heart catheterization

Summary

Summary: Procedure which includes placement of catheter, recording of intracardiac and intravascular pressure, obtaining blood samples for chemical analysis, and cardiac output measurement, etc. Specific angiographic injection techniques are also involved.

Top Publications

  1. ncbi Transcatheter versus surgical aortic-valve replacement in high-risk patients
    Craig R Smith
    Columbia University Medical Center New York Presbyterian Hospital, New York, NY 10032, USA
    N Engl J Med 364:2187-98. 2011
  2. ncbi Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery
    Martin B Leon
    Columbia University Medical Center NewYork Presbyterian Hospital, New York, NY 10032, USA
    N Engl J Med 363:1597-607. 2010
  3. ncbi Two-year outcomes after transcatheter or surgical aortic-valve replacement
    Susheel K Kodali
    Columbia University Medical Center and New York Presbyterian Hospital, New York, NY 10032, USA
    N Engl J Med 366:1686-95. 2012
  4. ncbi A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease
    Bernard Iung
    Cardiology Department, Bichat Hospital, AP HP, Paris, France
    Eur Heart J 24:1231-43. 2003
  5. ncbi Prognostic value of right ventricular mass, volume, and function in idiopathic pulmonary arterial hypertension
    Serge A van Wolferen
    Department of Pulmonary Diseases, Institute for Cardiovascular Research ICaR VU, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Eur Heart J 28:1250-7. 2007
  6. ncbi Registry of transcatheter aortic-valve implantation in high-risk patients
    Martine Gilard
    Centre Hospitalier Universitaire CHU Brest, Brest, France
    N Engl J Med 366:1705-15. 2012
  7. ncbi Early detection of pulmonary arterial hypertension in systemic sclerosis: a French nationwide prospective multicenter study
    Eric Hachulla
    Hopital Claude Huriez, Lille, France
    Arthritis Rheum 52:3792-800. 2005
  8. pmc Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium
    Martin B Leon
    Columbia University Medical Center, Center for Interventional Vascular Therapy, 173 Fort Washington Avenue, Heart Center, New York, NY 10032, USA
    Eur Heart J 32:205-17. 2011
  9. ncbi Transcatheter aortic valve implantation for the treatment of severe symptomatic aortic stenosis in patients at very high or prohibitive surgical risk: acute and late outcomes of the multicenter Canadian experience
    Josep Rodes-Cabau
    Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada
    J Am Coll Cardiol 55:1080-90. 2010
  10. ncbi Transcatheter aortic valve implantation: lessons from the learning curve of the first 270 high-risk patients
    Ronen Gurvitch
    Department of Cardiology and Cardiothoracic Surgery, St Paul s Hospital, University of British Columbia, Vancouver, Canada
    Catheter Cardiovasc Interv 78:977-84. 2011

Detail Information

Publications322 found, 100 shown here

  1. ncbi Transcatheter versus surgical aortic-valve replacement in high-risk patients
    Craig R Smith
    Columbia University Medical Center New York Presbyterian Hospital, New York, NY 10032, USA
    N Engl J Med 364:2187-98. 2011
    ..However, the two procedures have not been compared in a randomized trial involving high-risk patients who are still candidates for surgical replacement...
  2. ncbi Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery
    Martin B Leon
    Columbia University Medical Center NewYork Presbyterian Hospital, New York, NY 10032, USA
    N Engl J Med 363:1597-607. 2010
    ..Recently, transcatheter aortic-valve implantation (TAVI) has been suggested as a less invasive treatment for high-risk patients with aortic stenosis...
  3. ncbi Two-year outcomes after transcatheter or surgical aortic-valve replacement
    Susheel K Kodali
    Columbia University Medical Center and New York Presbyterian Hospital, New York, NY 10032, USA
    N Engl J Med 366:1686-95. 2012
    ..However, longer-term follow-up is necessary to determine whether TAVR has prolonged benefits...
  4. ncbi A prospective survey of patients with valvular heart disease in Europe: The Euro Heart Survey on Valvular Heart Disease
    Bernard Iung
    Cardiology Department, Bichat Hospital, AP HP, Paris, France
    Eur Heart J 24:1231-43. 2003
    ..To identify the characteristics, treatment, and outcomes of contemporary patients with valvular heart disease (VHD) in Europe, and to examine adherence to guidelines...
  5. ncbi Prognostic value of right ventricular mass, volume, and function in idiopathic pulmonary arterial hypertension
    Serge A van Wolferen
    Department of Pulmonary Diseases, Institute for Cardiovascular Research ICaR VU, VU University Medical Center, De Boelelaan 1117, 1081 HV Amsterdam, The Netherlands
    Eur Heart J 28:1250-7. 2007
    ..This study investigated the relationship between right ventricular (RV) structure and function and survival in idiopathic pulmonary arterial hypertension (IPAH)...
  6. ncbi Registry of transcatheter aortic-valve implantation in high-risk patients
    Martine Gilard
    Centre Hospitalier Universitaire CHU Brest, Brest, France
    N Engl J Med 366:1705-15. 2012
    ..We report the results of a prospective multicenter study of the French national transcatheter aortic-valve implantation registry, FRANCE 2...
  7. ncbi Early detection of pulmonary arterial hypertension in systemic sclerosis: a French nationwide prospective multicenter study
    Eric Hachulla
    Hopital Claude Huriez, Lille, France
    Arthritis Rheum 52:3792-800. 2005
    ..on the method and criteria for optimal screening, we sought to develop an algorithm based on symptoms, Doppler echocardiography, and right heart catheterization (RHC) for application to a nationwide multicenter SSc population in France.
  8. pmc Standardized endpoint definitions for transcatheter aortic valve implantation clinical trials: a consensus report from the Valve Academic Research Consortium
    Martin B Leon
    Columbia University Medical Center, Center for Interventional Vascular Therapy, 173 Fort Washington Avenue, Heart Center, New York, NY 10032, USA
    Eur Heart J 32:205-17. 2011
    ..To make these consensus definitions accessible to all stakeholders in TAVI clinical research through a peer reviewed publication, on behalf of the public health...
  9. ncbi Transcatheter aortic valve implantation for the treatment of severe symptomatic aortic stenosis in patients at very high or prohibitive surgical risk: acute and late outcomes of the multicenter Canadian experience
    Josep Rodes-Cabau
    Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada
    J Am Coll Cardiol 55:1080-90. 2010
    ....
  10. ncbi Transcatheter aortic valve implantation: lessons from the learning curve of the first 270 high-risk patients
    Ronen Gurvitch
    Department of Cardiology and Cardiothoracic Surgery, St Paul s Hospital, University of British Columbia, Vancouver, Canada
    Catheter Cardiovasc Interv 78:977-84. 2011
    ..Transcatheter aortic valve implantation (TAVI) is a rapidly evolving strategy for therapy of aortic stenosis. We describe the effect of the learning curve from the first 270 high-risk patients in Vancouver, Canada...
  11. ncbi One-year outcomes of cohort 1 in the Edwards SAPIEN Aortic Bioprosthesis European Outcome (SOURCE) registry: the European registry of transcatheter aortic valve implantation using the Edwards SAPIEN valve
    Martyn Thomas
    Director of Cardiovascular Services, Cardiology Department, St Thomas Hospital, Westminster Bridge Rd, London, UK
    Circulation 124:425-33. 2011
    ..Transcatheter aortic valve implantation was developed to provide a therapeutic option for patients considered to be ineligible for, and to mitigate mortality and morbidity associated with, high-risk surgical aortic valve replacement...
  12. ncbi Transcatheter aortic-valve replacement for inoperable severe aortic stenosis
    Raj R Makkar
    Cedars Sinai Heart Institute, Los Angeles, USA
    N Engl J Med 366:1696-704. 2012
    ..Transcatheter aortic-valve replacement (TAVR) is the recommended therapy for patients with severe aortic stenosis who are not suitable candidates for surgery. The outcomes beyond 1 year in such patients are not known...
  13. ncbi Transcatheter aortic valve implantation: first results from a multi-centre real-world registry
    Ralf Zahn
    Abteilung fur Kardiologie, Herzzentrum Ludwigshafen, Bremserstrasse 79, Ludwigshafen, Germany
    Eur Heart J 32:198-204. 2011
    ..We report the first results of the prospective multi-centre German Transcatheter Aortic Valve Interventions-Registry...
  14. ncbi Echocardiographic assessment of pulmonary hypertension in patients with advanced lung disease
    Selim M Arcasoy
    Division of Pulmonary, Allergy and Critical Care, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    Am J Respir Crit Care Med 167:735-40. 2003
    ..of 374 lung transplant candidates, the performance characteristics of echocardiography compared with right heart catheterization in the determination of systolic pulmonary artery pressure and diagnosis of pulmonary hypertension were ..
  15. ncbi Transcatheter aortic valve implantation: early results of the FRANCE (FRench Aortic National CoreValve and Edwards) registry
    Helene Eltchaninoff
    Cardiology Department, Charles Nicolle Hospital, University of Rouen INSERM U644, 1 rue de Germont, Rouen Cedex, France
    Eur Heart J 32:191-7. 2011
    ....
  16. ncbi Transcatheter aortic valve implantation: 3-year outcomes of self-expanding CoreValve prosthesis
    Gian Paolo Ussia
    Interventional Structural and Congenital Heart Disease Programme, Invasive Cardiology Division of Cardiology, Ferrarotto Hospital, University of Catania, Catania, Italy
    Eur Heart J 33:969-76. 2012
    ..We sought to assess 3-year clinical and echocardiographic outcomes of patients undergoing TAVI with the third generation CoreValve prosthesis (Medtronic Incorporation, MN, USA)...
  17. pmc Characterization of connective tissue disease-associated pulmonary arterial hypertension from REVEAL: identifying systemic sclerosis as a unique phenotype
    Lorinda Chung
    VA Palo Alto Health Care System, Palo Alto, CA 94304, USA
    Chest 138:1383-94. 2010
    ..is the largest US cohort of patients with pulmonary arterial hypertension (PAH) confirmed by right-sided heart catheterization (RHC), providing a more comprehensive subgroup characterization than previously possible...
  18. ncbi Multimodal assessment of the aortic annulus diameter: implications for transcatheter aortic valve implantation
    David Messika-Zeitoun
    INSERM, U698, University Paris 7, Paris, France
    J Am Coll Cardiol 55:186-94. 2010
    ....
  19. ncbi Improvements in transcatheter aortic valve implantation outcomes in lower surgical risk patients: a glimpse into the future
    Ruediger Lange
    German Heart Center, Lazarette Strasse 36, Munich, Germany
    J Am Coll Cardiol 59:280-7. 2012
    ..The purpose of this study was to investigate the evolution of patient selection criteria for transcatheter aortic valve implantation (TAVI) and its impact on clinical outcomes...
  20. pmc Prevalence and outcome in systemic sclerosis associated pulmonary arterial hypertension: application of a registry approach
    D Mukerjee
    Department of Rheumatology, Royal Free Hospital, Pond Street, London NW3 2QG, UK
    Ann Rheum Dis 62:1088-93. 2003
    ..To determine the prevalence of systemic sclerosis associated pulmonary arterial hypertension (SScPAH), evaluate outcome, and identify predictors of mortality in a large patient cohort...
  21. ncbi Adverse effects associated with transcatheter aortic valve implantation: a meta-analysis of contemporary studies
    Prateek J Khatri
    University of Toronto, Institute for Clinical Evaluative Sciences, Toronto, Ontario, Canada
    Ann Intern Med 158:35-46. 2013
    ....
  22. ncbi Comparison of two-dimensional and three-dimensional imaging techniques for measurement of aortic annulus diameters before transcatheter aortic valve implantation
    Ertunc Altiok
    Department of Cardiology, University Hospital RWTH Aachen, Aachen, Germany
    Heart 97:1578-84. 2011
    ..This study sought to compare different 2D and 3D imaging techniques and determine the accuracy of 3D transoesophageal echocardiography (TEE) for accurate analysis of aortic annulus dimensions...
  23. ncbi Procedural, 30-day and one year outcome following CoreValve or Edwards transcatheter aortic valve implantation: results of the Belgian national registry
    Johan M Bosmans
    Department of Cardiology and Cardiac Surgery, Antwerp University Hospital, Antwerp, Belgium
    Interact Cardiovasc Thorac Surg 12:762-7. 2011
    ..This mid-term mortality was mainly related to age-related, non-cardiac complications...
  24. ncbi Transcranial Doppler sound detection of cerebral microembolism during transapical aortic valve implantation
    T Drews
    Deutsches Herzzentrum Berlin, Berlin, Germany
    Thorac Cardiovasc Surg 59:237-42. 2011
    ..However, whether it usually occurs, how often, and its clinical relevance are not known. We report the results of ultrasound microembolic signal detection in the middle cerebral artery during the procedure...
  25. ncbi Cerebral embolism following transcatheter aortic valve implantation: comparison of transfemoral and transapical approaches
    Josep Rodes-Cabau
    Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada
    J Am Coll Cardiol 57:18-28. 2011
    ....
  26. ncbi Standardized endpoint definitions for Transcatheter Aortic Valve Implantation clinical trials: a consensus report from the Valve Academic Research Consortium
    Martin B Leon
    Columbia University Medical Center, New York, New York 10032, USA
    J Am Coll Cardiol 57:253-69. 2011
    ..To make these consensus definitions accessible to all stakeholders in TAVI clinical research through a peer reviewed publication, on behalf of the public health...
  27. ncbi Assessment of the aortic annulus by multislice computed tomography, contrast aortography, and trans-thoracic echocardiography in patients referred for transcatheter aortic valve implantation
    Apostolos Tzikas
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    Catheter Cardiovasc Interv 77:868-75. 2011
    ....
  28. ncbi The German Aortic Valve Registry (GARY): a nationwide registry for patients undergoing invasive therapy for severe aortic valve stenosis
    A Beckmann
    Deutsche Gesellschaft für Thorax, Herz und Gefäßchirurgie DGTHG, Langenbeck Virchow Haus Luisenstrasse 58 59, Berlin, Germany
    Thorac Cardiovasc Surg 60:319-25. 2012
    ..In contrast to randomized controlled trials, GARY is a prospective, controlled, 5-year observational multicenter registry, and a real world investigation with only one exclusion criterion, the absence of patients' written consent...
  29. ncbi Beyond the short-term: clinical outcome and valve performance 2 years after transcatheter aortic valve implantation in 227 patients
    Sabine Bleiziffer
    Clinic for Cardiovascular Surgery, German Heart Center Munich, Germany
    J Thorac Cardiovasc Surg 143:310-7. 2012
    ..We report on 2-year follow-up clinical and echocardiographic results after transcatheter aortic valve implantation in 227 patients...
  30. ncbi Transcatheter aortic valve implantation for high-risk patients with severe aortic stenosis: A systematic review
    Tristan D Yan
    Department of Cardiothoracic Surgery, The University of Sydney, Royal Prince Alfred Hospital, Sydney 2050, Australia
    J Thorac Cardiovasc Surg 139:1519-28. 2010
    ..The present systematic review objectively assessed the safety and clinical effectiveness of transcatheter aortic valve implantation for patients at high surgical risk with severe aortic stenosis...
  31. pmc Low diagnostic yield of elective coronary angiography
    Manesh R Patel
    Duke Clinical Research Institute, Duke University, Durham, NC 27715, USA
    N Engl J Med 362:886-95. 2010
    ..We determined patterns of noninvasive testing and the diagnostic yield of catheterization among patients with suspected coronary artery disease in a contemporary national sample...
  32. ncbi Permanent pacemaker insertion after CoreValve transcatheter aortic valve implantation: incidence and contributing factors (the UK CoreValve Collaborative)
    M Z Khawaja
    UK CoreValve Collaborative, Sussex Cardiac Centre, Brighton and Sussex University Hospital Trust, Eastern Road, Brighton, East Sussex, BN2 5BE, UK
    Circulation 123:951-60. 2011
    ..We assessed the UK incidence of permanent pacing within 30 days of CoreValve implantation and formulated an anatomic and electrophysiological model...
  33. ncbi Percutaneous transarterial aortic valve implantation: what do we know?
    John Webb
    St Paul s Hospital, University of British Columbia, 1081 Burrard Street, Vancouver, BC, Canada
    Eur Heart J 32:140-7. 2011
    ..Nevertheless considerable work needs to be done before the indications for TAVI are expanded into lower risk groups. We review what is currently known about percutaneous transarterial implantation of the aortic valve...
  34. ncbi Aortic annulus evaluation in transcatheter aortic valve implantation
    Andrea Hutter
    Clinic for Cardiovascular Surgery, German Heart Centre Munich, Munich, Germany
    Catheter Cardiovasc Interv 76:1009-19. 2010
    ..We compared the annulus diameters measured by transthoracic echocardiography (TTE), transesophageal echocardiography (TEE), and dual-source computed tomography (DSCT) before transcatheter aortic valve implantation (TAVI)...
  35. pmc Acute kidney injury following transcatheter aortic valve implantation: predictive factors, prognostic value, and comparison with surgical aortic valve replacement
    Rodrigo Bagur
    Quebec Heart and Lung Institute, Laval University, Quebec City, Quebec, Canada G1V 4G5
    Eur Heart J 31:865-74. 2010
    ..surgical aortic valve replacement (SAVR) in patients with pre-procedural chronic kidney disease (CKD)...
  36. ncbi Contrast enhanced-cardiovascular magnetic resonance imaging in patients with pulmonary hypertension
    Kevin G Blyth
    Scottish Pulmonary Vascular Unit, Level 8, Western Infirmary, Glasgow G11 6NT, UK
    Eur Heart J 26:1993-9. 2005
    ..To determine the presence and extent of delayed contrast enhancement (DCE) in patients with pulmonary hypertension (PHT) using contrast enhanced-cardiovascular magnetic resonance imaging (ce-CMR)...
  37. ncbi Transcatheter valve implantation for patients with aortic stenosis: a position statement from the European Association of Cardio-Thoracic Surgery (EACTS) and the European Society of Cardiology (ESC), in collaboration with the European Association of Percu
    Alec Vahanian
    Hopital Bichat, Paris, France
    Eur Heart J 29:1463-70. 2008
    ..To critically review the available transcatheter aortic valve implantation techniques and their results, as well as propose recommendations for their use and development...
  38. ncbi Comparison between Society of Thoracic Surgeons score and logistic EuroSCORE for predicting mortality in patients referred for transcatheter aortic valve implantation
    Itsik Ben-Dor
    Interventional Cardiology, Washington Hospital Center, Washington, DC 20010, USA
    Cardiovasc Revasc Med 12:345-9. 2011
    ..We aimed to examine the correlation between STS and logistic EuroSCOREs and their performance characteristics in patients referred for TAVI...
  39. pmc One year follow-up of the multi-centre European PARTNER transcatheter heart valve study
    Thierry Lefevre
    Institut Hospitalier Jacques Cartier, 6 avenue du Noyer Lambert, Massy, France
    Eur Heart J 32:148-57. 2011
    ..Transcatheter aortic valve implantation (TAVI) has emerged as a new therapeutic option in high-risk patients with severe aortic stenosis...
  40. ncbi Noninvasively assessed pulmonary artery stiffness predicts mortality in pulmonary arterial hypertension
    C Tji Joong Gan
    Department of Pulmonary Diseases, VU University Medical Center, De Boelelaan 1117, PO Box 7057, 1007 MB Amsterdam, The Netherlands
    Chest 132:1906-12. 2007
    ....
  41. ncbi Noninvasive evaluation of the aortic root with multislice computed tomography implications for transcatheter aortic valve replacement
    Laurens F Tops
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, Leiden, The Netherlands
    JACC Cardiovasc Imaging 1:321-30. 2008
    ..In the present study, the anatomy of the aortic root was assessed noninvasively with multislice computed tomography (MSCT)...
  42. ncbi Routine early angioplasty after fibrinolysis for acute myocardial infarction
    Warren J Cantor
    Southlake Regional Health Centre, Newmarket, ON, Canada
    N Engl J Med 360:2705-18. 2009
    ..The role and optimal timing of routine PCI after fibrinolysis have not been established...
  43. ncbi Early and late complications associated with transcatheter occlusion of secundum atrial septal defect
    Massimo Chessa
    Pediatric Cardiology, Istituto Policlinico San Donato, San Donato Milanese, Italy
    J Am Coll Cardiol 39:1061-5. 2002
    ..The goal of this study was to report the early and late complications experienced in atrial septal defect (ASD) transcatheter closure...
  44. ncbi Comparison of aortic root dimensions and geometries before and after transcatheter aortic valve implantation by 2- and 3-dimensional transesophageal echocardiography and multislice computed tomography
    Arnold C T Ng
    Department of Cardiology, The Department of Cardiothoracic Surgery, and the Department of Radiology, Leiden University Medical Center, Albinusdreef 2, Leiden, The Netherlands
    Circ Cardiovasc Imaging 3:94-102. 2010
    ..We assessed agreements between 2D and 3D TEE measurements with multislice computed tomography (MSCT) and changes in annular/LVOT areas and geometries after transcatheter aortic valve implantations (TAVI)...
  45. pmc Experience with transcatheter closure of secundum atrial septal defects using the Amplatzer septal occluder: a single centre study in 236 consecutive patients
    G Fischer
    Department of Paediatric Cardiology and Biomedical Engineering, Universitatsklinikum Kiel, Kiel, Germany
    Heart 89:199-204. 2003
    ..To evaluate the safety and efficacy of transcatheter closure of secundum atrial septal defects (ASD) with the Amplatzer septal occluder...
  46. ncbi Survival after transapical and transfemoral aortic valve implantation: talking about two different patient populations
    Sabine Bleiziffer
    Clinic for Cardiovascular Surgery, German Heart Center Munich, Lazarettstrasse 36, Munich, Germany
    J Thorac Cardiovasc Surg 138:1073-80. 2009
    ..We analyzed survival in patients undergoing transcatheter aortic valve implantation with special emphasis on the access site for implantation...
  47. ncbi Mental disorders and use of cardiovascular procedures after myocardial infarction
    B G Druss
    Department of Psychiatry, Yale University School of Medicine, VA Northeast Program Evaluation Center, New Haven, Conn, USA
    JAMA 283:506-11. 2000
    ..Similarly, mental disorders might be expected to be associated with lower rates of such procedures on the basis of clinical, socioeconomic, patient, and provider factors...
  48. ncbi Pulmonary arterial pressure during rest and exercise in healthy subjects: a systematic review
    G Kovacs
    Dept of Pulmonology, Medical University Graz, Graz, Austria
    Eur Respir J 34:888-94. 2009
    ....
  49. ncbi Role of multislice computed tomography in transcatheter aortic valve replacement
    David A Wood
    Division of Cardiology, St Paul s Hospital, University of British Columbia, Vancouver, British Columbia, Canada
    Am J Cardiol 103:1295-301. 2009
    ..Neither eccentricity nor calcific deposits appeared to contribute significantly to severity of paravalvular regurgitation after TAVR...
  50. ncbi Physiological assessment of coronary artery disease in the cardiac catheterization laboratory: a scientific statement from the American Heart Association Committee on Diagnostic and Interventional Cardiac Catheterization, Council on Clinical Cardiology
    Morton J Kern
    University of California, Irvine, USA
    Circulation 114:1321-41. 2006
    ..The goal of this statement is to provide a logical approach to the use of coronary physiological measurements in the catheterization lab to assist both clinicians and investigators in improving patient care...
  51. ncbi Aortic stenosis
    Blase A Carabello
    Baylor College of Medicine, Department of Medicine and Veterans Affairs Medical Center, Houston, TX, USA
    Lancet 373:956-66. 2009
    ..We discuss these issues in this Review...
  52. ncbi Role of echocardiography in percutaneous aortic valve implantation
    Robert R Moss
    Division of Cardiology, St Paul s Hospital, Vancouver, British Columbia, Canada
    JACC Cardiovasc Imaging 1:15-24. 2008
    ..This study was designed to investigate the usefulness and limitations of echocardiography in optimizing the outcome of percutaneous aortic valve implantation...
  53. ncbi Pulmonary arterial hypertension: noninvasive detection with phase-contrast MR imaging
    Javier Sanz
    Zena and Michael A Wiener Cardiovascular Institute, Marie Josee and Henry R Kravis Center for Cardiovascular Health, Mount Sinai School of Medicine, New York, NY 10029, USA
    Radiology 243:70-9. 2007
    ..To retrospectively identify pulmonary arterial (PA) flow parameters measured with phase-contrast magnetic resonance (MR) imaging that allow noninvasive diagnosis of chronic PA hypertension (PAH)...
  54. pmc Feasibility of real-time magnetic resonance imaging for catheter guidance in electrophysiology studies
    Saman Nazarian
    Department of Medicine, Division of Cardiology, Johns Hopkins Hospital, Carnegie 592C, 600 N Wolfe St, Baltimore, MD 21287, USA
    Circulation 118:223-9. 2008
    ..In this study, we sought to test the feasibility of performing electrophysiology studies with real-time MRI guidance...
  55. ncbi Percutaneous closure of the left atrial appendage versus warfarin therapy for prevention of stroke in patients with atrial fibrillation: a randomised non-inferiority trial
    David R Holmes
    Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Lancet 374:534-42. 2009
    ..We assessed the efficacy and safety of percutaneous closure of the LAA for prevention of stroke compared with warfarin treatment in patients with atrial fibrillation...
  56. ncbi Percutaneous left atrial appendage occlusion for patients in atrial fibrillation suboptimal for warfarin therapy: 5-year results of the PLAATO (Percutaneous Left Atrial Appendage Transcatheter Occlusion) Study
    Peter C Block
    Emory University, Atlanta, GA 30322, USA
    JACC Cardiovasc Interv 2:594-600. 2009
    ..The aim of this study was to determine 5-year clinical status for patients treated with percutaneous left atrial appendage transcatheter occlusion with the PLAATO (Percutaneous Left Atrial Appendage Transcatheter Occlusion) system...
  57. ncbi Borderline mean pulmonary artery pressure in patients with systemic sclerosis: transpulmonary gradient predicts risk of developing pulmonary hypertension
    Christopher J Valerio
    National Pulmonary Hypertension Unit, Royal Free Hospital, London, UK
    Arthritis Rheum 65:1074-84. 2013
    ....
  58. ncbi The use of intracardiac echocardiography and other intracardiac imaging tools to guide noncoronary cardiac interventions
    Susan S Kim
    Department of Internal Medicine, University of Chicago, Illinois, USA
    J Am Coll Cardiol 53:2117-28. 2009
    ..Most of this review will be devoted to intracardiac echocardiography, which currently has the broadest number of applications...
  59. ncbi Transapical transcatheter aortic valve implantation using the JenaValve™ system: acute and 30-day results of the multicentre CE-mark study
    Hendrik Treede
    Department of Cardiovascular Surgery, University Heart Center, Hamburg, Germany
    Eur J Cardiothorac Surg 41:e131-8. 2012
    ..The system consists of a tested porcine root valve mounted on a nitinol stent with feeler-guided positioning and clip fixation on the diseased leaflets...
  60. ncbi Cerebral emboli during left heart catheterization may cause acute brain injury
    Christian Lund
    Department of Neurology, Rikshospitalet University Hospital, 0027 Oslo, Norway
    Eur Heart J 26:1269-75. 2005
    Left heart catheterization carries a risk for cerebral complications...
  61. ncbi First-in-man implantation of a novel percutaneous valve: a new approach to medical device development
    Silvia Schievano
    Cardiovascular Unit, UCL Institute of Child Health, London, United Kingdom
    EuroIntervention 5:745-50. 2010
    ..To present our experience of 'first-in-man' implantation of a new percutaneous pulmonary valve into a dilated pulmonary trunk, using patient specific data to influence the design of the device and ensure patient safety...
  62. ncbi Distribution of calcium in the ascending aorta in patients undergoing transcatheter aortic valve implantation and its relevance to the transaortic approach
    Vinayak N Bapat
    Department of Cardiothoracic Surgery, St Thomas Hospital, London, United Kingdom
    JACC Cardiovasc Interv 5:470-6. 2012
    ..This study sought to identify how many patients suitable for transcatheter aortic valve implantation (TAVI) would have a contraindication for the transaortic (TAo) approach due to ascending aortic calcification...
  63. ncbi Percutaneous closure of patent foramen ovale in cryptogenic embolism
    Bernhard Meier
    Department of Cardiology, Bern University Hospital, Bern, Switzerland
    N Engl J Med 368:1083-91. 2013
    ..We investigated whether closure is superior to medical therapy...
  64. ncbi A challenging case of dislodged stent retrieval with the use of Goose neck snare kit
    Chao Yang Soon
    Division of Cardiology, Alexandra Hospital, Singapore, Singapore
    Catheter Cardiovasc Interv 75:630-3. 2010
    ..The patient recovered well and was discharged the following day...
  65. ncbi Transcatheter (TAVR) versus surgical (AVR) aortic valve replacement: occurrence, hazard, risk factors, and consequences of neurologic events in the PARTNER trial
    D Craig Miller
    Department of Cardiovascular and Thoracic Surgery, Falk Cardiovascular Research Center, Stanford University School of Medicine, 300 Pasteur Dr, Stanford, CA 94305, USA
    J Thorac Cardiovasc Surg 143:832-843.e13. 2012
    ..All neurologic events in the PARTNER randomized trial comparing transcatheter aortic valve replacement (TAVR) with surgical aortic valve replacement (AVR) were analyzed...
  66. ncbi Markov model for selection of aortic valve replacement versus transcatheter aortic valve implantation (without replacement) in high-risk patients
    Hemal Gada
    Department of Cardiovascular Medicine, Cleveland Clinic, Ohio, USA
    Am J Cardiol 109:1326-33. 2012
    ..In conclusion, TAVI satisfies current metrics of cost-effectiveness relative to AVR and might provide net health benefits at acceptable cost for selected high-risk patients among whom AVR is the current procedure of choice...
  67. ncbi Transcatheter aortic valve implantation: current and future approaches
    Josep Rodes-Cabau
    Quebec Heart and Lung Institute, Laval University, 2725 Chemin Ste Foy, G1V 4G5 Quebec City, QC, Canada
    Nat Rev Cardiol 9:15-29. 2012
    ....
  68. ncbi One-year results of transcatheter aortic valve implantation in severe symptomatic aortic valve stenosis
    Michael Gotzmann
    Department of Cardiology and Angiology, BG University Hospital Bergmannsheil, Bochum, Germany
    Am J Cardiol 107:1687-92. 2011
    ....
  69. ncbi Closure of patent foramen ovale versus medical therapy after cryptogenic stroke
    John D Carroll
    University of Colorado Denver University of Colorado Hospital, Aurora, CO 80045, USA
    N Engl J Med 368:1092-100. 2013
    ..We conducted a trial to evaluate whether closure is superior to medical therapy alone in preventing recurrent ischemic stroke or early death in patients 18 to 60 years of age...
  70. ncbi Trends, predictors, and outcomes of cerebrovascular events related to percutaneous coronary intervention: a 16-year single-center experience
    Scott J Hoffman
    Division of Cardiovascular Diseases, Mayo Clinic, Rochester, Minnesota 55905, USA
    JACC Cardiovasc Interv 4:415-22. 2011
    ..We sought to determine trends, predictors, in-hospital and long-term outcomes of cerebrovascular events (CVE) related to percutaneous coronary intervention (PCI) over a 16-year period...
  71. ncbi Incidence and treatment of procedural cardiovascular complications associated with trans-arterial and trans-apical interventional aortic valve implantation in 412 consecutive patients
    Rüdiger Lange
    German Heart Center Munich, Munich, Germany
    Eur J Cardiothorac Surg 40:1105-13. 2011
    ..Herein, we report a complete, prospective analysis of complications occurring during transvascular and trans-apical implantations with two different prostheses...
  72. ncbi Crimping may affect the durability of transcatheter valves: an experimental analysis
    Philipp Kiefer
    Department of Cardiac Surgery, Heart Center, Institute of Pathology, Faculty of Veterinary Medicine, University of Leipzig, Leipzig, Germany
    Ann Thorac Surg 92:155-60. 2011
    ..Transcatheter aortic valve implantation has gained widespread acceptance to treat elderly high-risk patients with aortic stenosis. We used a subcutaneous rat model to evaluate whether crimping may affect valve long-term durability...
  73. ncbi Diffusion-weighted MRI determined cerebral embolic infarction following transcatheter aortic valve implantation: assessment of predictive risk factors and the relationship to subsequent health status
    Timothy A Fairbairn
    Division of Cardiovascular and Neuronal Remodelling, Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, UK
    Heart 98:18-23. 2012
    ..Silent' cerebral infarction and stroke are complications of transcatheter aortic valve implantation (TAVI)...
  74. ncbi Reduced number and function of endothelial progenitor cells in patients with aortic valve stenosis: a novel concept for valvular endothelial cell repair
    Yasuharu Matsumoto
    Department of Cardiology, Heart Center Leipzig, University of Leipzig, Strumpellstrasse 39, D 04289 Leipzig, Germany
    Eur Heart J 30:346-55. 2009
    ..This study investigated whether degenerative AV stenosis (AS) is associated with the presence of valvular endothelial senescence and a reduction in the number and function of endothelial progenitor cells (EPCs)...
  75. ncbi Racial differences in the use of invasive cardiovascular procedures: review of the literature and prescription for future research
    N R Kressin
    Center for Health Quality, Outcomes and Economic Research, Veterans Affairs Medical Center, 200 Springs Road, Building 70 (152, Bedford, MA 01730, USA
    Ann Intern Med 135:352-66. 2001
    ..Future studies should comprehensively and simultaneously examine the full range of patient, physician, and health care system variables related to racial differences in the provision of invasive cardiac procedures...
  76. ncbi Transapical aortic valve implantation: step by step
    Thomas Walther
    Universitat Leipzig, Herzzentrum, Klinik fur Herzchirurgie, Leipzig, Germany
    Ann Thorac Surg 87:276-83. 2009
    ..Transapical aortic valve implantation is a new minimally invasive technique for beating heart, off-pump, aortic valve implantation in high-risk patients...
  77. ncbi Adverse event rates in congenital cardiac catheterization: a new understanding of risks
    Lisa Bergersen
    Children s Hospital Boston, Harvard Medical School Department of Cardiology, Boston, MA 02115, USA
    Congenit Heart Dis 3:90-105. 2008
    ....
  78. ncbi Acute left ventricle diastolic function improvement after transcatheter aortic valve implantation
    Alexandra Gonçalves
    Cardiovascular Institute, Unit of Methodology of the Investigation and Clinical Epidemiology, Preventive Medicine Department, Hospital Clinico San Carlos, Plaza de Cristo Rey, Madrid 28040, Spain
    Eur J Echocardiogr 12:790-7. 2011
    ..This study aimed to determine the acute haemodynamic effects of transcatheter aortic valve implantation (TAVI) in left ventricle (LV) diastolic performance, immediately after aortic valvuloplasty and prosthesis deployment...
  79. ncbi Transfemoral aortic valve implantation new criteria to predict vascular complications
    Kentaro Hayashida
    Institut Cardiovasculaire Paris Sud, Massy, France
    JACC Cardiovasc Interv 4:851-8. 2011
    ..This study sought to evaluate the incidence, impact, and predictors of vascular complications in transcatheter aortic valve implantation (TAVI)...
  80. ncbi Quality of life among patients undergoing transcatheter aortic valve implantation
    Markus Krane
    Department of Cardiovascular Surgery, German Heart Center Munich, Technische Universitat Munchen, Munich, Germany
    Am Heart J 160:451-7. 2010
    ..Especially in this subset of patients, the expected improvement of quality of life (QoL) after valve implantation will be critical for decision-making for TAVI...
  81. ncbi Transaortic Transcatheter Aortic valve implantation using Edwards Sapien valve: a novel approach
    Vinayak Bapat
    Department of Cardiothoracic Surgery, Guy s and St Thomas Hospital, London, United Kingdom
    Catheter Cardiovasc Interv 79:733-40. 2012
    ..To evaluate feasibility and outcome of Transoartic Transcatheter Sapien valve implantation...
  82. ncbi Transcatheter aortic valve implantation through the ascending aorta: an alternative option for no-access patients
    Robert Bauernschmitt
    Clinic of Cardiovascular Surgery, The Technical University, Munich, Germany
    Heart Surg Forum 12:E63-4. 2009
    ..The ascending aorta approach might help to expand the implantation possibilities for those patients for whom the typical access sites are not available...
  83. ncbi Early and persistent intraventricular conduction abnormalities and requirements for pacemaking after percutaneous replacement of the aortic valve
    Nicolo Piazza
    Department of Cardiology, Thoraxcenter, Erasmus Medical Center, Rotterdam, The Netherlands
    JACC Cardiovasc Interv 1:310-6. 2008
    ..In this retrospective study, we examined the incidence of post-procedural conduction abnormalities and the need for pacing in patients undergoing percutaneous implantation of the aortic valve...
  84. ncbi Transcatheter aortic valve implantation: evidence on safety and efficacy compared with medical therapy. A systematic review of current literature
    L Figulla
    Department of Cardiology, University Hospital of Essen, Hufelandstrasse 55, Essen, Germany
    Clin Res Cardiol 100:265-76. 2011
    ..In this work, the methodology was applied to provide objective evidence on the efficacy and safety of TAVI at 1-year follow-up and to assess whether TAVI confers a survival benefit compared with medical therapy...
  85. ncbi The tricuspid valve: current perspective and evolving management of tricuspid regurgitation
    Jason H Rogers
    Division of Cardiovascular Medicine, University of Davis Medical Center, 4860 Y St, Suite 2820, Sacramento, CA 95817, USA
    Circulation 119:2718-25. 2009
    ..In this article, we review the anatomy, pathophysiology, and value of mechanical correction of TR, including potential transcatheter therapies for TR...
  86. ncbi Technique of transcatheter aortic valve implantation with the Edwards-Sapien heart valve using the transfemoral approach
    Alain Cribier
    Department of Cardiology, Rouen University, Hospital Charles, Nicolle and INSERM 144, Rouen, France
    Herz 34:347-56. 2009
    ..At the present time, the indications should be restricted to nonoperable or surgical high-risk patients and the procedure performed by experienced and formally trained physicians working in an optimal multidisciplinary environment...
  87. ncbi Transcatheter valve implantation for patients with aortic stenosis: a position statement from the European Association of Cardio-Thoracic Surgery (EACTS) and the European Society of Cardiology (ESC), in collaboration with the European Association of Percu
    Alec Vahanian
    Hopital Bichat, Paris, France
    Eur J Cardiothorac Surg 34:1-8. 2008
    ..To critically review the available transcatheter aortic valve implantation techniques and their results, as well as propose recommendations for their use and development...
  88. ncbi Postoperative permanent pacemaker implantation in patients undergoing trans-catheter aortic valve implantation: what is the incidence and are there any predicting factors?
    Matthew G D Bates
    Institute for Ageing and Health, Newcastle University, and Department of Cardiology, Freeman Hospital, Newcastle upon Tyne NE2 4HH, UK
    Interact Cardiovasc Thorac Surg 12:243-53. 2011
    ..All patients should be made aware of the high risk of PPM implantation with TAVI...
  89. ncbi The acute hemodynamic effects of MitraClip therapy
    Robert J Siegel
    Cedars Sinai Medical Center, 8700 Beverly Boulevard, Los Angeles, CA 90048 1804, USA
    J Am Coll Cardiol 57:1658-65. 2011
    ..The objective of this study was to evaluate the acute hemodynamic consequences of mitral valve (MV) repair with the MitraClip device (Abbott Vascular, Menlo Park, California)...
  90. ncbi REVEAL Registry: correlation of right heart catheterization and echocardiography in patients with pulmonary arterial hypertension
    Harrison W Farber
    Boston University School of Medicine, 715 Albany Street, Boston, MA 02118, USA
    Congest Heart Fail 17:56-64. 2011
    Cardiopulmonary hemodynamics are estimated by Doppler echocardiogram (ECHO) and measured by right heart catheterization (RHC) in patients with pulmonary arterial hypertension (PAH)...
  91. ncbi Current concepts of integrated coronary physiology in the catheterization laboratory
    Morton J Kern
    Division of Cardiology, University of California, Irvine, California 92868 4080, USA
    J Am Coll Cardiol 55:173-85. 2010
    ..This review addresses selected pertinent concepts and studies supporting the integration of coronary physiology in the catheterization laboratory for optimal patient outcomes...
  92. ncbi Persistent conduction abnormalities and requirements for pacemaking six months after transcatheter aortic valve implantation
    Nicolo Piazza
    Erasmus Medical Center, Thoraxcenter, Rotterdam, The Netherlands
    EuroIntervention 6:475-84. 2010
    ..In this prospective study, we examined the incidence of post-procedural and 6-month conduction abnormalities and need for permanent pacemaking after TAVI...
  93. ncbi Utility of right ventricular free wall speckle-tracking strain for evaluation of right ventricular performance in patients with pulmonary hypertension
    Yuko Fukuda
    Division of Cardiovascular Medicine, Department of Internal Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    J Am Soc Echocardiogr 24:1101-8. 2011
    ....
  94. ncbi Renal function as predictor of mortality in patients after percutaneous transcatheter aortic valve implantation
    Jan Malte Sinning
    Medizinische Klinik und Poliklinik II, Universitatsklinikum Bonn, Rheinische Friedrich Wilhelms Universitat, Bonn, Germany
    JACC Cardiovasc Interv 3:1141-9. 2010
    ..The aim of this study was to determine the influence of baseline renal function and periprocedural acute kidney injury (AKI) on prognosis after transcatheter aortic valve implantation (TAVI)...
  95. ncbi Incidence and predictors of atrioventricular conduction impairment after transcatheter aortic valve implantation
    Laurent Roten
    Department of Cardiology, Inselspital, Bern University Hospital, and University of Bern, Bern, Switzerland
    Am J Cardiol 106:1473-80. 2010
    ....
  96. pmc Transapical aortic valve replacement under real-time magnetic resonance imaging guidance: experimental results with balloon-expandable and self-expanding stents
    Keith A Horvath
    Cardiothoracic Surgery Research Program, National Heart, Lung and Blood Institute, National Institutes of Health, Bethesda, MD, USA
    Eur J Cardiothorac Surg 39:822-8. 2011
    ..Whether there are different advantages to SE or BE stents is unknown. We report rtMRI-guided tAVI in a porcine model using both SE and BE stents, and compare the differences between the stents...
  97. ncbi Results of transcatheter closure of perimembranous ventricular septal defect
    Jian Zuo
    Department of Cardiovascular Surgery, Xijing Hospital, The Fourth Military Medical University, Xi an, Shaanxi, China
    Am J Cardiol 106:1034-7. 2010
    ..The major concern is the occurrence of cAVB. Long-term investigation is needed to assess the efficacy and safety compared to surgery...
  98. ncbi Frequency of conduction abnormalities after transcatheter aortic valve implantation with the Medtronic-CoreValve and the effect on left ventricular ejection fraction
    Apostolos Tzikas
    Department of Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    Am J Cardiol 107:285-9. 2011
    ..In conclusion, the induction of new conduction abnormalities after TAVI with the Medtronic-CoreValve was associated with a lack of improvement in LV systolic function...
  99. ncbi Comparison of bare metal stenting and percutaneous pulmonary valve implantation for treatment of right ventricular outflow tract obstruction: use of an x-ray/magnetic resonance hybrid laboratory for acute physiological assessment
    Philipp Lurz
    UCL Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, Cardiorespiratory Unit, London, UK
    Circulation 119:2995-3001. 2009
    ..In this study, we assessed the acute physiological effects of BMS versus percutaneous pulmonary valve implantation (PPVI) using an x-ray/magnetic resonance hybrid laboratory...
  100. ncbi Unexpected complications of transapical aortic valve implantation
    Nawwar Al-Attar
    Department of Cardiovascular Surgery, Bichat Claude Bernard Hospital, Paris, France
    Ann Thorac Surg 88:90-4. 2009
    ..However, specific problems of this new procedure are not well-described. Unexpected complications due to the procedure and their management are reported...
  101. ncbi Results of transfemoral or transapical aortic valve implantation following a uniform assessment in high-risk patients with aortic stenosis
    Dominique Himbert
    Department of Cardiology, Assistance Publique Hopitaux de Paris, Bichat Claude Bernard Hospital, Paris, France
    J Am Coll Cardiol 54:303-11. 2009
    ..We sought to describe the results of a strategy offering either transfemoral or transapical aortic valve implantation in high-risk patients with severe aortic stenosis...

Research Grants62

  1. Fractional flow reserve measurement based on coronary angiographic images
    SABEE Y MOLLOI; Fiscal Year: 2010
    ..This quantification technique could be used to measure fractional flow reserve in patients undergoing standard coronary arteriography. ..
  2. Exercise training and blood pressure in hypertension: integrated mechanisms
    Noreen F Rossi; Fiscal Year: 2012
    ....
  3. Novel Regenerative Therapy for Myocardial Infarction
    Andrew R Mendelsohn; Fiscal Year: 2011
    ..PUBLIC HEALTH RELEVANCE: We are developing a new regenerative therapy for the treatment of myocardial infarction (heart attacks). A new drug will stimulate the heart to repair itself. ..
  4. Vascular and Skeletal Muscle Function in Gulf War Veterans Illness
    Scott Kinlay; Fiscal Year: 2013
    ..This Pilot study may also provide insights into other chronic illness characterized by fatigue and other musculoskeletal symptoms, such as peripheral vascular disease and congestive heart failure. ..
  5. Right Heart-Pulmonary Vascular Interactions in Bronchopulmonary Dysplasia
    Marlowe Eldridge; Fiscal Year: 2013
    ..To answer our questions, we propose to use a combination of state-of-the-art MR imaging, right heart catheterization, 3D echocardiography and exercise to reveal any abnormalities in the pulmonary vasculature, right heart, ..
  6. The Role of Vascular Innervation on Tissue-type Plasminogen Activator Release
    JAMES ANTHONY SHEERIN MULDOWNEY; Fiscal Year: 2013
    ..With the overwhelming prevalence of vascular disease nationally, and worldwide, new insights and strategies have the potential translate to a tremendous public health impact...
  7. Protein biomarkers of pulmonary hypertension in sickle cell disease
    Mark E McComb; Fiscal Year: 2013
    ..Current diagnosis is by right heart catheterization (RHC) as echocardiography is frequently inaccurate and may be falsely positive...
  8. The ISCHEMIA-CKD Trial-CCC-Lead Application
    Sripal Bangalore; Fiscal Year: 2013
    ..The importance of this question to be addressed by ISCHEMIA-CKD is the reason it was ranked by the Institute of Medicine among the top 100 US priorities for comparative effectiveness research. ..
  9. Novel Biomarkers Predictive of Heparin-Induced Thrombocytopenia
    Barbara A Konkle; Fiscal Year: 2010
    ..This study will help identify patients most at risk of developing HIT with heparin therapy so that the approach to their care can be altered, and thus, improved. ..
  10. Reliable Evaluation of Coronary Artery Disease using Myocardial BOLD MRI with CO2
    Rohan Dharmakumar; Fiscal Year: 2013
    ..These studies are expected to provide the fundamental scientific basis for a non-invasive and reliable imaging strategy for evaluating prognosis of patients with coronary artery disease. ..
  11. National Surveillance of Acute Kidney Injury Following Cardiac Catheterization
    Michael E Matheny; Fiscal Year: 2013
    ..Finally, the informatics infrastructure and NLP development has the potential to be applied in a wide variety of exposures and outcomes beyond AKI for cardiac catheterization surveillance. ..
  12. ISCHEMIA-CKD SDCC
    SEAN M O'BRIEN; Fiscal Year: 2013
    ..The importance of this question to be addressed by ISCHEMIA-CKD is the reason it was ranked by the Institute of Medicine among the top 100 US priorities for comparative effectiveness research. ..
  13. The Impact of Public Reporting on Outcomes and Case Selection for PCI
    KAREN ELLEN JOYNT; Fiscal Year: 2013
    ....
  14. Chicago Healthy Aging Low Risk MRI Angiography (CHARISMA) Study
    Donald M Lloyd-Jones; Fiscal Year: 2012
    ..for imaging of coronary arteries using magnetic resonance imaging (MRI) without having to perform invasive heart catheterization. The overall goal of this application is to better define the mechanisms underlying the long-term ..
  15. Mechanisms of Right Ventricular Dysfunction in PAH
    DAVID ALAN KASS; Fiscal Year: 2013
    ..in both IPAH and SSc-PAH;2) determine RV function and PA interaction by invasive pressure-volume and right heart catheterization, using rate pacing and leg-exercise to assess reserve RV function;and 3) obtain RV biopsies to test the ..
  16. The Ischemia Trial - CCC
    Judith S Hochman; Fiscal Year: 2013
    ..Patients will be randomized to an invasive group that will undergo routine cath with optimal revascularization, if feasible, plus OMT or to a group that receives OMT alone. ..
  17. The Survival from Acute Myocardial Infarction (SAMI) Initiative
    Henry H Ting; Fiscal Year: 2013
    ..The ARG registry will be used as the data collection tool to identify areas for improvement pre-intervention and to define the impact post-intervention. ..
  18. Prostacyclin-secreting Cells as Therapy for Pulmonary Artery Hypertension
    Ke He Ruan; Fiscal Year: 2010
    ..in vivo distribution of fluorescently labeled transfected cells and monitor pulmonary pressures (via right heart catheterization) as an indicator of efficacy in treating PAH...
  19. The ISCHEMIA Trial - IICC
    Leslee J Shaw; Fiscal Year: 2012
    ..Patients will be randomized to an invasive group that will undergo routine cath with optimal revascularization, if feasible, plus OMT or to a group that receives OMT alone. ..
  20. Cincinnati Center of Excellence in Hemoglobinopathies Research
    Punam Malik; Fiscal Year: 2013
    ..End of Abstract) ..
  21. Novel Micro-Implant to Measure Intracardiac Pressure in Congenital Heart Patients
    Nader Najafi; Fiscal Year: 2013
    ..Finally, this study will support investigators during the application process to obtain Investigational Device Exemption from the FDA for the initial feasibility studies in infants with these complex forms of congenital heart disease. ..
  22. The ISCHEMIA Trial - EQOL
    Daniel B Mark; Fiscal Year: 2013
    ..Patients randomized to the invasive group will undergo optimal revascularization following study guidelines. ..
  23. Discovery &Application of Proteomics-Based Biomarkers of Early Myocardial Injury
    Marc S Sabatine; Fiscal Year: 2012
    ..This project describes the application of new proteomics technology for biomarker discovery and validation of early markers of myocardial injury. ..
  24. Balancing the Risks of Ischemia and Bleeding in Percutaneous Coronary Interventio
    Robert Yeh; Fiscal Year: 2013
    ..The research will demonstrate how the end products of outcomes research can be translated into innovative interventions that can "personalize" medical decisions and ultimately improve patient care. ..
  25. Cardiac Structure and Function in Early Familial Cardiomyopathy
    Janaka Wansapura; Fiscal Year: 2013
    ..Furthermore, with training and research experience provided by this award the candidate will be able to design more effective experiments aimed at improving non-invasive imaging methods for evaluation of disease models. ..
  26. Metabolomic Biomarkers of Early Myocardial Injury
    Marc S Sabatine; Fiscal Year: 2013
    ....
  27. Identifying and Facilitating Ventricular Recovery on Mechanical Support
    John Gorcsan; Fiscal Year: 2011
    ..The predictive power of routine clinical peak exercise oxygen consumption and right heart catheterization will be compared to refine selection criteria for LVAD removal...
  28. Role of Endothelial Progenitor Cells in vascular Aging and Calcification
    Amir Lerman; Fiscal Year: 2013
    ....
  29. Differences in Quality, Cost, and Access between VA and Fee Basis CABG and PCI
    THOMAS MCMILLIN MADDOX; Fiscal Year: 2013
    ....
  30. CARDIAC PERFORMANCE BY QUANTITATIVE ECHOCARDIOGRAPHY
    John Gorcsan; Fiscal Year: 2010
    ..power, in comparison to a routine clinical assessment that includes exercise oxygen consumption and right heart catheterization. We will also correlate LV recovery with markers of myocardial inflammation and TNF-alpha expression to ..
  31. PATIENT MOTION DETECTION AND COMPENSATION IN SPECT
    Michael A King; Fiscal Year: 2013
    ..The proposed research will also provide a better understanding of patient motion during medical imaging and treatment. ..
  32. Genetic Mediators of Metabolic Cardiovascular Disease Risk
    William E Kraus; Fiscal Year: 2010
    ..We will combine knowledge of peripheral small molecular metabolic markers of cardiovascular risk, peripheral gene expression profiles and a genome wide SNP screen to develop comprehensive molecular profiles of cardiovascular risk. ..
  33. Oxidation in Inflammation and Cardiovascular Disease
    Stanley L Hazen; Fiscal Year: 2013
    ..It may also lead to important insights for atherosclerosis risk assessment, diagnosis and therapy. ..
  34. Intracranial Atherosclerosis and predictors of Post-CABG Depression
    Hochang B Lee; Fiscal Year: 2013
    ....
  35. The clinical impact of pulmonary vascular remodeling in smokers
    George R Washko; Fiscal Year: 2013
    ..are existing tools that may be used to investigate the aggregate effect of these processes such as right heart catheterization, echocardiography, and measurements of diffusing capacity for carbon monoxide (DLCO), none can ..
  36. Individualized Risk Stratification Using the Genomic Contribution
    David M Seo; Fiscal Year: 2013
    ..We will use the genetic risk factors in conjunction with traditional cardiovascular risk factors to improve artery disease risk classification in a clinical setting. ..
  37. Temporal Trends in Dialysis-requiring Acute Kidney Injury in the United States
    Raymond Hsu; Fiscal Year: 2012
    ....
  38. Using simulation for teaching femoral arterial access: A multi centric collaborat
    Hitinder S Gurm; Fiscal Year: 2013
    ..Impact: The introduction of simulation system to teach femoral arterial access across a number of hospitals connected in a learning network will ensure rapid dissemination and early reduction in procedural complications. ..
  39. Network for Cardiothoracic Surgical Investigations in Cardiovascular Medicine
    Irving L Kron; Fiscal Year: 2013
    ..abstract_text> ..
  40. Race and cardiac catheterization use in the setting of acute myocardial infarctio
    Saif Rathore; Fiscal Year: 2009
    ..of black patients, or a combination of processes;and the impact of racial differences in cardiac catheterization use on long-term survival - will help inform current efforts to address racial disparities in health and health care use ..
  41. IDIOPATHIC DILATED CARDIOMYOPATHY
    Virginia Michels; Fiscal Year: 1991
    ..Identification of the sources of variability of ANP levels and echocardiographic variables of cardiac structure and function will be relevant for cardiac diseases other than IDC...
  42. QUANTITATIVE VENTRICULOGRAPHY USING DUAL-ENERGY DSA
    MICHAEL VAN LYSEL; Fiscal Year: 1992
    ..Furthermore, these techniques have the potential to provide a high resolution outpatient test for coronary artery disease and for the serial assessment of rest and exercise ventricular function in patients with cardiac disease...
  43. 3D CORONARY RECONSTRUCTION AND MULTIMODALITY FUSION
    Shiuh Yung Chen; Fiscal Year: 2003
    ..abstract_text> ..
  44. ER beta selective agonist coronary protection-menopause
    R Hermsmeyer; Fiscal Year: 2005
    ..The new ERbetaA is to be contrasted with PremPro(r) (oral conjugated equine estrogens plus medroxyprogesterone acetate) which failed to provide cardiovascular protection in the Women's Health Initiative. ..
  45. TECHNIQUES FOR DETECTION OF LESIONS IN CORONARY ARTERIES
    HOWARD KANTOR; Fiscal Year: 1991
    ..Changes in flow in this system will be monitored with the radioactive microsphere blood flow method...
  46. FACTORS THAT REGULATE COLLATERAL PERFUSION
    David Harrison; Fiscal Year: 1993
    ..Because of our past experience in this field and a variety of unique experimental preparations and technology available in our laboratories, we are in a unique position to accomplish these goals...
  47. DETERMINANTS OF VASODILATOR RESPONSE IN HEART FAILURE
    Milton Packer; Fiscal Year: 1992
    ..In a series of hemodynamic investigations in patients with heart failure undergoing right heart catheterization, tolerance will be induced to intravenous nitroglycerin to determine if its occurrence is the result of ..
  48. The Role of Endothelias Dysfunction in HIV-Associated Pulmonary Hypertension
    Jennifer Ho; Fiscal Year: 2009
    ..to an acute vasodilator challenge with inhaled iloprost in HIV-infected patients with PAH during right heart catheterization. The study design will involve a cross-sectional study of HIV-infected patients already enrolled in Dr...
  49. A Novel Approach to the Treatment of Cardiac Arrhythmia: A Robotic Catheter for E
    Shaphan Jernigan; Fiscal Year: 2009
    ..Benefiting from the precision and repeatability of computer-based control, these catheters have the potential to impact a variety of medical fields, including cardiology, cardiac surgery, pediatric surgery and urology. ..
  50. CLONING OF FAMILIAL PRIMARY PULMONARY HYPERTENSION GENE
    William Nichols; Fiscal Year: 2006
    ..abstract_text> ..
  51. KUMAKHOV OPTICS FOR CLINICAL DUAL-ENERGY ANGIOGRAPHY
    QI FAN XIAO; Fiscal Year: 1993
    ..The researcher and collaborators involved are those most responsible for inventing and developing the Kumakhov lens and SRL source technology...
  52. Natriuretic Peptides, Genes, and Diastolic Heart Failure
    Thomas Wang; Fiscal Year: 2007
    ..Each of these skills will be critical to the candidate's long-term goal of becoming an independent clinical investigator with a focus on heart failure. ..
  53. MOTION CORRECTED TREADMILL NUCLEAR ANGIOGRAPHY
    Jeffrey Lacy; Fiscal Year: 2001
    ..abstract_text> ..
  54. Novel MPO-derived plasma lipids as predictors of major adverse coronary events
    David Ford; Fiscal Year: 2009
    ..Identifying these novel lipid oxidation products as predictors of future major adverse coronary events has the potential to significantly impact care and outcomes of patients with coronary artery disease. ..
  55. Coronary Disease Detection by Thalluim SPECT and Fast CT
    Lewis Becker; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  56. MAGNETIC RESONANCE CORONARY ANGIOGRAPHY
    John Oshinski; Fiscal Year: 2001
    ....
  57. ANXIETY & VAGAL CONTROL OF THE HEART IN CORONARY DISEASE
    Lana Watkins; Fiscal Year: 2002
    ..abstract_text> ..
  58. Blood Pressure and Risks of Cardiac Catheterization
    Cheryl Dumont; Fiscal Year: 2005
    ..Decisions regarding TIB and control of blood pressure during sheath removal are made by nurses. Knowledge guiding nursing protocols for care post CC and PCI has not been evidence based. ..
  59. PORTABLE EXTRACORPOREAL RESUSCITATION CONSOLE
    Scott Merz; Fiscal Year: 1999
    ..Another likely market is ECLS in intensive care units. ..
  60. IMPLANTABLE MYOCARDIAL ISCHEMIA DETECTION TECHNOLOGY
    ANANTH NATARAJAN; Fiscal Year: 1999
    ..IMIDT will very likely be licenced to an established pacemaker/defibrillator company that will 'piggyback' it onto such devices. ..
  61. IMPROVING ADHERENCE TO PHARMACOLOGICAL TREATMENT
    Ira Ockene; Fiscal Year: 2003
    ..Proportion of selected non-lipid-lowering prescribed medication taken by patients as measured by CMA; and 3. Percentage of patients with an LDL level <130 mg per dl ..