. 2003
  7. ncbi Use of computerized decision support systems to improve antibiotic prescribing
    Karin Thursky
    Infectious Diseases Physician, Centre for Clinical Research Excellence in Infectious Diseases, Victorian Infectious Diseases Service, Royal Melbourne Hospital, Grattan Street, Parkville, Victoria, 3051, Australia
    Expert Rev Anti Infect Ther 4:491-507. 2006
  8. pmc The impact of computerized physician order entry on medication error prevention
    D W Bates
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Med Inform Assoc 6:313-21. 1999
  9. ncbi Effects of computerized physician order entry on prescribing practices
    J M Teich
    Department of Emergency Medicine, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115
    Arch Intern Med 160:2741-7. 2000
  10. ncbi A randomized controlled trial comparing a computer-assisted insulin infusion protocol with a strict and a conventional protocol for glucose control in critically ill patients
    Alexandre B Cavalcanti
    Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo 05652 000, Brazil
    J Crit Care 24:371-8. 2009

Detail Information

Publications171 found, 100 shown here

  1. ncbi Computerized physician order entry and medication errors in a pediatric critical care unit
    Amy L Potts
    Department of Pharmaceutical Services, Vanderbilt Children s Hospital, Nashville, Tennessee 37212 1565, USA
    Pediatrics 113:59-63. 2004
    ..The objective of this study was to evaluate the impact of CPOE on the frequency of errors in the medication ordering process in a pediatric critical care unit (PCCU)...
  2. ncbi Effects of computerized physician order entry and clinical decision support systems on medication safety: a systematic review
    Rainu Kaushal
    Division of General Internal Medicine, Brigham and Women s Hospital, Partners HealthCare System, Boston, Mass, USA
    Arch Intern Med 163:1409-16. 2003
    ..Iatrogenic injuries related to medications are common, costly, and clinically significant. Computerized physician order entry (CPOE) and clinical decision support systems (CDSSs) may reduce medication error rates...
  3. pmc Improving ambulatory prescribing safety with a handheld decision support system: a randomized controlled trial
    Eta S Berner
    Department of Health Services Administration, University of Alabama at Birmingham, 1675 University Boulevard, Room 544, Birmingham, AL 35294 3361, USA
    J Am Med Inform Assoc 13:171-9. 2006
    ..To evaluate the effectiveness of a personal digital assistant (PDA)-based clinical decision support system (CDSS) on nonsteroidal anti-inflammatory drug (NSAID) prescribing safety in the outpatient setting...
  4. pmc Computerized physician order entry: helpful or harmful?
    Robert G Berger
    University of North Carolina School of Medicine, UNC Health Care System, CB 7280, Chapel Hill, NC 27599, USA
    J Am Med Inform Assoc 11:100-3. 2004
    ..Installation of such systems could actually increase the number of adverse drug events and result in higher overall medical costs, particularly in the first few years of their adoption...
  5. pmc Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unit
    Rob Shulman
    Pharmacy Department, University College London Hospitals, Middlesex Hospital, London, UK
    Crit Care 9:R516-21. 2005
    ..The study aimed to compare the impact of computerised physician order entry (CPOE) without decision support with hand-written prescribing (HWP) on the frequency, type and outcome of medication errors (MEs) in the intensive care unit...
  6. pmc The medical office of the 21st century (MOXXI): effectiveness of computerized decision-making support in reducing inappropriate prescribing in primary care
    Robyn Tamblyn
    Department of Medicine, McGill University, Montreal, Que
    CMAJ 169:549-56. 2003
    ....
  7. ncbi Use of computerized decision support systems to improve antibiotic prescribing
    Karin Thursky
    Infectious Diseases Physician, Centre for Clinical Research Excellence in Infectious Diseases, Victorian Infectious Diseases Service, Royal Melbourne Hospital, Grattan Street, Parkville, Victoria, 3051, Australia
    Expert Rev Anti Infect Ther 4:491-507. 2006
    ..This review describes computerized decision support systems used to assist with antibiotic prescribing, the evidence for their effectiveness and the current and future roles...
  8. pmc The impact of computerized physician order entry on medication error prevention
    D W Bates
    Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Am Med Inform Assoc 6:313-21. 1999
    ..A small proportion do have the potential to cause injury, and some cause preventable adverse drug events...
  9. ncbi Effects of computerized physician order entry on prescribing practices
    J M Teich
    Department of Emergency Medicine, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115
    Arch Intern Med 160:2741-7. 2000
    ..This study assesses the impact of an inpatient computerized physician order entry system on prescribing practices...
  10. ncbi A randomized controlled trial comparing a computer-assisted insulin infusion protocol with a strict and a conventional protocol for glucose control in critically ill patients
    Alexandre B Cavalcanti
    Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo 05652 000, Brazil
    J Crit Care 24:371-8. 2009
    ..The objective of this study is to evaluate blood glucose (BG) control efficacy and safety of 3 insulin protocols in medical intensive care unit (MICU) patients...
  11. pmc Prescribers' responses to alerts during medication ordering in the long term care setting
    James Judge
    Meyers Primary Care Institute, 630 Plantation Street, Worcester, MA 01605, USA
    J Am Med Inform Assoc 13:385-90. 2006
    ....
  12. ncbi Dosage individualization of erythropoietin using a profile-dependent support vector regression
    José David Martín-Guerrero
    Digital Signal Processing Group, C Dr Moliner, 50 Dpt Eng Elec, Fac Física, Universitat de Valencia, Burjassot 46100, Spain
    IEEE Trans Biomed Eng 50:1136-42. 2003
    ..We perform sensitivity analysis on the MLP and inspect the distribution of the support vectors in the input and feature spaces in order to gain knowledge about the problem...
  13. pmc Randomized trial to improve prescribing safety during pregnancy
    Marsha A Raebel
    Kaiser Permanente Colorado Clinical Research Unit, PO Box 378066, Denver, CO 80237 8066, USA
    J Am Med Inform Assoc 14:440-50. 2007
    ..S. Food and Drug Administration pregnancy risk category D or X medications was effective in decreasing dispensings of these medications...
  14. ncbi A controlled trial of smart infusion pumps to improve medication safety in critically ill patients
    Jeffrey M Rothschild
    Division of General Medicine and Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
    Crit Care Med 33:533-40. 2005
    ..We sought to assess the impact of smart pumps with integrated decision support software on the incidence and nature of medication errors and adverse drug events...
  15. ncbi Clinical decision support systems and antibiotic use
    Nada Atef Shebl
    Department of Practice and Policy, The School of Pharmacy, University of London, BMA House, Mezzanine Floor, Tavistock Square, London WC1H 9JP, UK
    Pharm World Sci 29:342-9. 2007
    ..To review and appraise randomised controlled trials (RCT) and 'before and after' studies published on clinical decision support systems (CDSS) used to support the use of antibiotics...
  16. ncbi Morbidity reduction in critically ill trauma patients through use of a computerized insulin infusion protocol: a preliminary study
    Eric A Toschlog
    Department of Surgery, The Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834, USA
    J Trauma 62:1370-5; discussion 1375-6. 2007
    ..The purpose of our study was to evaluate the effect of a computerized hospital insulin protocol (CHIP) on glycemic control and outcome in critically ill trauma patients...
  17. ncbi Modeling and simulation of cancer immunoprevention vaccine
    F Pappalardo
    Faculty of Pharmacy, University of Catania, Italy
    Bioinformatics 21:2891-7. 2005
    ..We present an in silico model that simulates the immune system responses to tumor cells in naive and vaccinated mice. We have demonstrated the ability of this model to accurately reproduce the experimental results...
  18. ncbi Improving empirical antibiotic treatment using TREAT, a computerized decision support system: cluster randomized trial
    Mical Paul
    Department of Medicine E, Rabin Medical Center, Beilinson Campus, 49100 Petah Tiqva, Israel
    J Antimicrob Chemother 58:1238-45. 2006
    ..Appropriate antibiotic treatment decreases mortality, while superfluous treatment is associated with antibiotic resistance. We built a computerized decision support system for antibiotic treatment (TREAT) targeting these outcomes...
  19. ncbi Tight glycaemic control by an automated algorithm with time-variant sampling in medical ICU patients
    Christoph Pachler
    Department of Internal Medicine, Medical University Graz, Stiftingtalstrasse 24, 8010, Graz, Austria
    Intensive Care Med 34:1224-30. 2008
    ....
  20. ncbi Failure of computerized treatment suggestions to improve health outcomes of outpatients with uncomplicated hypertension: results of a randomized controlled trial
    Michael D Murray
    Department of Medicine, Indiana University School of Medicine, USA
    Pharmacotherapy 24:324-37. 2004
    ..To assess the effects of evidence-based treatment suggestions for hypertension made to physicians and pharmacists using a comprehensive electronic medical record system...
  21. pmc Can computer-generated evidence-based care suggestions enhance evidence-based management of asthma and chronic obstructive pulmonary disease? A randomized, controlled trial
    William M Tierney
    Department of Medicine, Indiana University School of Medicine, M200 OPW, Wishard Memorial Hospital, 1001 West 10th St, Indianapolis, IN 46202, USA
    Health Serv Res 40:477-97. 2005
    ..Translation of evidence-based guidelines into clinical practice has been inconsistent. We performed a randomized, controlled trial of guideline-based care suggestions delivered to physicians when writing orders on computer workstations...
  22. pmc Computer-based insulin infusion protocol improves glycemia control over manual protocol
    Jeffrey B Boord
    Vanderbilt University, Division of Cardiovascular Medicine, Nashville, TN 37232 8802, USA
    J Am Med Inform Assoc 14:278-87. 2007
    ....
  23. pmc Clinical decision support in electronic prescribing: recommendations and an action plan: report of the joint clinical decision support workgroup
    Jonathan M Teich
    Department of Emergency Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    J Am Med Inform Assoc 12:365-76. 2005
    ....
  24. ncbi Impact of computerized physician order entry on clinical practice in a newborn intensive care unit
    Leandro Cordero
    Pediatrics and Obstetrics, The Ohio State University Medical Center, Columbus, OH 43210, USA
    J Perinatol 24:88-93. 2004
    ..To study the impact of computerized physician order entry (CPOE) on selected neonatal intensive care unit (NICU) practices...
  25. ncbi A replicable method for blood glucose control in critically Ill patients
    Alan H Morris
    Pulmonary Division, Department of Medicine, LDS Hospital and the University of Utah School of Medicine, Salt Lake City, UT, USA
    Crit Care Med 36:1787-95. 2008
    ..To ensure interpretability and replicability of clinical experiments, methods must be adequately explicit and should elicit the same decision from different clinicians who comply with the study protocol...
  26. ncbi Implementation of a tight glycaemic control protocol using a web-based insulin dose calculator
    A N Thomas
    Intensive Care Unit, Hope Hospital, Stott Lane, Salford, M6 8HD, UK
    Anaesthesia 60:1093-100. 2005
    ..19-3.73] compared to values < 6.1 mmol.l(-1). However, patient mortality remained constant during the study. Glycaemic control was improved outside a research setting using a protocol supported by a web-based insulin dose calculator...
  27. ncbi Use of a computer-based reminder to improve sedative-hypnotic prescribing in older hospitalized patients
    Joseph V Agostini
    Clinical Epidemiology Research Center, VA Connecticut Healthcare Center, West Haven, CT 06516, USA
    J Am Geriatr Soc 55:43-8. 2007
    ..To develop a feasible, inexpensive, point-of-care computerized reminder to improve sedative-hypnotic prescribing in hospitalized older people...
  28. ncbi Computer decision support systems
    T H Payne
    VA Puget Sound Health Care System, University of Washington, Seattle, WA 98108, USA
    Chest 118:47S-52S. 2000
    ..As computer-based records and order-entry systems become more common, automated decision support systems will be used more broadly...
  29. pmc Design of a safer approach to intravenous drug infusions: failure mode effects analysis
    M Apkon
    333 Cedar Street, New Haven, CT 06520 8064, USA
    Qual Saf Health Care 13:265-71. 2004
    ..Failure modes effects analysis (FMEA) was used to examine the impact of process changes on the reliability of delivering drug infusions...
  30. ncbi Active insulin infusion using optimal and derivative-weighted control
    Z H Lam
    Department of Mechanical Engineering, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
    Med Eng Phys 24:663-72. 2002
    ..Overall, emerging blood glucose sensor technologies that enable frequent measurement are shown to enable more effective, automated control of blood glucose levels within a tight, acceptable range for Type I and II diabetic individuals...
  31. ncbi Comparison of percutaneous acetic acid injection and percutaneous ethanol injection for hepatocellular carcinoma in cirrhotic patients: a prospective study
    T I Huo
    Division of Gastroenterology, Dept of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
    Scand J Gastroenterol 38:770-8. 2003
    ..We conducted a prospective study to compare the therapeutic efficacy of both these methods...
  32. ncbi An intravenous medication safety system: preventing high-risk medication errors at the point of care
    Irene Hatcher
    Case Management, Vanderbilt University Medical Center, 1161 21st Avenue S, Nashville, TN 37232 2415, USA
    J Nurs Adm 34:437-9. 2004
    ....
  33. pmc Improving acceptance of computerized prescribing alerts in ambulatory care
    Nidhi R Shah
    Division of General Medicine, Brigham and Women s Hospital, 1620 Tremont Street, 3rd Floor, Boston, MA 02120, USA
    J Am Med Inform Assoc 13:5-11. 2006
    ..These data suggest that it is possible to design computerized prescribing decision support with high rates of alert recommendation acceptance by clinicians...
  34. pmc A trial of automated decision support alerts for contraindicated medications using computerized physician order entry
    William L Galanter
    University of Illinois at Chicago, Department of Medicine, Section of General Internal Medicine M C 718, 840 S Wood St, Chicago, IL 60612, USA
    J Am Med Inform Assoc 12:269-74. 2005
    ..Because renal insufficiency is a common source of medication errors, the authors studied a trial of alerts designed to reduce inpatient administration of medications contraindicated due to renal insufficiency...
  35. pmc Effect of computerisation on the quality and safety of chemotherapy prescription
    Marc Voeffray
    Pharmacy Service, University Hospital, Lausanne, Switzerland
    Qual Saf Health Care 15:418-21. 2006
    ..Multiple errors can occur during the prescription, the transmission of documents and the drug delivery processes, and lead to potentially serious consequences...
  36. ncbi [Clinical decision support: Is the number of medication errors reduced?]
    Louise Isager Rabøl
    H S Hvidovre Hospital, Dansk Selskab for Patientsikkerhed, København
    Ugeskr Laeger 168:4179-84. 2006
    ..CPOE with CDS is time consuming and may generate new medication errors in itself. All the trials had poor designs. A Danish data source for CDS has not yet been established...
  37. ncbi Ten simple strategies to prevent chemotherapy errors
    Lisa Schulmeister
    Clin J Oncol Nurs 9:201-5. 2005
    ..These strategies can be customized for use in a variety of practice settings. Oncology nurses are at the forefront of chemotherapy error-prevention initiatives and play a key role in implementing safety measures...
  38. ncbi Medication-error reporting and pharmacy resident experience during implementation of computerized prescriber order entry
    Kyle A Weant
    Department of Pharmacy, University of North Carolina Hospitals, 101 Manning Drive, Chapel Hill, NC 27514, USA
    Am J Health Syst Pharm 64:526-30. 2007
    ....
  39. pmc Personal digital assistant-based drug information sources: potential to improve medication safety
    Kimberly A Galt
    Department of Pharmacy Practice, School of Pharmacy and Health Professions, Creighton University, 2500 California Plaza, Omaha, Nebraska 68178, USA
    J Med Libr Assoc 93:229-36. 2005
    ..This study compared the potential for personal digital assistant (PDA)-based drug information sources to minimize potential medication errors dependent on accurate and complete drug information at the point of care...
  40. ncbi Prescribing errors resulting in adverse drug events: how can they be prevented?
    Petra A Thürmann
    Expert Opin Drug Saf 5:489-93. 2006
    ..However, these systems still have some shortcomings and it has not yet convincingly been shown that the use of this technology really improves patient safety...
  41. pmc The development and evaluation of an integrated electronic prescribing and drug management system for primary care
    Robyn Tamblyn
    Department of Epidemiology and Biostatistics, McGill University, Morrice House, 1140 Pine Avenue West, Montreal, Quebec, Canada H3A 1A3
    J Am Med Inform Assoc 13:148-59. 2006
    ..To develop and evaluate the acceptability and use of an integrated electronic prescribing and drug management system (MOXXI) for primary care physicians...
  42. ncbi Automated medication error studies with audit supplementation were effectively designed and analyzed by time series
    Jonathan J Shuster
    Department of Epidemiology and Health Policy Research, College of Medicine, University of Florida, 1600 W Archer Raod, 100212, Gainesville, FL 32610 0212, USA
    J Clin Epidemiol 59:957-63. 2006
    ..To provide researchers with an efficient yet methodologically robust method to design and analyze studies of the effectiveness of quality improvement interventions targeted at medical errors...
  43. ncbi First do no harm: Hamilton Health Sciences' experience as first hospital in the world to fully implement Medley Medication Safety System
    Paul Faguy
    Hamilton Health Sciences
    Healthc Q 8:116-9. 2005
  44. pmc What do we know about medication errors made via a CPOE system versus those made via handwritten orders?
    Ross Koppel
    Center for Clinical Epidemiology and Biostatistics, School of Medicine, and Sociology Department, University of Pennsylvania, Philadelphia, PA, USA
    Crit Care 9:427-8. 2005
    ..I discuss these issues and their implications for the evaluation of CPOE systems and of other emerging healthcare technologies...
  45. ncbi High rates of adverse drug events in a highly computerized hospital
    Jonathan R Nebeker
    Veterans Administration Salt Lake City Health Care System, Geriatric Research, Education, and Clinical Center, Salt Lake City, Utah, USA
    Arch Intern Med 165:1111-6. 2005
    ..We describe the frequency and type of inpatient ADEs that occurred following the adoption of multiple computerized medication ordering and administration systems, including computerized physician order entry (CPOE)...
  46. ncbi Effect of a remote order scanning system on processing medication orders
    Samir Sikri
    Professional Services, MarketRx, Gurgaon, India
    Am J Health Syst Pharm 63:1438-41. 2006
  47. pmc Medication-related clinical decision support in computerized provider order entry systems: a review
    Gilad J Kuperman
    Quality Informatics, NewYork Presbyterian Hospital, 525 E 68 Street, Box 298, New York, NY 10021, USA
    J Am Med Inform Assoc 14:29-40. 2007
    ..The authors conclude with summary recommendations for delivering effective medication-related clinical decision support addressed to healthcare organizations, application and knowledge base vendors, policy makers, and researchers...
  48. ncbi Compelling features of a safe medication-use system
    William N Kelly
    William N Kelly Consulting, Inc, Oldsmar, FL 34677, USA
    Am J Health Syst Pharm 63:1461-8. 2006
  49. pmc Detection and prevention of medication errors using real-time bedside nurse charting
    Nancy C Nelson
    Department of Medical Informatics, LDS Hospital, Salt Lake City, UT 84143, USA
    J Am Med Inform Assoc 12:390-7. 2005
    ..The aim of this study was to increase the real-time bedside charting behavior of nurses...
  50. ncbi Reducing excessive medication administration in hospitalized adults with renal dysfunction
    Ira S Nash
    Zena and Michael A Wiener Cardiovascular Institute and The Marie Josée and Henry R Kravis Center for Cardiovascular Health, Mount Sinai Medical Center, New York, NY 10029, USA
    Am J Med Qual 20:64-9. 2005
    ..1% and 24.8% in the rest of the hospital. Automated detection and routine feedback can reduce the rate of excessive administration of medication in hospitalized adults with renal insufficiency...
  51. ncbi [Frequency, relevance, causes of and strategies for prevention of medication errors]
    D Grandt
    Medizinische Klinik I, Klinikum Saarbrücken, Winterberg 1, 66130, Saarbrucken, Germany
    Z Gerontol Geriatr 38:196-202. 2005
    ..Studies have demonstrated that CPOES can reduce medication errors by 80%. The necessary steps to improve medication safety in Germany are outlined and discussed...
  52. ncbi Computer-supported weight-based drug infusion concentrations in the neonatal intensive care unit
    Gay Giannone
    Siemens Health Systems, Malvern, PA 19355, USA
    Comput Inform Nurs 23:100-5. 2005
    ..In addition, the article provides guidelines on how to customize a vendor solution for hospitals with neonatal intensive care unit...
  53. ncbi Incorporation of a gentamicin dosage calculator into a computerized prescriber-order-entry system
    Agnes L F Chan
    Department of Pharmacy, Chi Mei Medical Center, Tainan, Taiwan
    Am J Health Syst Pharm 63:1344-5. 2006
  54. pmc Clinical decision support and electronic prescribing systems: a time for responsible thought and action
    Randolph A Miller
    Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA
    J Am Med Inform Assoc 12:403-9. 2005
  55. ncbi Medication errors in inpatient pharmacy operations and technologies for improvement
    Seth Alan Kuiper
    University of Michigan Hospitals and Health Centers, Ann Arbor, USA
    Am J Health Syst Pharm 64:955-9. 2007
  56. ncbi Randomized trial to improve prescribing safety in ambulatory elderly patients
    Marsha A Raebel
    Clinical Research Unit, Kaiser Permanente Colorado, Denver, Colorado 80237 8066, USA
    J Am Geriatr Soc 55:977-85. 2007
    ....
  57. pmc A trial of automated safety alerts for inpatient digoxin use with computerized physician order entry
    William L Galanter
    Department of Medicine, Section of General Internal Medicine M C 718, University of Illinois at Chicago, 840 South Wood Street, Chicago, IL 60612, USA
    J Am Med Inform Assoc 11:270-7. 2004
    ....
  58. ncbi Development of a pharmacy-managed medication dictionary in a newly implemented computerized prescriber order-entry system
    Diane Soulliard
    Department of Pharmacy, Beth Israel Deaconess Medical Center, 1 Deaconess Road, Boston, MA 02215, USA
    Am J Health Syst Pharm 61:617-22. 2004
  59. ncbi Preventing provider errors: online total parenteral nutrition calculator
    Christoph U Lehmann
    Division of Neonatology, Department of Pediatrics, Johns Hopkins University, Baltimore, Maryland 21287 3200, USA
    Pediatrics 113:748-53. 2004
    ..To describe the development of a pragmatic low-cost medical information system that reduces errors in the ordering of total parenteral nutrition (TPN) in the newborn intensive care unit at the Johns Hopkins Hospital...
  60. ncbi Interventions to reduce dosing errors in children: a systematic review of the literature
    Sharon Conroy
    Academic Division of Child Health, Derbyshire Children s Hospital, University of Nottingham, Nottingham, UK
    Drug Saf 30:1111-25. 2007
    ....
  61. ncbi Computer-based drug management in a bone marrow transplant unit: a suitable tool for multiple prescriptions even in critical conditions
    Mauro Krampera
    Department of Clinical and Experimental Medicine, Section of Haematology and Bone Marrow Transplant Unit Pharmacy Service, Policlinico Hospital Service of Informatics, Hospital Public System of Verona, Verona, Italy
    Br J Haematol 125:50-7. 2004
    ..In addition, it contributed to medical updating through warnings on potential problems in case of multiple drug prescriptions, and gave the pharmacy a valuable tool to monitor drug use...
  62. ncbi The safety of computer-based medication systems
    Mark Graber
    Arch Intern Med 164:339-40; author reply 340. 2004
  63. ncbi Improving recognition of drug interactions: benefits and barriers to using automated drug alerts
    Peter A Glassman
    VA HSR and D Center of Excellence for the Study of Healthcare Provider Behavior, VA Greater Los Angeles Healthcare System West Los Angeles Campus, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
    Med Care 40:1161-71. 2002
    ..Clinicians' perceptions about decision support systems may impact the effectiveness of these technologies...
  64. ncbi Prioritizing strategies for preventing medication errors and adverse drug events in pediatric inpatients
    Elizabeth B Fortescue
    Department of Medicine, Quality Improvement, and Risk Management, Children s Hospital, Boston, Massachusetts, USA
    Pediatrics 111:722-9. 2003
    ..The objective of this study was to classify the major types of medication errors in pediatric inpatients and to determine which strategies might most effectively prevent them...
  65. ncbi Specification of business rules for the development of hospital alarm system: application to the pharmaceutical validation
    Abdelali Boussadi
    INSERM UMR_S 872, Eq 20, Medicine Faculty Paris 5, France
    Stud Health Technol Inform 136:145-50. 2008
    ..We produced 3 business rules patterns and 427 instances of rules. As SBVR is close to natural language, pharmacists were able to understand rules and participate to their design...
  66. ncbi Critical intervention. Surgical ICU of a Utah academic hospital benefits from software's antibiotic recommendations and alerts
    Phil Reynolds
    Health Manag Technol 24:28-9. 2003
  67. ncbi The need for organizational change in patient safety initiatives
    James G Anderson
    Department of Sociology and Anthropology, Purdue University, West Lafayette, IN 47907 2059, USA
    Int J Med Inform 75:809-17. 2006
    ..This study describes a computer simulation model that has been developed to explore organizational changes required to improve patient safety based on a medication error reporting system...
  68. ncbi The epidemiology of prescribing errors: the potential impact of computerized prescriber order entry
    Anne Bobb
    Division of Operations and Quality, Patient Safety, Northwestern Memorial Hospital, Chicago, Ill, USA
    Arch Intern Med 164:785-92. 2004
    ..Adverse drug events (ADEs) are the most common cause of injury to hospitalized patients and are often preventable. Medication errors resulting in preventable ADEs most commonly occur at the prescribing stage...
  69. ncbi Securing chemotherapies: fabrication, prescription, administration and complete traceability
    Stéphane Spahni
    Service of Medical Informatics, Department of Radiology and Medical Informatics, University Hospitals of Geneva, Switzerland
    Stud Health Technol Inform 129:953-7. 2007
    ..This paper presents the overall approach leading the computerization of these processes and the first evaluations about the potential benefits of the computer-aided controls during the administration phase...
  70. pmc Using computer technology to detect, measure, and prevent adverse drug events
    Reed M Gardner
    J Am Med Inform Assoc 11:535-6. 2004
  71. pmc Characteristics and consequences of drug allergy alert overrides in a computerized physician order entry system
    Tyken C Hsieh
    Division of General Internal Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
    J Am Med Inform Assoc 11:482-91. 2004
    ..The aim of this study was to determine characteristics of drug allergy alert overrides, assess how often they lead to preventable adverse drug events (ADEs), and suggest methods for improving the allergy-alerting system...
  72. ncbi Pharmacists' role in assessing potential value of CPOE
    Sandra R Knowles
    Am J Health Syst Pharm 63:2182, 2184. 2006
  73. ncbi Detection and prevention of prescriptions with excessive doses in electronic prescribing systems
    H M Seidling
    Department of Internal Medicine VI, Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
    Eur J Clin Pharmacol 63:1185-92. 2007
    ....
  74. ncbi Development of case-based medication alerting and recommender system: a new approach to prevention for medication error
    Kengo Miyo
    Department of Planning, Information and Management, The University of Tokyo Hospital, Japan
    Stud Health Technol Inform 129:871-4. 2007
    ..Our system contributes to the creation of alerts that are appropriate for patients' clinical conditions and based on physicians' empirical discretion...
  75. ncbi Medication reconciliation using natural language processing and controlled terminologies
    James J Cimino
    Department of Biomedical Informatics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Stud Health Technol Inform 129:679-83. 2007
    ..This approach has implications for efforts to improve medication history-taking, order entry, and automated auditing of patient records for quality assurance...
  76. pmc A conceptual framework for evaluating outpatient electronic prescribing systems based on their functional capabilities
    Douglas S Bell
    RAND Health, Santa Monica, CA, USA
    J Am Med Inform Assoc 11:60-70. 2004
    ..The authors aimed to develop a conceptual framework for anticipating the effects of alternative designs for outpatient e-prescribing systems...
  77. pmc Improving prescribing using a rule based prescribing system
    C Anton
    West Midlands Centre for Adverse Drug Reaction Reporting, City Hospital, Birmingham B18 7QH, UK
    Qual Saf Health Care 13:186-90. 2004
    ..To test the hypothesis that the prescribing behaviour of doctors would improve after having experience with a computerised rule based prescribing system...
  78. ncbi Impact of emerging technologies on medication errors and adverse drug events
    Eyal Oren
    Department of Clinical Pharmacy, School of Pharmacy, University of California, San Francisco, USA
    Am J Health Syst Pharm 60:1447-58. 2003
    ..Very little evidence on the appropriateness of the use of these technologies was found...
  79. ncbi Methods for optimizing antiviral combination therapies
    Niko Beerenwinkel
    Max Planck Institute for Informatics, Stuhlsatzenhausweg 85, 66123 Saarbrucken, Germany
    Bioinformatics 19:i16-25. 2003
    ..The evolution of drug-resistant genetic variants in response to therapy plays a key role in treatment failure and finding a new potent drug combination after therapy failure is considered challenging...
  80. pmc E-prescribing: clinical implications for patients with diabetes
    Marie Smith
    University of Connecticut School of Pharmacy, Storrs, Connecticut 06269 3092, USA
    J Diabetes Sci Technol 3:1215-8. 2009
    ..This article presents three case studies that highlight common e-prescribing problems involving diabetes patients...
  81. ncbi Short-term diabetes blood glucose prediction based on blood glucose measurements
    F Stahl
    Department Automatic Control, Lund University, PO Box 118, Lund, SE22100 Sweden
    Conf Proc IEEE Eng Med Biol Soc 2008:291-4. 2008
    ..However, all the linear models shared some dynamics. Based on the estimated models, short-term blood glucose predictors for up to two-hour-ahead blood glucose prediction were investigated...
  82. ncbi Impact of an electronic antibiotic advice and approval system on antibiotic prescribing in an Australian teaching hospital
    M Lindsay Grayson
    Austin Health, Studley Road, Heidelberg, VIC 3084, Australia
    Med J Aust 180:455-8. 2004
    ..IDEA(3)S is a useful new adjunct to routine clinician consultation to support appropriate antibiotic prescribing for a number of common indications in hospitals...
  83. pmc Effect of alerts for drug dosage adjustment in inpatients with renal insufficiency
    Elodie Sellier
    Assistance Publique des Hôpitaux de Paris Georges Pompidou European Hospital, Medical Informatics and Public Health Department, and Paris Descartes University, Paris, France
    J Am Med Inform Assoc 16:203-10. 2009
    ....
  84. ncbi A diagnostic reasoning and optimal treatment model for bacterial infections with fuzzy information
    Han Ying Kao
    Department of Marketing and Distribution Management, Hsuan Chuang University, 48 Hsuan Chuang Road, Hsinchu 300, Taiwan
    Comput Methods Programs Biomed 77:23-37. 2005
    ....
  85. ncbi Quantitative lung perfusion scan as a predictor of aerosol distribution heterogeneity and disease severity in children with cystic fibrosis
    Emmanuel Itti
    Department of Nuclear Medicine, H Mondor Hospital, Assistance Publique Hopitaux de Paris, Paris XII University, Creteil, France
    Nucl Med Commun 25:563-9. 2004
    ..The assessment of lung ventilation by radionuclide imaging has proved useful for the optimization of aerosol therapy in children with cystic fibrosis. Further analysis of lung perfusion may provide additional information...
  86. ncbi Individualized duration of oral anticoagulant therapy for deep vein thrombosis based on a decision model
    R Vink
    Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
    J Thromb Haemost 1:2523-30. 2003
    ....
  87. pmc Comparative impact of guidelines, clinical data, and decision support on prescribing decisions: an interactive web experiment with simulated cases
    Vitali Sintchenko
    Centre for Health Informatics, University of New South Wales, Sydney 2052, Australia
    J Am Med Inform Assoc 11:71-7. 2004
    ..The aim of this study was to compare the clinical impact of computerized decision support with and without electronic access to clinical guidelines and laboratory data on antibiotic prescribing decisions...
  88. ncbi Lessons learned from a medication error
    Victoria Tamis
    Am J Health Syst Pharm 63:2186, 2188. 2006
  89. pmc Use of electronic monitoring in clinical nursing research
    Rita L Ailinger
    School of Nursing and Health Studies, Georgetown University, Washington, DC, USA
    Clin Nurs Res 17:89-97. 2008
    ..Nurses need to be aware of these challenges when using electronic measuring devices to monitor medication adherence in clinical nursing practice and research...
  90. ncbi Overrides of medication alerts in ambulatory care
    Thomas Isaac
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
    Arch Intern Med 169:305-11. 2009
    ..Electronic prescribing systems with decision support may improve patient safety in ambulatory care by offering drug allergy and drug interaction alerts. However, preliminary studies show that clinicians override most of these alerts...
  91. ncbi Optical method for real-time monitoring of drug concentrations facilitates the development of novel methods for drug delivery to brain tissue
    Roberto Reif
    Boston University, Department of Biomedical Engineering, 44 Cummington Street, Boston, Massachusetts 02215, USA
    J Biomed Opt 12:034036. 2007
    ..It is preliminarily determined in an animal model that the brain tissue uptake of chemotherapy agents-in this demonstration, MTX-delivered intra-arterially is enhanced when the BBB is disrupted...
  92. pmc Retrospective evaluation of a computerized physician order entry adaptation to prevent prescribing errors in a pediatric emergency department
    Brian E Sard
    Departments of Pediatric Emergency Medicine, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts, USA
    Pediatrics 122:782-7. 2008
    ..The goal was to determine the impact on medication prescribing errors of adding a pediatric medication list (quicklist) to a computerized physician order entry system in a pediatric emergency department...
  93. ncbi Artificial neural network prediction of clozapine response with combined pharmacogenetic and clinical data
    Chao Cheng Lin
    Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taiwan
    Comput Methods Programs Biomed 91:91-9. 2008
    ..805+/-0.056 versus 0.647+/-0.066; p=0.046). The gene polymorphisms should play an important role in the prediction. Further validation of ANN analysis is likely to provide decision support for predicting individual response...
  94. pmc A randomized trial of the effectiveness of on-demand versus computer-triggered drug decision support in primary care
    Robyn Tamblyn
    Department of Epidemiology and Biostatistics, McGill University, Morrice House, 1140 Pine Avenue West, Montreal Quebec, Canada, H3A 1A3
    J Am Med Inform Assoc 15:430-8. 2008
    ..Physicians in each study condition were able to preset levels that triggered alerts...
  95. ncbi DermaMan: scoring dermatology in your palm
    Bell Raj Eapen
    Kaya Skin Clinic, Dubai, United Arab Emirates
    Indian J Dermatol Venereol Leprol 74:424-6. 2008
    ..DermaMan is a freely available, Java-based, dermatology-specific calculator for handheld devices. It includes modules to compute PASI, MASI, SCORAD, and for calculations related to topical PUVA and Botox (R) administration...
  96. ncbi Modeling antitumor activity in xenograft tumor treatment
    Hua Liang
    St Jude Children s Research Hospital, USA
    Biom J 47:358-68. 2005
    ..We also propose an intuitive approach to a comparison of the antitumor effects of two different treatments. Biological interpretations and clinical implications are discussed...
  97. ncbi Comparison of computer integrated patient controlled epidural analgesia vs. conventional patient controlled epidural analgesia for pain relief in labour
    Y Lim
    Department of Women s Anaesthesia, KK Women s and Children s Hospital, Singapore
    Anaesthesia 61:339-44. 2006
    ..425). The CI-PCEA group had higher maternal satisfaction scores: mean (SD) 93 (7) vs. 86 (11), p = 0.042. CI-PCEA does not increase the use of local anaesthetic when compared with demand only PCEA but does increase patient satisfaction...
  98. ncbi Adaptive bolus-based targeted glucose regulation of hyperglycaemia in critical care
    J Geoffrey Chase
    Department of Mechanical Engineering, Centre for Bio Engineering, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
    Med Eng Phys 27:1-11. 2005
    ..The ability to track changing physiological status and account for insulin transport and effect saturation enabled targeted stepwise reduction in glycaemic levels in three test cases...
  99. ncbi Using technology to enhance measurement of drug-use safety
    Philip J Schneider
    Latiolais Leadership Program, College of Pharmacy, Ohio State University, 500 West 12th Avenue, Columbus, OH 43210, USA
    Am J Health Syst Pharm 59:2330-2. 2002
  100. ncbi Design of a computerized system for the retrospective analysis by the physician of his own drug prescriptions
    J H Liu
    EA2494, , , , France
    Stud Health Technol Inform 84:1175-9. 2001
    ..Some limitations and the possible extensions of this system for analyzing simultaneously the prescriptions made by set of physicians are discussed...
  101. ncbi Unintended effects of a computerized physician order entry nearly hard-stop alert to prevent a drug interaction: a randomized controlled trial
    Brian L Strom
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    Arch Intern Med 170:1578-83. 2010
    ..The effectiveness of computerized physician order entry (CPOE) systems has been modest, largely because clinicians frequently override electronic alerts...

Research Grants24

  1. Reducing Harm to Patients from Diagnostic Errors
    ETA BERNER; Fiscal Year: 2007
    ..To leverage AHRQ funding, additional support will be provided by registration fees, vendors, non-profit organizations and in-kind logistic support from the Society for Medical Decision Making. [unreadable] [unreadable] [unreadable]..
  2. Diabetes and Drug-Associated Hyperkalemia: Effect of Laboratory Monitoring
    Marsha Raebel; Fiscal Year: 2008
    ..The findings will also assist in developing a framework for future studies to evaluate the effects and costs of medication-laboratory monitoring among patients with diabetes. [unreadable] [unreadable] [unreadable] [unreadable]..
  3. Proactive Risk Reduction in Medication Prescribing in the Ambulatory Setting
    Terry Field; Fiscal Year: 2007
    ..3. Develop action plans for implementing identified interventions. [unreadable] [unreadable] [unreadable]..
  4. A Treatment Decision Modeling and Optimizing Technology
    Hao Ying; Fiscal Year: 2005
    ..It can be used to objectively and quantitatively analyze and compare different treatment options and selections, either prospectively or retrospectively. ..
  5. Impact of Medicaid Policy on cardiovascular drug use and clinical outcomes
    Michael A Fischer; Fiscal Year: 2010
    ....
  6. Clinical Knowledge Hub - Conceptual Integration of Rules, Data Sets, and Queries
    Gunther Schadow; Fiscal Year: 2010
    ....
  7. Modeling the Effect of Drugs in Intergomics by Linking Drug Ontology and Pathways
    Gunther Schadow; Fiscal Year: 2010
    ..This will allow researchers to understand better the effect which drugs have on the results of laboratory tests which measure a large number of proteins and chemicals in the body at the same time. ..
  8. REVAMP Follow-Up
    Madhukar Trivedi; Fiscal Year: 2008
    ....
  9. Modeling, Monitoring and Control of Hydrocephalus
    ANDREAS LINNINGER; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  10. Information Systems for Detecting and Managing Acute Kidney Injury
    Josh F Peterson; Fiscal Year: 2010
    ..The goal is to prevent AKI progression and the associated complications of hypokalemia, acidemia, and medication toxicity. ..
  11. MINORITY PREDOCTORAL FELLOWSHIP PROGRAM
    Roberto Reif; Fiscal Year: 2007
    ..Another application for the OP system will include detecting changes in capillary permeability caused by anti-angiogenic therapy. [unreadable] [unreadable] [unreadable]..
  12. Using Information Systems to Improve Cardiac Prevention
    Jeffrey Schnipper; Fiscal Year: 2007
    ..Schnipper's development as an independent researcher in improving the quality of care of patients with CAD. ..
  13. Computerized Decision Support System for Depression
    Madhukar Trivedi; Fiscal Year: 2007
    ..Comparisons will be made between CDSS-D, PPA-D, and UC-D. [unreadable] [unreadable]..
  14. VENLAFAXINE FOR HOT FLASHES FOLLOWING BREAST CANCER
    JANET CARPENTER; Fiscal Year: 2003
    ..e., t-tests, linear regression, GEE, mixed model). Study findings will significantly contribute to the scientific basis of hot flash management in women following treatment for breast cancer. ..
  15. Improving Transfusion Practices Using Decision Support
    Jeffrey Rothschild; Fiscal Year: 2004
    ..We will also examine whether improvements in appropriate transfusion ordering behavior among clinicians using decision support tools will be greater than improvements achieved by educational programs alone. ..
  16. Computerized Assessment of Cancer Symptoms
    JANET CARPENTER; Fiscal Year: 2005
    ....
  17. The Feasibility of Assessing the Prevalence of Rickets
    James Taylor; Fiscal Year: 2006
    ..In addition to assessing possible methodologies for the larger project, the preliminary study is designed to yield standalone results with important implications. [unreadable] [unreadable] [unreadable]..
  18. Treatment with Exercise Augmentation for Depression
    Madhukar Trivedi; Fiscal Year: 2006
    ....
  19. Value of New Drug Labeling Knowledge for e-Prescribing
    Gunther Schadow; Fiscal Year: 2006
    ..abstract_text> ..
  20. A RANDOMIZED CONTROLLED TRIAL OF ECHINACEA IN CHILDREN
    James Taylor; Fiscal Year: 2001
    ..abstract_text> ..
  21. Creighton Health Services Research Development Project
    Kimberly Galt; Fiscal Year: 2007
    ..Funding of this BRIC will facilitate the capacity needed to advance the Creighton University's health services research mission in a more rapid and sustainable fashion. [unreadable] [unreadable] [unreadable] [unreadable]..
  22. The Role of Cognitive Deficits in Chronic Heart Failure
    Susan Pressler; Fiscal Year: 2007
    ..The data obtained from this study are critically needed in order to design and test interventions for patients with HF whose care is complicated by cognitive deficits. ..
  23. MOMENT (Monitoring for Outpatient Medication Effects and New Toxicities) in TIME
    RANDOLPH MILLER; Fiscal Year: 2009
    ..The project will develop tools and algorithms to detect the patient symptoms, physical exam signs, test results, and medical diagnoses that may indicate drug-induced injury. ..
  24. Functional Neuroimaging of Cognitive Dysfunction in HIV-HCV Co-Infection
    Robert Paul; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..