Genomes and Genes
Summary: Use of a balloon catheter for dilatation of an occluded artery. It is used in treatment of arterial occlusive diseases, including renal artery stenosis and arterial occlusions in the leg. For the specific technique of balloon dilatation in coronary arteries, ANGIOPLASTY, TRANSLUMINAL, PERCUTANEOUS CORONARY is available.
Publications251 found, 100 shown here
- Nitinol stent implantation versus balloon angioplasty for lesions in the superficial femoral artery and proximal popliteal artery: twelve-month results from the RESILIENT randomized trialJohn R Laird
Department of Medicine, Division of Cardiovascular Disease, University of California Davis Health System, Sacramento, Calif, USA
Circ Cardiovasc Interv 3:267-76. 2010..There are conflicting data regarding the benefits of superficial femoral artery stenting and the role of primary stenting compared with balloon angioplasty with provisional stent implantation.
- Gene therapy for restenosis after balloon angioplasty and stentingC Indolfi
Division of Cardiology, Federico II, Via Pansini, 5, 80131 Naples, Italy
Cardiol Rev 7:324-31. 1999..Restenosis after balloon angioplasty seems to be determined primarily by the direction and magnitude of vessel wall remodeling...
- Balloon angioplasty versus stenting with nitinol stents in intermediate length superficial femoral artery lesionsPetra Dick
Department of Angiology, Medical University Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria, Europe
Catheter Cardiovasc Interv 74:1090-5. 2009Recent randomized trials investigating stent implantation compared with balloon angioplasty for treatment of superficial femoral artery (SFA) disease have given divergent results in short (mean 5 cm) and intermediate (mean 10 cm) lesions...
- In vivo blockade of tumor necrosis factor-alpha accelerates functional endothelial recovery after balloon angioplastyK Krasinski
Division of Cardiovascular Medicine, St. Elizabeth's Medical Center, Tufts University School of Medicine, Boston, Massachusetts, USA
Circulation 104:1754-6. 2001..These findings suggest that locally expressed TNF acts to inhibit functional endothelial recovery after angioplasty and that transient blockade of TNF may improve the long-term success of angioplasty...
- Balloon angioplasty versus implantation of nitinol stents in the superficial femoral arteryMartin Schillinger
Department of Angiology, Medical University of Vienna, Vienna General Hospital, Vienna, Austria
N Engl J Med 354:1879-88. 2006..We evaluated whether primary implantation of a self-expanding nitinol (nickel-titanium) stent yielded anatomical and clinical benefits superior to those afforded by percutaneous transluminal angioplasty with optional secondary stenting...
- Cathepsin S expression is up-regulated following balloon angioplasty in the hypercholesterolemic rabbitCynthia L Burns-Kurtis
Department of Vascular Inflammatory Diseases, GlaxoSmithKline Pharmaceuticals, 709 Swedeland Road, P O Box 1539, King of Prussia, PA 19406, USA
Cardiovasc Res 62:610-20. 2004Neointimal development following balloon angioplasty involves many factors including smooth muscle cell (SMC) migration and proliferation and extracellular matrix (ECM) remodeling...
- A novel, self-expanding, nitinol stent in medically refractory intracranial atherosclerotic stenoses: the Wingspan studyArani Bose
Lenox Hill Hospital, New York, NY, USA
Stroke 38:1531-7. 2007....
- Inflammatory response to stent implantation: differences in femoropopliteal, iliac, and carotid arteriesMartin Schillinger
Department of Angiology, University of Vienna Medical School, Währinger Gürtel 18 20 6J, 1090 Vienna, Austria
Radiology 224:529-35. 2002..To investigate the postintervention course of serum acute-phase reactants after stent implantation in the femoropopliteal, iliac, and carotid arteries...
- Heme oxygenase-1 genotype and restenosis after balloon angioplasty: a novel vascular protective factorMartin Schillinger
Angiology, Department of Laboratory Medicine, University of Vienna, Medical Faculty, Waehringer Guertel 18 20, A 1090 Vienna, Austria
J Am Coll Cardiol 43:950-7. 2004We investigated the association of the heme oxygenase-1 (HO-1) promoter genotype with the inflammatory response and restenosis after balloon angioplasty.
- Effect of prophylactic transluminal balloon angioplasty on cerebral vasospasm and outcome in patients with Fisher grade III subarachnoid hemorrhage: results of a phase II multicenter, randomized, clinical trialMarike Zwienenberg-Lee
Department of Neurological Surgery, Children s Hospital of Wisconsin, 999 N 92nd St, Suite 310, Milwaukee, WI 53226, USA
Stroke 39:1759-65. 2008..Prophylactic Transluminal Balloon Angioplasty (pTBA) appeared to prevent delayed ischemic neurological deficit in a pilot study...
- Conventional balloon angioplasty versus peripheral cutting balloon angioplasty for treatment of femoropopliteal artery in-stent restenosis: initial experiencePetra Dick
Department of Internal Medicine II, Division of Angiology, Vienna General Hospital, Medical School, Waehringer Guertel 18 20, A 1090 Vienna, Austria
Radiology 248:297-302. 2008To prospectively determine whether cutting balloon angioplasty, when compared with conventional balloon angioplasty (CBA), improves morphologic and clinical outcome in patients with femoropopliteal in-stent restenosis.
- Physical training increases eNOS vascular expression and activity and reduces restenosis after balloon angioplasty or arterial stenting in ratsCiro Indolfi
Division of Cardiology, Magna Graecia University, Catanzaro, Italy
Circ Res 91:1190-7. 2002..In conclusion, physical exercise could favorably affect restenosis after balloon angioplasty and stenting...
- Virus-encoded serine proteinase inhibitor SERP-1 inhibits atherosclerotic plaque development after balloon angioplastyA Lucas
Department of Medicine, University of Alberta, Edmonton, Canada
Circulation 94:2890-900. 1996..the use of a viral serine proteinase inhibitor, SERP-1, to reduce plaque development after primary balloon angioplasty. This is the first experimental report of the use of a viral anti-inflammatory protein for the prevention ..
- Dialysis access venous stenoses: treatment with balloon angioplasty--1- versus 3-minute inflation timesAndrew R Forauer
Department of Vascular and Interventional Radiology, Dartmouth Hitchcock Medical Center, 1 Medical Center Dr, Lebanon, NH 03756, USA
Radiology 249:375-81. 2008To examine prospectively the effects of balloon inflation time on the technical success of balloon angioplasty in dialysis access venous stenosis and on postintervention primary patency.
- Time course and importance of neoadventitial formation in arterial remodeling following balloon angioplasty of porcine coronary arteriesM Labinaz
Department of Medicine, University of Ottawa Heart Institute, Ontario, Canada
Cardiovasc Res 41:255-66. 1999..We hypothesized that arterial remodeling does not occur in all arteries following balloon injury and is dependent on neoadventitial formation...
- Sustained benefit at 2 years of primary femoropopliteal stenting compared with balloon angioplasty with optional stentingMartin Schillinger
Department of Angiology, Medical University, Vienna, Austria
Circulation 115:2745-9. 2007..stents of the superficial femoral artery yielded improved morphological and clinical results compared with balloon angioplasty with optional stenting until 12 months in a randomized controlled trial...
- PDGF-receptor tyrosine kinase blocker AG1295 selectively attenuates smooth muscle cell growth in vitro and reduces neointimal formation after balloon angioplasty in swineS Banai
Heiden Department of Cardiology, Bikur Cholim Hospital, Jerusalem, Israel
Circulation 97:1960-9. 1998....
- Infrapopliteal balloon angioplasty for the treatment of chronic occlusive diseaseMark F Conrad
Division of Vascular and Endovascular Surgery of the General Surgical Services, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
J Vasc Surg 50:799-805.e4. 2009There is little documentation of the effectiveness of percutaneous balloon angioplasty (PTA) of infrapopliteal vessels for the treatment of chronic lower extremity ischemia...
- Bypass versus angioplasty in severe ischaemia of the leg (BASIL): multicentre, randomised controlled trialD J Adam
Lancet 366:1925-34. 2005The treatment of rest pain, ulceration, and gangrene of the leg (severe limb ischaemia) remains controversial. We instigated the BASIL trial to compare the outcome of bypass surgery and balloon angioplasty in such patients.
- Time delay to treatment and mortality in primary angioplasty for acute myocardial infarction: every minute of delay countsGiuseppe De Luca
Department of Cardiology, Isala Klinieken, Zwolle, The Netherlands
Circulation 109:1223-5. 2004..The aim of this report was to address the relationship between time to treatment and mortality as a continuous function and to estimate the risk of mortality for each 30-minute delay...
- A layer-specific three-dimensional model for the simulation of balloon angioplasty using magnetic resonance imaging and mechanical testingGerhard A Holzapfel
Institute for Structural Analysis Computational Biomechanics, Graz University of Technology, Austria
Ann Biomed Eng 30:753-67. 2002A detailed understanding of the mechanical procedure of balloon angioplasty requires three-dimensional (3D) modeling and efficient numerical simulations...
- Evaluation of the safety and effectiveness of renal artery stenting after unsuccessful balloon angioplasty: the ASPIRE-2 studyKrishna Rocha-Singh
Vascular Medicine Program, Prairie Heart Institute, Springfield, Illinois 62794 9420, USA
J Am Coll Cardiol 46:776-83. 2005..This study sought to define the safety and durability of renal stenting after suboptimal/failed renal artery angioplasty in patients with suspected renovascular hypertension...
- Activation of nuclear factor-kappa B significantly contributes to lumen loss in a rabbit iliac artery balloon angioplasty modelJ M Breuss
Department of Vascular Biology and Thrombosis Research, University of Vienna, Austria
Circulation 105:633-8. 2002....
- Is routine stenting for acute myocardial infarction superior to balloon angioplasty? A randomised comparison in a large cohort of unselected patientsH Suryapranata
Department of Cardiology, Isala Klinieken, Hospital De Weezenlanden, Zwolle, The Netherlands
Heart 91:641-5. 2005To evaluate the impact of routine stenting, compared with balloon angioplasty, in unselected patients presenting with ST segment elevation myocardial infarction (STEMI).
- Vascular inflammation and percutaneous transluminal angioplasty of the femoropopliteal artery: association with restenosisMartin Schillinger
Department of Angiology, University of Vienna Medical School, Vienna General Hospital, Währinger Gürtel 18 20 6J, A 1090 Vienna, Austria
Radiology 225:21-6. 2002....
- Increased synthetic phenotype behavior of smooth muscle cells in response to in vitro balloon angioplasty injury modelK Bethany Acampora
Department of Bioengineering, Clemson University, 301 Rhodes Hall, Clemson, SC 29634, USA
Ann Vasc Surg 24:116-26. 2010Restenosis remains a common problem following balloon angioplasty, and it has been speculated that changes in the mechanical environment due to endovascular interventions are correlated with shifts in smooth muscle cell (SMC) phenotype...
- Osteopontin expression in platelet-derived growth factor-stimulated vascular smooth muscle cells and carotid artery after balloon angioplastyX Wang
Department of Cardiovascular Pharmacology, SmithKline Beecham Pharmaceuticals, King of Prussia, PA
Arterioscler Thromb Vasc Biol 16:1365-72. 1996..The temporal expression of OPN mRNA after rat carotid artery balloon angioplasty as assessed by both reverse transcription-polymerase chain reaction and Northern blot analysis revealed a 1...
- Transluminal balloon angioplasty improves brain tissue oxygenation and metabolism in severe vasospasm after aneurysmal subarachnoid hemorrhage: case reportBernd Manfred Hoelper
Department of Neurosurgery, Klinikum Fulda, Academic Hospital of Philips University Marburg, Fulda, Germany
Neurosurgery 52:970-4; discussion 974-6. 2003The effect of transluminal balloon angioplasty on cerebral biochemical monitoring during treatment of severe cerebral vasospasm after subarachnoid hemorrhage (SAH) was investigated.
- Selective alpha(v)beta(3)-receptor blockade reduces macrophage infiltration and restenosis after balloon angioplasty in the atherosclerotic rabbitG G Bishop
University of Virginia, Charlottesville, VA, USA
Circulation 103:1906-11. 2001..We hypothesized that after balloon angioplasty (BA) of atherosclerotic arteries, selective inhibition of the alpha(v)beta(3)-receptor by XT199, a small-..
- [Clinical outcome of percutaneous revascularization by stent-assisted balloon angioplasty of femoro-popliteal and tibial vessels in diabetic patients with critical limb ischemia]Francesco Liistro
Dipartimento Cardiovascolare, Azienda Ospedaliera di Arezzo
G Ital Cardiol (Rome) 10:713-7. 2009..The aim of this study was to assess the long-term clinical outcome of percutaneous peripheral interventions in diabetic patients with critical limb ischemia (CLI) in terms of occurrence of major amputation and mortality...
- Coronary stenting versus balloon angioplasty for acute myocardial infarction: a meta-regression analysis of randomized trialsGiuseppe De Luca
Division of Cardiology, Maggiore della Carita Hospital, Eastern Piedmont University, C so Mazzini, 18, 24100 Novara, Italy
Int J Cardiol 126:37-44. 2008....
- Different inflammatory response and oxidative stress in neointimal hyperplasia after balloon angioplasty and stent implantation in cholesterol-fed rabbitsRiichirou Kawamoto
First Department of Internal Medicine, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889 1692 Japan
Pathol Res Pract 202:447-56. 2006..However, the contribution of C-reactive protein (CRP) and oxidative stress to restenosis after balloon angioplasty and stent implantation remains unclear...
- Prospective trial of infrapopliteal artery balloon angioplasty for critical limb ischemia: angiographic and clinical resultsH K Söder
Department of Clinical Radiology, Kuopio University Hospital, Finland
J Vasc Interv Radiol 11:1021-31. 2000..To evaluate the safety and efficacy of infrapopliteal percutaneous transluminal angioplasty (PTA) as a primary treatment of chronic critical limb ischemia in a prospective trial...
- Severe cerebral vasospasm caused by non-aneurysmal subarachnoid hemorrhage treatment with transluminal balloon angioplastyA Kocak
Inonu University Faculty of Medicine, Department of Neurosurgery, Malatya, Turkey
Minim Invasive Neurosurg 50:23-6. 2007..We report a patient with NSAH who developed severe and diffuse CVS. He was treated with transluminal balloon angioplasty because he has been refractory to conventional treatment measures for CVS.
- Modeling plaque fissuring and dissection during balloon angioplasty interventionT Christian Gasser
Department of Solid Mechanics, School of Engineering Sciences, Royal Institute of Technology KTH, Osquars Backe 1, SE 100 44, Stockholm, Sweden
Ann Biomed Eng 35:711-23. 2007b>Balloon angioplasty intervention is traumatic to arterial tissue. Fracture mechanisms such as plaque fissuring and/or dissection occur and constitute major contributions to the lumen enlargement...
- Balloon angioplasty in the treatment of vascular lesions in pseudoxanthoma elasticumKonstantinos P Donas
J Vasc Interv Radiol 18:457-9. 2007
- Attenuated herpes simplex virus 1 blocks arterial apoptosis and intimal hyperplasia induced by balloon angioplasty and reduced blood flowChristopher L Skelly
Section of Vascular Surgery, Department of Surgery, University of Chicago, Chicago, IL 60637, USA
Proc Natl Acad Sci U S A 104:12474-8. 2007Injury caused by distention of the arterial wall by balloon angioplasty can result in apoptosis and vascular smooth muscle cell proliferation...
- Increased in-stent stenosis in ApoE knockout mice: insights from a novel mouse model of balloon angioplasty and stentingZiad A Ali
Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, OX3 9DU, UK
Arterioscler Thromb Vasc Biol 27:833-40. 2007..We aimed to develop and validate a model of angioplasty and stenting in mice that would allow investigation of the response to stent injury using genetically modified mouse strains...
- Contemporary percutaneous coronary intervention versus balloon angioplasty for multivessel coronary artery disease: a comparison of the National Heart, Lung and Blood Institute Dynamic Registry and the Bypass Angioplasty Revascularization Investigation (BV S Srinivas
Department of Medicine, Division of Cardiovascular Medicine, Albert Einstein College of Medicine Montefiore Medical Center, Bronx, NY, USA
Circulation 106:1627-33. 2002..investigation compares the results of contemporary percutaneous coronary intervention (PCI) with standard balloon angioplasty among patients with multivessel coronary disease...
- Restenosis after percutaneous transluminal angioplasty in the femoropopliteal segment: the role of inflammationM Schillinger
Department of Angiology, University of Vienna Medical School, Austria
J Endovasc Ther 8:477-83. 2001..To determine the value of baseline C-reactive protein (CPR), fibrinogen, and white blood cell (WBC) counts in predicting 1-year patency after percutaneous transluminal angioplasty (PTA) in the femoropopliteal segment...
- Severe aortic coarctation in infants less than 3 months: successful palliation by balloon angioplastyP Syamasundar Rao
Division of Pediatric Cardiology, UT Houston Medical School, 6431 Fannin, Suite 3 132, Houston, TX 77030, USA
J Invasive Cardiol 15:202-8. 2003..We reviewed our experience with balloon angioplasty (BA) in neonates and infants 3 months to test our thesis that BA provides successful palliation, defined ..
- Heme oxygenase-1 genotype is a vascular anti-inflammatory factor following balloon angioplastyMartin Schillinger
Department of Angiology, University of Vienna Medical School, Vienna, Austria
J Endovasc Ther 9:385-94. 2002To investigate the association of the heme oxygenase-1 (HO-1) genotype, which has potent anti-inflammatory capability, and the inflammatory response induced by balloon angioplasty.
- Interventional radiology in hemodialysis fistulae and grafts: a multidisciplinary approachLuc Turmel-Rodrigues
Department of Cardiovascular Radiology, Clinique St Gatien, Place de la Cathedrale, F 37000 Tours, France
Cardiovasc Intervent Radiol 25:3-16. 2002..To review the place of interventional radiology in arteriovenous access for hemodialysis...
- 192Ir endovascular irradiation prevents restenosis after balloon angioplasty in rabbitM Chen
Department of Cardiology, Peking University First Hospital, Beijing 100034, China
Chin Med J (Engl) 114:62-3. 2001OBJECTIVE: To examine the effect of endovascular irradiation on restenosis after balloon angioplasty in rabbit...
- Early outcome of "cutting" balloon angioplasty for infrainguinal vein graft stenosisKarthikeshwar Kasirajan
Department of Surgery, Emory University School of Medicine, Atlanta, GA 30322, USA
J Vasc Surg 39:702-8. 2004..Unlike de novo atherosclerotic lesions, they respond poorly to balloon angioplasty, and may often result in a dissection requiring stent placement to avoid early recurrent thrombosis or open ..
- Radiofrequency thermal balloon angioplasty in an experimental model of peripheral arterial stenosisN Sreeram
Wilhelmina Children s Hospital, Utrecht, The Netherlands NS, Department of Cardiology
Int J Cardiol 74:25-32. 2000To assess the effect of thermal balloon angioplasty on surgically created peripheral arterial stenoses.
- Cutting balloon angioplasty of autogenous infrainguinal bypasses: short-term safety and efficacyRobert Garvin
The Department of Surgery, Division of Vascular Surgery, Western Pennsylvania Hospital, Pittsburgh, PA 15224, USA
J Vasc Surg 46:724-30. 2007This study evaluated the safety and efficacy of cutting balloon angioplasty in the treatment of infrainguinal vein bypass graft stenosis.
- Inhibition of matrix deposition: a new strategy for prevention of restenosis after balloon angioplastyAndreas Backes
Department of Cardiology, Giessen University, Germany
J Cardiovasc Pharmacol 55:213-8. 2010Restenosis after balloon angioplasty or stent placement is characterized by local accumulation of mainly vascular smooth muscle cells and the synthesis of extracellular matrix molecules (ECM)...
- Results after balloon angioplasty or stenting of atherosclerotic subclavian artery obstructionSebastian Sixt
Department of Angiology, Heart Centre, Bad Krozingen, Germany
Catheter Cardiovasc Interv 73:395-403. 2009..The purpose of this study was to evaluate the technical and clinical long-term outcome following either balloon angioplasty (plain balloon angioplasty (PTA)) or stenting.
- The impact of balloon angioplasty on the evolution of vasospasm-related infarction after aneurysmal subarachnoid hemorrhageLeonie Jestaedt
Department of Neuroradiology, University of Heidelberg, Heidelberg, Germany
Neurosurgery 62:610-7; discussion 610-7. 2008..The purpose of this study was to evaluate the frequency of infarction after transluminal balloon angioplasty (TBA) in patients with severe subarachnoid hemorrhage-related vasospasm.
- Cutting balloon angioplasty versus standard balloon angioplasty for failing infra-inguinal vein grafts: comparative study of short- and mid-term primary patency ratesRaghunandan Vikram
Department of Diagnostic Imaging, M D Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, TX 77030, USA
Cardiovasc Intervent Radiol 30:607-10. 2007To evaluate the results of a recent change in practice in our institution using cutting balloon angioplasty instead of standard balloon angioplasty as the primary treatment for failing infra-inguinal vein bypass grafts.
- Percutaneous balloon angioplasty for acute occlusion of intracranial arteriesKoji Tokunaga
Department of Neurological Surgery, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Okayama, Japan
Neurosurgery 67:ons189-96; discussion ons196-7. 2010..The benefits of intravenous thrombolysis for acute ischemic stroke are still limited...
- Effects of balloon angioplasty on perfusion- and diffusion-weighted magnetic resonance imaging results and outcome in patients with cerebral vasospasmJürgen Beck
Department of Neurosurgery and Institute of Neuroradiology, Johann Wolfgang Goethe University, Frankfurt, Germany
J Neurosurg 105:220-7. 2006The aim of this study was to analyze the effects and outcome of transluminal balloon angioplasty (TBA) on brain tissue perfusion by using combined perfusion- and diffusion-weighted (PW/DW) magnetic resonance (MR) imaging in patients with ..
- Comparison of coronary stenting versus conventional balloon angioplasty on five-year mortality in patients with acute myocardial infarction undergoing primary percutaneous coronary interventionRajendra H Mehta
Duke Clinical Research Institute, Durham, North Carolina, USA
Am J Cardiol 96:901-6. 2005Little is known about the influence of stenting versus balloon angioplasty on long-term outcomes (particularly mortality) after primary percutaneous coronary intervention (PCI)...
- Genetic risk for restenosis after coronary balloon angioplastyHideki Horibe
Department of Cardiology, Kosei Hospital, Anjo, Japan
Atherosclerosis 174:181-7. 2004Plain old balloon angioplasty (POBA) is a useful therapeutic strategy especially for angioplasty of small coronary arteries. An association study was performed to identify genes that confer susceptibility to restenosis after POBA...
- Primary balloon angioplasty plus balloon angioplasty maturation to upgrade small-caliber veins (<3 mm) for arteriovenous fistulasLorena P De Marco Garcia
Department of Vascular Surgery, North Shore Long Island Jewish Health System, Manhasset, NY 11030, USA
J Vasc Surg 52:139-44. 2010..This study evaluated the use of intraoperative primary balloon angioplasty (PBA) as a technique to upgrade small-diameter veins during AVF creation...
- Subintimal recanalization of long superficial femoral artery occlusions through the retrograde popliteal approachS Yilmaz
Department of Radiology, Akdeniz University School of Medicine, Arapsuyu 07070, Antalya, Turkey
Cardiovasc Intervent Radiol 24:154-60. 2001..To investigate the value of the retrograde popliteal artery approach for the percutaneous intentional extraluminal recanalization (PIER) of long superficial femoral artery (SFA) occlusions...
- Effect of anti-tumor necrosis factor-alpha polyclonal antibody on restenosis after balloon angioplasty in a rabbit atherosclerotic modelZhongmin Zhou
Department of Cardiology, The Cleveland Clinic Foundation, Desk F25, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Atherosclerosis 161:153-9. 2002Inflammation has been postulated to contribute to restenosis after balloon angioplasty. Tumor necrosis factor (TNF)-alpha is a pleiotropic proinflammatory cytokine involved in many features of inflammation...
- Balloon angioplasty for recurrent coarctation of the aorta in patients following staged palliation for hypoplastic left heart syndromeT M Zellers
Department of Pediatrics, University of Texas Southwestern Medical Center at Dallas, 75235, USA
Am J Cardiol 84:231-3, A9. 1999..for hypoplastic left heart syndrome, recurrent coarctation occurred in 9 of 25 survivors (36%) requiring balloon angioplasty, predominantly from a prograde approach...
- Treatment of posterior circulation ischemia with extracranial percutaneous balloon angioplasty and stent placementA M Malek
Department of Radiology, Division of Interventional Neurovascular Radiology, University of California, San Francisco, USA
Stroke 30:2073-85. 1999..We present our clinical experience in the endovascular treatment of patients with symptomatic VBI from severe atherosclerosis or dissection of the vertebral and subclavian arteries that was unresponsive to medical therapy...
- Infrainguinal vein graft stenosis: cutting balloon angioplasty as the first-line treatment of choicePeter A Schneider
Division of Vascular Therapy, Hawaii Permanente Medical Group, Honolulu, Hawaii 96819, USA
J Vasc Surg 47:960-6; discussion 966. 2008..This study compares three options as first choice for the revision of failing infrainguinal vein grafts: cutting balloon angioplasty (CBA), standard percutaneous transluminal balloon angioplasty (PTA), and open surgical revision (OS).
- Cutting balloon angioplasty for resistant venous stenoses of dialysis access: immediate and patency resultsChih Cheng Wu
Department of Medicine, Hsinchu General Hospital and School of Medicine, Yang Ming University, Taipei, Taiwan
Catheter Cardiovasc Interv 71:250-4. 2008To evaluate the technical success, safety and patency of cutting balloon angioplasty for the treatment of resistant dialysis access stenoses.
- Inhibition of neointimal hyperplasia after balloon injury by cis-element 'decoy' of early growth response gene-1 in hypercholesterolemic rabbitsK Ohtani
Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan
Gene Ther 11:126-32. 2004..The Egr-1 pathway has an essential role in the pathogenesis of neointimal hyperplasia after balloon injury in hypercholesterolemic rabbits. This decoy strategy is a potential practical form of therapy for human restenosis...
- [Balloon angioplasty for native aortic coarctation in children younger than 12 months: immediate and medium-term results]José Rafael Parra-Bravo
Hospital de Pediatria, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Servicio de Cardiología y Hemodinámica Pediátrica, Mexico
Arch Cardiol Mex 77:217-25. 2007The use of the balloon angioplasty (BA) in the treatment of patients with native aortic coarctation during childhood, particularly during the first 12 months of age, is controversial...
- Balloon angioplasty in chronic critical limb ischemia: factors affecting clinical and angiographic outcomeHannes Balmer
Division of Angiology, Swiss Cardiovascular Center, University Hospital, Bern, Switzerland
J Endovasc Ther 9:403-10. 2002To assess factors that affect clinical and angiographic outcome in chronic critical limb ischemia (CLI) 12 months after primary, technically successful balloon angioplasty (BA) in infrainguinal arteries.
- The benefits of carotid endarterectomy in the octogenarian: a challenge to the results of carotid angioplasty and stentingCaron B Rockman
Division of Vascular Surgery, New York University Medical Center, New York, NY 10016, USA
Ann Vasc Surg 17:9-14. 2003..The reasons for the poor outcomes of CAS in the octogenarian are unclear. The results of CAS in the older patient population are worrisome, and this "less invasive" technique may prove to be an inferior alternative in this patient group...
- The outback catheter: a new device for true lumen re-entry after dissection during recanalization of arterial occlusionsKlaus A Hausegger
Department of Radiology, University Hospital Graz, Auenbruggerplatz 9, 8036 Graz, Austria
Cardiovasc Intervent Radiol 27:26-30. 2004....
- Comparison of cutting balloon versus high-pressure balloon angioplasty for resistant venous stenoses of native hemodialysis fistulasChih Cheng Wu
Department of Medicine, Hsinchu General Hospital, No 25, Ln 442, Sec 1, Jingguo Rd, Hsinchu City 300, Taiwan
J Vasc Interv Radiol 19:877-83. 2008To compare the technical success, safety, and patency of cutting balloon angioplasty versus high-pressure balloon angioplasty in the treatment of resistant native hemodialysis fistula stenoses.
- Subintimal placement of covered stent versus subintimal balloon angioplasty in the treatment of long-segment superficial femoral artery occlusionPanagiotis Kougias
Division of Vascular Surgery and Endovascular Therapy, Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston VAMC, Houston TX 77030, USA
Am J Surg 198:645-9. 2009..The relative effectiveness of subintimal placement of a covered stent (CS) versus balloon-only subintimal angioplasty (SIA) remains uncertain...
- Arterial remodeling after balloon angioplasty or stenting in an atherosclerotic experimental modelM J Post
Department of Cardiology, Utrecht University Hospital, and the Interuniversity Cardiology Institute of the Netherlands
Circulation 96:996-1003. 1997Recent studies have indicated that coronary restenosis after balloon angioplasty is the sum of geometric remodeling and neointimal formation...
- Ultra-high-pressure balloon angioplasty for treatment of resistant stenoses within or adjacent to previously implanted pulmonary arterial stentsJessica Maglione
Department of Cardiology, Children s Hospital, Boston, Mass 02115, USA
Circ Cardiovasc Interv 2:52-8. 2009..Angioplasty with ultra-high-pressure (UHP) balloons may facilitate successful treatment of stent-associated PA stenoses that are resistant to high-pressure dilation...
- Cutting balloon angioplasty of bilateral renal artery stenosis due to Takayasu arteritis in a 5-year-old child with midterm follow-upBurcak Gumus
Department of Radiology, Baskent University Hospital, Oymaci Sok No 7, Altunizade, Uskudar, Istanbul, Turkey
Cardiovasc Intervent Radiol 33:394-7. 2010The aim of this report is to demonstrate the successful endovascular treatment of bilateral renal artery stenosis due to Takayasu arteritis by cutting balloon angioplasty in a 5-year-old child with mid-term follow-up.
- Rapid decline in renal function reflects reversibility and predicts the outcome after angioplasty in renal artery stenosisSalomé Muray
Service of Nephrology and Department of Internal Medicine, Hospital Universitari Arnau de Vilanova, Lleida, Spain
Am J Kidney Dis 39:60-6. 2002..46; P = 0.000). Rapidly progressive renal failure is associated with a favorable response on renal failure progression after PTRA in patients with vascular nephropathy and renal artery stenosis...
- Stent graft versus balloon angioplasty for failing dialysis-access graftsZiv J Haskal
Division of Vascular and Interventional Radiology, University of Maryland Medical Center, 22 S Greene St, GK214, Baltimore, MD 21201, USA
N Engl J Med 362:494-503. 2010..b>Balloon angioplasty, the first-line therapy, has a tendency to lead to subsequent recoil and restenosis; however, no other ..
- Decorin inhibition of PDGF-stimulated vascular smooth muscle cell function: potential mechanism for inhibition of intimal hyperplasia after balloon angioplastyNafiseh Nili
Roy and Ann Foss Interventional Cardiology Research Program, Terrence Donnelly Heart Centre, St Michael s Hospital, University of Toronto, 30 Bond Street, Toronto, Ontario, Canada M5B 1W8
Am J Pathol 163:869-78. 2003..Decorin overexpression reduces intimal hyperplasia and collagen content after arterial injury. Decorin may be an effective therapy for the prevention of intimal hyperplasia after balloon angioplasty.
- Cyclooxygenase isozyme expression and intimal hyperplasia in a rat model of balloon angioplastyElizabeth Connolly
Department of Clinical Pharmacology and Surgery, and Institute of Biopharmaceutical Sciences, Royal College of Surgeons in Ireland, Dublin, Ireland
J Pharmacol Exp Ther 300:393-8. 2002..Rats undergoing balloon angioplasty of the carotid artery were randomized to receive a selective COX-2 inhibitor (SC-236), a selective COX-1 ..
- Stenting vs. balloon angioplasty for discrete unoperated coarctation of the aorta in adolescents and adultsCarlos A C Pedra
Instituto Dante Pazzanese de Cardiologia, Sao Paulo, Brazil
Catheter Cardiovasc Interv 64:495-506. 2005More information is needed to clarify whether stenting is superior to balloon angioplasty (BA) for unoperated coarctation of the aorta (CoA)...
- Duplex-assisted internal carotid artery balloon angioplasty and stent placementEnrico Ascher
Maimonides Medical Center, Division of Vascular Surgery, Brooklyn, New York 11219, USA
Perspect Vasc Surg Endovasc Ther 19:41-7. 2007Carotid artery balloon angioplasty and stenting (CBAS) is gaining popularity as an adequate alternative to carotid endarterectomy (CEA) in selected patients...
- Adenovirus-mediated gene transfer of superoxide dismutase and catalase decreases restenosis after balloon angioplastyEric Durand
European Georges Pompidou Hospital, AP HP, INSERM E00 16, Faculté de Médecine Paris V, Universite Rene Descartes, 20 rue Leblanc, FR 75340 Paris Cedex 07, France
J Vasc Res 42:255-65. 2005..We therefore evaluated the effect of adenovirus-mediated gene transfer (Ad) of superoxide dismutase (SOD) and catalase (CAT) on ROS production and restenosis after balloon angioplasty.
- Follow-up results of Cutting Balloon angioplasty used to relieve stenoses in small pulmonary arteriesLisa Bergersen
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, Massachusetts 02115, USA
Cardiol Young 15:605-10. 2005..We sought to determine if the acute gains in pulmonary arterial diameter achieved by using Cutting Balloons to dilate stenoses in small arteries are maintained at follow-up...
- SMART stent for salvage of hemodialysis access graftsPatrick Michael Vogel
Sutter Institute for Medical Research, Sutter Hospital, Sacramento, California, USA
J Vasc Interv Radiol 15:1051-60. 2004..To evaluate the SMART stent for treating angioplasty-resistant hemodialysis access venous stenoses...
- Balloon angioplasty for Blalock-Taussig shunt failure in the early postoperative periodMargaret Macmillan
Division of Pediatric Cardiology, Department of Pediatrics, University of Washington Children s Hospital and Regional Medical Center, Seattle, Washington 98105, USA
Catheter Cardiovasc Interv 66:585-9. 2005..Percutaneous balloon angioplasty (BA) of a stenotic modified Blalock-Taussig shunt (mBTS) has been successfully used in the setting of ..
- Peripheral angioplasty as the first-choice revascularization procedure in diabetic patients with critical limb ischemia: prospective study of 993 consecutive patients hospitalized and followed between 1999 and 2003E Faglia
Diabetology Centre, Diabetic Foot Centre, Policlinico Multimedica, 20099 Sesto S Giovanni, Milano, Italy
Eur J Vasc Endovasc Surg 29:620-7. 2005..To evaluate the effectiveness of peripheral angioplasty (PTA) as the first-choice revascularisation procedure in diabetic patients with critical limb ischemia (CLI)...
- Balloon angioplasty for native aortic coarctation in different anatomic variantsI El Sayed Massoud
Department of Pediatric Cardiology, National Heart Institute, Imbaba, Giza, Egypt
Pediatr Cardiol 29:521-9. 2008b>Balloon angioplasty for native coarctation of the aorta in infants and children is gaining acceptance as an alternative to surgery in discrete membranous obstruction...
- Balloon angioplasty is preferred to surgery for aortic coarctationDerek Wong
Division of Cardiology, Department of Pediatrics, University of Toronto, The Labatt Family Heart Centre, The Hospital for Sick Children, Toronto, Ontario, Canada
Cardiol Young 18:79-88. 2008We sought to use techniques of decision analysis to compare values or preferences for balloon angioplasty versus surgery for treatment of aortic coarctation in children.
- Circumferential pulmonary vein isolation with the cryoballoon technique results from a prospective 3-center studyThomas Neumann
Department of Cardiology, Kerckhoff Heart Center, Bad Nauheim, Germany
J Am Coll Cardiol 52:273-8. 2008..The purpose of this study was to investigate the efficacy safety of the novel cryoballoon device (Arctic Front, Cryocath, Quebec, Canada)...
- Temporal evolution of gene expression in rat carotid artery following balloon angioplastyJian Ming Li
Department of Surgery, Division of Vascular Surgery, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Cell Biochem 101:399-410. 2007..This study highlighted mesenchymal stromal cell cytokines-driven inflammatory extracellular matrix remodeling, as target processes for potential clinical therapeutic intervention...
- Salvaging prosthetic dialysis fistulas with stents: forearm versus upper arm graftsStephen Kolakowski
Section of Vascular Surgery, University of Pennsylvania Hospital, 700 Spruce Street, Philadelphia, PA 19106, USA
J Vasc Surg 38:719-23. 2003..We compared results of angioplasty with those of concomitant stent placement to treat thrombosed forearm hemodialysis grafts with results for upper arm grafts...
- Low-pressure balloon angioplasty with adjuvant pharmacological therapy in patients with acute ischemic stroke caused by intracranial arterial occlusionsRaul G Nogueira
Department of Radiology, Endovascular Neurosurgery Interventional Neuroradiology Section, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
Neuroradiology 50:331-40. 2008..We report our experience using more compliant elastomer balloons for thrombus resistant to intraarterial (IA) pharmacological and mechanical thrombolysis in acute stroke...
- Endovascular treatment of cerebral vasospasm: transluminal balloon angioplasty, intra-arterial papaverine, and intra-arterial nicardipineBrian L Hoh
Endovascular Neurosurgery, Neurosurgical Service, Massachusetts General Hospital, Harvard Medical School, VBK 710, 55 Fruit Street, Boston, MA 02114, USA
Neurosurg Clin N Am 16:501-16, vi. 2005..Vasospasm refractory to medical management can be treated with endovascular therapies, such as transluminal balloon angioplasty or infusion of intra-arterial vasodilating agents...
- Tetradecylthioacetic acid reduces stenosis development after balloon angioplasty injury of rabbit iliac arteriesK K Kuiper
Department of Heart Disease, Haukeland University Hospital, N 5021 Bergen, Norway
Atherosclerosis 158:269-75. 2001..We examined the influence of TTA on the arterial wall response after balloon angioplasty injury in a rabbit iliac model.
- 30 day results from the SPACE trial of stent-protected angioplasty versus carotid endarterectomy in symptomatic patients: a randomised non-inferiority trialP A Ringleb
Lancet 368:1239-47. 2006..Since equivalence or superiority has not been convincingly shown for either treatment, we aimed to compare the two...
- Efficacy of transluminal angioplasty for the management of symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhageR S Polin
Department of Neurosurgery, Louisiana State University Medical Center, Shreveport 71130, USA
J Neurosurg 92:284-90. 2000..In this study the authors assess the efficacy of the aforementioned procedure...
- Essential role of monocyte chemoattractant protein-1 in development of restenotic changes (neointimal hyperplasia and constrictive remodeling) after balloon angioplasty in hypercholesterolemic rabbitsEmiko Mori
Department of Surgery and Science, Kyushu University School of Medical Sciences, Fukuoka, Japan
Circulation 105:2905-10. 2002..Intramuscular transfection of the mutant MCP-1 gene suppressed monocyte infiltration/activation in the injured arterial wall and thus attenuated the development of neointimal hyperplasia and negative remodeling...
- Angioplasty or bypass for superficial femoral artery disease? A randomised controlled trialE S van der Zaag
Department of Surgery, Academic Medical Centre Amsterdam, Maastricht, The Netherlands
Eur J Vasc Endovasc Surg 28:132-7. 2004..To evaluate whether angioplasty or above-knee bypass is the best treatment for symptomatic superficial femoral artery occlusive lesions, we performed a multicentre randomised trial...
- Long-term (up to 20 years) results of percutaneous balloon angioplasty of recurrent aortic coarctation without use of stentsOleg Reich
Kardiocentrum and Cardiovascular Research Centre, University Hospital Motol, Vuvalu 84, Prague 150 18, Czech Republic
Eur Heart J 29:2042-8. 2008To assess the efficacy, safety, and long-term results of the balloon angioplasty of recoarctation.
- A role for urotensin II in restenosis following balloon angioplasty: use of a selective UT receptor blockerEwa Rakowski
Division of Cardiology, Suite L3 109, The Montreal General Hospital, McGill University Health Center, 1650 Cedar Avenue, Montreal, Quebec, Canada H3G 1A4
J Mol Cell Cardiol 39:785-91. 2005..study examined the expression of UII mRNA and immunoreactivity in rat carotid arteries before and after balloon angioplasty. In addition, the effect of UT receptor blockade was assessed in this model using a selective non-peptidic ..
- High resolution magnetic resonance imaging of atherosclerosis and the response to balloon angioplastyR A Coulden
Department of Radiology, Papworth NHS Trust, Papworth Hospital, Cambridge CB3 8RE, UK
Heart 83:188-91. 2000To explore the use of high resolution magnetic resonance imaging (MRI) of the popliteal artery in defining atheroscelerotic lesions and to monitor the remodelling response to balloon angioplasty.
- Interventional catheterization management of perioperative peripheral pulmonary stenosis: balloon angioplasty or endovascular stentingAna Maria Rosales
Department of Cardiology, Children s Hospital, Boston, Massachusetts 02115, USA
Catheter Cardiovasc Interv 56:272-7. 2002..Stent placement increases vessel diameter substantially more than BD alone. Stents reduce the acute complication rate and avoid early reoperation in this patient group...
- Differential expression of matrix metalloproteinases after stent implantation and balloon angioplasty in the hypercholesterolemic rabbitL J Feldman
U460 INSERM, Service d anatomo pathologie, CHU Bichat, Paris, France
Circulation 103:3117-22. 2001..Matrix metalloproteinases (MMPs) play a key role in intimal growth after balloon angioplasty (BA). Little is known, however, about MMP expression after stent implantation (ST)...
- Cutting balloon versus conventional balloon angioplasty for the treatment of in-stent restenosis: results of the restenosis cutting balloon evaluation trial (RESCUT)Remo Albiero
Columbus Hospital, Milan, Italy
J Am Coll Cardiol 43:943-9. 2004The aim of this trial was to compare cutting balloon angioplasty (CBA) with conventional balloon angioplasty (i.e...
- Effects of Insulin on VSM MigrationAndrew Kahn; Fiscal Year: 2004DESCRIPTION (Verbatim from the application): Atherosclerosis and arterial restenosis following balloon angioplasty is enhanced in insulin resistant conditions, where migration of vascular smooth muscle cells (VSMCs) from the media to ..
- Improved Adventitial Sirolimus Therapy for Peripheral Artery RestenosisKIRK SEWARD; Fiscal Year: 2010..Unfortunately, only one-third of patients have a patent artery one year after balloon angioplasty of the femoral artery ...
- EFFECT OF LIPIDS ON VASCULAR GRAFT HEALINGLinda M Graham; Fiscal Year: 2013..RELEVANCE: The long-term goal of our research is improve the healing of bypass grafts or arteries after balloon angioplasty and stenting...
- EPICARDIAL ADIPOSE TISSUE, OBESITY AND INFLAMMATION IN ATHEROSCLEROSISDevendra K Agrawal; Fiscal Year: 2013..Hypercholesterolemic swine on high fructose diet will undergo balloon angioplasty and stenting...
- ECM compliance and cell cycle controlRICHARD ASSOIAN; Fiscal Year: 2012..are critical aspects of both atherosclerosis and restenosis (smooth muscle cell proliferation after balloon angioplasty)...
- The role of the orphan receptor tyrosine kinase Ros1 in vascular diseaseZIAD ANWAR ALI; Fiscal Year: 2011..the development of atherosclerosis and the response to vascular injury such as venous bypass grafting and balloon angioplasty and stenting...
- 3D Single Fiber Endoscope for Minimally Invasive SurgeriesJason Geng; Fiscal Year: 2013..based surgeries), eye surgeries and drug placement on optic nerves, interventional cardiology procedures of balloon angioplasty and stenting;arthroscopic procedures, including knee, shoulder, small joint and hips;and laparoscopic ..
- VITAMIN D AND IMMUNOMODULATION IN CORONARY ARTERY DISEASEDevendra K Agrawal; Fiscal Year: 2013..The incidence of angiographic restenoses following balloon angioplasty/stent implantation correlates well with the incidence of vitamin D deficiency/insufficiency...
- Thrombospondin-1, VSMC Migration and Intimal Hyperplasia - a role for statinsVivian Gahtan; Fiscal Year: 2013DESCRIPTION (provided by applicant): Peripheral arterial disease and restenosis after balloon angioplasty to treat arterial blockages is a significant cause of disability and death in the veteran population...
- Novel Approaches in Treatment of Vascular Injury Following Balloon AngioplastyYEVGENIYA EMRE KOSHMAN; Fiscal Year: 2013..goal of this research project is to develop novel approaches in treatment of vascular injury following balloon angioplasty. The overall hypothesis of my NRSA application is that upregulation of FRNK, a naturally occurring ..
- The role of the orphan receptor tyrosine kinase Ros1 in vascular diseaseZIAD ANWAR ALI; Fiscal Year: 2013..the development of atherosclerosis and the response to vascular injury such as venous bypass grafting and balloon angioplasty and stenting...
- Assembly and Trafficking of IK1 and SK3 in EndotheliaDaniel C Devor; Fiscal Year: 2012..Also, the expression of these channels in endothelia has been shown to be compromised following balloon angioplasty. Finally, these channels are known to be critical to EDHF-mediated vasodilation, which is compromised in a ..
- A Luminal Vascular Coating to Prevent Intimal Hyperplasia Following Creation of aKate Stuart; Fiscal Year: 2013..DS-SILY to be successful in preventing platelet adhesion and intimal hyperplasia in a porcine model of balloon angioplasty. Here we will test the ability of DS-SILY to prevent neointimal hyperplasia in a well-characterized porcine ..
- Carbon monoxide mediated inhibition of intimal hyperplasiaEdith Tzeng; Fiscal Year: 2013..A short exposure to inhaled CO dramatically inhibits balloon angioplasty induced IH in animals without any evidence of toxicity...
- Improved Therapeutics for Drug Eluting StentsAlyssa Panitch; Fiscal Year: 2013..by applicant): The number of percutaneous coronary intervention (PCI) procedures, commonly known as balloon angioplasty, has increased by 30% over the past 10 years totaling more than 1.3 million patients in the U.S...
- TNF mRNA stability and restenosisRaj Kishore; Fiscal Year: 2012..PUBLIC HEALTH RELEVANCE: The opening of clogged blood vessels by balloon angioplasty relieves the symptoms of heart disease, however, the procedure is compromised by re-narrowing of the ..
- A Revolutionary Therapy for Atherosclerosis: Liquid Cast Arterial StentsGuillermo A Ameer; Fiscal Year: 2010..stent will have superior patency rates compared to conventional bare metal stents following percutaneous balloon angioplasty. The specific aims of this 2-year proposal are to: 1) optimize NO release from the diazeniumdiolated PDC;2) ..
- GENE THERAPY WITH SOCS-3 IN INTIMAL HYPERPLASIA AND IN-STENT RESTENOSISDevendra K Agrawal; Fiscal Year: 2013..Aim 1: Our hypothesis predicts that the introduction of SOCS3 transgene at the site of balloon angioplasty in atherosclerotic coronary artery will prevent the development of intimal hyperplasia...
- PHYSIOLOGY OF FLUOROCARBON OXYGEN TRANSPORTLELAND CLARK; Fiscal Year: 1992..Control of tissue oxygenation by fluorocarbons may be used in cardiac balloon angioplasty, cardioplegia and NMR imaging...
- MESENCHYMAL STEM CELLS IN THE PREVENTION OF THROMBOSIS AND NEOINTIMAL HYPERPLASIADevendra K Agrawal; Fiscal Year: 2013..Aim 1: Test the hypothesis that overexpression of PTEN transgene with MSCs at the site of balloon angioplasty in atherosclerotic coronary artery prevents thrombosis and the development of neointimal hyperplasia...
- Novel Vehicles for Targeted Cardiovascular RepairSamuel I Stupp; Fiscal Year: 2013..Current therapeutic modalities for the treatment of severe coronary and peripheral artery disease include balloon angioplasty and stenting, endarterectomy, or bypass grafting...
- Suppression of VSMC Activation and Mechanisms of Vascular Protection by IL-19Michael V Autieri; Fiscal Year: 2012..IL-19 adenoviral gene transfer significantly reduces neointimal formation and VSMC proliferation in balloon angioplasty-injured rat carotid arteries...
- Improved Adventitial Rapamycin Therapy for Peripheral Artery RestenosisKIRK SEWARD; Fiscal Year: 2013..Unfortunately, only one-third of patients have a patent artery one year after balloon angioplasty of the femoral artery ...
- Appropriateness Criteria for Coronary Revascularization: Measurement and ValidityPAUL SHEUNG YAN CHAN; Fiscal Year: 2013..PROJECT NARRATIVE: Recently, criteria which assess whether a balloon angioplasty or heart stent procedure is appropriate for a patient have been published by cardiology professional ..
- CaMKII regulates key mechanisms of vascular response to injury in vivoISABELLA MARIA GRUMBACH; Fiscal Year: 2013..Neointima formation and remodeling occur in vein graft failure after coronary artery bypass surgery, after balloon angioplasty and surgical endarterectomy and have a significant impact in terms of morbidity and health care cost...
- Comparative Effectiveness of Coronary StentsEdward Hannan; Fiscal Year: 2013..Initially, these procedures were performed using only balloon angioplasty, then primarily with bare-metal stents (BMS), and now drug-eluting stents (DES) are by far the most common ..
- Molecular Targeted, Focused, Ultrasound-Based Delivery of Antiproliferative DrugsJohn A Hossack; Fiscal Year: 2012DESCRIPTION (provided by applicant): Revascularization of a diseased blood vessel is currently performed by balloon angioplasty and deployment of a metal stent...
- Using Clinically-Enhanced Claims Data to Guide Selection of Coronary ProceduresHAROLD KILBURN; Fiscal Year: 2010..medical treatment decisions, patient outcomes after treatment of heart artery blockage by surgery and by balloon angioplasty will be compared using clinically-enhanced data and using complete clinical data from difficult-to-maintain ..
- Catheter-mounted Device for Measuring Intravascular Flow and PressureDavid Vilkomerson; Fiscal Year: 2012..proposed Phase II, the pressure and flow sensors will be integrated onto procedural catheters, such as for balloon angioplasty or stent placement, and the safety and usefulness of the device in guiding procedures demonstrated in ..
- MPO and NO signaling in neointima formationChunxiang Zhang; Fiscal Year: 2010..The current proposal will identify a novel mediator, leukocyte-derived MPO, in neointima formation and its molecular mechanism(s). Blocking the MPO pathway might be a new therapeutic approach to restenosis after balloon angioplasty.
- Combined Intravascular Ultrasound and Photoacoustic Imaging of AtherosclerosisStanislav Y Emelianov; Fiscal Year: 2010..at the shoulders of the fibrous cap, and c) guide coronary artery interventions including percutaneous balloon angioplasty, endovascular stenting, ablation/vaporization and brachytherapy...
- PLATELETS, PLATELET AGGREGATES & PLASMINOGEN ACTIVATIONJoseph Loscalzo; Fiscal Year: 1991..and stroke, and is a crucial event in reocclusion following thrombolytic therapy and transluminal balloon angioplasty. We have demonstrated in preliminary work that tissue plasminogen activator added to platelets induced to ..
- MECHANISMS OF MYOCARDIAL REPERFUSION INJURYMERVYN FORMAN; Fiscal Year: 1991..The introduction of more effective and safer thrombolytic agents and percutaneous balloon angioplasty in evolving mycocardial infarction has resulted in increasing numbers of patients undergoing successful ..
- IMAGING INTIMAL HYPERPLASIA, MYOCYTE HYPOXIA, NECROSISLynne Johnson; Fiscal Year: 2000..Catheter techniques to reduce luminal narrowing include percutaneous balloon angioplasty and coronary stenting...
- SELECTINS ROLE IN VASCULAR INJURY IN GENE-TARGETEDIan Sarembock; Fiscal Year: 2004..Restenosis after percutaneous interventions remain a major challenge, occurring in 20-40 percent after balloon angioplasty or stents...
- LOCAL THERAPY TO LIMIT VASCULAR GRAFT HYPERPLASIAStephen Massia; Fiscal Year: 2002..This drug class has also been shown to effectively limit clinical restenosis following coronary arterial balloon angioplasty. In the proposed study, it is hypothesized that under optimal conditions, locally delivered alphaV integrin ..
- SEQUESTER HYALURONAN--LIMIT CHRONIC ALLOGRAFT REJECTIONRASHMIN SAVANI; Fiscal Year: 1999..the vascular lesions of CR and the neointimal formation observed in atherosclerosis and restenosis after balloon angioplasty. In particular, inflammatory cell infiltration, disruption of the internal elastic lamina, proliferation ..
- MICROWAVE PLAQUE WELDING FOLLOWING BALLOON ANGIOPLASTYCAREY RAPPAPORT; Fiscal Year: 1990..microwave technology as well as a drastically new approach to improve the powerful treatment procedure of balloon angioplasty. Extensive literature searches have indicated that microwave plaque welding has not been previously ..
- ZYNPEPTIDES AS MODULATORS OF RESPONSES TO BIOMATERIALSGregory Kopia; Fiscal Year: 1991..which are placed in atherosclerotic human coronary and iliac arteries to keep them from collapsing after balloon angioplasty. A necessary adjunct to stent implantation is systemic antiplatelet and anticoagulant therapy to prevent ..
- SHEAR STRESS ENHANCEMENT OF SMOOTH MUSCLE CELL MIGRATIONJohn Shyy; Fiscal Year: 2003..Aim 4 is to investigate the roles of Cbl, Rho, and Rac in VSMC migration in rat carotid arteries after balloon angioplasty. Specifically, we will examine the activation of Cbl, Rho and Rac in injured vessels and test the efficacy ..
- MRI-Guided Angioplasty of Renal Artery StenosisReed Omary; Fiscal Year: 2005..rate, complication rate, and procedure time for MRI-guided and x-ray guided percutaneous transluminal balloon angioplasty (PTA) of renal artery stenosis are similar; and 3) Successful MRI-guided PTA of renal artery stenosis ..
- MECHANICAL BASIS FOR OPTIMAL BALLOON ANGIOPLASTYLinda Demer; Fiscal Year: 1993Goal. The long term objective of this project is to improve the safety and efficacy of percutaneous balloon angioplasty by establishing a scientific basis for determining the optimal dilation method based on measurements of the ..
- LASER BALLOON ANGIOPLASTYJames Spears; Fiscal Year: 1990Abrupt reclosure and gradual restenosis greatly limit the safety and efficacy of percutaneous transluminal balloon angioplasty (BA) in the treatment of obstructive coronary atherosclerosis...
- IN VIVO ENDOTHELIAL INJURY AND DEPENDENT VASOMOTIONJames Chesebro; Fiscal Year: 1990..a probe for measuring the timing and degree of endothelial healing just proximal and distal to the site of balloon angioplasty (where there is endothelial damage but no smooth muscle cell necrosis), in the symptom-producing artery ..
- Vascular Remodeling in Transplant ArteriosclerosisChristiane Ferran; Fiscal Year: 2009..In addition, overexpression of A20 in rat carotid artery SMC following balloon angioplasty prevents but also cures neointima formation and promotes healing by increasing re-endothelialization...
- EFFECT OF THROMBIN INHIBITION BY HIRUDIN ON ANGIOPLASTYIan Sarembock; Fiscal Year: 1993..the effectiveness of recombinant hirudin (r-hirudin), a thrombin inhibitor, in limiting restenosis after balloon angioplasty in our rabbit model...
- MOLECULAR BARRIERS TO THROMBOSIS ON TISSUE SURFACESWilliam Wagner; Fiscal Year: 2002..prevent neointimal hyperplasia exacerbated by this acute thrombosis, and prevent restenosis following balloon angioplasty of a stenotic lesion...
- MR-Guided Coronary Balloon AngioplastyErgin Atalar; Fiscal Year: 2004..Conventional interventional procedures, such as balloon angioplasty or intravascular stent placement, are primarily guided by x-ray fluoroscopy with contrast injections ..
- Oxidation and Pharmacologic Activation of IK/SK ChannelsDANIEL DEVOR; Fiscal Year: 2009..The expression of these channels in endothelia has also been shown to be compromised following balloon angioplasty. Finally, these channels are known to be critical to EDHF-mediated vasodilation, which is compromised in a ..
- ARTERIAL BIOLOGIC RESPONSE TO ENDOVASCULAR IRRADIATIONKeith Robinson; Fiscal Year: 2003..findings have prompted several clinical trials of vascular brachytherapy for prevention of restenosis after balloon angioplasty and endovascular stenting; preliminary results available in some studies have documented a reduction in ..
- ESTROGEN FOR PREVENTION OF RESTENOSIS IN OLDER WOMENDouglas Losordo; Fiscal Year: 2000b>Balloon angioplasty has been shown to be superior to medical treatment for the relief of symptoms and ischemia in patients with single vessel coronary artery disease...
- IMAGING SYSTEM FOR LOW ACTIVITY BRACHYTHERAPY SOURCESYU TARNG CHENG; Fiscal Year: 2000More than 20 years after the advent of balloon angioplasty, restenosis remains a major health care cost burden...
- Analysis of a Retinoid-Induced Tumor Suppressor in SMCJOSEPH MIANO; Fiscal Year: 2006..anti-cancer drugs that have been shown to reduce neointimal formation associated with atherosclerosis and balloon angioplasty, apparently by inhibiting smooth muscle cell (SMC) growth and migration...
- Ethanol mediated endothelial injury and dysfunctionRaj Kishore; Fiscal Year: 2007..TNF expressed at the sites of arterial injury following balloon angioplasty suppresses endothelial cell (EC) proliferation and contributes to the development of restenosis...
- CORONARY STENTS WITH ION IMPLANTED RADIOACTIVITYANTHONY ARMINI; Fiscal Year: 2000Catheter-based temporary radiation therapy following balloon angioplasty has been shown in clinical studies to reduce restenosis...
- CAN IVUS MANAGE CORONARY ARTERY INTERVENTIONSMATTHEW O DONNELL; Fiscal Year: 2003..It focuses on the common mechanical interventions of balloon angioplasty (PCTA) and endovascular stenting...
- Cell cycle control of vascular remodelingRICHARD ASSOIAN; Fiscal Year: 2009..Arterial injury, such as that associated with atherosclerosis and balloon angioplasty, impairs the release of these antimitogens and (together with injury-associated exposure to local mitogens ..
- PDE1C REGULATION OF VASCULAR SMOOTH MUSCLE PROLIFERATIONJoseph Beavo; Fiscal Year: 2001..characterized by increased SMC proliferation (atherosclerotic lesions, neonatal pulmonary hypertension, balloon angioplasty) in human or ovine tissue. Conversely, quiescent cells should express little PDE1C...
- TGF-B1 RECEPTORS IN RESTENOSIS AND AGINGTimothy McCaffrey; Fiscal Year: 2000..Because TGF-beta1 is overexpressed in fibroproliferative vascular lesions, such as restenosis after balloon angioplasty, this selective loss of growth inhibitory function allows the SMC to grow in a slow, uncontrolled fashion, ..
- Adhesion Signaling in Vascular Growth and DevelopmentJoan Taylor; Fiscal Year: 2006..of several prominent cardiovascular disease states such as atherosclerosis, restenosis following balloon angioplasty, and hypertension...
- HUMAN ARTERIAL VASOREACTIVITY FOLLOWING INJURYTim Fischell; Fiscal Year: 1991..The morphologic sequelae of balloon angioplasty (BA) have been well described and include plaque fracture, endothelial denudation with platelet deposition, ..
- Stented Artery Wall Stresses and RetenosisJames Moore; Fiscal Year: 2006unreadable] DESCRIPTION (provided by applicant): Balloon angioplasty and stenting are techniques for treating atherosclerosis that are increasing in use...