drainage

Summary

Summary: The removal of fluids or discharges from the body, such as from a wound, sore, or cavity.

Top Publications

  1. doi Unilateral versus bilateral endoscopic metal stenting for malignant hilar biliary obstruction
    Itaru Naitoh
    Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    J Gastroenterol Hepatol 24:552-7. 2009
  2. pmc Intra-abdominal pressure alterations after large pancreatic pseudocyst transcutaneous drainage
    Theodossis S Papavramidis
    1st Propedeutic Department of Surgery, AHEPA University Hospital, Aristotle s University of Thessaloniki, Macedonia, Greece
    BMC Gastroenterol 9:42. 2009
  3. doi Endoscopic ultrasound-guided versus conventional transmural drainage for pancreatic pseudocysts: a prospective randomized trial
    D H Park
    Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Songpa Gu, 138 736, Seoul, South Korea
    Endoscopy 41:842-8. 2009
  4. ncbi Seroma following breast cancer surgery
    C J Pogson
    Breast Unit, Mayday University Hospital, London Road, Croydon CR7 7YE, UK
    Eur J Surg Oncol 29:711-7. 2003
  5. ncbi The addition of manual lymph drainage to compression therapy for breast cancer related lymphedema: a randomized controlled trial
    Margaret L McNeely
    Department of Rehabilitation Medicine, Cross Cancer Institute, Edmonton, Alberta, Canada
    Breast Cancer Res Treat 86:95-106. 2004
  6. doi A step-up approach or open necrosectomy for necrotizing pancreatitis
    Hjalmar C van Santvoort
    University Medical Center, Utrecht, The Netherlands
    N Engl J Med 362:1491-502. 2010
  7. doi PleurX peritoneal catheter drainage system for vacuum-assisted drainage of treatment-resistant, recurrent malignant ascites: a NICE Medical Technology Guidance
    Judith White
    CEDAR, Cardiff and Vale University Health Board, Cardiff, Wales, UK
    Appl Health Econ Health Policy 10:299-308. 2012
  8. pmc Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage
    Susan N Thomas
    Institute of Bioengineering, School of Life Sciences, Swiss Federal Institute of Technology, Lausanne EPFL, 1015 Lausanne, Switzerland
    J Immunol 189:2181-90. 2012
  9. ncbi Bacterial meningitis caused by the use of ventricular or lumbar cerebrospinal fluid catheters
    Rogier P Schade
    Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands
    J Neurosurg 102:229-34. 2005
  10. ncbi Prenatal bladder drainage in the management of fetal lower urinary tract obstruction: a systematic review and meta-analysis
    T Justin Clark
    Division of Reproductive and Child Health, Birmingham Women s Hospital, University of Birmingham, Birmingham, United Kingdom
    Obstet Gynecol 102:367-82. 2003

Detail Information

Publications457 found, 100 shown here

  1. doi Unilateral versus bilateral endoscopic metal stenting for malignant hilar biliary obstruction
    Itaru Naitoh
    Department of Gastroenterology and Metabolism, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan
    J Gastroenterol Hepatol 24:552-7. 2009
    The extent of liver drainage for palliative treatment of malignant hilar biliary obstruction is controversial...
  2. pmc Intra-abdominal pressure alterations after large pancreatic pseudocyst transcutaneous drainage
    Theodossis S Papavramidis
    1st Propedeutic Department of Surgery, AHEPA University Hospital, Aristotle s University of Thessaloniki, Macedonia, Greece
    BMC Gastroenterol 9:42. 2009
    ..Aims of the present study were to evaluate the intra-abdominal pressure (IAP) induced by large pancreatic pseudocysts and to examine the effect of their transcutaneous drainage on IAP.
  3. doi Endoscopic ultrasound-guided versus conventional transmural drainage for pancreatic pseudocysts: a prospective randomized trial
    D H Park
    Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Songpa Gu, 138 736, Seoul, South Korea
    Endoscopy 41:842-8. 2009
    Although endoscopic ultrasound (EUS)-guided transmural drainage (EUD) is preferred over conventional transmural drainage (CTD) of pancreatic pseudocysts by endoscopy in many centers, its superiority with respect to technical success and ..
  4. ncbi Seroma following breast cancer surgery
    C J Pogson
    Breast Unit, Mayday University Hospital, London Road, Croydon CR7 7YE, UK
    Eur J Surg Oncol 29:711-7. 2003
    ..Seroma is a common problem following breast cancer surgery causing patient discomfort and prolongation of hospital stay...
  5. ncbi The addition of manual lymph drainage to compression therapy for breast cancer related lymphedema: a randomized controlled trial
    Margaret L McNeely
    Department of Rehabilitation Medicine, Cross Cancer Institute, Edmonton, Alberta, Canada
    Breast Cancer Res Treat 86:95-106. 2004
    The purpose of this investigation was to compare the reduction in arm lymphedema volume achieved from manual lymph drainage massage (MLD) in combination with multi-layered compression bandaging (CB) to that achieved by CB alone.
  6. doi A step-up approach or open necrosectomy for necrotizing pancreatitis
    Hjalmar C van Santvoort
    University Medical Center, Utrecht, The Netherlands
    N Engl J Med 362:1491-502. 2010
    ..Necrotizing pancreatitis with infected necrotic tissue is associated with a high rate of complications and death. Standard treatment is open necrosectomy. The outcome may be improved by a minimally invasive step-up approach...
  7. doi PleurX peritoneal catheter drainage system for vacuum-assisted drainage of treatment-resistant, recurrent malignant ascites: a NICE Medical Technology Guidance
    Judith White
    CEDAR, Cardiff and Vale University Health Board, Cardiff, Wales, UK
    Appl Health Econ Health Policy 10:299-308. 2012
    The PleurX peritoneal drainage catheter for drainage of malignant ascites in a community setting has been evaluated by the NICE Medical Technologies Evaluation Programme...
  8. pmc Impaired humoral immunity and tolerance in K14-VEGFR-3-Ig mice that lack dermal lymphatic drainage
    Susan N Thomas
    Institute of Bioengineering, School of Life Sciences, Swiss Federal Institute of Technology, Lausanne EPFL, 1015 Lausanne, Switzerland
    J Immunol 189:2181-90. 2012
    ..Ag, and immune cells from peripheral tissues to lymph nodes (LNs), yet the contribution of peripheral lymphatic drainage to adaptive immunity remains poorly understood...
  9. ncbi Bacterial meningitis caused by the use of ventricular or lumbar cerebrospinal fluid catheters
    Rogier P Schade
    Department of Medical Microbiology, Leiden University Medical Center, Leiden, The Netherlands
    J Neurosurg 102:229-34. 2005
    In the present study the authors compared the incidence and risk factors for external drainage-related bacterial meningitis (ED-BM) by using ventricular and lumbar catheters.
  10. ncbi Prenatal bladder drainage in the management of fetal lower urinary tract obstruction: a systematic review and meta-analysis
    T Justin Clark
    Division of Reproductive and Child Health, Birmingham Women s Hospital, University of Birmingham, Birmingham, United Kingdom
    Obstet Gynecol 102:367-82. 2003
    To estimate the effect of prenatal bladder drainage on perinatal survival in fetuses with lower urinary tract obstruction.
  11. doi Accuracy of external ventricular drainage catheter placement
    Mohammad Ghazi Abdoh
    Department of Neurosurgery, University Paris East, Medical School, Assitance Publique Hôpitaux de Paris, Henri Mondor Hospital, Creteil, France
    Acta Neurochir (Wien) 154:153-9. 2012
    External ventricular drainage (EVD) is a freehand neurosurgical procedure performed routinely using the anatomical landmarks.
  12. ncbi Effect of pyloric drainage procedures on gastric passage and bile reflux after esophagectomy with gastric conduit reconstruction
    Daniel Palmes
    Department of General Surgery, Munster University Hospital, Waldeyerstr 1, 48149, Munster, Germany
    Langenbecks Arch Surg 392:135-41. 2007
    Controversy still exists about the need for pyloric drainage procedures (pyloroplasty or pyloromyotomy) after esophagectomy with esophagogastrostomy and vagotomy...
  13. doi Transenteric drainage of pancreatic-fluid collections with fully covered self-expanding metallic stents (with video)
    Jayant P Talreja
    Digestive Health Center of Excellence, University of Virginia Health System, Charlottesville, Virginia 22908 0708, USA
    Gastrointest Endosc 68:1199-203. 2008
    b>Drainage of pancreatic-fluid collections (PFCs) by using fully covered self-expanding metallic stents (CSEMSs) offers the option of providing a larger-diameter access fistula for drainage when compared with plastic stents.
  14. ncbi Marked reduction of cerebral vasospasm with lumbar drainage of cerebrospinal fluid after subarachnoid hemorrhage
    Paul Klimo
    Department of Neurosurgery, University of Utah, Salt Lake City, Utah 84132 2303, USA
    J Neurosurg 100:215-24. 2004
    ..The authors hypothesize that lumbar cisternal drainage can remove blood from the basal subarachnoid spaces more effectively than an external ventricular drain (EVD)...
  15. doi Effect of treatment with low-intensity and extremely low-frequency electrostatic fields (Deep Oscillation) on breast tissue and pain in patients with secondary breast lymphoedema
    Silke Jahr
    Department of Physical Medicine and Rehabilitation, Charité Universitetsmedizin Berlin, Germany
    J Rehabil Med 40:645-50. 2008
    ..lymphoedema of the breast following surgical treatment and to assess the therapeutic benefit of treatment with low-intensity and extremely low-frequency electrostatic fields (Deep Oscillation), supplementing manual lymphatic drainage.
  16. doi Laparoscopic drainage of pancreatic pseudocysts: a methodological approach
    Numan Hamza
    The Manchester Hepato Pancreato Biliary Centre, North Manchester General Hospital, Delaunays Road, Crumpsall, Manchester M8 5RB, UK
    J Gastrointest Surg 14:148-55. 2010
    This paper describes our tailored and methodological approach to laparoscopic drainage of pancreatic pseudocysts (PPs) based on an anatomical classification.
  17. doi Parapneumonic pleural effusion and empyema
    Coenraad F N Koegelenberg
    Division of Pulmonology, Department of Medicine, University of Stellenbosch and Tygerberg Academic Hospital, Cape Town, South Africa
    Respiration 75:241-50. 2008
    ..20, glucose <3.4 mmol/l (60 mg/dl) or positive microbial stain and/or culture. Drainage is most frequently achieved with tube thoracostomy...
  18. doi Combined duodenal stent placement and endoscopic ultrasonography-guided biliary drainage for malignant duodenal obstruction with biliary stricture
    Masaya Iwamuro
    Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama, Japan
    Dig Endosc 22:236-40. 2010
    ..technique for combined endoscopic duodenal stent placement and endoscopic ultrasonography (EUS)-guided biliary drainage. Between May 2007 and September 2009, this combined technique was performed on seven patients with distal biliary ..
  19. doi Frequency of complications during EUS-guided drainage of pancreatic fluid collections in 148 consecutive patients
    Shyam Varadarajulu
    Department of Medicine, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA
    J Gastroenterol Hepatol 26:1504-8. 2011
    The aim of the present study was to evaluate the frequency of complications during endoscopic ultrasound (EUS)-guided drainage of pancreatic fluid collections (PFC), identify contributing factors, and report on management outcomes.
  20. doi Fine needle aspiration using forward-viewing endoscopic ultrasonography
    M Kida
    Department of Gastroenterology, Kitasato University East Hospital, 2 1 1 Asamizodai, Sagamihara, Kanagawa, Japan
    Endoscopy 43:796-801. 2011
    ..We had the opportunity to use this forward-viewing echo endoscope and to study its clinical usefulness, mainly for diagnostic EUS-FNA...
  21. doi Clinical evaluation of a novel lumen-apposing metal stent for endosonography-guided pancreatic pseudocyst and gallbladder drainage (with videos)
    Takao Itoi
    Department of Gastroenterology and Hepatology, Tokyo Medical University, Tokyo, Japan
    Gastrointest Endosc 75:870-6. 2012
    Tubular plastic and metal stents have inherent shortcomings when used for transenteric drainage of fluid collections.
  22. doi NOTES(®) stapled cystgastrostomy: a novel approach for surgical management of pancreatic pseudocysts
    Ratnakishore Pallapothu
    Department of Surgery and Medicine, Tufts University School of Medicine, Springfield, MA 01199, USA
    Surg Endosc 25:883-9. 2011
    Traditional approach for surgical management of mature pancreatic pseudocysts is by internal surgical drainage. Endoscopic drainage procedures have also been described...
  23. doi Percutaneous hepatic abscess drainage: do multiple abscesses or multiloculated abscesses preclude drainage or affect outcome?
    Chang Hsien Liu
    Department of Radiology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit Street, Boston, MA 02114, USA
    J Vasc Interv Radiol 20:1059-65. 2009
    To compare the effectiveness of percutaneous abscess drainage in patients with pyogenic liver abscesses of the following types: single, single multiloculated, multiple, and multiple multiloculated.
  24. doi Preoperative biliary drainage in patients with obstructive jaundice: history and current status
    N A van der Gaag
    Department of Surgery, Academic Medical Center at the University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    J Gastrointest Surg 13:814-20. 2009
    Preoperative biliary drainage (PBD) has been introduced to improve outcome after surgery in patients suffering from obstructive jaundice due to a potentially resectable proximal or distal bile duct/pancreatic head lesion...
  25. doi EUS-guided hepaticogastrostomy with a fully covered metal stent as the biliary diversion technique for an occluded biliary metal stent after a failed ERCP (with videos)
    Do Hyun Park
    Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea
    Gastrointest Endosc 71:413-9. 2010
    Percutaneous transhepatic biliary drainage (PTBD) may be the last resort for an occluded biliary metal stent when the ERCP was unsuccessful.
  26. ncbi Endoscopic-ultrasound-guided endoscopic transmural drainage of pancreatic pseudocysts and abscesses
    Cesar Vivian Lopes
    Endoscopy Unit, Paoli Calmettes Institute, 232 Boulevard St Marguerite, 13273 Marseille Cedex 9, France
    Scand J Gastroenterol 42:524-9. 2007
    ..Minimally invasive approaches have been encouraged. The aim of this study was to evaluate the results of the endoscopic-ultrasound-guided (EUS) endoscopic transmural drainage of these pancreatic collections.
  27. ncbi Randomized clinical trial investigating the use of drains and fibrin sealant following surgery for breast cancer
    P K Jain
    Department of Surgery, Scarborough General Hospital, Woodland Drive, Scarborough YO12 6QL, UK
    Br J Surg 91:54-60. 2004
    Despite limited evidence, closed suction drainage is often used to reduce the risk of seroma formation after breast cancer surgery...
  28. ncbi A prospective comparison of clamping the drain or post-operative salvage of blood in reducing blood loss after total knee arthroplasty
    N Tsumara
    Hyogo Rehabilitation Center, 1070 Akebono cho Nishi ku, Kobe 651 2181, Japan
    J Bone Joint Surg Br 88:49-53. 2006
    ..Drain clamping with intra-articular injection of saline with adrenaline is more effective than post-operative autologous blood transfusion in reducing blood loss during total knee arthroplasty...
  29. ncbi A randomized controlled crossover study of manual lymphatic drainage therapy in women with breast cancer-related lymphoedema
    A F Williams
    Marie Curie Centre, Fairmile, Frogston Road West, Edinburgh, UK
    Eur J Cancer Care (Engl) 11:254-61. 2002
    This paper describes a randomized controlled crossover study examining the effects of manual lymphatic drainage (MLD) in 31 women with breast cancer-related lymphoedema...
  30. ncbi Use of fibrin sealant to reduce bloody drainage and hemoglobin loss after total knee arthroplasty: a brief note on a randomized prospective trial
    G J Wang
    University of Virginia Health System, Charlottesville 22908, USA
    J Bone Joint Surg Am 83:1503-5. 2001
    ..A phase-III trial that included fifty-three patients undergoing unilateral primary total knee arthroplasty with cement was conducted to investigate the hemostatic efficacy of fibrin sealant...
  31. doi Endosonography-guided biliary drainage in cases with difficult transpapillary endoscopic biliary drainage
    Jun Horaguchi
    Department of Gastroenterology, Sendai City Medical Center, Miyagino ku, Sendai, Japan
    Dig Endosc 21:239-44. 2009
    Recently, reports on a new endoscopic biliary drainage technique utilizing endosonographic guidance (endosonography-guided biliary drainage [ESBD]) have been increasing...
  32. pmc External drainage of pancreatic duct with a stent to reduce leakage rate of pancreaticojejunostomy after pancreaticoduodenectomy: a prospective randomized trial
    Ronnie T P Poon
    Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
    Ann Surg 246:425-33; discussion 433-5. 2007
    Pancreatic fistula is a leading cause of morbidity and mortality after pancreaticoduodenectomy. External drainage of pancreatic duct with a stent has been shown to reduce pancreatic fistula rate of pancreaticojejunostomy in a few ..
  33. ncbi Transgastric endoscopic ultrasonography-guided biliary drainage: results of a pilot study
    E Bories
    Endoscopic Unit, Paoli Calmettes Institute, Marseille, France
    Endoscopy 39:287-91. 2007
    ..We present our first results with an alternative technique: endoscopic ultrasonography (EUS)-guided transgastric biliary drainage.
  34. doi Preoperative biliary drainage for cancer of the head of the pancreas
    Niels A van der Gaag
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    N Engl J Med 362:129-37. 2010
    The benefits of preoperative biliary drainage, which was introduced to improve the postoperative outcome in patients with obstructive jaundice caused by a tumor of the pancreatic head, are unclear.
  35. ncbi Selective MRCP and CT-targeted drainage of malignant hilar biliary obstruction with self-expanding metallic stents
    Martin L Freeman
    Division of Gastroenterology, Hennepin County Medical Center, Minneapolis, Minnesota 55415, USA
    Gastrointest Endosc 58:41-9. 2003
    ..of malignant hilar biliary obstruction is controversial with respect to optimal types of stents and extent of drainage. This study evaluated outcomes of selective MRCP and CT-targeted drainage with self-expanding metallic stents.
  36. doi Y-shaped endoscopic bilateral metal stent placement for malignant hilar biliary obstruction: prospective long-term study
    Jae Chul Hwang
    Department of Gastroenterology, Ajou University School of Medicine, San 5, Woncheon dong, Yongtong Gu, Suwon, Republic of Korea
    Scand J Gastroenterol 46:326-32. 2011
    Although still controversial, bilateral stenting may be the best option for palliative drainage of malignant hilar biliary obstruction...
  37. ncbi Endoscopic bilateral metal stent placement for advanced hilar cholangiocarcinoma: a pilot study of a newly designed Y stent
    Jung Hyun Lee
    Department of Internal Medicine, Pusan National University College of Medicine, Seo Gu, Busan, Korea
    Gastrointest Endosc 66:364-9. 2007
    ....
  38. ncbi Chronic subdural haematoma: surgical treatment and outcome in 1000 cases
    Miguel Gelabert-Gonzalez
    Neurosurgical Service, Department of Surgery, Clinic Hospital of Santiago, University of Santiago de Compostela, La Choupana, 15706 Santiago de Compostela, Spain
    Clin Neurol Neurosurg 107:223-9. 2005
    ..of 1000 patients harbouring 1097 chronic subdural haematoma treated with burr-hole craniotomy with closed-system drainage was carried out. The series included 628 males and 372 females, age range 12-100 years, mean age 72.7+/-11...
  39. doi EUS-guided biliary drainage: a case series
    I Tarantino
    Department of Gastroenterology, ISMETT UPMC, Palermo, Italy
    Endoscopy 40:336-9. 2008
  40. pmc An appraisal of surgical and percutaneous drainage for pyogenic liver abscesses larger than 5 cm
    Yu Meng Tan
    From the Department of Surgery, Singapore General Hospital Department of Surgical Oncology, National Cancer Center, Singapore
    Ann Surg 241:485-90. 2005
    To determine whether first-line treatment with percutaneous or surgical drainage of liver abscesses larger than 5 cm results in better clinical outcome.
  41. pmc Pre-operative biliary drainage for obstructive jaundice
    Yuan Fang
    Department of Neurosurgery, West China Hospital, Sichuan University, Chengdu, China
    Cochrane Database Syst Rev 9:CD005444. 2012
    ..There is considerable controversy as to whether temporary relief of biliary obstruction prior to major definitive surgery (pre-operative biliary drainage) is of any benefit to the patient.
  42. ncbi Treatment options for hepatic cystic echinococcosis
    Raymond A Smego
    Department of Medicine, The University of North Dakota, School of Medicine and Health Sciences, Fargo, ND, USA
    Int J Infect Dis 9:69-76. 2005
    ..granulosis has made it possible to undertake ultrasound- or computed tomography-guided transhepatic percutaneous drainage (termed puncture, aspiration, injection, and re-aspiration (PAIR)) of hydatid cysts...
  43. doi Do drainage liquid characteristics serve as predictors for seroma formation after incisional hernia repair?
    C D Klink
    Department of Surgery, RWTH Aachen University Hospital, Pauwelsstr 30, 52074, Aachen, Germany
    Hernia 14:175-9. 2010
    ..The aim of this study was to determine the characteristics of drainage liquid as a potential predictor for the development of seroma after incisional hernia mesh repair...
  44. pmc Manual lymphatic drainage therapy in patients with breast cancer related lymphoedema
    Marta López Martín
    Unidad de Investigacion, Hospital Universitario de la Princesa, Diego de León 36, 28046 Madrid, Spain
    BMC Cancer 11:94. 2011
    ..The aim of this study is to analyze the effectiveness of Manual Lymphatic Drainage in the treatment of postmastectomy lymphoedema in order to reduce the volume of lymphoedema and evaluate the ..
  45. ncbi Long-term results of single-session percutaneous drainage and ethanol sclerotherapy in simple renal cysts
    Devrim Akinci
    Department of Radiology, School of Medicine, Hacettepe University, Shhiye, Ankara TR 06100, Turkey
    Eur J Radiol 54:298-302. 2005
    ..To demonstrate the efficacy and long-term results of the single-session ethanol sclerotherapy in simple renal cysts...
  46. doi External ventricular and lumbar drainage-associated meningoventriculitis: prospective analysis of time-dependent infection rates and risk factor analysis
    S Scheithauer
    Department of Infection Control and Infectious Diseases, University Hospital, RWTH Aachen, Pauwelsstrasse 30, 52074, Aachen, Germany
    Infection 38:205-9. 2010
    Data on time-dependency of external ventricular drainage (EVD)- and lumbar drainage (LD)-associated meningoventriculitis (MV) are scarce and discussions on the subject are controversial; no data exist for infection rates (IR) relative to ..
  47. doi Subglottic secretion drainage for preventing ventilator-associated pneumonia: an updated meta-analysis of randomized controlled trials
    Fei Wang
    Department of Anesthesiology, Changhai Hospital, Second Military Medical University, Shanghai, China
    J Trauma Acute Care Surg 72:1276-85. 2012
    Subglottic secretion drainage (SSD) has been shown to be associated with a lower incidence of ventilator-associated pneumonia (VAP) in a previous meta-analysis...
  48. doi Use of a transanal drainage tube for prevention of anastomotic leakage and bleeding after anterior resection for rectal cancer
    Wen Tao Zhao
    Department of Colorectal Surgery, The First Affiliated Hospital, Guangzhou University of Traditional Chinese Medicine, Guangzhou, People s Republic of China
    World J Surg 37:227-32. 2013
    The aim of the present study was to investigate the usefulness of the transanal drainage tube for prevention of anastomotic leakage and bleeding after anterior resection for rectal cancer.
  49. ncbi Randomized multicenter trial of sentinel node biopsy versus standard axillary treatment in operable breast cancer: the ALMANAC Trial
    Robert E Mansel
    Department of Surgery, Cardiff University, Cardiff, UK
    J Natl Cancer Inst 98:599-609. 2006
    ....
  50. doi A comparative study of the patients with bilateral or unilateral chronic subdural hematoma: precipitating factors and postoperative outcomes
    Tai Hsin Tsai
    Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    J Trauma 68:571-5. 2010
    ..The purpose of this study was to compare the clinical presentations, precipitating factors, computed tomography (CT) scan findings, postoperative complications, and outcomes between patients with bilateral and unilateral CSDH...
  51. ncbi The expression levels of plasma membrane transporters in the cholestatic liver of patients undergoing biliary drainage and their association with the impairment of biliary secretory function
    J Shoda
    Department of Gastroenterology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki, Japan
    Am J Gastroenterol 96:3368-78. 2001
    OBJECTIVES: Percutaneous transhepatic biliary drainage (PTBD) has been believed to reduce hyperbilirubinemia in patients with obstructive cholestasis and to lessen liver injury through bile acid retention...
  52. doi Newly designed large cell Niti-S stent for malignant hilar biliary obstruction: a pilot study
    Hirofumi Kogure
    Department of Gastroenterology, Faculty of Medicine, University of Tokyo, 7 3 1 Hongo, Bunkyo ku, Tokyo, 113 8655, Japan
    Surg Endosc 25:463-7. 2011
    Whether uni- or bilateral drainage should be performed for malignant hilar biliary obstruction remains a matter of debate. Moreover, endoscopic placement of bilateral metallic stents has been considered difficult and complicated...
  53. ncbi Laparotomy versus peritoneal drainage for necrotizing enterocolitis or isolated intestinal perforation in extremely low birth weight infants: outcomes through 18 months adjusted age
    Martin L Blakely
    University of Tennessee Health Science Center, Memphis, Tennessee, USA
    Pediatrics 117:e680-7. 2006
    ....
  54. ncbi Percutaneous placement of biliary metallic stents in patients with malignant hilar obstruction: unilobar versus bilobar drainage
    Mehmet Inal
    Department of Radiology, Cukurova University Faculty of Medicine, 01330 Balcali, Adana, Turkey
    J Vasc Interv Radiol 14:1409-16. 2003
    ..To evaluate the necessity of draining more than one hepatic duct in malignant hilar obstructions...
  55. doi Standardized pelvic drainage of anastomotic leaks following anterior resection without diversional stomas
    Junjie Peng
    Department of Colorectal Surgery, Cancer Hospital of Fudan University, Shanghai, China
    Am J Surg 199:753-8. 2010
    ..Anastomotic leakage is a serious complication in rectal cancer surgery. More than one third of rectal cancer patients with low anterior resection (LAR) will receive defunctional stomas during primary operation...
  56. doi Bilateral biliary drainage for malignant hilar obstruction using the 'stent-in-stent' method with a Y-stent: efficacy and complications
    Dong Uk Kim
    Departments of Internal Medicine, Pusan National University Hospital, Busan, South Korea
    Eur J Gastroenterol Hepatol 25:99-106. 2013
    ..The usefulness of bilateral stent placement for malignant hilar obstruction is still under debate. Nevertheless, many endoscopists advocate the placement of an endoscopic bilateral metal stent using various new devices and techniques...
  57. doi Early versus late drain removal after standard pancreatic resections: results of a prospective randomized trial
    Claudio Bassi
    Department of Surgery, G B Rossi Hospital, University of Verona, Verona, Italy
    Ann Surg 252:207-14. 2010
    ..The role of surgically placed intra-abdominal drainages after pancreatic resections has not been clearly established. In particular, their effect on morbidity rates and the optimal timing for their removal remains controversial...
  58. doi EUS-guided biliary drainage with placement of a new partially covered biliary stent for palliation of malignant biliary obstruction: a case series
    C Fabbri
    Unit of Gastroenterology and Digestive Endoscopy, AUSL Bologna Bellaria Maggiore Hospital, Largo Nigrisoli 2, Bologna, Italy
    Endoscopy 43:438-41. 2011
    Endoscopic ultrasonography-guided biliary drainage (EUS-BD) has been developed as an alternative drainage technique in patients with obstructive jaundice where endoscopic retrograde cholangiopancreatography (ERCP) has failed...
  59. doi Prevention of biliary complication in radiofrequency ablation for hepatocellular carcinoma-Cooling effect by endoscopic nasobiliary drainage tube
    Tsuneyoshi Ogawa
    Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2 5 1 Shikata cho, Okayama 700 8558, Japan
    Eur J Radiol 73:385-90. 2010
    ..Therefore, it may require interventional drainage for decompression during the follow-up period...
  60. doi Comparison of pancreas-transplanted type 1 diabetic patients with portal-venous versus systemic-venous graft drainage: impact on glucose regulatory hormones and the growth hormone/insulin-like growth factor-I axis
    Jan Frystyk
    Medical Research Laboratories, Aarhus University Hospital, Nørrebrogade 44, Aarhus C, Denmark
    J Clin Endocrinol Metab 93:1758-66. 2008
    Pancreas grafts can be drained through the iliac vein (systemic drainage) or the portal vein.
  61. doi Occurrence and role of algae and fungi in acid mine drainage environment with special reference to metals and sulfate immobilization
    Bidus Kanti Das
    Department of Mining Engineering, Indian Institute of Technology Kharagpur, Kharagpur 721302, India
    Water Res 43:883-94. 2009
    Passive remediation of Acid Mine Drainage (AMD) is a popular technology under development in current research...
  62. doi EUS-guided pancreatic pseudocyst drainage: simultaneous placement of stents and nasocystic catheter using double-guidewire technique
    Takao Itoi
    Department of Gastroenterology and Hepatology, Tokyo Medical University, Japan
    Dig Endosc 21:S53-6. 2009
    Endoscopic ultrasonography (EUS)-guided pancreatic pseudocyst drainage has become the standard and safety procedure in many centers for nonsurgical treatment...
  63. ncbi EUS-guided transduodenal biliary drainage in unresectable pancreatic cancer with obstructive jaundice
    Tiing Leong Ang
    Division of Gastroenterology, Department of Medicine, Changi General Hospital, Singapore, Singapore
    JOP 8:438-43. 2007
    Endoscopic transpapillary biliary drainage is the procedure of choice for biliary decompression in patients with unresectable pancreatic cancer...
  64. doi Endoscopic ultrasound-guided transduodenal placement of a fully covered metal stent for palliative biliary drainage in patients with malignant biliary obstruction
    Ali A Siddiqui
    Department of Internal Medicine, Dallas Veterans Affairs Medical Center, 4500 S Lancaster Road 111B1, Dallas, TX 75216, USA
    Surg Endosc 25:549-55. 2011
    Endoscopic ultrasound (EUS)-guided biliary drainage (EUSBD) has been described as a viable alternative to percutaneous transhepatic cholangiography (PTC) in patients in whom ERCP has been unsuccessful...
  65. doi Temporary cystogastrostomy with self-expanding metallic stents for pancreatic necrosis
    S Belle
    Department of Medicine II, Medical Faculty Mannheim, University of Heidelberg, Mannheim, Germany
    Endoscopy 42:493-5. 2010
    Conventional endoscopic drainage of symptomatic pancreatic pseudocysts has its limitations when the content of the collection is nonfluid...
  66. ncbi Endoscopic ultrasound-guided bilioduodenal anastomosis: a new technique for biliary drainage
    M Giovannini
    Endoscopy Unit, Paoli Calmettes Institute, Marseilles, France
    Endoscopy 33:898-900. 2001
    ..We present a new technique of biliary drainage using endoscopic ultrasound (EUS) and EUS-guided puncture of the common bile duct (CBD)...
  67. doi Graded dilation technique for EUS-guided drainage of peripancreatic fluid collections: an assessment of outcomes and complications and technical proficiency (with video)
    Shyam Varadarajulu
    Division of Gastroenterology Hepatology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294, USA
    Gastrointest Endosc 68:656-66. 2008
    Although the utility and safety of EUS and EUS-guided FNA is well known, there is a need for more data on outcomes and complications of EUS-guided drainage procedures.
  68. pmc EUS-guided drainage is more successful in pancreatic pseudocysts compared with abscesses
    Riadh Sadik
    Institute of Medicine, Department of Internal Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
    World J Gastroenterol 17:499-505. 2011
    To compare the results for endoscopic ultrasound (EUS)-guided drainage of clear fluid pancreatic pseudocysts with the results for abscess drainage.
  69. pmc Assessment of lymphatic contractile function after manual lymphatic drainage using near-infrared fluorescence imaging
    I Chih Tan
    Center for Molecular Imaging, The Brown Foundation Institute of Molecular Medicine, The University of Texas Health Science Center, Houston, TX, USA
    Arch Phys Med Rehabil 92:756-764.e1. 2011
    To investigate the feasibility of assessing the efficacy of manual lymphatic drainage (MLD), a method for lymphedema (LE) management, by using near-infrared (NIR) fluorescence imaging.
  70. doi Crisscross-configured dual stent placement for trisectoral drainage in patients with advanced biliary hilar malignancies
    Jae Ik Bae
    Department of Radiology, Ajou University School of Medicine, Suwon, Republic of Korea
    J Vasc Interv Radiol 19:1614-9. 2008
    ..To evaluate technical success and clinical efficacy of crisscross-configured dual biliary stent implantation in patients with a biliary hilar tumor extending beyond the segmental ducts...
  71. doi Endoscopic ultrasound-guided biliodigestive drainage is a good alternative in patients with unresectable cancer
    M A Ramírez-Luna
    Endoscopy Department, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
    Endoscopy 43:826-30. 2011
    A total of 11 prospective cases of endoscopic ultrasound (EUS)-guided cholangio-drainage (EUCD) in patients with end-stage biliopancreatic cancer and biliary tract obstruction are reported...
  72. doi Endoscopic ultrasound-guided choledochoduodenostomy for palliative biliary drainage in cases with inoperable pancreas head carcinoma
    Keiji Hanada
    Center for Gastroendoscopy, Onomichi General Hospital, Japan
    Dig Endosc 21:S75-8. 2009
    Endoscopic transpapillary biliary drainage (EBD) or stenting is the gold standard treatment for inoperable malignant biliary obstruction...
  73. doi EUS-guided biliary drainage with transluminal stenting after failed ERCP: predictors of adverse events and long-term results
    Do Hyun Park
    Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea
    Gastrointest Endosc 74:1276-84. 2011
    EUS-guided biliary drainage (EUS-BD) has been proposed as an effective alternative for percutaneous transhepatic biliary drainage (PTBD) after failed ERCP...
  74. doi Number of burr holes as independent predictor of postoperative recurrence in chronic subdural haematoma
    P Taussky
    Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland
    Br J Neurosurg 22:279-82. 2008
    ..All patients underwent irrigation and placement of closed-system drainage. Out of the 97 haematoma, 63 (65%) haematomas were treated with two burr holes, whereas 34 (35%) were treated ..
  75. ncbi HHV-8/KSHV-negative and CD20-positive primary effusion lymphoma successfully treated by pleural drainage followed by chemotherapy containing rituximab
    Yasushi Terasaki
    Division of Internal Medicine, Toyama City Hospital, Toyama
    Intern Med 47:2175-8. 2008
    ..After pleural drainage, malignant cells disappeared spontaneously in a small amount of the remaining pleural effusion without ..
  76. doi Role of controlled lumbar CSF drainage for ICP control in aneurysmal SAH
    Ali Murad
    Department of Neurosurgery, Loma Linda University Medical Center, 11234 Anderson Street, Rm 2562 B, Loma Linda, CA 92354, USA
    Acta Neurochir Suppl 110:183-7. 2011
    a prospective study of lumbar CSF drainage in the setting of raised intra-cranial pressure refractory to medical management and ventriculostomy placement is presented...
  77. doi Evaluation of the clinical effectiveness of physiotherapeutic management of lymphoedema in palliative care patients
    Katri Elina Clemens
    Department of Science and Research, Centre for Palliative Medicine, University of Bonn, Bonn, Germany
    Jpn J Clin Oncol 40:1068-72. 2010
    Lymphoedema is a common sequela of cancer or its treatment that affects lymph node drainage. The physiotherapist, as member of the multiprofessional team in palliative care, is one of the keys to successful rehabilitation and management ..
  78. ncbi Relationship between drainage catheter location and postoperative recurrence of chronic subdural hematoma after burr-hole irrigation and closed-system drainage
    H Nakaguchi
    Department of Neurosurgery, Tokyo Kosei Nenkin Hospital, Tokyo, Japan
    J Neurosurg 93:791-5. 2000
    This study was conducted to determine the best position for the subdural drainage catheter to achieve a low recurrence rate after burr-hole irrigation and closed-system drainage of chronic subdural hematoma (CSDH).
  79. doi Chronic subdural hematomas treated by burr hole trepanation and a subperiostal drainage system
    Daniel Zumofen
    Department of Neurosurgery, Centre Hospitalier Universitaire Vaudois, University of Lausanne, Lausanne, Switzerland
    Neurosurgery 64:1116-21; discussion 1121-2. 2009
    Most symptomatic chronic subdural hematomas are treated by subdural drainage. However, a subperiostal (i.e., extracranial) passive closed-drainage system in combination with double burr hole trepanation is used at our institution...
  80. doi Long-term follow-up of percutaneous transhepatic biliary drainage (PTBD) in patients with benign bilioenterostomy stricture
    A Weber
    Department of Internal Medicine II, Technical University of Munich, Germany
    Endoscopy 41:323-8. 2009
    ..Hence, percutaneous transhepatic biliary drainage (PTBD) has become the treatment of choice for the management of these patients...
  81. ncbi Treatment of biliary obstruction in selected patients by endoscopic ultrasonography (EUS)-guided transluminal biliary drainage
    U Will
    Department of Internal Medicine III, Municipal Hospital, Gera, Germany
    Endoscopy 39:292-5. 2007
    ..reconstruction), the alternative treatment is considered to be percutaneous transhepatic cholangiography and drainage (PTCD)...
  82. pmc Prosthesis for open pleurostomy (POP): management for chronic empyemas
    Luiz Tarcísio Brito Filomeno
    Department of Thoracic Surgery, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo SP, Brazil
    Clinics (Sao Paulo) 64:203-8. 2009
    ..Herein, we report our 13-year experience with this device in the management of different kinds of pleural empyema...
  83. ncbi Choroidal drainage in the management of acute angle closure after topiramate toxicity
    Rajul Parikh
    L V Prasad Eye Institute, Hyderabad, Andhra Pradesh, India
    J Glaucoma 16:691-3. 2007
    To report the role of choroidal drainage in patient with acute bilateral angle closure secondary to cilio-choroidal effusion with Topiramate.
  84. doi Initial experience with the prototype forward-viewing echoendoscope for therapeutic interventions other than pancreatic pseudocyst drainage (with videos)
    Jessica M Trevino
    Division of Gastroenterology Hepatology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama 35294, USA
    Gastrointest Endosc 69:361-5. 2009
    ..In an effort to overcome this limitation, a prototype forward-viewing echoendoscope was developed and successfully tested for performing transgastric drainage of pancreatic pseudocysts.
  85. doi Prospective randomized trial comparing EUS and EGD for transmural drainage of pancreatic pseudocysts (with videos)
    Shyam Varadarajulu
    Division of Gastroenterology Hepatology, University of Alabama at Birmingham School of Medicine, Birmingham, Alabama, USA
    Gastrointest Endosc 68:1102-11. 2008
    Although prior studies evaluated the role of EUS and EGD for drainage of pancreatic pseudocysts, there are no randomized trials that compared the technical outcomes between both modalities.
  86. pmc Peroral endoscopic drainage/debridement of walled-off pancreatic necrosis
    Georgios I Papachristou
    Division of Gastroenterology and Hepatology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Ann Surg 245:943-51. 2007
    Experience with minimal access, transoral/transmural endoscopic drainage/debridement of walled-off pancreatic necrosis (WOPN) after necrotizing pancreatitis is limited. We sought to determine outcome using this technique.
  87. doi EUS-guided biliary drainage with one-step placement of a fully covered metal stent for malignant biliary obstruction: a prospective feasibility study
    Do Hyun Park
    Division of Gastroenterology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul 138 736, South Korea
    Am J Gastroenterol 104:2168-74. 2009
    Endoscopic ultrasound (EUS)-guided biliary drainage (EUSBD) with plastic stents has been introduced as an alternative to percutaneous transhepatic biliary drainage (PTBD) in cases of biliary obstruction when endoscopic retrograde ..
  88. doi Endoscopic ultrasound guided biliary drainage in patients with unapproachable ampullae due to malignant duodenal obstruction
    Paul J Belletrutti
    Gastroenterology and Nutrition Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, P O Box 273, New York, NY 10065, USA
    J Gastrointest Cancer 42:137-42. 2011
    ..cholangiopancreatography (ERCP) is not possible due to duodenal obstruction, endoscopic ultrasound-guided biliary drainage (EUS-BD) has emerged as an alternate mode of biliary decompression...
  89. doi Percutaneous transhepatic biliary drainage catheter tract recurrence in cholangiocarcinoma
    Y Takahashi
    Division of Surgical Oncology, Department of Surgery, Nagoya University Graduate School of Medicine, Nagoya, Japan
    Br J Surg 97:1860-6. 2010
    The aim of the study was to clarify the incidence, risk factors and treatment of percutaneous transhepatic biliary drainage (PTBD) catheter tract recurrence in patients with resected cholangiocarcinoma.
  90. doi Long-term outcomes of endoscopic vs surgical drainage of the pancreatic duct in patients with chronic pancreatitis
    Djuna L Cahen
    Department of Gastroenterology and Hepatology, Erasmus Medical Center, Rotterdam, The Netherlands
    Gastroenterology 141:1690-5. 2011
    A randomized trial that compared endoscopic and surgical drainage of the pancreatic duct in patients with advanced chronic pancreatitis reported a significant benefit of surgery after a 2-year follow-up period...
  91. doi EUS-guided biliary drainage with a fully covered metal stent as a novel route for natural orifice transluminal endoscopic biliary interventions: a pilot study (with videos)
    Junbum Eum
    Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea
    Gastrointest Endosc 72:1279-84. 2010
    EUS-guided biliary drainage (EUS-BD) with the use of a fully covered metal stent can result in a large-diameter fistula between the bile duct and the duodenum or stomach...
  92. pmc Pre-hospital and in-hospital thoracostomy: indications and complications
    Christopher J Aylwin
    Trauma Service, Department of Surgery, Royal London Hospital, London, UK
    Ann R Coll Surg Engl 90:54-7. 2008
    Pleural drainage with chest tube insertion for thoracic trauma is a common and often life-saving technique. Although considered a simple procedure, complication rates have been reported to be 2-25%...
  93. doi Pleural decompression and drainage during trauma reception and resuscitation
    M Fitzgerald
    Emergency and Trauma Centre, The Alfred Hospital, Melbourne, Australia
    Injury 39:9-20. 2008
    This review examines pleural decompression and drainage during initial hospital adult trauma reception and resuscitation, when it is indicated for haemodynamically unstable patients with signs of pneumothorax or haemothorax...
  94. ncbi Transgastric pancreatography and EUS-guided drainage of the pancreatic duct
    Uwe Will
    Department of Internal Medicine III, Municipal Hospital, Strasse des Friedens, 122, D 07548, Gera, Germany
    J Hepatobiliary Pancreat Surg 14:377-82. 2007
    Endoscopic transpapillary drainage of the retained pancreatic duct in symptomatic patients with chronic pancreatitis is considered an established treatment option...
  95. doi Pneumothorax following thoracentesis: a systematic review and meta-analysis
    Craig E Gordon
    Renal Section, Department of Medicine, Boston University Medical Center, Boston, MA 02118, USA
    Arch Intern Med 170:332-9. 2010
    ..We aimed to determine the mean pneumothorax rate following thoracentesis and to identify risk factors for pneumothorax through a systematic review and meta-analysis...
  96. pmc Pelvic drainage and other risk factors for leakage after elective anterior resection in rectal cancer patients: a prospective study of 978 patients
    Chien Yuh Yeh
    Department of Surgery, Colorectal Section of Chang Gung Memorial Hospital, at Linko, Taiwan
    Ann Surg 241:9-13. 2005
    The objective of this study was to investigate prophylactic pelvic drainage and other factors that might be associated with anastomotic leakage after elective anterior resection of primary rectal cancer.
  97. ncbi An artificial vascular graft is a useful interpositional material for drainage of the right anterior section in living donor liver transplantation
    Nam Joon Yi
    Department of Surgery, Seoul National University College of Medicine, Seoul, Korea
    Liver Transpl 13:1159-67. 2007
    ..An expanded polytetrafluoroethylene (ePTFE) graft may be used for anterior section drainage. Between February and November 2005, 26 recipients underwent RL liver transplantation draining MHV branches with ..
  98. ncbi Prevention of external ventricular drain--related ventriculitis
    A M Korinek
    Neuroanaesthesia Unit, Department of Anaesthesiology, Pitie Salpetriere University Hospital, University of Paris VI, Paris, France
    Acta Neurochir (Wien) 147:39-45; discussion 45-6. 2005
    ....
  99. ncbi Treatment of breast-cancer-related lymphedema with or without manual lymphatic drainage--a randomized study
    L Andersen
    Department of Oncology, Aarhus University Hospital, Denmark
    Acta Oncol 39:399-405. 2000
    A prospective randomized study was carried out to investigate whether the addition of manual lymphatic drainage (MLD) to the standard therapy could improve treatment outcome in women with lymphedema of the ipsilateral arm after breast ..
  100. ncbi Tranexamic acid decreases external blood loss but not hidden blood loss in total knee replacement
    L Good
    Department of Orthopaedics, Faculty of Health Sciences, University of Linkoping, Sweden
    Br J Anaesth 90:596-9. 2003
    ..Tranexamic acid decreases the external blood loss. Some blood loss may be concealed, and the overall effect of tranexamic acid on the haemoglobin (Hb) balance is not known...
  101. doi Is percutaneous drainage the new gold standard in the management of emphysematous pyelonephritis? Evidence from a systematic review
    Bhaskar K Somani
    University of Aberdeen, Aberdeen, Scotland, United Kingdom
    J Urol 179:1844-9. 2008
    ..We review the current management strategies including the role of nephron preserving percutaneous drainage in the treatment of emphysematous pyelonephritis.

Research Grants75

  1. Resuscitation of smoke inhalation and burn injury with a thioredoxin mimetic
    ANDREW LURIE SALZMAN; Fiscal Year: 2012
    ..the following indices: 1) Reduced lung inflammation and injury, as manifested in lung wet/dry ratio, lymphatic drainage, lipid peroxidation, airway obstruction, histologic scoring, PMN infiltration, ONOO- (3-nitrotyrosine, "3-NT") ..
  2. Gold Nanoparticle Assisted Delivery of Cancer Vaccines and Immune Stimulants
    Adam Lin; Fiscal Year: 2013
    ..Gold nanoparticles (AuNPs), on the other hand, have three advantages: potential lymph drainage due to their small size, simplistic synthesis/conjugation process and passively collection in antigen presenting ..
  3. Aqueous humor dynamics studies in vivo and in vitro
    PAUL LEON KAUFMAN; Fiscal Year: 2010
    ..third goal is to better understand the role of an important neurotransmitter (nitric oxide) in regulating normal and drug induced changes in aqueous humor formation and drainage in order to provide the basis for novel glaucoma therapies.
  4. Harness Germinal Matrix Hemorrhage
    John H Zhang; Fiscal Year: 2013
    ..of extracellular matrix (ECM) proteins, which obstruct the cerebroventricular system and impair CSF drainage. Thrombin participates in the proliferation of scar tissue by activating a subfamily of G protein-coupled ..
  5. Cellular Mechanisms of Lymphatic Muscle Contractility
    MICHAEL JOHN DAVIS; Fiscal Year: 2012
    ..to promote lymphangiogenesis in chronically edematous tissue, strategies to enhance lymphatic pump function and drainage of the affected regions are necessary...
  6. Utilization of calcite for the reduction of coal mine dust toxicity
    Xi Huang; Fiscal Year: 2010
    In the coal industry, calcite (CaCO3) is widely used to prevent explosions, treat acid mine drainage, and absorb acid rain components such as sulfur dioxide released during combustion...
  7. Matricellular Proteins in Trabecular Meshwork Increase Intraocular Pressure
    Douglas J Rhee; Fiscal Year: 2013
    ..Elevated intraocular pressure (IOP) is a causative risk factor and is due to altered drainage through the trabecular meshwork (TM)...
  8. Bronchial Vascular Proliferation and Function
    Elizabeth Wagner; Fiscal Year: 2012
    ..ELR+ CXC chemokines for the growth of new bronchial blood vessels, determine whether mediastinal lymph drainage provides a mechanism whereby parenchymal growth factors transit upstream to promote bronchial angiogenesis, and ..
  9. Angiopoietins in vascular and lymphatic remodeling of airways and lung
    Donald M McDonald; Fiscal Year: 2013
    ..lymphatic maturation and formation of specialized button-like endothelial junctions necessary for efficient fluid drainage. Aim #2 will also investigate the benefit of manipulating angiopoietin actions in pulmonary lymphangiectasia and ..
  10. Circulating miRNA as a biomarker for biliary atresia
    Joshua R Friedman; Fiscal Year: 2013
    ..This is successful in ~50% of cases (8-11), but even patients with apparently adequate biliary drainage may experience ongoing hepatic fibrosis and bile duct loss...
  11. ANTERIOR OCULAR SEGMENT PHYSIOLOGY AND PHARMACOLOGY
    Paul Kaufman; Fiscal Year: 2009
    ..of the physiological, pharmacological, neural and morphological mechanisms and responses governing aqueous humor drainage, and provide insights into the therapeutic and toxicological mechanisms of current and putative antiglaucoma ..
  12. Device to Improve Treatment of Colorectal Cancer Using O2 Dependent Phosphorescen
    JASON MATTHEW ZAND; Fiscal Year: 2010
    ..can cause a spectrum of morbidities to the patient including local abscess formation - requiring procedural drainage, tumor recurrence, debilitating pain, dysfunctional defecation, and overwhelming bacterial sepsis resulting in ..
  13. Chronic Rhinosinusitis Integrative Studies Program (CRISP)
    Robert P Schleimer; Fiscal Year: 2013
    ..It involves inflammation of the paranasal sinuses that results in facial pain/pressure, nasal and sinus drainage, smell loss, and nasal obstruction...
  14. Natural History of Urban Leptospirosis
    Albert Icksang Ko; Fiscal Year: 2013
    ..that effective prevention of urban leptospirosis requires providing slum communities with adequate sewage and drainage systems...
  15. Cellular Physiology of the Aqueous Outflow Pathway
    Haiyan Gong; Fiscal Year: 2013
    ..found, in mouse, bovine, monkey and human eyes, that only a fraction of outflow pathways actively contribute to drainage and termed those areas of outflow as the effective filtration area (EFA)...
  16. A novel device for improving sepsis outcomes through hemodynamic optimization
    Brett D Mensh; Fiscal Year: 2013
    ..Its innovative design combines fast pressure sensing functionality within the structure of a standard urinary drainage catheter...
  17. External Glaucoma Drainage Device
    Bruce Klitzman; Fiscal Year: 2012
    ..One of the primary reasons for surgical failure is the wound healing around the glaucoma drainage device (GDD) outflow path...
  18. Determining Molecular and Cellular Mechanisms of Glaucoma
    KAYARAT SAIDAS NAIR; Fiscal Year: 2013
    ..various anatomical and physiological factors, the iris is pushed forward causing physical blockage of the ocular drainage structure...
  19. Long-Acting Mucus-Penetrating Steroid Particles for Treatment of Eye Inflammation
    Hongming Chen; Fiscal Year: 2011
    ..comfort and localized action, are cleared from the ocular surface within minutes by lachrymation, blinking and drainage. Even highly potent anti-inflammatory corticosteroids must be instilled at least 4W/day at doses that compensate ..
  20. Reverse Engineering of Trabecular Meshwork
    Nils A Loewen; Fiscal Year: 2013
    ..9 million. Decreased drainage through a strainer-like structure called "trabecular meshwork" is responsible for the elevated eye pressure and ..
  21. The Development Epithelial Sodium Channel Blockers for Chronic Dry Eye
    Benjamin Yerxa; Fiscal Year: 2011
    ..volume of tear film on the ocular surface represents a balance between tear fluid output versus fluid loss via drainage, evaporation, or epithelial absorption...
  22. A new class of biodegradable synthetic biomaterial for seroma prevention
    Michael Craven; Fiscal Year: 2012
    ..incidence of seroma formation and the resulting increase in patient morbidity has led to the widespread use of drainage to treat seroma after formation...
  23. The Development Epithelial Sodium Channel Blockers for Chronic Dry Eye
    KARL H DONN; Fiscal Year: 2010
    ..volume of tear film on the ocular surface represents a balance between tear fluid output versus fluid loss via drainage, evaporation, or epithelial absorption...
  24. Development of an anti-bias caster system
    TODD HARGRODER; Fiscal Year: 2010
    ..of travel) are necessary to transitions from one grade to another, and cross-slopes are required for water drainage. Although the ADA accessibility guidelines place upper limits on the allowable angle of these slopes, these ..
  25. The Role of Lymphangiogenesis in IBD Pathogenesis
    Claudio Fiocchi; Fiscal Year: 2013
    ..that is beneficial when properly regulated but, if persistent or dysregulated, results in impaired lymphatic drainage and contributes to exacerbate inflammation...
  26. Ultrasound application in treatment of intra-cranial hemorrhage
    DOUGLAS R HANSMANN; Fiscal Year: 2010
    ..of EKOS ultrasound micro catheter, designed for treatment of ischemic stroke and an external ventricular drainage catheter. This combination was perceived quite challenging for use by clinicians...
  27. Real time imaging of the aqueous outflow pathway by two-photon endoscopy
    Hiroshi Nakamura; Fiscal Year: 2009
    ..HEALTH RELEVANCE: The elevation of intraocular pressure often associated with glaucoma is related to reduced drainage of the aqueous humor fluid from the eye...
  28. Implantable Microdevice for the Treatment of Hydrocephalus
    HONGSEOK NOH; Fiscal Year: 2009
    ..The shunt device consists of a one-way valve and two long tubes connected to the ventricular space and the drainage space, respectively...
  29. 5Lipoxygenase-mediated vasculopathy in HHcy
    Domenico Pratico; Fiscal Year: 2013
    ..Once formed Abeta is rapidly eliminated along perivascular lymphatic drainage pathways...
  30. Novel Wound Powder RGN107 to Reduce Wound Odor, Pain and Exudate at End-of-Life
    Teresa J Kelechi; Fiscal Year: 2013
    ..care research on feasible comfort measures is minimal to address physical symptoms such as pain, odor, and wound drainage (exudate) that often accompany wounds that develop at the end of life...
  31. Bacterial Interference to Prevent Catheter-Associated Urinary Tract Infection
    BARBARA WELLS TRAUTNER; Fiscal Year: 2013
    ..coli HU2117. Subjects will be >50 years of age, dependent upon long-term catheters for bladder drainage, and will have baseline bacteriuria...
  32. Continuous Real Time CSF Shunt Flow Monitor ShuntCheck
    Marek Swoboda; Fiscal Year: 2013
    ..ongoing clinical management of shunted patients is complex (due to a lack of tools for investigating CSF over drainage, for assessing the performance of specific shunt valves and siphon control devices and for streamlining the ..
  33. Clot Lysis: Evaluating Accelerated Resolution of IVH Phase III (CLEAR III)
    Daniel F Hanley; Fiscal Year: 2013
    ..Current therapy which uses extraventricular drainage (EVD) neither improves long-term survival nor alters the effect of blood on tissue...
  34. SIGNIFICANCE OF IMMUNOLOGICAL SEQUESTRATION IN THE EYE
    DALE SANNES GREGERSON; Fiscal Year: 2010
    ..which reduces lymphocytic perusal of the retina, minimizes leakage of antigens, and limits conventional lymphatic drainage. Based on our recent results, we propose that the lack of local antigen presenting cells is an important ..
  35. A Thermo-responsive Biopharmaceutical to Enhance the Tear Production of Lacritin
    Sandeep Samudre; Fiscal Year: 2013
    ..A major limitation of the ocular topical route is the rapid loss of drug via tearing and nasolacrimal drainage, requiring the use of frequent dosing and high drug concentrations that then create formulation difficulties, ..
  36. Biochemical Markers in Adult Patients with Aneurysmal Subarachnoid Hemorrhage
    Stephen B Lewis; Fiscal Year: 2010
    ..Collecting CSF samples for biomarker testing among TBI patients is a challenge, as not all patients need routine drainage and the overall population is varied because many patients sustain a serious concurrent injury...
  37. Therapy for Secondary Lymphedema in Breast Cancer
    Annissa Furr; Fiscal Year: 2013
    ..This work will ultimately reduce post-treatment costs associated with breast cancer, and may be applied to other conditions to promote lymphatic regrowth and appropriate drainage of interstitial fluid.
  38. Novel Optical Microprobes for Ultra-Precise Intraocular Laser Surgery
    Vasily N Astratov; Fiscal Year: 2010
    ..such as corneal surgery, lens removal, glaucoma filtration procedures, choroidotomy for subretinal fluid drainage, and vitreous removal...
  39. Engineering Functional Lymphatic Networks in Vitro
    JOE Y TIEN; Fiscal Year: 2010
    ..collagen gels as scaffolds and to manipulate the microenvironmental conditions to mimic native lymphatic drainage conditions in vivo...
  40. Gown and Glove Use to Prevent the Spread of Infection in VA Community Living Cent
    Mary Claire Roghmann; Fiscal Year: 2013
    ..upon healthcare personnel for healthcare and activities of daily living or residents whose secretions or drainage cannot be contained)...
  41. eNOS-Dependent Mechanoregulation of Intraocular Pressure
    W Daniel Stamer; Fiscal Year: 2013
    ..While the etiology of ocular hypertension in glaucoma is known to involve the conventional drainage pathway, the cellular mechanisms responsible for generation of this extra resistance are unknown...
  42. Development of Double Lumen Cannula for Percutaneous Right Heart Support
    Bill Sidor; Fiscal Year: 2012
    ..The DLC consists of main DLC body extension infusion cannula. The drainage lumen opens in the RA to drain total venous return from both the SVC and IVC, while the infusion cannula extends ..
  43. Targeting the Anterior Segment with Homing Peptides from Phage Display
    Donna M Peters; Fiscal Year: 2013
    ..Although reduced drainage of aqueous humor through the TM accounts for at least 90% of abnormalities resulting in glaucoma, there are very ..
  44. Treatment of Cerebral Edema using Ventricular Therapy
    JIM STICE; Fiscal Year: 2013
    ..clinical data to support the design of a pivotal study intended to demonstrate RVOT superiority to conventional drainage. ICP will be the primary endpoint. Study results will be used to support a FDA 510(k) product approval...
  45. CEREBROSPINAL FLUID MONITOR AND CONTROL SYSTEM FOR HYDROCEPHALUS
    Sukhraaj Basati; Fiscal Year: 2012
    ..Improper settings may lead to over- or under-drainage of the brain ventricles, which can lead to death if untreated...
  46. Long Term Implantable ICP Monitor for Hydrocephalus Patients
    Marek Swoboda; Fiscal Year: 2013
    ..ongoing clinical management of shunted patients is complex (due to a lack of tools for investigating CSF over-drainage and for assessing the performance of specific shunt valves and siphon control devices)...
  47. Continuous Real Time CSF Shunt Flow Monitor ShuntCheck
    Marek Swoboda; Fiscal Year: 2011
    ..ongoing clinical management of shunted patients is complex (due to a lack of tools for investigating CSF over drainage, for assessing the performance of specific shunt valves and siphon control devices and for streamlining the ..
  48. A Desktop Assembly and Analysis Pipeline for Next-gen Metagenomic Sequencing
    TIMOTHY J DURFEE; Fiscal Year: 2011
    ..and archaeal communities have been identified in virtually every ecological niche examined, from acid mine drainage to tropospheric clouds to the human body...
  49. Engineering a Functional Liver Graft for Treatment of End Stage Liver Disease
    DENVER MICHAEL FAULK; Fiscal Year: 2013
    ..liver ECM scaffolds retain the three-dimensional macrostructure, the native microvascular network, and the bile drainage system;allowing for complete recellularization of all native cell types, and 3) liver regeneration can be ..
  50. Accelerated Neuro-MRA Using Compressed Sensing and Constrained Reconstruction
    PATRICK ALAN TURSKI; Fiscal Year: 2013
    ..The speed of MRI is often not enough to visualize the arterial inputs and venous drainage of arterial-venous malformations (AVM)...
  51. Clinical Trial for CA-MRSA Infections
    DENISE TRITT; Fiscal Year: 2011
    ..unreadable] To compare the efficacy of clindamycin and trimethoprim-sulfmethoxazole in conjunction with surgical drainage for suppurative uncomplicated skin and soft tissue infections...
  52. Targeted nanoscale antigen arrays for treating autoimmune diseases
    Cory Berkland; Fiscal Year: 2012
    ..When properly designed, these nanomaterials facilitate: 1) drainage to lymph nodes (site of antigen priming) and 2) multivalent presentation of both antigen and an immune cell ..
  53. Functional Imaging of Tumor-Associated Lymphatics
    Sunkuk Kwon; Fiscal Year: 2013
    ..the same approach was employed in mice with extensive lymph node (LN) metastasis to image alteration of lymphatic drainage pathways and lymphatic contractile activity...
  54. PAI-1 Targeted Intrapleural Fibronolytic Therapy
    Andrey Komissarov; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Pleural drainage is required for complicated parapneumonic effusions and empyema in up to 40,000 US patients annually...
  55. Prevention of RGC loss in an in vitro excitotoxic model and an in vivo model of g
    Cindy L Linn; Fiscal Year: 2012
    ..using the hypertonic saline model, where 2M hypertonic saline is injected into episcleral veins to decrease the drainage through the trabecular meshwork, resulting in a slow increase in intraocular pressure, the primary risk factor ..
  56. REFLEXES IN LEFT VENTRICULAR DYSFUNCTION
    CHULANI KAPPAGODA; Fiscal Year: 2003
    ..by activation of renal C fiber afferents, and e) the diuresis is associated with obstruction of pulmonary lymph drainage is absent...
  57. Telemetric Implantable Intraocular Pressure Sensor Syste
    LAWRENCE WAN; Fiscal Year: 2003
    ..a new and unique miniature ophthalmic lOP sensor, to be retrofitted into the cannula of a conventional Glaucoma Drainage Device and surgically implanted under the sclera for the purpose of continuous measurement and transmission of ..
  58. A Device to Reduce Anastomotic Failure in the Treatment of Colorectal Cancer
    JASON ZAND; Fiscal Year: 2009
    ..can cause a spectrum of morbidities to the patient including local abscess formation - requiring procedural drainage, tumor recurrence, debilitating pain, dysfunctional defecation, and overwhelming bacterial sepsis resulting in ..
  59. LUNG FUNCTION IN PROLONGED HEART FAILURE
    Marie Francoise Doursout; Fiscal Year: 2004
    ..Limited lung lymphatic drainage may contribute to the pulmonary edema in some types of heart failure...
  60. Lymphangiogenesis and Angiogenesis in Airway Inflammation
    Donald McDonald; Fiscal Year: 2009
    ..hypothesis is that persistent airway inflammation leads to abnormalities in mucosal lymphatics that impair fluid drainage, and could lead to bronchial lymphedema, which worsens airway obstruction and perturbs immune responses by ..
  61. Development of the PathLock biasing caster system Phase 2
    TODD HARGRODER; Fiscal Year: 2013
    ..of travel) are necessary to transitions from one grade to another, and cross-slopes are required for water drainage. Although the ADA accessibility guidelines place upper limits on the allowable angle of these slopes these limits ..
  62. Amniotic Membrane versus Pericardium in Reducing Glaucoma Drainage Tube Exposure
    HOSAM EL SHEHA; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Glaucoma drainage devices (GDDs) have widely been used in the treatment of high-risk refractory glaucoma...
  63. Value Added Product Generation from ARD
    Pat James; Fiscal Year: 2011
    ..This is particularly valuable for the many abandoned mines leaking toxic Acid Rock Drainage (ARD) Nation-wide and for which no economic incentive to correct presently exists (i.e...
  64. COATING OF URINARY PROTHESES TO PREVENT ENCRUSTATION
    Harmeet Sidhu; Fiscal Year: 2000
    ..and nephrological medicine for the management of urinary and peritoneal dialysis flow, haemodialysis, and drainage of renal calculi following laser or lithotripsy treatment...
  65. MASSAGE THERAPY FOR EXPERIMENTAL LYMPHEDEMA
    Marlys Witte; Fiscal Year: 2002
    DESCRIPTION (Applicant's Abstract): Massage therapy (in the form of Manual Lymph Drainage (MLD) or Manual Lymphedema Treatment (MLT) is an integral component of the international consensus-recommended optimal treatment for lymphedema(LE) ..
  66. NOVEL ACCESSORY FOR URINARY LEG BAGS
    SHANTHA SARANGAPANI; Fiscal Year: 1999
    Urinary drainage bags called leg bags are commonly used with permanent indwelling catheters in patients, with incontinence or chronic disabilities, at rehabilitation centers or hospitals...
  67. Mentored Patient-Oriented Research Career Development Aw
    Kelly Young; Fiscal Year: 2004
    ..g., laceration repair, fracture reduction, incision and drainage of an abscess, lumbar puncture) will be studied...
  68. Nitric Oxide and Chronic Rhinosinusitis
    Abraham Jacob; Fiscal Year: 2001
    ..population and is the reason for approximately 12-million physician office visits annually. Obstruction to sinus drainage and immune dysregulation are believed to result in mucosal disruption and hypersecretion, nasal obstruction, ..
  69. SURGERY FOR NEC IN HUMAN INFANTS-- A RANDOMIZED TRIAL
    R Moss; Fiscal Year: 2002
    ..Simple primary peritoneal drainage (PPD) of the abdominal cavity is a novel, minimally invasive alternative...
  70. Stent Lock Mechanism for Transcutaneous Catheters
    NICHOLAS VITALE; Fiscal Year: 2005
    ..access for chemotherapy, transcutaneous intrathoracic access of cardiac power lines, and suprapubic bladder drainage are among the clinical applications where transcutaneous catheters are routinely used in the course of treatment...
  71. Amniotic Membrane Patch Graft to Cover Glaucoma Drainage Tube
    HOSAM EL SHEHA; Fiscal Year: 2009
    Glaucoma drainage devices (GDDs) have widely been used in the treatment of high risk refractory glaucoma...
  72. FACILITY RENOVATION AND ANNENBERG CAGE WASH FACILITIY
    Kenneth Davis; Fiscal Year: 2003
    ..to this problem will be removing the existing floor, installing a new moisture barrier, and refashioning the drainage collection system. 3) One HVAC fan supplies the East side of the vivarium animal rooms and cage wash area...
  73. Bronchial Angiogenesis in the Ischemic Lung
    Adlah Sukkar; Fiscal Year: 2007
    ..Specific Aim 2: To determine whether mediastinal lymph drainage provides a mechanism whereby parenchymal growth factors transit upstream to promote angiogenesis of larger ..
  74. FACTORS DETERMINING INTRAOCULAR PRESSURE
    Simon John; Fiscal Year: 2001
    ..occur in the ciliary epithelium that produces the ocular fluid (aqueous humor) and in cells of the aqueous humor drainage (outflow) pathway. Available evidence suggests that the NPs act to decrease IOP...
  75. Contrast-Enhanced Ultrasound Detection of Secondary Lymph Nodes
    Barry B Goldberg; Fiscal Year: 2010
    DESCRIPTION (provided by applicant): Accurate detection and characterization of lymph nodes that receive drainage from a primary cancer [i.e...