reoperation

Summary

Summary: A repeat operation for the same condition in the same patient due to disease progression or recurrence, or as followup to failed previous surgery.

Top Publications

  1. ncbi Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030
    Steven Kurtz
    Exponent Inc, 3401 Market Street, Suite 300, Philadelphia, PA 19104, USA
    J Bone Joint Surg Am 89:780-5. 2007
  2. ncbi Health-related quality of life in total hip and total knee arthroplasty. A qualitative and systematic review of the literature
    Olivier Ethgen
    WHO Collaborating Center for Public Health Aspects of Osteoarticular Diseases, Department of Public Health, Epidemiology, and Health Economics, University of Liege, Belgium, Liege, Belgium
    J Bone Joint Surg Am 86:963-74. 2004
  3. ncbi Registration completeness in the Norwegian Arthroplasty Register
    Birgitte Espehaug
    The Norwegian Arthroplasty Register, Department of Orthopedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 77:49-56. 2006
  4. ncbi The Norwegian Arthroplasty Register: 11 years and 73,000 arthroplasties
    L I Havelin
    Department of Orthopaedic Surgery, Haukeland University Hospital, Norway
    Acta Orthop Scand 71:337-53. 2000
  5. pmc Uncemented and cemented primary total hip arthroplasty in the Swedish Hip Arthroplasty Register
    Nils P Hailer
    Department of Orthopaedics, Institute of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Acta Orthop 81:34-41. 2010
  6. pmc The epidemiology of revision total knee arthroplasty in the United States
    Kevin J Bozic
    Department of Orthopaedic Surgery and Philip R Lee Institute for Health Policy Studies, University of California, San Francisco, 500 Parnassus Ave, MU320W, San Francisco, CA 94143 0728, USA
    Clin Orthop Relat Res 468:45-51. 2010
  7. ncbi Prevalence of primary and revision total hip and knee arthroplasty in the United States from 1990 through 2002
    Steven Kurtz
    Exponent Inc, 3401 Market Street, Suite 300, Philadelphia, PA 19104, USA
    J Bone Joint Surg Am 87:1487-97. 2005
  8. ncbi More re-operations after uncemented than cemented hemiarthroplasty used in the treatment of displaced fractures of the femoral neck: an observational study of 11,116 hemiarthroplasties from a national register
    J E Gjertsen
    Haukeland University Hospital, Department of Orthopaedic Surgery, N 5021 Bergen, Norway
    J Bone Joint Surg Br 94:1113-9. 2012
  9. pmc The Nordic Arthroplasty Register Association: a unique collaboration between 3 national hip arthroplasty registries with 280,201 THRs
    Leif I Havelin
    The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 80:393-401. 2009
  10. pmc Patient characteristics affecting the prognosis of total hip and knee joint arthroplasty: a systematic review
    Pasqualina L Santaguida
    Evidence Based Practice Centre, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario
    Can J Surg 51:428-36. 2008

Detail Information

Publications330 found, 100 shown here

  1. ncbi Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030
    Steven Kurtz
    Exponent Inc, 3401 Market Street, Suite 300, Philadelphia, PA 19104, USA
    J Bone Joint Surg Am 89:780-5. 2007
    ..The purpose of this study was to formulate projections for the number of primary and revision total hip and knee arthroplasties that will be performed in the United States through 2030...
  2. ncbi Health-related quality of life in total hip and total knee arthroplasty. A qualitative and systematic review of the literature
    Olivier Ethgen
    WHO Collaborating Center for Public Health Aspects of Osteoarticular Diseases, Department of Public Health, Epidemiology, and Health Economics, University of Liege, Belgium, Liege, Belgium
    J Bone Joint Surg Am 86:963-74. 2004
    ..The objective of this study was to review the literature regarding the outcomes of total hip and knee arthroplasties as evaluated by health-related quality-of-life instruments...
  3. ncbi Registration completeness in the Norwegian Arthroplasty Register
    Birgitte Espehaug
    The Norwegian Arthroplasty Register, Department of Orthopedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 77:49-56. 2006
    ..A high degree of registration completeness is necessary in order to obtain unbiased and accurate register-based study results. We investigated the completeness of registration in the national Norwegian Arthroplasty Register (NAR)...
  4. ncbi The Norwegian Arthroplasty Register: 11 years and 73,000 arthroplasties
    L I Havelin
    Department of Orthopaedic Surgery, Haukeland University Hospital, Norway
    Acta Orthop Scand 71:337-53. 2000
    ..Since the practice of using undocumented implants has not changed, the register will continue to survey these implants. We plan to assess the mid- and long-term results of implants that have so far had good short-term results...
  5. pmc Uncemented and cemented primary total hip arthroplasty in the Swedish Hip Arthroplasty Register
    Nils P Hailer
    Department of Orthopaedics, Institute of Surgical Sciences, Uppsala University Hospital, Uppsala, Sweden
    Acta Orthop 81:34-41. 2010
    ..We therefore analyzed implant survival of cemented and uncemented THA, and whether the modes of failure differ between the two methods of fixation...
  6. pmc The epidemiology of revision total knee arthroplasty in the United States
    Kevin J Bozic
    Department of Orthopaedic Surgery and Philip R Lee Institute for Health Policy Studies, University of California, San Francisco, 500 Parnassus Ave, MU320W, San Francisco, CA 94143 0728, USA
    Clin Orthop Relat Res 468:45-51. 2010
    ..1 days, and the average total charges were $49,360. However, average LOS, average charges, and procedure frequencies varied considerably by census region, hospital type, and procedure performed...
  7. ncbi Prevalence of primary and revision total hip and knee arthroplasty in the United States from 1990 through 2002
    Steven Kurtz
    Exponent Inc, 3401 Market Street, Suite 300, Philadelphia, PA 19104, USA
    J Bone Joint Surg Am 87:1487-97. 2005
    ....
  8. ncbi More re-operations after uncemented than cemented hemiarthroplasty used in the treatment of displaced fractures of the femoral neck: an observational study of 11,116 hemiarthroplasties from a national register
    J E Gjertsen
    Haukeland University Hospital, Department of Orthopaedic Surgery, N 5021 Bergen, Norway
    J Bone Joint Surg Br 94:1113-9. 2012
    ..However, in a time-dependent analysis, the HRR for re-operation in both groups increased as follow-up increased. This study showed that the risk for revision was higher for uncemented than for cemented hemiarthroplasties...
  9. pmc The Nordic Arthroplasty Register Association: a unique collaboration between 3 national hip arthroplasty registries with 280,201 THRs
    Leif I Havelin
    The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 80:393-401. 2009
    ..In addition, we plan to study results in patient groups in which the numbers are too small to be studied in the individual countries...
  10. pmc Patient characteristics affecting the prognosis of total hip and knee joint arthroplasty: a systematic review
    Pasqualina L Santaguida
    Evidence Based Practice Centre, Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario
    Can J Surg 51:428-36. 2008
    ..This study addresses how patient characteristics influence the outcomes of hip and knee arthroplasty in patients with osteoarthritis...
  11. ncbi Pseudotumours associated with metal-on-metal hip resurfacings
    H Pandit
    Nuffield Orthopaedic Centre, Oxford, England
    J Bone Joint Surg Br 90:847-51. 2008
    ..We are concerned that with time the incidence of these pseudotumours may increase. Further investigation is required to define their cause...
  12. ncbi The epidemiology of revision total hip arthroplasty in the United States
    Kevin J Bozic
    Department of Orthopaedic Surgery and Philip R Lee Institute for Health Policy Studies, University of California, San Francisco, 500 Parnassus Avenue, MU 320W, San Francisco, CA 94143 0278, USA
    J Bone Joint Surg Am 91:128-33. 2009
    ....
  13. ncbi Hemiarthroplasty of the hip with and without cement: a randomized clinical trial
    Fraser Taylor
    Auckland City Hospital, Private Bag 92 024, Auckland Mail Centre, Auckland 1142, New Zealand
    J Bone Joint Surg Am 94:577-83. 2012
    ..The primary hypothesis of this study was that use of cement would provide better visual analog pain scores following this procedure in an elderly patient population...
  14. pmc Higher risk of reoperation for bipolar and uncemented hemiarthroplasty
    Olof Leonardsson
    Department of Orthopaedics, Lund University, Skane University Hospital, Malmo, Sweden
    Acta Orthop 83:459-66. 2012
    ..In this prospective observational study, we wanted to identify risk factors for reoperation in modular hemiarthroplasties and to evaluate mortality in this patient group.
  15. ncbi Early failure of metal-on-metal bearings in hip resurfacing and large-diameter total hip replacement: A consequence of excess wear
    D J Langton
    North Tees and Hartlepool NHS Trust, Stockton on Tees and Centre for Rehabilitation, Newcastle University, Newcastle upon Tyne, England
    J Bone Joint Surg Br 92:38-46. 2010
    ..Surgeons must consider implant design, expected component size and acetabular component positioning in order to reduce early failures when performing large-bearing metal-on-metal hip resurfacing and replacement...
  16. ncbi Antibiotic prophylaxis in total hip arthroplasty: effects of antibiotic prophylaxis systemically and in bone cement on the revision rate of 22,170 primary hip replacements followed 0-14 years in the Norwegian Arthroplasty Register
    Lars B Engesaeter
    The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop Scand 74:644-51. 2003
    ..This observational study shows that the best results were recorded when antibiotic prophylaxis was given both systemically and in the bone cement, and if the systemic antibiotic was given 4 times on the day of surgery...
  17. ncbi The Oxford hip scores for primary and revision hip replacement
    R E Field
    Epson and St Helier Hospital NHS Trust, Carshalton, Surrey SM5 1AA, UK
    J Bone Joint Surg Br 87:618-22. 2005
    ..Awareness of the influence of these factors should assist surgeons to provide balanced advice...
  18. ncbi Total hip arthroplasty revision due to infection: a cost analysis approach
    S Klouche
    Department of bone surgery and traumatology, Diaconesses Croix Saint Simon Hospital Group, 125, rue d Avron, 75020 Paris, France klouche
    Orthop Traumatol Surg Res 96:124-32. 2010
    ..The aim of this retrospective study was to determine the cost of revision of infected THA and to compare these costs to those of primary THA and revision of non-infected THA...
  19. ncbi Risk of revision of a total hip replacement in patients with diabetes mellitus: a population-based follow up study
    A B Pedersen
    Department of Clinical Epidemiology, Aarhus University Hospital, Olof Palmes Alle 43 45, 8200, Aarhus N, Denmark
    J Bone Joint Surg Br 92:929-34. 2010
    ..39 to 3.98)). Patients and surgeons should be aware of the relatively elevated risk of revision due to deep infection following THR in diabetes particularly in those with insufficient control of their glucose level...
  20. pmc Competing risks survival analysis applied to data from the Australian Orthopaedic Association National Joint Replacement Registry
    Marianne H Gillam
    School of Population Health and Clinical Practice, University of Adelaide, Adelaide, Australia
    Acta Orthop 81:548-55. 2010
    ..In the presence of a competing risk such as death, KM is known to overestimate the probability of revision. We investigated the degree to which the risk of revision is overestimated in registry data...
  21. pmc Risk factors for revision after shoulder arthroplasty: 1,825 shoulder arthroplasties from the Norwegian Arthroplasty Register
    Bjørg Tilde S Fevang
    Department of Rheumatology and The Norwegian Arthroplasty Register, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 80:83-91. 2009
    ..We describe the results of shoulder replacement in the Norwegian population (of 4.7 million) during a 12-year period. Trends in the use of shoulder arthroplasty during the study period were also investigated...
  22. ncbi Birmingham hip resurfacing: a minimum follow-up of ten years
    R B C Treacy
    Royal Orthopaedic Hospital, Bristol Road South, Northfield, Birmingham B31 2AP, UK
    J Bone Joint Surg Br 93:27-33. 2011
    ....
  23. ncbi A New Zealand national joint registry review of 202 total ankle replacements followed for up to 6 years
    Anton H Hosman
    Department of Orthopedic Surgery and Musculoskeletal Medicine, Christchurch School of Medicine and Health Sciences, University of Otago, Christchurch, New Zealand
    Acta Orthop 78:584-91. 2007
    ..The aim of this study was to document and evaluate the early results of a nationwide series of total ankle replacements (TARs) performed using second- and third-generation implants...
  24. pmc Increasing risk of revision due to deep infection after hip arthroplasty
    Håvard Dale
    The Norwegian Arthroplasty Register, Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop 80:639-45. 2009
    ..We assessed the risk of revision due to deep infection for primary THAs reported to the Norwegian Arthroplasty Register (NAR) over the period 1987-2007...
  25. ncbi Femoral head size is a risk factor for total hip luxation: a study of 42,987 primary hip arthroplasties from the Norwegian Arthroplasty Register
    Sven Byström
    Department of Orthopaedic Surgery, Haukeland University Hospital, Bergen, Norway
    Acta Orthop Scand 74:514-24. 2003
    ..A posterior approach increased the risk of revision more than a lateral one (FRR 1.9, 95% CI 1.4-2.5). Gender, trochanteric osteotomy and duration of the operation did not affect the results...
  26. ncbi Central compartment reoperation for recurrent/persistent differentiated thyroid cancer: patterns of recurrence, morbidity, and prediction of postoperative hypocalcemia
    Jong Lyel Roh
    Department of Otolaryngology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea
    Ann Surg Oncol 18:1312-8. 2011
    Incidence rates of hypoparathyroidism and vocal cord paralysis are high following central compartment reoperation, but few prospective studies have assessed morbidities and factors predictive of hypocalcemia after reoperation...
  27. ncbi Complications requiring reoperation after gastrectomy for gastric cancer: 17 years experience in a single institute
    Sung Jin Oh
    Department of Surgery, College of Medicine, Yonsei University, 134 Shinchon dong Seodaemun gu, Seoul 120 752, South Korea
    J Gastrointest Surg 13:239-45. 2009
    Morbidity and mortality rates following gastric cancer surgery are still high. The present study documented complications requiring reoperation after gastrectomy for gastric cancer and described surgical management for each complication.
  28. ncbi Outcome of short proximal femoral nail antirotation and dynamic hip screw for fixation of unstable trochanteric fractures. A randomised prospective comparative trial
    Bhavuk Garg
    Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India
    Hip Int 21:531-6. 2011
    ..The primary outcome measure was reoperation within the first postoperative year and mortality at the end of one year...
  29. pmc Hip resurfacing arthroplasty: short-term survivorship of 4,401 hips from the Finnish Arthroplasty Register
    Matti Seppänen
    Department of Orthopaedics and Traumatology, Turku University Hospital, Turku, Finland
    Acta Orthop 83:207-13. 2012
    ..We analyzed the short-term survival of 4,401 HRAs in the Finnish Arthroplasty Register...
  30. ncbi Systematic review of cemented versus uncemented hemiarthroplasty for displaced femoral neck fractures in older patients
    Xiangping Luo
    Department of Orthopedic Surgery, The People s Hospital of Leiyang, Hunan, China
    Arch Orthop Trauma Surg 132:455-63. 2012
    ..that there was no significant difference between cemented and uncemented group with regard to the mortality, reoperation rates and postoperational complications...
  31. ncbi Intraoperative neuromonitoring does not reduce the incidence of recurrent laryngeal nerve palsy in thyroid reoperations: results of a retrospective comparative analysis
    Piero F Alesina
    Klinik für Chirurgie und Zentrum für Minimal Invasive Chirurgie, Kliniken Essen Mitte, Akademisches Lehrkrankenhaus der Universität Duisburg Essen, Henricistrasse 92, 45136 Essen, Germany
    World J Surg 36:1348-53. 2012
    ..The present study is a retrospective analysis of the experience with completion thyroidectomy with and without neuromonitoring in a referral center...
  32. pmc Reoperation rates after breast conserving surgery for breast cancer among women in England: retrospective study of hospital episode statistics
    R Jeevan
    Clinical Effectiveness Unit, Royal College of Surgeons of England, London WC2A 3PE, UK
    BMJ 345:e4505. 2012
    To examine whether rate of reoperation after breast conserving surgery is associated with patients' characteristics and investigate whether reoperation rates vary among English NHS trusts.
  33. ncbi Different surgical techniques to reduce post-operative adhesion formation: a systematic review and meta-analysis
    R P G Ten Broek
    Department of Surgery, Radboud University Nijmegen Medical Centre, HB Nijmegen, The Netherlands
    Hum Reprod Update 19:12-25. 2013
    ..surgery and the leading cause of small bowel obstruction, acquired infertility and inadvertent organ injury at reoperation. Using a 'good surgical technique' is advocated as a first step in preventing adhesions...
  34. ncbi Variability in reexcision following breast conservation surgery
    Laurence E McCahill
    Richard J Lacks Cancer Center, Van Andel Research Institute, and Department of Surgery, Michigan State University, Grand Rapids, MI 49503, USA
    JAMA 307:467-75. 2012
    ..Partial mastectomy is the most commonly performed procedure for invasive breast cancer and often requires reexcision. Variability in reexcision might be reflective of the quality of care...
  35. ncbi Spinal cord stimulation versus reoperation for failed back surgery syndrome: a cost effectiveness and cost utility analysis based on a randomized, controlled trial
    Richard B North
    Department of Neurosurgery, The Johns Hopkins University, Baltimore, Maryland 21287, USA
    Neurosurgery 61:361-8; discussion 368-9. 2007
    We analyzed the cost-effectiveness and cost-utility of treating failed back-surgery syndrome using spinal cord stimulation (SCS) versus reoperation.
  36. pmc Risk factors for revision due to infection after primary total hip arthroplasty. A population-based study of 80,756 primary procedures in the Danish Hip Arthroplasty Registry
    Alma B Pedersen
    Department of Clinical Epidemiology, Aarhus University Hospital, Arhus, Denmark
    Acta Orthop 81:542-7. 2010
    ..We therefore studied patient- and surgery-related risk factors for revision due to infection after primary THA in a population-based setting...
  37. ncbi Infection of the surgical site after arthroplasty of the hip
    S Ridgeway
    Health Protection Agency, 61 Colindale Avenue, London NW9 5EQ, UK
    J Bone Joint Surg Br 87:844-50. 2005
    ..MRSA was the most common pathogen to cause SSI in hip arthroplasty, especially in patients undergoing hemiarthroplasty, but coagulase-negative Staph. aureus may be more important in deep infections involving the joint...
  38. ncbi The Finnish Arthroplasty Register: report of the hip register
    T J Puolakka
    Department of Surgery, Tampere University Hospital, Finland
    Acta Orthop Scand 72:433-41. 2001
    ..With the civic registration number, one can link and match data files. For example, with use of the Finnish Cancer Register, we found no increase in the risk of cancer after a THA...
  39. ncbi Grammont inverted total shoulder arthroplasty in the treatment of glenohumeral osteoarthritis with massive rupture of the cuff. Results of a multicentre study of 80 shoulders
    F Sirveaux
    Clinic of Traumatology and Orthopaedics, Nancy, France
    J Bone Joint Surg Br 86:388-95. 2004
    ..It should be considered in the treatment of osteoarthritis with a massive tear of the cuff but should be reserved for elderly patients...
  40. ncbi Total joint arthroplasties: current concepts of patient outcomes after surgery
    C Allyson Jones
    Department of Physical Therapy, Faculty of Rehabilitation Medicine, University of Alberta, 2 50 Corbett Hall, Edmonton, Alberta T6G 2G4, Canada
    Rheum Dis Clin North Am 33:71-86. 2007
    ..Mounting evidence suggests that no single patient-related or perioperative factor clearly predicts the amount of pain relief or functional improvement that will occur following total hip or knee arthroplasty...
  41. ncbi Integrity of the lateral femoral wall in intertrochanteric hip fractures: an important predictor of a reoperation
    Henrik Palm
    Department of Orthopaedic Surgery, Copenhagen University Hospital of Hvidovre, Hvidovre, Denmark
    J Bone Joint Surg Am 89:470-5. 2007
    ..We investigated the importance of an intact lateral femoral wall as a factor in postoperative fracture displacement after fixation with a sliding compression hip screw...
  42. ncbi Reoperation rates following lumbar spine surgery and the influence of spinal fusion procedures
    Brook I Martin
    Department of Medicine, University of Washington, Seattle, WA, USA
    Spine (Phila Pa 1976) 32:382-7. 2007
    ..Retrospective cohort study using a hospital discharge registry of all nonfederal acute care hospitals in Washington state...
  43. ncbi What is the benefit of introducing new hip and knee prostheses?
    Rajan Anand
    Discipline of Public Health, University of Adelaide, MDP DX650, 511 Australia SA 5005
    J Bone Joint Surg Am 93:51-4. 2011
    ..The underlying purpose of the introduction of new devices is to improve patient outcomes. This study was undertaken to determine how many new prostheses were associated with improved patient outcomes...
  44. pmc Arch debranching versus elephant trunk procedures for hybrid repair of thoracic aortic pathologies
    Constance W Lee
    Division of Vascular Surgery and Endovascular Therapy, University of Florida College of Medicine, Gainesville, Florida, USA
    Ann Thorac Surg 91:465-71. 2011
    ..We compared outcomes of arch debranching (AD) and elephant trunk (ET) techniques when used with thoracic endovascular aortic repair...
  45. ncbi Periprosthetic infection: what are the diagnostic challenges?
    Javad Parvizi
    J Bone Joint Surg Am 88:138-47. 2006
  46. pmc Two-stage total hip arthroplasty: how often does it control methicillin-resistant infection?
    Fay Leung
    Department of Orthopaedics, University of British Columbia, 3114 910 West 10th Avenue, Vancouver, BC V5Z 4E3, Canada
    Clin Orthop Relat Res 469:1009-15. 2011
    ..Methicillin-resistant hip infections are increasingly common. Reports of the surgical management of these patients using two-stage THA show variable control of infection, but all reports used static spacers...
  47. ncbi Long-term outcomes of laparoscopic adjustable gastric banding and laparoscopic Roux-en-Y gastric bypass in the United States
    Hadar Spivak
    HS Laparoscopy, Weight Loss Surgery Program, Park Plaza Hospital, 1313 Hermann Drive, 1200 Binz Suite 930, Houston, TX 77004, USA
    Surg Endosc 26:1909-19. 2012
    ..Although laparoscopic adjustable gastric banding (LAGB) and laparoscopic Roux-en-Y gastric bypass (LRYGB) are the most common bariatric procedures performed in the past decade, little is known about their long-term (>5 years) outcomes...
  48. pmc Kaiser Permanente National Total Joint Replacement Registry: aligning operations with information technology
    Elizabeth W Paxton
    Surgical Outcomes and Analysis Unit of Clinical Analysis, Kaiser Permanente, 3033 Bunker Hill Street, San Diego, CA 92109, USA
    Clin Orthop Relat Res 468:2646-63. 2010
    ....
  49. ncbi Optimal acetabular orientation for hip resurfacing
    G Grammatopoulos
    Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences University of Oxford, Botnar Research Centre, Nuffield Orthopaedic Centre, Oxford OX3 7LD, UK
    J Bone Joint Surg Br 92:1072-8. 2010
    ..Because of differences between the radiographic and the operative angles, this may be best achieved by aiming for an inclination of 40 degrees and an anteversion of 25 degrees...
  50. pmc Predictors of moderate-severe functional limitation 2 and 5 years after revision total knee arthroplasty
    Jasvinder A Singh
    Department of Health Sciences Research, Mayo Clinic School of Medicine, Rochester, Minnesota, USA
    J Arthroplasty 25:1091-5, 1095.e1-4. 2010
    ..At both 2 and 5 years of follow-up, BMI of 40 or higher, higher Deyo-Charlson score, female sex, and age greater than 80 years, each significantly predicted higher odds of moderate-severe overall activity limitation...
  51. ncbi Off-label use of bone morphogenetic proteins in the United States using administrative data
    Kevin L Ong
    Exponent Inc, Philadelphia, PA 19104, USA
    Spine (Phila Pa 1976) 35:1794-800. 2010
    ..Epidemiological study using national administrative data...
  52. ncbi An intraoperatively moulded PMMA prostheses like spacer for two-stage revision of infected total knee arthroplasty
    Sandro Kohl
    Department of Orthopaedic Surgery, Inselspital, University of Bern, Switzerland
    Knee 18:464-9. 2011
    ..The use of this spacer is a time sparing, cheap and convenient option in 2-stage TKA revision...
  53. pmc Can implant retention be recommended for treatment of infected TKA?
    Ho Rim Choi
    Harris Orthopedic Laboratory, Department of Orthopedic Surgery, Massachusetts General Hospital, 55 Fruit Street, GRJ 1126, Boston, MA 02114, USA
    Clin Orthop Relat Res 469:961-9. 2011
    ..Retention treatment is reportedly associated with lower infection control rates than two-stage revision. However, the studies on which this presumption are based depend on comparisons of historical rather than concurrent controls...
  54. pmc Late complications and survival of endoprosthetic reconstruction after resection of bone tumors
    Ahmad Shehadeh
    Washington Cancer Institute at Washington Hospital Center, Washington, DC, USA
    Clin Orthop Relat Res 468:2885-95. 2010
    ..While complications following massive endoprosthetic reconstruction have been previously described, the incidence and effects of these complications over extended periods of time have not been well characterized in large series...
  55. pmc Outcome of prosthesis exchange for infected knee arthroplasty: the effect of treatment approach
    Esa Jämsen
    Medical School, University of Tampere, Tampere, Finland
    Acta Orthop 80:67-77. 2009
    ..The purpose of this literature review is to compare the clinical outcome achieved with one-stage revision and two-stage revision with different types of spacers...
  56. ncbi Monoblock hemiarthroplasties for femoral neck fractures--a part of orthopaedic history? Analysis of national registration of hemiarthroplasties 2005-2009
    Cecilia Rogmark
    Department of Orthopaedic Surgery, Skane University Hospital, Malmo, Sweden
    Injury 43:946-9. 2012
    ..Cemented Thompson(®) or ETS(®) implants could still be suitable for the oldest, low-activity patients. To finally decide if there is a place for them, patient-reported outcome must be analysed as well...
  57. pmc Minimizing dynamic knee spacer complications in infected revision arthroplasty
    Aaron J Johnson
    Center for Joint Preservation and Replacement, Rubin Institute for Advanced Orthopedics, Sinai Hospital of Baltimore, 2401 West Belvedere Avenue, Baltimore, MD 21215, USA
    Clin Orthop Relat Res 470:220-7. 2012
    ..However, because of several dynamic spacer problems noted at our institution, we wanted to assess their associated failures, reinfection rates, and functionality...
  58. ncbi Total hip arthroplasty: to cement or not to cement the acetabular socket? A critical review of the literature
    N D Clement
    Department of Orthopaedics and Trauma, Royal Infirmary of Edinburgh, Little France, Edinburgh, UK
    Arch Orthop Trauma Surg 132:411-27. 2012
    ....
  59. pmc Durable infection control and function with the PROSTALAC spacer in two-stage revision for infected knee arthroplasty
    Christopher R Gooding
    Division of Lower Limb Reconstruction and Oncology, Department of Orthopaedics, University of British Columbia, Vancouver, BC, Canada
    Clin Orthop Relat Res 469:985-93. 2011
    ..The PROSTALAC knee spacer is an antibiotic-loaded cement articulating spacer that allows some movement of the knee between stages. Whether motion enhances long-term function is unknown...
  60. pmc Validity of frozen sections for analysis of periprosthetic loosening membranes
    Stephan W Tohtz
    Center for Musculoskeletal Surgery, Charite Universitatsmedizin Berlin, Chariteplatz 1, 10117 Berlin, Germany
    Clin Orthop Relat Res 468:762-8. 2010
    ..6%, specificity 100%, and accuracy 96.2%. Our data support a recommendation for use of intraoperative frozen sections for diagnosis of septic versus aseptic loosening in revision hip surgery...
  61. pmc Arthroplasty options in femoral-neck fracture: answers from the national registries
    Arun Kannan
    University of Minnesota, Minneapolis, MN, USA
    Int Orthop 36:1-8. 2012
    ..Clinical trials and systematic reviews of such trials have not provided a convincing answer to this question...
  62. ncbi Total hip replacement and hemiarthroplasty in mobile, independent patients with a displaced intracapsular fracture of the femoral neck: a seven- to ten-year follow-up report of a prospective randomised controlled trial
    P P Avery
    North Bristol NHS Trust, Avon Orthopaedic Centre, Bristol BS10 5NB, UK
    J Bone Joint Surg Br 93:1045-8. 2011
    ..There was lower mortality (p = 0.013) and a trend towards superior function in patients with a total hip replacement in the medium term...
  63. ncbi Management of gastrointestinal leaks after surgery for clinically severe obesity
    Charalambos Spyropoulos
    Department of Surgery, University Hospital of Patras, Rion, Greece
    Surg Obes Relat Dis 8:609-15. 2012
    ..Our objective was to describe the clinical presentation and treatment outcomes in patients who developed postoperative leaks at a university hospital bariatric referral center...
  64. ncbi Total knee arthroplasty in obese patients: a comparison with a matched control group
    Jared R H Foran
    Department of Orthopaedic Surgery, The Good Samaritan Hospital, Arthritis Division of The Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Arthroplasty 19:817-24. 2004
    ..This may occur because of increasing stress at the bone-prosthesis interface, whereas increased activity levels in the nonobese patients may adversely affect the longevity of the polyethylene insert...
  65. pmc Selection criteria for repeat hepatectomy in patients with recurrent hepatocellular carcinoma
    Masami Minagawa
    Department of Hepato Biliary Pancreatic Surgery, Graduate School of Medicine, University of Tokyo, Japan
    Ann Surg 238:703-10. 2003
    ..The purpose of this study was to evaluate prognostic factors in patients with recurrence after curative resection of hepatocellular carcinoma (HCC) and to identify selection criteria for repeat resection...
  66. ncbi Systematic review of dynamic graciloplasty in the treatment of faecal incontinence
    A E Chapman
    Australian Safety and Efficacy Register of New Interventional Procedures Surgical, Royal Australasian College of Surgeons, Adelaide, South Australia, Australia
    Br J Surg 89:138-53. 2002
    ..The aim of this systematic review was to compare the safety and efficacy of dynamic graciloplasty with colostomy for the treatment of faecal incontinence...
  67. pmc A modular cementless stem vs. cemented long-stem prostheses in revision surgery of the hip: a population-based study from the Swedish Hip Arthroplasty Register
    Rudiger J Weiss
    Department of Molecular Medicine and Surgery, Section of Orthopaedics and Sports Medicine, Karolinska Institutet, Karolinska University Hospital, Stockholm, Sweden
    Acta Orthop 82:136-42. 2011
    ..In this paper, we review risk factors for the outcome of the Link MP stem and report implant survival compared to conventional cemented long-stem hip revision arthroplasties...
  68. pmc Alumina-on-alumina hip arthroplasty in patients younger than 30 years old
    R Nizard
    Department of Orthopaedic Surgery, Lariboisiere Hospital, 2, rue A Paré, 75010 Paris, France
    Clin Orthop Relat Res 466:317-23. 2008
    ..The main limiting factor in this series was the fixation of the acetabular component. However, improvements in the design and in the mode of fixation of this component should enhance long-term results...
  69. pmc Risk of subsequent revision after primary and revision total joint arthroplasty
    Kevin L Ong
    Exponent, Inc, 3401 Market Street, Suite 300, Philadelphia, PA 19104, USA
    Clin Orthop Relat Res 468:3070-6. 2010
    ..Understanding the relative risk of rerevision and risk factors can help identify patients at high risk who may require closer postsurgical care...
  70. pmc Polymicrobial prosthetic joint infections: risk factors and outcome
    Camelia E Marculescu
    Division of Infectious Diseases, Medical University of South Carolina, 100 Doughty Street, Suite 210, BA IOP South, PO Box 250752, Charleston, SC 29425, USA
    Clin Orthop Relat Res 466:1397-404. 2008
    ..We found the following factors associated with polymicrobial prosthetic joint infections: the presence of a soft tissue defect/wound dehiscence (odds ratio, 5.9), drainage (odds ratio, 5.0), and age 65 years or older (odds ratio, 2.8)...
  71. ncbi Survival of metal-on-metal hip resurfacing arthroplasty: a systematic review of the literature
    W van der Weegen
    Department of Orthopaedic Surgery, St Anna Hospital, Geldrop, The Netherlands
    J Bone Joint Surg Br 93:298-306. 2011
    ..None of the hip resurfacing arthroplasty implants used to date met the full ten-year NICE benchmark of survival. A total of 13 studies showed satisfactory survival compared with the three-year NICE benchmark...
  72. ncbi Cementless modular hip arthroplasty as a salvage operation for failed internal fixation of trochanteric fractures in elderly patients
    Jean Michel Laffosse
    Service de chirurgie orthopédique et de traumatologie, CHU Rangueil et CHU Purpan, Toulouse, France
    Acta Orthop Belg 73:729-36. 2007
    ..Primary arthroplasty with such an implant could be considered in selected cases such as markedly unstable fractures and in osteoporotic elderly patients...
  73. ncbi The risk of revision after primary total hip arthroplasty among statin users: a nationwide population-based nested case-control study
    Theis M Thillemann
    Department of Orthopedics, Aarhus University Hospital, Aarhus N, Denmark
    J Bone Joint Surg Am 92:1063-72. 2010
    ..The association between statin use and the risk of revision after primary total hip arthroplasty has not been examined...
  74. pmc Management of renal tumors by image-guided radiofrequency ablation: experience in 105 tumors
    David J Breen
    Department of Radiology, Southampton University Hospitals NHS Trust, Tremona Road, Southampton, Hampshire SO16 6YD, UK
    Cardiovasc Intervent Radiol 30:936-42. 2007
    ..In this article we present our experience with radiofrequency ablation (RFA) in the treatment of 105 renal tumors...
  75. ncbi Long-term outcomes of needle revision of trabeculectomy blebs with mitomycin C and 5-fluorouracil: a comparative safety and efficacy report
    Nitin Anand
    Department of Ophthalmology, Calderdale and Huddersfield NHS Trust, Huddersfield Royal Infirmary, Huddersfield
    J Glaucoma 18:513-20. 2009
    ..To report the long-term comparative outcomes for needle revision with 5-fluorouracil (5-FU) and mitomycin C (MMC) of failed trabeculectomy blebs...
  76. ncbi Ten-year survival of second kidney transplants: impact of immunologic factors and renal function at 12 months
    Stephanie Coupel
    Institut de Transplantation et de Recherche en Transplantation and INSERM U437, Immunointervention en Allo et Xénotransplantations, Nantes, France
    Kidney Int 64:674-80. 2003
    ..The aim of the present study was to assess long-term survival of cadaveric second kidney allografts performed in our center and to determine risk factors predictive of long-term graft outcome...
  77. ncbi A comparison of hemiarthroplasty with total hip replacement for displaced intracapsular fracture of the femoral neck: a randomised controlled multicentre trial in patients aged 70 years and over
    M P J van den Bekerom
    Department of Orthopaedic Surgery, Academic Medical Center, Amsterdam, The Netherlands
    J Bone Joint Surg Br 92:1422-8. 2010
    ..002), we do not recommend THR as the treatment of choice in patients aged ≥ 70 years with a fracture of the femoral neck in the absence of advanced radiological osteoarthritis or rheumatoid arthritis of the hip...
  78. pmc What works best, a cemented or cementless primary total hip arthroplasty?: minimum 17-year followup of a randomized controlled trial
    Kristoff Corten
    London Health Sciences Centre, University Campus, 339 Windermere Road, London, ON N6A 5A5, Canada
    Clin Orthop Relat Res 469:209-17. 2011
    ..Total hip arthroplasty (THA) has been associated with high survival rates, but debate remains concerning the best fixation mode of THA...
  79. pmc Can this prosthesis be saved?: implant salvage attempts in infected primary TKA
    Jeremy Gardner
    Department of Orthopaedic Surgery, University of Minnesota Medical School, Minneapolis, MN, USA
    Clin Orthop Relat Res 469:970-6. 2011
    ..We sought to identify factors that would predict control of infection after ODPE...
  80. ncbi Comparison of one and two-stage revision of total hip arthroplasty complicated by infection: a Markov expected-utility decision analysis
    Christopher F Wolf
    University of Washington, Seattle, Washington, USA
    J Bone Joint Surg Am 93:631-9. 2011
    ..Using a decision analysis, we compared single-stage and two-stage revisions to determine which treatment modality resulted in greater quality-adjusted life years (QALYs)...
  81. ncbi Long-term results of the ABG-1 hydroxyapatite coated total hip arthroplasty: analysis of 111 cases with a minimum follow-up of 10 years
    R Bidar
    Department of Orthopaedics and Traumatology, Carémeau Teaching Hospital Center, place du Pr Robert Debré, 30029 Nimes Cedex 9, France
    Orthop Traumatol Surg Res 95:579-87. 2009
    ....
  82. ncbi Cost effectiveness of revision total knee arthroplasty
    Alexander W R Burns
    London Health Sciences Centre, University of Western Ontario, London, Ontario, Canada
    Clin Orthop Relat Res 446:29-33. 2006
    ..Level of Evidence: Prognostic study, level II-1 (prospective study). See Guidelines for Authors for complete description of levels of evidence...
  83. pmc Trabecular Metal cups for acetabular defects with 50% or less host bone contact
    Dror Lakstein
    Orthopedic Department, Division of Arthroplasty, Mount Sinai Hospital, 600 University Avenue, Suite 476A, Toronto, ON, M5G 1X5, Canada
    Clin Orthop Relat Res 467:2318-24. 2009
    ..The data suggest treatment of cavitary defects with less than 50% host bone contact using Trabecular Metal cups, without structural support by augments or structural bone grafts, is a reasonable option...
  84. ncbi Total knee arthroplasty survivorship in the United States Medicare population: effect of hospital and surgeon procedure volume
    Michael Manley
    Homer Stryker Center for Orthopaedic Education and Research, Mahwah, New Jersey 07430, USA
    J Arthroplasty 24:1061-7. 2009
    ..52, respectively). Surgeon volume was not significantly correlated with implant survivorship. Our findings suggest that TKA patients at low-volume hospitals have a greater revision risk at medium-term follow-up, but not in the short term...
  85. ncbi Hip arthroplasty for salvage of failed treatment of intertrochanteric hip fractures
    George J Haidukewych
    Mayo Clinic, Rochester, Minnesota 55905, USA
    J Bone Joint Surg Am 85:899-904. 2003
    ..The purpose of the present study was to evaluate the results and complications of hip arthroplasty performed as a salvage procedure after the failed treatment of an intertrochanteric hip fracture...
  86. ncbi The optimal surgical treatment for primary hyperparathyroidism in MEN1 patients: a systematic review
    Jennifer M J Schreinemakers
    Department of Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3584CX, Utrecht, The Netherlands
    World J Surg 35:1993-2005. 2011
    ..The optimal surgical approach for patients with primary hyperparathyroidism (pHPT) and multiple endocrine neoplasia 1 (MEN1) is controversial. We sought to determine the optimal type of surgery for pHPT in MEN1...
  87. ncbi Birmingham hip resurfacing: the prevalence of failure
    A D Carrothers
    Robert Jones and Agnes Hunt Orthopaedic Hospital, Gobowen, Oswestry SY10 7AG, UK
    J Bone Joint Surg Br 92:1344-50. 2010
    ..5 years, 0.02 to 11.0). There was a significantly shorter time to failure in men (mean 2.1 years, 0.4 to 8.7) compared with women (mean 3.6 years, 0.003 to 11.0) (p < 0.001)...
  88. ncbi Primary total hip arthroplasty with a proximally porous-coated femoral stem
    Raj K Sinha
    University of Pittsburgh Medical Center, Pennsylvania, USA
    J Bone Joint Surg Am 86:1254-61. 2004
    ..The purpose of the present report was to examine the five to ten-year results associated with the use of a so-called second-generation circumferentially proximally porous-coated titanium-alloy stem...
  89. ncbi Needling revision of trabeculectomies bleb morphology and long-term survival
    Alan P Rotchford
    Department of Ophthalmology, Queen s Medical Centre, Nottingham University Hospitals National Health Service Trust, Nottingham, United Kingdom
    Ophthalmology 115:1148-1153.e4. 2008
    ..To assess the long-term success rate and to determine factors that predict survival after 5-fluorouracil-augmented needling revision of poorly functioning trabeculectomy blebs...
  90. pmc Surgical reintervention after failed antireflux surgery: a systematic review of the literature
    Edgar J B Furnee
    Department of Surgery, H P G04 228, University Medical Centre Utrecht, P O Box 85500, 3508 GA, Utrecht, The Netherlands
    J Gastrointest Surg 13:1539-49. 2009
    ..Studies reporting on redo surgery, however, are usually much smaller than those of primary surgery. The aim of this study was to summarize the currently available literature on redo antireflux surgery...
  91. ncbi Long-term outcomes of surgical and nonsurgical management of lumbar spinal stenosis: 8 to 10 year results from the maine lumbar spine study
    Steven J Atlas
    General Medicine Division and the Clinical Epidemiology Unit, Medical Services, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    Spine (Phila Pa 1976) 30:936-43. 2005
    ..A prospective observational cohort study...
  92. pmc Total ankle replacement: a population-based study of 515 cases from the Finnish Arthroplasty Register
    Eerik T Skyttä
    COXA Hospital for Joint Replacement, Tampere, Finland
    Acta Orthop 81:114-8. 2010
    ..We evaluated the survival of two TAR designs and factors associated with survival using data from the nationwide arthroplasty registry in Finland...
  93. pmc Total disc replacement compared to lumbar fusion: a randomised controlled trial with 2-year follow-up
    Svante Berg
    Stockholm Spine Center, Löwenströmska Hospital, 19489, Upplands Vasby, Sweden
    Eur Spine J 18:1512-9. 2009
    ..One year after surgery, TDR was superior to spinal fusion in clinical outcome, but this difference had diminished by 2 years, apart from (VAS for back pain and) numbers of pain-free. The long-term benefits have yet to be examined...
  94. ncbi Comparison of survival and cost-effectiveness between unicondylar arthroplasty and total knee arthroplasty in patients with primary osteoarthritis: a follow-up study of 50,493 knee replacements from the Finnish Arthroplasty Register
    Esa Koskinen
    Orton Orthopedic Hospital, Helsinki, Finland
    Acta Orthop 79:499-507. 2008
    ..We therefore compared the survival of UKA with that of TKA and conducted a cost-benefit analysis comparing UKA with TKA in patients with primary OA...
  95. ncbi Laparoscopic sleeve gastrectomy as an initial weight-loss procedure for high-risk patients with morbid obesity
    D Cottam
    Department of Surgery, University of Pittsburgh Medical Centre, Veterans Hospital, Pittsburgh, PA, USA
    Surg Endosc 20:859-63. 2006
    ..In an effort to achieve more favorable outcomes, we have employed a two-stage approach to such high-risk patients. This study evaluates our initial outcomes with this technique...
  96. ncbi Long-term outcomes following laparoscopically assisted versus open ileocolic resection for Crohn's disease
    E J Eshuis
    Departments of Surgery, Academic Medical Centre, Amsterdam, The Netherlands
    Br J Surg 97:563-8. 2010
    ..Long-term results of laparoscopically assisted versus open ileocolic resection for Crohn's disease were evaluated in a randomized trial...
  97. ncbi Preoperative thresholds for pulmonary valve replacement in patients with corrected tetralogy of Fallot using cardiovascular magnetic resonance
    Thomas Oosterhof
    Academic Medical Center, Department of Cardiology, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Circulation 116:545-51. 2007
    ..To facilitate the optimal timing of pulmonary valve replacement, we analyzed preoperative thresholds of right ventricular (RV) volumes above which no decrease or normalization of RV size takes place after surgery...
  98. ncbi The long-term outcome of high tibial osteotomy: a ten- to 20-year follow-up
    S Akizuki
    Department of Orthopaedic Surgery, Nagano Matsushiro General Hospital, 183 Matsushiro, Nagano City 381 1231, Japan
    J Bone Joint Surg Br 90:592-6. 2008
    ..5 kg/m(2) and range of movement < 100 degrees were risk factors predicting early failure. Although our long-term results were satisfactory, strict indications for osteotomy are required if long-term survival is required...
  99. ncbi Morbidity following central compartment reoperation for recurrent or persistent thyroid cancer
    Michael K Kim
    Fair Grounds Medical Center, Allentown, PA, USA
    Arch Otolaryngol Head Neck Surg 130:1214-6. 2004
    To determine the incidence of recurrent laryngeal nerve injury and hypoparathyroidism, we reviewed our experience with central compartment reoperation.
  100. ncbi Preoperative ultrasound-guided tattooing localization of recurrences after thyroidectomy: safety and effectiveness
    Tae Wook Kang
    Departments of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine, Kangnam Gu, Seoul, Republic of Korea
    Ann Surg Oncol 16:1655-9. 2009
    ..We assessed the safety and effectiveness of ultrasound-guided tattooing (US-tattoo) with a charcoal suspension for localizing nonpalpable cervical recurrences after thyroidectomy for thyroid cancer...
  101. pmc Follow-up of 11-16 years after modular fixed-bearing TKA
    D Parsch
    Department of Orthopaedic Surgery, University of Heidelberg, Heidelberg, Germany
    Int Orthop 33:431-5. 2009
    ..The mean Knee Society and function scores were 76 and 48 points, respectively. In this multi-surgeon series modular fixed-bearing TKA had good clinical and radiographic results with excellent long-term survivorship...

Research Grants59

  1. REDUCING LAPAROTOMY WOUND FAILURE
    Sufan Chien; Fiscal Year: 2013
    ..5 billion dollars without considering the loss of productivity. Reoperation is risky with a higher recurrence rate...
  2. Variation in the Safety of Back Pain-Related Surgery
    Sohail K Mirza; Fiscal Year: 2010
    ..We propose to use population-based rates of reoperation as a tool to study disparities in quality of care for back surgery...
  3. Engineered imaging nanoparticles for real-time detection of cancer in the tumor b
    W David Lee; Fiscal Year: 2013
    ..to remove cancer cells during surgery is a leading risk factor for local tumor recurrence and subsequent reoperation. Rates of secondary surgeries because of positive margins range between 10-50% depending on cancer type, grade ..
  4. Biomechanical Factors in Congenital Vascular Disease
    JESSICA WAGENSEIL; Fiscal Year: 2013
    ..Complications of COA and SVAS treatment include operative mortality, aneurysms and recoarctation requiring reoperation. In both COA and SVAS, elastic fiber fragmentation suggests that elasticity and mechanical properties of the ..
  5. Is impaired fracture healing in smokers related to CO exposure?
    John Wixted; Fiscal Year: 2013
    ..For severe injuries, such as open tibia fractures, reoperation rates exceed 60% in some series, and patient reported outcomes even after the fracture is healed remain ..
  6. Engineered imaging nanoparticle for realtime detection of cancer in the tumor bed
    W David Lee; Fiscal Year: 2011
    ..to remove cancer cells during surgery is a leading risk factor for local tumor recurrence and subsequent reoperation. For 35% of sarcoma patients, limb-sparing surgery supported by frozen sections, which only analyze a small ..
  7. Preventing Vein Graft Stenosis in Peripheral Vascular Surgery
    Michael Sobel; Fiscal Year: 2013
    ..Graft narrowing and scarring is a leading cause of reoperation, graft failure and limb loss, and yet the contributory factors are poorly understood...
  8. Exchangeable Heart Valve for Tissue Engineering Applications
    Ivan Vesely; Fiscal Year: 2007
    ..The issue that drives the decision for a mechanical or bioprosthetic valve is the risk of reoperation - prosthetic valves are intended to be implanted once and should last the life of the patient...
  9. Revision ACL Reconstructions: A Comparative Effectiveness Treatment Study
    Rick W Wright; Fiscal Year: 2012
    ..Specific Aim 1 will determine if graft choice predicts incidence of graft rerupture, reoperation, return to sports function and activity level 2 years post-surgery...
  10. Hip Fracture Evaluation Alternatives of Total Hip vs Hemi-arthroplasty (HEALTH)
    Thomas Einhorn; Fiscal Year: 2009
    ..Study: In patients over 50 years who have sustained a displaced femoral neck fracture, what is the rate of reoperation at 2 years when THA versus HA is used as the surgical treatment? We will also evaluate patient function and ..
  11. BACK PAIN OUTCOME ASSESSMENT TEAM
    Richard Deyo; Fiscal Year: 1991
    ..The frequency of mortality, readmission, reoperation and nursing home placement will assessed with Medicare data...
  12. 5-FLUOROURACIL & GLAUCOMA FILTERING SURGERY
    Dale Heuer; Fiscal Year: 1992
    ..Postoperative success and failure rates were determined by reoperation rates and by defined intraocular pressure (IOP) levels...
  13. 5-FLUOROURACIL & GLAUCOMA FILTERING SURGERY
    Richard Parrish; Fiscal Year: 1993
    ..Postoperative success and failure rates were determined by reoperation rates and by defined intraocular pressure (IOP) levels...
  14. FLUOROURACIL FILTERING SURGERY STUDY
    WALLACE ALWARD; Fiscal Year: 1992
    ..Postoperative success and failure rates were determined by reoperation rates and by defined intraocular pressure (IOP) levels...
  15. 5-FLUOROURACIL AND GLAUCOMA FILTERING SURGERY
    MICHAEL KASS; Fiscal Year: 1992
    ..Postoperative success and failure rates were determined by reoperation rates and by defined intraocular pressure (IOP) levels. Possible risks of 5-FU were monitored...
  16. REPRODUCTION AND SURVIVAL AFTER CARDIAC DEFECT REPAIR
    Cynthia Morris; Fiscal Year: 1991
    ..This study has two major objectives: 1) to determine mortality, morbidity (reoperation, arrhythmias, endocarditis), and disability after repair of CHD, and the major risk factors which predict these ..
  17. NIAMS Muiltidisciplinary Clinical Research Center in...
    Richard Deyo; Fiscal Year: 2006
    ..of interbody fusion cages; quantify the shift of spine surgery to the ambulatory setting; and determine if reoperation rates are increasing over time, as suggested in some earlier analyses. 4...
  18. PHASE I/II TRIAL, INTRACAVITARY LAK/IL-2 IN BRAIN TUMORS
    Maxim Koslow; Fiscal Year: 1991
    ..activated LAK cells with IL- 2 on the first day of treatment, via an Ommaya reservoir implanted at the time of reoperation. Additional IL-2 alone will be given for a total of 3x weekly for 2 weeks to complete a single cycle...
  19. IMPROVED ALLOGRAFT HEART VALVE PRESERVATION
    Kelvin Brockbank; Fiscal Year: 2003
    ..It is anticipated that modification or reduction of ice formation in cryopreserved valves should decrease the need for reoperation due to structural deterioration and calcification in allograft recipients.
  20. CW HOLMIUM LASER VENTRICULAR FENESTRATION
    Kathleen McMillan; Fiscal Year: 1993
    ..At present, shunt revision is by far the most common neurosurgical reoperation being performe Radiation from a 2...
  21. RADIOTHERAPY--PREVENT FIBROSIS AFTER LUMBAR LAMINECTOMY
    Peter Gerszten; Fiscal Year: 2001
    ..Fibrosis may be the underlying cause in as many as a quarter of all failed back surgery syndrome cases. Reoperation with the intention of excising this fibrous tissue often produces a poor surgical result and further scarring...
  22. Biocompatiibility of Rapidly Exchangeable Heart Valve
    Todd Campbell; Fiscal Year: 2003
    ..We have addressed the durability problems of bioprosthetic valves, and the associated risk of reoperation, by developing a rapidly exchangeable bioprosthetic valve that can be replaced without conventional open-heart ..
  23. BIOELASTIC MATERIALS FOR STRABISMUS AND RETINAL SURGERY
    Channe Gowda; Fiscal Year: 1993
    ..Such a material should have significant clinical application, particularly in reoperation procedures for strabismus and retinal detachment surgery involving the extraocular muscles...
  24. Rapid Exchangeable Bioprosthetic Heart Valve
    Todd Campbell; Fiscal Year: 2003
    ..approach to dealing with the durability problems of bioprosthetic valves, and the associated risk of reoperation. The VALVEXCHANGE procedure enables tissue-based heart valves to be replaced without conventional open-heart ..
  25. GASTRIC BAND SYSTEM FOR TREATMENT OF OBESITY
    DELORES GRAHAM; Fiscal Year: 1992
    ..injection port that can be accessed percutaneously, permitting stoma size adjustment postoperatively, without reoperation. Early data are promising, with perioperative complication rate of 3...
  26. Complications of Surgery for Spinal Stenosis: A Clinical Prediction Rule
    Richard A Deyo; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: A new method for estimating surgical risk will improve patient safety and assist in surgical decision-making, informed consent, monitoring surgical products, &improving quality assessment. ..
  27. Cardiac care in specialty and general hospitals
    Peter M Cram; Fiscal Year: 2010
    ..Together these analyses will provide much needed information on the relative quality of care provided by specialty cardiac hospitals to policy makers, payors, providers and patients. ..
  28. Biomarkers of COX-2 inhibitors in intraductal papillary mucinous neoplasm (IPMN)
    Christian Schmidt; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  29. Neoadjuvant Cytokine Immunotherapy by PLA Microspheres
    Michael Sabel; Fiscal Year: 2007
    ..I will pursue this area of investigation as a full-time faculty member, with full commitment from the Department of General Surgery and the Division of Surgical Oncology at the University of Michigan Medical Center. ..
  30. Osteolysis and Implant Wear: Biological, Biomedical Engineering, and Surgical Pri
    Stuart Goodman; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  31. ADIPOSE DERIVED STEM CELLS FOR TREATMENT OF INCONTINENCE
    LARISSA RODRIGUEZ; Fiscal Year: 2008
    ..Lastly, we will use an animal model of incontinence and decreased urethral resistance to test the hypothesis that these cells can be used to reconstruct a functional urethra as a treatment of stress incontinence. ..
  32. Use of Quantitative RT-PCR for Staging Esophageal Cancer
    James Luketich; Fiscal Year: 2009
    ..In addition, we believe that this research will answer some very interesting questions about tumor biology and metastasis in esophageal cancer. ..
  33. Measuring the Efficacy of Endovascular Treatment of AAA
    Peter Faries; Fiscal Year: 2007
    ..abstract_text> ..
  34. Improving Treatment of Newly Diagnosed Osteoporosis
    Peter Cram; Fiscal Year: 2009
    ..Finally, this work will serve as a model for examining the barriers to and improving treatment of other chronic diseases identified through screening. ..
  35. Beaumont Interstitial Cystitis Clinical Research Network
    Kenneth Peters; Fiscal Year: 2007
    ..Adverse events and complications will be monitored. Ancillary studies as agreed upon by the ICCRN will be carried out in conjunction with the clinical trial. ..
  36. Racial Disparities in Inflammatory Bowel Disease
    GEOFFREY NGUYEN; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  37. MODEL FOR PELVIC FLOOR DISORDERS
    Amanda Clark; Fiscal Year: 2004
    ..abstract_text> ..
  38. Genetic Mutations in Gliomatosis Cerebri
    Marcus Ware; Fiscal Year: 2004
    ..We shall use this data to determine if there are specific patterns of chromosome aberrations that are characteristic of GC. Our final goal is to compare copy-number aberrations seen in GC to those seen in other non-GC astrocytic tumors. ..
  39. Ischemia-Reperfusion Injury in Cardiac Surgery
    William Holman; Fiscal Year: 2004
    ....
  40. RCT of Arthroscopic Partial Meniscectomy in OA
    Jeffrey Katz; Fiscal Year: 2004
    ..If funded, these planning activities would enable us initiate the full trial with minimal delay. ..
  41. ACTIVE IMMUNOTHERAPY FOR GLIOBLASTOMA
    John Yu; Fiscal Year: 2004
    ..A phase II trial will be initiated in year 3 of the training grant based on the phase I studies. ..
  42. SACRAL CREST CELLS AND ENTERIC NEURODEVELOPMENT
    Raj Kapur; Fiscal Year: 2005
    ..The results of this study will further our understanding of normal enteric neurodevelopment and congenital disorders of intestinal motility. ..
  43. Bridge to neonatal Fontan repair of single ventricle
    Mark Rodefeld; Fiscal Year: 2006
    ..abstract_text> ..
  44. Enhanced Drug Delivery to Metastatic Brain Tumors
    Keith Black; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  45. Infusion of Particles at Implant interfeces
    Stuart Goodman; Fiscal Year: 2006
    ..abstract_text> ..
  46. Human Bone Marrow Derived Neural Stem Cell Therapy
    John Yu; Fiscal Year: 2006
    ..3) Human BM-NSC is safe and effective in an experimental rodent glioma model. ..
  47. BIOCHEMICAL CONTROL OF BBB IN ABNORMAL BRAIN CAPILLARIES
    Keith Black; Fiscal Year: 2006
    ..The results of the proposed work have implications in enhanced and potentially targeted drug delivery to the brain. ..
  48. Hydrocephalus, Intracranial Pressure and Neurocognition
    David Frim; Fiscal Year: 2006
    ..At the study conclusion, derived data should also practically affect the surgical choice of shunting products. ..
  49. EFFECT OF COMP MUTATION ON MUSCULOSKELETAL DEVELOPMENT
    Paul Di Cesare; Fiscal Year: 2002
    ..Identifying the functions, synthesis, interactions, tissue distribution and expression of COMP is critical to understanding its influence on growth during endochondral ossification and articular cartilage structure and function. ..
  50. EARLY DETECTION OF GLAUCOMA DAMAGE
    Henry Jampel; Fiscal Year: 2004
    ..This assessment of the RTA and NFA will help to establish their utility as outcome measures for clinical management of glaucoma, epidemiological research, and clinical trials. ..
  51. Identification and characterization of the DFNB17 gene
    John Greinwald; Fiscal Year: 2006
    ....
  52. JCV Virus Expression in Oropharynx and HIV
    Joseph Berger; Fiscal Year: 2004
    ..This line of investigation would add credence to an oropharyngeal mechanism of JCV transmission and may ultimately lead to the clinical identification of an acute illness attributable to this pathogen. ..
  53. Clinical Approaches to Ileal Pouch Dysfunction
    Bo Shen; Fiscal Year: 2005
    ..The AIMS of study are to 1) investigate visceral hypersensitivity using barostat examination of the pouch; 2) conduct a randomized, placebo-controlled clinical trial evaluating the use of amitriptyline in IPS. ..
  54. Effect of AADC gene transfer on L-dopa induced dyskinesia in MPTP monkeys
    Robert Richardson; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  55. Glucose Regulation of Pancreatic Islet Gene Experession
    RODERICK PAUL ROBERTSON; Fiscal Year: 2010
    ..We will study whether increasing antioxidant protection protects these cells and prevents deterioration of glucose control in diabetes. ..
  56. MENTORING & ADVANCED RESEARCH TRAINING FOR WRHR SCHOLARS
    Jonathan Berek; Fiscal Year: 2008
    ..This cadre of Scholars will be among future leaders in women's reproductive health research in the United States. [unreadable] [unreadable] [unreadable]..
  57. Basic Science of Tendon To Bone Healing
    Asheesh Bedi; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  58. REAL-TIME FLUORESCENCE-ACTIVATED RENAL MONITOR
    CARLOS RABITO; Fiscal Year: 2002
    ..proposed commercial application: not available ..
  59. MECHANISMS OF IMPLANT PARTICLE-INDUCED OSTEOCLASTOGENESI
    John Clohisy; Fiscal Year: 2002
    ..Our aims are: 1) to determine the mechanism(s) by which PMMA particles induce NF-kB activation in osteoclast precursor cells and 2) to determine the effect of blocking NF-kB activation on PMMA-induced osteoclastogenesis in vitro. ..