central venous catheterization

Summary

Summary: Placement of an intravenous catheter in the subclavian, jugular, or other central vein for central venous pressure determination, chemotherapy, hemodialysis, or hyperalimentation.

Top Publications

  1. ncbi Central venous catheterization
    James D Newton
    N Engl J Med 357:943; author reply 944-5. 2007
  2. ncbi Prevention of intravascular catheter-related infections
    L A Mermel
    Division of Infectious Diseases, Rhode Island Hospital and Brown University School of Medicine, Providence 02903, USA
    Ann Intern Med 132:391-402. 2000
  3. ncbi Complications of femoral and subclavian venous catheterization in critically ill patients: a randomized controlled trial
    J Merrer
    Service de Reanimation Medicale, Hôpital de Poissy St Germain en Laye, 10 rue du Champ Gaillard, 78303 Poissy, France
    JAMA 286:700-7. 2001
  4. ncbi Incidence of thrombotic complications in patients with haematological malignancies with central venous catheters: a prospective multicentre study
    Agostino Cortelezzi
    Department of Haematology and Bone Marrow Transplantation Unit, IRCCS Fondazione Ospedale Maggiore Policlinico and University of Milan, Milan, Italy
    Br J Haematol 129:811-7. 2005
  5. ncbi A comparison of two antimicrobial-impregnated central venous catheters. Catheter Study Group
    R O Darouiche
    Department of Medicine, Baylor College of Medicine and Veterans Affairs Medical Center, Houston, TX 77030, USA
    N Engl J Med 340:1-8. 1999
  6. ncbi An unseen danger: frequency of posterior vessel wall penetration by needles during attempts to place internal jugular vein central catheters using ultrasound guidance
    Michael Blaivas
    Northside Hospital Forsyth, Cummings, GA, USA
    Crit Care Med 37:2345-9; quiz 2359. 2009
  7. ncbi Effect of an education program on decreasing catheter-related bloodstream infections in the surgical intensive care unit
    Craig M Coopersmith
    Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Crit Care Med 30:59-64. 2002
  8. ncbi Central venous and mixed venous oxygen saturation in critically ill patients
    C Ladakis
    Athens University School of Nursing Intensive Care Unit at Agioi Anargyroi Cancer Hospital of Kifissia, Athens, Greece
    Respiration 68:279-85. 2001
  9. ncbi Current practice of internal jugular venous cannulation in a university anesthesia department: influence of operator experience on success of cannulation and arterial injury
    John G Augoustides
    Department of Anesthesia, Cardiothoracic Section, Hospital of the University of Pennsylvania, Philadelphia, PA 19104 4283, USA
    J Cardiothorac Vasc Anesth 16:567-71. 2002
  10. ncbi Thromboembolic complications of cancer: epidemiology, pathogenesis, diagnosis, and treatment
    Douglas E Sutherland
    Division of Hematology, Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Am J Hematol 72:43-52. 2003

Detail Information

Publications248 found, 100 shown here

  1. ncbi Central venous catheterization
    James D Newton
    N Engl J Med 357:943; author reply 944-5. 2007
  2. ncbi Prevention of intravascular catheter-related infections
    L A Mermel
    Division of Infectious Diseases, Rhode Island Hospital and Brown University School of Medicine, Providence 02903, USA
    Ann Intern Med 132:391-402. 2000
    ..To review the literature on prevention of intravascular catheter-related infections...
  3. ncbi Complications of femoral and subclavian venous catheterization in critically ill patients: a randomized controlled trial
    J Merrer
    Service de Reanimation Medicale, Hôpital de Poissy St Germain en Laye, 10 rue du Champ Gaillard, 78303 Poissy, France
    JAMA 286:700-7. 2001
    ..Whether venous catheterization at the femoral site is associated with an increased risk of complications compared with that at the subclavian site is debated...
  4. ncbi Incidence of thrombotic complications in patients with haematological malignancies with central venous catheters: a prospective multicentre study
    Agostino Cortelezzi
    Department of Haematology and Bone Marrow Transplantation Unit, IRCCS Fondazione Ospedale Maggiore Policlinico and University of Milan, Milan, Italy
    Br J Haematol 129:811-7. 2005
    ..This study shows that the impact on clinical practice of symptomatic CVC-related thrombotic complications is not negligible in patients with haematological malignancies...
  5. ncbi A comparison of two antimicrobial-impregnated central venous catheters. Catheter Study Group
    R O Darouiche
    Department of Medicine, Baylor College of Medicine and Veterans Affairs Medical Center, Houston, TX 77030, USA
    N Engl J Med 340:1-8. 1999
    ..We compared the rates of catheter colonization and catheter-related bloodstream infection associated with these two kinds of antiinfective catheters...
  6. ncbi An unseen danger: frequency of posterior vessel wall penetration by needles during attempts to place internal jugular vein central catheters using ultrasound guidance
    Michael Blaivas
    Northside Hospital Forsyth, Cummings, GA, USA
    Crit Care Med 37:2345-9; quiz 2359. 2009
    ..To evaluate the frequency of unsuspected posterior vessel wall penetration of the internal jugular vein during ultrasound-guided needle cannulation...
  7. ncbi Effect of an education program on decreasing catheter-related bloodstream infections in the surgical intensive care unit
    Craig M Coopersmith
    Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    Crit Care Med 30:59-64. 2002
    ..The purpose of the study was to determine whether an education initiative aimed at improving central venous catheter insertion and care could decrease the rate of primary bloodstream infections...
  8. ncbi Central venous and mixed venous oxygen saturation in critically ill patients
    C Ladakis
    Athens University School of Nursing Intensive Care Unit at Agioi Anargyroi Cancer Hospital of Kifissia, Athens, Greece
    Respiration 68:279-85. 2001
    ..SvO2 can be estimated with great accuracy by ScvO2 in 92% of the patients using a power model...
  9. ncbi Current practice of internal jugular venous cannulation in a university anesthesia department: influence of operator experience on success of cannulation and arterial injury
    John G Augoustides
    Department of Anesthesia, Cardiothoracic Section, Hospital of the University of Pennsylvania, Philadelphia, PA 19104 4283, USA
    J Cardiothorac Vasc Anesth 16:567-71. 2002
    ..To describe current cannulation of the internal jugular vein (CIJV) practice in a university anesthesia department...
  10. ncbi Thromboembolic complications of cancer: epidemiology, pathogenesis, diagnosis, and treatment
    Douglas E Sutherland
    Division of Hematology, Department of Medicine, University of Southern California Keck School of Medicine, Los Angeles, California 90033, USA
    Am J Hematol 72:43-52. 2003
    ..The purpose of this review is to examine our current understanding of thrombosis as a complication of cancer and cancer therapy. The review includes a discussion of the epidemiology, pathophysiology, diagnosis and treatment...
  11. ncbi Central venous line-related thrombosis in children: association with central venous line location and insertion technique
    Christoph Male
    Children s Hospital, University of Vienna, Austria
    Blood 101:4273-8. 2003
    ..If subclavian vein placement is necessary, CVL insertion by venous cut-down appears preferable over percutaneous insertion...
  12. ncbi Prevalence of the use of central venous access devices within and outside of the intensive care unit: results of a survey among hospitals in the prevention epicenter program of the Centers for Disease Control and Prevention
    Michael Climo
    Hunter Holmes McGuire Veteran Affairs Medical Center, Richmond, Virginia 23249, USA
    Infect Control Hosp Epidemiol 24:942-5. 2003
    ..To determine the prevalence of central venous catheter (CVC) use among patients both within and outside the ICU setting...
  13. ncbi Central venous access ports placed by interventional radiologists: experience with 125 consecutive patients
    H Lorch
    Department of Radiology, Medical University of Lubeck, Ratzeburger Allee 160, D 23538 Lubeck, Germany
    Cardiovasc Intervent Radiol 24:180-4. 2001
    ..To assess safety and function of central venous port systems implanted percutaneously in the interventional radiology suite...
  14. ncbi Treatment of hemodialysis-related central venous stenosis or occlusion: results of primary Wallstent placement and follow-up in 50 patients
    P Haage
    Department of Diagnostic Radiology, University of Technology, Aachen, Germany
    Radiology 212:175-80. 1999
    ..To analyze the effectiveness of stent placement as the primary treatment for central venous obstruction in patients undergoing hemodialysis...
  15. ncbi Guidelines for the prevention of intravascular catheter-related infections
    NAOMI P O'GRADY
    Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    Infect Control Hosp Epidemiol 23:759-69. 2002
    ..Although many catheter-related bloodstream infections (CRBSIs) are preventable, measures to reduce these infections are not uniformly implemented...
  16. ncbi Complications of central venous catheterization
    Roberto E Kusminsky
    Department of Surgery, West Virginia University, Robert C Byrd Health Sciences Center, Charleston Division and Charleston Area Medical Center, Charleston, WV 25304, USA
    J Am Coll Surg 204:681-96. 2007
  17. ncbi Complications of central venous catheters: internal jugular versus subclavian access--a systematic review
    Sibylle Ruesch
    Division of Anaesthesiology, Department Anaesthesiology, Pharmacology, and Surgical Intensive Care, University Hospitals of Geneva, Geneva, Switzerland
    Crit Care Med 30:454-60. 2002
    ..To test whether complications happen more often with the internal jugular or the subclavian central venous approach...
  18. ncbi To reduce catheter-related bloodstream infections: is the subclavian route better than the jugular route for central venous catheterization?
    Goro Nagashima
    Department of Neurosurgery, Fujigaoka Hospital, Showa University, 1 30 Fujigaoka, Aoba ku, Yokohama 227 8501, Japan
    J Infect Chemother 12:363-5. 2006
    ..6 for subclavian and 4.6 for jugular catheterization in noncritical-care departments. Considering complications such as pneumothorax, CV catheterization of the jugular vein is recommended in certain situations...
  19. ncbi A randomized trial comparing povidone-iodine to a chlorhexidine gluconate-impregnated dressing for prevention of central venous catheter infections in neonates
    J S Garland
    St Joseph s Hospital, Milwaukee, WI 53210, USA
    Pediatrics 107:1431-6. 2001
    ..Neonates who require a central venous catheter (CVC) for prolonged vascular access experience high rates of catheter-related bloodstream infection (CRBSI)...
  20. ncbi Video analysis of accidental arterial cannulation with dynamic ultrasound guidance for central venous access
    Michael Blaivas
    Department of Emergency Medicine, Northside Hospital Forsyth, Cumming, GA 30041, USA
    J Ultrasound Med 28:1239-44. 2009
    ..Although accidental arterial penetration with the needle may occur periodically without notice and with little harm, actual arterial dilation and line placement may result in serious complications...
  21. pmc Healthcare-associated infections in pediatric cancer patients: results of a prospective surveillance study from university hospitals in Germany and Switzerland
    Arne Simon
    Pediatric Hematology and Oncology, University Children s Hospital, Bonn, Germany
    BMC Infect Dis 8:70. 2008
    ..Pediatric cancer patients face an increased risk of healthcare-associated infection (HAI). To date, no prospective multicenter studies have been published on this topic...
  22. ncbi The promise of novel technology for the prevention of intravascular device-related bloodstream infection. I. Pathogenesis and short-term devices
    Christopher J Crnich
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, Madison, WI, USA
    Clin Infect Dis 34:1232-42. 2002
    ..The challenge for the future will be to identify new preventative technologies and to begin to adapt more widely those technologies already shown to be efficacious and cost-effective...
  23. ncbi Trends but not individual values of central venous oxygen saturation agree with mixed venous oxygen saturation during varying hemodynamic conditions
    Michael H Dueck
    Department of Anesthesiology, University of Cologne, Cologne, Germany
    Anesthesiology 103:249-57. 2005
    ..The inconsistency of study results may result from different study designs and different, partly questionable, statistical approaches...
  24. ncbi The effectiveness and cost-effectiveness of ultrasound locating devices for central venous access: a systematic review and economic evaluation
    N Calvert
    School of Health and Related Research, University of Sheffield, Sheffield, UK
    Health Technol Assess 7:1-84. 2003
  25. ncbi Right internal jugular vein is recommended for central venous catheterization
    Mitsuru Ishizuka
    Department of Gastroenterological Surgery, Dokkyo Medical University, Mibu, Tochigi, Japan
    J Invest Surg 23:110-4. 2010
    ....
  26. ncbi Preventing complications of central venous catheterization
    David C McGee
    Division of Pulmonary and Critical Care Medicine, Stanford University School of Medicine, Stanford, Calif, USA
    N Engl J Med 348:1123-33. 2003
  27. ncbi Impact of short-term hemodialysis catheters on the central veins: a catheter venographic study
    Levent Oguzkurt
    Department of Radiology, Adana Medical Center, Baskent University, Dadaloglu Mah 39 Sok No 6, Yuregir, Adana 01250, Turkey
    Eur J Radiol 52:293-9. 2004
    ..To determine the incidence of pericatheter sleeve formation, thrombus formation, and stenosis of the central veins in hemodialysis patients with temporary catheters...
  28. ncbi Relationship between chest port catheter tip position and port malfunction after interventional radiologic placement
    Jakob C L Schutz
    Department of Radiology, University of Pennsylvania Medical Center, 1 Silverstein, 3400 Spruce Street, Philadelphia, Pennsylvania 19104, USA
    J Vasc Interv Radiol 15:581-7. 2004
    ..The relationship between catheter tip position of implanted subcutaneous chest ports and subsequent port malfunction was investigated. Tip movement from initial supine position to subsequent erect position was also evaluated...
  29. ncbi Ultrasound guidance for vascular access
    Paul André C Abboud
    Department of Emergency Medicine, Kaiser Permanente Medical Center Oakland, 280 West MacArthur Boulevard, Oakland, CA 94611, USA
    Emerg Med Clin North Am 22:749-73. 2004
    ..Many different techniques may be applied, depending on the clinical situation and equipment available...
  30. ncbi Ultrasound for central venous cannulation: economic evaluation of cost-effectiveness
    N Calvert
    School of Health and Related Research, Regent Court, Regent Street, Sheffield S1 4DA, UK
    Anaesthesia 59:1116-20. 2004
    ..Ultrasound guidance used in central venous cannulation procedures saves NHS resources even with conservative modelling assumptions...
  31. ncbi Inadvertent carotid artery cannulation during ultrasound guided central venous catheterization
    Michael B Stone
    Ann Emerg Med 49:720. 2007
  32. ncbi Central venous catheterization: a prospective, randomized, double-blind study
    Mervyn Mer
    Department of Medicine, Division of Pulmonology and Critical Care, Johannesburg Hospital and University of the Witwatersrand, Johannesburg, South Africa
    Clin Appl Thromb Hemost 15:19-26. 2009
    ..There was no clinical evidence of thrombotic complication in either of the study groups. This study offers direction for the use of CVCs in critically ill patients and addresses many of the controversies that exist...
  33. ncbi Percutaneous placement of central venous catheters: comparing the anatomical landmark method with the radiologically guided technique for central venous catheterization through the internal jugular vein in emergent hemodialysis patients
    M Koroglu
    Department of Radiology, Isparta, Turkey
    Acta Radiol 47:43-7. 2006
    ....
  34. ncbi Bacillus cereus central line infection in an immunocompetent child with hemophilia
    Poyyapakkam R Srivaths
    Tulane University School of Medicine, Huey P Long Medical Center, Department of Pediatrics, New Orleans, Louisiana, USA
    J Pediatr Hematol Oncol 26:194-6. 2004
    ..The authors report a case of Bacillus cereus infection of a central line in an immunocompetent patient with hemophilia, which required line removal for complete cure...
  35. ncbi Head position for facilitating the superior vena caval placement of catheters during right subclavian approach in children
    Chul Woo Jung
    Department of Anesthesiology and Clinical Research Institute, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea
    Crit Care Med 30:297-9. 2002
    ..To evaluate the effect of head position as a method to facilitate the superior vena caval placement of catheters during right subclavian catheterization in children...
  36. ncbi Ultrasound-guided internal jugular venous cannulation in infants: a prospective comparison with the traditional palpation method
    S T Verghese
    Department of Anesthesiology, Children s National Medical Center and George Washington University, Washington, DC 20010, USA
    Anesthesiology 91:71-7. 1999
    ..In this prospective study, the authors tested their hypothesis that using an ultrasound scanner would increase the success of internal jugular cannulation and decrease the incidence of carotid artery puncture in infants...
  37. ncbi Central venous catheterization and fatal cardiac tamponade
    S A Booth
    Department of Anaesthesia, Addenbrooke's Hospital, Hills Road, Cambridge CB2 2QQ, UK
    Br J Anaesth 87:298-302. 2001
    Cardiac tamponade is a poorly recognized complication of central venous catheterization associated with a high mortality...
  38. ncbi Eliminating arterial injury during central venous catheterization using manometry
    Catalin S Ezaru
    Department of Anesthesiology, 3A101, Veterans Affairs Medical Center, University of Pittsburgh School of Medicine, University Dr C, Pittsburgh, PA 15240, USA
    Anesth Analg 109:130-4. 2009
    ..1%-0.5% of patients. Routine performance of manometry during catheterization may successfully identify unintended arterial puncture and avoid arterial cannulation and injury...
  39. ncbi Comparison between the jugular and subclavian vein as insertion site for central venous catheters: microbiological aspects and risk factors for colonization and infection
    Geraldo Sadoyama
    Laboratory of Microbiology ARIMP Federal University of Uberlândia, Uberlandia MG, Brazil
    Braz J Infect Dis 7:142-8. 2003
    ..Health professionals should be aware of this potential source of infection at the CVC insertion site...
  40. ncbi [Chylothorax after central venous catheterization. Considerations to anatomy, differential diagnosis and therapy]
    W Schummer
    Klinik für Anästhesiologie und Intensivtherapie, Friedrich Schiller Universitat Jena
    Anaesthesist 52:919-24. 2003
    ..Likewise described are pathophysiology, signs, clinical features, and differential diagnosis with special consideration of the triglyceride content as well as treatment options...
  41. ncbi Long-term central venous catheterization via persistent left superior vena cava: a case report
    Lamberto Laurenzi
    Department of Pain Therapy and Palliative Care, Regina Elena National Cancer Institute, Via Elio Chianesi, 53, 00141 Rome, Italy
    Support Care Cancer 11:190-2. 2003
    ..The patient died after 8 months of this therapy. No complications attributable to the catheter were observed. We think that the risk is acceptable in similar conditions...
  42. ncbi Uses and complications of central venous catheters inserted in a pediatric emergency department
    V W Chiang
    Division of Emergency Medicine, Children s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Pediatr Emerg Care 16:230-2. 2000
    ..To describe the incidence, indications, insertion sites, duration, and complications of central venous catheter (CVC) insertion in patients in a pediatric emergency department (ED)...
  43. ncbi The accuracy of the central landmark used for central venous catheterization of the internal jugular vein
    Peter L Bailey
    Department of Anesthesiology, University of Rochester, Rochester, New York, USA
    Anesth Analg 102:1327-32. 2006
    We simulated needle paths based on the central landmark used for central venous catheterization of the internal jugular vein...
  44. ncbi Bacterial biofilms: a diagnostic and therapeutic challenge
    Christoph A Fux
    Center for Biofilm Engineering, Montana State University, USA
    Expert Rev Anti Infect Ther 1:667-83. 2003
    ..This review discusses the shortcomings of current therapies against biofilms both in theory and with clinical examples. Biofilm characteristics are described with a focus on new diagnostic and therapeutic targets...
  45. ncbi Visualisation of needle position using ultrasonography
    G A Chapman
    Anaesthesia and Intensive Care, The General Infirmary at Leeds, Leeds, UK
    Anaesthesia 61:148-58. 2006
    ..A lack of understanding, with regard to imaging the location of the needle tip remains a major obstacle. Needle visualisation and related topics form the basis for this review...
  46. ncbi Guidelines for the prevention of intravascular catheter-related infections. The Hospital Infection Control Practices Advisory Committee, Center for Disease Control and Prevention, U.S
    NAOMI P O'GRADY
    National Institutes of Health, Department of Critical Care Medicine, Bethesda, Maryland 20892, USA
    Pediatrics 110:e51. 2002
    ..These guidelines also identify performance indicators that can be used locally by health-care institutions or organizations to monitor their success in implementing these evidence-based recommendations...
  47. ncbi Evaluation of outcome of intravenous catheter-related infections in critically ill patients
    J Rello
    Intensive Care, Internal Medicine, Microbiology and Epidemiology Departments, Parc Taulí Health Corporation, Sabadell, Barcelona, Spain
    Am J Respir Crit Care Med 162:1027-30. 2000
    ..Nevertheless, these infections lead to an increase in hospital stay of approximately 20 d. Each episode of CRI represents an additional cost of more than 3,000 Euros...
  48. ncbi Outcomes of primary and catheter-related bacteremia. A cohort and case-control study in critically ill patients
    B Renaud
    , , , , France
    Am J Respir Crit Care Med 163:1584-90. 2001
    ..Differentiating catheter-related bacteremia from both primary and other secondary bacteremia appears warranted in studies conducted in critically ill patients...
  49. ncbi Taurolidine is effective in the treatment of central venous catheter-related bloodstream infections in cancer patients
    M Koldehoff
    Department of Bone Marrow Transplantation, University Hospital Essen, Hufelandstreet 55, 45122 Essen, Germany
    Int J Antimicrob Agents 24:491-5. 2004
    ..v. lock for the therapy of catheter-related bloodstream infections in oncological patients. Taurolidine i.v. lock application is feasible and could especially be useful in infections resistant to antibiotic chemotherapy...
  50. ncbi Blood products: a significant risk factor for long-term catheter-related bloodstream infections in cancer patients
    H A Hanna
    University of Texas M.D. Anderson Cancer Center, Section of Infection Control, Houston 77030, USA
    Infect Control Hosp Epidemiol 22:165-6. 2001
    ..through central venous catheters was a risk factor for CR BSI, whereas thrombocytopenia during catheterization may have provided protection against CR BSI, as did central venous catheter insertion under maximal sterile barrier precautions..
  51. ncbi Nonuniform risk of bloodstream infection with increasing central venous catheter-days
    Mary Louise McLaws
    NSW Hospital Infection Epidemiology and Surveillance Unit, School of Public Health and Community Medicine, Faculty of Medicine, University of New South Wales, Sydney, Australia
    Infect Control Hosp Epidemiol 26:715-9. 2005
    ..To determine whether the conventional rate for central venous catheter (CVC)-associated bloodstream infection (BSI) accurately reflects risk for patients exposed for a variety of in situ periods...
  52. ncbi Ultrasound-guided central venous cannulation in infants and children
    P Asheim
    Department of Anesthesia and Intensive Care, Trondheim University Hospital, Trondheim, Norway
    Acta Anaesthesiol Scand 46:390-2. 2002
    ..An ultrasound-guided technique is now available and we wanted to evaluate this method in children and infants, looking specifically at the ease of use, success rate and complications...
  53. ncbi The effects of the simulated Valsalva maneuver, liver compression, and/or Trendelenburg position on the cross-sectional area of the internal jugular vein in infants and young children
    Susan T Verghese
    Department of Anesthesiology, Children s National Medical Center and George Washington University Medical Center, Washington, DC 20010, USA
    Anesth Analg 94:250-4, table of contents. 2002
    ..001 and Wilcoxon's test, P < 0.002). As a single maneuver, V produced the most increase (40.4% +/- 32.2%) compared with L compression (14.3% +/- 18.9%) or T position (24.3% +/- 27.1%)...
  54. ncbi Vascular access survival in children and young adults receiving long-term hemodialysis
    Ian J Ramage
    Renal Unit, Royal Hospital for Sick Children, Glasgow, Scotland
    Am J Kidney Dis 45:708-14. 2005
    ..The aim of this study is to compare CVL, AVF, and AVG survival and determine factors affecting their survival...
  55. ncbi Persistent left superior vena cava: an incidental finding during central venous catheterization-a case report
    Payman J Danielpour
    Mount Sinai Medical Center, Department of Surgery, Miami Beach, Florida 33140, USA
    Vasc Endovascular Surg 39:109-11. 2005
    ..PLSVC is most often discovered subsequent to central venous or pulmonary artery catheter placement...
  56. ncbi Comparison of vascular access type in pediatric hemodialysis patients with respect to urea clearance, anemia management, and serum albumin concentration
    Deepa H Chand
    Section of Pediatric Nephrology and Hypertension, Children s Hospital Cleveland Clinic, Cleveland, OH, USA
    Am J Kidney Dis 45:303-8. 2005
    ....
  57. ncbi Intra-atrial ECG is not a reliable method for positioning left internal jugular vein catheters
    W Schummer
    Department of Anaesthesiology and Intensive Care Medicine, Friedrich Schiller University of Jena, Bachstrasse 18, D 07743 Jena, Germany
    Br J Anaesth 91:481-6. 2003
    ..To investigate the value of left-sided ECG guidance, we performed this prospective study...
  58. ncbi The pathogenesis of catheter-related bloodstream infection with noncuffed short-term central venous catheters
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, Medical School, University of Wisconsin, Madison, WI 53792, USA
    Intensive Care Med 30:62-7. 2004
    ..We report a prospective study undertaken to determine the pathogenesis of CVC-related BSI...
  59. ncbi A prospective, randomized, double-blind crossover study on the use of 5% citrate lock versus 10% citrate lock in permanent hemodialysis catheters
    Gert Meeus
    Department of Nephrology and Renal Transplantation, University Hospitals Leuven, University of Leuven, Leuven, Belgium
    Blood Purif 23:101-5. 2005
    ....
  60. ncbi Randomized placebo-controlled study of low-dose warfarin for the prevention of central venous catheter-associated thrombosis in patients with cancer
    Stephen Couban
    Department of Medicine, Dalhousie University and Queen Elizabeth II Health Sciences Centre, Room 417, Bethune Bldg, 1278 Tower Rd, Halifax, Nova Scotia B3H 2Y9, Canada
    J Clin Oncol 23:4063-9. 2005
    ..In this multicenter, randomized, placebo-controlled clinical trial, we studied whether warfarin 1 mg daily reduces the incidence of symptomatic central venous catheter (CVC) -associated thrombosis in patients with cancer...
  61. pmc Ultrasonic locating devices for central venous cannulation: meta-analysis
    Daniel Hind
    School of Health and Related Research, Regent Court, Sheffield S1 4DA
    BMJ 327:361. 2003
    ..To assess the evidence for the clinical effectiveness of ultrasound guided central venous cannulation...
  62. ncbi Complications of central venous catheterization in critically ill children
    Bulent Karapinar
    Pediatric Intensive Care Unit, Ege University Faculty of Medicine, Izmir, Turkey
    Pediatr Int 49:593-9. 2007
    ..The purpose of the present paper was to evaluate the success rate, mechanical and thrombotic complications and risk factors associated with these complications from different central venous access sites in critically ill children...
  63. ncbi Catheter-related infection in critically ill patients
    Leonardo Lorente
    Department of Intensive Care, Hospital Universitario de Canarias, Ofra s n La Cuesta, 38320 La Laguna, Santa Cruz de Tenerife, Spain
    Intensive Care Med 30:1681-4. 2004
    ..To describe the incidence of the catheter-related local infection (CRLI) and catheter-related bloodstream infection (CRBSI) of central venous catheters (CVCs) and arterial catheters (ACs)...
  64. ncbi Anti-infective-treated central venous catheters: a systematic review of randomized controlled trials
    B S Niël-Weise
    Dutch Working Party on Infection Prevention, PO Box 9600, 2300 RC Leiden, The Netherlands
    Intensive Care Med 33:2058-68. 2007
    ..This systematic review assesses the effect of anti-infective-treated central venous catheters (CVCs) on catheter-related bloodstream infection (CRBSI) in the acute care setting...
  65. ncbi Intravascular catheter-related infections: new horizons and recent advances
    Issam I Raad
    Department of Infectious Diseases, Infection Control, and Employee Health, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    Arch Intern Med 162:871-8. 2002
    ....
  66. ncbi Experience at a single institution with endovascular treatment of mechanical complications caused by implanted central venous access devices in pediatric and adult patients
    Bertrand Bessoud
    Department of Interventional Radiology, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif, France
    AJR Am J Roentgenol 180:527-32. 2003
    ..Our objective was to describe the technical aspects and evaluate the feasibility, safety, and efficacy of endovascular management of mechanical complications related to implanted central venous devices...
  67. ncbi Acute pulmonary thromboembolism induced by prophylactic heparin use and a heparin-coated catheter: a case of heparin-induced thrombocytopenia and thrombosis syndrome
    Akimitsu Nasuno
    First Department of Internal Medicine, Niigata University Medical Hospital, Japan
    Circ J 67:96-8. 2003
    ..This therapy was successful, and the patient made favorable progress...
  68. ncbi Central venous catheters in pediatric patients--subclavian venous approach as the first choice
    Agop Citak
    Pediatric Emergency Department, Institute of Child Health, University of Istanbul, Istanbul, Turkey
    Pediatr Int 44:83-6. 2002
    ..It is critical to establish a safe and functional i.v. access in severely sick patients. We evaluated the frequency of application and complications of central venous catheters in a pediatric intensive care unit...
  69. pmc Diagnosis, prevention, and management of catheter related bloodstream infection during long term parenteral nutrition
    D Hodge
    Department of Paediatrics, Leeds Teaching Hospitals NHS Trust, Leeds, UK
    Arch Dis Child Fetal Neonatal Ed 87:F21-4. 2002
  70. pmc Impact of emergency intubation on central venous oxygen saturation in critically ill patients: a multicenter observational study
    Glenn Hernandez
    Departamento de Medicina Intensiva, Pontificia Universidad Catolica de Chile, Marcoleta 367, Santiago, Chile
    Crit Care 13:R63. 2009
    ..Therefore, we conducted a study to determine the impact of emergency intubation on ScvO2...
  71. ncbi Guidelines for the prevention of intravascular catheter-related infections
    NAOMI P O'GRADY
    Clinical Center, National Institutes of Health, Bethesda, MD, USA
    Am J Infect Control 30:476-89. 2002
    ..Although many catheter-related bloodstream infections (CR-BSIs) are preventable, measures to reduce these infections are not uniformly implemented...
  72. ncbi Reduction of catheter-related colonisation by the use of a silver zeolite-impregnated central vascular catheter in adult critical care
    Milind D Khare
    Department of Clinical Microbiology, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK
    J Infect 54:146-50. 2007
    ..Larger prospective randomised control studies are required to evaluate its role in the prevention of CR-BSI...
  73. ncbi Use of the right external jugular vein as the preferred access site when the right internal jugular vein is not usable
    Sung Ki Cho
    Department of Radiology, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Ilwon Dong, Kangnam Gu, Seoul 135 710, Korea
    J Vasc Interv Radiol 17:823-9. 2006
    ..The present study describes the authors' experience with central venous access through the right external jugular vein (EJV) when the right internal jugular vein (IJV) is not available...
  74. ncbi Success rates and cost-effectiveness of antibiotic combinations for initial treatment of central-venous-line infections during total parenteral nutrition
    M L Forchielli
    Department of Pediatrics, University of Bologna, Italy
    JPEN J Parenter Enteral Nutr 24:119-25. 2000
    ..This empirical list, however, has never been verified against actual sensitivity results nor has it been tested for cost or efficacy...
  75. ncbi Use of ultrasound to place central lines
    Sean P Keenan
    New Westminster, British Columbia, Canada
    J Crit Care 17:126-37. 2002
    ..The use of real-time ultrasound to guide line placement has been developed in hopes of avoiding this morbidity...
  76. ncbi Effect of covalently bound heparin coating on patency and biocompatibility of long-term indwelling catheters in the rat jugular vein
    Patricia L Foley
    Center for Comparative Medicine, University of Virginia, Charlottesville 22908, USA
    Comp Med 52:243-8. 2002
    ..Taken together, these results indicate that coating catheters with covalently bound heparin molecules can significantly prolong patency and cause less pathologic damage to the catheterized vessel...
  77. ncbi Warfarin thromboprophylaxis in cancer patients with central venous catheters (WARP): an open-label randomised trial
    Annie M Young
    Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, UK
    Lancet 373:567-74. 2009
    ..We therefore assessed whether warfarin reduces catheter-related thrombosis compared with no warfarin and whether the dose of warfarin determines the thromboprophylactic effect...
  78. ncbi Central venous catheter-related complications in children with oncological/hematological diseases: an observational study of 418 devices
    G Fratino
    Department of Pediatric Surgery, G Gaslini Children s Hospital, Genoa, Italy
    Ann Oncol 16:648-54. 2005
    ..We describe the experience of two tertiary care centers in Italy that prospectively followed up three types of CVC used at both institutions over a 30-month period...
  79. ncbi Infectious complications of percutaneous central venous catheterization in pediatric patients: a Spanish multicenter study
    M Angeles García-Teresa
    Pediatric Intensive Care Unit, Hospital Nino Jesus, C Menéndez Pelayo, 65, 28009, Madrid, Spain
    Intensive Care Med 33:466-76. 2007
    ..Analysis of infectious complications and risk factors in percutaneous central venous catheters...
  80. ncbi Central venous catheterization--an anatomical review of a clinical skill. Part 2. Internal jugular vein via the supraclavicular approach
    J M Boon
    Department of Anatomy, University of Pretoria, Pretoria, South Africa
    Clin Anat 21:15-22. 2008
    The safe and successful performance of a central venous catheterization (CVC) requires a specific knowledge of anatomy in addition to a working knowledge. Misunderstanding the anatomy may result in failure or complications...
  81. pmc Pleural drainage using central venous catheters
    Kulgit Singh
    Consultant, Department of Anaesthesiology, Tan Tock Seng Hospital, Singapore
    Crit Care 7:R191-4. 2003
    ..The objective of the present study was to evaluate the use of a single lumen 16 G central venous catheter for the drainage of uncomplicated pleural effusions in intensive care unit patients...
  82. ncbi Clinical applicability of the substitution of mixed venous oxygen saturation with central venous oxygen saturation
    S Turnaoğlu
    Department of Anesthesiology, Istanbul University, Istanbul Medical Faculty, Istanbul, Turkiye
    J Cardiothorac Vasc Anesth 15:574-9. 2001
    ..To examine the clinical applicability of substituting central venous oxygen saturation (ScvO2) for mixed venous oxygen saturation (SmvO2) in monitoring global tissue oxygenation...
  83. ncbi Videos in clinical medicine. Central venous catheterization--subclavian vein
    Dana A V Braner
    Department of Pediatrics, Oregon Health and Science University, Portland, OR 97239, USA
    N Engl J Med 357:e26. 2007
  84. ncbi Effect of a second-generation venous catheter impregnated with chlorhexidine and silver sulfadiazine on central catheter-related infections: a randomized, controlled trial
    Mark E Rupp
    University of Nebraska Medical Center, Omaha, Nebraska, USA
    Ann Intern Med 143:570-80. 2005
    ..Central venous catheter-related infections are a significant medical problem. Improved preventive measures are needed...
  85. ncbi Influence of prolonged use of intravenous administration sets in paediatric cancer patients on CVAD-related bloodstream infection rates and hospital resources
    A Simon
    Dept of Paediatric Hematology and Oncology, Children s Hospital, Medical Center, University of Bonn, Adenauerallee 119, 53113, Bonn, Germany
    Infection 34:258-63. 2006
    ....
  86. pmc Incidence of low central venous oxygen saturation during unplanned admissions in a multidisciplinary intensive care unit: an observational study
    Hendrik Bracht
    Department of Intensive Care Medicine, University Hospital Bern, University of Bern, Freiburgstrasse, CH 3010 Bern, Switzerland
    Crit Care 11:R2. 2007
    ..The early ScvO2 profile of other patient groups is unknown. The aim of this study was to characterize unplanned admissions in a multidisciplinary intensive care unit (ICU) with respect to ScvO2 and outcome...
  87. ncbi Central venous catheter-related blood stream infections: incidence, risk factors, outcome, and associated pathogens
    Mandakini Pawar
    Department of Microbiology, Escorts Heart Institute and Research Centre, New Delhi, India
    J Cardiothorac Vasc Anesth 18:304-8. 2004
    ..To determine the incidence, risk factors, outcome, and pathogens of central venous catheter-related bloodstream infections (CVC-BSIs)...
  88. ncbi Continuous central venous and pulmonary artery oxygen saturation monitoring in the critically ill
    Konrad Reinhart
    Department of Anesthesia and Intensive Care Medicine, Friedrich Schiller University, Erlanger Allee 101, 07747 Jena, Germany
    Intensive Care Med 30:1572-8. 2004
    ..To compare the course of continuously measured mixed and central venous O(2) saturations in high-risk patients and to evaluate the impact of various factors that might interfere with reflection spectrophotometry...
  89. ncbi Diagnosis and treatment of catheter-related infections in paediatric oncology: an update
    A Simon
    Department of Paediatric Haematology and Oncology, Children s Hospital Medical Centre, University of Bonn, Bonn, Germany
    Clin Microbiol Infect 12:606-20. 2006
    ..Although prospectively controlled studies are lacking, the concomitant use of urokinase locks and taurolidine secondary prophylaxis seem to favour catheter salvage...
  90. ncbi Central venous lines for chronic hemodialysis: survey of the Midwest Pediatric Nephrology Consortium
    Rudolph P Valentini
    Division of Nephrology, The Carman and Ann Adams Department of Pediatrics, Children s Hospital of Michigan, Wayne State University School of Medicine, Detroit, MI, USA
    Pediatr Nephrol 23:291-5. 2008
    ..As treatment strategies varied greatly, future prospective studies are needed to determine the effectiveness of each individual therapy...
  91. ncbi Risk of catheter-related bloodstream infection with peripherally inserted central venous catheters used in hospitalized patients
    Nasia Safdar
    Section of Infectious Diseases, Department of Medicine, University of Wisconsin Medical School, Madison, USA
    Chest 128:489-95. 2005
    ..Data on the risk of PICC-related bloodstream infection (BSI) with PICCs used in hospitalized patients are limited...
  92. ncbi Catheter lock solutions: it's time for a change
    S Mandolfo
    Renal Unit, Maggiore Hospital, Lodi, Italy
    J Vasc Access 7:99-102. 2006
    ....
  93. ncbi Use of central venous catheter-related bloodstream infection prevention practices by US hospitals
    Sarah L Krein
    Center for Practice Management and Outcomes Research, Veterans Affairs Ann Arbor Healthcare System, Ann Arbor, Michigan, USA
    Mayo Clin Proc 82:672-8. 2007
    ..To examine the extent to which US acute care hospitals have adopted recommended practices to prevent central venous catheter-related bloodstream infections (CR-BSIs)...
  94. ncbi Right subclavian catheter perforation of the aorta due to an incorrect external landmark-guided insertion technique
    Rune Haaverstad
    Department of Cardiothoracic Surgery, University Hospital of Wales, Cardiff, United Kingdom
    CJEM 9:43-5. 2007
    ..A standardized approach for all central venous line insertions should be emphasized for all clinicians. Use of ultrasound guidance whenever feasible is encouraged...
  95. ncbi Diagnosis of catheter-related bloodstream infections among pediatric oncology patients lacking a peripheral culture, using differential time to detection
    Aditya H Gaur
    Department of Infectious Diseases, St Jude Children s Research Hospital, Memphis, TN 38105 2794, USA
    Pediatr Infect Dis J 24:445-9. 2005
    ..Both the pain and inconvenience of PV cultures are undesirable...
  96. ncbi Intravenous morphine and topical tetracaine for treatment of pain in [corrected] neonates undergoing central line placement
    Anna Taddio
    Department of Pharmacy, The Hospital for Sick Children, Faculty of Pharmaceutical Sciences, University of Toronto, Toronto, Ontario
    JAMA 295:793-800. 2006
    ..There is limited evidence of the analgesic effectiveness of opioid analgesia or topical anesthesia during central line placement in neonates, and there are no previous studies of their relative effectiveness...
  97. ncbi ECG recording of central venous catheter misplaced in inferior thyroid artery
    W Schummer
    Department of Anaesthesiology and Intensive Care Medicine, Friedrich Schiller University, Erlanger Allee 103, 07747 Jena, Germany
    Br J Anaesth 94:296-9. 2005
    ..A thrill was felt. The management of this case is discussed, with suggestions for best practice. Intravascular ECG was unhelpful in differentiating between venous and arterial placement of the catheter...
  98. ncbi Ultrasound guidance during central venous catheterization: a survey of use by house staff physicians
    Timothy D Girard
    Division of Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, TN 37232 8300, USA
    J Crit Care 20:224-9. 2005
    ..The objective of this study is to explore the attitudes, knowledge, and behavior of house staff physicians regarding the use of ultrasound guidance (UG) during central venous catheter placement (CP)...
  99. ncbi Videos in clinical medicine. Central venous catheterization
    Alan S Graham
    Department of Pediatrics, Division of Pediatric Critical Care, Doernbecher Children s Hospital, Portland, OR 97239 2901, USA
    N Engl J Med 356:e21. 2007
  100. ncbi A randomized, controlled trial of a new vascular catheter flush solution (minocycline-EDTA) in temporary hemodialysis access
    Anthony J Bleyer
    Department of Internal Medicine, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    Infect Control Hosp Epidemiol 26:520-4. 2005
    ..This study compared heparin with minocycline-EDTA as flush solutions used among dialysis patients with central venous catheters, a high-risk group for catheter-related BSI...
  101. ncbi A prospective, randomized trial of rifampicin-minocycline-coated and silver-platinum-carbon-impregnated central venous catheters
    David Fraenkel
    Department of Intensive Care, Princess Alexandra Hospital, and School of Population Health, University of Queensland, Australia
    Crit Care Med 34:668-75. 2006
    ..We compared the infection rate of silver-platinum-carbon (SPC)-impregnated catheters with rifampicin-minocycline (RM)-coated catheters...

Research Grants44

  1. Protocolized Care for Early Septic Shock (ProCESS)
    Derek C Angus; Fiscal Year: 2012
    ..are generalizable and whether all elements of the protocol are necessary, especially the use of central venous catheterization and blood transfusion...
  2. Silver coatings to combat catheter associated infections
    Bruce Gibbins; Fiscal Year: 2006
    ..Those that occur with central venous catheterization escalate the cost to between $35,000 and $50,000 per infection, with a mortality rate that exceeds 35%...
  3. Resonance Driven Vascular Entry Needle to Reduce Insertion Forces
    DEBORA DEMERS; Fiscal Year: 2009
    ..PRII will optimize and test a prototype to reduce the insertion force necessary for central venous catheterization (CVC), venipuncture, and other difficult vein access procedures. For certain patients (e.g...
  4. Rapid Detection of Catheter Related Bacteraemia
    XING XIANG LI; Fiscal Year: 2005
    b>Central venous catheterization is an essential part of intensive care and cancer patient care. Approximately 5 million central venous catheters are used each year in the U.S., and the number is expected to rise due to aging population...
  5. Pheresis Treatment of Bioterrorism-Induced Sepsis
    Stephen Ash; Fiscal Year: 2005
    ..The safety systems of the existing PF system will be modified to meet the needs of the stand-alone system. Finally, an animal model of sepsis will be used to check efficacy and safety of the entire system. ..
  6. MethLock vs. heparin as dialysis catheter lock
    Stephen Ash; Fiscal Year: 2008
    ..In Phase II we will implement the protocol in a number of dialysis centers and complete the study as originally proposed or as modified after Phase I. ..
  7. Prevention of Catheter-Associated Blood Stream Infections
    David Warren; Fiscal Year: 2007
    ..I will build on the experience outlined in this proposal to establish myself an independent investigator in healthcare epidemiology, studying nosocomial infections and developing interventions to prevent them. [unreadable] [unreadable]..
  8. Simulation Training for Ultrasound Guided Central Venous Catheter Insertion
    LEIGH EVANS; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  9. High Dose Erythropoetin Neuroprotection Trial for Neonatal Cardiac Surgery
    Dean Andropoulos; Fiscal Year: 2008
    ..This study will show if babies that are given erythropoetin have fewer delays in development than babies that do not receive the drug. [unreadable] [unreadable] [unreadable]..
  10. THE CLOUD ADULT
    Robert Sherertz; Fiscal Year: 2003
    ..aureus associated with a viral URI, have been shown to cause outbreaks. Understanding the "cloud phenomenon" may facilitate S.aureus outbreak prevention and possibly the transmission of other pathogens, as well. ..
  11. Prevention of UTI in persons with spinal cord injury
    Rabih Darouiche; Fiscal Year: 2007
    ..The PIs propose a prospective, randomized, double-blind placebo-controlled multicenter trial to evaluate the clinical efficacy of this innovative therapeutic protocol. [unreadable] [unreadable]..
  12. PICU Nosocomial Infections: Epidemiology and Outcomes
    Alexis Elward; Fiscal Year: 2007
    ....
  13. Cardiopulmonary Exercise Testing: Pulmonary Hypertension
    Ronald Oudiz; Fiscal Year: 2007
    .._l.Center. PHS 398/2590(Rev.05/01) Page _, LJ ContinuationFormatPage NumberpagesconsecutivelyatthebottomthroughoutheapplicationD. o no_u_stesuffixesuchas3a, 3b. ..
  14. Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB Infections
    Lisa Saiman; Fiscal Year: 2009
    ..Carefully conducted observational studies and clinically relevant in vitro antimicrobial susceptibility testing, hold the greatest promise to improve the treatment of patients infected with mutidrug-resistant organisms. ..
  15. Decisionmaking in Pediatric Palliative Care
    JOHN FEUDTNER; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  16. Enhancement of antimicrobics by electrical current
    Robin Patel; Fiscal Year: 2007
    ..This novel but simple resistance reversing strategy may generalize to a wide variety of antimicrobics and microorganisms and a wide variety of biofilm-associated human infections. [unreadable] [unreadable] [unreadable] [unreadable]..
  17. Patient-Centeredness in Care of Vulnerable Populations
    Mary Catherine Beach; Fiscal Year: 2007
    ..abstract_text> ..
  18. Detection of Biofilm Bacteria using GloBac
    Robin Patel; Fiscal Year: 2008
    ..The goal of the proposed studies is to develop a rapid test for detection of bacteria on artificial joints that can be used in the operating room to diagnose infected artificial joints. [unreadable] [unreadable] [unreadable]..
  19. Prospective Investigation for Pulmonary Embolism Dx III
    Paul Stein; Fiscal Year: 2008
    ..abstract_text> ..
  20. STAT3 in the Pathogenesis and Treatment of Pancreatic Cancer
    David Frank; Fiscal Year: 2007
    ..We will test these drugs to determine whether they can be prototypes for a novel targeted form of therapy for this disease. [unreadable] [unreadable] [unreadable]..
  21. PEDIATRIC ONCOLOGY GROUP STUDIES
    Thomas McLean; Fiscal Year: 2002
    ....
  22. PROSPECTIVE INVESTIGATION OF PULMONARY EMBOLISM DX-II
    Paul Stein; Fiscal Year: 2003
    ..4) The team of investigators is strong, and has collaborated previously in successful research in PE. ..
  23. Flow Measurement at Dialysis Access Salvage
    Nikolai Krivitski; Fiscal Year: 2003
    ..We aim to market this device to surgical and interventional radiology and interventional radiology suites worldwide. ..
  24. Psychosocial Influences on Medical Decision Making
    SCOTT ABEREGG; Fiscal Year: 2004
    ..Subsequently (SA#2), we will test the influence of these factors on physician decision making using a case vignette/board examination approach based on Social Judgment Theory. ..
  25. Outcomes in congenital toxoplasmic retinochoroiditis
    Ruth Gilbert; Fiscal Year: 2005
    ..abstract_text> ..
  26. High Throughput Screening for Modulators of STAT5 (RMI)
    David Frank; Fiscal Year: 2004
    ..The ultimate goal is the development of compounds that will act as targeted therapies for human cancers. ..
  27. STAT SIGNALING IN CHRONIC LYMPHOCYTIC LEUKEMIA
    David Frank; Fiscal Year: 2003
    ..As a result of these experiments, we plan to discern the role of STATs in the abnormal growth of CLL cells, and to identify targets for novel and specific therapies. ..
  28. HUMAN RETROVIRUS-5 AND ARTHRITIS
    Robin Patel; Fiscal Year: 2002
    ..Identification of a specific infectious agent associated with these arthritides would potentially allo for the development of preventive strategies such as vaccination and novel therapeutic approaches. ..
  29. Vascular Access in Hemodialysis Patients
    Michael Allon; Fiscal Year: 2005
    ..The applicant will assist the trainees in acquiring the conceptual skills, research experience, and motivation required to pursue a successful career in Academic Nephrology. ..
  30. Pediatric Cardiac Monitor for Extracorporeal Life Support
    Nikolai Krivitski; Fiscal Year: 2005
    ....
  31. PEDIATRIC AIDS CLINICAL TRIALS GROUP
    Patricia Flynn; Fiscal Year: 2006
    ..abstract_text> ..
  32. Clonal Selection in Diabetic Nephropathy
    Oliver Lenz; Fiscal Year: 2003
    ..The long-term goal of our proposal is to characterize the role of clonal selection in glomerular disease, and identify new targets for screening, prevention, and intervention in the pathogenesis of diabetic nephropathy. ..
  33. Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB Infections
    Lisa Maragakis; Fiscal Year: 2009
    ..This research is designed to better understand how providers use information from various microbiology laboratory testing methods to choose treatments and to identify strategies that lead to the best patient outcomes. ..
  34. Fiber Bundle Volume and Clearance During Hemodialysis
    Nikolai Krivitski; Fiscal Year: 2002
    ..This technology will improve hemodialysis outcomes, reduce management costs, and improve the quality of life for hemodialysis patients. A low cost, portable device will be successfully marketable in every hemodialysis center and ICU. ..
  35. Oral Care and Respiratory Pathogen Colonization
    Ozan Akca; Fiscal Year: 2004
    ..Reducing respiratory pathogen colonization in the mouth could significantly reduce the morbidity and cost of VAP. ..
  36. Prevention of Healthcare-Associated Drug-Resistant GNR
    Lisa Maragakis; Fiscal Year: 2006
    ..Maragakis with the skills she needs to develop into an independent clinical investigator in epidemiologic research for the prevention of healthcare-associated infections. ..
  37. RESOLUTION OF CLINICAL LUNG INJURY
    Michael Matthay; Fiscal Year: 2005
    ....
  38. Infection Risk of Urinary Collection Strategies
    Sanjay Saint; Fiscal Year: 2006
    ..Since approximately 40% of elderly Americans will enter a nursing home at some point, identification of those at risk of infection could have considerable health, quality of life, and economic consequences. ..
  39. HEMODIALYSIS VASCULAR ACCESS CLINICAL TRIALS CONSORTIUM
    Michael Allon; Fiscal Year: 2007
    ..The primary endpoint will be fistula thrombosis within 6 weeks, and the secondary endpoint will be the ability to use the fistula successfully for dialysis within 6 months. ..
  40. Role of NOS3 in the Cerebrovascular Response to TBI
    Claudia Robertson; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  41. Midcareer Development in Nonpharmacologic Analgesia
    Elvira Lang; Fiscal Year: 2006
    ..The mentoring of beginning clinical researchers will have contributed towards fostering a self- sustaining mode of integrated practice in the future. ..
  42. ROLE OF ENDOTHELIN IN PERINATAL PULMONARY VASOREGULATION
    DAVID IVY; Fiscal Year: 2002
    ..Research presentations along with graduate level courses in molecular biology, and the clinical ambiance of the Univ of CO SOM in the area of pulmonary hypertension enhance career development. ..
  43. Nisin-based topical formulation for treatment of anthrax
    John Kokai Kun; Fiscal Year: 2003
    ..The final product is intended to minimize the danger for those exposed to B. anthracis and should also be effective for disinfection of other bioterrorism agents and for nosocomial pathogens in the healthcare setting. ..
  44. Medical Maintenance of Hemodialysis Vascular Access (DAC)
    Miguel Vazquez; Fiscal Year: 2006
    ..The health care cost of maintaining adequate vascular access should also decrease from its current rate of over one billion dollars per year. ..