electroacupuncture

Summary

Summary: A form of acupuncture with electrical impulses passing through the needles to stimulate NERVE TISSUE. It can be used for ANALGESIA; ANESTHESIA; PHYSICAL REHABILITATION; and treatment for diseases.

Top Publications

  1. ncbi The effect of electroacupuncture on spontaneous recurrent seizure and expression of GAD(67) mRNA in dentate gyrus in a rat model of epilepsy
    Jianjun Guo
    Department of Analysis Measurement Science, College of Chemistry and Molecular Sciences, Wuhan University, Wuchang District, Wuhan, PR China
    Brain Res 1188:165-72. 2008
  2. ncbi Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies
    Ji Sheng Han
    Neuroscience Research Institute, Peking University, 38 Xue Yuan Road, Beijing 100083, China
    Trends Neurosci 26:17-22. 2003
  3. ncbi Effects of electroacupuncture versus manual acupuncture on the human brain as measured by fMRI
    Vitaly Napadow
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Hum Brain Mapp 24:193-205. 2005
  4. pmc Electroacupuncture increased cerebral blood flow and reduced ischemic brain injury: dependence on stimulation intensity and frequency
    Fei Zhou
    Shanghai Research Center for Acupuncture and Meridians, Shanghai, China
    J Appl Physiol (1985) 111:1877-87. 2011
  5. ncbi Acupuncture and endorphins
    Ji Sheng Han
    Neuroscience Research Institute, Peking University and Key Laboratory of Neuroscience Peking University, Ministry of Education, 38 Xue Yuan Road, Beijing 100083, PR China
    Neurosci Lett 361:258-61. 2004
  6. ncbi Effects of electroacupuncture at Zusanli and Baihui on brain-derived neurotrophic factor and cyclic AMP response element-binding protein in the hippocampal dentate gyrus
    In Koo Hwang
    Department of Anatomy and Cell Biology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, South Korea
    J Vet Med Sci 72:1431-6. 2010
  7. ncbi An fMRI study of neuronal specificity of an acupoint: electroacupuncture stimulation of Yanglingquan (GB34) and its sham point
    Byung Jo Na
    Department of Internal Medicine, Kang Nam Oriental Medicine Hospital, College of Oriental Medicine, Kyung Hee University, Gangnam Gu, Seoul, Republic of Korea
    Neurosci Lett 464:1-5. 2009
  8. pmc Neural mechanism of electroacupuncture's hypotensive effects
    Peng Li
    Department of Medicine, Susan Samueli Center for Integrative Medicine, University of California, Irvine, California 92697, USA
    Auton Neurosci 157:24-30. 2010
  9. ncbi Neuronal specificity of acupuncture response: a fMRI study with electroacupuncture
    Ming Ting Wu
    Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan, Republic of China
    Neuroimage 16:1028-37. 2002
  10. pmc Imaging the functional connectivity of the Periaqueductal Gray during genuine and sham electroacupuncture treatment
    Carolyn E Zyloney
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, USA
    Mol Pain 6:80. 2010

Detail Information

Publications324 found, 100 shown here

  1. ncbi The effect of electroacupuncture on spontaneous recurrent seizure and expression of GAD(67) mRNA in dentate gyrus in a rat model of epilepsy
    Jianjun Guo
    Department of Analysis Measurement Science, College of Chemistry and Molecular Sciences, Wuhan University, Wuchang District, Wuhan, PR China
    Brain Res 1188:165-72. 2008
    ..The purpose of this study was to investigate the effect of electroacupuncture (EA) on spontaneous recurrent seizure (SRS) and expression of GAD(67) mRNA in dentate gyrus (DG) in ..
  2. ncbi Acupuncture: neuropeptide release produced by electrical stimulation of different frequencies
    Ji Sheng Han
    Neuroscience Research Institute, Peking University, 38 Xue Yuan Road, Beijing 100083, China
    Trends Neurosci 26:17-22. 2003
  3. ncbi Effects of electroacupuncture versus manual acupuncture on the human brain as measured by fMRI
    Vitaly Napadow
    Athinoula A Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts 02129, USA
    Hum Brain Mapp 24:193-205. 2005
    The goal of this functional magnetic resonance imaging (fMRI) study was to compare the central effects of electroacupuncture at different frequencies with traditional Chinese manual acupuncture...
  4. pmc Electroacupuncture increased cerebral blood flow and reduced ischemic brain injury: dependence on stimulation intensity and frequency
    Fei Zhou
    Shanghai Research Center for Acupuncture and Meridians, Shanghai, China
    J Appl Physiol (1985) 111:1877-87. 2011
    ..Here we show an exciting finding that optimal electroacupuncture (EA) effectively protects the brain from ischemic injury...
  5. ncbi Acupuncture and endorphins
    Ji Sheng Han
    Neuroscience Research Institute, Peking University and Key Laboratory of Neuroscience Peking University, Ministry of Education, 38 Xue Yuan Road, Beijing 100083, PR China
    Neurosci Lett 361:258-61. 2004
    Acupuncture and electroacupuncture (EA) as complementary and alternative medicine have been accepted worldwide mainly for the treatment of acute and chronic pain...
  6. ncbi Effects of electroacupuncture at Zusanli and Baihui on brain-derived neurotrophic factor and cyclic AMP response element-binding protein in the hippocampal dentate gyrus
    In Koo Hwang
    Department of Anatomy and Cell Biology, College of Veterinary Medicine and Research Institute for Veterinary Science, Seoul National University, South Korea
    J Vet Med Sci 72:1431-6. 2010
    Previously, we observed that electroacupuncture (EA) at ST36 (Zusanli) and GV20 (Baihui) enhanced cell proliferation and neuroblast differentiation in the rat dentate gyrus...
  7. ncbi An fMRI study of neuronal specificity of an acupoint: electroacupuncture stimulation of Yanglingquan (GB34) and its sham point
    Byung Jo Na
    Department of Internal Medicine, Kang Nam Oriental Medicine Hospital, College of Oriental Medicine, Kyung Hee University, Gangnam Gu, Seoul, Republic of Korea
    Neurosci Lett 464:1-5. 2009
    ..The objective of this study was to investigate the neuronal specificity of an acupoint with electroacupuncture stimulation (EAS) using functional magnetic resonance imaging (fMRI)...
  8. pmc Neural mechanism of electroacupuncture's hypotensive effects
    Peng Li
    Department of Medicine, Susan Samueli Center for Integrative Medicine, University of California, Irvine, California 92697, USA
    Auton Neurosci 157:24-30. 2010
    ..Thus, a number of mechanisms underlying the long-lasting effect of EA on cardiovascular function have been identified but clearly further investigation is warranted...
  9. ncbi Neuronal specificity of acupuncture response: a fMRI study with electroacupuncture
    Ming Ting Wu
    Department of Radiology, Kaohsiung Veterans General Hospital, Kaohsiung 813, Taiwan, Republic of China
    Neuroimage 16:1028-37. 2002
    ..With the advantage of objective parameter setting, electroacupuncture (EA) was used in this study to devise three distinct controls for real EA, i.e...
  10. pmc Imaging the functional connectivity of the Periaqueductal Gray during genuine and sham electroacupuncture treatment
    Carolyn E Zyloney
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, USA
    Mol Pain 6:80. 2010
    b>Electroacupuncture (EA) is currently one of the most popular acupuncture modalities...
  11. ncbi The effects of electroacupuncture on TH1/TH2 cytokine mRNA expression and mitogen-activated protein kinase signaling pathways in the splenic T cells of traumatized rats
    Kun Wang
    Department of Anesthesiology, The Third Clinical Hospital, Harbin Medical University, Nangang District, Harbin 150081, China
    Anesth Analg 109:1666-73. 2009
    ..b>Electroacupuncture (EA) can alleviate pain and exert immunoregulatory effects...
  12. pmc Test-retest study of fMRI signal change evoked by electroacupuncture stimulation
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital MGH, MA, USA
    Neuroimage 34:1171-81. 2007
    ..in six identical scanning sessions consisting of four functional scans, one for each of the four conditions: electroacupuncture stimulation (2 Hz) at GB 37, UB 60, non-acupoint (NP), and a control task of the finger tapping...
  13. pmc Protective effect of electroacupuncture at the Neiguan point in a rabbit model of myocardial ischemia-reperfusion injury
    Hongxing Zhang
    Wuhan Chinese and Western Medicine Hospital, Wuhan, China
    Can J Cardiol 25:359-63. 2009
    To investigate possible cardioprotective mechanisms of electroacupuncture (EA) at the Neiguan point and at the Lieque point in the presence of myocardial ischemia-reperfusion injury (MIRI).
  14. pmc Long-loop pathways in cardiovascular electroacupuncture responses
    Peng Li
    Department of Medicine, University of California, Irvine, CA, USA
    J Appl Physiol (1985) 106:620-30. 2009
    We have shown that electroacupuncture (EA) at P 5-6 (overlying median nerves) activates arcuate (ARC) neurons, which excite the ventrolateral periaqueductal gray (vlPAG) and inhibit cardiovascular sympathoexcitatory neurons in the rostral ..
  15. ncbi Activation of epsilon protein kinase C-mediated anti-apoptosis is involved in rapid tolerance induced by electroacupuncture pretreatment through cannabinoid receptor type 1
    Qiang Wang
    Department of Anesthesiology, Fourth Military Medical University, Shaanxi Province, China
    Stroke 42:389-96. 2011
    Our previous study has demonstrated that the rapid tolerance to cerebral ischemia by electroacupuncture (EA) pretreatment was possibly mediated through an endocannabinoid system-related mechanism...
  16. ncbi Electroacupuncture improves impaired gastric motility and slow waves induced by rectal distension in dogs
    Jie Chen
    Division of Gastroenterology, University of Texas Medical Branch, Galveston, TX 77555 0632, USA
    Am J Physiol Gastrointest Liver Physiol 295:G614-20. 2008
    ..on gastric slow waves (GSW) and motor activity and furthermore to investigate the effects and mechanisms of electroacupuncture (EA) on GSW and motor activity...
  17. ncbi Electroacupuncture regulates TRPM7 expression through the trkA/PI3K pathway after cerebral ischemia-reperfusion in rats
    Li Zhao
    Department of Neurobiology, Key Laboratory of Neurological Disease of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, PR China
    Life Sci 81:1211-22. 2007
    ..In the present study, we found that electroacupuncture (EA) treatment could up-regulate trkA expression after focal cerebral ischemia in rats...
  18. ncbi Electroacupuncture regulates NMDA receptor NR1 subunit expression via PI3-K pathway in a rat model of cerebral ischemia-reperfusion
    Ning Sun
    Department of Neurobiology, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, P R China
    Brain Res 1064:98-107. 2005
    ..Clinically, electroacupuncture (EA) has been shown to produce beneficial effects on stroke patients...
  19. ncbi Pretreatment with electroacupuncture induces rapid tolerance to focal cerebral ischemia through regulation of endocannabinoid system
    Qiang Wang
    Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Xi an 710032, Shaanxi Province, China
    Stroke 40:2157-64. 2009
    Our previous study demonstrated that pretreatment with electroacupuncture (EA) induces rapid tolerance to focal cerebral ischemia...
  20. ncbi Effects of electroacupuncture on hippocampal and cortical apoptosis in a mouse model of cerebral ischemia-reperfusion injury
    Jian xin Zhao
    the Third Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100029, China
    J Tradit Chin Med 31:349-55. 2011
    To observe the effects of electroacupuncture on hippocampal and cortical apoptosis in a mouse model of cerebral ischemia-reperfusion injury.
  21. ncbi Electroacupuncture improves neurological deficits and enhances proliferation and differentiation of endogenous nerve stem cells in rats with focal cerebral ischemia
    Jing Tao
    Fujian College of Traditional Chinese Medicine, Fuzhou, China
    Neurol Res 32:198-204. 2010
    This study was carried out to observe the effect of electroacupuncture (EA) on neurological deficits, proliferation and differentiation of nerve stem cells (NSCs) in adult rats with middle cerebral artery occlusion (MCAO) and to study its ..
  22. ncbi Angiogenesis and improved cerebral blood flow in the ischemic boundary area were detected after electroacupuncture treatment to rats with ischemic stroke
    Yuanhao Du
    Acupuncture and Moxibustion Research Institute, First Hospital Affiliated to Tianjin University of Traditional Chinese Medicine, Tianjin, China
    Neurol Res 33:101-7. 2011
    ..Recent data have also shown that angiogenesis indeed brings benefit to cerebral circulation and behavior improvement. We examined the effect of electroacupuncture on vascular endothelial cell proliferation in the ischemic stroke model.
  23. ncbi [Electroacupuncture protects the brain against acute ischemic injury via up-regulation of delta-opioid receptor in rats]
    Xue song Tian
    National Key Laboratory of Medical Neurobiology, Department of Integrative Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Zhong Xi Yi Jie He Xue Bao 6:632-8. 2008
    To explore the effect of delta-opioid receptor (DOR) in electroacupuncture (EA) protecting the brain against acute ischemic injury.
  24. ncbi Analgesic effect of electroacupuncture on complete Freund's adjuvant-induced inflammatory pain in mice: a model of antipain treatment by acupuncture in mice
    W M Li
    Department of Integrative Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Jpn J Physiol 55:339-44. 2005
    b>Electroacupuncture (EA) was applied bilaterally to the acupoints of Zu-san-li (ST-36) and Kun-lun (BL-60) in the hindlimbs of mice...
  25. pmc Is functional state of spinal microglia involved in the anti-allodynic and anti-hyperalgesic effects of electroacupuncture in rat model of monoarthritis?
    Sun Shan
    Institute of Neurobiology, Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China
    Neurobiol Dis 26:558-68. 2007
    Spinal microglia play a key role for creating exaggerated pain following tissues inflammation or injury. Electroacupuncture (EA) can effectively control the exaggerated pain both in humans with inflammatory disease and animals with ..
  26. ncbi Excitatory amino acid receptor antagonists and electroacupuncture synergetically inhibit carrageenan-induced behavioral hyperalgesia and spinal fos expression in rats
    Yu Qiu Zhang
    Institute of Neurobiology, Fudan University, 220 Han Dan Road, Shanghai 200433, China
    Pain 99:525-35. 2002
    The interaction between electroacupuncture and an N-methyl-D-aspartic acid (NMDA) receptor antagonist, (DL-2-amino-5-phosphonopentanoic acid; AP5), or an (+/-)-alpha-Amino-3-hydroxy-5-methylisoxazole-4-propionic acid/kainite (AMPA/KA) ..
  27. ncbi Responses of neuronal nitric oxide synthase expression in the brainstem to electroacupuncture Zusanli (ST 36) in rats
    Sheng Xing Ma
    Department of Obstetrics and Gynecology, David Geffen School of Medicine at University of California Los Angeles, Harbor UCLA Medical Center, 1124 W Carson Street, RB 1, Torrance, CA 90502, USA
    Brain Res 1037:70-7. 2005
    ..that l-arginine-derived nitric oxide (NO) in the gracile nucleus modifies the hypotensive responses to electroacupuncture (EA) stimulation of Zusanli (ST 36)...
  28. ncbi Inhibitory effect of electroacupuncture (EA) on the pressor response induced by exercise stress
    Peng Li
    Dept of Medicine, University of California, Irvine Medical Science I, C235, Irvine, CA 92697 4075, USA
    Clin Auton Res 14:182-8. 2004
    ..We conclude that EA at specific acupoints improves exercise capacity and reduces the hemodynamic responses in approximately 70% of normal subjects...
  29. ncbi Imbalance between pro- and anti-inflammatory cytokines, and between Th1 and Th2 cytokines in depressed patients: the effect of electroacupuncture or fluoxetine treatment
    C Song
    Department of Biomedical Sciences, University of Prince Edward Island, Charlottetown, Canada
    Pharmacopsychiatry 42:182-8. 2009
    ..between pro- and anti-inflammatory cytokines and between Th1 and Th2 produced cytokines in depressed patients and 2) evaluate and compare the effect of treatments with electroacupuncture (EA) and fluoxetine on these cytokines.
  30. ncbi Effects of electroacupuncture on cold allodynia in a rat model of neuropathic pain: mediation by spinal adrenergic and serotonergic receptors
    Sun Kwang Kim
    Department of East West Medicine, Graduate School, Kyung Hee University, Dongdaemoon gu, Seoul, South Korea
    Exp Neurol 195:430-6. 2005
    The present study was performed to examine the effects of electroacupuncture (EA) on cold allodynia and its mechanisms related to the spinal adrenergic and serotonergic systems in a rat model of neuropathic pain...
  31. ncbi A parametric study of electroacupuncture on persistent hyperalgesia and Fos protein expression in rats
    Lixing Lao
    Center for Integrative Medicine, School of Medicine, University of Maryland, 3rd Floor, James Kernan Hospital Mansion, 2200 Kernan Drive, Baltimore, MD 21201, USA
    Brain Res 1020:18-29. 2004
    We previously reported the anti-hyperalgesia of electroacupuncture (EA) on persistent inflammatory pain in an unrestrained, unsedated, and conscious rat model...
  32. ncbi Long-term synaptic plasticity in the spinal dorsal horn and its modulation by electroacupuncture in rats with neuropathic pain
    Guo Gang Xing
    Department of Neurobiology, Key Laboratory for Neuroscience of the Ministry of Education and Public Health, Peking University, 38 Xue Yuan Road, Beijing 100083, People s Republic of China
    Exp Neurol 208:323-32. 2007
    Our previous study has reported that electroacupuncture (EA) at low frequency of 2 Hz had greater and more prolonged analgesic effects on mechanical allodynia and thermal hyperalgesia than that EA at high frequency of 100 Hz in rats with ..
  33. ncbi Electroacupuncture exerts anti-inflammatory effects in cerebral ischemia-reperfusion injured rats via suppression of the TLR4/NF-κB pathway
    Lan Lan
    College of Rehabilitation Medicine, Fujian University of Traditional Chinese Medicine, Fuzhou, Fujian 350122, PR China
    Int J Mol Med 31:75-80. 2013
    ..model, in the present study we evaluated the neuroprotective and anti-inflammatory activities of electroacupuncture at Quchi and Zusanli, and investigated the underlying molecular mechanisms...
  34. pmc Electroacupuncture acutely improves cerebral blood flow and attenuates moderate ischemic injury via an endothelial mechanism in mice
    Ji Hyun Kim
    Division of Meridian and Structural Medicine, School of Korean Medicine, Pusan National University, Yangsan, Gyeongnam, Republic of Korea
    PLoS ONE 8:e56736. 2013
    b>Electroacupuncture (EA) is a novel therapy based on traditional acupuncture combined with modern eletrotherapy that is currently being investigated as a treatment for acute ischemic stroke...
  35. ncbi Effect of electroacupuncture on motor recovery in a rat stroke model during the early recovery stage
    Won Seok Kim
    Department of Rehabilitation Medicine, Seoul National University College of Medicine, Yeon Gun Dong, Jongro Gu, Seoul, Republic of Korea
    Brain Res 1248:176-83. 2009
    ..The groups studied were a control, treadmill exercise, electroacupuncture and a combined treatment group with both treadmill exercise and electroacupuncture (ExEA)...
  36. ncbi The effect of brief electrical and manual acupuncture stimulation on mechanical experimental pain
    Juerg Schliessbach
    University Department of Anesthesiology and Pain Therapy, Inselspital Bern, Switzerland
    Pain Med 12:268-75. 2011
    ..This blinded, placebo-controlled cross-over study investigates effects of brief manual and electrical acupuncture stimulation on pressure pain detection thresholds (PPDT) compared with nonpenetrating sham acupuncture (NPSA)...
  37. ncbi Effect of electroacupuncture stimulation of hindlimb on seizure incidence and supragranular mossy fiber sprouting in a rat model of epilepsy
    Jianjun Guo
    College of Chemistry and Molecular Sciences, Wuhan University, Wuhan, People s Republic of China
    J Physiol Sci 58:309-15. 2008
    Recently, electroacupuncture (EA) has been gaining more and more attention as a treatment for epilepsy. However, concrete evidence is needed to better understand its antiepileptic effect and the mechanism underlying this effect...
  38. ncbi Involvement of spinal neurotrophin-3 in electroacupuncture analgesia and inhibition of spinal glial activation in rat model of monoarthritis
    Wen Li Mi
    Department of Integrative Medicine and Neurobiology, Institute of Acupuncture Research, State Key Laboratory of Medical Neurobiology, Institutes of Brain Science, Shanghai Medical College, Fudan University, Shanghai, China
    J Pain 12:974-84. 2011
    Although electroacupuncture (EA) has been proven to effectively relieve pain associated with arthritis, the underlying mechanism of EA analgesia requires further investigation...
  39. ncbi Low-frequency electro-acupuncture and physical exercise improve metabolic disturbances and modulate gene expression in adipose tissue in rats with dihydrotestosterone-induced polycystic ovary syndrome
    Louise Mannerås
    Institute of Neuroscience and Physiology, Department of Physiology, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden
    Endocrinology 149:3559-68. 2008
    ..In contrast to exercise, EA improves insulin sensitivity and modulates adipose tissue gene expression without influencing adipose tissue mass and cellularity...
  40. pmc The analgesic effect of electroacupuncture on acute thermal pain perception--a central neural correlate study with fMRI
    Shivshil Shukla
    Anesthesia Service, Veteran Administrations San Diego Healthcare System, 3350 La Jolla Village Drive, MC 125, San Diego, CA 92161, USA
    Mol Pain 7:45. 2011
    ..Subjects underwent five fMRI scanning paradigms: one with heat pain (HP), two with OI-EA and MI-EA, and two with OI-EA and HP, and MI-EA and HP...
  41. ncbi Antiepileptic effect of electroacupuncture vs. vagus nerve stimulation in the rat thalamus
    Jian Liang Zhang
    School of Chinese Medicine, Hong Kong Baptist University, Kowloon Tong, Hong Kong
    Neurosci Lett 441:183-7. 2008
    Our previous study has shown that both electroacupuncture (EA) and vagus nerve stimulation (VNS) can inhibit cortical epileptiform activities induced by pentylenetetrazole (PTZ)...
  42. ncbi Electroacupuncture reduces the expression of proinflammatory cytokines in inflamed skin tissues through activation of cannabinoid CB2 receptors
    T F Su
    Department of Neurobiology and Key Laboratory of Neurological Diseases of Hubei Province, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Eur J Pain 16:624-35. 2012
    ..cannabinoids and peripheral cannabinoid CB2 receptors (CB2Rs) are involved in the antinociceptive effect of electroacupuncture (EA) on inflammatory pain...
  43. ncbi Electroacupuncture frequency-related transcriptional response in rat arcuate nucleus revealed region-distinctive changes in response to low- and high-frequency electroacupuncture
    Ke Wang
    National Engineering Research Center for Biochip at Shanghai, Shanghai 201203, People s Republic of China
    J Neurosci Res 90:1464-73. 2012
    b>Electroacupuncture (EA) has been clinically applied for treating different medical conditions, such as pain, strain, and immune diseases...
  44. ncbi Comparing the effects of acupuncture and electroacupuncture at Zusanli and Baihui on cell proliferation and neuroblast differentiation in the rat hippocampus
    In Koo Hwang
    Department of Anatomy and Cell Biology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, Seoul 151 742, South Korea
    J Vet Med Sci 72:279-84. 2010
    We compared the effects of acupuncture and electroacupuncture on cell proliferation and neuroblast differentiation using specific markers, Ki67 and doublecortin (DCX), in the subgranular zone of the dentate gyrus (SZDG) in 13-week old ..
  45. ncbi Electro-acupuncture protects against hypoxic-ischemic brain-damaged immature rat via hydrogen sulfide as a possible mediator
    Ying Liu
    Department of Pediatrics, Chinese PLA General Hospital, 28, FuXing Road, Beijing, China
    Neurosci Lett 485:74-8. 2010
    ..Rats with HIBD receiving both EA and HA therapy showed greatly recovered motor function and brain morphology. H(2)S might be a mediator of EA treatment of HIBD in rats...
  46. ncbi Cannabinoid receptor type 2 activation yields delayed tolerance to focal cerebral ischemia
    Lei Ma
    Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi, 710032, China
    Curr Neurovasc Res 8:145-52. 2011
    We demonstrated in our previous research that pretreatment with electroacupuncture (EA) induces rapid (2h after EA) and delayed (24h after EA) tolerance to focal cerebral ischemia...
  47. pmc Processing cardiovascular information in the vlPAG during electroacupuncture in rats: roles of endocannabinoids and GABA
    Stephanie C Tjen-A-Looi
    School of Medicine, University of California, Irvine, CA 92697 4075, USA
    J Appl Physiol (1985) 106:1793-9. 2009
    ..ventrolateral periaqueductal gray (vlPAG), and the rostral ventrolateral medulla (rVLM), is essential in electroacupuncture (EA) attenuation of sympathoexcitatory cardiovascular reflex responses...
  48. ncbi Electroacupuncture improves restraint stress-induced delay of gastric emptying via central glutaminergic pathways in conscious rats
    Masahiro Iwa
    Department of Surgery, Duke University and Durham Veterans Affairs Medical Center, Surgical Service 112, 508 Fulton Street, NC 27705, USA
    Neurosci Lett 399:6-10. 2006
    ..We investigated the effects of electroacupuncture (EA) at ST-36 (Zusanli; lower limb) on stress-induced delay of gastric emptying...
  49. ncbi Effects of repeated electroacupuncture on beta-endorphin and adrencorticotropic hormone levels in the hypothalamus and pituitary in rats with chronic pain and ovariectomy
    Jun ling Liu
    Department of Physiology, Institute of Acu moxibustion, China Academy of Chinese Medical Sciences, Beijing 100700, China
    Chin J Integr Med 16:315-23. 2010
    To explore the mechanism of electroacupuncture (EA)-induced cumulative analgesic effects on chronic pain in rats with or without ovariectomy (OVX).
  50. ncbi Midbrain vlPAG inhibits rVLM cardiovascular sympathoexcitatory responses during electroacupuncture
    Stephanie C Tjen-A-Looi
    Department of Medicine, Susan Samueli Center for Integrative Medicine, UCI School of Medicine, University of California Irvine, CA 92697 4075, USA
    Am J Physiol Heart Circ Physiol 290:H2543-53. 2006
    ..ventrolateral PAG (vlPAG) provides input to the rostral ventrolateral medulla (rVLM), an important area for electroacupuncture (EA) regulation of sympathetic outflow, we hypothesized that the vlPAG plays a role in the EA-related ..
  51. ncbi Electroacupuncture improves imbalance of autonomic function under restraint stress in conscious rats
    Kenji Imai
    Department of Surgery, Duke University, Durham, North Carolina 27710, USA
    Am J Chin Med 37:45-55. 2009
    ..We have previously shown that electroacupuncture (EA) improves delayed gastric emptying induced by restraint stress in rats...
  52. pmc Electroacupuncture suppresses capsaicin-induced secondary hyperalgesia through an endogenous spinal opioid mechanism
    Hee Young Kim
    Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555 1069, USA
    Pain 145:332-40. 2009
    ..The focus of this study is to examine the analgesic effects of electroacupuncture (EA) on capsaicin-induced secondary hyperalgesia, which represents central sensitization. Capsaicin (0...
  53. ncbi Proteomic analysis of differential protein expression in neuropathic pain and electroacupuncture treatment models
    Ho Joong Sung
    Asan Institute for Life Sciences, Asan Medical Center, Seoul, South Korea
    Proteomics 4:2805-13. 2004
    ..The model was confirmed by behavioral tests. Electroacupuncture (EA) treatment was applied to Zusanli (ST36) of neuropathic pain model to examine the analgesic effect of EA...
  54. pmc TRPV1 expression in acupuncture points: response to electroacupuncture stimulation
    Therese S Abraham
    Department of Obstetrics and Gynecology, David Geffen School of Medicine at University of California at Los Angeles, Harbor UCLA Medical Center, Torrance, CA 90502, USA
    J Chem Neuroanat 41:129-36. 2011
    ..TRPV1) receptor immunoreactivity in the acupuncture points (acupoint), and determine the influences of electroacupuncture (EA) stimulation on TRPV1 expression...
  55. ncbi Low-frequency electro-acupuncture reduces the nociceptive response and the pain mediator enhancement induced by nerve growth factor
    Luigi Aloe
    Institute of Neurobiology and Molecular Medicine, National Research Council, Rome, Italy
    Neurosci Lett 449:173-7. 2009
    ..Our findings indicate that low-frequency EA could be useful as a supportive therapy to reduce NGF-induced side effects, such as hypersensitivity and hyperalgesia, when clinical treatment with NGF is necessary...
  56. ncbi The effects of electroacupuncture on peripheral nerve regeneration in rats
    Motohiro Inoue
    Meiji University of Oriental Medicine, Kyoto, Japan
    Acupunct Med 21:9-17. 2003
    This study was designed to examine the effects of electroacupuncture with direct current (DC) on peripheral nerve regeneration. The left sciatic nerve of 55 7-month-old rats was crushed at the thigh...
  57. ncbi Electroacupuncture pretreatment ameliorates hypergravity-induced impairment of learning and memory and apoptosis of hippocampal neurons in rats
    Shufang Feng
    Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Xi an, Shaanxi Province, China
    Neurosci Lett 478:150-5. 2010
    ..Our previous studies have shown that electroacupuncture (EA) pretreatment can attenuate transient focal cerebral ischemic injury in the rats...
  58. ncbi Electroacupuncture combined with clomipramine enhances antidepressant effect in rodents
    Jin Yu
    Department of Integrative Medicine and Neurobiology, Institute of Acupuncture Research WHO Collaborating Center for Traditional Medicine, Shanghai Medical College, Fudan University, Shanghai 200032, China
    Neurosci Lett 421:5-9. 2007
    The present study was designed to evaluate the antidepressant effect of electroacupuncture (EA) and the potential additive or synergistic effects of EA and clomipramine (CLO, a tricyclic antidepressant) in the mouse forced swimming test (..
  59. ncbi Low-frequency electroacupuncture suppresses carrageenan-induced paw inflammation in mice via sympathetic post-ganglionic neurons, while high-frequency EA suppression is mediated by the sympathoadrenal medullary axis
    Hyun Woo Kim
    Department of Veterinary Physiology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, Seoul 151 742, South Korea
    Brain Res Bull 75:698-705. 2008
    Although the frequency-dependent antinociceptive mechanisms of electroacupuncture (EA) have been well demonstrated, the anti-inflammatory mechanisms that underlie the suppressive effects induced by different frequencies of EA stimulation ..
  60. ncbi Downregulation of electroacupuncture at ST36 on TNF-alpha in rats with ulcerative colitis
    Li Tian
    Department of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi an 710038, Shanxi Province, China
    World J Gastroenterol 9:1028-33. 2003
    To investigate the regulatory effect of electroacupuncture (EA) at Zusanli (ST36) on tumor necrosis factor-alpha (TNF-alpha) in rats with ulcerative colitis (UC), and further elucidate the therapeutic mechanism of EA on UC.
  61. ncbi Electroacupuncture accelerates gastric emptying in association with changes in vagal activity
    Hui Ouyang
    Division of Gastroenterology, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX 77555 0632, USA
    Am J Physiol Gastrointest Liver Physiol 282:G390-6. 2002
    Gastroparesis is a disorder with a lack of treatment options and this study investigated the effect of electroacupuncture on gastric emptying and involved mechanisms...
  62. ncbi CCK(B) receptor antagonist L365,260 potentiates the efficacy to and reverses chronic tolerance to electroacupuncture-induced analgesia in mice
    Cheng Huang
    Department of Physiology, Gannan Medical University, 1 Yixueyuan Road, Ganzhou 341000, PR China
    Brain Res Bull 71:447-51. 2007
    ..work has shown that CCK-8 plays an important role in the development of tolerance to morphine analgesia and electroacupuncture (EA) analgesia in the rat...
  63. ncbi Low-frequency electroacupuncture suppresses zymosan-induced peripheral inflammation via activation of sympathetic post-ganglionic neurons
    Hyun Woo Kim
    Department of Veterinary Physiology, College of Veterinary Medicine and BK21 Program for Veterinary Science, Seoul National University, Seoul, South Korea
    Brain Res 1148:69-75. 2007
    b>Electroacupuncture (EA) is used to treat a variety of inflammatory diseases; however, the neurophysiological mechanisms underlying EA's anti-inflammatory effect remain unclear...
  64. ncbi Excitatory projections from arcuate nucleus to ventrolateral periaqueductal gray in electroacupuncture inhibition of cardiovascular reflexes
    Peng Li
    Department of Medicine, Susan Samueli Center for Integrative Medicine, UCI School of Medicine, University of California Irvine, CA 92697 4075, USA
    Am J Physiol Heart Circ Physiol 290:H2535-42. 2006
    We have shown that the modulatory effect of electroacupuncture (EA) on the blood pressure (BP) response induced by visceral organ stimulation is related to inhibition of cardiovascular neurons in the rostral ventrolateral medulla (rVLM) ..
  65. ncbi Repeated electroacupuncture preconditioning attenuates matrix metalloproteinase-9 expression and activity after focal cerebral ischemia in rats
    Hui Dong
    Department of Anesthesiology, Xijing Hospital, The Fourth Military Medical University, Xi an, China
    Neurol Res 31:853-8. 2009
    This study investigates the effects of electroacupuncture (EA) preconditioning on blood-brain barrier (BBB) integrity and matrix metalloproteinase-9 (MMP-9) expression in subsequent ischemic hemisphere.
  66. pmc Expression of c-Fos in arcuate nucleus induced by electroacupuncture: relations to neurons containing opioids and glutamate
    Zhi Ling Guo
    Susan Samueli Center for Integrative Medicine and Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    Brain Res 1166:65-76. 2007
    b>Electroacupuncture (EA) at the Neiguan-Jianshi acupoints (P5-P6, overlying the median nerve) attenuates sympathoexcitatory reflexes probably through the opioid system...
  67. ncbi Prolonged inhibition of rostral ventral lateral medullary premotor sympathetic neurons by electroacupuncture in cats
    Stephanie C Tjen-A-Looi
    Department of Internal Medicine, University of California at Irvine, Irvine, CA 92697 4075, USA
    Auton Neurosci 106:119-31. 2003
    We have shown that electroacupuncture (EA) at the Neiguan-Jianshi (N-J) acupoints over the median nerve reduces myocardial ischemia by modulating the pressor response induced by application of bradykinin on the gallbladder...
  68. ncbi Effects of electroacupuncture with different frequencies on spinal ionotropic glutamate receptor expression in complete Freund's adjuvant-injected rat
    Byung Tae Choi
    Department of Anatomy, College of Oriental Medicine, Dong Eui University, Busan 614 052, Republic of Korea
    Acta Histochem 107:67-76. 2005
    We investigated expressional changes of spinal glutamate receptors by electroacupuncture (EA) in an inflammatory animal model...
  69. ncbi Characteristics of electroacupuncture-induced analgesia in mice: variation with strain, frequency, intensity and opioid involvement
    Cheng Huang
    Neuroscience Research Institute, Peking University, 38 Xueyuan Road, Beijing 100083, China
    Brain Res 945:20-5. 2002
    The present study was conducted to evaluate the characteristics of electroacupuncture (EA)-induced analgesia in mice...
  70. pmc Responses of opioid and serotonin containing medullary raphe neurons to electroacupuncture
    Zhi Ling Guo
    Susan Samueli Center for Integrative Medicine, Department of Medicine, School of Medicine, University of California, Irvine, CA 92697, USA
    Brain Res 1229:125-36. 2008
    ..We previously have demonstrated that electroacupuncture (EA) at the Neiguan-Jianshi acupoints (P5-P6, overlying the median nerves) attenuates sympathoexcitatory ..
  71. ncbi Modulation of natural killer cell activity affected by electroacupuncture through lateral hypothalamic area in rats
    G S Choi
    Department of East West Medicine, Graduate School, Kyung Hee University, Seoul, South Korea
    Neurosci Lett 329:1-4. 2002
    b>Electroacupuncture (EA) has been reported to modulate natural killer cell (NK cell) activities. Also it is well known that hypothalamus directly mediates the effects of EA on analgesia...
  72. pmc An arcuate-ventrolateral periaqueductal gray reciprocal circuit participates in electroacupuncture cardiovascular inhibition
    Peng Li
    Department of Medicine, Susan Samueli Center for Integrative Medicine, School of Medicine, University of California, Irvine, CA 92697 4075, United States
    Auton Neurosci 158:13-23. 2010
    b>Electroacupuncture (EA) suppresses elevated blood pressure (BP) by activating the arcuate nucleus, ventrolateral periaqueductal gray (vlPAG), and inhibiting cardiovascular sympathetic neurons in the rostral ventrolateral medulla...
  73. ncbi Transcutaneous electrical nerve stimulation for the management of neuropathic pain: the effects of frequency and electrode position on prevention of allodynia in a rat model of complex regional pain syndrome type II
    David L Somers
    Department of Physical Therapy, Duquesne University, 113 Health Sciences Bldg, Pittsburgh, PA 15282 0011, USA
    Phys Ther 86:698-709. 2006
    ..The purpose of this study was to compare the ability of several different stimulation strategies to reduce the development of allodynia...
  74. ncbi The alpha-adrenoceptor mediation of the immunomodulatory effects of electroacupuncture in DNP-KLH immunized mice
    Youngseop Lee
    Department of Physiology, College of Oriental Medicine, Kyung Hee University, Seoul 130 701, Republic of Korea
    Neurosci Lett 423:149-52. 2007
    Our previous study demonstrated that successive electroacupuncture (EA) at ST36 acupoint reduces IgE production in BALB/c mice immunized with 2,4-dinitrophenylated keyhole limpet protein (DNP-KLH) by suppression of the Th2 cell lineage ..
  75. ncbi A comparative study of the effects of electroacupuncture and moxibustion in the gastrointestinal motility of the rat
    Angela Tabosa
    Division of Chinese Medicine and Acupuncture, Department of Orthopedics and Traumatology, Universidade Federal de Sao Paulo UNIFESP, Rua Vergueiro, 2045, cj 1003, Vila Mariana, 04101 000 São Paulo SP, Brazil
    Dig Dis Sci 49:602-10. 2004
    ..rats were immobilized for 20 min and stimulated at either abdominal or hindlimbs acupoints, with either electroacupuncture or moxibustion...
  76. ncbi Improvement in glucose tolerance as a result of enhanced insulin sensitivity during electroacupuncture in spontaneously diabetic Goto-Kakizaki rats
    Naoto Ishizaki
    Division of Acupuncture for Visceral Functions, Department of Clinical Acupuncture and Moxibustion, Meiji University of Integrative Medicine, Hiyoshi cho, Nantan shi, Kyoto 629 0392, Japan
    Metabolism 58:1372-8. 2009
    We studied whether electroacupuncture (EA) applied on the abdomen improved glucose tolerance in the Goto-Kakizaki (GK) rat, a genetic model of type 2 diabetes mellitus...
  77. ncbi Electroacupuncture promotes a decrease in inflammatory response associated with Th1/Th2 cytokines, nitric oxide and leukotriene B4 modulation in experimental asthma
    E R Carneiro
    Department of Physiology, Federal University of Sao Paulo UNIFESP, Sao Paulo, SP, CEP 09972 270, Brazil
    Cytokine 50:335-40. 2010
    Previously, we have shown that electroacupuncture (EA) in rats decreased eosinophil infiltration into the pulmonary tissue (PT) and in the bronchoalveolar lavage (BAL) in an experimental model of asthma...
  78. ncbi The effects of electroacupuncture at the ST36 (Zusanli) acupoint on cancer pain and transient receptor potential vanilloid subfamily 1 expression in Walker 256 tumor-bearing rats
    Zhaodi Zhang
    Department of Anesthesiology, Third Affiliated Hospital of Harbin Medical University, No 6 Baojian Rd, Nangang District, Harbin 150081, China
    Anesth Analg 114:879-85. 2012
    ..b>Electroacupuncture (EA) is an effective method of acupuncture shown to attenuate different kinds of pain such as inflammatory, ..
  79. ncbi Potentiation of Akt and suppression of caspase-9 activations by electroacupuncture after transient middle cerebral artery occlusion in rats
    Shao Jun Wang
    Department of Neurology, Graduate School of Medicine and Dentistry, Okayama University, 2 5 1 Shikatacho, Okayama 700 8558, Japan
    Neurosci Lett 331:115-8. 2002
    b>Electroacupuncture (EA) is an effective curative method for diseases including cerebral ischemia...
  80. ncbi Analgesia induced by 2- or 100-Hz electroacupuncture in the rat tail-flick test depends on the activation of different descending pain inhibitory mechanisms
    Josie R T Silva
    Department of Pharmacology, Faculty of Medicine of Ribeirao Preto USP, Avenida Bandeirantes 3900, Ribeirao Preto, SP, Brazil
    J Pain 12:51-60. 2011
    ..muscarinic (atropine), GABA(A) (bicuculline) and GABA(B) (phaclofen) receptors in blocking 2- or 100-Hz electroacupuncture (EA)-induced analgesia (EAIA) in the rat tail-flick test...
  81. ncbi Involvement of ERK 1/2 activation in electroacupuncture pretreatment via cannabinoid CB1 receptor in rats
    Juan Du
    Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Xi an 710032, China
    Brain Res 1360:1-7. 2010
    Our previous study demonstrated that pretreatment with electroacupuncture (EA) elicited protective effects against transient cerebral ischemia through cannabinoid receptor type 1 receptor (CB1R)...
  82. ncbi Rapid tolerance to focal cerebral ischemia in rats is induced by preconditioning with electroacupuncture: window of protection and the role of adenosine
    Qiang Wang
    Department of Anesthesiology, Xijing Hospital, Fourth Military Medical University, Xi an, 710032 Shaanxi, China
    Neurosci Lett 381:158-62. 2005
    The aim of the present study was to investigate the first protective window of preconditioning with electroacupuncture (EA) against focal cerebral ischemia, and to explore whether adenosine is involved in the rapid tolerance phenomenon...
  83. ncbi Low-frequency electroacupuncture and physical exercise decrease high muscle sympathetic nerve activity in polycystic ovary syndrome
    Elisabet Stener-Victorin
    Institute of Neuroscience and Physiology, Dept of Physiology, Sahlgrenska Academy, Univ of Gothenburg, Box 434, SE 405 30 Goteborg, Sweden
    Am J Physiol Regul Integr Comp Physiol 297:R387-95. 2009
    ..Animal studies support the concept that low-frequency electroacupuncture (EA) and physical exercise, via stimulation of ergoreceptors and somatic afferents in the muscles, may ..
  84. ncbi The central serotonergic system mediates the analgesic effect of electroacupuncture on ZUSANLI (ST36) acupoints
    Fang Chia Chang
    Neuroscience Laboratory, Department of Neurology, China Medical University Hospital, Taichung, Taiwan ROC
    J Biomed Sci 11:179-85. 2004
    Evidence in the past decade indicates that the mechanisms of anti-nociception of electroacupuncture (EAc) involve actions of neuropeptides (i.e., enkephalin and endorphin) and monoamines (i.e...
  85. pmc Functional neuroanatomical investigation of vision-related acupuncture point specificity--a multisession fMRI study
    Jian Kong
    Department of Psychiatry, Massachusetts General Hospital, Charlestown, Massachusetts, USA
    Hum Brain Mapp 30:38-46. 2009
    ..In this study, we used a multiple-session experiment to test whether electroacupuncture stimulation at two TCM vision-related acupoints, UB 60 and GB 37, located on the leg, could produce fMRI ..
  86. ncbi Impact of electro-acupuncture and physical exercise on hyperandrogenism and oligo/amenorrhea in women with polycystic ovary syndrome: a randomized controlled trial
    Elizabeth Jedel
    Osher Center for Integrative Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden
    Am J Physiol Endocrinol Metab 300:E37-45. 2011
    ..Low-frequency EA was superior to physical exercise and may be useful for treating hyperandrogenism and oligo/amenorrhea...
  87. ncbi Long-term high-frequency electro-acupuncture stimulation prevents neuronal degeneration and up-regulates BDNF mRNA in the substantia nigra and ventral tegmental area following medial forebrain bundle axotomy
    Xi Bin Liang
    Neuroscience Research Institute, Peking University, 38 Xueyuan Road, Beijing 100083, PR China
    Brain Res Mol Brain Res 108:51-9. 2002
    b>Electroacupuncture (EA) has been used in China for many years to treat Parkinson's disease (PD) with reportedly effective results. However, the physiological and biological mechanism behind its effectiveness is still unknown...
  88. pmc Electroacupuncture suppresses hyperalgesia and spinal Fos expression by activating the descending inhibitory system
    Aihui Li
    Center for Integrative Medicine, School of Medicine, University of Maryland, 20 Penn Street, Baltimore, MD 21201, USA
    Brain Res 1186:171-9. 2007
    Although electroacupuncture (EA) is widely used to treat pain, its mechanisms have not been completely understood. The present study investigated the descending inhibitory system involvement in EA action...
  89. ncbi Brain substrates activated by electroacupuncture of different frequencies (I): Comparative study on the expression of oncogene c-fos and genes coding for three opioid peptides
    H F Guo
    Neuroscience Research Center, Beijing Medical University, People s Republic of China
    Brain Res Mol Brain Res 43:157-66. 1996
    Low and high frequency electroacupuncture (EA)-produced analgesia have been shown to be mediated by different brain substrates and different opioid peptides...
  90. ncbi Electroacupuncture counteracts the development of thermal hyperalgesia and the alteration of nerve growth factor and sensory neuromodulators induced by streptozotocin in adult rats
    L Manni
    Institute of Neurobiology and Molecular Medicine, National Research Council, Rome, Italy
    Diabetologia 54:1900-8. 2011
    ..b>Electroacupuncture has been proved effective in the treatment of human neuropathic pain as well as in modulating NGF production/..
  91. ncbi Repeated electroacupuncture attenuating of apelin expression and function in the rostral ventrolateral medulla in stress-induced hypertensive rats
    Cheng rong Zhang
    Department of Physiology and Pathophysiology, Shanghai Medical College of Fudan University, 138 Yixueyuan Road, Shanghai 200032, China
    Brain Res Bull 97:53-62. 2013
    ..In addition, repetitive electroacupuncture (EA) stimulation at the Zusanli (ST-36) acupoint attenuated hypertension and apelin expression in the RVLM ..
  92. ncbi Electroacupuncture elicits dual effects: stimulation of delayed gastric emptying and inhibition of accelerated colonic transit induced by restraint stress in rats
    Masahiro Iwa
    Department of Surgery, Duke University and Durham Veterans Affairs Medical Center, Durham, North Carolina 27705, USA
    Dig Dis Sci 51:1493-500. 2006
    ..We investigated the effects of electroacupuncture (EA) at ST-36 (Zusanli; lower limb) on stress-induced alteration of GI motor activities...
  93. pmc Electroacupuncture modulates vlPAG release of GABA through presynaptic cannabinoid CB1 receptors
    Liang Wu Fu
    Department of Medicine, University of California, Irvine, CA 92697, USA
    J Appl Physiol (1985) 106:1800-9. 2009
    Previous studies have demonstrated that electroacupuncture (EA) attenuates sympathoexcitatory reflex responses by activating a long-loop pathway involving the hypothalamic arcuate nucleus (ARC), midbrain ventrolateral periaqueductal gray (..
  94. pmc Involvement of spinal serotonin receptors in electroacupuncture anti-hyperalgesia in an inflammatory pain rat model
    Yu Zhang
    Center for Integrative Medicine, School of Medicine, University of Maryland, 685 W Baltimore Street, MSTF Rm 8 22, Baltimore, MD 21201, USA
    Neurochem Res 36:1785-92. 2011
    We previously showed that electroacupuncture (EA) activates medulla-spinal serotonin-containing neurons...
  95. ncbi Ovarian blood flow responses to electro-acupuncture stimulation at different frequencies and intensities in anaesthetized rats
    Elisabet Stener-Victorin
    Department of Physiology, Institute for the Health of Women and Children, Goteborg University, Box 432, SE 405 30 Goteborg, Sweden
    Auton Neurosci 108:50-6. 2003
    ....
  96. ncbi Effect of pre-electroacupuncture on p38 and c-Fos expression in the spinal dorsal horn of rats suffering from visceral pain
    Ke da Xu
    Department of Digestive Diseases, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China
    Chin Med J (Engl) 123:1176-81. 2010
    Acupuncture is an effective way to relieve pain, but the mechanism by which electroacupuncture (EA) decreases the visceral pain state still remains unclear...
  97. ncbi Electroacupuncture enhances striatal neurogenesis in adult rat brains after a transient cerebral middle artery occlusion
    Zeng Jin Yang
    State Key Laboratory of Medical Neurobiology, Shanghai Medical College of Fudan University, Shanghai 200032, P R China
    Acupunct Electrother Res 30:185-99. 2005
    In this study, we investigated the effects of electroacupuncture (EA) on ischemia-induced neurogenesis in the striatum of adult rat brains with a 30-minute middle cerebral artery occlusion...
  98. ncbi Effect of electroacupuncture on the stress-induced changes in brain-derived neurotrophic factor expression in rat hippocampus
    Su Jin Yun
    Graduate School of East West Medical Science, Kyung Hee University, 1 Seochun, Yong In 449 701, South Korea
    Neurosci Lett 318:85-8. 2002
    ..The objective of this study was to examine whether electroacupuncture (EA) stimulation can influence BDNF expression in the hippocampus of rats exposed to immobilization stress...
  99. ncbi Electroacupuncture enhances cell proliferation and neuronal differentiation in young rat brains
    Jianfeng Gao
    Department of Pediatrics, The Third Affiliated Hospital of Zhengzhou University, Kangfuqain Street 7, Zhengzhou 450052, China
    Neurol Sci 32:369-74. 2011
    To investigate the effect of electroacupuncture on cell proliferation and differentiation in young rat hippocampus, postnatal day-14 rats were assigned randomly to control, ketamine anesthesia, nonacupoint, or acupoint electroacupuncture ..
  100. ncbi Electroacupuncture pretreatment prevents cognitive impairment induced by limb ischemia-reperfusion via inhibition of microglial activation and attenuation of oxidative stress in rats
    Ye Chen
    Department of Traditional Chinese Medicine, Affiliated Hospital of Luzhou Medical College, Luzhou, PR China
    Brain Res 1432:36-45. 2012
    ..2) potential players in the mechanistic pathway mediating such effects, and (3) possible benefits of electroacupuncture (EA) pretreatment at Baihui (GV20), Yanglingquan (GB34), Taichong (LR3), Zusanli (ST36) and Xuehai (SP10) ..
  101. ncbi Involvement of peripheral opioid mechanisms in electroacupuncture analgesia
    Grant G Zhang
    Complementary Medicine Program, University of Maryland School of Medicine, Baltimore, USA
    Explore (NY) 1:365-71. 2005
    ..This study aimed to investigate the possibility of electroacupuncture (EA)-mediated peripheral opioid release...

Research Grants29

  1. Mechanims of CNS Autonomic Regulation by EA
    John C Longhurst; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Acupuncture and its potent alternative, electroacupuncture (EA), are accepted treatments for pain, nausea and vomiting. Small trails further suggest that EA can lower elevated blood pressure...
  2. Functional Bowel Disorders in Chinese Medicine
    Brian Berman; Fiscal Year: 2009
    ..Our previous studies have revealed that electroacupuncture (EA) produces prolonged anti-inflammatory and anti-hyperalgesic effects in rats with complete Freund's ..
  3. Effects of Advanced EA on Hypertension: Role of nNOS-NO in the Dorsal Medulla
    Sheng Xing Ma; Fiscal Year: 2010
    ..nucleus tractus solitarius (NTS) receive somatosensory afferent inputs from the hindlimb, and low-frequency electroacupuncture (EA) stimulation of hindlimb acupoint ST36 produces long-lasting sympathoinhibition and arterial blood ..
  4. Modulating Ocular/Retinal Blood Flow and Visual Function in Retinitis Pigmentosa
    Ava K Bittner; Fiscal Year: 2013
    ..The potential for a beneficial effect on visual function in RP following electroacupuncture and/or transcorneal electrical stimulation (TES) is suggested by research on physiological changes in the ..
  5. Neural Substrates of Electroacupuncture in Cardiovascular Control
    STEPHANIE CHEE YEE TJEN-A-LOOI; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): We have investigated the mechanisms by which acupuncture, particularly electroacupuncture (EA) regulates blood pressure (BP)...
  6. Transcutaneous electroacupuncture for gastroparesis
    Jiande Chen; Fiscal Year: 2010
    ..Common symptoms of gastroparesis include nausea, vomiting, early satiety and abdominal bloating. Electroacupuncture (EA) is a combined procedure with acupuncture and electrical current stimulation instead of manual ..
  7. Endogenous Mechanisms of Electroacupuncture
    Carolyn A Fairbanks; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Acupuncture and electroacupuncture have been increasingly adopted in North America as a complement to pharmacotherapy for chronic pain over the last twenty years (1997 NIH Consensus Statement on ..
  8. Effects of Acupuncture-Induced nNOS-NO in Dorsal Medulla on Sensory Neuropathy
    Sheng Xing Ma; Fiscal Year: 2010
    ..Hyperalgesia and hypersensitivity to temperature/ pressure in ZDF rats are improved by low-frequency electroacupuncture (EA) stimulation of acupoint ST36...
  9. Central Effects of Acupuncture: Acupoint Specificity
    Ji Fang; Fiscal Year: 2009
    ..Whole brain fMRI is performed during electroacupuncture at St36 (Zusanli),Gb34 (Yanglingquan) and a sham point on the leg, and at Li11(Quchi) on the elbow...
  10. Effects of acupuncture on chemotherapy-induced pain
    Ruixin Zhang; Fiscal Year: 2009
    ..The objective of this study is to evaluate the effects and mechanisms of electroacupuncture (EA) on a paclitaxel-induced CIP rat model with persistent pain for 5 months...
  11. Neural Mechanisms Underlying Acupuncture Analgesia
    Jin Chung; Fiscal Year: 2007
    ..The present proposal describes a model of electroacupuncture (EA)- induced analgesia in ankle sprain pain...
  12. Osteopuncture for OA-Associated Knee Pain & Disability
    Debra Weiner; Fiscal Year: 2005
    ..Periosteal electroacupuncture (osteopuncture) is a more potent modality than traditional Chinese acupuncture (TCA), with which we have had ..
  13. THE USE OF ELECTROACUPUNCTURE TO MODULATE AROUSAL
    Edgar Garcia Rill; Fiscal Year: 2002
    ..We have preliminary data suggesting that electroacupuncture (EA) applied at three specific points may modulate the manifestation of the P50 potential...
  14. ACUPUNTURE AND HYPERTENSION: EFFICACY AND MECHANISMS
    Norman Kaplan; Fiscal Year: 2000
    ..conscious humans provides a new opportunity to test this novel mechanistic hypothesis in patients undergoing electroacupuncture, a modification of the ancient technique which provides a quantifiable and reproducible stimulus to human ..
  15. Functional Impact of PENS for 65+ Chronic Low Back Pain
    Debra Weiner; Fiscal Year: 2006
    ..explore the utility of percutaneous electrical nerve stimulation (PENS), a neuroanatomically guided form of electroacupuncture, as a safe non-pharmacologic analgesic alternative for the older adult with CLBP...
  16. NITRIC OXIDE ON ACUPUNCTURE SIGNALS IN GRACILE NUCLEUS
    Sheng Xing Ma; Fiscal Year: 2001
    Low-frequency electroacupuncture (EA) stimulation of hindlimb acupoints produces long-lasting sympathoinhibition in humans and rats...
  17. Electroacupuncture for Major Depression: A Pilot Study
    Benoit Mulsant; Fiscal Year: 2004
    ..It will use a randomized parallel-group design to compare the safety, efficacy, and tolerability of electroacupuncture (EA) and sham electroacupuncture (SA) for the treatment of major depression...
  18. CENTER FOR ALTERNATIVE MEDICINE RESEARCH OF ARTHRITIS
    Brian Berman; Fiscal Year: 2003
    ..2) the effectiveness of mind/body therapies for fibromyalgia; 3) the mechanism of action and effects of electroacupuncture on persistent pain & inflammation; and 4) the mechanism of action of a herbal combination with ..
  19. To study the neuronal mechanism of acupunture analgesia
    Albert Leung; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  20. The Status and Future of Acupuncture Research: 10 Years Post-NIH Consensus Confer
    Lixing Lao; Fiscal Year: 2007
    ..The proposed conference will do so. [unreadable] [unreadable] [unreadable] [unreadable]..
  21. Effects of Acupuncture on Bone Cancer Pain in Mice
    Ruixin Zhang; Fiscal Year: 2004
    ..We propose to use this model to evaluate the effects and mechanisms of electroacupuncture (EA) at acupoint G30 (Huan Tiao) on femoral cancer pain...
  22. Patient-Provider Interaction & Response to Acupuncture
    Maria Suarez Almazor; Fiscal Year: 2005
    ..In addition there will be a natural control group (waiting list group), in which patients will be offered acupuncture three months after study entry. ..
  23. Consistency of TCM RA Diagnosis and Herbal Prescriptions
    Grant Zhang; Fiscal Year: 2002
    ..More importantly, this study will be broadly applicable to clinical TCM research in general, and may help to establish a stronger methodological model for the evaluation of individualized treatment. ..
  24. Treatment adherence in minorities with rheumatic disease
    Maria Suarez Almazor; Fiscal Year: 2006
    ....
  25. Cognitive Behavioral Determinants in Knee Replacement
    Maria Suarez Almazor; Fiscal Year: 2007
    ..The intervention will be based on cognitive behavioral strategies. ..
  26. Acupuncture For Infertility Patients: The Effect On IVF
    Grant Zhang; Fiscal Year: 2007
    ..Result obtained from the study will provide necessary information for a larger, definitive study, as well as knowledge regarding the broad mechanism of acupuncture on female reproductive function. [unreadable] [unreadable]..
  27. Sensory-enhanced motor training for hemiparetic arm/hand
    Wen Liu; Fiscal Year: 2004
    ..The effect of enhanced sensory inputs will be determined through the comparison of outcomes of the two training programs. ..
  28. Treatment of Older Patients with Early Breast Cancer
    Arash Naeim; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  29. Acupuncture and Low Back Pain during Pregnancy
    Shu Ming Wang; Fiscal Year: 2007
    ..abstract_text> ..