phytotherapy

Summary

Summary: Use of plants or herbs to treat diseases or to alleviate pain.

Top Publications

  1. ncbi Pharmacological and toxicological properties of Nigella sativa
    B H Ali
    Department of Veterinary Medicine, King Saud University, Buraydah, Al Gaseem 81999, Saudi Arabia
    Phytother Res 17:299-305. 2003
  2. ncbi Cancer chemoprevention with dietary phytochemicals
    Young Joon Surh
    College of Pharmacy, Seoul National University, Shinlim Dong, Kwanak Ku, Seoul 151 742, South Korea
    Nat Rev Cancer 3:768-80. 2003
  3. ncbi Anti-infective potential of natural products: how to develop a stronger in vitro 'proof-of-concept'
    Paul Cos
    Laboratory for Microbiology, Parasitology and Hygiene LMPH, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
    J Ethnopharmacol 106:290-302. 2006
  4. ncbi Synergy research: approaching a new generation of phytopharmaceuticals
    H Wagner
    Department of Pharmacy, Center of Pharma Research, Ludwig Maximilians University, Butenandtstr 5 13, House B, D 81377 Munich, Germany
    Phytomedicine 16:97-110. 2009
  5. ncbi Medicinal plants of India with anti-diabetic potential
    J K Grover
    Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110049, India
    J Ethnopharmacol 81:81-100. 2002
  6. ncbi Systematic review of herbs and dietary supplements for glycemic control in diabetes
    Gloria Y Yeh
    Division for Research and Education in Complementary and Integrative Medical Therapies, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 26:1277-94. 2003
  7. ncbi Systematic review of randomized controlled trials evaluating the efficacy and safety of ginseng
    Nam Hun Lee
    Liver and Immunology Research Center, Daejeon Oriental Hospital of Daejeon University, Korea
    J Acupunct Meridian Stud 4:85-97. 2011
  8. ncbi Ethnobotanical study on traditional uses of wild medicinal plants in Prokletije Mountains (Montenegro)
    N Menkovic
    Institute for Medicinal Plants Research, Belgrade, Serbia
    J Ethnopharmacol 133:97-107. 2011
  9. ncbi Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels
    Martijn B Katan
    Division of Human Nutrition and Epidemiology, Wageningen University, Bomenweg 2, 6703 HD Wageningen, The Netherlands
    Mayo Clin Proc 78:965-78. 2003
  10. pmc Re-examining hypotheses concerning the use and knowledge of medicinal plants: a study in the Caatinga vegetation of NE Brazil
    Ulysses Paulino de Albuquerque
    Laboratório de Etnobotânica Aplicada, Área de Botânica, Departamento de Biologia, Universidade Federal Rural de Pernambuco, Rua Dom Manoel de Medeiros s n, Dois Irmãos Recife Pernambuco, 52171 030, Brasil
    J Ethnobiol Ethnomed 2:30. 2006

Detail Information

Publications364 found, 100 shown here

  1. ncbi Pharmacological and toxicological properties of Nigella sativa
    B H Ali
    Department of Veterinary Medicine, King Saud University, Buraydah, Al Gaseem 81999, Saudi Arabia
    Phytother Res 17:299-305. 2003
    ..It would appear that the beneficial effects of the use of the seeds and thymoquinone might be related to their cytoprotective and antioxidant actions, and to their effect on some mediators of inflammation...
  2. ncbi Cancer chemoprevention with dietary phytochemicals
    Young Joon Surh
    College of Pharmacy, Seoul National University, Shinlim Dong, Kwanak Ku, Seoul 151 742, South Korea
    Nat Rev Cancer 3:768-80. 2003
    ....
  3. ncbi Anti-infective potential of natural products: how to develop a stronger in vitro 'proof-of-concept'
    Paul Cos
    Laboratory for Microbiology, Parasitology and Hygiene LMPH, Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Universiteitsplein 1, 2610 Antwerp, Belgium
    J Ethnopharmacol 106:290-302. 2006
    ....
  4. ncbi Synergy research: approaching a new generation of phytopharmaceuticals
    H Wagner
    Department of Pharmacy, Center of Pharma Research, Ludwig Maximilians University, Butenandtstr 5 13, House B, D 81377 Munich, Germany
    Phytomedicine 16:97-110. 2009
    ..This new generation of phytopharmaceuticals could lend phytotherapy a new legitimacy and enable their use to treat diseases which have hitherto been treated using synthetic drugs ..
  5. ncbi Medicinal plants of India with anti-diabetic potential
    J K Grover
    Department of Pharmacology, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110049, India
    J Ethnopharmacol 81:81-100. 2002
    ..charantia, Eugenia jambolana, Mucuna pruriens, T. cordifolia, T. foenum graecum, O. sanctum, P. marsupium, Murraya koeingii and Brassica juncea. All plants have shown varying degree of hypoglycemic and anti-hyperglycemic activity...
  6. ncbi Systematic review of herbs and dietary supplements for glycemic control in diabetes
    Gloria Y Yeh
    Division for Research and Education in Complementary and Integrative Medical Therapies, Harvard Medical School, Boston, Massachusetts, USA
    Diabetes Care 26:1277-94. 2003
    ..To conduct a systematic review of the published literature on the efficacy and safety of herbal therapies and vitamin/mineral supplements for glucose control in patients with diabetes...
  7. ncbi Systematic review of randomized controlled trials evaluating the efficacy and safety of ginseng
    Nam Hun Lee
    Liver and Immunology Research Center, Daejeon Oriental Hospital of Daejeon University, Korea
    J Acupunct Meridian Stud 4:85-97. 2011
    ..In conclusion, our review compiles the evidence on the use of ginseng, finding a strong positive potential for glucose metabolism, psychomotor function, and pulmonary disease, but not for physical performance enhancement...
  8. ncbi Ethnobotanical study on traditional uses of wild medicinal plants in Prokletije Mountains (Montenegro)
    N Menkovic
    Institute for Medicinal Plants Research, Belgrade, Serbia
    J Ethnopharmacol 133:97-107. 2011
    ..Active ingredients of plant species officinal in European Pharmacopoeia 6.0 (Ph. Eur. 6.0) were studied and we assessed possibilities for commercial exploitation for local economic development...
  9. ncbi Efficacy and safety of plant stanols and sterols in the management of blood cholesterol levels
    Martijn B Katan
    Division of Human Nutrition and Epidemiology, Wageningen University, Bomenweg 2, 6703 HD Wageningen, The Netherlands
    Mayo Clin Proc 78:965-78. 2003
    ..However, present evidence is sufficient to promote use of sterols and stanols for lowering LDL cholesterol levels in persons at increased risk for coronary heart disease...
  10. pmc Re-examining hypotheses concerning the use and knowledge of medicinal plants: a study in the Caatinga vegetation of NE Brazil
    Ulysses Paulino de Albuquerque
    Laboratório de Etnobotânica Aplicada, Área de Botânica, Departamento de Biologia, Universidade Federal Rural de Pernambuco, Rua Dom Manoel de Medeiros s n, Dois Irmãos Recife Pernambuco, 52171 030, Brasil
    J Ethnobiol Ethnomed 2:30. 2006
    ..However, very little information is available concerning the interaction of people with the plants of the Caatinga...
  11. ncbi Synergy and other interactions in phytomedicines
    E M Williamson
    The School of Pharmacy, University of London, United Kingdom
    Phytomedicine 8:401-9. 2001
    ..Herbs discussed include Ginkgo biloba, Piper methysticum (Kava-Kava), Glycyrrhiza glabra, Hypericum perforatum, Valeriana officinalis, Cannabis sativa, Salix alba and others...
  12. pmc Ethnobotanical survey in Canhane village, district of Massingir, Mozambique: medicinal plants and traditional knowledge
    Ana Ribeiro
    Tropical Research Institute, Rua da Junqueira 86, 1300 344, Lisbon, Portugal
    J Ethnobiol Ethnomed 6:33. 2010
    ..The objective of this study was to organize a database of medicinal plants including their applications and associated procedures in Canhane village, district of Massingir, province of Gaza, Mozambique...
  13. ncbi Antimalarial activity of medicinal plants used in traditional medicine in S. Tomé and Príncipe islands
    Maria do Céu de Madureira
    Departamento de Farmacognosia, Faculdade de Farmacia, Universidade de Coimbra, R Norte, 3000 Coimbra, Portugal
    J Ethnopharmacol 81:23-9. 2002
    ..In vivo, the extracts caused partial reduction of Plasmodium berghei parasitaemia in mice...
  14. pmc Preparation and use of plant medicines for farmers' health in Southwest Nigeria: socio-cultural, magico-religious and economic aspects
    Taiwo E Mafimisebi
    Department of Agricultural Economics and Extension, School of Agriculture and Agricultural Technology, The Federal University of Technology, Akure, Nigeria
    J Ethnobiol Ethnomed 6:1. 2010
    ....
  15. pmc Ethnobotanical study of medicinal plants used by people in Zegie Peninsula, Northwestern Ethiopia
    Tilahun Teklehaymanot
    Endod and Other Medicinal Plants Unit, Aklilu Lemma Institute of Pathobiology, Addis Ababa University, PO Box 1176, Addis Ababa, Ethiopia
    J Ethnobiol Ethnomed 3:12. 2007
    ....
  16. ncbi Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease
    Ana García-Lafuente
    Centro para la Calidad de los Alimentos, Instituto Nacional de Investigacion y Tecnologia Agraria y Alimentaria INIA, Campus Universitario Duques de Soria, 42071, Soria, Spain
    Inflamm Res 58:537-52. 2009
    ..This review summarizes the known mechanisms involved in the anti-inflammatory activity of flavonoids and the implications of these effects on the protection against cancer and cardiovascular disease...
  17. ncbi Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component
    Anoja S Attele
    Tang Center for Herbal Medicine Research, The Pritzker School of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Diabetes 51:1851-8. 2002
    ..This antidiabetic effect of ginsenoside Re was not associated with body weight changes, suggesting that other constituents in the extract have distinct pharmacological mechanisms on energy metabolism...
  18. ncbi St John's wort: Prozac from the plant kingdom
    G Di Carlo
    Department of Experimental Pharmacology, University of Naples Federico II, via D Montesano 49, 80131 Naples, Italy
    Trends Pharmacol Sci 22:292-7. 2001
    ..However, important herb--drug interactions have been described. In view of its efficacy and safety records, St John's wort should be considered for the first-line treatment of mild to moderate depression...
  19. ncbi Anti-inflammatory compounds of plant origin. Part II. modulation of pro-inflammatory cytokines, chemokines and adhesion molecules
    João B Calixto
    Department of Pharmacology, CCB, Universidade Federal de Santa Catarina UFSC, Florianopolis, SC, Brazil
    Planta Med 70:93-103. 2004
    ..PK:protein kinase PMA/TPA:phorbol myristate acetate RANTES:regulated upon activation normal T-cell expressed and secreted TGF-beta:transforming growth factor-beta TNFalpha:tumour necrosis factor VCAM-1:vascular cell adhesion molecule-1..
  20. ncbi Therapeutic applications of pomegranate (Punica granatum L.): a review
    Julie S Jurenka
    Thorne Research, PO Box 25, Dover, ID 83825, USA
    Altern Med Rev 13:128-44. 2008
    ..Other potential applications include infant brain ischemia, male infertility, Alzheimer's disease, arthritis, and obesity...
  21. ncbi Complementary/alternative medicine for hypertension: a mini-review
    Edzard Ernst
    Complementary Medicine, Peninsula Medical School, Exeter, United Kingdom
    Wien Med Wochenschr 155:386-91. 2005
    ..The most encouraging data pertain to garlic, autogenic training, biofeedback and yoga. More research is required before firm recommendations can be offered...
  22. ncbi Ethnoveterinary medicinal plants at Bale Mountains National Park, Ethiopia
    Haile Yineger
    Department of Biology, Jimma University, P O Box 5195, Jimma, Ethiopia
    J Ethnopharmacol 112:55-70. 2007
    ..76%) followed by dermal (55 species, 36.18%). Indigenous knowledge was mostly transferred to an elect of a family member in word of mouth indicating that it was prone to fragmentation or loss...
  23. ncbi Hypoglycemic and antioxidant effect of oleuropein in alloxan-diabetic rabbits
    Hasan Fayadh Al-Azzawie
    Biochemistry Department, College of Science, University of Baghdad, Baghdad, Iraq
    Life Sci 78:1371-7. 2006
    ....
  24. pmc The ethnomedicine of the Haya people of Bugabo ward, Kagera Region, north western Tanzania
    Mainen J Moshi
    Department of Biological and Preclinical Studies, Institute of Traditional Medicine, MUHAS, P, O, Box 65001, Dar es Salaam, Tanzania
    J Ethnobiol Ethnomed 5:24. 2009
    ..As an initiative in that direction, this study documented the knowledge on medicinal plant use by traditional healers of Bugabo Ward in Bukoba District...
  25. ncbi Traditional phytotherapy and trans-cultural pharmacy among Turkish migrants living in Cologne, Germany
    Andrea Pieroni
    SCH Group, Department of Social Sciences, Wageningen University and Research Centre, Postbus 8060, NL 6700 DA Wageningen, The Netherlands
    J Ethnopharmacol 102:69-88. 2005
    ..of Pistacia terebinthus and the seeds of Peganum harmala from the perspective of modern phytopharmacology, phytotherapy and toxicology...
  26. ncbi Herbal medicines and perioperative care
    M K Ang-Lee
    Department of Anesthesia and Critical Care, University of Chicago, 5841 S Maryland Ave, MC 4028, Chicago, IL 60637, USA
    JAMA 286:208-16. 2001
    ..Widespread use of herbal medications among the presurgical population may have a negative impact on perioperative patient care...
  27. ncbi Antioxidant, antimicrobial, antiulcer and analgesic activities of nettle (Urtica dioica L.)
    Ilhami Gulcin
    Department of Chemistry, Faculty of Science and Arts, Ataturk University, 25240 Erzurum, Turkey
    J Ethnopharmacol 90:205-15. 2004
    ..WEN also showed antimicrobial activity against nine microorganisms, antiulcer activity against ethanol-induced ulcerogenesis and analgesic effect on acetic acid-induced stretching...
  28. ncbi Medicinal properties of Echinacea: a critical review
    B Barrett
    Department of Family Medicine, University of Wisconsin Medical School, Madison WI 53715, USA
    Phytomedicine 10:66-86. 2003
    ..Hence, while there is a great deal of moderately good-quality scientific data regarding E. purpurea, effectiveness in treating illness or in enhancing human health has not yet been proven beyond a reasonable doubt...
  29. ncbi Efficacy and tolerance of a comfrey root extract (Extr. Rad. Symphyti) in the treatment of ankle distorsions: results of a multicenter, randomized, placebo-controlled, double-blind study
    R Koll
    Merck Selbstmedikation GmbH, Roesslerstr 96, D 64293 Darmstadt, Germany
    Phytomedicine 11:470-7. 2004
    ..The good local and global tolerance of the trial medication could also be confirmed. The study results are consistent with the known pre-clinical and clinical data concerning comfrey...
  30. ncbi Efficacy of a comfrey root extract ointment in comparison to a diclofenac gel in the treatment of ankle distortions: results of an observer-blind, randomized, multicenter study
    H G Predel
    Merck Selbstmedikation GmbH, Roesslerstr 96, D 64293 Darmstadt, Germany
    Phytomedicine 12:707-14. 2005
    ..01-103.09h*N/cm2 and was completely above the margin of non-inferiority. Moreover, the results of the primary and secondary variables indicate that Comfrey extract may be superior to Diclofenac gel...
  31. ncbi Ethnobotanical study of knowledge and medicinal plants use by the people in Dek Island in Ethiopia
    Tilahun Teklehaymanot
    Endod and Other Medicinal Plants Unit, Aklilu Lemma Institute of Pathobiology, Addis Ababa University, P O Box 1176, Addis Ababa, Ethiopia
    J Ethnopharmacol 124:69-78. 2009
    ..It reveals the trend of knowledge of medicinal plants and the documentation serves as a baseline data for future phytochemical and pharmacological studies...
  32. ncbi An ethnobotanical study on the usage of wild medicinal herbs from Kopaonik Mountain (Central Serbia)
    Snezana Jarić
    Department of Ecology, The Sinisa Stanković Institute for Biological Research, University of Belgrade, Bulevar Despota Stefana 142, Belgrade, Serbia and Montenegro
    J Ethnopharmacol 111:160-75. 2007
    ..rheumatism and skin ailments) and Ficaria verna Huds. (tubers for treating haemorrhoids). In addition, 10 wild species used in veterinary medicine, as well as 25 herbs used for human nourishment were noted...
  33. ncbi Psidium guajava: a review of its traditional uses, phytochemistry and pharmacology
    Rosa Martha Perez Gutierrez
    Laboratorio de Investigacion de Productos Naturales, Escuela Superior de Ingenieria Quimica e Industrias Extractivas IPN, Punto fijo 16, Col Torres Lindavista C P 07708 Mexico, D F, Mexico
    J Ethnopharmacol 117:1-27. 2008
    ..Suggest a wide range of clinical applications for the treatment of infantile rotaviral enteritis, diarrhoea and diabetes...
  34. pmc An ethnobotanical study of medicinal plants used by local people in the lowlands of Konta Special Woreda, southern nations, nationalities and peoples regional state, Ethiopia
    Tesfaye Hailemariam Bekalo
    Louis Dreyfus Commodities Coffee Division, Addis Ababa, Ethiopia
    J Ethnobiol Ethnomed 5:26. 2009
    ..Therefore, this research was conducted to investigate medicinal plants of the Konta people and to document the local knowledge before environmental and cultural changes deplete the resources...
  35. ncbi Use of complementary and alternative medicine by chinese women with breast cancer
    Yong Cui
    Department of Medicine, Center for Health Services Research and Vanderbilt Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232 8300, USA
    Breast Cancer Res Treat 85:263-70. 2004
    ..Given the high prevalence of CAM use among breast cancer patients, research is urgently needed to systematically evaluate the efficacy and safety of CAM use, particularly use of herbal medicines...
  36. ncbi Astragalus-based Chinese herbs and platinum-based chemotherapy for advanced non-small-cell lung cancer: meta-analysis of randomized trials
    Michael McCulloch
    University of California, Berkeley School of Public Health, Division of Epidemiology, Berkeley, CA 94720, USA
    J Clin Oncol 24:419-30. 2006
    ....
  37. ncbi Carbon tetrachloride-induced nephrotoxicity in rats: protective role of Digera muricata
    Muhammad R Khan
    Department of Biochemistry, Faculty of Biological Sciences, Quaid i Azam University, Islamabad 4400, Pakistan
    J Ethnopharmacol 122:91-9. 2009
    ....
  38. ncbi Mountain ginseng extract exhibits anti-lung cancer activity by inhibiting the nuclear translocation of NF-κB
    Jeong Won Hwang
    Division of Life Science, Korea Basic Science Institute, Gwahangno 169 148, Yuseong Gu, Daejeon, Republic of Korea
    Am J Chin Med 40:187-202. 2012
    ..These results suggest that BX-MG inhibits lung cancer cell growth by activating tumor suppressors and inhibiting nuclear translocation of NF-κB...
  39. pmc Herbal medicine use in the districts of Nakapiripirit, Pallisa, Kanungu, and Mukono in Uganda
    John R S Tabuti
    Makerere University, College of Agricultural and Environmental Sciences MUCAES, P O Box 7062, Kampala, Uganda
    J Ethnobiol Ethnomed 8:35. 2012
    ..This study was conducted to document the IK relevant to traditional medicine in the districts of Mukono, Nakapiripirit, Kanungu and Pallisa, in Uganda...
  40. ncbi Identification of bioactive constituents of Ziziphus jujube fruit extracts exerting antiproliferative and apoptotic effects in human breast cancer cells
    Pierluigi Plastina
    Department of Pharmaceutical Sciences, University of Calabria, 87036 Arcavacata di Rende, Cosenza, Italy
    J Ethnopharmacol 140:325-32. 2012
    ..Ziziphus extracts have been used in Traditional Chinese Medicine for the treatment of cancer...
  41. ncbi Review of current and "omics" methods for assessing the toxicity (genotoxicity, teratogenicity and nephrotoxicity) of herbal medicines and mushrooms
    Moustapha Ouédraogo
    Laboratory of Pharmacology and Toxicology, Health Sciences Faculty, University of Ouagadougou, 03 BP 7021 Ouagadougou 03, Burkina Faso mustapha
    J Ethnopharmacol 140:492-512. 2012
    ....
  42. ncbi Medicinal utilization of exotic plants by Bapedi traditional healers to treat human ailments in Limpopo province, South Africa
    Sebua Semenya
    Department of Biodiversity, University of Limpopo, Private Bag X1106, Sovenga 0727, South Africa
    J Ethnopharmacol 144:646-55. 2012
    ..The medicinal uses of most of these species have neither been documented nor their biological activity evaluated...
  43. pmc Phase II randomized, placebo-controlled trial of green tea extract in patients with high-risk oral premalignant lesions
    Anne S Tsao
    Department of Thoracic Head and Neck Medical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer Prev Res (Phila) 2:931-41. 2009
    ..Higher doses of GTE may improve short-term (12-week) OPL outcome. The present results support longer-term clinical testing of GTE for oral cancer prevention...
  44. ncbi Hypoglycemic effect of bitter melon compared with metformin in newly diagnosed type 2 diabetes patients
    Anjana Fuangchan
    Department of Pharmacy Practice, Faculty of Pharmaceutical Sciences, Naresuan University, Muang, Phitsanulok 65000, Thailand
    J Ethnopharmacol 134:422-8. 2011
    ..has been widely used as an traditional medicine treatment for diabetic patients in Asia. In vitro and animal studies suggested its hypoglycemic activity, but limited human studies are available to support its use...
  45. ncbi The use of teetaimed in Estonia, 1880s-1990s
    Renata Sõukand
    Estonian Literary Museum, Vanemuise 42, Tartu 51003, Estonia
    Appetite 59:523-30. 2012
    ..Hence, the roots of the Estonian tea tradition lie in the medicinal use of the plants, not oriental ceremonial tea drinking...
  46. ncbi Overview for various aspects of the health benefits of Piper longum linn. fruit
    Suresh Kumar
    Department of Pharmaceutical Sciences, Guru Jambheshwar University of Science and Technology, Hisar, India
    J Acupunct Meridian Stud 4:134-40. 2011
    ..longum fruit, including phytochemistry, pharmacological profile and safety profile. In view of the commercial, economic, and medicinal importance of the P. longum plant, it is useful for researchers to study the plant in detail...
  47. ncbi Anti-diabetic and hypoglycaemic effects of Momordica charantia (bitter melon): a mini review
    Lawrence Leung
    Department of Family Medicine, Centre for Studies in Primary Care, Queen s University, Kingston, ON, Canada
    Br J Nutr 102:1703-8. 2009
    ..The present article reviews the clinical data regarding the anti-diabetic potentials of M. charantia and calls for better-designed clinical trials to further elucidate its possible therapeutic effects...
  48. ncbi Evaluation of cell death caused by an ethanolic extract of Serenoae repentis fructus (Prostasan) on human carcinoma cell lines
    Katarina Hostanska
    University Hospital Zurich, Department of Internal Medicine, Institute for Complementary Medicine, Ramistrasse 100, 8091 Zurich, Switzerland
    Anticancer Res 27:873-81. 2007
    b>Phytotherapy is a third approach for treating lower urinary tract symptoms associated with benign prostatic hyperplasia (BPH)...
  49. ncbi Naturally occurring antinociceptive substances from plants
    J B Calixto
    Department of Pharmacology, CCB, Universidade Federal de Santa Catarina, Florianopolis, SC, Brazil
    Phytother Res 14:401-18. 2000
    ..Plant-derived substances have, and will certainly continue to have, a relevant place in the process of drug discovery, particularly in the development of new analgesic drugs...
  50. pmc Evaluation of Abelmoschus moschatus extracts for antioxidant, free radical scavenging, antimicrobial and antiproliferative activities using in vitro assays
    Mir Z Gul
    Department of Plant Sciences, School of Life Sciences, University of Hyderabad, Gachibowli, Hyderabad 500 046, India
    BMC Complement Altern Med 11:64. 2011
    ..To give a scientific basis for traditional usage of this medicinal plant, the seed and leaf extracts were evaluated for their antioxidant, free radical scavenging, antimicrobial and antiproliferative activities...
  51. ncbi Plants used for treating respiratory infections in rural Maputaland, KwaZulu-Natal, South Africa
    T York
    Department of Botany, University of Zululand, Private Bag 1001, KwaDlangezwa 3886, South Africa
    J Ethnopharmacol 135:696-710. 2011
    ..Novel information gathered from surveys like the present study is important in preserving indigenous knowledge...
  52. pmc Medical pluralism on Mfangano Island: use of medicinal plants among persons living with HIV/AIDS in Suba District, Kenya
    Jason M Nagata
    Institute of Social and Cultural Anthropology, University of Oxford, 51 Banbury Road, Oxford OX6 6PE, UK
    J Ethnopharmacol 135:501-9. 2011
    ..Using a cross-sectional study we sought to document and identify the herbal medicines used by persons living with HIV/AIDS on Mfangano Island, Suba District, Nyanza Province, Kenya...
  53. ncbi Drug development from natural products: exploiting synergistic effects
    Gudrun Ulrich-Merzenich
    Medical Policlinic of the Rheinische Friedrich Wilhelms University of Bonn, Wilhelmstr 35 37, D 53111 Bonn, Germany
    Indian J Exp Biol 48:208-19. 2010
    ..But traditional systems of medicines like Ayurveda, traditional Chinese medicine or the European phytotherapy generally assume that a synergy of all ingredients of the plants will bring about the maximum of therapeutic ..
  54. ncbi Herbal therapy is associated with the risk of CKD in adults not using analgesics in Taiwan
    Jinn Yuh Guh
    Department of Internal Medicine, Faculty of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
    Am J Kidney Dis 49:626-33. 2007
    ..Several cases of Chinese herb nephropathy were reported in Taiwan. Therefore, we studied the association between herbal therapy and chronic kidney disease (CKD) in Taiwan...
  55. ncbi Complex interactions between phytochemicals. The multi-target therapeutic concept of phytotherapy
    Thomas Efferth
    Department of Pharmaceutical Biology, Institute of Pharmacy and Biochemistry, University of Mainz, Staudinger Weg 5, 55128 Mainz, Germany
    Curr Drug Targets 12:122-32. 2011
    ..b>Phytotherapy, whose therapeutic efficacy is based on the combined action of a mixture of constituents, offers new treatment ..
  56. ncbi Progallin A isolated from the acetic ether part of the leaves of Phyllanthus emblica L. induces apoptosis of human hepatocellular carcinoma BEL-7404 cells by up-regulation of Bax expression and down-regulation of Bcl-2 expression
    Zhen guo Zhong
    Center of Research and Development of New Drugs, Guangxi Traditional Chinese Medical University, Nanning 530001, Guangxi Zhuang Autonomous Region, China
    J Ethnopharmacol 133:765-72. 2011
    ..on apoptosis in human hepatocellular carcinoma BEL-7404 cells and its possible mechanisms, and to measure the immune toxicity of Progallin A in vitro...
  57. ncbi A review on biological, nutraceutical and clinical aspects of French maritime pine bark extract
    Alya Maimoona
    Department of Chemistry, Lahore College for Women University Lahore, Lahore, Pakistan alya
    J Ethnopharmacol 133:261-77. 2011
    ..Of these, two are about extraction advancement and analysis while the rest relate to its clinical, biological and nutraceutical aspects...
  58. pmc Ethnopharmacological survey among migrants living in the Southeast Atlantic Forest of Diadema, São Paulo, Brazil
    Daniel Garcia
    Department of Biology, Universidade Federal de Sao Paulo, Rua Arthur Ridel, 275 CEP, 09941 510, Diadema, SP, Brazil
    J Ethnobiol Ethnomed 6:29. 2010
    ..An ethnopharmacological survey conducted among migrants living in the Southeast Atlantic Forest remnants (Diadema, São Paulo, Brazil) is presented herein...
  59. ncbi Pharmacological basis for the medicinal use of black pepper and piperine in gastrointestinal disorders
    Malik Hassan Mehmood
    Natural Product Research Division, Department of Biological and Biomedical Sciences, Aga Khan University Medical College, Karachi, Pakistan
    J Med Food 13:1086-96. 2010
    ....
  60. ncbi The use of plants in the medical system of the Fulni-ô people (NE Brazil): a perspective on age and gender
    Ulysses Paulino de Albuquerque
    Departamento de Biologia, Área de Botânica, Laboratório de Etnobotânica Aplicada, Universidade Federal Rural de Pernambuco, Pernambuco, Brazil
    J Ethnopharmacol 133:866-73. 2011
    ..Additionally, this study seeks to identify the sites where these resources are collected...
  61. pmc Red ginseng for treating erectile dysfunction: a systematic review
    Dai Ja Jang
    Korea Food Research Institute, Sungnam, South Korea
    Br J Clin Pharmacol 66:444-50. 2008
    ..This systematic review evaluates the current evidence for the effectiveness of red ginseng for treating erectile dysfunction...
  62. ncbi Cross-cultural adaptation in urban ethnobotany: the Colombian folk pharmacopoeia in London
    Melissa Ceuterick
    Division of Pharmacy Practice, University of Bradford, Richmond Building, Richmond Road, Bradford BD7 1DP, West Yorkshire, UK
    J Ethnopharmacol 120:342-59. 2008
    ..To investigate traditional health care practices and changes in medicinal plant use among the growing Colombian community in London...
  63. ncbi Lonicera japonica Thunb.: ethnopharmacology, phytochemistry and pharmacology of an important traditional Chinese medicine
    Xiaofei Shang
    Engineering and Technology Center of Traditional Chinese Veterinary Medicine of Gansu, Key Laboratory of Veterinary Pharmaceutics Discovery, Ministry of Agriculture, Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Lanzhou 730050, PR China
    J Ethnopharmacol 138:1-21. 2011
    ..At the same time, Lonicera japonica could be used as healthy food, cosmetics, ornamental groundcover, and so on...
  64. pmc Medical ethnobotany of the Albanian Alps in Kosovo
    Behxhet Mustafa
    Department of Biology, University of Prishtina, Mother Teresa, Prishtine, Kosovo
    J Ethnobiol Ethnomed 8:6. 2012
    ....
  65. pmc Screening of anti-dengue activity in methanolic extracts of medicinal plants
    Leon I C Tang
    School of Medical Sciences, Faculty of Medicine and Health, International Medical University, Bukit Jalil, Kuala Lumpur, Malaysia
    BMC Complement Altern Med 12:3. 2012
    ..The development of a dengue vaccine is complicated by the antibody-dependent enhancement effect. Thus, the development of a plant-based antiviral preparation promises a more potential alternative in combating dengue disease...
  66. ncbi Use of complementary and alternative medicine among patients with chronic diseases at outpatient clinics
    Syed Shahzad Hasan
    School of Pharmacy, International Medical University, Bukit Jalil, 57000 Kuala Lumpur, Malaysia
    Complement Ther Clin Pract 15:152-7. 2009
    ..Another aim was to identify demographic and socio-economic factors that are associated with CAM use...
  67. pmc Botanical flavonoids on coronary heart disease
    Chong Zhi Wang
    Tang Center for Herbal Medicine Research and Departments of Anesthesia and Critical Care, The Pritzker School of Medicine, University of Chicago, Chicago, IL 60637, USA
    Am J Chin Med 39:661-71. 2011
    ..In this article, we will discuss two herbs containing potent flavonoids, Scutellaria baicalensis and grape seed proanthocyanidin, which can potentially offer cardiac protection against ischemic heart disease...
  68. pmc Cancer cell signaling pathways targeted by spice-derived nutraceuticals
    Bokyung Sung
    Cytokine Research Laboratory, Department of Experimental Therapeutics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Nutr Cancer 64:173-97. 2012
    ..Although they have always been used to improve taste and color and as a preservative, they are now also used for prevention and treatment of a wide variety of chronic inflammatory diseases, including cancer...
  69. ncbi Alternative therapies for the prevention and treatment of osteoporosis
    Jameela Banu
    Division of Clinical Immunology and Rheumatology, Department of Medicine, San Antonio, Texas, USA
    Nutr Rev 70:22-40. 2012
    ..The present review discusses the most promising findings from studies of these plant families...
  70. ncbi Herbal use among US elderly: 2002 National Health Interview Survey
    Jeffrey J Bruno
    Pharmacy Practice Resident, The Cleveland Clinic, Cleveland, OH, USA
    Ann Pharmacother 39:643-8. 2005
    ..The presence of polypharmacy and multiple comorbidities places the elderly at high risk for herb-drug and herb-disease interactions. Limited data exist regarding herbal use among the US elderly population...
  71. pmc The effects of barley-derived soluble fiber on serum lipids
    Ripple Talati
    University of Connecticut School of Pharmacy, Storrs, Connecticut, USA
    Ann Fam Med 7:157-63. 2009
    ..We wanted to determine the association between consumption of barley and changes in plasma lipids in healthy and hypercholesterolemic men and women...
  72. ncbi Medicinal plant knowledge and its erosion among the Mien (Yao) in northern Thailand
    Kamonnate Srithi
    Department of Biology, Faculty of Science, Chiang Mai University, Huaykaew Rd, Chiang Mai 50200, Thailand kamonnate
    J Ethnopharmacol 123:335-42. 2009
    ..We studied local knowledge and actual uses of medicinal plants among the Mien in northern Thailand, documenting traditional medical practices and its transfer between generations...
  73. ncbi Antimalarial activity of Bidens pilosa L. (Asteraceae) ethanol extracts from wild plants collected in various localities or plants cultivated in humus soil
    Valter F Andrade-Neto
    Laboratory of Malaria, Centro de Pesquisas Rene Rachou Fiocruz, Av Augusto de Lima 1715, Belo Horizonte, Minas Gerais CEP 30190 002, Brazil
    Phytother Res 18:634-9. 2004
    ....
  74. ncbi Cultural significance of medicinal plant families and species among Quechua farmers in Apillapampa, Bolivia
    Evert Thomas
    Laboratory of Tropical and Subtropical Agriculture and Ethnobotany, Ghent University, Coupure Links 653, B 9000 Ghent, Belgium
    J Ethnopharmacol 122:60-7. 2009
    ..Medicinal plant use was investigated in Apillapampa, a community of subsistence farmers located in the semi-arid Bolivian Andes...
  75. ncbi An antimicrobial investigation of plants used traditionally in southern Africa to treat sexually transmitted infections
    S F van Vuuren
    Department of Pharmacy and Pharmacology, Faculty of Health Sciences, University of Witwatersrand, Parktown, South Africa
    J Ethnopharmacol 130:552-8. 2010
    ..Eighteen plants were assessed for antimicrobial activity against pathogens associated with prevalent urogenital/sexually transmitted infections. Plant selection was based on information obtained from the ethnobotanical literature...
  76. ncbi Molecular aspects of phytoestrogen selective binding at estrogen receptors
    Joseph V Turner
    School of Medicine, Rural Clinical Division, The University of Queensland, Locked Bag 9009, Toowoomba DC, Brisbane, QLD 4350, Australia
    J Pharm Sci 96:1879-85. 2007
    ..This article explores the structural characteristics and significance of functional groups as they relate to phytoestrogen selectivity for ER binding...
  77. ncbi Role of selected Indian plants in management of type 2 diabetes: a review
    Abha Saxena
    Department of Medicine, All India Institute of Medical Sciences, New Delhi, India
    J Altern Complement Med 10:369-78. 2004
    ..Mechanisms such as the stimulating or regenerating effect on beta cells or extrapancreatic effects are proposed for the hypoglycemic action of these herbs...
  78. ncbi Traditional antimalarial phytotherapy remedies used by the Kwale community of the Kenyan Coast
    C N Muthaura
    Centre for Traditional Medicine and Drug Research, Kenya Medical Research Institute, PO Box 54840, Nairobi 00200, Kenya
    J Ethnopharmacol 114:377-86. 2007
    ..Three plant species, namely; Maytenus putterlickioides, Warburgia stuhlmannii and Pentas bussei are documented for the first time for the treatment of malaria...
  79. ncbi Anti-diabetic activity of green tea polyphenols and their role in reducing oxidative stress in experimental diabetes
    M C Sabu
    Amala Cancer Research Centre, Amala Nagar, Trichur 680 553, Kerala, India
    J Ethnopharmacol 83:109-16. 2002
    ..These results indicate that alterations in the glucose utilizing system and oxidation status in rats increased by alloxan were partially reversed by the administration of the glutamate pyruvate transaminase...
  80. ncbi The chemical composition of some Lauraceae essential oils and their antifungal activities
    A Simic
    Institute of Botany, Faculty of Biology, University of Belgrade, Serbia and Montenegro
    Phytother Res 18:713-7. 2004
    ..nobilis. In sassafras essential oil safrole was the major component and in the oil of C. zeylanicum the main component was trans-cinnamaldehyde. The essential oil of cinnamon showed the strongest antifungal activity...
  81. ncbi Antiplasmodial agents from the leaves of Glossocalyx brevipes
    James A Mbah
    Chemistry Department, Faculty of Science, University of Dschang, Dschang, Cameroon
    Planta Med 70:437-40. 2004
    ..Compounds 1 and 2 and liriodenine showed modest in vitro activity against Plasmodium falciparum...
  82. ncbi Renal effects of plant-derived oleanolic acid in streptozotocin-induced diabetic rats
    R F Mapanga
    Disciplines of Human Physiology, Faculty of Health Sciences, University of KwaZulu Natal, Westville Campus, Private Bag X54001, Durban, South Africa
    Ren Fail 31:481-91. 2009
    ..OA also caused significant decreases in MAP in non-diabetic and STZ-induced diabetic rats. These findings suggest that OA may have beneficial effects on some processes associated with renal derangement of STZ-induced diabetic rats...
  83. ncbi A systematic review of the effectiveness of Chinese herbal medication in symptom management and improvement of quality of life in adult cancer patients
    A Molassiotis
    School of Nursing, Midwifery and Social Work, University of Manchester, University Place, Manchester M13 9PL, UK
    Complement Ther Med 17:92-120. 2009
    ..However, more methodologically rigorous studies need to be developed as a priority before any firm conclusions can be drawn...
  84. ncbi Goji (Lycium barbarum and L. chinense): Phytochemistry, pharmacology and safety in the perspective of traditional uses and recent popularity
    Olivier Potterat
    Department of Pharmaceutical Sciences, Division of Pharmaceutical Biology, University of Basel, Basel, Switzerland
    Planta Med 76:7-19. 2010
    ..barbarum and L. chinense certainly deserve further investigation. However, clinical evidences and rigorous procedures for quality control are indispensable before any recommendation of use can be made for Goji products...
  85. pmc An ethnobotanical study of medicinal plants in Wonago Woreda, SNNPR, Ethiopia
    Fisseha Mesfin
    Biology Department, Addis Ababa University, Addis Ababa, Ethiopia
    J Ethnobiol Ethnomed 5:28. 2009
    ..Hence, the aim of this study is to document the medicinal plants in the natural vegetation and home gardens in Wonago Woreda, Gedeo Zone, Southern Nations, Nationalities and Peoples Regional State (SNNPR)...
  86. ncbi An in vitro study on antiproliferative and antiestrogenic effects of Boerhaavia diffusa L. extracts
    Sreekumar Sreeja
    Cancer Endocrinology, Integrated Cancer Research Programme, Rajiv Gandhi Centre for Biotechnology, Thycaud P O, Thiruvananthapuram, Kerala 695014, India
    J Ethnopharmacol 126:221-5. 2009
    ..This plant also has antilymphoproliferative, antimetastatic and immunomodulatory effects...
  87. pmc Apoptosis by dietary agents for prevention and treatment of prostate cancer
    Naghma Khan
    Department of Dermatology, Medical Sciences Center, University of Wisconsin Madison, 4385, 1300 University Avenue, Madison, Wisconsin 53706, USA
    Endocr Relat Cancer 17:R39-52. 2010
    ..In this article, we highlight the studies of various apoptosis-inducing dietary compounds for prevention of PCa in vitro in cell culture, in preclinical studies in animals, and in human clinical trials...
  88. ncbi Ethnomedicines used against four common ailments by the tribal communities of Lahaul-Spiti in western Himalaya
    K N Singh
    Biodiversity Division, Institute of Himalayan Bioresource Technology, Palampur, 176061 Himachal Pradesh, India
    J Ethnopharmacol 115:147-59. 2008
    ..Mode of preparation, administration and dosage are discussed along with the family and local names of plants and plant parts used...
  89. ncbi A randomized controlled pilot trial of "Feiji Recipe" on quality of life of non-small cell lung cancer patients
    Jian Hui Tian
    Department of Oncology, Shanghai Municipal Clinical Medical, Centre for Traditional Chinese Oncology, China
    Am J Chin Med 38:15-25. 2010
    ..No unexpected side effects were observed. However, further double-blinded placebo controlled studies are strongly recommended...
  90. pmc Ethnobotanical study of indigenous knowledge on medicinal plant use by traditional healers in Oshikoto region, Namibia
    Ahmad Cheikhyoussef
    Science, Technology and Innovation Division, Multidisciplinary Research Centre University of Namibia, Private Bag 13301, Windhoek, Namibia
    J Ethnobiol Ethnomed 7:10. 2011
    ....
  91. ncbi Aqueous extract of Rhodiola imbricata rhizome stimulates proinflammatory mediators via phosphorylated IkappaB and transcription factor nuclear factor-kappaB
    K P Mishra
    Defence Institute of Physiology and Allied Sciences, Lucknow Road, Timarpur, Delhi, India
    Immunopharmacol Immunotoxicol 28:201-12. 2006
    ..Our study demonstrates immunostimulatory potential of aqueous extract of Rhodiola rhizome, that can be used for upregulation of immune response in patients with inadequate functioning of the immune system...
  92. ncbi Ethnobotany of plants used by the Thari people of Nara Desert, Pakistan
    Rahmatullah Qureshi
    Pir Mehr Ali Shah Arid Agriculture University, Department of Botany, Murree Road, Rawalpindi Pakistan
    Fitoterapia 79:468-73. 2008
    ..About 44 types of ailments were treated with various parts of the 51 medicinal plant species. For treating ailments, the use of the whole plant was higher (53%) than leaves (18%), roots (14%) and fruits (10%) alone...
  93. pmc Use of medicinal plants for human health in Udzungwa Mountains Forests: a case study of New Dabaga Ulongambi Forest Reserve, Tanzania
    Rukia A Kitula
    Department of Wood Utilization, Sokoine University of Agriculture, Morogoro, Tanzania
    J Ethnobiol Ethnomed 3:7. 2007
    ..During the development of a joint draft management plan, villagers as an informal institution must define their priority needs of use of parts of the forest in collaboration with the Udzungwa Mountains Forest Management project...
  94. ncbi Advances in cancer therapy with plant based natural products
    A K Mukherjee
    Chembiotek Research International, Salt Lake, Calcutta, 700091, India
    Curr Med Chem 8:1467-86. 2001
    ..The review also deals with the lesser-known plants of sub-Himalayan region...
  95. ncbi Trigonella foenum graecum seed powder protects against histopathological abnormalities in tissues of diabetic rats
    Shalini Thakran
    Hormone and Drug Research Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi, India
    Mol Cell Biochem 266:151-9. 2004
    ..The role of TSP in reversing the diabetic state at the cellular level besides the metabolic normalization further proves its potential as an antidiabetic agent...
  96. ncbi Natural health product-drug interactions: a systematic review of clinical trials
    Edward Mills
    Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada
    Ther Drug Monit 27:549-57. 2005
    ..With the exception of St. John wort, clinicians and the public do not have information that permits strong inferences about interactions between NHPs and conventional medications...
  97. ncbi Gastroprotective activity of Pradosia huberi on experimentally induced gastric lesions in rodents: role of endogenous sulphydryls and nitric oxide
    Hélio Kushima
    Departamento de Fisiologia, Instituto de Biociencias, Universidade Estadual Paulista UNESP, Botucatu, CP 510, CEP 18608 000, Botucatu, Sao Paulo, Brazil
    J Ethnopharmacol 101:61-7. 2005
    ..01). The mechanism of action of HAE did not seem to be related to the NO-inhibitor but showed the participation of endogenous sulphydryl group in the gastroprotective action...
  98. ncbi Passionflower in the treatment of generalized anxiety: a pilot double-blind randomized controlled trial with oxazepam
    S Akhondzadeh
    Roozbeh Psychiatric Hospital, Tehran University of Medical Sciences, South Kargar Avenue, Tehran, Iran
    J Clin Pharm Ther 26:363-7. 2001
    ..Passionflower (Passiflora incarnata) is a folk remedy for anxiety. A double-blind randomized trial compared the efficacy of Passiflora incarnata extract with oxazepam in the treatment of generalized anxiety disorder...
  99. pmc Antidiabetic and renoprotective effects of the chloroform extract of Terminalia chebula Retz. seeds in streptozotocin-induced diabetic rats
    Nalamolu Koteswara Rao
    Pharmacology Division, GITAM Dental College, Visakhapatnam 530045, Andhra Pradesh, India
    BMC Complement Altern Med 6:17. 2006
    ..The efficacy of the extract was also evaluated for protection of renal functions in diabetic rats...
  100. ncbi Oleanolic acid, a natural triterpenoid improves blood glucose tolerance in normal mice and ameliorates visceral obesity in mice fed a high-fat diet
    Célio L de Melo
    Department of Clinical and Toxicological Analysis, Federal University of Ceara, Fortaleza, Ceara, Brazil
    Chem Biol Interact 185:59-65. 2010
    ..These findings suggest that OA ameliorates visceral adiposity and improves glucose tolerance in mice and thus has an antiobese potential through modulation of carbohydrate and fat metabolism...
  101. ncbi Anti-HBV active flavone glucosides from Euphorbia humifusa Willd
    Ying Tian
    Department of Pharmaceutical Chemistry, Beijing Institute of Radiation Medicine, Beijing 100850, PR China
    Fitoterapia 81:799-802. 2010
    ..In addition, the substitution of acyl group on glucoside may be important to keep the anti-HBV activities of these compounds (galloyl>feruloyl>coumaroyl)...

Research Grants58

  1. Complementary and Alternative Medicine for Urological Symptoms (CAMUS)
    Andrew L Avins; Fiscal Year: 2010
    ....
  2. Center for Chinese Herbal Therapy (CHT) for Asthma
    Xiu Min Li; Fiscal Year: 2009
    ....
  3. Effect of Chinese herbal medicine on food allergy
    Xiu Min Li; Fiscal Year: 2010
    ....
  4. Immunological response to Chinese herbal medicine in food allergy
    Julie Wang; Fiscal Year: 2013
    ..This potential therapy has significant advantages over other treatments currently under investigation because it is administered orally, has a high safety profile, and may provide long-term protection from anaphylaxis...
  5. Alternative Therapies for Benign Prostate Symptoms
    Karl J Kreder; Fiscal Year: 2011
    ..The purpose of this consortium is to study the effect of phytotherapy using Sernoa repens (saw palmetto) and Pygeum africanum in men with benign prostatic hyperplasia (BPH)...
  6. Alternative Therapies for Benign Prostate Symptoms
    Andrew R McCullough; Fiscal Year: 2010
    ..The phytotherapy serenoa repens is being studied in this trial and its effectiveness will be compared to placebo...
  7. Saw palmetto and Pygeum africanum on BPH Progression
    Kevin T McVary; Fiscal Year: 2010
    ..Increasing attention has been paid to plant extracts (or phytotherapy) use by patients to self-treat medical ailments such as BPH...
  8. TICIPS: HIV/AIDS, Secondary Infections and Immune Modul*
    WILLIAM ROBERT FOLK; Fiscal Year: 2010
    ..It is essential to document that this widely used phytotherapy can be used safely in HIV-infected adults, and to attempt to demonstrate potentially beneficial affects...
  9. CAMUS-Complimentary and Alternative Medicine for Urological Symptoms
    Harris E Foster; Fiscal Year: 2010
    ..The use of phytotherapy to relieve lower urinary tract symptoms, particularly BPH, has spurred interest in Serenoa repens (Saw palmetto)..
  10. Phytotherapy of Prostateic Symptoms (POPW)
    E David Crawford; Fiscal Year: 2010
    ..CDS) funded 11 clinical centers and a coordinating site for seven years from 2002 -2009 to investigate phytotherapy for benign prostatic hyperplasia (BPH)...
  11. Int'l Center for Indigenous Phytotherapy Studies--TICIPS
    William Folk; Fiscal Year: 2004
    The University of Missouri-Columbia (MU) will form the International Center for Indigenous Phytotherapy Studies (TICIPS) in collaboration with the University of Western Cape, South Africa (UWC) and the Missouri Botanical Garden, St...
  12. Herbal Therapy and Neuroprotection in Cerebral Ischemia
    Baowan Lin; Fiscal Year: 2005
    ..We shall make extensive use of quantitative histopathology, image-analysis, and immunohistochemistry of COX2, iNOS, A-beta, beta-APP and multiple markers of neuronal, glial, and endothelial integrity or injury. ..
  13. Controlled Trial of an Herbal Therapy for ADHD
    Wendy Weber; Fiscal Year: 2006
    ..abstract_text> ..
  14. KAVA KAVA IN GENERALIZED ANXIETY: A DOUBLE-BLIND TRIAL
    Jonathan Davidson; Fiscal Year: 2001
    ..With public interest in phytotherapy for depression and anxiety now on the rise in the US, we propose to evaluate KAV in generalized anxiety ..
  15. A Botanical Drug for Social Phobia
    Ronald Goldblum; Fiscal Year: 2001
    ..Additionally, increasing attention has been given to the poor formulation/standardization of current botanical dietary supplements. An FDA approved phytotherapy for social phobia will likely enjoy significant commercial success.
  16. Magnesium and Asthma - Clinical Trials
    Judith Stern; Fiscal Year: 2004
    ..We do not anticipate that Mg supplementation will replace conventional treatment, but may complement and decrease the need for conventional medications. ..
  17. OBESE FEMALE RESTRAINED EATERS : TWO TREATMENT OPTIONS
    Judith Stern; Fiscal Year: 2002
    ..A manual of procedures will be generated to assist others in replicating the intervention. ..
  18. Acupuncture to aid post-colectomy recovery in colorectal cancer patients
    Gary Deng; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  19. Effects of Amino Acid Therapy on Hot Flashes in Postmenopausal Women
    Thomas Guttuso; Fiscal Year: 2007
    ..The applicant will also attend two didactic training seminars in complementary & alternative medicine at The Osher Institute at Harvard Medical School and at the Duke Center for Integrative Medicine. ..
  20. CAM Approaches to Air Pollution Related Health Effects
    Jason Allen; Fiscal Year: 2007
    ..The long-term objective of this research is to rigorously examine potential CAM interventions in augmenting adverse health effects induced by pollutants that pose a substantial ongoing public health burden. ..
  21. Osteoporotic fractures in Chinese men: MrOs Hong Kong
    PING LEUNG; Fiscal Year: 2007
    ..abstract_text> ..
  22. MECHANISMS OF CADMIUM TOXICITY IN EPITHELIAL CELLS
    WALTER PROZIALECK; Fiscal Year: 2007
    ..Furthermore, the results of these studies could have more general implications regarding the mechanisms by which toxic substances affect living organisms. ..
  23. Clinical Trial Development in Chronic Pelvic Pain Syndr*
    Daniel Shoskes; Fiscal Year: 2007
    ..in erectile dysfunction, rectal dysfunction, chronic pain management, complementary therapies (acupuncture, phytotherapy) and neuropsychology...
  24. Mechanisms of Neutrophil-induced Liver Toxicity
    Hartmut Jaeschke; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  25. Plants in the service of human health
    DJAJA SOEJARTO; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
  26. Dietary Factors in the Etiology of Colorectal Cancer
    Jian Min Yuan; Fiscal Year: 2008
    ..The potential modifying effects of HAA activating genes and tea polyphenols on the HAA-colorectal cancer association will be explored. [unreadable] [unreadable]..
  27. Mitochondrial Dysfunction and Drug Hepatotoxicity
    HARTMUT W JAESCHKE; Fiscal Year: 2010
    ..This new insight into the signaling mechanism of AAP-induced cell death holds the promise of establishing novel therapeutic approaches for preventing AAP-induced liver failure and potentially other forms of drug toxicity in humans. ..
  28. The Enigma of Placebo Adherence and Health Outcomes
    Andrew Avins; Fiscal Year: 2009
    ..The results of this investigation will shed important light on powerful biomedical and non-biomedical determinants of health outcomes that, at present, are insufficiently documented and poorly understood. ..
  29. Tea Polyphenols in Chemoprevention of Prostate Cancer
    SUSANNE MARGARETE HENNING; Fiscal Year: 2011
    ..The results will assist in designing dietary supplements for chemoprevention of early stages of prostate cancer or during watchful waiting. ..
  30. THE SINGAPORE COHORT STUDY OF DIET AND CANCER
    Jian Min Yuan; Fiscal Year: 2009
    ....
  31. Reactivation Methylation-Silenced Genes by Polyphenols
    Chung Yang; Fiscal Year: 2007
    ..5. To determine whether EGCG, alone or in combination with other agents, can prevent hypermethylation of genes and tumor development in the intestinal tumorigenesis model in the Min mice. ..
  32. Patterns and correlates of CAM use in African Americans
    Carolyn Brown; Fiscal Year: 2007
    ..Long-term objectives are to enhance the provision and effectiveness of health care interventions in African American populations and to generate research questions for future investigations of CAM use in African Americans. [unreadable]..
  33. CLUSTERIN--AN ANTI APOPTOTIC MEDIATOR IN PROSTATE CANCER
    Chung Lee; Fiscal Year: 2004
    ..Expression constructs will be used to regulate clusterin expression, which will be correlated with the status of tumor progression. ..
  34. Conspiracies, Perceived Discrimination & Sexual Behavior
    Sheryl Thorburn; Fiscal Year: 2003
    ..Findings from this study will inform efforts to prevent HIV and other STDs, as well as unintended pregnancy, among African Americans nationally. ..
  35. Pilot Study of Huperzine A in Alzheimer's Disease
    Paul Aisen; Fiscal Year: 2003
    ....
  36. MOLECULAR REGULATION OF THE HUMAN BRCA 1 GENE
    DONATO ROMAGNOLO; Fiscal Year: 2003
    ..Specific aim #3 will examine the function of BRCA-1 in cell cycle regulation at different levels of genotoxic damage induced by PAHs. ..
  37. Bioavailability of Tea Polyphenols in Prostate Cancer
    Susanne Henning; Fiscal Year: 2002
    ..ODC enzyme activity will be determined measuring the release of 14C CO2 from 14C ornithine. These studies will provide information important in designing studies to critically test the role of dietary supplementation in prostate cancer. ..
  38. PROSTATIC DUCTAL SYSTEM--CELL TO CELL INTERACTION
    Chung Lee; Fiscal Year: 2002
    ..We propose to use a dominant negative type II TGF-beta receptor (TbetaRII-DN) expression vector to render cells insensitive to TGF-beta. We also will study the prostate of TGF-beta1 knockout mice. ..
  39. A RANDOMIZED CONTROLLED TRIAL OF ECHINACEA IN CHILDREN
    James Taylor; Fiscal Year: 2001
    ..abstract_text> ..
  40. PROSTATE CANCER SCREENING & MORTALITY: SEATTLE VS. CT.
    Michael Barry; Fiscal Year: 2004
    ....
  41. SAW PALMETTO EXTRACT IN BENIGN PROSTATIC HYPERPLASIA
    Andrew Avins; Fiscal Year: 2003
    ..Numerous laboratory parameters will measured at intervals throughout the trial and symptomatic side effects will be assessed. ..
  42. JHU-NUS Center for Research on CAMs(Planning Grant)
    PAUL LIETMAN; Fiscal Year: 2004
    ..abstract_text> ..
  43. Use of Curcumin and Flaxsseed in Radiation Pneumonopathy
    Melpo Christofidou Solomidou; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  44. Breast Cancer Screening and Follow-up in a PBRN: The Ma*
    Michael Barry; Fiscal Year: 2007
    ..We will create a process to track all patients within our PBRN and to reduce current barriers to ordering and following up of abnormal mammogram results. [unreadable] [unreadable]..
  45. ESOPHAGEAL ADENOCARCINOGENESIS AND ITS PREVENTION
    Chung Yang; Fiscal Year: 2007
    ..These studies are expected to fully elucidate the roles of oxidative stress and aberrant AA metabolism in the formation of EAC and help develop effective agents for its prevention. ..
  46. CALCIUM METABOLISM IN ASIAN GIRLS AND POSTMENOPAUSAL WOMEN
    Connie Weaver; Fiscal Year: 2006
    ..Optimizing calcium retention during periods of rapid growth is a key nutritional strategy to build peak bone mass and reduce lifelong risk of osteoporosis. ..
  47. DIETARY FACTORS IN THE ETIOLOGY OF CANCER IN SHANGHAI
    Jian Min Yuan; Fiscal Year: 2006
    ..In all instances of diet-cancer investigations, relevant genes with potential modifying effects on the respective diet-cancer associations will be included in the investigations. ..
  48. Calcium, Dairy, and Body Fat in Adolescents
    Connie Weaver; Fiscal Year: 2006
    ..This study will evaluate calcium/dairy as a modulator of energy balance, important to the management of body fat in children. ..
  49. The Feasibility of Assessing the Prevalence of Rickets
    James Taylor; Fiscal Year: 2006
    ..In addition to assessing possible methodologies for the larger project, the preliminary study is designed to yield standalone results with important implications. [unreadable] [unreadable] [unreadable]..
  50. INHIBITION OF CARCINOGENESIS BY TEA AND TEA CONSTITUENTS
    Chung Yang; Fiscal Year: 2005
    ..Jointly, we intend to make major contributions to the use of tea for the I chemoprevention of cancer. ..
  51. Tumor reactive, TGF-Beta insensitive T cells against ca.
    Chung Lee; Fiscal Year: 2005
    ..abstract_text> ..
  52. MECHANISTIC STUDIES ON TEA AND CARCINOGENESIS
    Chung Yang; Fiscal Year: 2005
    ..The applicant and colleagues will address key issues concerning the bioavailability and bioactivities of O-methyl, glucuronide, and sulfate derivatives and two ring-fission metabolites of tea catechins. ..
  53. 24,25-DIHYDROXYVITAMIN D: MARKER OF SALT SENSITIVITY
    Connie Weaver; Fiscal Year: 2001
    ..Furthermore, they should provide an explanation for the paradox that blacks can build higher bone density, have a lower rate of bone turnover, and excrete less urinary calcium on the same sodium loads compared to whites. ..