surgical anastomosis

Summary

Summary: Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side.

Top Publications

  1. ncbi Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: a prospective monocentric study
    Nicolas C Buchs
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Int J Colorectal Dis 23:265-70. 2008
  2. ncbi Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trial
    Claudio Bassi
    Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, Hospital G B Rossi University of Verona, Piazzale L A Scuro, 37134 Verona, Italy
    Surgery 134:766-71. 2003
  3. ncbi Impact of anastomotic leakage on long-term survival after total gastrectomy for carcinoma of the stomach
    M Sierzega
    First Department of Surgery, Jagiellonian University Medical College, Krakow, Poland
    Br J Surg 97:1035-42. 2010
  4. pmc Single-layer continuous versus two-layer interrupted intestinal anastomosis: a prospective randomized trial
    J M Burch
    Department of Surgery, Denver Health Medical Center, Denver, Colorado 80204 4507, USA
    Ann Surg 231:832-7. 2000
  5. ncbi Mortality secondary to esophageal anastomotic leak
    Khaled Alanezi
    Department of Surgery, McMaster University, Ontario, Canada
    Ann Thorac Cardiovasc Surg 10:71-5. 2004
  6. pmc Surgical management of bile duct injuries sustained during laparoscopic cholecystectomy: perioperative results in 200 patients
    Jason K Sicklick
    Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Ann Surg 241:786-92; discussion 793-5. 2005
  7. ncbi Comparison of manual and mechanical cervical esophagogastric anastomosis after esophageal resection for squamous cell carcinoma: a prospective randomized controlled trial
    Hsao Hsun Hsu
    Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, No 7, Chung Shan South Road, Taipei, Taiwan, ROC
    Eur J Cardiothorac Surg 25:1097-101. 2004
  8. pmc Anastomotic disruption after large bowel resection
    Mohammad U Nasirkhan
    Department of Surgery, University of Connecticut, Farmington, 06030, USA
    World J Gastroenterol 12:2497-504. 2006
  9. ncbi Duodenal-content reflux esophagitis induces the development of glandular metaplasia and adenosquamous carcinoma in rats
    M Pera
    Service of Gastrointestinal Surgery, IMD, Hospital Clinic, IDIBAPS, University of Barcelona Medical School, Villarroel 170, 08036 Barcelona, Spain
    Carcinogenesis 21:1587-91. 2000
  10. ncbi [Endoscopic treatment of mediastinal anastomotic leaks]
    D Schubert
    Klinik für Allgemein Viszeral und Gefässchirurgie, Otto von Guericke Universitat Magdeburg
    Zentralbl Chir 131:369-75. 2006

Detail Information

Publications235 found, 100 shown here

  1. ncbi Incidence, consequences, and risk factors for anastomotic dehiscence after colorectal surgery: a prospective monocentric study
    Nicolas C Buchs
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Int J Colorectal Dis 23:265-70. 2008
    ..This study was designed to assess the incidence, to observe the consequences, and to identify the risk factors associated with anastomotic leakage after colorectal surgery...
  2. ncbi Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trial
    Claudio Bassi
    Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, Hospital G B Rossi University of Verona, Piazzale L A Scuro, 37134 Verona, Italy
    Surgery 134:766-71. 2003
    ..There have been many techniques proposed for the reconstruction of pancreatic digestive continuity, but there have been few prospective and randomized studies that compare their efficacy...
  3. ncbi Impact of anastomotic leakage on long-term survival after total gastrectomy for carcinoma of the stomach
    M Sierzega
    First Department of Surgery, Jagiellonian University Medical College, Krakow, Poland
    Br J Surg 97:1035-42. 2010
    ..Recent studies suggest that anastomotic leak may adversely affect long-term survival in patients undergoing surgery for gastrointestinal malignancies. Data relating to total gastrectomy for gastric cancer are scarce...
  4. pmc Single-layer continuous versus two-layer interrupted intestinal anastomosis: a prospective randomized trial
    J M Burch
    Department of Surgery, Denver Health Medical Center, Denver, Colorado 80204 4507, USA
    Ann Surg 231:832-7. 2000
    ..To determine the suitability of a single-layer continuous technique for intestinal anastomosis in a surgical training program...
  5. ncbi Mortality secondary to esophageal anastomotic leak
    Khaled Alanezi
    Department of Surgery, McMaster University, Ontario, Canada
    Ann Thorac Cardiovasc Surg 10:71-5. 2004
    ..We reviewed our experience with this complication and tried to identify factors predictive of mortality after esophageal anastomotic leak...
  6. pmc Surgical management of bile duct injuries sustained during laparoscopic cholecystectomy: perioperative results in 200 patients
    Jason K Sicklick
    Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    Ann Surg 241:786-92; discussion 793-5. 2005
    ..Three patients died without surgery due to uncontrolled sepsis. One hundred seventy-five patients underwent surgical repair, with a 1.7% postoperative mortality and a complication rate of 42.9%...
  7. ncbi Comparison of manual and mechanical cervical esophagogastric anastomosis after esophageal resection for squamous cell carcinoma: a prospective randomized controlled trial
    Hsao Hsun Hsu
    Division of Thoracic Surgery, Department of Surgery, National Taiwan University Hospital and National Taiwan University College of Medicine, No 7, Chung Shan South Road, Taipei, Taiwan, ROC
    Eur J Cardiothorac Surg 25:1097-101. 2004
    ..This study was to compare the postoperative and long-term results of manual and mechanical techniques for cervical esophagogastric anastomosis after resection for squamous cell carcinoma...
  8. pmc Anastomotic disruption after large bowel resection
    Mohammad U Nasirkhan
    Department of Surgery, University of Connecticut, Farmington, 06030, USA
    World J Gastroenterol 12:2497-504. 2006
    ..Despite proper caution and excellent surgical technique, some anastomotic leaks are inevitable. The rapid identification of anastomotic leaks and the timely treatment in these cases are paramount...
  9. ncbi Duodenal-content reflux esophagitis induces the development of glandular metaplasia and adenosquamous carcinoma in rats
    M Pera
    Service of Gastrointestinal Surgery, IMD, Hospital Clinic, IDIBAPS, University of Barcelona Medical School, Villarroel 170, 08036 Barcelona, Spain
    Carcinogenesis 21:1587-91. 2000
    ....
  10. ncbi [Endoscopic treatment of mediastinal anastomotic leaks]
    D Schubert
    Klinik für Allgemein Viszeral und Gefässchirurgie, Otto von Guericke Universitat Magdeburg
    Zentralbl Chir 131:369-75. 2006
    ..This report describes our results with the endoscopic treatment of intrathoracic anastomotic leakages...
  11. ncbi Outcome after emergency surgery for acute perforated diverticulitis in 200 cases
    Jefrey Vermeulen
    Department of Surgery, MCRZ St Clara Hospital and Zuider Hospital, Rotterdam, The Netherlands
    Dig Surg 24:361-6. 2007
    ..The ideal treatment is still controversial. The object of this study was to compare patients with perforated diverticulitis treated either by resection with primary anastomosis (PA) or Hartmann's procedure (HP)...
  12. ncbi Use of self-expandable plastic stents for the treatment of esophageal perforations and symptomatic anastomotic leaks
    C M Gelbmann
    Department of Internal Medicine I, University of Regensburg, Germany
    Endoscopy 36:695-9. 2004
    ..The aim of the present study was to assess the potential of the self-expandable Polyflex plastic stent for the treatment of these conditions...
  13. ncbi Insulin-like growth factor I and truncated keratinocyte growth factor accelerate healing of left-sided colonic anastomoses
    B Egger
    Department of Visceral and Transplantation Surgery, University of Berne, Berne, Switzerland
    Br J Surg 88:90-8. 2001
    ....
  14. ncbi Anastomotic leakage following anterior resection for rectal cancer
    I Kanellos
    4th Surgical Department, Aristotle University, Thessaloniki, Greece
    Tech Coloproctol 8:s79-81. 2004
    ..The aim of this study is to present the incidence of anastomotic leakage after anterior resection for rectal cancer and to demonstrate the therapeutic approach for the treatment of this complication...
  15. ncbi Multiple arteries in live donor renal transplantation: surgical aspects and outcomes
    Bedeir Ali-El-Dein
    Urology and Nephrology Center, Mansoura University, Mansoura, Egypt
    J Urol 169:2013-7. 2003
    ..This retrospective study describes the surgical techniques and outcomes of live donor renal allografts with multiple arteries...
  16. pmc Defunctioning stoma reduces symptomatic anastomotic leakage after low anterior resection of the rectum for cancer: a randomized multicenter trial
    Peter Matthiessen
    Department of Surgery, Orebro University Hospital, Orebro, Sweden
    Ann Surg 246:207-14. 2007
    ....
  17. ncbi Successful renovascular reconstruction for renal allografts with multiple renal arteries
    Kazuhide Makiyama
    Department of Urology, Tokyo Women s Medical University, Tokyo, Japan
    Transplantation 75:828-32. 2003
    ..In the present study, we retrospectively reviewed multiple renal artery reconstruction in kidney transplantation to elucidate the usefulness of these grafts...
  18. ncbi Survival and recurrence after a sphincter-saving resection and abdominoperineal resection for adenocarcinoma of the rectum at or below the peritoneal reflection: a multivariate analysis
    Tohru Nakagoe
    First Department of Surgery, Nagasaki University School of Medicine, 1 7 1 Sakamoto, Nagasaki 852 8501, Japan
    Surg Today 34:32-9. 2004
    ....
  19. ncbi Endoscopic treatment of thoracic esophageal anastomotic leaks by using silicone-covered, self-expanding polyester stents
    Daniel Schubert
    Department of General, Visceral and Vascular Surgery, Faculty of Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Gastrointest Endosc 61:891-6. 2005
    ..The successful treatment of esophageal anastomotic insufficiencies and perforations when using covered, self-expanding metallic stents is described...
  20. ncbi Handsewn or stapled esophagogastric anastomoses after esophagectomy for cancer: meta-analysis of randomized controlled trials
    J D Urschel
    Department of Surgery, McMaster University, Hamilton, Ontario, Canada
    Dis Esophagus 14:212-7. 2001
    ..The stapled anastomotic method appears to increase operative mortality (P=0.05). Although it is difficult to explain this finding, it should not be dismissed. Several hypotheses are discussed...
  21. pmc Anastomotic leaks after intestinal anastomosis: it's later than you think
    Neil Hyman
    Dept of Surgery, Fletcher 464, University of Vermont College of Medicine, 89 Beaumont Ave, Burlington, VT 05405, USA
    Ann Surg 245:254-8. 2007
    ..We sought to use a prospective database to define the true incidence and presentation of anastomotic leakage after intestinal anastomosis...
  22. ncbi Risk factors for anastomotic leakage after anterior resection of the rectum
    P Matthiessen
    Department of Surgery, University Hospital Orebro, S 701 85 Orebro, Sweden
    Colorectal Dis 6:462-9. 2004
    ..The aim of this study was to identify risk factors for anastomotic leakage in anterior resection and to assess the role of a temporary stoma and the need for urgent re-operations in relation to anastomotic leakage...
  23. pmc Anterior resection for rectal cancer with mesorectal excision: a prospective evaluation of 622 patients
    Wai Lun Law
    Department of Surgery, Queen Mary Hospital, University of Hong Kong Medical Center, Hong Kong
    Ann Surg 240:260-8. 2004
    ..Risk factors for local recurrence and survival were also analyzed...
  24. pmc The Dutch multicenter experience of the endo-sponge treatment for anastomotic leakage after colorectal surgery
    P J van Koperen
    Department of Surgery, Academic Medical Center, P O Box 22660, 1100 A2, DD, Amsterdam, The Netherlands
    Surg Endosc 23:1379-83. 2009
    ..The aim of this study was to assess the effectiveness of endo-sponge treatment of the presacral cavity as the result of anastomotic leakage in the Netherlands...
  25. ncbi Use of endoscopic stents to treat anastomotic complications after bariatric surgery
    Steve Eubanks
    Department of Surgery, University of Missouri, Columbia, MO 65212, USA
    J Am Coll Surg 206:935-8; discussion 938-9. 2008
    ..The purpose of this study was to present outcomes of the largest series to date treating staple line complications after bariatric surgery with endoscopic covered stents...
  26. ncbi Proposal of a novel method to evaluate anastomotic tension in esophageal atresia with a distal tracheoesophageal fistula
    Masahiro Nagaya
    Department of Pediatric Surgery, Central Hospital, Aichi Prefectural Colony, 713 8 Kamiya, Kasugai, 480 0392 Aichi, Japan
    Pediatr Surg Int 21:780-5. 2005
    ..If the stretched length is more than 10 mm, it will be necessary to consider the possibility that stricture or GER may arise afterwards...
  27. ncbi Bipolar anastomosis technique (BAT) enables "fast-to-do", high-quality venous end-to-end anastomosis in a new vascular model
    Heinrich M Schubert
    Department of Plastic and Reconstructive Surgery, Medical University of Innsbruck, Austria
    J Craniofac Surg 17:772-8. 2006
    ..The average time needed for anastomosis using BAT was less than two minutes. BAT allows fast venous end-to-end anastomosis in a chicken throat vascular model...
  28. ncbi Stent implantation as a treatment option in patients with thoracic anastomotic leaks after esophagectomy
    Werner K H Kauer
    Department of Surgery SALK, Paracelsus Medizinische Privatuniversität Salzburg, Mullner Hauptstr 48, A 5020, Salzburg, Austria
    Surg Endosc 22:50-3. 2008
    ..In patients with esophagectomy and gastric pull up for esophageal carcinoma anastomotic leaks are a well-known complication and a major cause of morbidity and mortality...
  29. ncbi A meta-analysis comparing conventional end-to-end anastomosis vs. other anastomotic configurations after resection in Crohn's disease
    Constantinos Simillis
    Department of Biosurgery and Surgical Technology, Imperial College London, London, United Kingdom
    Dis Colon Rectum 50:1674-87. 2007
    ..This study compared outcomes between end-to-end anastomosis and other anastomotic configurations after intestinal resection for patients with Crohn's disease by using meta-analytical techniques...
  30. ncbi Rectal cancer surgery without mechanical bowel preparation
    F Bretagnol
    Department of Colorectal Surgery, Beaujon Hospital, Clichy, France
    Br J Surg 94:1266-71. 2007
    ..However, very few patients having rectal surgery were included in these studies. The aim of this study was to assess whether rectal cancer surgery can be performed safely without MBP...
  31. ncbi Laparoscopic reintervention for anastomotic leakage after primary laparoscopic colorectal surgery
    J Wind
    Department of Surgery, Academic Medical Centre, PO Box 22660, 1100 DD Amsterdam, The Netherlands
    Br J Surg 94:1562-6. 2007
    ..Anastomotic leakage is associated with high morbidity and mortality rates. The aim of this study was to assess the potential benefits of a laparoscopic reintervention for anastomotic leakage after primary laparoscopic surgery...
  32. ncbi Impact of stents on urological complications and health care expenditure in renal transplant recipients: results of a prospective, randomized clinical trial
    A Tavakoli
    Renal and Pancreas Transplant Unit, Manchester Royal Infirmary, Oxford Road, Manchester, United Kingdom
    J Urol 177:2260-4; discussion 2264. 2007
    ..We performed a randomized, prospective trial to compare the incidence of early urological complications and health care expenditures in renal transplant recipients with or without ureteral stenting...
  33. pmc Factors determining delay in relaparotomy for anastomotic leakage after colorectal resection
    A Doeksen
    Department of Surgery, Academic Medical Center, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    World J Gastroenterol 13:3721-5. 2007
    ..To analyze the time interval ('delay') between the first occurrence of clinical parameters associated with anastomotic leakage after colorectal resection and subsequent relaparotomy...
  34. ncbi Impact of surgeon volume and specialization on short-term outcomes in colorectal cancer surgery
    D W Borowski
    Department of Surgery, North Tyneside General Hospital, North Shields, UK
    Br J Surg 94:880-9. 2007
    ..The aim of this study was to determine the impact of surgeon volume and specialization on primary tumour resection rate, restoration of bowel continuity following rectal cancer resection, anastomotic leakage and perioperative mortality...
  35. ncbi Evaluation of the enclose proximal anastomosis device in coronary artery bypass grafting
    Sary F Aranki
    Division of Cardiac Surgery, Brigham and Women s Hospital, Boston, Massachussetts 02115, USA
    Ann Thorac Surg 80:1091-5. 2005
    ..The objective of this study was to evaluate a new proximal anastomotic device (Novare Enclose device [Novare Surgical Systems, Cupertino, CA])...
  36. ncbi Laser Doppler assessment of the influence of division at the root of the inferior mesenteric artery on anastomotic blood flow in rectosigmoid cancer surgery
    Kazuhiro Seike
    Department of General Surgery, Graduate School of Medicine, Chiba University, 1 8 1 Inohana, Chuo Ku, Chiba shi, Chiba, 260 8670, Japan
    Int J Colorectal Dis 22:689-97. 2007
    ..The aim of this study is to evaluate the influence of dividing the inferior mesenteric artery (IMA) and preserving the left colic artery (LCA) on rectosigmoid cancer surgery...
  37. ncbi Leakage after resection and intraperitoneal anastomosis for colorectal malignancy: analysis of risk factors
    Hok Kwok Choi
    Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Hong Kong SAR, China
    Dis Colon Rectum 49:1719-25. 2006
    ..The study was designed to identify the risk factors associated with anastomotic leakage after an intraperitoneal large-bowel anastomosis in patients with colorectal malignancy...
  38. ncbi Should completely intracorporeal anastomosis be considered in obese patients who undergo laparoscopic colectomy for benign or malignant disease of the colon?
    Ioannis Raftopoulos
    Division of Minimally Invasive, Bariatric and General Surgery, UPMC Shadyside and Magee Women s Hospitals, University of Pittsburgh, PA, USA
    Surgery 140:675-82; discussion 682-3. 2006
    ..The outcome of laparoscopic colectomy with completely intracorporeal anastomosis (LCIA) in obese and nonobese patients is assessed...
  39. ncbi Clinical and subclinical leaks after low colorectal anastomosis: a clinical and radiologic study
    Michael Lim
    Department of Colorectal Surgery, Leeds General Infirmary, Leeds LS1 3EX, United Kingdom
    Dis Colon Rectum 49:1611-9. 2006
    ..This study was designed to examine the natural history of subclinical leaks and their effect on bowel function and quality of life and to evaluate water-soluble contrast enema features that predict anastomotic healing after leaks...
  40. ncbi Balloon dilation of anastomotic strictures secondary to surgical repair of esophageal atresia in a pediatric population: long-term results
    Heung Kyu Ko
    Department of Radiology, Seoul Asan Medical Center, University of Ulsan College of Medicine, 388 1, Pungnap 2dong, Songpa Gu, Seoul 138 736, Korea
    J Vasc Interv Radiol 17:1327-33. 2006
    ..To evaluate the clinical effectiveness and long-term results of balloon dilation treatment for strictures secondary to surgical repair of esophageal atresia (EA) in 29 children...
  41. ncbi Results with the Heartstring anastomotic device in patients with diseased ascending aorta
    Fausto Biancari
    Division of Cardio Thoracic and Vascular Surgery, Department of Surgery, Oulu University Hospital, Oulu, Finland
    Scand Cardiovasc J 40:238-9. 2006
    ..The use of the Heartstring device (Guidant, Indianapolis, USA) to accomplish a proximal aortic anastomosis without aortic clamping has been suggested in such patients...
  42. ncbi Anastomotic leaks: what is the best diagnostic imaging study?
    G A Nicksa
    University of Connecticut Health Center and School of Medicine, Farmington, CT, USA
    Dis Colon Rectum 50:197-203. 2007
    ..The present study was designed to evaluate and compare these two common radiographic imaging modalities in detecting lower gastrointestinal anastomotic leaks...
  43. ncbi Anastomotic leakage after lower gastrointestinal anastomosis: men are at a higher risk
    Magdalena A Lipska
    Colorectal Unit, Auckland City Hospital, Auckland, New Zealand
    ANZ J Surg 76:579-85. 2006
    ..The aim of this study was to review the anastomotic leakage rates in a single Colorectal Unit and to evaluate the risk factors for anastomotic leakage after lower gastrointestinal anastomosis...
  44. ncbi The incidence of anastomotic leaks in patients undergoing colorectal surgery
    C Platell
    Colorectal Surgical Unit, Fremantle Hospital, Fremantle, WA, Australia
    Colorectal Dis 9:71-9. 2007
    ..The aim of this study was to evaluate the incidence and risk factors associated with anastomotic leakage in patients undergoing resections of the colon and rectum...
  45. ncbi Great vessel management for endovascular exclusion of aortic arch aneurysms and dissections
    P Bergeron
    Department of Thoracic and Cardiovascular Surgery, Saint Joseph Hospital, Marseille, France
    Eur J Vasc Endovasc Surg 32:38-45. 2006
    ..To evaluate a recent approach for the endovascular repair of thoracic aortic aneurysms and dissections involving the aortic arch in high risk patients (HRP)...
  46. pmc Operative strategies for diverticular peritonitis: a decision analysis between primary resection and anastomosis versus Hartmann's procedures
    Vasilis A Constantinides
    Imperial College London, Department of Biosurgery and Surgical Technology, St Mary s Hospital London, UK
    Ann Surg 245:94-103. 2007
    ..To compare primary resection and anastomosis (PRA) with and without defunctioning stoma to Hartmann's procedure (HP) as the optimal operative strategy for patients presenting with Hinchey stage III-IV, perforated diverticulitis...
  47. ncbi Treatment of anastomotic leakage after rectal resection with transrectal vacuum-assisted drainage (VAC). A method for rapid control of pelvic sepsis and healing
    Carl Frederik Nagell
    Department of Surgical Gastroenterology, Hvidovre University Hospital, Kettegaards Alle, 2650, Hvidovre, Copenhagen, Denmark
    Int J Colorectal Dis 21:657-60. 2006
    ..In this paper, we describe VAC as a method for treating anastomotic leakage after rectal resection...
  48. ncbi Routine mobilization of the splenic flexure is not necessary during anterior resection for rectal cancer
    D J Brennan
    UCD School of Medicine and Medical Science, UCD Conway Institute, University College Dublin, Dublin, Ireland
    Dis Colon Rectum 50:302-7; discussion 307. 2007
    ..It was our hypothesis that selective splenic flexure mobilization would reduce operative times without increasing morbidity or affecting cure...
  49. ncbi Fluoroscopically guided balloon dilation for benign anastomotic stricture after Ivor-Lewis esophagectomy: experience in 62 patients
    Hyo Cheol Kim
    Department of Radiology and Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388 1, Pungnap 2dong, Songpa Gu, Seoul 138 736, Korea
    J Vasc Interv Radiol 16:1699-704. 2005
    ..To evaluate the safety and clinical effectiveness of fluoroscopically guided balloon dilation in 62 patients with benign anastomotic stricture after Ivor-Lewis esophagectomy...
  50. ncbi Gaseous and solid cerebral microembolization during proximal aortic anastomoses in off-pump coronary surgery: the effect of an aortic side-biting clamp and two clampless devices
    Lorenzo Guerrieri Wolf
    Department of Cardiothoracic Surgery, John Radcliffe Hospital, Oxford, United Kingdom
    J Thorac Cardiovasc Surg 133:485-93. 2007
    ....
  51. ncbi Initial clinical experience with the Heartstring
    Toshinobu Kazui
    Department of Cardiovascular Surgery, Cardiovascular Center, Hokkaido Ohno Hospital, 4 1 1 30 Nishino Nishi ku, Sapporo, Hokkaido 063 0034, Japan
    Jpn J Thorac Cardiovasc Surg 54:424-8. 2006
    ..We have applied the device not only to low-risk patients with normal aortas but also to high-risk patients with diseased aortas. The purpose of this study was to investigate the initial outcomes of using this device...
  52. ncbi Endoscopic vacuum-assisted closure of anastomotic leakage following anterior resection of the rectum: a new method
    Rolf Weidenhagen
    Department of Surgery, Klinikum Grosshadern, Ludwig Maximilian University of Munich, Marchioninistr, 15, D 81377, Munich, Germany
    Surg Endosc 22:1818-25. 2008
    ..This report describes a new method of endoscopic management of large anastomotic leakage in these patients...
  53. ncbi The fate of anastomotic sinuses after total mesorectal excision for rectal cancer
    N Arumainayagam
    Department of General and Colorectal Surgery, North Bristol NHS Trust, Bristol, UK
    Colorectal Dis 11:288-90. 2009
    ..The aim of this study was therefore to report the incidence and outcome of anastomotic sinuses, thus identifying those at potential risk of malignant change...
  54. ncbi Incidence of anastomotic leak in patients undergoing elective colon resection without mechanical bowel preparation: our updated experience and two-year review
    Lisa J Harris
    Department of Surgery, Division of Colon and Rectal Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Am Surg 75:828-33. 2009
    ..Vigilance for anastomotic leak must be maintained at all times, especially in patients with comorbidities that predispose to anastomotic leak...
  55. ncbi Central pancreatectomy: single-center experience of 50 cases
    Mustapha Adham
    Hospices Civils de Lyon, Department of Hepato Bilio Pancreatic Surgery and Transplantation, Hopital Edouard Herriot, 5 Place d Arsonval, 69437 Lyon Cedex 03, France
    Arch Surg 143:175-80; discussion 180-1. 2008
    ..In our series, central pancreatectomy led to effective preservation of both cephalic and distal pancreatic remnants without a significant increase in postoperative morbidity compared with conventional pancreatectomy...
  56. ncbi Mechanical bowel preparation for elective colorectal surgery: a multicentre randomised trial
    Caroline M E Contant
    Department of Surgery, Ikazia Hospital, Rotterdam, Netherlands
    Lancet 370:2112-7. 2007
    ..We aimed to compare the rate of anastomotic leakage after elective colorectal resections and primary anastomoses between patients who did or did not have mechanical bowel preparation...
  57. ncbi Risk factors and clinical outcome for anastomotic leakage after total mesorectal excision for rectal cancer
    Won Suk Lee
    Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 50 Irwon dong, Gangnam Gu, Seoul 135 710, Korea
    World J Surg 32:1124-9. 2008
    ....
  58. ncbi Pancreatic anastomotic leak after the Whipple procedure is reduced using the surgical microscope
    Keita Wada
    Department of General, Vascular, and Thoracic Surgery, Virginia Mason Clinic, Seattle, WA 98111, USA
    Surgery 139:735-42. 2006
    ..In this study we tested the hypothesis that better vision would improve the technical performance of this anastomosis and result in a lower Leak rate...
  59. ncbi Recommendation for appropriate use of GRF glue in the operation for acute aortic dissection
    Takashi Kunihara
    Department of Cardiovascular Surgery, Hokkaido University Hospital, Sapporo, Japan
    Ann Thorac Cardiovasc Surg 14:88-95. 2008
    ..We compare our midterm surgical results for acute aortic dissection with and without the use of GRF glue...
  60. ncbi Restoration of bowel continuity after surgery for acute perforated diverticulitis: should Hartmann's procedure be considered a one-stage procedure?
    J Vermeulen
    Department of Surgery, Erasmus Medical Centre, Rotterdam, The Netherlands
    Colorectal Dis 11:619-24. 2009
    ..The aim of this study was to assess differences in the rate of stomal reversal after HP and PA with DI and to evaluate factors associated with postreversal morbidity in patients operated for acute perforated diverticulitis...
  61. ncbi Effect of systemic corticosteroids on elective left-sided colorectal resection with colorectal anastomosis
    Christophe Tresallet
    Department of General and Digestive Surgery, Groupe Hospitalier Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Universite Pierre et Marie Curie Paris VI, 75651 Paris Cedex 13, France
    Am J Surg 195:447-51. 2008
    ..The impact of systemic steroid therapy on surgical outcome after elective left-sided colorectal resection with rectal anastomosis is not well known...
  62. ncbi Risk factors for anastomotic leakage after rectal cancer surgery: a case-control study
    P Jestin
    Department of Surgical Sciences, University Hospital, Uppsala, Sweden
    Colorectal Dis 10:715-21. 2008
    ..One drawback, however, is the high anastomotic leakage rate of approximately 10-18%. Male gender and low anastomoses are known risk factors for such leakage. The aim of this study was to identify potentially modifiable risk factors...
  63. ncbi Laparoscopic colorectal resections with transvaginal specimen extraction for severe endometriosis
    L Boni
    Department of Surgical Sciences, Varese, Italy
    Surg Oncol 16:S157-60. 2007
    ..Transvaginal approach, used for several years to remove large specimens, can be an interesting approach also in case of colorectal resections...
  64. ncbi Is routine ureteral stenting cost-effective in renal transplantation?
    Derek A DuBay
    Department of Surgery, University of Michigan Health System, Ann Arbor, Michigan 48109 0331, USA
    J Urol 178:2509-13; discussion 2513. 2007
    ..We identified the specific morbidity associated with urinary complications following renal transplantation and quantified the health care resources required to treat these patients at a high volume center...
  65. ncbi Risk factors and oncologic impact of anastomotic leakage after rectal cancer surgery
    Sang Hun Jung
    Colorectal Clinic, Department of Surgery, University of Ulsan College of Medicine, and Asan Medical Center, Seoul, Korea
    Dis Colon Rectum 51:902-8. 2008
    ..The impact of anastomotic leakage on the long-term oncologic outcome is not clear. This retrospective study evaluated risk factors and oncologic impacts of anastomotic leakage after rectal cancer surgery...
  66. ncbi Elective colorectal surgery without bowel preparation: a historical control and case-matched study
    D Pitot
    Clinic of Colorectal Surgery, Department of Digestive Surgery, Hôpital Erasme ULB, Brussels, Belgium
    Acta Chir Belg 109:52-5. 2009
    ..The aim of this study was to assess the safety of ileocolic, colocolic and colorectal anastomosis in the absence of pre-operative mechanical bowel preparation...
  67. ncbi Endo-vacuum assisted closure treatment for rectal anastomotic insufficiency
    Soeren Torge Mees
    Department of General Surgery, University Hospital of Muenster, Waldeyerstr 1, 48149 Muenster, Germany
    Dis Colon Rectum 51:404-10. 2008
    ..In order to prevent prolonged wound closure and secondary complications during conservative treatment we investigated the vacuum assisted closure (VAC) in this setting...
  68. ncbi Bile duct injuries related to misplacement of "T tubes"
    Miguel Angel Mercado
    Department of Surgery, Instituto Nacioonal de Ciencias Médicas y Nutición Salvador Zubirán, Mexico, D F
    Ann Hepatol 5:44-8. 2006
    ..Inadequate placement of the T tube, long term stay and technical difficulties that can affect the outcome, can lead to an injury that usually requires a biliodigestive reconstruction...
  69. ncbi Impact of anastomotic leakage on oncological outcome after rectal cancer resection
    H Ptok
    Institute for Quality Control in Operative Medicine, Otto von Guericke University Magdeburg, Magdeburg, Germany
    Br J Surg 94:1548-54. 2007
    ..Its relevance to oncological outcome is controversial. This observational study investigated the influence of anastomotic leakage on oncological outcome...
  70. ncbi The threat of adhesive embolization: BioGlue leaks through needle holes in aortic tissue and prosthetic grafts
    Scott A LeMaire
    The Texas Heart Institute, St Luke s Episcopal Hospital, Division of Cardiothoracic Surgery, The Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA
    Ann Thorac Surg 80:106-10; discussion 110-1. 2005
    ..The purpose of this study was to determine if BioGlue leaks through anastomotic needle holes in aortic tissue and two common prosthetic graft materials...
  71. ncbi Transvaginal extraction of the specimen after total laparoscopic right hemicolectomy with intracorporeal anastomosis
    Morris E Franklin
    Texas Endosurgery Institute, San Antonio, TX, USA
    Surg Laparosc Endosc Percutan Tech 18:294-8. 2008
    ..After completing a totally laparoscopic right colectomy with intracorporeal anastomosis and transvaginal extraction, an excellent postoperative recovery was demonstrated and has shown future potential for natural orifice surgery...
  72. ncbi Femoral cannulation is safe for type A dissection repair
    Daniel S Fusco
    Section of Cardiothoracic Surgery, Yale University School of Medicine, New Haven, Connecticut, USA
    Ann Thorac Surg 78:1285-9; discussion 1285-9. 2004
    ..My colleagues and I sought to determine whether these concerns are justified...
  73. ncbi Anastomotic leakage after elective right versus left colectomy for cancer: prevalence and independent risk factors
    Nicolas Veyrie
    Department of Digestive Surgery, Hopital Hotel Dieu, APHP, University of Paris V, Paris, France
    J Am Coll Surg 205:785-93. 2007
    ..Anastomotic leakage in colorectal surgery remains a major challenge because of its early and late consequences...
  74. ncbi Long-term, health-related, quality of life comparison in patients undergoing single stage vs staged resection for complicated diverticular disease
    V A Constantinides
    Imperial College London, Department of Surgical Oncology and Technology, St Mary s Hospital, London, United Kingdom
    Colorectal Dis 8:663-71. 2006
    ..To evaluate long-term health-related quality of life, for single-staged and staged resections following reversal, for complicated diverticular disease...
  75. ncbi Primary anastomosis or Hartmann's procedure for patients with diverticular peritonitis? A systematic review
    Leon Salem
    Department of Surgery, University of Washington, Seattle, Washington 98195 6410, USA
    Dis Colon Rectum 47:1953-64. 2004
    ..This systematic literature review was designed to summarize and compare the reported outcomes of one-stage and two-stage operations for the treatment of perforated diverticulitis with peritonitis...
  76. ncbi Long-term functional and quality of life outcomes after coloanal anastomosis for distal rectal cancer
    Imran Hassan
    Division of Colon and Rectal Surgery, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Dis Colon Rectum 49:1266-74. 2006
    ..This study was designed to evaluate the long-term functional and quality-of-life outcomes of patients after coloanal anastomosis for distal rectal cancer...
  77. ncbi Laparoscopic repair of superior mesenteric artery syndrome
    W S Richardson
    Department of Surgery, Ochsner Medical Institutions, Ochsner Clinic, 1514 Jefferson Highway, New Orleans, LA 70121, USA
    Am J Surg 181:377-8. 2001
    ..It is caused by decreasing the angle between the aorta and superior mesenteric artery causing compression of the third part of the duodenum and usually occurs after a period of weight loss...
  78. ncbi Technical considerations using a composite graft for aortic root replacement
    Hiroyuki Tanaka
    Departments of Thoracic and Cardiovascular Surgery, Showa University Fujigaoka Hospital, 1 30 Fujigaoka, Aoba ku, Yokohama 227 8501, Japan
    Surg Today 34:289-92. 2004
    ..Our technique of aortic root replacement based on a composite graft with some operative modifications seems to be safe and reliable, resulting in a satisfactory outcome...
  79. ncbi Early symptomatic strictures after gastric surgery: palliation with balloon dilation and stent placement
    Jin Hyoung Kim
    Department of Radiology, Asan Medical Center, University of Ulsan College of Medicine, 388 1, Poongnap 2dong, Songpa Gu, Seoul 138 736, Republic of Korea
    J Vasc Interv Radiol 19:565-70. 2008
    ..To evaluate the clinical efficacy and safety of balloon dilation and stent placement in the treatment of early benign anastomotic strictures after gastric surgery...
  80. ncbi Sutureless coronary artery bypass with biologic glued anastomoses: preliminary in vivo and in vitro results
    S R Gundry
    Loma Linda University Medical Center, Loma Linda, CA 92354, USA
    J Thorac Cardiovasc Surg 120:473-7. 2000
    ..We used a double-balloon catheter as a temporary internal stent to create and seal the anastomosis during gluing...
  81. pmc Treatment of thoracic anastomotic leaks after esophagectomy with self-expanding plastic stents
    Michael Hunerbein
    Department of Surgery and Surgical Oncology, Charitè Campus Buch and Helios Hospital, Berlin, Germany
    Ann Surg 240:801-7. 2004
    ..To evaluate the efficacy of a self-expanding plastic stent in the treatment of thoracic leaks after esophagectomy for cancer...
  82. ncbi ASGE/SAGES Working Group on Natural Orifice Translumenal Endoscopic Surgery. October 2005
    D Rattner
    SAGES ASGE Working Group on Natural Orifice Translumenal Endoscopic Surgery, USA
    Surg Endosc 20:329-33. 2006
  83. ncbi Tacrolimus enhances colon anastomotic healing in rats
    Teruo Kiyama
    Department of Surgery I, Nippon Medical School, Tokyo, Japan
    Wound Repair Regen 10:308-13. 2002
    ..These data suggest that tacrolimus enhances wound strength during acute anastomotic healing despite a reduction in collagen content...
  84. ncbi Prospective study of primary anastomosis following sigmoid resection for suspected acute complicated diverticular disease
    A W Gooszen
    Departments of Surgery, Utrecht University Hospital, Utrecht, The Netherlands
    Br J Surg 88:693-7. 2001
    ..CONCLUSION: Primary anastomosis is safe and effective in non-obstructed cases of complicated diverticular disease. Colonic obstruction seems to be a risk factor for the development of postoperative complications...
  85. ncbi Laparoscopic management of surgical complications after a recent laparotomy
    D Rosin
    The Department of General Surgery and Transplantation, Sheba Medical Center, Tel Hashomer, Israel
    Surg Endosc 18:994-6. 2004
    ..We report our experience with the use of laparoscopy for the treatment of postoperative complications, after open abdominal procedures...
  86. ncbi A polymeric sealant inhibits anastomotic suture hole bleeding more rapidly than gelfoam/thrombin: results of a randomized controlled trial
    Marc Glickman
    Virginia Vascular Associates, 880 Kempsville Rd, Suite 1000, Norfolk, VA 23502, USA
    Arch Surg 137:326-31; discussion 332. 2002
    ..An experimental polymeric sealant (CoSeal [Cohesion Technologies, Palo Alto, Calif]) provides equivalent anastomotic sealing to Gelfoam (Upjohn, Kalamazoo, Mich)/thrombin during surgical placement of prosthetic vascular grafts...
  87. ncbi First clinical experience with the HEARTSTRING, a device for proximal anastomoses in coronary surgery
    Calin Vicol
    Department of Cardiac Surgery, Grosshadern Medical Center, Ludwig Maximilians University Munich, Munich, Germany
    Ann Thorac Surg 79:1732-7; discussion 1737. 2005
    ..The HEARTSTRING is a device designed to enable the creation of a clampless hand-sewn proximal anastomosis...
  88. ncbi [Laparoscopic right hemicolectomy with intracorporeal anastomosis. Technical aspects and personal experience]
    L Casciola
    Chirurgia Vascolare e Mininvasiva, ASL n 3 dell Umbria, Spoleto, Italy
    Minerva Chir 58:621-7. 2003
    ..A great part of surgeons perform right hemicolectomy by laparo-assisted technique and consider it more difficult than left hemicolectomy...
  89. ncbi Impact of a self-expanding, plastic esophageal stent on various esophageal stenoses, fistulas, and leakages: a single-center experience in 39 patients
    Klaus Radecke
    Department of Gastroenterology and Hepatology, University of Duisberg Essen, Essen, Germany
    Gastrointest Endosc 61:812-8. 2005
    ..The majority of placements were difficult to treat situations, i.e., proximal or extremely proximal stent release or emergency cases in the intensive care unit...
  90. ncbi Intraperitoneal administration of the angiogenesis inhibitor thalidomide does not impair anastomotic healing following large bowel resection in a rabbit model
    Julian W Mall
    Department of General, Visceral, Thoracic and Vascular Surgery, Medical Faculty of the Humboldt University, Berlin, Charite, Campus Mitte, Schumannstrasse 20 21, 10117 Berlin, Germany
    World J Surg 27:1119-23. 2003
    ..The intraperitoneal administration of thalidomide does not interfere with the healing of colonic anastomosis. Although the angiogenesis score is diminished at day 3, this did not lead to a reduced bursting pressure at day 3 or day 7...
  91. ncbi Management of colorectal injuries during operation iraqi freedom: patterns of stoma usage
    James E Duncan
    Department of Surgery, National Naval Medical Center, Bethesda, Maryland, USA
    J Trauma 64:1043-7. 2008
    ..With this in mind, we evaluated how injuries to the colon and rectum were managed in the ongoing war in Iraq...
  92. ncbi A pilot study of intrastricture steroid versus placebo injection after balloon dilatation of Crohn's strictures
    James E East
    Wolfson Unit for Endoscopy, St Mark s Hospital, Harrow, Middlesex, United Kingdom
    Clin Gastroenterol Hepatol 5:1065-9. 2007
    ..Intrastricture steroid injection after balloon dilatation has been reported to reduce the need for repeat dilatation in retrospective series, but no randomized data are available...
  93. ncbi Microvascular hepatic artery reconstruction in pediatric abdominal transplantation: pearls and pitfalls
    Richard Bodor
    Veterans Affairs Medical Center, San Diego Division of Plastic and Reconstructive Surgery, University of California San Diego, 200 West Arbor Drive, San Diego, CA 92103, USA
    Pediatr Transplant 11:471-6. 2007
    ..We describe our technique of hepatic artery reconstruction and offer a systematic and multi-team collaborative approach that optimizes surgical outcomes...
  94. ncbi Colonic resection in the setting of damage control laparotomy: is delayed anastomosis safe?
    Preston R Miller
    Department of Surgery, Wake Forest University, Winston Salem, North Carolina 27157, USA
    Am Surg 73:606-9; discussion 609-10. 2007
    ..To our knowledge, this represents the first reported series of DA after DCL, an area in which further work is needed to carefully define indications for the safe application of this concept...
  95. ncbi A comparative study of laparoscopy-assisted pull-through and open pull-through for Hirschsprung's disease with special reference to postoperative fecal continence
    Naho Fujiwara
    Department of Pediatric General and Urogenital Surgery, Juntendo University School of Medicine, Tokyo 113 8421, Japan
    J Pediatr Surg 42:2071-4. 2007
    ..The objective of this study is to compare laparoscopy-assisted pull-through (LPT) and open pull-through (OPT) for Hirschsprung's disease with special reference to postoperative fecal continence...
  96. ncbi Long-term outcomes of laparoscopic versus open ileocolic resection for Crohn's disease: follow-up of a prospective randomized trial
    Luca Stocchi
    Department of Colorectal Surgery, Cleveland Clinic, Cleveland, OH 44195, USA
    Surgery 144:622-7; discussion 627-8. 2008
    ....
  97. ncbi Safety and morbidity after ultra-low coloanal anastomoses: J-pouch vs end-to-end reconstruction
    Thomas Steffen
    Department of Surgery, Cantonal Hospital of St Gallen, St Gallen, Switzerland
    Int J Colorectal Dis 23:277-81. 2008
    ..The aim of this study was to compare retrospectively the straight coloanal anastomosis with the J-pouch reconstruction concerning the development of anastomotic leakage...
  98. ncbi Evaluation of selective defunctioning stoma after low anterior resection for rectal cancer
    B Lefebure
    Department of Digestive Surgery, Rouen University Hospital, Rouen Cedex 76031, France
    Int J Colorectal Dis 23:283-8. 2008
    ..In our department, the indication of DS was evaluated subjectively by the operating surgeon. The aim of this study was to evaluate the selective use of fecal diversion...
  99. ncbi Primary pull-through with modified Duhamel technique: 1 institution's experience
    Piyawan Chiengkriwate
    Pediatric Surgery Unit, Department of Surgery, Faculty of Medicine, Prince of Songkla University, Hatyai, Songkhla 90110, Thailand
    J Pediatr Surg 42:1075-80. 2007
    ..The aim of this study was to review the early experiences in our institution with the primary pull-through option...
  100. ncbi Surgical strategy to establish a dual-coronary system for the management of anomalous left coronary artery origin from the pulmonary artery
    Bahaaldin Alsoufi
    King Faisal Heart Institute, King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia
    Ann Thorac Surg 86:170-6. 2008
    ..If the anomalous coronary arises at a long distance from the aorta, we use various coronary extension techniques to facilitate tension-free implantation...
  101. ncbi Combining classic surgery with descending stent grafting for acute DeBakey type I dissection
    Heinz Jakob
    Department of Thoracic and Cardiovascular Surgery, West German Heart Center Essen, University Hospital Essen, Essen, Germany
    Ann Thorac Surg 86:95-101. 2008
    ....

Research Grants26

  1. The Prevalence of Barrett's Esophagus in Patients with *
    Blair Jobe; Fiscal Year: 2004
    ..In addition, this study will enhance our understanding of the natural history of esophageal injury in patients with extraesophageal reflux and raise awareness of non-GERD risk factors. ..
  2. Biologically inspired engineering of hierarchical vascular networks
    George Eng; Fiscal Year: 2013
    ..important because it creates a specific inlet and outlet for in vitro connectivity and clear ends for surgical anastomosis in vivo, while maintaining a micro vascular network for efficient nutrient delivery...
  3. BLOOD FLOW IN THE DENERVATED ISCHEMIC REPERFUSED LIVER
    ANTHONY KOO; Fiscal Year: 1990
    ..the donor liver is denervated and non-perfused by blood (an ischemic organ), but it is reperfused after the surgical anastomosis of blood vessels has been completed...
  4. CAROTID OCCLUSION SURGERY STUDY
    William J Powers; Fiscal Year: 2010
    ..Previous PET studies have demonstrated that surgical anastomosis of the superficial temporal artery to the middle cerebral artery (STA-MCA) can restore OEF to normal...
  5. CAROTID OCCLUSION SURGERY STUDY
    William Powers; Fiscal Year: 2000
    ..5 percent in 39 patients with increased OEF (p=.004). Previous studies have demonstrated that surgical anastomosis of the superficial temporal artery to the middle cerebral artery (STA-MCA) can restore these hemodynamic ..
  6. Gene Transfer in Spinal Root Trauma
    Marina Mata; Fiscal Year: 2006
    ..is in the spinal root, close to the cell body, axonal injury leads to neuron cell death and even prompt surgical anastomosis of the proximal root to the distal nerve is ineffective in restoring function...
  7. Clinical Approaches to Ileal Pouch Dysfunction
    Bo Shen; Fiscal Year: 2005
    ..The AIMS of study are to 1) investigate visceral hypersensitivity using barostat examination of the pouch; 2) conduct a randomized, placebo-controlled clinical trial evaluating the use of amitriptyline in IPS. ..
  8. The Regulation of VEGF-C by Interstitial Flow
    Jeremy Goldman; Fiscal Year: 2008
    ..Therefore, we aim to determine whether an augmentation of fluid channel formation will increase interstitial flow and promote functional lymphangiogenesis in experimental lymphedema. [unreadable] [unreadable] [unreadable]..
  9. Augmentation of Lymphangiogenesis by Increased Fluid Channeling in Mouse Skin
    Jeremy Goldman; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  10. Influence of Tumor Immunogenicity to Immunotherapy
    Jeffrey Norton; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  11. IMPACT OF STANDARDIZATION AND PROCEDURE OPTIMIZATION ON*
    Ahmed Gaber; Fiscal Year: 2005
    ..This team has worked well together with the aim of curing diabetes through islet transplantation. ..
  12. ENHANCEMENT OF HUMAN ISLET ENGRAFTMENT BY GENE THERAPY
    A Gaber; Fiscal Year: 2003
    ..Future experiments based on the findings of this research would allow us to examine the utility of other gene candidates or other vectors that could complement our gene therapy program in islet transplantation. ..
  13. INJURY TO LIVER SINUSOIDAL ENDOTHELIAL CELLS
    Steven Strasberg; Fiscal Year: 2003
    ..A potentially beneficial improvements in preservation solutions are identified they will be tested in whole isolated livers and by transplantation in the rat. ..
  14. Ischemia-Reperfusion Injury in Cardiac Surgery
    William Holman; Fiscal Year: 2004
    ....
  15. Real-time multiphoton microscopy of periprostatic tissue architecture
    Ashutosh K Tewari; Fiscal Year: 2010
    ..The dynamic, high-resolution optical images achieved could empower cancer surgeons to better distinguish tissue morphology during surgery, leading to improved functional outcomes and quality of life for their patients. ..
  16. Mechanisms of ileal-induced weight loss
    APRIL STRADER; Fiscal Year: 2005
    ..Together these specific aims will help clarify the mechanisms underlying obesity surgery and may contribute to the development of more effective treatments for obesity. ..
  17. MMP-9 in Blood-Brain Barrier Failure in Fulminant Hepatic Failure
    Justin Nguyen; Fiscal Year: 2009
    ..Specific Aim 2: To determine if inhibition of MMP-9 results in an increase in survival in experimentally induced FHF. ..
  18. MMP-9 mediates cerebral edema in fulminant liver failure
    Justin Nguyen; Fiscal Year: 2004
    ..2. To determine whether cerebral edema is attenuated in MMP-9 knockout mice following experimentally induced FHF. ..
  19. Effect of Dietary Supplements in African American Kidney Transplant Recipients
    Ahmed Gaber; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  20. Biomarkers of COX-2 inhibitors in intraductal papillary mucinous neoplasm (IPMN)
    Christian Schmidt; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  21. Mechanical Stretch and Vein Graft Intimal Hyperplasia
    Jeremy Goldman; Fiscal Year: 2005
    ..Specific Aim II: Investigate the role of platelet-derived growth factor (PDGF)-BB and related signaling molecules in mediating subsequent vascular cell proliferation. ..
  22. Transfer of the CD40 ligand gene to esophageal carcinoma
    Robert Korst; Fiscal Year: 2007
    ..This study will help determine if intratumoral administration of the AdCUCD40L vector is safe, and evokes sufficient DC-related host responses to warrant further studies in esophageal cancer. ..
  23. RADIATION ARTERIOPATHY IN A TRANSGENIC AV FISTULA MODEL
    Michael Lawton; Fiscal Year: 2004
    ..If NO and TGF-01 are involved in the radiation arteriopathy of AVMs, they might be used to enhance the efficacy of conventional stereotactic radiosurgery as part of a gene therapy for high-grade cerebral AVMs. ..
  24. QUANTIFICATION OF FACTORS LEADING TO VEIN GRAFT FAILURE
    Daniel Leotta; Fiscal Year: 2004
    ..By developing methods to detect the early indicators of impending failure, this project offers the opportunity to extend the useful life of the grafts by permitting early treatment of the lesions. ..
  25. ROLE OF HYALURONAN IN INFLAMMATORY BOWEL DISEASE
    Scott Strong; Fiscal Year: 2005
    ..abstract_text> ..
  26. Genotype /phenotype correlations in infertility
    LAWRENCE LAYMAN; Fiscal Year: 2006
    ..The elucidation and analysis of gene mutations in infertile patients will be important to determine the genetic basis of some forms of infertility and to determine the underlying mechanisms of puberty and reproduction...