complementary therapies

Summary

Summary: Therapeutic practices which are not currently considered an integral part of conventional allopathic medical practice. They may lack biomedical explanations but as they become better researched some (PHYSICAL THERAPY; DIET; ACUPUNCTURE) become widely accepted whereas others (humors, radium therapy) quietly fade away, yet are important historical footnotes. Therapies are termed as Complementary when used in addition to conventional treatments and as Alternative when used instead of conventional treatment.

Top Publications

  1. ncbi Use of complementary and alternative medicine in cancer patients: a European survey
    A Molassiotis
    School of Nursing, University of Manchester, Manchester, UK
    Ann Oncol 16:655-63. 2005
  2. doi Trends in the use of complementary and alternative medicine in the United States: 2002-2007
    Dejun Su
    Department of Sociology, South Texas Border Health Disparities Center, University of Texas Pan American, Edinburg, TX 78541, USA
    J Health Care Poor Underserved 22:296-310. 2011
  3. ncbi Complementary and alternative medicine use in Australia: a national population-based survey
    Charlie C L Xue
    World Health Organization Collaborating Centre for Traditional Medicine, School of Health Sciences, Melbourne, Melbourne, Australia
    J Altern Complement Med 13:643-50. 2007
  4. ncbi Use and expenditure on complementary medicine in England: a population based survey
    K J Thomas
    Medical Centre Research Unit, School of Health and Related Research, University of Sheffield, Sheffield, UK
    Complement Ther Med 9:2-11. 2001
  5. pmc Complementary and alternative medicine use in oncology: a questionnaire survey of patients and health care professionals
    Kah Hoong Chang
    Department of Surgery, University College Hospital Galway, National University of Ireland
    BMC Cancer 11:196. 2011
  6. doi How many cancer patients use complementary and alternative medicine: a systematic review and metaanalysis
    Markus Horneber
    Department of Internal Medicine, Division ofOncology Hematology, Klinikum Nuernberg, Nuernberg, Germany
    Integr Cancer Ther 11:187-203. 2012
  7. ncbi Use of complementary therapies in patients with cardiovascular disease
    Gloria Y Yeh
    Division for Research and Education in Complementary and Integrative Medical Therapies, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 98:673-80. 2006
  8. pmc Development and classification of an operational definition of complementary and alternative medicine for the Cochrane collaboration
    L Susan Wieland
    Center for Integrative Medicine, University of Maryland School of Medicine, Baltimore, USA
    Altern Ther Health Med 17:50-9. 2011
  9. ncbi The continuing use of complementary and alternative medicine in South Australia: costs and beliefs in 2004
    Alastair H MacLennan
    Department of Obstetrics and Gynaecology, University of Adelaide, Women s and Children s Hospital, 72 King William Road, North Adelaide, SA 5006, Australia
    Med J Aust 184:27-31. 2006
  10. pmc The use of complementary and alternative fertility treatment in couples seeking fertility care: data from a prospective cohort in the United States
    James F Smith
    Department of Urology, University of California, San Francisco, California 94143 1695, USA
    Fertil Steril 93:2169-74. 2010

Detail Information

Publications392 found, 100 shown here

  1. ncbi Use of complementary and alternative medicine in cancer patients: a European survey
    A Molassiotis
    School of Nursing, University of Manchester, Manchester, UK
    Ann Oncol 16:655-63. 2005
    ..The aim of this study was to explore the use of complementary and alternative medicine (CAM) in cancer patients across a number of European countries...
  2. doi Trends in the use of complementary and alternative medicine in the United States: 2002-2007
    Dejun Su
    Department of Sociology, South Texas Border Health Disparities Center, University of Texas Pan American, Edinburg, TX 78541, USA
    J Health Care Poor Underserved 22:296-310. 2011
    ..In both 2002 and 2007, having unmet needs in medical care or having delayed care due to cost were associated with a higher chance of CAM use...
  3. ncbi Complementary and alternative medicine use in Australia: a national population-based survey
    Charlie C L Xue
    World Health Organization Collaborating Centre for Traditional Medicine, School of Health Sciences, Melbourne, Melbourne, Australia
    J Altern Complement Med 13:643-50. 2007
    ....
  4. ncbi Use and expenditure on complementary medicine in England: a population based survey
    K J Thomas
    Medical Centre Research Unit, School of Health and Related Research, University of Sheffield, Sheffield, UK
    Complement Ther Med 9:2-11. 2001
    ..Estimates of practitioner visits in the USA and Australia indicate high levels of use and expenditure. No reliable population-based estimates of practitioner use are available for the UK...
  5. pmc Complementary and alternative medicine use in oncology: a questionnaire survey of patients and health care professionals
    Kah Hoong Chang
    Department of Surgery, University College Hospital Galway, National University of Ireland
    BMC Cancer 11:196. 2011
    ....
  6. doi How many cancer patients use complementary and alternative medicine: a systematic review and metaanalysis
    Markus Horneber
    Department of Internal Medicine, Division ofOncology Hematology, Klinikum Nuernberg, Nuernberg, Germany
    Integr Cancer Ther 11:187-203. 2012
    ..No comprehensive systematic review has been published since 1998 about the frequency with which cancer patients use complementary and alternative medicine (CAM)...
  7. ncbi Use of complementary therapies in patients with cardiovascular disease
    Gloria Y Yeh
    Division for Research and Education in Complementary and Integrative Medical Therapies, Harvard Medical School, Boston, Massachusetts, USA
    Am J Cardiol 98:673-80. 2006
    ..CAM use specifically to treat cardiovascular conditions, however, is less common...
  8. pmc Development and classification of an operational definition of complementary and alternative medicine for the Cochrane collaboration
    L Susan Wieland
    Center for Integrative Medicine, University of Maryland School of Medicine, Baltimore, USA
    Altern Ther Health Med 17:50-9. 2011
    ..Although aspects of our operational definition of CAM are open to revision, a standardized definition provides us with an objective, reproducible, and systematic method for defining and classifying CAM therapies...
  9. ncbi The continuing use of complementary and alternative medicine in South Australia: costs and beliefs in 2004
    Alastair H MacLennan
    Department of Obstetrics and Gynaecology, University of Adelaide, Women s and Children s Hospital, 72 King William Road, North Adelaide, SA 5006, Australia
    Med J Aust 184:27-31. 2006
    ..To survey the use, cost, beliefs and quality of life of users of complementary and alternative medicine (CAM)...
  10. pmc The use of complementary and alternative fertility treatment in couples seeking fertility care: data from a prospective cohort in the United States
    James F Smith
    Department of Urology, University of California, San Francisco, California 94143 1695, USA
    Fertil Steril 93:2169-74. 2010
    ..To determine the prevalence of complementary and alternative medicine (CAM) use among couples seeking fertility care and to identify the predictors of CAM use in this population...
  11. ncbi Changing boundaries: modes of coexistence of alternative and biomedicine
    Judith T Shuval
    Hebrew University of Jerusalem, Israel
    Qual Health Res 14:675-90. 2004
    ..The authors used decoupling theory in interpreting the findings. Changed boundary contours signal underlying processes of social change that could have meaningful implications in defining membership criteria in the biomedical community...
  12. doi Complementary alternative medicine (CAM) use in Ireland: a secondary analysis of SLAN data
    Patricia Fox
    UCD School of Nursing, Midwifery and Health Systems, Health Sciences Centre, University College Dublin, Belfield, Dublin 4, Ireland
    Complement Ther Med 18:95-103. 2010
    ..The aim of this study was to estimate the prevalence of CAM use among the general population in Ireland and to identify characteristics of typical Irish CAM users...
  13. pmc Prevalence of use of complementary/alternative medicine: a systematic review
    E Ernst
    Department of Complementary Medicine, Postgraduate Medical School, University of Exeter, England
    Bull World Health Organ 78:252-7. 2000
    ..The true prevalence of use of complementary/alternative medicine in the general population remains uncertain...
  14. ncbi Nationwide survey on complementary and alternative medicine in cancer patients in Japan
    Ichinosuke Hyodo
    Medical Oncology Division, National Shikoku Cancer Center, Horinouchi 13, Matsuyama, 790 0007 Ehime, Japan
    J Clin Oncol 23:2645-54. 2005
    ..To determine the prevalence of use of complementary and alternative medicine (CAM) by patients with cancer in Japan, and to compare the characteristics of CAM users and CAM nonusers...
  15. pmc Patterns of complementary and alternative medicine use amongst outpatients in Tokyo, Japan
    Satoshi Hori
    Department of Urology, West Suffolk Hospital, Bury St, Edmunds, UK
    BMC Complement Altern Med 8:14. 2008
    ....
  16. ncbi Disclosure of CAM use to medical practitioners: a review of qualitative and quantitative studies
    A Robinson
    Monash University School of Rural Health, P O Box 424, Traralgon, VIC 3844, Australia
    Complement Ther Med 12:90-8. 2004
    ..This literature review aims to provide an understanding of the degree to which patients disclose their use of CAM to their medical practitioners, and their reasons for not doing so...
  17. pmc From parallel practice to integrative health care: a conceptual framework
    Heather Boon
    Leslie Dan Faculty of Pharmacy, University of Toronto, ON, M5S 2S2, Canada
    BMC Health Serv Res 4:15. 2004
    ..The purpose of this paper is to develop a conceptual framework for describing, comparing and evaluating different forms of team-oriented health care practices that have evolved in Western health care systems...
  18. ncbi Use of complementary and alternative medicine in the Scandinavian countries
    Borghild Hanssen
    National Research Centre in Complementary and Alternative Medicine, University of Tromsø, Norway
    Scand J Prim Health Care 23:57-62. 2005
    ..To describe the prevalence of use of complementary and alternative medicine (CAM) in Norway, Denmark and Stockholm County...
  19. ncbi Complementary therapies: have they become accepted in general practice?
    M V Pirotta
    Department of General Practice and Public Health, University of Melbourne, Carlton, Vic
    Med J Aust 172:105-9. 2000
    To describe Victorian general practitioners' attitudes towards and use of a range of complementary therapies.
  20. doi Use of complementary and alternative medicine among patients with chronic diseases at outpatient clinics
    Syed Shahzad Hasan
    School of Pharmacy, International Medical University, Bukit Jalil, 57000 Kuala Lumpur, Malaysia
    Complement Ther Clin Pract 15:152-7. 2009
    ..Another aim was to identify demographic and socio-economic factors that are associated with CAM use...
  21. ncbi A national census of medicines use: a 24-hour snapshot of Australians aged 50 years and older
    Tessa K Morgan
    National Prescribing Service, Sydney, NSW
    Med J Aust 196:50-3. 2012
    ..To explore the current use of conventional and complementary medicines in Australians aged ≥ 50 years...
  22. doi Use of complementary and alternative medicine by patients with inflammatory bowel disease
    Robert J Hilsden
    Department of Community Health Sciences, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    Inflamm Bowel Dis 17:655-62. 2011
    ..It is important for physicians caring for those with IBD to be familiar with common forms of CAM and to be able to provide general counseling to their patients about CAM use...
  23. doi Great expectations: what do patients using complementary and alternative medicine hope for?
    E Ernst
    Complementary Medicine, Peninsula Medical School, University of Exeter, Exeter, UK
    Patient 4:89-101. 2011
    ..It is concluded that the expectations of CAM users are currently not rigorously investigated. Future studies should have a clear focus on specific aspects of this broad question...
  24. doi Complementary therapies for neuropathic and neuralgic pain: systematic review
    Max H Pittler
    Complementary Medicine, Peninsula Medical School, Universities of Exeter and Plymouth, Exeter, UK
    Clin J Pain 24:731-3. 2008
    ..To assess the evidence from rigorous clinical trials, systematic reviews, and meta-analyses of complementary and alternative therapies for treating neuropathic and neuralgic pain...
  25. ncbi Use of complementary and alternative therapies in HIV-infected patients
    J Duggan
    Department of Physiology and Molecular Medicine, Medical College of Ohio, Toledo, Ohio 43614 5804, USA
    AIDS Patient Care STDS 15:159-67. 2001
    ..Use of CAM remains widespread among patients with HIV infection even with the availability of effective, yet noncurative antiretroviral therapy and does not correlate with type of antiretroviral therapy used or clinical status...
  26. ncbi Use of complementary and alternative medicine among people living with diabetes: literature review
    Hsiao yun Chang
    School of Nursing and Midwifery, Griffith University, Gold Coast, Queensland, Australia
    J Adv Nurs 58:307-19. 2007
    ..This paper is a report of a literature review to explore the prevalence of complementary and alternative medicine use amongst people with diabetes to inform nursing practice, education and research...
  27. ncbi Self-care dimensions of complementary and alternative medicine use among older adults
    Kristine Votova
    Department of Sociology, University of Victoria, Victoria, Canada
    Gerontology 53:21-7. 2007
    ..There is a lack of understanding about the patterns and rates of CAM use among older adults owing to a lack of research on specific types of CAM...
  28. ncbi Complementary medicine in general practice - a national survey of GP attitudes and knowledge
    Marie Pirotta
    Department of General Practice and Primary Health Care Academic Centre, University of Melbourne, Victoria
    Aust Fam Physician 39:946-50. 2010
    ..This article compares the demographics of Australian general practitioners who do, and those who do not, practise integrative medicine, and their perceptions and knowledge about complementary medicines...
  29. doi Current alternative and complementary therapies used in menopause
    Veronica Chi Ken Wong
    Department of Obstetrics and Gynaecology, Liverpool Hospital, Faculty of Medicine, University of New South Wales, Sydney, Australia
    Gynecol Endocrinol 25:166-74. 2009
    ..To determine the efficacy and safety of common complementary and alternative medicine (CAM) therapies used to relieve the menopausal symptoms...
  30. ncbi Complementary therapies for reducing body weight: a systematic review
    M H Pittler
    Complementary Medicine, Peninsula Medical School, Universities of Exeter and Plymouth, UK
    Int J Obes (Lond) 29:1030-8. 2005
    The prevalence of obesity is increasing at an alarming rate and a plethora of complementary therapies are on offer claiming effectiveness for reducing body weight...
  31. ncbi Popularity of complementary and alternative medicine in Japan: a telephone survey
    H Yamashita
    Tsukuba College of Technology Clinic, Tsukuba, Japan
    Complement Ther Med 10:84-93. 2002
    ..To obtain information on the use of complementary and alternative medicine (CAM) in Japan...
  32. pmc Complementary therapies for children undergoing stem cell transplantation: report of a multisite trial
    Sean Phipps
    Department of Behavioral Medicine, St Jude Children s Research Hospital, Memphis, Tennessee 38105 3678, USA
    Cancer 116:3924-33. 2010
    ..This trial evaluated the efficacy of complementary therapies (massage, humor therapy, relaxation/imagery) for reducing distress associated with pediatric SCT.
  33. doi Integrative medicine models in contemporary primary health care
    Kate Templeman
    Monash University, Faculty of Medicine, Nursing and Health Sciences, School of Rural Health, Department of Rural and Indigenous Health, Australia
    Complement Ther Med 19:84-92. 2011
    ....
  34. doi Complementary and alternative medicine use in children with cancer and general and specialty pediatrics
    Janice Post-White
    University of Minnesota, Minneapolis, MN 55403, USA postw001 umn edu
    J Pediatr Oncol Nurs 26:7-15. 2009
    ..Children with cancer use CAM for different reasons than children with non-life-threatening illnesses...
  35. ncbi On the definition of complementary, alternative, and integrative medicine: societal mega-stereotypes vs. the patients' perspectives
    Opher Caspi
    Program in Integrative Medicine, University of Arizona, Tucson, Arizona, USA
    Altern Ther Health Med 9:58-62. 2003
    ..It is our conclusion that individual patients, rather than society, should be the frame of reference and defining source for what constitutes integrative medicine and CAM...
  36. doi High use of complementary and alternative medicine inside and outside of the government-funded health care system in Norway
    Vinjar Fønnebø
    National Research Center in Complementary and Alternative Medicine, University of Tromsø, Tromsø, Norway
    J Altern Complement Med 15:1061-6. 2009
    ..The objective of this study was to describe the Norwegian population's use of complementary and alternative medicine (CAM) inside as well as outside of the health care system in Norway over the previous 12 months...
  37. ncbi Use of complementary and alternative medical therapies in patients with cardiovascular disease
    Malissa J Wood
    Division of Cardiology, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston, Mass 02114, USA
    Am Heart J 145:806-12. 2003
    ..Complementary and alternative medical (CAM) therapies are becoming increasingly popular, yet little information is available about the prevalence and patterns of CAM therapy use by patients with cardiovascular disease (CVD)...
  38. doi Integrative medicine: enhancing quality in primary health care
    Sandra Grace
    The Education for Practice Institute, Charles Sturt University, Sydney, New South Wales, Australia
    J Altern Complement Med 16:945-50. 2010
    ..The aim of the research was to understand the contribution IM can make to the quality of primary care practices from the perspectives of consumers and providers of IM...
  39. doi CAM practitioners in integrative practice in New South Wales, Australia: a descriptive study
    Sandra Grace
    Department of Health and Chiropractic, Macquarie University, 2109 NSW, Australia
    Complement Ther Med 16:42-6. 2008
    ..The aim of this study was to examine the role of complementary and alternative medical (CAM) practitioners in integrative practices where general practitioners (GPs) and CAM practitioners were co-located...
  40. doi Predictors of complementary and alternative medicine use in chronic pain patients
    S Khady Ndao-Brumblay
    Department of Health Management and Policy, University of Michigan School of Public Health, Ann Arbor, Michigan, USA
    Pain Med 11:16-24. 2010
    ..Three practitioner-based alternative therapies were considered: acupuncture, biofeedback/relaxation training, and manipulation services...
  41. ncbi Correlates of use of different types of complementary and alternative medicine by breast cancer survivors in the nurses' health study
    Catherine Buettner
    Division for Research and Education in Complementary and Integrative Medical Therapies, Harvard Medical School, Boston, MA 02215 3325, USA
    Breast Cancer Res Treat 100:219-27. 2006
    ..Among breast cancer survivors, we identified the prevalence and correlates of use of different types of complementary and alternative medicine (CAM)...
  42. pmc Complementary and alternative therapies among very long-term breast cancer survivors
    C L Carpenter
    Center for Human Nutrition, David Geffen School of Medicine at UCLA, University of California at Los Angeles, Los Angeles, CA 90095, USA
    Breast Cancer Res Treat 116:387-96. 2009
    ..01). CAM users and non-users did not differ on the SF-36 physical sub-scale. Very long-term breast cancer survivors who use CAM may have poorer emotional functioning and more medical problems than non-users...
  43. pmc Management of primary chronic headache in the general population: the Akershus study of chronic headache
    Espen Saxhaug Kristoffersen
    Head and Neck Research Group, Research Centre, Akershus University Hospital, 1478 Lørenskog, Oslo, Norway
    J Headache Pain 13:113-20. 2012
    ..Thus, avoidance of acute headache medication overuse and increased use of prophylactic medication may improve the management of primary chronic headaches in the future...
  44. ncbi Frequent use of complementary medicine by prostate cancer patients
    Anton Ponholzer
    Department of Urology and Andrology, Donauspital SMZO, Langobardenstrasse 122, A 1220, Vienna, Austria
    Eur Urol 43:604-8. 2003
    ..To assess the use of complementary and alternative medicine (CAM) by prostate cancer patients and to characterize CAM-users in this population...
  45. ncbi Complementary and alternative medicine use by Canadian patients with inflammatory bowel disease: results from a national survey
    Robert J Hilsden
    Department of Medicine, University of Calgary, Calgary, Alberta, Canada
    Am J Gastroenterol 98:1563-8. 2003
    ..The aim of this study was to determine the prevalence of use and perceived outcomes of CAM in a large, diverse IBD population...
  46. ncbi The integration of complementary therapies in Australian general practice: results of a national survey
    Marc M Cohen
    School of Health Sciences, RMIT University, Bundoora, Victoria, Australia
    J Altern Complement Med 11:995-1004. 2005
    Australian general practitioners' (GPs) attitudes toward and use of a range of complementary therapies (CTs) were determined through a self-administered postal survey sent to a random sample of 2000 Australian GPs...
  47. ncbi Use of complementary and alternative medicine among American women
    Dawn M Upchurch
    UCLA School of Public Health, University of California Los Angeles, 650 Charles Young Drive South, Los Angeles, CA 90095 1722, USA
    Womens Health Issues 15:5-13. 2005
    ..The purpose of this study is to provide prevalence estimates of recent CAM use among American women and to examine sociodemographic and other characteristics associated with use...
  48. pmc What patients expect from complementary therapy: a qualitative study
    Janet Richardson
    School of Integrated Health, University of Westminster, 115 New Cavendish St, London W1W 6UW, England, UK
    Am J Public Health 94:1049-53. 2004
    ..Studies have suggested motivations for patients' choosing a wide range of complementary therapies. Data on the expectations of patients who use complementary therapy are limited...
  49. ncbi Alternative medicine use worldwide: the International Union Against Cancer survey
    B R Cassileth
    Integrative Medicine Service, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Cancer 91:1390-3. 2001
    ..In the current study, the authors attempted to surmount the deficiencies of previous surveys and elicit information regarding the use of alternative treatments of cancer worldwide...
  50. ncbi Determinants of the use of complementary therapies by patients with cancer
    O Paltiel
    Department of Social Medicine and School of Public Health, Hadassah Medical Center, Hebrew University, Jerusalem, Israel
    J Clin Oncol 19:2439-48. 2001
    We performed a survey of Israeli oncology patients to examine the extent of their use of complementary therapies (CT) and to compare sociodemographic, psychologic, and medical characteristics, attitudes, and quality of life of users and ..
  51. ncbi Uncharted ground: patterns of professional interaction among complementary/alternative and biomedical practitioners in integrative health care settings
    Daniel Hollenberg
    Department of Public Health Sciences, University of Toronto, 12 Queen s Park Crescent West, Room 103K, McMurrich Building, Toronto, Ont, Canada M5S 1A8
    Soc Sci Med 62:731-44. 2006
    ....
  52. doi Complementary and alternative medicine use by primary care patients with chronic pain
    Eric I Rosenberg
    Division of Internal Medicine, Department of Medicine, University of Florida, Gainesville, Florida 32610 0277, USA
    Pain Med 9:1065-72. 2008
    ..To describe the characteristics and attitudes toward complementary and alternative medicine (CAM) use among primary care patients with chronic pain disorders and to determine if CAM use is associated with better pain control...
  53. ncbi The use of complementary medicine and therapies by patients attending a reproductive medicine unit in South Australia: a prospective survey
    Marcin Stankiewicz
    Department of Obstetrics Gynaecology and Reproductive Medicine, Flinders Medical Centre, South Australia, Australia
    Aust N Z J Obstet Gynaecol 47:145-9. 2007
    ..There is limited research describing the use of complementary medicines (CM) and therapies among patients with infertility...
  54. ncbi High use of complementary therapies in a New South Wales rural community
    J M Wilkinson
    School of Biomedical Sciences, Charles Sturt University, Wagga Wagga, New South Wales, Australia
    Aust J Rural Health 9:166-71. 2001
    In this study a postal questionnaire was used to investigate the use of complementary therapies (CT) in a rural region of New South Wales (NSW). A total of 70.3% of respondents reported using one or more therapies with 62...
  55. ncbi Use of alternative medicine by patients with cancer in a rural area of Switzerland
    Fleur van der Weg
    Department of Medicine, SRO Hospital Langenthal, Switzerland
    Swiss Med Wkly 133:233-40. 2003
    ..Many cancer patients use alternative therapies in addition to conventional treatment. In a survey among such patients, we assessed the prevalence of and the motivation for alternative therapy use in a rural area of Switzerland...
  56. ncbi A systematic review of beliefs involved in the use of complementary and alternative medicine
    Felicity L Bishop
    Complementary Medicine Research Unit, University of Southampton
    J Health Psychol 12:851-67. 2007
    ..Further research should examine the robustness of these relationships in different illness groups and the prospective relationships among beliefs and CAM use over time...
  57. ncbi Complementary and alternative medicine use among adults with diabetes in the United States
    Ronny A Bell
    Division of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, NC, USA
    Altern Ther Health Med 12:16-22. 2006
    ....
  58. ncbi Herb and supplement use in the US adult population
    Jae Kennedy
    Dept Of Health Policy And Administrastion, College of Pharmacy, Washington State Uniuversity, Spokane, WA 99210, USA
    Clin Ther 27:1847-58. 2005
    ..Research on the scope of use and factors associated with herbal medicine use is limited...
  59. ncbi The placebo effect in alternative medicine: can the performance of a healing ritual have clinical significance?
    Ted J Kaptchuk
    Harvard Medical School, Boston, Massachusetts, USA
    Ann Intern Med 136:817-25. 2002
    ..nonspecific psychosocial effects have more positive health outcomes than a proven, specific conventional treatment? What makes therapy legitimate, positive clinical outcomes or culturally acceptable methods of attainment? Who decides?..
  60. ncbi Complementary and alternative medicine use and substitution for conventional therapy by HIV-infected patients
    An Fu Hsiao
    Division of General Internal Medicine and Health Services Research, Department of Medicine, University of California Los Angeles, 911 Broxton Plaza, Los Angeles, CA 90095 1736, USA
    J Acquir Immune Defic Syndr 33:157-65. 2003
    ..HIV-infected patients commonly use complementary and alternative medicine (CAM), but it is not known how often CAM is used as a complement or as a substitute for conventional HIV therapy...
  61. ncbi Integrative medicine: bringing medicine back to its roots
    Ralph Snyderman
    Duke University Medical Center, Box 3701, Durham, NC 27710, USA
    Arch Intern Med 162:395-7. 2002
  62. ncbi Attitudes of Australian pharmacists toward complementary and alternative medicines
    Sarushka Naidu
    School of Biomedical Sciences, Charles Sturt University, Wagga Wagga NSW, Australia
    Ann Pharmacother 39:1456-61. 2005
    ..The increase in the use of complementary and alternative medicine (CAM) by the general public has led to increasing interest in how health professionals view these therapies...
  63. ncbi Women's health during mid-life survey: the use of complementary and alternative medicine by symptomatic women transitioning through menopause in Sydney
    Corinne Patching van der Sluijs
    CompleMED Research Centre, University of Western Sydney, New South Wales, Australia
    Menopause 14:397-403. 2007
    ..To survey the extent of complementary and alternative medicine (CAM) use among women for the alleviation of menopausal symptoms...
  64. pmc 'They don't ask me so I don't tell them': patient-clinician communication about traditional, complementary, and alternative medicine
    Brian M Shelley
    First Choice Community Healthcare, Albuquerque, New Mexico 87105, USA
    Ann Fam Med 7:139-47. 2009
    ..Such communication can be important in anticipating possible drug-herb interactions and in assuring agreement about therapeutic plans...
  65. ncbi Complementary and alternative therapies for low back pain
    Maurits W van Tulder
    Institute for Research in Extramural Medicine, VU University Medical Center, Van der Boechorststraat 7, 1081 BT Amsterdam, The Netherlands
    Best Pract Res Clin Rheumatol 19:639-54. 2005
    ..In summary, the results on CAM therapies for (acute episodes of) chronic LBP are promising but more evidence on the relative cost-effectiveness compared to conventional treatments is needed...
  66. pmc A cross-sectional survey of complementary and alternative medicine use by children and adolescents attending the University Hospital of Wales
    Nigel W Crawford
    Department of General Paediatrics, University Hospital of Wales, Heath Park, Cardiff CF14 4XW, UK
    BMC Complement Altern Med 6:16. 2006
    ..The primary aim of this study was to examine the use of CAM by children and adolescents with a wide spectrum of acute and chronic medical problems in a tertiary children's hospital in Wales...
  67. doi Dietary supplement use in individuals living with cancer and other chronic conditions: a population-based study
    Melissa Farmer Miller
    Cancer Prevention Fellowship Program, National Cancer Institute, 6116 Executive Blvd, Ste 404, MSC 8336, Bethesda, MD 20892, USA
    J Am Diet Assoc 108:483-94. 2008
    ..Our objective was to compare supplement use among those with and without cancer and among those with and without other chronic conditions, and to identify correlates of supplement use by cancer status...
  68. doi Adverse events associated with the use of complementary and alternative medicine in children
    Alissa Lim
    Department of General Medicine, Royal Children s Hospital, Parkville, Melbourne, Australia
    Arch Dis Child 96:297-300. 2011
    ..To determine the types of adverse events associated with the use of complementary and alternative medicine (CAM) that come to the attention of Australian paediatricians...
  69. ncbi Why patients use alternative medicine: results of a national study
    J A Astin
    Stanford Center for Research in Disease Prevention, Stanford University School of Medicine, Palo Alto, Calif 94304 1583, USA
    JAMA 279:1548-53. 1998
    ..Research both in the United States and abroad suggests that significant numbers of people are involved with various forms of alternative medicine. However, the reasons for such use are, at present, poorly understood...
  70. ncbi Use of nonmedical treatments by infertility patients
    Jonathan Schaffir
    Department of Obstetrics and Gynecology, The Ohio State University College of Medicine, Columbus, Ohio, USA
    J Reprod Med 54:415-20. 2009
    ..To discover the extent to which infertility patients use alternatives to traditional medical treatment and to identify factors that may promote patients to use them...
  71. ncbi What is important in treating osteoarthritis? Whom should we treat and how should we treat them?
    Paul Dieppe
    Medical Research Council, Health Services Research Collaboration, Department of Social Medicine, University of Bristol, Canyge Hall, Whiteladies Road, Bristol BS8 2PR, UK
    Rheum Dis Clin North Am 29:687-716. 2003
    ..The authors also believe that the academic community striving to provide help for people who have OA should bear in mind the concept that there is "too much medicine" [37]...
  72. ncbi Developing a measure of treatment beliefs: the complementary and alternative medicine beliefs inventory
    F L Bishop
    Department of Psychology, University of Southampton, Highfield, Southampton SO17 1BJ, UK
    Complement Ther Med 13:144-9. 2005
    ..The study aimed to develop a comprehensive generic measure of treatment beliefs, the Complementary and Alternative Medicine Beliefs Inventory (CAMBI), and to identify distinct dimensions of CAM-related beliefs...
  73. pmc Australian women's use of complementary and alternative medicines to enhance fertility: exploring the experiences of women and practitioners
    Jo Anne Rayner
    Mother and Child Health Research, La Trobe University, 324 328 Little Lonsdale St, Melbourne, Victoria 3000, Australia
    BMC Complement Altern Med 9:52. 2009
    ..It is likely that CAM use for fertility enhancement will also increase, however this is not known. This paper reports on an exploratory study of women's use of CAM for fertility enhancement...
  74. ncbi Reasons for and characteristics associated with complementary and alternative medicine use among adult cancer patients: a systematic review
    Marja J Verhoef
    Department of Community Health Sciences, University of Calgary, Calgary, Alberta, Canada
    Integr Cancer Ther 4:274-86. 2005
    ..To conduct a systematic review of reasons for and sociodemographic and disease characteristics associated with complementary and alternative medicine (CAM) use in cancer patients...
  75. ncbi The influence of significant others in complementary and alternative medicine decisions by cancer patients
    Joakim Ohlen
    Department of Nursing, Karolinska Institute, Sweden
    Soc Sci Med 63:1625-36. 2006
    ..The findings of this inquiry extend previous research by highlighting the importance of significant others in cancer patients' CAM decisions and challenge past conceptualizations of autonomy in treatment decision making...
  76. ncbi Naprapathic manual therapy or evidence-based care for back and neck pain: a randomized, controlled trial
    Eva Skillgate
    Institute of Environmental Medicine, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Clin J Pain 23:431-9. 2007
    ....
  77. doi Intuition, subjectivity, and Le bricoleur: cancer patients' accounts of negotiating a plurality of therapeutic options
    Alex Broom
    University of Sydney, Sydney, New South Wales, Australia
    Qual Health Res 19:1050-9. 2009
    ....
  78. ncbi Cancer as part of the journey: the role of spirituality in the decision to decline conventional prostate cancer treatment and to use complementary and alternative medicine
    Margaret White
    Integr Cancer Ther 5:117-22. 2006
    ..Objective: To explore the role of spirituality in cancer management by men with prostate cancer who have declined conventional treatment and are using CAM...
  79. pmc Use of complementary and alternative medicines by a sample of Turkish women for infertility enhancement: a descriptive study
    Tamer Edirne
    Department of Family Medicine, University of Yuzuncu Yil, Van, Turkey
    BMC Complement Altern Med 10:11. 2010
    ..We investigated the prevalence and types of complementary and alternative medicine (CAM) used by infertile Turkish women for fertility enhancement...
  80. ncbi Amount of systemic steroid medication is a strong predictor for the use of complementary and alternative medicine in patients with inflammatory bowel disease: results from a German national survey
    Jost Langhorst
    Department of Internal Medicine, Kliniken Essen Mitte, Germany
    Inflamm Bowel Dis 11:287-95. 2005
    ..To further elucidate this phenomenon, we sent questionnaires to a large sample of IBD patients in Germany to determine the patterns and predictors of their CAM use...
  81. pmc Use of complementary and alternative medicine at Norwegian and Danish hospitals
    Laila J Salomonsen
    National Research Center in Complementary and Alternative Medicine, NAFKAM Faculty of health science, University of Tromsø, Norway
    BMC Complement Altern Med 11:4. 2011
    ..However, little is known about whether CAM is offered in hospitals. The aim of this study was to describe to what extent CAM is offered in Norwegian and Danish hospitals and investigate possible changes in Norway since 2001...
  82. pmc The influence of a series of five dry cupping treatments on pain and mechanical thresholds in patients with chronic non-specific neck pain--a randomised controlled pilot study
    Romy Lauche
    Alfried Krupp von Bohlen und Halbach Foundation, University of Duisburg Essen, Knappschafts Krankenhaus, Am Deimelsberg 34a, 45276 Essen, Germany
    BMC Complement Altern Med 11:63. 2011
    ..Sensory mechanical thresholds and the participants' self-reported outcome measures of pain and quality of life were evaluated...
  83. pmc A comparison of complementary and alternative medicine users and use across geographical areas: a national survey of 1,427 women
    Jon Adams
    Faculty of Nursing Midwifery and Health, University of Technology Sydney, Sydney, New South Wales, Australia
    BMC Complement Altern Med 11:85. 2011
    ....
  84. pmc Use of complementary and alternative medicine and self-rated health status: results from a national survey
    Long T Nguyen
    Division for Research and Education in Complementary and Integrative Medical Therapies, Harvard Medical School Osher Research Center, 401 Park Drive, Suite 22 A West, Boston, MA 02215, USA
    J Gen Intern Med 26:399-404. 2011
    ..Despite the absence of conclusive evidence of effectiveness, complementary and alternative medicine (CAM) is used by 4 of 10 adults in the US; little is known about the association between CAM use and health status...
  85. doi Use of and attitudes toward complementary and alternative medicine among nurse-midwives in Israel
    Noah Samuels
    The Center for Integrative Complementary Medicine, Shaare Zedek Medical Center, Jerusalem, Israel
    Am J Obstet Gynecol 203:341.e1-7. 2010
    ..The objective of the study was to evaluate the use and attitudes of nurse-midwives in Israel toward complementary and alternative medicine (CAM)...
  86. doi Complementary and alternative medicine (CAM) use among children with current asthma
    Joannie Shen
    Air Pollution and Respiratory Health Branch, Division of Environmental Hazards and Health Effects, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA
    Prev Med 54:27-31. 2012
    ..To estimate the prevalence of complementary and alternative medicine (CAM) use among children with current asthma...
  87. doi Prevalence and determinants of complementary and alternative medicine use during pregnancy: results from a nationally representative sample of Australian pregnant women
    Jane Frawley
    Faculty of Health, University of Technology Sydney, Sydney, New South Wales, Australia
    Aust N Z J Obstet Gynaecol 53:347-52. 2013
    ..Pregnant women have been identified as high users of complementary and alternative medicine (CAM). However, no research to date has provided a detailed analysis of the prevalence and determinants of CAM consumption amongst pregnant women...
  88. pmc Complementary and alternative medicine modality use and beliefs among African American prostate cancer survivors
    Randy A Jones
    School of Nursing, University of Virginia, Charlottesville, VA, USA
    Oncol Nurs Forum 34:359-64. 2007
    ..To examine the cultural beliefs and attitudes of African American prostate cancer survivors regarding the use of complementary and alternative medicine (CAM) modalities...
  89. pmc Alternative medicine research in clinical practice: a US national survey
    Jon C Tilburt
    Division of General Internal Medicine, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
    Arch Intern Med 169:670-7. 2009
    ..We sought to describe the awareness of CAM clinical trials, the ability to interpret research results, the acceptance of research evidence, and the predictors of trial awareness among US clinicians...
  90. ncbi Complementary and alternative medicine among advanced cancer patients enrolled on phase I trials: a study of prognosis, quality of life, and preferences for decision making
    Fay J Hlubocky
    Department of Medicine, Section of Hematology Oncology, MacLean Center for Clinical Medical Ethics, The Cancer Research Center, The University of Chicago, Chicago, IL 60637, USA
    J Clin Oncol 25:548-54. 2007
    ..We sought to describe complementary and alternative medicine (CAM) usage among phase I trial participants and to describe these patients' treatment decision-making preferences, awareness of prognosis, survival, and quality of life...
  91. doi Interprofessional collaboration within Canadian integrative healthcare clinics: Key components
    Isabelle Gaboury
    Department of Community Health Science, University of Calgary, Alberta, Canada
    Soc Sci Med 69:707-15. 2009
    ..These factors are critical to better understand the functioning of IHC clinics, and provide guidance for creation or maintenance of successful clinics...
  92. doi Complementary and alternative medicine use among Turkish diabetes patients
    Süleyman Ceylan
    Department of Public Health, Gulhane Military Medical Academy, GATA Halk Sağliği, AD 06018 Etlik, Ankara, Turkey
    Complement Ther Med 17:78-83. 2009
    ....
  93. ncbi Consultations with a naturopath or herbalist: the prevalence of use and profile of users amongst mid-aged women in Australia
    J Adams
    Epidemiology and Social Medicine Division, School of Population Health, University of Queensland, Rm 333, Public Health Building, Herston Rd, Herston, QLD 4006, Australia
    Public Health 121:954-7. 2007
  94. ncbi Patients' perceptions of primary care physicians' participatory decision-making style and communication about complementary and alternative medicine for arthritis
    Betsy Sleath
    University of North Carolina School of Pharmacy, Chapel Hill, NC 27599 7590, USA
    J Altern Complement Med 11:449-53. 2005
    ....
  95. pmc Any difference? Use of a CAM provider among cancer patients, coronary heart disease (CHD) patients and individuals with no cancer/CHD
    Agnete E Kristoffersen
    Department of Community Medicine, National Research Center in Complementary and Alternative Medicine, Tromsø, Norway
    BMC Complement Altern Med 12:1. 2012
    ....
  96. ncbi Variations in provider conceptions of integrative medicine
    An Fu Hsiao
    UCI Center for Health Policy Research Irvine, CA, USA
    Soc Sci Med 62:2973-87. 2006
    ..They advocated an open-minded perspective about other healing traditions, promoting co-management with and making referrals to practitioners of other paradigms, and treating patients with both CAM and conventional healing modalities...
  97. doi Emerging complementary and alternative medicine policy initiatives and the need for dialogue
    Kjersti E Knox
    Unit for Studies of Integrative Health Care, Division of Nursing, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, Huddinge, Sweden
    J Altern Complement Med 15:959-62. 2009
    ..In response to these challenges, many countries have established or are in the process of establishing a national CAM policy...
  98. pmc A survey describing the use of complementary therapies and medicines by women attending a family planning clinic
    Caroline A Smith
    Centre for Complementary Medicine Research, University of Western Sydney, Penrith, Australia
    BMC Complement Altern Med 13:224. 2013
    ..The aim of this study was to examine (i) the extent of and type of CM, (ii) women's views about safety and efficacy, and (iii) the factors influencing women's decision-making...
  99. doi Patient disclosure of the use of complementary and alternative medicine to their obstetrician/gynaecologist
    J T Harrigan
    Department of Obstetrics and Gynecology, Robert Wood Johnson Medical School, University of Medicine and Dentistry of New Jersey, USA
    J Obstet Gynaecol 31:59-61. 2011
    ..Of the 2,673 women seeing an obstetrician/gynaecologist 956 (35.8%) used at least one form of CAM. However, only 51.8% of the women using CAM disclosed that use to their physician...
  100. ncbi Normal medical practice of referring patients for complementary therapies among Australian general practitioners
    G Easthope
    School of Sociology and Social Work, University of Tasmania, Hobart, Tasmania
    Complement Ther Med 8:226-33. 2000
    Assessing the extent to which general practitioners (GPs) accept complementary therapies as normal medical practice.
  101. doi Integration of complementary and alternative medicine into medical schools in Austria, Germany and Switzerland--results of a cross-sectional study
    Benno Brinkhaus
    Institute of Social Medicine, Epidemiology and Health Economics, Charite University Medical Center, Berlin, Germany
    Wien Med Wochenschr 161:32-43. 2011
    ..The aims of this study were to evaluate the current opinions on CAM from decision makers at medical schools in three German-speaking countries and the present extent to which it has been integrated...

Research Grants76

  1. EFFECT OF CRANBERRY CONSTITUENTS ON UTI PATHOGENESIS
    Scott Hultgren; Fiscal Year: 2007
    ..This work will lead to a molecular under standing of the bioactivities of defined cranberry constituents on UPEC pathogenesis and may lead to better treatments for UTIs. ..
  2. Regulation of microRNA-375 by cyclic-AMP in pancreatic beta-cells
    DAVID MATTHEW KELLER; Fiscal Year: 2010
    ..This proposal will characterize a new target of cAMP signaling, microRNA-375, which has the potential to be used as a complementary therapy to enhance the efficacy of existing therapeutics that target the cAMP signaling pathway. ..
  3. Contribution of c-Jun N-terminal kinase activity to vestibular schwannoma growth
    Marlan R Hansen; Fiscal Year: 2013
    ..The results of these studies will provide insights into the fundamental mechanisms contributing to VS cell growth and radiosensitivity and will likely contribute to the development of novel therapies for VSs. ..
  4. Genetic Susceptibility and Biomarkers of Platinum-related Toxicities
    Lois B Travis; Fiscal Year: 2013
    ..Our results will eventually permit identification of patients at high risk for long-term toxicity, and the development of preventive and interventional strategies. 1 ..
  5. Enhancing radiation and cisplatin HNSCC cell killing by inhibiting mitochondrial
    Lynn Harrison; Fiscal Year: 2013
    ..Therefore there is a need to develop new complementary therapies to improve cell killing by radiation and cisplatin...
  6. Use of umbilical cord as a unique stem cell source for tissue regeneration
    Xiao Dong Chen; Fiscal Year: 2013
    ....
  7. Hepatic Lipase and HCV Infection
    Tianyi Wang; Fiscal Year: 2010
    ..Such knowledge is critical for the future development of novel antiviral therapies. ..
  8. High-throughput Screenings to Identify Host Receptors for Staphylococcal Adhesins
    Renata Pasqualini; Fiscal Year: 2012
    ..Our research aims to better understand staphylococcal infection and to set the grounds for targeted therapies against this disease. ..
  9. Exploring the Impact of Negative Energy Balance in Men with Prostate Cancer
    Wendy Demark-Wahnefried; Fiscal Year: 2013
    ..e., side-effects and medical outcomes , quality of life (QoL), and functional status. Such data are foundational and may ultimately lead to novel complementary therapies in this patient population.
  10. Proteolytic Pathways in Thrombus Resolution
    Toni M Antalis; Fiscal Year: 2013
    ..The objectives of this basic research proposal are therefore of direct relevance to a serious condition that impacts the health of the warfighter, the military family, and the American public. ..
  11. Volumetric Perfusion MRI of Liver Tumors to Detect Early Response to Chemotherapy
    Scott B Reeder; Fiscal Year: 2010
    ..Using the new perfusion MRI methods, the effectiveness of the drug will be ascertained in 2 days, and the prolonged use of ineffective, toxic and expensive drugs can be avoided and alternative therapies pursued. ..
  12. Omega-3 Fatty Acids &Psychoeducational Psychotherapy for Childhood Depression
    Mary A Fristad; Fiscal Year: 2013
    ....
  13. Biomarkers to Guide Treatment and Improve Survival in Oral/Oropharyngeal Cancer
    Thomas E Carey; Fiscal Year: 2012
    ..The results of this investigation will lead to new treatment strategies that are individualized for each patient. ..
  14. Connective Tissue Mechanotransduction
    Helene M Langevin; Fiscal Year: 2012
    ....
  15. CD8+ T Cell Immunity to Cytomegalovirus
    Stanley R Riddell; Fiscal Year: 2013
    ....
  16. Mission Reconnect: Promoting Resilience and Reintegration of Post-Deployment Vete
    Janet Kahn; Fiscal Year: 2013
    ..Innovation. The project leverages the dyadic relationship as a context for reciprocal and mutual use of complementary therapies for health promotion in both the veteran and partner...
  17. Protein-DNA Drug Carriers for Tumor Targeting
    Lali K Medina-Kauwe; Fiscal Year: 2012
    ..As HER2+ breast cancer does not respond well to conventional therapies, this alternative therapy could provide a significant contribution to breast cancer treatment, and could be modified to target therapy to other types of cancer. ..
  18. CRCNS: Propagation of beta oscillations in cortico-basal ganglia-thalamic loop
    Michelle M McCarthy; Fiscal Year: 2013
    ....
  19. The role of TC-PTP in skin carcinogenesis
    Dae Joon Kim; Fiscal Year: 2013
    ....
  20. VSL for Asthma
    Alessio Fasano; Fiscal Year: 2010
    ..Based on studies in other cohorts consuming VSL#3, we expect that VSL#3 will divert the immune system to a regulatory or tolerant mode with increased IL-10 production and downregulation of TH-2 cytokines IL- 4, IL-5, and IL-13. ..
  21. Development of Novel AIDS Gene Therapy Strategies in the Macaque SHIV Model
    Hans Peter Kiem; Fiscal Year: 2012
    ..If successful the proposed studies will lead to novel approaches to protect individuals from AIDS using stem cell gene therapy. ..
  22. Imaging cellular energy metabolism in brain slices using fluorescent biosensors
    REBECCA ANNE MONGEON; Fiscal Year: 2013
    ....
  23. IMMUNOBIOLOGY OF AGING
    CHARLES GARRISON FATHMAN; Fiscal Year: 2010
    ..We will develop an open-access data repository that will enable free sharing of high throughput analyte data and appropriately de-identified phenotypic data on a web-based platform using high quality open source and statistical tools. ..
  24. The Role of Adenosine in Ketogenic Diet Therapy
    Susan A Masino; Fiscal Year: 2013
    ..Ultimately, understanding the relationship between adenosine and ketogenic diet therapy will facilitate development of an entirely new family of treatments for epilepsy that are easy to administer, effective and well-tolerated. ..
  25. PCI Alternative Using Sustained Exercise (PAUSE)
    JONATHAN NEIL MYERS; Fiscal Year: 2012
    ..Our overall objective is to demonstrate the utility of a non-invasive technology to document the efficacy of exercise as an alternative treatment strategy to PCI for coronary lesions. ..
  26. Device to Improve Treatment of Colorectal Cancer Using O2 Dependent Phosphorescen
    JASON MATTHEW ZAND; Fiscal Year: 2010
    ..The proposed device could significantly reduce patient suffering, while saving $2 billion dollars annually in excess healthcare costs. ..
  27. Mechanism of Action of L THP as an Alternative Therapy for Cocaine Addiction
    Lee Yuan Liu-Chen; Fiscal Year: 2013
    ..As one of the major side effects of L-THP is sedation, our proposed study may yield candidate drugs with less sedation, as we have demonstrated for L-ICP. ..
  28. MCJ function in mouse mammary tumor properties
    Mercedes Rincon; Fiscal Year: 2009
    ..Considering the strong need for chemotherapy response biomarkers in cancer, this project is highly relevant for human health. ..
  29. Targeted Therapies for Selected Phenotypes of Obstructive Sleep Apnea
    Jerome A Dempsey; Fiscal Year: 2010
    ....
  30. Excessive Lysosomal Exocytosis Triggers Pathogenic Mechanisms in Sialidosis Mice
    ALESSANDRA D'AZZO; Fiscal Year: 2013
    ..We also expect that the results from these studies will highlight new aspects of the pathogenesis of sialidosis that have the potential to advance the development of alternative therapies for this devastating childhood disease. ..
  31. Evaluation of a Novel Anti-Resorptive Therapy for Osteogenesis Imperfecta
    PATRICIA A COLLIN-OSDOBY; Fiscal Year: 2012
    ..Promising results from this pre-clinical study would justify initiating future clinical trials to evaluate Desosumab as a new possible therapeutic avenue and alternative to bisphosphonates for the treatment of human OI patients. ..
  32. Apoptosome Regulation in Leukemia by Protein Phosphatase 5 Hypoacetylation
    KRISTEN FOSS; Fiscal Year: 2013
    ..The proposed research seeks to identify therapeutic targets for the treatment of leukemia, which could be used to sensitize leukemia cells to chemotherapeutics, and ultimately lead to improved prognosis for leukemia patients. ..
  33. Prospective Study of Breast Cancer Survivorship
    Lawrence H Kushi; Fiscal Year: 2013
    ....
  34. Data Infrastructure for Post-Marketing Comparative Effectiveness Studies
    SEAN P HENNESSY; Fiscal Year: 2010
    ....
  35. Tai Chi for Knee Osteoarthritis
    Chenchen Wang; Fiscal Year: 2013
    ..Successful completion of the proposed study will demonstrate that Tai Chi is a simple, inexpensive, effective, durable treatment for a major disabling disease with great social and economic costs. ..
  36. Sleeping Beauty Mediated Therapy for Alpha V Beta 6-Expressing Pancreatic Cancer
    Kendra A Hyland; Fiscal Year: 2013
    ....
  37. Mechanisms of HIV Protease Inhibitor-Induced Lipid Dysregulation in Adipocytes
    BETH S ZHA; Fiscal Year: 2012
    ..Determining the underlying cellular/molecular mechanisms by which some of these drugs cause devastating metabolic diseases can allow us to develop new therapies that will counteract induction of these chronic illnesses. ..
  38. Probiotic Yogurt for the Treatment of Minimal Hepatic Encephalopathy
    Jasmohan S Bajaj; Fiscal Year: 2011
    ....
  39. Hot Flushes and SNPs of the Norepinephrine and Serotonin Transporter Genes
    ISTVAN JOZSEF MERCHENTHALER; Fiscal Year: 2012
    ..However, the response to these is heterogenous and might be due to individual gene variations. This proposal will identify these variations and their relationship to hot flushes. ..
  40. A novel anti-scar peptide for cutaneous wound repair
    Chia Soo; Fiscal Year: 2013
    ..To this day, there exist no FDA approved drugs for prevention of scar recurrence. This Phase I SBIR proposal focuses on optimizing the treatment regimen for F06-C40 and proving its safety and efficacy. ..
  41. Stroke with Transfusions Changing to Hydroxyurea
    Russell E Ware; Fiscal Year: 2010
    ..If hydroxyurea has efficacy for prevention of secondary stroke, it may also be beneficial for other children with SCA and cerebrovascular disease including those at risk for primary stroke. ..
  42. Driving tissue formation by inductive stem cell sheet technology
    Eben Alsberg; Fiscal Year: 2013
    ..The successful completion of the proposed work will provide the basis for a clinically relevant tissue engineering strategy for the repair of damaged articular cartilage. ..
  43. SsnB, a Chinese herb-derived selective TLR antagonist
    Daping Fan; Fiscal Year: 2013
    ..Elucidation of the molecular mechanism and confirmation of the in vivo anti-inflammatory activity will lead to the development of SsnB into a selective TLR2 and TLR4 antagonist and an anti-inflammatory agent. ..
  44. Sparing Conversion to Abnormal TCD Elevation
    Russell E Ware; Fiscal Year: 2012
    ..In the SCATE study, we propose to treat children with conditional TCD velocities with hydroxyurea versus observation alone, to determine the beneficial effects of hydroxyurea in this clinical setting. ..
  45. Hepatitis C Virus and Hepatocellular Carcinoma
    Srikanta Dash; Fiscal Year: 2013
    ..If these experiments are successful it will increase our understanding of the IFN-resistance mechanisms, overcome the resistance and clear the infection and prevent hepatocellular carcinoma. ..
  46. Pharmacology and Bioengineering of New Treatment of ITP
    Joseph P Balthasar; Fiscal Year: 2010
    ..Additionally, work conducted on this project may offer insight in the design of effective strategies for the treatment of all autoimmune conditions, which collectively affect 14-22 million Americans. ..
  47. Contribution of AMPK to motor neuron disease
    MARIA ANGELINA LIM; Fiscal Year: 2012
    ..This project ultimately hopes to further our understanding of the interplay between metabolic dysfunction and neurodegenerative disease, specifically in ALS, in order to develop alternative therapies to prevent and treat disease. ..
  48. Ginseng and its Constituents in Complementary Breast Cancer Therapy
    Laura Murphy; Fiscal Year: 2010
    ....
  49. Portable Mantram Meditation for Veterans with Military Related PTSD
    Jill E Bormann; Fiscal Year: 2013
    ..Currently, there are few complementary therapies that have been studied as first-line treatments for PTSD...
  50. Glycemic Load and Resistance Training on Endothelial Function and Inflammation
    Christian K Roberts; Fiscal Year: 2013
    ..Furthermore, due to individualized specificity of compliance issues for each patient, the arsenal of therapies for prescription needs to be large;the current proposal will potentially increase the range of therapies. ..
  51. Efficacy of Yoga as an Alternative Therapy for Smoking Cessation
    Beth C Bock; Fiscal Year: 2013
    ..This study builds on our programmatic line of research developing innovative, theory-driven smoking cessation therapies. ..
  52. Behavioral Economic Analysis of Medical Marijuana Use in HIV+ Patients
    Mark K Greenwald; Fiscal Year: 2013
    ..These findings will be disseminated to patients, providers and society to promote public health and informed policy debate. ..
  53. Erythropoietin-encoding mRNA for treatment of anemia
    Katalin Kariko; Fiscal Year: 2010
    ....
  54. A Monoclonal Cocktail for CDI
    ANDREW HIATT; Fiscal Year: 2012
    ..S. The recent characterization of an epidemic C. difficile strain with increased virulence and antibiotic resistance has made the development of alternative therapies even more pressing. ..
  55. Innate and adaptive immunity in celiac disease
    Bana Jabri; Fiscal Year: 2013
    ....
  56. TCD With Transfusions Changing to Hydroxyurea
    Russell E Ware; Fiscal Year: 2013
    ..End of Abstract) ..
  57. Mindfulness in Women with Polycystic Ovary Syndrome
    NAZIA T RAJA-KHAN; Fiscal Year: 2013
    ..program for Polycystic Ovary Syndrome (PCOS) aimed at integrating evidence-based non-conventional complementary therapies with conventional medical therapies for PCOS to optimize psychological and cardiometabolic health in PCOS...
  58. THE UCLA CENTER FOR IN VIVO IMAGING IN CANCER BIOLOGY
    Harvey R Herschman; Fiscal Year: 2013
    ....
  59. TCD with Transfusions Changing to Hydroxyurea - SDMC
    Barry R Davis; Fiscal Year: 2013
    ..abstract_text> ..
  60. Peer Mentorship: An Intervention to Promote Effective Pain Self-Management in Ad
    Lonnie K Zeltzer; Fiscal Year: 2010
    ..This research will test a peer- mentorship intervention that may promote adherence and skills-building through modeling and reinforcement, with positive effects on physical, social and academic functioning. ..
  61. Osteoporosis treatment response assessed by micromechanical modeling of MRI data.
    Felix W Wehrli; Fiscal Year: 2013
    ..The successful completion of the project will provide new insight into the potential for image-based computational biomechanics for monitoring prophylactic intervention. ..
  62. RNA As A Therapeutic Target
    Webster L Santos; Fiscal Year: 2013
    ..If successful, these molecules will be the next generation drugs with novel mode of action as anti-HIV therapy. ..
  63. Medical Food Cocktail for Alzheimer's Disease
    CURT H HENDRIX; Fiscal Year: 2010
    ..If effective for use as a complementary or alternative therapy, the medical food cocktail may drastically reduce the devastating economical and societal costs of Alzheimer's Disease. ..
  64. Etiology, Epidemiology, and Clinical Outcomes of Health Care Associated Pneumonia
    Karl Madaras Kelly; Fiscal Year: 2009
    ..This study will improve public health by helping health care providers choose the right antibiotics when treating Health Care Associated pneumonia and not using more antibiotics than necessary. ..
  65. VSL for Asthma
    Alessio Fasano; Fiscal Year: 2009
    ..Based on studies in other cohorts consuming VSL#3, we expect that VSL#3 will divert the immune system to a regulatory or tolerant mode with increased IL-10 production and downregulation of TH-2 cytokines IL- 4, IL-5, and IL-13. ..
  66. A Nonisotopic HTS Assay to Elucidate Choline Transporter (CHT) Modulators
    ALICIA RUGGIERO; Fiscal Year: 2009
    ....
  67. DEVELOPMENT OF AN ORAL DRUG FOR SMALLPOX TREATMENT
    George Painter; Fiscal Year: 2007
    ..Upon FDA approval, a Phase I trial will be initiated to evaluate the safety, tolerability and pharmacokinetics of a single, escalating dose in human volunteers. ..
  68. Immunomodulatory Mechanisms of Sublingual Immunotherapy
    Louis Rosenthal; Fiscal Year: 2006
    ..To investigate this controversial therapy, these studies will use a novel rat model to compare the efficacy of high vs. low doses of allergen drops and to elucidate mechanisms of sublingual immunotherapy. ..
  69. Novel Complementary Therapy for Preterm Infants
    John Bauer; Fiscal Year: 2009
    ..We will carry out preclinical studies to define mechanistic actions and identify optimal conditions for potential efficacy using relevant human fetal intestinal epithelial cells and animal models of newborn intestinal injury. ..
  70. Botanicals from Central America for Menopause
    Gail Mahady; Fiscal Year: 2005
    ..Successful validation and standardization of traditional plant-based medicines used to treat menopause has great significance not only for the women of Central America but the rest of the world as well. ..
  71. PPAR- GAMMA LIGANDS IN ULCERATIVE COLITIS
    James Lewis; Fiscal Year: 2001
    ..It is expected that in the final 6 months of this project, the investigators will organize a multicenter randomized controlled trial of troglitazone in the treatment of mild to moderate ulcerative colitis. ..
  72. Care Choices and Costs for Low Back Pain
    Sylvia Kuo; Fiscal Year: 2006
    ..Such strategies may help reduce the health care expenditures associated with LBP. The findings from this proposed research will lead to a larger study which would examine outcomes and costs. [unreadable] [unreadable] [unreadable]..
  73. First International Congress on Fascia Research: Basic Science and Implications f
    Thomas Findley; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  74. A Pharmacokinetic Study of glucosamine and chondroitin
    Christopher Jackson; Fiscal Year: 2005
    ..The use of alternative and complementary therapies in the treatment of osteoarthritis is common and particular interest has focused on glucosamine and ..
  75. Pneumocystis Biochemistry: Ubiquinones
    EDNA KANESHIRO; Fiscal Year: 2002
    ..carinii CoQ biosynthesis and growth in axenic cultures, and (4) develop atovaquone-resistant P. carinii populations to evaluate CoQ synthesis in sensitive and resistant organisms. ..
  76. A Genetic Test for Drug-Induced Dyskinesia Risk Determination
    Abraham Kovoor; Fiscal Year: 2007
    ..In addition, the ability to estimate dyskinesia risk will be very valuable in the development of new and improved antipsychotic and antiparkinsonian drugs. [unreadable] [unreadable] [unreadable] [unreadable]..