tissue and organ harvesting

Summary

Summary: The procedure of removing TISSUES, organs, or specimens from DONORS for reuse, such as TRANSPLANTATION.

Top Publications

  1. ncbi Adipose tissue-derived mesenchymal stem cell yield and growth characteristics are affected by the tissue-harvesting procedure
    M J Oedayrajsingh-Varma
    Department of Plastic Reconstructive and Hand Surgery, VU University Medical Center, Amsterdam, The Netherlands
    Cytotherapy 8:166-77. 2006
  2. ncbi Organ yield from deceased donors: initial experience of an organ procurement unit in Iran
    Seyed Mohammad Kazemeyni
    Department of Urology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Arch Iran Med 12:170-2. 2009
  3. ncbi Donation after circulatory death: burying the dead donor rule
    David Rodríguez-Arias
    Universidad del Pais Vasco EHU
    Am J Bioeth 11:36-43. 2011
  4. ncbi Intraoperative catecholamine release in brain-dead organ donors is not suppressed by administration of fentanyl
    R D Fitzgerald
    Ludwig Boltzmann Institute for Economics of Medicine in Anaesthesia and Intensive Care, Vienna, Austria
    Eur J Anaesthesiol 20:952-6. 2003
  5. ncbi Endoscopic greater saphenous vein harvesting reduces the morbidity of coronary artery bypass surgery
    Chance D Felisky
    Department of Surgery, Section of Cardiothoracic Surgery, Virginia Mason Medical Center, 1201 Terry Ave, Seattle, WA 98101, USA
    Am J Surg 183:576-9. 2002
  6. ncbi Introducing hand-assisted retroperitoneoscopic live donor nephrectomy: learning curves and development based on 413 consecutive cases in four centers
    Jonas Wadstrom
    Department of Surgery, Uppsala University Hospital, Uppsala, Sweden
    Transplantation 91:462-9. 2011
  7. ncbi A prospective randomized trial of endoscopic versus conventional harvesting of the saphenous vein in coronary artery bypass surgery
    Bob Kiaii
    Department of Surgery, University of Western Ontario, London, Ontario, Canada
    J Thorac Cardiovasc Surg 123:204-12. 2002
  8. ncbi Repair of radial free flap donor site by full-thickness skin graft from inner arm
    C M E Avery
    Department of Maxillofacial Surgery, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK
    Br J Oral Maxillofac Surg 43:161-5. 2005
  9. ncbi Organ donation and time to procurement: late is not too late
    Kenji Inaba
    Division of Trauma and Surgical Critical Care, University of Southern California, 1200 North State Street, Room CL5100, Los Angeles, CA 90033 4525, USA
    J Trauma 68:1362-6. 2010
  10. ncbi Nonsimultaneous administration of pancreas dissociation enzymes during islet isolation
    Tatsuya Kin
    Clinical Islet Transplant Program, University of Alberta and Alberta Health Services, Edmonton, Alberta, Canada
    Transplantation 87:1700-5. 2009

Detail Information

Publications250 found, 100 shown here

  1. ncbi Adipose tissue-derived mesenchymal stem cell yield and growth characteristics are affected by the tissue-harvesting procedure
    M J Oedayrajsingh-Varma
    Department of Plastic Reconstructive and Hand Surgery, VU University Medical Center, Amsterdam, The Netherlands
    Cytotherapy 8:166-77. 2006
    ..We studied whether the yield and growth characteristics of ASC were affected by the type of surgical procedure used for adipose tissue harvesting, i.e. resection, tumescent liposuction and ultrasound-assisted liposuction...
  2. ncbi Organ yield from deceased donors: initial experience of an organ procurement unit in Iran
    Seyed Mohammad Kazemeyni
    Department of Urology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Arch Iran Med 12:170-2. 2009
    ..This study showed that organ procurement units can improve organ yield and both experience and donor characteristics influence on the number of harvested organs...
  3. ncbi Donation after circulatory death: burying the dead donor rule
    David Rodríguez-Arias
    Universidad del Pais Vasco EHU
    Am J Bioeth 11:36-43. 2011
    ....
  4. ncbi Intraoperative catecholamine release in brain-dead organ donors is not suppressed by administration of fentanyl
    R D Fitzgerald
    Ludwig Boltzmann Institute for Economics of Medicine in Anaesthesia and Intensive Care, Vienna, Austria
    Eur J Anaesthesiol 20:952-6. 2003
    ..Our hypothesis was that inhibition of pain by fentanyl would inhibit such catecholamine release...
  5. ncbi Endoscopic greater saphenous vein harvesting reduces the morbidity of coronary artery bypass surgery
    Chance D Felisky
    Department of Surgery, Section of Cardiothoracic Surgery, Virginia Mason Medical Center, 1201 Terry Ave, Seattle, WA 98101, USA
    Am J Surg 183:576-9. 2002
    ..In 1997, all GSV harvesting was performed by open technique. During a transition period in 1998 and 1999 we used several different endoscopic techniques. By the beginning of 2000, our technique of EVH was standardized and used routinely...
  6. ncbi Introducing hand-assisted retroperitoneoscopic live donor nephrectomy: learning curves and development based on 413 consecutive cases in four centers
    Jonas Wadstrom
    Department of Surgery, Uppsala University Hospital, Uppsala, Sweden
    Transplantation 91:462-9. 2011
    ..This study reports on our four-center experience, development, and learning curves from the first 413 LDNs using a hand-assisted retroperitoneoscopic (HARS) technique...
  7. ncbi A prospective randomized trial of endoscopic versus conventional harvesting of the saphenous vein in coronary artery bypass surgery
    Bob Kiaii
    Department of Surgery, University of Western Ontario, London, Ontario, Canada
    J Thorac Cardiovasc Surg 123:204-12. 2002
    ....
  8. ncbi Repair of radial free flap donor site by full-thickness skin graft from inner arm
    C M E Avery
    Department of Maxillofacial Surgery, University Hospitals of Leicester NHS Trust, Leicester LE1 5WW, UK
    Br J Oral Maxillofac Surg 43:161-5. 2005
    ..Both patients and surgeons rated the aesthetic outcome as good. The advantages included; single operation site; simple execution; thin hairless graft, good colour match and an inconspicuous scar causing minimal morbidity...
  9. ncbi Organ donation and time to procurement: late is not too late
    Kenji Inaba
    Division of Trauma and Surgical Critical Care, University of Southern California, 1200 North State Street, Room CL5100, Los Angeles, CA 90033 4525, USA
    J Trauma 68:1362-6. 2010
    ..No consensus exists as to the maximal period of time allowable after brain death (BD) before organ procurement rates begin to deteriorate. The aim of this study was to examine organ procurement rates as a function of time after BD...
  10. ncbi Nonsimultaneous administration of pancreas dissociation enzymes during islet isolation
    Tatsuya Kin
    Clinical Islet Transplant Program, University of Alberta and Alberta Health Services, Edmonton, Alberta, Canada
    Transplantation 87:1700-5. 2009
    ..However, this conversion significantly affected the field in transplant activity. Here, we report our successful conversion from Liberase to Serva collagenase with the use of a modified digestion protocol...
  11. ncbi A matter of respect: a defense of the dead donor rule and of a "whole-brain" criterion for determination of death
    George Khushf
    University of South Carolina, Columbia, SC 29208, USA
    J Med Philos 35:330-64. 2010
    ....
  12. ncbi Optimization of neutral protease to collagenase activity ratio for islet of Langerhans isolation
    P Bucher
    Cell Isolation and Transplantation Center, Department of Surgery, Geneva University Hospitals, Geneva, Switzerland
    Transplant Proc 36:1145-6. 2004
    ..The optimal neutral protease to collagenase activity ratio has not been determined for islet isolation. We evaluated a new highly purified collagenase that can be blended with predetermined amounts of neutral protease (NP)...
  13. ncbi Death revisited: rethinking death and the dead donor rule
    Ana Smith Iltis
    Saint Louis University, 221 North Grand Blvd, St Louis, MO 63103, USA
    J Med Philos 35:223-41. 2010
    ..We explore the ongoing debate over definitions of death, particularly over brain death or death determined using neurological criteria, and the relationship between definitions of death and organ transplantation...
  14. ncbi The detrimental effect of poor early graft function after laparoscopic live donor nephrectomy on graft outcomes
    J M Nogueira
    Division of Nephrology, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA
    Am J Transplant 9:337-47. 2009
    ..001). Risk factors for poor DGF included advanced donor age, high recipient BMI, sirolimus use and prolonged warm ischemia time. In conclusion, poor EGF following lapNx has a deleterious effect on long-term graft function and survival...
  15. ncbi Heart transplantation in iran; a comprehensive single-center review of 15-year performance
    Mohammad Hossein Mandegar
    Department of Cardiac Surgery, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
    Arch Iran Med 12:111-5. 2009
    ..This is a comprehensive review of our 15-year practice registry to make a scheme of our record and achievements...
  16. pmc A new enzyme mixture to increase the yield and transplant rate of autologous and allogeneic human islet products
    A N Balamurugan
    Schulze Diabetes Institute, University of Minnesota, Minneapolis, MN 55455, USA
    Transplantation 93:693-702. 2012
    ..The ECs consisted of purified, intact or truncated class 1 (C1) and class 2 (C2) collagenases from Clostridium histolyticum (Ch), and neutral protease (NP) from Bacillus thermoproteolyticus rokko (thermolysin) or Ch (ChNP)...
  17. ncbi Organ retrieval from brain-dead patients by a single organ procurement center in Iran
    K Najafizadeh
    Lung Transplantation Research Center, National Research Institute of TB and Lung disease, Shaheed Beheshti Medical University, Tehran, Iran
    Transplant Proc 41:2723-5. 2009
    ..In recent years, special focus has been directed toward brain-dead patients in Iran, but it seems that there is limited information regarding the characteristics of cadaveric organ donation in our country...
  18. ncbi Maxillary sinus and ridge augmentations using a surface-derived autogenous bone graft
    Michael Peleg
    Department of Surgery, Division of Oral Maxillofacial Surgery, University of Miami School of Medicine, FL 33136, USA
    J Oral Maxillofac Surg 62:1535-44. 2004
    ..A handheld instrument is described that cuts and collects thin shavings of bone from cortical surfaces...
  19. pmc Experience of islet isolation without neutral protease supplementation
    Tatsuya Kin
    Clinical Islet Laboratory and Clinical Islet Transplant Program, University of Alberta, Edmonton, Alberta, Canada
    Islets 2:278-82. 2010
    ..As a result NP was not added at all for these isolations (no-NP group). In the remaining 84 isolations, NP was added during digestion phase (control group)...
  20. ncbi Radial forearm free flap donor site outcomes comparison by closure methods
    Tang Ho
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, Texas, USA
    Otolaryngol Head Neck Surg 134:309-15. 2006
    ....
  21. ncbi Preparation techniques for the injection of human autologous cartilage: an ex vivo feasibility study
    J Pieter Noordzij
    Department of Otolaryngology Head and Neck Surgery, Boston University Medical Center, 88 East Newton Street, Boston, MA 02118, USA
    Laryngoscope 118:185-8. 2008
    ..To determine the optimum donor site and preparation technique for injecting human autologous cartilage as a potentially permanent implant material for vocal fold medialization...
  22. ncbi Utilization of intensive care units' beds occupied by brain-dead patients
    Mohammed Abdullah Alsultan
    King Saud Bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia
    Saudi J Kidney Dis Transpl 22:444-7. 2011
    ..07). In conclusion, I believe a better utilization of the intensive care units' beds by other than brain-dead patients would not produce great cost savings, but may provide care for more patients with better quality of care...
  23. ncbi Endoscopic vessel harvesting in coronary artery bypass graft surgery
    Christopher W Nickum
    Section of Cardiothoracic Surgery, Cleveland Clinic Florida, Weston, FL, USA
    JAAPA 18:40, 42, 44, 51-3. 2005
  24. ncbi Transplanting hearts after death measured by cardiac criteria: the challenge to the dead donor rule
    Robert M Veatch
    Georgetown University, Washington, DC 20057, USA
    J Med Philos 35:313-29. 2010
    ..The first two strategies are the most ethically justifiable and practical...
  25. pmc Evaluation of endoscopic vein extraction on structural and functional viability of saphenous vein endothelium
    Bader E Hussaini
    Cardiothoracic Surgery Division, Veterans Affairs Boston Healthcare System, Boston, MA, USA
    J Cardiothorac Surg 6:82. 2011
    ....
  26. ncbi A systematic review of the effectiveness of bone collectors
    Filippo Graziani
    Department of Surgery, Section of Oral Surgery, University of Pisa, Italy
    Int J Oral Maxillofac Implants 22:729-35. 2007
    ..The objective of this study was to systematically review the use of bone collectors in implant dentistry, focusing on the quantity, quality, and bacterial contamination of the bone collected...
  27. ncbi Functional improvement between brain death declaration and organ harvesting
    I Grigoras
    University of Medicine and Pharmacy, School of Medicine, Iasi, Romania
    Transplant Proc 42:147-9. 2010
    ..This study sought to investigate the evolution of the functional status of brain death (BD) patients during the period between declaration and organ harvesting (BD duration)...
  28. ncbi Use of irradiated bone graft for impaction grafting in acetabular revision surgery: a review of fifty consecutive cases
    Sanchit Mehendale
    Department of Orthopaedic Surgery, University of Bristol, UK
    Hip Int 19:114-9. 2009
    ..The results suggested that acetabular impaction bone grafting using irradiated bone graft is comparable to fresh frozen allograft. The low percentage of remodelling remains a concern and warrants further studies...
  29. ncbi Dynamic evaluation of contact pressure and the effects of graft harvest with subsequent lateral release at osteochondral donor sites in the knee
    Joseph H Guettler
    Sports Medicine Service, William Beaumont Hospital, Royal Oak, Michigan, USA
    Arthroscopy 21:715-20. 2005
    ....
  30. ncbi A novel bone scraper for intraoral harvesting: a device for filling small bone defects
    Davide Zaffe
    Department of Anatomy and Histology, Section of Human Anatomy, University of Modena and Reggio Emilia, Modena, Italy
    Clin Oral Implants Res 18:525-33. 2007
    ..To evaluate histologically the morphology and characteristics of bone chips harvested intraorally by Safescraper, a specially designed cortical bone collector...
  31. ncbi Endoscopic vein harvesting in cardiac surgery
    P Brian Seabolt
    Methodist Hospital, Houston, Texas 77030, USA
    Curr Opin Cardiol 18:444-6. 2003
    ..Wound dehiscence, recurrent cellulitis, hematomas, neuropathies, and impaired mobility are often experienced by patients who have undergone open harvest techniques...
  32. ncbi How I manage the adult potential organ donor: donation after neurological death (part 1)
    Jennifer A Frontera
    Mount Sinai School of Medicine, New York, NY, USA
    Neurocrit Care 12:103-10. 2010
    ..Since each potential donor could save seven lives or more, nihilism in the care of such patients can have far reaching ramifications. This article describes intensive care management practices that can optimize organ donation...
  33. ncbi Wound-healing disturbances after vein harvesting for CABG: a randomized trial to compare the minimally invasive direct vision and traditional approaches
    V Düsterhöft
    Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum Berlin, Germany
    Ann Thorac Surg 72:2038-43. 2001
    ..The aim of this study was to compare the results of our minimally invasive technique with the traditional method...
  34. ncbi Minimally invasive saphenous vein harvesting: is there an improvement of the results with the endoscopic approach?
    F Isgro
    Heartcenter Ludwigshafen, Clinic for Cardiac Surgery, Germany
    Eur J Cardiothorac Surg 16:S58-60. 1999
    ..Therefore the primary goal of this investigation was to prove the safety and practicability of this new less invasive technique for saphenous vein harvesting and the effect on complications and morbidity...
  35. ncbi Endoscopic versus open saphenous vein harvest: a comparison of postoperative wound complications
    Jerene M Bitondo
    Division of Cardiac Surgery, Massachusetts General Hospital, Boston 02114, USA
    Ann Thorac Surg 73:523-8. 2002
    ..Recent reports suggest that techniques of endoscopic vein harvest may result in decreased wound complications. A prospective, nonrandomized study was developed to compare outcomes of open versus endoscopic vein harvest procedures...
  36. ncbi Laparoscopic donor nephrectomy gene expression profiling reveals upregulation of stress and ischemia associated genes compared to control kidneys
    Sunil M Kurian
    Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA, USA
    Transplantation 80:1067-71. 2005
    ..These data demonstrate an altered renal transcriptome induced by several hours of CO2 pneumoperitoneum and laparoscopic surgery characterized by upregulation of ischemia and injury associated genes...
  37. ncbi Postoperative pain and convalescence in living kidney donors-laparoscopic versus open donor nephrectomy: a randomized study
    M H Andersen
    Department of Surgery, Rikshospitalet Radiumhospitalet University, Norway
    Am J Transplant 6:1438-43. 2006
    ....
  38. ncbi Contact pressure at osteochondral donor sites in the patellofemoral joint
    Ralph B Garretson
    Department of Orthopedic Surgery, University of Pennsylvania Hospitals, Philadelphia, PA, USA
    Am J Sports Med 32:967-74. 2004
    ..The lowest contact pressure point is presumed to be the best site to harvest an osteochondral plug and minimize morbidity...
  39. ncbi Comparison of human islet isolation outcomes using a new mammalian tissue-free enzyme versus collagenase NB-1
    Doug O'Gorman
    Department of Transplant Services, Alberta Health Services, Edmonton, AB, Canada
    Transplantation 90:255-9. 2010
    ..We report our experience using the MTF enzyme in clinical islet isolations compared with Serva NB-1 with modified enzyme delivery method...
  40. ncbi Impact of endoscopic versus open saphenous vein harvest technique on late coronary artery bypass grafting patient outcomes in the ROOBY (Randomized On/Off Bypass) Trial
    Marco A Zenati
    Veterans Affairs Boston Healthcare System, West Roxbury, MA 02132, USA
    J Thorac Cardiovasc Surg 141:338-44. 2011
    ..This ROOBY Trial planned subanalysis compared the effects on postbypass patient clinical outcomes and graft patency of endoscopic vein harvesting and open vein harvesting...
  41. ncbi Laparoscopic live donor nephrectomy: a risk factor for delayed function and rejection in pediatric kidney recipients? A UNOS analysis
    Christoph Troppmann
    Department of Surgery, University of California Davis Medical Center, Sacramento, CA, USA
    Am J Transplant 5:175-82. 2005
    ..Future investigations must confirm these findings and identify strategies to optimize procurement and pediatric recipient outcome...
  42. ncbi How to improve the quality of kidneys from non-heart-beating donors: a randomised controlled trial of thrombolysis in non-heart-beating donors
    Muhammad A Gok
    Department of Surgery, The Medical School, University of Newcastle upon Tyne, Newcastle upon Tyne NE4 6BE, England, UK
    Transplantation 76:1714-9. 2003
    ..Cardiac arrest for a protracted period of time leads to in situ thrombosis, and, as a consequence, the discard rates for harvested kidneys is higher than brain-stem-dead donors...
  43. ncbi Randomized trial of endoscopic versus open vein harvest for coronary artery bypass grafting: six-month patency rates
    Kwok L Yun
    Department of Cardiac Surgery, Kaiser Permanente Medical Center, Los Angeles, Calif, USA
    J Thorac Cardiovasc Surg 129:496-503. 2005
    ..We sought to compare the 6-month angiographic patency rates of greater saphenous veins removed during coronary artery bypass grafting with the endoscopic vein harvest or open vein harvest techniques...
  44. ncbi Effects of oocyte quality, semen donor and embryo co-culture system on the efficiency of blastocyst production in goats
    L Katska-Ksiazkiewicz
    Department of Biotechnology of Animal Reproduction, National Research Institute of Animal Production, 32 083, Balice, Poland
    Theriogenology 68:736-44. 2007
    ..Staining with BCB of COCs recovered from adult goats does not enhance efficiency of selection of developmentally competent oocytes for IVF...
  45. ncbi Effects of repetition, interval between treatments and season on the results from laparoscopic ovum pick-up in goats
    J Pierson
    Nexia Biotechnologies Inc, St Telesphore, Quebec, Canada
    Reprod Fertil Dev 16:795-9. 2004
    ..These results indicate that LOPU may be repeated up to five times in goats at different intervals and in different seasons with little or no important change in overall response...
  46. ncbi Saphenous vein conduits harvested by endoscopic technique exhibit structural and functional damage
    Laki J Rousou
    Beth Israel Deaconess Medical Center, Boston, Massachusetts, USA
    Ann Thorac Surg 87:62-70. 2009
    ..Our objective was to compare the effects of ESVH and OSVH on the structural and functional viability of saphenous vein endothelium using multiphoton imaging, immunofluorescence, and biochemical techniques...
  47. ncbi Endoscopic vs open saphenous vein harvest for coronary artery bypass grafting: a prospective randomized trial
    Jan Jesper Andreasen
    Department of Cardiothoracic Surgery, Aalborg Hospital, University of Aarhus, Hobrovej, Aalborg, Denmark
    Eur J Cardiothorac Surg 34:384-9. 2008
    ..Secondly we investigated whether EVH would reduce length of hospital stay and improve cosmetic results...
  48. ncbi Early quantitative coronary angiography of saphenous vein grafts for coronary artery bypass grafting harvested by means of open versus endoscopic saphenectomy: a prospective randomized trial
    L P Perrault
    Research Center, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada
    J Thorac Cardiovasc Surg 127:1402-7. 2004
    ..The purpose of this study was to compare early quantitative coronary analysis of saphenous vein grafts used for coronary artery bypass grafting harvested with the open versus endoscopic techniques...
  49. pmc Strategies to reduce intraluminal clot formation in endoscopically harvested saphenous veins
    Emile N Brown
    Department of Surgery, Division of Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    J Thorac Cardiovasc Surg 134:1259-65. 2007
    ..We hypothesized that endoscopic visualization facilitated by sealed carbon dioxide insufflation causes stagnation of blood within the saphenous vein. In the absence of prior heparin administration, this stasis provokes clot formation...
  50. ncbi Minimally invasive conduit harvesting: a systematic review
    Omer Aziz
    Department of Surgical Oncology and Technology, Imperial College of Science, Technology and Medicine, 10th Floor QEQM Building, St Mary s Hospital, London W2 1NY, United Kingdom
    Eur J Cardiothorac Surg 29:324-33. 2006
    ..Wounds from minimally invasively harvested venous conduits appear to be less prone to complications although more comparative evidence on conduit quality and long-term patency is eagerly awaited...
  51. pmc Laparoscopic left lateral sectionectomy in living donors: safety and reproducibility of the technique in a single center
    Olivier Soubrane
    Service de Chirurgie, Hopital Cochin, Assistance Publique Hopitaux de Paris, Universite Paris Descartes, France
    Ann Surg 244:815-20. 2006
    ..The main goal was to minimize donor morbidity while preserving the abdominal wall. Herein, we report the technical feasibility and reproducibility, and compared it with open liver resection (OLR)...
  52. ncbi Leg wound infection after coronary artery bypass grafting: a meta-analysis comparing minimally invasive versus conventional vein harvesting
    Thanos Athanasiou
    The National Heart and Lung Institute, Imperial College of Science, Technology and Medicine, Department of Cardiothoracic Surgery, St Mary s Hospital, London, United Kingdom
    Ann Thorac Surg 76:2141-6. 2003
    ..Further research is required to evaluate the potential benefits of minimally invasive vein harvesting techniques on the cost of postoperative care and quality of the harvested vein...
  53. ncbi Procedure for maximizing oocyte harvest for in vitro embryo production in small ruminants
    A Gibbons
    Instituto Nacional de Tecnologia Agropecuaria, Estación Experimental Bariloche, Bariloche, Argentina
    Reprod Domest Anim 42:423-6. 2007
    ..In summary, current results indicate that retrieval of oocytes can be maximized, without affecting oocyte quality, by repeating 'oneshot' FSH/eCG regimes and LOPUs at intervals as short as 4 days...
  54. ncbi Endoscopic vein harvest: advantages and limitations
    Pramod Bonde
    Department of Cardiac Surgery, Royal Victoria Hospital, Belfast, United Kingdom
    Ann Thorac Surg 77:2076-82. 2004
    ..Endoscopic vein harvest (EVH) attempts to reduce this morbidity and improve patient satisfaction with no compromise in outcome...
  55. ncbi Are wound healing disturbances and length of hospital stay reduced with minimally invasive vein harvest? A meta-analysis
    Thanos Athanasiou
    Department of Cardiothoracic Surgery, Imperial College of Science, Technology and Medicine, The National Heart and Lung Institute, St Mary s Hospital London, 70 St Olaf s Road, Fulham, London SW6 7DN, UK
    Eur J Cardiothorac Surg 26:1015-26. 2004
    ..This has the potential to reduce wound-related morbidity, infection, post-operative pain, length of hospital stay, and re-admission rate...
  56. ncbi Donor-site morbidity after osteochondral autologous transplantation for lesions of the talus
    J Paul
    Abteilung für Sportorthopädie, Klinikum rechts der Isar, TU Munchen, Connollystrasse 32, 80809 München, Germany
    J Bone Joint Surg Am 91:1683-8. 2009
    ..One disadvantage of this technique is the need to harvest a donor graft from a normal knee. The potentially detrimental effect of graft harvest on knee function remains unclear...
  57. ncbi Non-heart-beating donor kidneys in the Netherlands: allocation and outcome of transplantation
    Karin M Keizer
    Dutch Transplantation Foundation, Leiden, The Netherlands
    Transplantation 79:1195-9. 2005
    ..Since February 1, 2001, kidneys from both heart-beating (HB) and non-heart-beating (NHB) donors in The Netherlands have been indiscriminately allocated through the standard renal-allocation system...
  58. ncbi Minimally invasive vein harvesting significantly reduces pain and wound morbidity
    Edward A Black
    Department of Cardiothoracic Surgery, Glenfield Hospital, Groby Road, Leicester, UK
    Eur J Cardiothorac Surg 22:381-6. 2002
    ..We aimed to test the hypothesis that minimally invasive harvesting reduces post-operative pain and inflammation. A secondary objective was to determine if minimally invasive harvesting could be performed efficiently...
  59. ncbi Progression of organ failure in patients approaching brain stem death
    F T Lytle
    Division of Critical Care, Department of Anesthesiology, Mayo Clinic College of Medicine Rochester, MN, USA
    Am J Transplant 9:1446-50. 2009
    ..8 h (9.5-17.6). The fact that mean SOFA scores did not change significantly over time, even after BSD occurred, has implications for the timing of retrieval of organs for transplantation...
  60. ncbi Long-term renal function in kidneys from non-heart-beating donors: A single-center experience
    Muhammed A Gok
    Renal and Liver Transplant Unit, The Freeman Hospital, High Heaton, Newcastle upon Tyne, NE7 7DN, England, UK
    Transplantation 74:664-9. 2002
    ..NHBD renal transplants are underused because of the concern of poor quality graft function from such donors. In response to this perception, we reviewed 46 NHBD renal transplants performed in our center since 1998...
  61. ncbi A comparison of the donor-site morbidity after using the prelaminated fasciomucosal flap and the fasciocutaneous radial forearm flap for intraoral reconstruction
    G V Nehrer-Tairych
    Department of Plastic and Reconstructive Surgery, Vienna Lainz Hospital, Austria
    Br J Plast Surg 55:198-202. 2002
    ..The results of this study show that using the prelaminated fasciomucosal radial forearm flap minimises the donor-site morbidity. Furthermore, we were able to improve the cosmetic appearance of this very exposed region...
  62. ncbi Laparoscopic live donor nephrectomy in patients surgically treated for morbid obesity
    Anibal W Branco
    Section of Urology and General Surgery, Cruz Vermelha Hospital, Curitiba, Parana, Brazil
    Int Braz J Urol 33:377-9; discussion 379. 2007
    ..After bariatric surgery, both donors lost more than 30% of their initial corporal weight and their donation procedure was successfully performed, with uneventful postoperative courses...
  63. ncbi The main hepatic anatomic variations for the purpose of split-liver transplantation
    Eleazar Chaib
    Department of Gastroenterology Liver and Portal Hypertension Surgery Unit, University of Sao Paulo School of Medicine, Rua Embau 206 Ap 131, 04039 060 São Paulo, Brazil
    Hepatogastroenterology 54:688-92. 2007
    ..The aim of this study is to demonstrate the importance of an assessment of the hepatic anatomical structures for the purpose of split-liver transplantation...
  64. ncbi Organ donation and utilization, 1995-2004: entering the collaborative era
    W H Marks
    Swedish Medical Center, Seattle, WA, USA
    Am J Transplant 6:1101-10. 2006
    ..The number of living donor organs increased from 3493 in 1995 to 7002 in 2004; data show trends toward more living unrelated donors and those providing non-directed donations...
  65. ncbi Laparoscopic live donor nephrectomy: a comparison with the conventional open approach
    S L Brown
    Department of Urology and Renal Transplantation, Virginia Mason Medical Center, Seattle, Washington, USA
    J Urol 165:766-9. 2001
    ..Laparoscopic nephrectomy results in less postoperative discomfort, an improved cosmetic result and more rapid recovery for the donor with equivalent functional results and complications...
  66. ncbi Hand-assisted right laparoscopic live donor nephrectomy
    Anibal W Branco
    Department of Urology and General Surgery, Cruz Vermelha Hospital, Curitiba, Parana, Brazil
    Int Braz J Urol 31:421-9; discussion 429-30. 2005
    ..The aim of this article is to report our experience with right laparoscopic live donor nephrectomies...
  67. ncbi Should the internal thoracic artery be skeletonized?
    Thanos Athanasiou
    The National Heart and Lung Institute, Imperial College of Science, Technology and Medicine, Department of Cardiothoracic Surgery, St Mary s Hospital, London, United Kingdom
    Ann Thorac Surg 77:2238-46. 2004
    ..Advantages and disadvantages of the skeletonization technique are highlighted and discussed...
  68. ncbi Retrieving organs from non-heart-beating organ donors: a review of medical and ethical issues
    Christopher James Doig
    Department of Critical Care Medicine and The Office of Medical Bioethics, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada
    Can J Anaesth 50:1069-76. 2003
    ..One practice, used in other countries, is the recovery of organs from non-heart-beating organ donors (NHBD). The purpose of this review is to discuss ethical issues surrounding the use of organs from these donors...
  69. ncbi [Feasibility of out-of-hospital management of non-heart-beating donors in Seine-Saint-Denis: one year retrospective study]
    F Adnet
    SAMU 93, EA 3409, Hopital Avicenne, AP HP, Universite Paris 13, 125 rue de Stalingrad, Bobigny, France
    Ann Fr Anesth Reanim 28:124-9. 2009
    ..In the same time, eight brain dead donors were managed by Samu 93 and were harvested leading to transplant 16 kidneys. Finally, 50% of overall kidney transplant activity in Seine-Saint-Denis was provided by NHBD grafts...
  70. pmc The transition from open to endoscopic saphenous vein harvesting and its clinical impact: The Texas Heart Institute experience
    Tianjie Lai
    Division of Cardiovascular Surgery, Texas Heart Institute, St Luke s Episcopal Hospital, Houston, Texas 77030, USA
    Tex Heart Inst J 33:316-20. 2006
    ..Although the transition from open to endoscopic vein harvesting can be challenging in institutions, it can be successful if operators receive adequate training in endoscopic technique and are supported by surgeons and staff...
  71. ncbi Delayed graft function in kidney transplantation
    Norberto Perico
    Department of Medicine and Transplantation, Ospedali Riuniti di Bergamo Mario Negri Institute for Pharmacological Research, Bergamo, Italy
    Lancet 364:1814-27. 2004
    ....
  72. ncbi Non-heart-beating organ donation - solution or a step too far?
    D Gardiner
    Anaesthesia 62:431-3. 2007
  73. ncbi Influence of endoscopic versus traditional saphenectomy on event-free survival: five-year follow-up of a prospective randomized trial
    Keith B Allen
    Department of Cardiothoracic Surgery, St Vincent Hospital and Health Care Center, Indianapolis, Indiana, USA
    Heart Surg Forum 6:E143-5. 2003
    ..Although histologic studies suggest no significant difference in vein quality between these two techniques, long-term follow-up is lacking to address whether graft patency and event-free survival are influenced by the harvest method...
  74. pmc A prospective audit of endoscopic vein harvesting for coronary artery bypass surgery
    Zakariya Waqar-Uddin
    Department of Cardiothoracic Surgery, Lancashire Cardiac Centre, Blackpool Victoria Hospital, Blackpool, UK
    Ann R Coll Surg Engl 91:426-9. 2009
    ....
  75. ncbi Effect of intraabdominal pressure elevation and positioning on hemodynamic responses during carbon dioxide pneumoperitoneum for laparoscopic donor nephrectomy: a prospective controlled clinical study
    I R A M Mertens zur Borg
    Department of Anesthesiology, Erasmus University Medical Center, P O Box 2040, 3000, Rotterdam, CA, The Netherlands
    Surg Endosc 18:919-23. 2004
    ..This study evaluated the hemodynamic effects of elevated intraabdominal pressure (IAP) occurring during laparoscopic donor nephrectomy (LDN)...
  76. ncbi Care of the potential organ donor
    Kenneth E Wood
    Department of Medicine, University of Wisconsin Hospital and Clinics, Madison, USA
    N Engl J Med 351:2730-9. 2004
  77. ncbi Right laparoscopic live donor nephrectomy: a single institution experience
    Stephen Boorjian
    Department of Urology, Weill Cornell Medical Center, New York, NY, USA
    Transplantation 77:437-40. 2004
    ..The purpose of our study, therefore, was to report on a large, single-institution experience with right LLDN performed using a hand-assisted, transperitoneal approach...
  78. ncbi Sequential kidney/islet transplantation: efficacy and safety assessment of a steroid-free immunosuppression protocol
    C Toso
    Cell Isolation and Transplantation Center, Division of Visceral and Transplant Surgery, Geneva University Hospitals, Geneva, Switzerland
    Am J Transplant 6:1049-58. 2006
    ..The net harm versus benefit has not yet been established and will require further studies with larger numbers of enrolled subjects...
  79. ncbi Laparoscopic live donor nephrectomy
    Ben Challacombe
    Department of Transplantation, Guy s Hospital, London SE1 9RT, UK
    Nephrol Dial Transplant 19:2961-4. 2004
  80. ncbi A systematic review of laparoscopic live-donor nephrectomy
    Rebecca L Tooher
    Australian Safety and Efficacy Register of New Interventional Procedures Surgical, Royal Australasian College of Surgeons, Adelaide, South Australia, Australia
    Transplantation 78:404-14. 2004
    ..A systematic review was undertaken to assess the safety and efficacy of laparoscopic live-donor nephrectomy (LLDN) compared with open live-donor nephrectomy (OLDN)...
  81. pmc Non heart-beating donors in England
    Eleazar Chaib
    Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, Oxford, England
    Clinics (Sao Paulo) 63:121-34. 2008
    ..The aim of this study is to examine clinical outcomes of non-heart-beating donors in the past 10 years in the UK as an way of decreasing pressure in the huge waiting list for organs transplantation...
  82. ncbi Optimization of cardiac preload during laparoscopic donor nephrectomy: a preliminary study of central venous pressure versus esophageal Doppler monitoring
    L S Feldman
    Steinberg Bernstein Centre for Minimally Invasive Surgery, McGill University, Montreal, QC, Canada
    Surg Endosc 18:412-6. 2004
    ..The purpose of this study was to compare central venous pressure (CVP) monitoring with a noninvasive measure of cardiac preload (esophageal Doppler) during LDN...
  83. ncbi A meta-analysis of minimally invasive versus traditional open vein harvest technique for coronary artery bypass graft surgery
    Sheraz R Markar
    Department of Cardiothoracic Surgery, Papworth Hospital, Papworth Everard, Cambridge, UK
    Interact Cardiovasc Thorac Surg 10:266-70. 2010
    ..databases was performed using the following terms; 'saphenous vein', 'coronary artery bypass', 'tissue and organ harvesting' and 'endoscopic'. Relevant papers were then analysed using Statsdirect software...
  84. ncbi Impact of endoscopic versus open saphenous vein harvest techniques on outcomes after coronary artery bypass grafting
    Maral Ouzounian
    Division of Cardiac Surgery, Faculty of Medicine, Dalhousie University, Halifax, Nova Scotia, Canada
    Ann Thorac Surg 89:403-8. 2010
    ..Recent data, however, suggest that EVH may be associated with reduced graft patency rates. The objective of this study is to assess the effect of EVH on short-term and midterm outcomes after CABG...
  85. ncbi Leg wound infections following greater saphenous vein harvesting: minimally invasive vein harvesting versus conventional vein harvesting
    James F Reed
    Academic Affairs, Christiana Care Hospital System, Newark, Delaware 19718 6001, USA
    Int J Low Extrem Wounds 7:210-9. 2008
    ..A visual inspection of "funnel" plots suggests a mild to moderate publication bias. This meta-analysis suggests that leg wound infections and wound healing disturbances are reduced using MIVH techniques...
  86. ncbi Skeletonization of bilateral internal thoracic artery grafts lowers the risk of sternal infection in patients with diabetes
    Mark D Peterson
    Division of Cardiac Surgery, Toronto General Hospital, and Department of Surgery, University of Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 126:1314-9. 2003
    ....
  87. ncbi Early results of a non-heartbeating donor (NHBD) programme with machine perfusion
    S Balupuri
    Liver and Renal Transplant Unit, Freeman Hospital, Newcastle upon Tyne, UK
    Transpl Int 13:S255-8. 2000
    ..027, Fisher 2-tail test). Machine perfusion has been successfully introduced in phase III to the Newcastle NHBD programme and facilitates viability assessment of NHBD kidneys...
  88. ncbi Comparison of laparoscopic versus hand-assisted live donor nephrectomy
    Constantinos Kokkinos
    Imperial College London, Department of Biosurgery and Surgical Technology, St Mary s Hospital, London, United Kingdom
    Transplantation 83:41-7. 2007
    ..The aim of the present study was to compare hand-assisted laparoscopic live donor nephrectomy with the classic laparoscopic method, using meta-analytical techniques...
  89. ncbi The effect of bilateral internal thoracic artery harvesting on superficial and deep sternal infection: The role of skeletonization
    Ruggero De Paulis
    Division of Cardiac Surgery, University of Rome Tor Vergata, Italy
    J Thorac Cardiovasc Surg 129:536-43. 2005
    ..To determine the relative risk of sternal dehiscence in patients undergoing bilateral internal thoracic artery harvesting and to assess whether and to what extent the technique of artery skeletonization might reduce this risk...
  90. ncbi Oocyte recovery, embryo development and ovarian function after cryopreservation and transplantation of whole sheep ovary
    A Arav
    Institute of Animal Science, Agricultural Research Organization ARO, The Volcani Center, P O B 6, Bet Dagan 50250, Israel
    Hum Reprod 20:3554-9. 2005
    ..Successful cryopreservation of a whole ovary may provide a solution for women with premature ovarian failure. The aim of this study was to evaluate the function of cryopreserved whole sheep ovaries both in vitro and in vivo...
  91. ncbi Multiple renal arteries do not pose an impediment to the routine use of laparoscopic donor nephrectomy
    T Johnston
    Department of Surgery, University of Kentucky, Lexington, USA
    Clin Transplant 15:62-5. 2001
    ..Based on this experience, we do not find the presence of multiple renal arteries to be a barrier to the successful use of kidney grafts procured by laparoscopic donor nephrectomy...
  92. pmc Saphenous vein endothelial cell viability: a comparative study of endoscopic and open saphenectomy for coronary artery bypass grafting
    S J Alrawi
    Department of Surgery, Maimonides Medical Center, Brooklyn, New York, USA
    JSLS 5:37-45. 2001
    ..We recommend the ESVH as the procedure of choice for saphenous vein harvesting due to the lower postoperative morbidity, and the lower incubation temperature needed for its better influence on potential graft patency...
  93. ncbi Endoscopic versus open saphenous vein harvest: the effect on postoperative outcomes
    T Z Hayward
    Department of Surgery, Duke University Medical Center, Durham, North Carolina 27710, USA
    Ann Thorac Surg 68:2107-10; discussion 2110-1. 1999
    ..The purpose of this study was to objectively compare the two techniques...
  94. ncbi Time interval between FSH priming and aspiration of immature human oocytes for in-vitro maturation: a prospective randomized study
    Anne Lis Mikkelsen
    Institute for Human Reproduction, Herlev University Hospital, Fruebjergvej 3, DK 2100 Copenhagen, Denmark
    Reprod Biomed Online 6:416-20. 2003
    ..The difference was not significant. This randomized study showed no difference in apoptosis of granulosa cells and no difference in developmental competence of oocytes obtained after coasting for 3 days compared with 2 days coasting...
  95. ncbi Minimally invasive vein harvest and wound healing using the SaphLITE Retractor System
    G T Greenfield
    Cardiac and Thoracic Surgical Associates, Richmond, Virginia 23226, USA
    Ann Thorac Surg 72:S1046-9. 2001
    ..The purpose of this investigation is to determine the effectiveness of one such MIVH technology, the Genzyme SaphLITE Retractor System (Genzyme Biosurgery, Cambridge, MA)...
  96. ncbi Serial ultrasonography, hormonal profile and antisperm antibody response after testicular sperm aspiration
    G Westlander
    Centre for Reproductive Medicine, Sahlgrenska University Hospital, Goteborg University, Goteborg, Sweden
    Hum Reprod 16:2621-7. 2001
    ..In this prospective study, the physiological consequences after testicular sperm aspiration (TESA), using suction and a 19 gauge needle, were evaluated...
  97. ncbi Introduction of microsurgical technique to biliary reconstruction in living donor liver transplantation
    L Yan
    Liver Transplantation Division, Department of Surgery, West China Hospital, Sichuan University Medical School, Chengdu 61004, China
    Transplant Proc 39:1513-6. 2007
    ..High rates of biliary complications continue to be a major concern associated with living donor liver transplantation (LDLT). In this article, we report our experience of applying a microsurgical technique to biliary reconstruction in LDLT...
  98. ncbi Liver and intestine transplantation in the United States, 1996-2005
    E A Pomfret
    Lahey Clinic Medical Center, Burlington, Massachusetts, USA
    Am J Transplant 7:1376-89. 2007
    ....
  99. ncbi Reduced mortality with right-lobe living donor compared to deceased-donor liver transplantation when analyzed from the time of listing
    S A Shah
    Multi Organ Transplant Unit, University Health Network, University of Toronto, Toronto, Canada
    Am J Transplant 7:998-1002. 2007
    ..80%; p < 0.001). To our knowledge, this is the first report to document a survival advantage at time of listing for RLDLT over DDLT...
  100. ncbi Whole liver versus split liver versus living donor in the adult recipient: an analysis of outcomes by graft type
    Abhinav Humar
    Department of Surgery, University of Minnesota, Minneapolis, MN, USA
    Transplantation 85:1420-4. 2008
    ..We studied patient and graft survival rates in adult liver transplant recipients, analyzing outcomes based on donor source (deceased donor [DD] vs. living donor [LD]) and graft type (whole liver vs. partial liver)...
  101. ncbi Oral tacrolimus bioavailability is increased after right split liver transplantation
    J Wilberg
    Department of General, Visceral, and Vascular Surgery, Friedrich Schiller University, Jena, Germany
    Transplant Proc 39:3237-8. 2007
    ..Tacrolimus (Tac) is mainly metabolized in the liver. The aim of this trial was to analyze Tac bioavailability after partial liver transplantation...

Research Grants50

  1. Quality of Life Therapy for Adults with ESRD Awaiting Renal Transplantation
    James Rodrigue; Fiscal Year: 2007
    ..These benefits have the potential to extend the QOL outcomes otherwise derived from transplantation alone. [unreadable] [unreadable] [unreadable]..
  2. EVALUATION OF A CONCEPTUAL MODEL OF ORGAN DONATION
    James Rodrigue; Fiscal Year: 2004
    ..abstract_text> ..
  3. Transdermal Codrugs for Treatment of Alcoholism
    Audra Stinchcomb; Fiscal Year: 2006
    ..Correlation of the in vitro data with the in vivo model will aid in the creation of a reliable QSAR database that is necessary to help identify the best co-drugs for clinical use. ..
  4. CHOC Human Embryonic Stem Cell Culture Training Course
    Philip Schwartz; Fiscal Year: 2008
    ..The courses are held annually in the Spring at the National Human Neural Stem Cell Resource of the Neuroscience Laboratories at the Children's Hospital of Orange County Research Institute. [unreadable] [unreadable] [unreadable]..
  5. Ethnicity and Culture in Unrelated Stem Cell Donation
    Galen E Switzer; Fiscal Year: 2010
    ..abstract_text> ..
  6. MRI Evaluation of Acute Renal Transplant Dysfunction
    Vivian Lee; Fiscal Year: 2008
    ..At its conclusion, our study has a high likelihood of showing that functional MR renography for differentiating intrinsic renal diseases, will be an accurate tool for acute renal transplant dysfunction. ..
  7. Mechanisms of Nural Crest Cell Development
    Ching Pin Chang; Fiscal Year: 2010
    ..Aim #3: Define the molecular pathways affected by the absence of Pbx1. We will use standard molecular biology and embryology methods to study if Pax3 pathway is downstream of Pbx1 in cardiac development. ..
  8. LIVER REPOPULATION FOR LIVER INJURY AND GENE THERAPY
    Sanjeev Gupta; Fiscal Year: 2008
    ..Completion of our studies will generate new knowledge in liver repopulation and cell and gene therapy mechanisms. This will lead to more effective liver-directed cell and gene therapy in people. ..
  9. Clinical Utility of Endothelial Function in PAD
    Joseph Vita; Fiscal Year: 2007
    ..This work will provide novel information about the pathogenesis and management of PAD. ..
  10. FUNCTIONAL ANALYSIS OF VASCULAR NTPDASES
    Simon Robson; Fiscal Year: 2007
    ..Information gleaned from these studies may direct new therapeutic strategies for inflammatory vascular disorders, including atherosclerotic cardiovascular disease. ..
  11. Hematopoietic Stem Cell Therapy for Myocardial Regeneration
    Roberto Bolli; Fiscal Year: 2007
    ..The results may eventually lead to the development of novel therapeutic strategies in patients with ischemic heart disease. ..
  12. Binge Ethanol and Oocyte Quality
    Catherine A Vandevoort; Fiscal Year: 2010
    ..The outcome of this project will have direct relevance to the effects of binge drinking in women. ..
  13. SIGNALING PATHWAYS IN CHEMICAL INDUCED OVOTOXICITY
    Patricia B Hoyer; Fiscal Year: 2010
    ..This will lead to an appreciation of the global impact of the environment on the reproductive life span in women. ..
  14. Surgical Management of Facial Nerve Injury
    Theresa Hadlock; Fiscal Year: 2007
    ..The academic environment is one of complete dedication to advancing both biomedical science and patient care through careful study and diligent investigation, and of support for the mentored investigator. [unreadable] [unreadable]..
  15. PROTOCOLS FOR MATURING AND FREEZING MONKEY OOCYTES
    Catherine VandeVoort; Fiscal Year: 2006
    ..abstract_text> ..
  16. Effects of Fetal Bisphenol A Exposure on Oogenesis in Primates
    CATHERINE A contact VANDEVOORT; Fiscal Year: 2010
    ..Because the dose used will be similar to current human blood levels of BPA, the results should have direct relevance to human health. ..
  17. A Home Exercise Program (DVD) for Women with Infants and Young Children
    Cheryl Albright; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  18. Determinants of Shear Stress-Mediated Arterial Remodeling
    Joseph Vita; Fiscal Year: 2009
    ....
  19. Systems Engineering of Pheresis Intervention for Sepsis
    John Kellum; Fiscal Year: 2009
    ..We will also call on the expertise of two companies, one specializing in adsorbent polymer technology (MedaSorb Technologies, LLC) and the other in complex systems modeling (Immunetrics, Inc.). ..
  20. NALTREXONE PRODRUGS FOR TRANSDERMAL DELIVERY
    Audra L Stinchcomb; Fiscal Year: 2010
    ....
  21. Purinergic Thromboregulation
    Simon C Robson; Fiscal Year: 2010
    ..d) Study thrombus formation in hyperlipidemic Cd39 mutant mice. This work will provide insights into the central thromboregulatory mechanisms impacting platelet activation and vascular injury in vivo. ..
  22. Articulated Robot for Epicardial Interventions
    Marco A Zenati; Fiscal Year: 2010
    ..We also believe that the HARP may expand the therapeutic options for other non-cardiac endoscopic applications . ..
  23. Physical Activity in Women with Infants
    CHERYL LYNN ALBRIGHT; Fiscal Year: 2010
    ..This study will serve as a model for the design and implementation of PA interventions for at-risk ethnic minority postpartum women. ..
  24. Biological Markers of Recovery for the Kidney
    John A Kellum; Fiscal Year: 2010
    ..For analyses requiring serial samples and urine samples, we propose to study a subset of trial patients enrolled at 5 sites who consent to additional sample collection (208 patients) ..
  25. Long-term outcomes of head and neck cancer patients
    Gerry Funk; Fiscal Year: 2009
    ..abstract_text> ..
  26. Mechanisms of Cardioprotection
    Roberto Bolli; Fiscal Year: 2007
    ....
  27. LIVER REPOPULATION FOR LIVER INJURY AND GENE THERAPY
    Sanjeev Gupta; Fiscal Year: 2007
    ..Our studies will provide valuable preclinical information for eventual applications of cell therapy in people. ..
  28. OXYGEN RADICALS AND POSTISCHEMIC DYSFUNCTION
    Roberto Bolli; Fiscal Year: 2002
    ..Elucidation of the mechanism of late PC should facilitate the development of drugs that duplicate its powerful cardioprotective effects. ..
  29. Induction of suppression for Islet Transplantation
    Zandong Yang; Fiscal Year: 2003
    ..This study will provide an experimental strategy of using AAV vlL-10 gene therapy to investigate immunosuppression induction in islet transplantation. ..
  30. COMPREHENSIVE MR EVALUATION OF RENOVASCULAR DISEASE
    Vivian Lee; Fiscal Year: 2003
    ....
  31. UNDERSTANDING THE PATHOGENESIS OF STAPHYLOCOCCUS AUREUS
    Vance Fowler; Fiscal Year: 2003
    ..Accomplishing the aims of this proposal will contribute to improved clinical management of patients with S. aureus bacteremia, and will add to the understanding of S. aureus virulence factors. ..
  32. VASCULAR NTPDASES AND TRANSPLANTATION
    Simon Robson; Fiscal Year: 2004
    ..These experiments should delineate involvement of NTPDases and P2signaling in inflammation associated with arterial/venous injury and also culminating in allograft failure. ..
  33. Psychosocial Issues in Umbilical Cord Blood Donation
    Galen Switzer; Fiscal Year: 2004
    ..abstract_text> ..
  34. C/EBP, p300 and atrogin-1 in muscle wasting
    Amy Evenson; Fiscal Year: 2005
    ..The use of cultured muscle cells will allow for defining mechanisms of muscle wasting at the gene level. ..
  35. Chronic Lung Allograft Rejection in MHC-Defined Swine
    James Allan; Fiscal Year: 2005
    ..abstract_text> ..
  36. VLA4 IN CTL MEDIATED ISLET ALLOGRAFT REJECTION
    Mark Stegall; Fiscal Year: 2001
    ..The approach may lead to novel forms of immune suppression that may benefit not only islet transplantation, but also other types of organ allografts. ..
  37. Predictors of Living Kidney Donor Recruitment
    Peter Reese; Fiscal Year: 2006
    ..The primary outcome of successful recruitment will be registration of a potential donor at a transplant center for evaluation. [unreadable] [unreadable] [unreadable]..
  38. Defining Cell Lineages in the Bladder Urothelium
    Sabina Signoretti; Fiscal Year: 2006
    ..These studies will clarify lineage relationships among bladder epithelial cells and provide important insights into the nature of urothelial stem cells. ..
  39. Physician Peer Minority Organ Donation Education Model
    Akinlolu Ojo; Fiscal Year: 2006
    ..abstract_text> ..
  40. High Resolution In Vivo MicroCT Imaging and Analysis System for Rodents
    Douglas Adams; Fiscal Year: 2006
    ..This has been recognized as a critical issue by the Surgeon General's Report on "Bone Health and Osteoporosis". [unreadable] [unreadable]..
  41. INTERLEUKIN 6 AND HUMAN BILIARY EPITHELIAL PROLIFERATION
    Anthony Demetris; Fiscal Year: 2006
    ..abstract_text> ..
  42. Prevention of Hip Dysplasia with Thermal Energy
    MANDI LOPEZ; Fiscal Year: 2005
    ..The University of Wisconsin provides an exceptional environment for interaction with experts in a variety of fields, and it is well known for its exceptional research programs, especially in the medical sciences. ..
  43. ENVIRONMENTAL EPOXIDES--MECHANISMS OF OVOTOXICITY
    Patricia Hoyer; Fiscal Year: 2002
    ..The results of these studies will provide greater insight as to the impact of exposure to ovotoxic environmental chemicals on reproductive health in women. ..
  44. Glucose Regulation of Pancreatic Islet Gene Experession
    RODERICK PAUL ROBERTSON; Fiscal Year: 2010
    ..We will study whether increasing antioxidant protection protects these cells and prevents deterioration of glucose control in diabetes. ..
  45. Ovary Intact Murine Model for Menopause
    Patricia Hoyer; Fiscal Year: 2007
    ..Characterization of the VCD-treated mouse will, therefore, make a profound contribution to the study of menopause-related pathologies and, therefore, to women's health. ..
  46. Regulatory T cells in transplantation tolerance
    James Markmann; Fiscal Year: 2008
    ..Collectively, these studies will further our understanding of regulatory T cell function in vivo and help to define their potential for application in the clinical transplant arena. ..
  47. Magnetic Resonance Renography:Validation Studies
    Vivian Lee; Fiscal Year: 2003
    ..abstract_text> ..
  48. Ethical Issues in Behavioral Health Research
    James DuBois; Fiscal Year: 2004
    ..The Center for Health Care Ethics at Saint Louis University and the Missouri Institute of Mental Health are committed to sustaining the course beyond year 3. ..
  49. Prevention/diagnosis/fungal infections/transplantation
    Barbara Alexander; Fiscal Year: 2005
    ..This approach will shorten the time from development to clinical implementation in therapeutic trials and guidelines. ..
  50. Magnetic Separation of Liberated Islets During Isolation
    KLEARCHOS PAPAS; Fiscal Year: 2005
    ....