computer assisted drug therapy
Summary: Adjunctive computer programs in providing drug treatment to patients.
Publications171 found, 100 shown here
- Computerized physician order entry and medication errors in a pediatric critical care unitAmy L Potts
Department of Pharmaceutical Services, Vanderbilt Children s Hospital, Nashville, Tennessee 37212 1565, USA
Pediatrics 113:59-63. 2004..The objective of this study was to evaluate the impact of CPOE on the frequency of errors in the medication ordering process in a pediatric critical care unit (PCCU)...
- Effects of computerized physician order entry and clinical decision support systems on medication safety: a systematic reviewRainu Kaushal
Division of General Internal Medicine, Brigham and Women s Hospital, Partners HealthCare System, Boston, Mass, USA
Arch Intern Med 163:1409-16. 2003..Iatrogenic injuries related to medications are common, costly, and clinically significant. Computerized physician order entry (CPOE) and clinical decision support systems (CDSSs) may reduce medication error rates...
- Improving ambulatory prescribing safety with a handheld decision support system: a randomized controlled trialEta S Berner
Department of Health Services Administration, University of Alabama at Birmingham, 1675 University Boulevard, Room 544, Birmingham, AL 35294 3361, USA
J Am Med Inform Assoc 13:171-9. 2006..To evaluate the effectiveness of a personal digital assistant (PDA)-based clinical decision support system (CDSS) on nonsteroidal anti-inflammatory drug (NSAID) prescribing safety in the outpatient setting...
- Computerized physician order entry: helpful or harmful?Robert G Berger
University of North Carolina School of Medicine, UNC Health Care System, CB 7280, Chapel Hill, NC 27599, USA
J Am Med Inform Assoc 11:100-3. 2004..Installation of such systems could actually increase the number of adverse drug events and result in higher overall medical costs, particularly in the first few years of their adoption...
- Medication errors: a prospective cohort study of hand-written and computerised physician order entry in the intensive care unitRob Shulman
Pharmacy Department, University College London Hospitals, Middlesex Hospital, London, UK
Crit Care 9:R516-21. 2005..The study aimed to compare the impact of computerised physician order entry (CPOE) without decision support with hand-written prescribing (HWP) on the frequency, type and outcome of medication errors (MEs) in the intensive care unit...
- The medical office of the 21st century (MOXXI): effectiveness of computerized decision-making support in reducing inappropriate prescribing in primary careRobyn Tamblyn
Department of Medicine, McGill University, Montreal, Que
CMAJ 169:549-56. 2003....
- Use of computerized decision support systems to improve antibiotic prescribingKarin Thursky
Infectious Diseases Physician, Centre for Clinical Research Excellence in Infectious Diseases, Victorian Infectious Diseases Service, Royal Melbourne Hospital, Grattan Street, Parkville, Victoria, 3051, Australia
Expert Rev Anti Infect Ther 4:491-507. 2006..This review describes computerized decision support systems used to assist with antibiotic prescribing, the evidence for their effectiveness and the current and future roles...
- The impact of computerized physician order entry on medication error preventionD W Bates
Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
J Am Med Inform Assoc 6:313-21. 1999..A small proportion do have the potential to cause injury, and some cause preventable adverse drug events...
- Effects of computerized physician order entry on prescribing practicesJ M Teich
Department of Emergency Medicine, Brigham and Women s Hospital, 75 Francis St, Boston, MA 02115
Arch Intern Med 160:2741-7. 2000..This study assesses the impact of an inpatient computerized physician order entry system on prescribing practices...
- A randomized controlled trial comparing a computer-assisted insulin infusion protocol with a strict and a conventional protocol for glucose control in critically ill patientsAlexandre B Cavalcanti
Intensive Care Unit, Hospital Israelita Albert Einstein, São Paulo 05652 000, Brazil
J Crit Care 24:371-8. 2009..The objective of this study is to evaluate blood glucose (BG) control efficacy and safety of 3 insulin protocols in medical intensive care unit (MICU) patients...
- Prescribers' responses to alerts during medication ordering in the long term care settingJames Judge
Meyers Primary Care Institute, 630 Plantation Street, Worcester, MA 01605, USA
J Am Med Inform Assoc 13:385-90. 2006....
- Dosage individualization of erythropoietin using a profile-dependent support vector regressionJosé David Martín-Guerrero
Digital Signal Processing Group, C Dr Moliner, 50 Dpt Eng Elec, Fac Física, Universitat de Valencia, Burjassot 46100, Spain
IEEE Trans Biomed Eng 50:1136-42. 2003..We perform sensitivity analysis on the MLP and inspect the distribution of the support vectors in the input and feature spaces in order to gain knowledge about the problem...
- Randomized trial to improve prescribing safety during pregnancyMarsha A Raebel
Kaiser Permanente Colorado Clinical Research Unit, PO Box 378066, Denver, CO 80237 8066, USA
J Am Med Inform Assoc 14:440-50. 2007..S. Food and Drug Administration pregnancy risk category D or X medications was effective in decreasing dispensings of these medications...
- A controlled trial of smart infusion pumps to improve medication safety in critically ill patientsJeffrey M Rothschild
Division of General Medicine and Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
Crit Care Med 33:533-40. 2005..We sought to assess the impact of smart pumps with integrated decision support software on the incidence and nature of medication errors and adverse drug events...
- Clinical decision support systems and antibiotic useNada Atef Shebl
Department of Practice and Policy, The School of Pharmacy, University of London, BMA House, Mezzanine Floor, Tavistock Square, London WC1H 9JP, UK
Pharm World Sci 29:342-9. 2007..To review and appraise randomised controlled trials (RCT) and 'before and after' studies published on clinical decision support systems (CDSS) used to support the use of antibiotics...
- Morbidity reduction in critically ill trauma patients through use of a computerized insulin infusion protocol: a preliminary studyEric A Toschlog
Department of Surgery, The Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834, USA
J Trauma 62:1370-5; discussion 1375-6. 2007..The purpose of our study was to evaluate the effect of a computerized hospital insulin protocol (CHIP) on glycemic control and outcome in critically ill trauma patients...
- Modeling and simulation of cancer immunoprevention vaccineF Pappalardo
Faculty of Pharmacy, University of Catania, Italy
Bioinformatics 21:2891-7. 2005..We present an in silico model that simulates the immune system responses to tumor cells in naive and vaccinated mice. We have demonstrated the ability of this model to accurately reproduce the experimental results...
- Improving empirical antibiotic treatment using TREAT, a computerized decision support system: cluster randomized trialMical Paul
Department of Medicine E, Rabin Medical Center, Beilinson Campus, 49100 Petah Tiqva, Israel
J Antimicrob Chemother 58:1238-45. 2006..Appropriate antibiotic treatment decreases mortality, while superfluous treatment is associated with antibiotic resistance. We built a computerized decision support system for antibiotic treatment (TREAT) targeting these outcomes...
- Tight glycaemic control by an automated algorithm with time-variant sampling in medical ICU patientsChristoph Pachler
Department of Internal Medicine, Medical University Graz, Stiftingtalstrasse 24, 8010, Graz, Austria
Intensive Care Med 34:1224-30. 2008....
- Failure of computerized treatment suggestions to improve health outcomes of outpatients with uncomplicated hypertension: results of a randomized controlled trialMichael D Murray
Department of Medicine, Indiana University School of Medicine, USA
Pharmacotherapy 24:324-37. 2004..To assess the effects of evidence-based treatment suggestions for hypertension made to physicians and pharmacists using a comprehensive electronic medical record system...
- Can computer-generated evidence-based care suggestions enhance evidence-based management of asthma and chronic obstructive pulmonary disease? A randomized, controlled trialWilliam M Tierney
Department of Medicine, Indiana University School of Medicine, M200 OPW, Wishard Memorial Hospital, 1001 West 10th St, Indianapolis, IN 46202, USA
Health Serv Res 40:477-97. 2005..Translation of evidence-based guidelines into clinical practice has been inconsistent. We performed a randomized, controlled trial of guideline-based care suggestions delivered to physicians when writing orders on computer workstations...
- Computer-based insulin infusion protocol improves glycemia control over manual protocolJeffrey B Boord
Vanderbilt University, Division of Cardiovascular Medicine, Nashville, TN 37232 8802, USA
J Am Med Inform Assoc 14:278-87. 2007....
- Clinical decision support in electronic prescribing: recommendations and an action plan: report of the joint clinical decision support workgroupJonathan M Teich
Department of Emergency Medicine, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
J Am Med Inform Assoc 12:365-76. 2005....
- Impact of computerized physician order entry on clinical practice in a newborn intensive care unitLeandro Cordero
Pediatrics and Obstetrics, The Ohio State University Medical Center, Columbus, OH 43210, USA
J Perinatol 24:88-93. 2004..To study the impact of computerized physician order entry (CPOE) on selected neonatal intensive care unit (NICU) practices...
- A replicable method for blood glucose control in critically Ill patientsAlan H Morris
Pulmonary Division, Department of Medicine, LDS Hospital and the University of Utah School of Medicine, Salt Lake City, UT, USA
Crit Care Med 36:1787-95. 2008..To ensure interpretability and replicability of clinical experiments, methods must be adequately explicit and should elicit the same decision from different clinicians who comply with the study protocol...
- Implementation of a tight glycaemic control protocol using a web-based insulin dose calculatorA N Thomas
Intensive Care Unit, Hope Hospital, Stott Lane, Salford, M6 8HD, UK
Anaesthesia 60:1093-100. 2005..19-3.73] compared to values < 6.1 mmol.l(-1). However, patient mortality remained constant during the study. Glycaemic control was improved outside a research setting using a protocol supported by a web-based insulin dose calculator...
- Use of a computer-based reminder to improve sedative-hypnotic prescribing in older hospitalized patientsJoseph V Agostini
Clinical Epidemiology Research Center, VA Connecticut Healthcare Center, West Haven, CT 06516, USA
J Am Geriatr Soc 55:43-8. 2007..To develop a feasible, inexpensive, point-of-care computerized reminder to improve sedative-hypnotic prescribing in hospitalized older people...
- Computer decision support systemsT H Payne
VA Puget Sound Health Care System, University of Washington, Seattle, WA 98108, USA
Chest 118:47S-52S. 2000..As computer-based records and order-entry systems become more common, automated decision support systems will be used more broadly...
- Design of a safer approach to intravenous drug infusions: failure mode effects analysisM Apkon
333 Cedar Street, New Haven, CT 06520 8064, USA
Qual Saf Health Care 13:265-71. 2004..Failure modes effects analysis (FMEA) was used to examine the impact of process changes on the reliability of delivering drug infusions...
- Active insulin infusion using optimal and derivative-weighted controlZ H Lam
Department of Mechanical Engineering, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
Med Eng Phys 24:663-72. 2002..Overall, emerging blood glucose sensor technologies that enable frequent measurement are shown to enable more effective, automated control of blood glucose levels within a tight, acceptable range for Type I and II diabetic individuals...
- Comparison of percutaneous acetic acid injection and percutaneous ethanol injection for hepatocellular carcinoma in cirrhotic patients: a prospective studyT I Huo
Division of Gastroenterology, Dept of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, Republic of China
Scand J Gastroenterol 38:770-8. 2003..We conducted a prospective study to compare the therapeutic efficacy of both these methods...
- An intravenous medication safety system: preventing high-risk medication errors at the point of careIrene Hatcher
Case Management, Vanderbilt University Medical Center, 1161 21st Avenue S, Nashville, TN 37232 2415, USA
J Nurs Adm 34:437-9. 2004....
- Improving acceptance of computerized prescribing alerts in ambulatory careNidhi R Shah
Division of General Medicine, Brigham and Women s Hospital, 1620 Tremont Street, 3rd Floor, Boston, MA 02120, USA
J Am Med Inform Assoc 13:5-11. 2006..These data suggest that it is possible to design computerized prescribing decision support with high rates of alert recommendation acceptance by clinicians...
- A trial of automated decision support alerts for contraindicated medications using computerized physician order entryWilliam L Galanter
University of Illinois at Chicago, Department of Medicine, Section of General Internal Medicine M C 718, 840 S Wood St, Chicago, IL 60612, USA
J Am Med Inform Assoc 12:269-74. 2005..Because renal insufficiency is a common source of medication errors, the authors studied a trial of alerts designed to reduce inpatient administration of medications contraindicated due to renal insufficiency...
- Effect of computerisation on the quality and safety of chemotherapy prescriptionMarc Voeffray
Pharmacy Service, University Hospital, Lausanne, Switzerland
Qual Saf Health Care 15:418-21. 2006..Multiple errors can occur during the prescription, the transmission of documents and the drug delivery processes, and lead to potentially serious consequences...
- [Clinical decision support: Is the number of medication errors reduced?]Louise Isager Rabøl
H S Hvidovre Hospital, Dansk Selskab for Patientsikkerhed, København
Ugeskr Laeger 168:4179-84. 2006..CPOE with CDS is time consuming and may generate new medication errors in itself. All the trials had poor designs. A Danish data source for CDS has not yet been established...
- Ten simple strategies to prevent chemotherapy errorsLisa Schulmeister
Clin J Oncol Nurs 9:201-5. 2005..These strategies can be customized for use in a variety of practice settings. Oncology nurses are at the forefront of chemotherapy error-prevention initiatives and play a key role in implementing safety measures...
- Medication-error reporting and pharmacy resident experience during implementation of computerized prescriber order entryKyle A Weant
Department of Pharmacy, University of North Carolina Hospitals, 101 Manning Drive, Chapel Hill, NC 27514, USA
Am J Health Syst Pharm 64:526-30. 2007....
- Personal digital assistant-based drug information sources: potential to improve medication safetyKimberly A Galt
Department of Pharmacy Practice, School of Pharmacy and Health Professions, Creighton University, 2500 California Plaza, Omaha, Nebraska 68178, USA
J Med Libr Assoc 93:229-36. 2005..This study compared the potential for personal digital assistant (PDA)-based drug information sources to minimize potential medication errors dependent on accurate and complete drug information at the point of care...
- Prescribing errors resulting in adverse drug events: how can they be prevented?Petra A Thürmann
Expert Opin Drug Saf 5:489-93. 2006..However, these systems still have some shortcomings and it has not yet convincingly been shown that the use of this technology really improves patient safety...
- The development and evaluation of an integrated electronic prescribing and drug management system for primary careRobyn Tamblyn
Department of Epidemiology and Biostatistics, McGill University, Morrice House, 1140 Pine Avenue West, Montreal, Quebec, Canada H3A 1A3
J Am Med Inform Assoc 13:148-59. 2006..To develop and evaluate the acceptability and use of an integrated electronic prescribing and drug management system (MOXXI) for primary care physicians...
- Automated medication error studies with audit supplementation were effectively designed and analyzed by time seriesJonathan J Shuster
Department of Epidemiology and Health Policy Research, College of Medicine, University of Florida, 1600 W Archer Raod, 100212, Gainesville, FL 32610 0212, USA
J Clin Epidemiol 59:957-63. 2006..To provide researchers with an efficient yet methodologically robust method to design and analyze studies of the effectiveness of quality improvement interventions targeted at medical errors...
- First do no harm: Hamilton Health Sciences' experience as first hospital in the world to fully implement Medley Medication Safety SystemPaul Faguy
Hamilton Health Sciences
Healthc Q 8:116-9. 2005
- What do we know about medication errors made via a CPOE system versus those made via handwritten orders?Ross Koppel
Center for Clinical Epidemiology and Biostatistics, School of Medicine, and Sociology Department, University of Pennsylvania, Philadelphia, PA, USA
Crit Care 9:427-8. 2005..I discuss these issues and their implications for the evaluation of CPOE systems and of other emerging healthcare technologies...
- High rates of adverse drug events in a highly computerized hospitalJonathan R Nebeker
Veterans Administration Salt Lake City Health Care System, Geriatric Research, Education, and Clinical Center, Salt Lake City, Utah, USA
Arch Intern Med 165:1111-6. 2005..We describe the frequency and type of inpatient ADEs that occurred following the adoption of multiple computerized medication ordering and administration systems, including computerized physician order entry (CPOE)...
- Effect of a remote order scanning system on processing medication ordersSamir Sikri
Professional Services, MarketRx, Gurgaon, India
Am J Health Syst Pharm 63:1438-41. 2006
- Medication-related clinical decision support in computerized provider order entry systems: a reviewGilad J Kuperman
Quality Informatics, NewYork Presbyterian Hospital, 525 E 68 Street, Box 298, New York, NY 10021, USA
J Am Med Inform Assoc 14:29-40. 2007..The authors conclude with summary recommendations for delivering effective medication-related clinical decision support addressed to healthcare organizations, application and knowledge base vendors, policy makers, and researchers...
- Compelling features of a safe medication-use systemWilliam N Kelly
William N Kelly Consulting, Inc, Oldsmar, FL 34677, USA
Am J Health Syst Pharm 63:1461-8. 2006
- Detection and prevention of medication errors using real-time bedside nurse chartingNancy C Nelson
Department of Medical Informatics, LDS Hospital, Salt Lake City, UT 84143, USA
J Am Med Inform Assoc 12:390-7. 2005..The aim of this study was to increase the real-time bedside charting behavior of nurses...
- Reducing excessive medication administration in hospitalized adults with renal dysfunctionIra S Nash
Zena and Michael A Wiener Cardiovascular Institute and The Marie Josée and Henry R Kravis Center for Cardiovascular Health, Mount Sinai Medical Center, New York, NY 10029, USA
Am J Med Qual 20:64-9. 2005..1% and 24.8% in the rest of the hospital. Automated detection and routine feedback can reduce the rate of excessive administration of medication in hospitalized adults with renal insufficiency...
- [Frequency, relevance, causes of and strategies for prevention of medication errors]D Grandt
Medizinische Klinik I, Klinikum Saarbrücken, Winterberg 1, 66130, Saarbrucken, Germany
Z Gerontol Geriatr 38:196-202. 2005..Studies have demonstrated that CPOES can reduce medication errors by 80%. The necessary steps to improve medication safety in Germany are outlined and discussed...
- Computer-supported weight-based drug infusion concentrations in the neonatal intensive care unitGay Giannone
Siemens Health Systems, Malvern, PA 19355, USA
Comput Inform Nurs 23:100-5. 2005..In addition, the article provides guidelines on how to customize a vendor solution for hospitals with neonatal intensive care unit...
- Incorporation of a gentamicin dosage calculator into a computerized prescriber-order-entry systemAgnes L F Chan
Department of Pharmacy, Chi Mei Medical Center, Tainan, Taiwan
Am J Health Syst Pharm 63:1344-5. 2006
- Clinical decision support and electronic prescribing systems: a time for responsible thought and actionRandolph A Miller
Department of Biomedical Informatics, Vanderbilt University, Nashville, TN, USA
J Am Med Inform Assoc 12:403-9. 2005
- Medication errors in inpatient pharmacy operations and technologies for improvementSeth Alan Kuiper
University of Michigan Hospitals and Health Centers, Ann Arbor, USA
Am J Health Syst Pharm 64:955-9. 2007
- Randomized trial to improve prescribing safety in ambulatory elderly patientsMarsha A Raebel
Clinical Research Unit, Kaiser Permanente Colorado, Denver, Colorado 80237 8066, USA
J Am Geriatr Soc 55:977-85. 2007....
- A trial of automated safety alerts for inpatient digoxin use with computerized physician order entryWilliam L Galanter
Department of Medicine, Section of General Internal Medicine M C 718, University of Illinois at Chicago, 840 South Wood Street, Chicago, IL 60612, USA
J Am Med Inform Assoc 11:270-7. 2004....
- Development of a pharmacy-managed medication dictionary in a newly implemented computerized prescriber order-entry systemDiane Soulliard
Department of Pharmacy, Beth Israel Deaconess Medical Center, 1 Deaconess Road, Boston, MA 02215, USA
Am J Health Syst Pharm 61:617-22. 2004
- Preventing provider errors: online total parenteral nutrition calculatorChristoph U Lehmann
Division of Neonatology, Department of Pediatrics, Johns Hopkins University, Baltimore, Maryland 21287 3200, USA
Pediatrics 113:748-53. 2004..To describe the development of a pragmatic low-cost medical information system that reduces errors in the ordering of total parenteral nutrition (TPN) in the newborn intensive care unit at the Johns Hopkins Hospital...
- Interventions to reduce dosing errors in children: a systematic review of the literatureSharon Conroy
Academic Division of Child Health, Derbyshire Children s Hospital, University of Nottingham, Nottingham, UK
Drug Saf 30:1111-25. 2007....
- Computer-based drug management in a bone marrow transplant unit: a suitable tool for multiple prescriptions even in critical conditionsMauro Krampera
Department of Clinical and Experimental Medicine, Section of Haematology and Bone Marrow Transplant Unit Pharmacy Service, Policlinico Hospital Service of Informatics, Hospital Public System of Verona, Verona, Italy
Br J Haematol 125:50-7. 2004..In addition, it contributed to medical updating through warnings on potential problems in case of multiple drug prescriptions, and gave the pharmacy a valuable tool to monitor drug use...
- The safety of computer-based medication systemsMark Graber
Arch Intern Med 164:339-40; author reply 340. 2004
- Improving recognition of drug interactions: benefits and barriers to using automated drug alertsPeter A Glassman
VA HSR and D Center of Excellence for the Study of Healthcare Provider Behavior, VA Greater Los Angeles Healthcare System West Los Angeles Campus, 11301 Wilshire Boulevard, Los Angeles, CA 90073, USA
Med Care 40:1161-71. 2002..Clinicians' perceptions about decision support systems may impact the effectiveness of these technologies...
- Prioritizing strategies for preventing medication errors and adverse drug events in pediatric inpatientsElizabeth B Fortescue
Department of Medicine, Quality Improvement, and Risk Management, Children s Hospital, Boston, Massachusetts, USA
Pediatrics 111:722-9. 2003..The objective of this study was to classify the major types of medication errors in pediatric inpatients and to determine which strategies might most effectively prevent them...
- Specification of business rules for the development of hospital alarm system: application to the pharmaceutical validationAbdelali Boussadi
INSERM UMR_S 872, Eq 20, Medicine Faculty Paris 5, France
Stud Health Technol Inform 136:145-50. 2008..We produced 3 business rules patterns and 427 instances of rules. As SBVR is close to natural language, pharmacists were able to understand rules and participate to their design...
- Critical intervention. Surgical ICU of a Utah academic hospital benefits from software's antibiotic recommendations and alertsPhil Reynolds
Health Manag Technol 24:28-9. 2003
- The need for organizational change in patient safety initiativesJames G Anderson
Department of Sociology and Anthropology, Purdue University, West Lafayette, IN 47907 2059, USA
Int J Med Inform 75:809-17. 2006..This study describes a computer simulation model that has been developed to explore organizational changes required to improve patient safety based on a medication error reporting system...
- The epidemiology of prescribing errors: the potential impact of computerized prescriber order entryAnne Bobb
Division of Operations and Quality, Patient Safety, Northwestern Memorial Hospital, Chicago, Ill, USA
Arch Intern Med 164:785-92. 2004..Adverse drug events (ADEs) are the most common cause of injury to hospitalized patients and are often preventable. Medication errors resulting in preventable ADEs most commonly occur at the prescribing stage...
- Securing chemotherapies: fabrication, prescription, administration and complete traceabilityStéphane Spahni
Service of Medical Informatics, Department of Radiology and Medical Informatics, University Hospitals of Geneva, Switzerland
Stud Health Technol Inform 129:953-7. 2007..This paper presents the overall approach leading the computerization of these processes and the first evaluations about the potential benefits of the computer-aided controls during the administration phase...
- Using computer technology to detect, measure, and prevent adverse drug eventsReed M Gardner
J Am Med Inform Assoc 11:535-6. 2004
- Characteristics and consequences of drug allergy alert overrides in a computerized physician order entry systemTyken C Hsieh
Division of General Internal Medicine, Brigham and Women s Hospital, Boston, MA 02120, USA
J Am Med Inform Assoc 11:482-91. 2004..The aim of this study was to determine characteristics of drug allergy alert overrides, assess how often they lead to preventable adverse drug events (ADEs), and suggest methods for improving the allergy-alerting system...
- Pharmacists' role in assessing potential value of CPOESandra R Knowles
Am J Health Syst Pharm 63:2182, 2184. 2006
- Detection and prevention of prescriptions with excessive doses in electronic prescribing systemsH M Seidling
Department of Internal Medicine VI, Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120 Heidelberg, Germany
Eur J Clin Pharmacol 63:1185-92. 2007....
- Development of case-based medication alerting and recommender system: a new approach to prevention for medication errorKengo Miyo
Department of Planning, Information and Management, The University of Tokyo Hospital, Japan
Stud Health Technol Inform 129:871-4. 2007..Our system contributes to the creation of alerts that are appropriate for patients' clinical conditions and based on physicians' empirical discretion...
- Medication reconciliation using natural language processing and controlled terminologiesJames J Cimino
Department of Biomedical Informatics, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
Stud Health Technol Inform 129:679-83. 2007..This approach has implications for efforts to improve medication history-taking, order entry, and automated auditing of patient records for quality assurance...
- A conceptual framework for evaluating outpatient electronic prescribing systems based on their functional capabilitiesDouglas S Bell
RAND Health, Santa Monica, CA, USA
J Am Med Inform Assoc 11:60-70. 2004..The authors aimed to develop a conceptual framework for anticipating the effects of alternative designs for outpatient e-prescribing systems...
- Improving prescribing using a rule based prescribing systemC Anton
West Midlands Centre for Adverse Drug Reaction Reporting, City Hospital, Birmingham B18 7QH, UK
Qual Saf Health Care 13:186-90. 2004..To test the hypothesis that the prescribing behaviour of doctors would improve after having experience with a computerised rule based prescribing system...
- Impact of emerging technologies on medication errors and adverse drug eventsEyal Oren
Department of Clinical Pharmacy, School of Pharmacy, University of California, San Francisco, USA
Am J Health Syst Pharm 60:1447-58. 2003..Very little evidence on the appropriateness of the use of these technologies was found...
- Methods for optimizing antiviral combination therapiesNiko Beerenwinkel
Max Planck Institute for Informatics, Stuhlsatzenhausweg 85, 66123 Saarbrucken, Germany
Bioinformatics 19:i16-25. 2003..The evolution of drug-resistant genetic variants in response to therapy plays a key role in treatment failure and finding a new potent drug combination after therapy failure is considered challenging...
- E-prescribing: clinical implications for patients with diabetesMarie Smith
University of Connecticut School of Pharmacy, Storrs, Connecticut 06269 3092, USA
J Diabetes Sci Technol 3:1215-8. 2009..This article presents three case studies that highlight common e-prescribing problems involving diabetes patients...
- Short-term diabetes blood glucose prediction based on blood glucose measurementsF Stahl
Department Automatic Control, Lund University, PO Box 118, Lund, SE22100 Sweden
Conf Proc IEEE Eng Med Biol Soc 2008:291-4. 2008..However, all the linear models shared some dynamics. Based on the estimated models, short-term blood glucose predictors for up to two-hour-ahead blood glucose prediction were investigated...
- Impact of an electronic antibiotic advice and approval system on antibiotic prescribing in an Australian teaching hospitalM Lindsay Grayson
Austin Health, Studley Road, Heidelberg, VIC 3084, Australia
Med J Aust 180:455-8. 2004..IDEA(3)S is a useful new adjunct to routine clinician consultation to support appropriate antibiotic prescribing for a number of common indications in hospitals...
- Effect of alerts for drug dosage adjustment in inpatients with renal insufficiencyElodie Sellier
Assistance Publique des Hôpitaux de Paris Georges Pompidou European Hospital, Medical Informatics and Public Health Department, and Paris Descartes University, Paris, France
J Am Med Inform Assoc 16:203-10. 2009....
- A diagnostic reasoning and optimal treatment model for bacterial infections with fuzzy informationHan Ying Kao
Department of Marketing and Distribution Management, Hsuan Chuang University, 48 Hsuan Chuang Road, Hsinchu 300, Taiwan
Comput Methods Programs Biomed 77:23-37. 2005....
- Quantitative lung perfusion scan as a predictor of aerosol distribution heterogeneity and disease severity in children with cystic fibrosisEmmanuel Itti
Department of Nuclear Medicine, H Mondor Hospital, Assistance Publique Hopitaux de Paris, Paris XII University, Creteil, France
Nucl Med Commun 25:563-9. 2004..The assessment of lung ventilation by radionuclide imaging has proved useful for the optimization of aerosol therapy in children with cystic fibrosis. Further analysis of lung perfusion may provide additional information...
- Individualized duration of oral anticoagulant therapy for deep vein thrombosis based on a decision modelR Vink
Department of Vascular Medicine, Academic Medical Center, University of Amsterdam, The Netherlands
J Thromb Haemost 1:2523-30. 2003....
- Comparative impact of guidelines, clinical data, and decision support on prescribing decisions: an interactive web experiment with simulated casesVitali Sintchenko
Centre for Health Informatics, University of New South Wales, Sydney 2052, Australia
J Am Med Inform Assoc 11:71-7. 2004..The aim of this study was to compare the clinical impact of computerized decision support with and without electronic access to clinical guidelines and laboratory data on antibiotic prescribing decisions...
- Lessons learned from a medication errorVictoria Tamis
Am J Health Syst Pharm 63:2186, 2188. 2006
- Use of electronic monitoring in clinical nursing researchRita L Ailinger
School of Nursing and Health Studies, Georgetown University, Washington, DC, USA
Clin Nurs Res 17:89-97. 2008..Nurses need to be aware of these challenges when using electronic measuring devices to monitor medication adherence in clinical nursing practice and research...
- Overrides of medication alerts in ambulatory careThomas Isaac
Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
Arch Intern Med 169:305-11. 2009..Electronic prescribing systems with decision support may improve patient safety in ambulatory care by offering drug allergy and drug interaction alerts. However, preliminary studies show that clinicians override most of these alerts...
- Optical method for real-time monitoring of drug concentrations facilitates the development of novel methods for drug delivery to brain tissueRoberto Reif
Boston University, Department of Biomedical Engineering, 44 Cummington Street, Boston, Massachusetts 02215, USA
J Biomed Opt 12:034036. 2007..It is preliminarily determined in an animal model that the brain tissue uptake of chemotherapy agents-in this demonstration, MTX-delivered intra-arterially is enhanced when the BBB is disrupted...
- Retrospective evaluation of a computerized physician order entry adaptation to prevent prescribing errors in a pediatric emergency departmentBrian E Sard
Departments of Pediatric Emergency Medicine, Boston University School of Medicine and Boston Medical Center, Boston, Massachusetts, USA
Pediatrics 122:782-7. 2008..The goal was to determine the impact on medication prescribing errors of adding a pediatric medication list (quicklist) to a computerized physician order entry system in a pediatric emergency department...
- Artificial neural network prediction of clozapine response with combined pharmacogenetic and clinical dataChao Cheng Lin
Graduate Institute of Medical Sciences, College of Medicine, Taipei Medical University, Taiwan
Comput Methods Programs Biomed 91:91-9. 2008..805+/-0.056 versus 0.647+/-0.066; p=0.046). The gene polymorphisms should play an important role in the prediction. Further validation of ANN analysis is likely to provide decision support for predicting individual response...
- A randomized trial of the effectiveness of on-demand versus computer-triggered drug decision support in primary careRobyn Tamblyn
Department of Epidemiology and Biostatistics, McGill University, Morrice House, 1140 Pine Avenue West, Montreal Quebec, Canada, H3A 1A3
J Am Med Inform Assoc 15:430-8. 2008..Physicians in each study condition were able to preset levels that triggered alerts...
- DermaMan: scoring dermatology in your palmBell Raj Eapen
Kaya Skin Clinic, Dubai, United Arab Emirates
Indian J Dermatol Venereol Leprol 74:424-6. 2008..DermaMan is a freely available, Java-based, dermatology-specific calculator for handheld devices. It includes modules to compute PASI, MASI, SCORAD, and for calculations related to topical PUVA and Botox (R) administration...
- Modeling antitumor activity in xenograft tumor treatmentHua Liang
St Jude Children s Research Hospital, USA
Biom J 47:358-68. 2005..We also propose an intuitive approach to a comparison of the antitumor effects of two different treatments. Biological interpretations and clinical implications are discussed...
- Comparison of computer integrated patient controlled epidural analgesia vs. conventional patient controlled epidural analgesia for pain relief in labourY Lim
Department of Women s Anaesthesia, KK Women s and Children s Hospital, Singapore
Anaesthesia 61:339-44. 2006..425). The CI-PCEA group had higher maternal satisfaction scores: mean (SD) 93 (7) vs. 86 (11), p = 0.042. CI-PCEA does not increase the use of local anaesthetic when compared with demand only PCEA but does increase patient satisfaction...
- Adaptive bolus-based targeted glucose regulation of hyperglycaemia in critical careJ Geoffrey Chase
Department of Mechanical Engineering, Centre for Bio Engineering, University of Canterbury, Private Bag 4800, Christchurch, New Zealand
Med Eng Phys 27:1-11. 2005..The ability to track changing physiological status and account for insulin transport and effect saturation enabled targeted stepwise reduction in glycaemic levels in three test cases...
- Using technology to enhance measurement of drug-use safetyPhilip J Schneider
Latiolais Leadership Program, College of Pharmacy, Ohio State University, 500 West 12th Avenue, Columbus, OH 43210, USA
Am J Health Syst Pharm 59:2330-2. 2002
- Design of a computerized system for the retrospective analysis by the physician of his own drug prescriptionsJ H Liu
EA2494, , , , France
Stud Health Technol Inform 84:1175-9. 2001..Some limitations and the possible extensions of this system for analyzing simultaneously the prescriptions made by set of physicians are discussed...
- Unintended effects of a computerized physician order entry nearly hard-stop alert to prevent a drug interaction: a randomized controlled trialBrian L Strom
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
Arch Intern Med 170:1578-83. 2010..The effectiveness of computerized physician order entry (CPOE) systems has been modest, largely because clinicians frequently override electronic alerts...
- Reducing Harm to Patients from Diagnostic ErrorsETA BERNER; Fiscal Year: 2007..To leverage AHRQ funding, additional support will be provided by registration fees, vendors, non-profit organizations and in-kind logistic support from the Society for Medical Decision Making. [unreadable] [unreadable] [unreadable]..
- Diabetes and Drug-Associated Hyperkalemia: Effect of Laboratory MonitoringMarsha Raebel; Fiscal Year: 2008..The findings will also assist in developing a framework for future studies to evaluate the effects and costs of medication-laboratory monitoring among patients with diabetes. [unreadable] [unreadable] [unreadable] [unreadable]..
- Proactive Risk Reduction in Medication Prescribing in the Ambulatory SettingTerry Field; Fiscal Year: 2007..3. Develop action plans for implementing identified interventions. [unreadable] [unreadable] [unreadable]..
- A Treatment Decision Modeling and Optimizing TechnologyHao Ying; Fiscal Year: 2005..It can be used to objectively and quantitatively analyze and compare different treatment options and selections, either prospectively or retrospectively. ..
- Impact of Medicaid Policy on cardiovascular drug use and clinical outcomesMichael A Fischer; Fiscal Year: 2010....
- Clinical Knowledge Hub - Conceptual Integration of Rules, Data Sets, and QueriesGunther Schadow; Fiscal Year: 2010....
- Modeling the Effect of Drugs in Intergomics by Linking Drug Ontology and PathwaysGunther Schadow; Fiscal Year: 2010..This will allow researchers to understand better the effect which drugs have on the results of laboratory tests which measure a large number of proteins and chemicals in the body at the same time. ..
- REVAMP Follow-UpMadhukar Trivedi; Fiscal Year: 2008....
- Modeling, Monitoring and Control of HydrocephalusANDREAS LINNINGER; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Information Systems for Detecting and Managing Acute Kidney InjuryJosh F Peterson; Fiscal Year: 2010..The goal is to prevent AKI progression and the associated complications of hypokalemia, acidemia, and medication toxicity. ..
- MINORITY PREDOCTORAL FELLOWSHIP PROGRAMRoberto Reif; Fiscal Year: 2007..Another application for the OP system will include detecting changes in capillary permeability caused by anti-angiogenic therapy. [unreadable] [unreadable] [unreadable]..
- Using Information Systems to Improve Cardiac PreventionJeffrey Schnipper; Fiscal Year: 2007..Schnipper's development as an independent researcher in improving the quality of care of patients with CAD. ..
- Computerized Decision Support System for DepressionMadhukar Trivedi; Fiscal Year: 2007..Comparisons will be made between CDSS-D, PPA-D, and UC-D. [unreadable] [unreadable]..
- VENLAFAXINE FOR HOT FLASHES FOLLOWING BREAST CANCERJANET CARPENTER; Fiscal Year: 2003..e., t-tests, linear regression, GEE, mixed model). Study findings will significantly contribute to the scientific basis of hot flash management in women following treatment for breast cancer. ..
- Improving Transfusion Practices Using Decision SupportJeffrey Rothschild; Fiscal Year: 2004..We will also examine whether improvements in appropriate transfusion ordering behavior among clinicians using decision support tools will be greater than improvements achieved by educational programs alone. ..
- Computerized Assessment of Cancer SymptomsJANET CARPENTER; Fiscal Year: 2005....
- The Feasibility of Assessing the Prevalence of RicketsJames Taylor; Fiscal Year: 2006..In addition to assessing possible methodologies for the larger project, the preliminary study is designed to yield standalone results with important implications. [unreadable] [unreadable] [unreadable]..
- Treatment with Exercise Augmentation for DepressionMadhukar Trivedi; Fiscal Year: 2006....
- Value of New Drug Labeling Knowledge for e-PrescribingGunther Schadow; Fiscal Year: 2006..abstract_text> ..
- A RANDOMIZED CONTROLLED TRIAL OF ECHINACEA IN CHILDRENJames Taylor; Fiscal Year: 2001..abstract_text> ..
- Creighton Health Services Research Development ProjectKimberly Galt; Fiscal Year: 2007..Funding of this BRIC will facilitate the capacity needed to advance the Creighton University's health services research mission in a more rapid and sustainable fashion. [unreadable] [unreadable] [unreadable] [unreadable]..
- The Role of Cognitive Deficits in Chronic Heart FailureSusan Pressler; Fiscal Year: 2007..The data obtained from this study are critically needed in order to design and test interventions for patients with HF whose care is complicated by cognitive deficits. ..
- MOMENT (Monitoring for Outpatient Medication Effects and New Toxicities) in TIMERANDOLPH MILLER; Fiscal Year: 2009..The project will develop tools and algorithms to detect the patient symptoms, physical exam signs, test results, and medical diagnoses that may indicate drug-induced injury. ..
- Functional Neuroimaging of Cognitive Dysfunction in HIV-HCV Co-InfectionRobert Paul; Fiscal Year: 2006..unreadable] [unreadable] [unreadable]..