tissue expansion

Summary

Summary: Process whereby tissue adjacent to a soft tissue defect is expanded by means of a subcutaneously implanted reservoir. The procedure is used in reconstructive surgery for injuries caused by trauma, burns, or ablative surgery.

Top Publications

  1. ncbi Reconstruction of major forehead soft tissue defects with adjacent tissue and minimal scar formation
    Esmail Hassanpour
    Department of Plastic Surgery, 15 Khordad Hospital, Tehran, Iran
    J Craniofac Surg 16:1126-30. 2005
  2. ncbi Scalp reconstruction
    Babak J Mehrara
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Surg Oncol 94:504-8. 2006
  3. ncbi Bone marrow-derived mesenchymal stem cells transplantation accelerates tissue expansion by promoting skin regeneration during expansion
    Mei Yang
    Department of Plastic and Reconstructive Surgery, Shanghai Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Ann Surg 253:202-9. 2011
  4. ncbi Adipose tissue-derived stem cells (ADSCs) transplantation promotes regeneration of expanded skin using a tissue expansion model
    Lingling Sheng
    Department of Plastic and Reconstructive Surgery, Shanghai Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Wound Repair Regen 21:746-54. 2013
  5. ncbi The use of acellular dermal matrix in immediate two-stage tissue expander breast reconstruction
    Katie E Weichman
    New York University Langone Medical Center, Institute of Reconstructive Plastic Surgery, New York, NY, USA
    Plast Reconstr Surg 129:1049-58. 2012
  6. ncbi Comparison of implant-based immediate breast reconstruction with and without acellular dermal matrix
    Andrew J Vardanian
    Division of Plastic and Reconstructive Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    Plast Reconstr Surg 128:403e-410e. 2011
  7. ncbi Combined tissue expansion and prelamination of forearm flap in major ear reconstruction
    Yuan Cheng Chiang
    Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University, Chia Yi, Taiwan
    Plast Reconstr Surg 117:1292-5. 2006
  8. ncbi Combining scalp tissue expansion with porous polyethylene total ear reconstruction in burned patients
    Daniel N Driscoll
    Division of Plastic Surgery, Shriners Hospital for Children, Boston, MA, USA
    Ann Plast Surg 64:183-6. 2010
  9. ncbi Transplantation of stromal vascular fraction as an alternative for accelerating tissue expansion
    Lingling Sheng
    Department of Plastic and Reconstructive Surgery, Shanghai Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China
    J Plast Reconstr Aesthet Surg 66:551-7. 2013
  10. ncbi Healing time of radial forearm free flap donor sites after preoperative tissue expansion: randomized controlled trial
    James P Bonaparte
    Department of Otolaryngology Head and Neck Surgery, The University of Ottawa, Ottawa, ON
    J Otolaryngol Head Neck Surg 40:S20-7. 2011

Detail Information

Publications229 found, 100 shown here

  1. ncbi Reconstruction of major forehead soft tissue defects with adjacent tissue and minimal scar formation
    Esmail Hassanpour
    Department of Plastic Surgery, 15 Khordad Hospital, Tehran, Iran
    J Craniofac Surg 16:1126-30. 2005
    ..There were no serious complications such as hematoma, bleeding, infection, or flap necrosis. We recommend this technique for reconstruction of extensive forehead soft tissue defects...
  2. ncbi Scalp reconstruction
    Babak J Mehrara
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Surg Oncol 94:504-8. 2006
    ..Current techniques used for scalp reconstruction after surgical ablation are the subject of this review...
  3. ncbi Bone marrow-derived mesenchymal stem cells transplantation accelerates tissue expansion by promoting skin regeneration during expansion
    Mei Yang
    Department of Plastic and Reconstructive Surgery, Shanghai Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Ann Surg 253:202-9. 2011
    To evaluate the effect of bone marrow-derived mesenchymal stem cells (BM-MSCs) transplantation on tissue expansion.
  4. ncbi Adipose tissue-derived stem cells (ADSCs) transplantation promotes regeneration of expanded skin using a tissue expansion model
    Lingling Sheng
    Department of Plastic and Reconstructive Surgery, Shanghai Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China
    Wound Repair Regen 21:746-54. 2013
    ..To clarify the roles, a tissue expansion model was used in this study...
  5. ncbi The use of acellular dermal matrix in immediate two-stage tissue expander breast reconstruction
    Katie E Weichman
    New York University Langone Medical Center, Institute of Reconstructive Plastic Surgery, New York, NY, USA
    Plast Reconstr Surg 129:1049-58. 2012
    Acellular dermal matrix is commonly used in implant-based breast reconstruction to allow for quicker tissue expansion with better coverage and definition of the lower pole of the breast...
  6. ncbi Comparison of implant-based immediate breast reconstruction with and without acellular dermal matrix
    Andrew J Vardanian
    Division of Plastic and Reconstructive Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90024, USA
    Plast Reconstr Surg 128:403e-410e. 2011
    ..Its performance profile remains equivocal. The authors studied whether adding it in implant-based immediate breast reconstruction improved outcomes when compared with non-acellular dermal matrix reconstruction...
  7. ncbi Combined tissue expansion and prelamination of forearm flap in major ear reconstruction
    Yuan Cheng Chiang
    Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University, Chia Yi, Taiwan
    Plast Reconstr Surg 117:1292-5. 2006
  8. ncbi Combining scalp tissue expansion with porous polyethylene total ear reconstruction in burned patients
    Daniel N Driscoll
    Division of Plastic Surgery, Shriners Hospital for Children, Boston, MA, USA
    Ann Plast Surg 64:183-6. 2010
    ..A total loss of the pinna from burns is rare and often associated with significant alopecia. Tissue expansion is an excellent means of reconstructing burned scalp alopecia...
  9. ncbi Transplantation of stromal vascular fraction as an alternative for accelerating tissue expansion
    Lingling Sheng
    Department of Plastic and Reconstructive Surgery, Shanghai Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai 200011, PR China
    J Plast Reconstr Aesthet Surg 66:551-7. 2013
    b>Tissue expansion has been a good option for repair and reconstruction of large soft-tissue defects. However, the long expansion process, as well as accompanied complications, still remains the major problem of this technique...
  10. ncbi Healing time of radial forearm free flap donor sites after preoperative tissue expansion: randomized controlled trial
    James P Bonaparte
    Department of Otolaryngology Head and Neck Surgery, The University of Ottawa, Ottawa, ON
    J Otolaryngol Head Neck Surg 40:S20-7. 2011
    The objective of this study is to test the hypothesis that using a simple and inexpensive preoperative tissue expansion device for radial forearm free flap donor sites will result in a significant reduction in healing time and reduced ..
  11. ncbi Cost-effectiveness of a topically applied pre-operative tissue expansion device for radial forearm free flaps: a cohort study
    J P Bonaparte
    Department of Otolaryngology Head and Neck Surgery, The University of Ottawa, Ottawa, ON, Canada
    Clin Otolaryngol 36:345-51. 2011
    The objective of this study is to test the hypothesis that using a non-invasive and inexpensive pre-operative tissue expansion device (DynaClose) for radial forearm free-flap donor sites will result in a significant reduction in the cost ..
  12. ncbi Assessment of facial tissue expansion with three-dimensional digitizer scanning
    Ying Ji
    Division of Plastic Surgery, University of Mississippi Medical Center, Jackson, Mississippi, USA
    J Craniofac Surg 13:687-92. 2002
    ..article reports a three-dimensional (3D) digital color scanning system used in the measurement of facial soft tissue expansion. This system consists of digital scanning equipment, software for stereolithographical (STL) forms and ..
  13. ncbi Staged scalp soft tissue expansion before delayed allograft cranioplasty: a technical report
    Ekkehard M Kasper
    Department of Surgery, Division of Neurological Surgery, Beth Israel Deaconess Medical Center, Boston, Massachusetts 02215, USA
    Neurosurgery 71:15-20; discussion 21. 2012
    ..Hemicraniectomy is an established neurosurgical procedure. However, before cranial vault reconstruction, it is imperative that sufficient scalp soft tissue is available for coverage of the reconstructed skull...
  14. pmc Growing skin: tissue expansion in pediatric forehead reconstruction
    Alexander M Zöllner
    Department of Mechanical Engineering, Stanford University, Stanford, CA 94305, USA
    Biomech Model Mechanobiol 11:855-67. 2012
    b>Tissue expansion is a common surgical procedure to grow extra skin through controlled mechanical over-stretch...
  15. ncbi A systematic review and meta-analysis of complications associated with acellular dermal matrix-assisted breast reconstruction
    Goretti Ho
    Division of Plastic and Reconstructive Surgery, Keck School of Medicine of University of Southern California, Los Angeles, CA 90033, USA
    Ann Plast Surg 68:346-56. 2012
    ..The purpose of this study was to conduct a systematic review and meta-analysis to determine an aggregate estimate of risks associated with ADM-assisted breast reconstruction...
  16. ncbi Complications in tissue expander breast reconstruction: a comparison of AlloDerm, DermaMatrix, and FlexHD acellular inferior pole dermal slings
    Sebastian Brooke
    Division of Plastic Surgery, The Pennsylvania State University, College of Medicine, Penn State Milton S Hershey Medicine Center, Hershey, PA 17033 0850, USA
    Ann Plast Surg 69:347-9. 2012
    ..Isolating infectious complications, there is a trend toward increased incidence with ADM compared to reconstructions without...
  17. ncbi Human acellular dermis versus no acellular dermis in tissue expansion breast reconstruction
    Joseph W Parks
    Plastic Surgery Group of Memphis, Tenn, USA
    Plast Reconstr Surg 130:739-46. 2012
    ..Recently, concerns have arisen about an increase in postoperative complications with its use...
  18. ncbi Medium-term cost analysis of breast reconstructions in a single Dutch centre: a comparison of implants, implants preceded by tissue expansion, LD transpositions and DIEP flaps
    T H C Damen
    Department of Plastic and Reconstructive Surgery, Erasmus Medical Centre, P O Box 2040, NL 3000 CA Rotterdam, The Netherlands
    J Plast Reconstr Aesthet Surg 64:1043-53. 2011
    ..was to assess the economic implications of four BR techniques: silicone prosthesis (SP), implant preceded by tissue expansion (TE/SP), latissimus dorsi transposition with or without implant (LD ± SP) and deep inferior epigastric ..
  19. ncbi Acellular dermis-assisted breast reconstruction with the use of crescentric tissue expansion: a functional cosmetic analysis of 40 consecutive patients
    Donald W Buck
    Division of Plastic and Reconstructive Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
    Aesthet Surg J 30:194-200. 2010
    ..Crescentric tissue expanders have the potential to improve postoperative aesthetic results via selective lower pole expansion; however, limited data are available on their efficacy...
  20. ncbi Expander/implant reconstruction with AlloDerm: recent experience
    James D Namnoum
    Atlanta Plastic Surgery, Atlanta, GA 30342, USA
    Plast Reconstr Surg 124:387-94. 2009
    ....
  21. ncbi Incisional hernia repair: abdominoplasty, tissue expansion, and methods of augmentation
    Hendrikus J A A Van Geffen
    Department of Surgery, Jeroen Bosch Hospital GZG, P O Box 90153, 5200 ME s Hertogenbosch, The Netherlands
    World J Surg 29:1080-5. 2005
    ..Treatment of this condition by the above-mentioned means should therefore be proposed on an individual basis utilizing one or more of the many possible techniques described...
  22. ncbi Implant reconstruction in breast cancer patients treated with radiation therapy
    Jeffrey A Ascherman
    Division of Plastic Surgery, Department of Surgery, Columbia University Medical Center, New York, NY 10032 3784, USA
    Plast Reconstr Surg 117:359-65. 2006
    ..Implant reconstruction in breast cancer patients treated with radiation therapy is controversial. Prior studies are limited by older prosthetic devices, reconstructive techniques, and radiation therapy protocols...
  23. ncbi Tissue expansion for the delayed closure of large myelomeningoceles
    David J Mowatt
    Department of Craniofacial and Plastic Surgery, Great Ormond Street Hospital for Children, London, United Kingdom
    J Neurosurg 103:544-8. 2005
    ..Numerous techniques for the soft-tissue closure of large myelomeningoceles have been described. When patients present for delayed repair beyond the neonatal period, the indications for surgery are both different and less immediate...
  24. ncbi Latissimus dorsi breast reconstruction utilizing functional muscle transfer and tissue expansion
    Bruce A Mast
    aCCent Plastic and Cosmetic Surgery, Gainesville, FL 32653, USA
    Ann Plast Surg 56:36-9. 2006
    ..of the classic latissimus reconstruction: muscle transferred as an innervated functional unit and tissue expansion posterior to the latissimus but anterior to the pectoralis muscle...
  25. ncbi Tissue expansion-assisted closure of massive ventral hernias
    Nho V Tran
    Division of Plastic Surgery, Mayo Clinic, Rochester, MN 55905, USA
    J Am Coll Surg 196:484-8. 2003
  26. ncbi Use of self-expanding, hydrophilic osmotic expanders (hydrogel) in the reconstruction of congenital clinical anophthalmos
    Robert A Mazzoli
    Department of Ophthalmology, Madigan Army Medical Center, Tacoma, WA 98431, USA
    Curr Opin Ophthalmol 15:426-31. 2004
    ..Recent advances in tissue expansion technology may offer additional, novel alternatives to conventional therapies.
  27. ncbi Scrotal reconstruction using rapid intraoperative tissue expansion: a preliminary report
    Eric O Kwon
    Division of Urology, Lenox Hill Hospital, New York, New York, USA
    J Urol 179:207-9. 2008
    ..However, large defects usually require reconstruction using flaps or grafts. We present a novel technique of scrotal closure using rapid intraoperative tissue expansion to manage select extensive partial scrotal defects.
  28. ncbi Retrospective analysis of tissue expansion in reconstructive burn surgery: evaluation of complication rates
    A Bozkurt
    Department of Plastic, Reconstructive, and Hand Surgery, Burn Center, University Hospital RWTH Aachen, Germany
    Burns 34:1113-8. 2008
    b>Tissue expansion is a widespread and accepted concept in reconstructive surgery, but is also afflicted with a variety of complications...
  29. ncbi External filling ports in tissue expansion: confirming their safety and convenience
    Mustafa Keskin
    Institute for Craniofacial and Reconstructive Surgery, Department of Plastic and Reconstructive Surgery, Providence Hospital, Southfield, Michigan, USA
    Plast Reconstr Surg 117:1543-51. 2006
  30. pmc Correlation of cutaneous tension distribution and tissue oxygenation with acute external tissue expansion
    C Marquardt
    Department of Surgery, Krankenhaus Ludwigsburg, Germany
    Eur J Med Res 14:480-6. 2009
    ..Taken together, we propose that even large defect wounds can be closed successfully using the mass displacement caused by expansion especially in areas where soft, voluminous tissue layers are present...
  31. ncbi The beginning of a new era in tissue expansion: self-filling osmotic tissue expander--four-year clinical experience
    Marc Alexander Ronert
    Department of Plastic Surgery, Kaiserswerther Diakonie, Florence Nightingale Hospital, Dusseldorf, Germany
    Plast Reconstr Surg 114:1025-31. 2004
    ..The expander is 10 percent of its final volume and only requires a short incision and a small pocket. An operation can easily be performed under local anesthesia, with minimal tissue mobilization in older children and compliant patients...
  32. ncbi Tissue expansion in the head and neck
    John F Hoffmann
    Spokane Center for Facial Plastic Surgery, 217 W Cataldo, Spokane, WA 99201, USA
    Facial Plast Surg Clin North Am 13:315-24, vii. 2005
    b>Tissue expansion can be a valuable adjunct in reconstruction of large defects of the head and neck and is particularly useful in the scalp and forehead region...
  33. ncbi Aesthetic reconstruction of large scalp defects by sequential tissue expansion without interval
    Ali Gurlek
    Department of Plastic and Reconstructive Surgery, Inonu University, Medical Faculty, Malatya, Turkey
    Aesthetic Plast Surg 28:245-50. 2004
    b>Tissue expansion is indicated in the reconstruction of various scalp defects when there is inadequate adjacent tissue to allow either primary closure of the defect or repair with a local flap...
  34. ncbi Tissue expansion using osmotically active hydrogel systems for direct closure of the donor defect of the radial forearm flap
    S J Berge
    Department of Oral and Maxillofacial Surgery, Friedrich Wilhelm University, Sigmund Freud Strasse 25, D 53105 Bonn, Germany
    Plast Reconstr Surg 108:1-5, discussion 6-7. 2001
    ..b>Tissue expansion appears to be a good alternative that allows the use of local tissues to ultimately improve the forearm donor-..
  35. ncbi Nasal reconstruction: experience using tissue expansion and forehead flap
    Ali A Kheradmand
    Department of Head and Neck Surgical Oncology and Reconstructive Surgery, The Cancer Institute, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
    J Oral Maxillofac Surg 69:1478-84. 2011
    ....
  36. ncbi Pediatric tissue expansion: our experience with 103 expanded flap reconstructive procedures in 41 children
    Livnat Dotan
    Department of Plastic and Reconstructive Surgery, Hadassah Medical Center and Hebrew University Hadassah Medical School, Jerusalem, Israel
    Isr Med Assoc J 11:474-9. 2009
    b>Tissue expansion is a well-recognized technique for reconstructing a wide variety of skin and soft tissue defects...
  37. ncbi A multidisciplinary protocol for planned skin-preserving delayed breast reconstruction for patients with locally advanced breast cancer requiring postmastectomy radiation therapy: 3-year follow-up
    Steven J Kronowitz
    Department of Plastic Surgery, University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Plast Reconstr Surg 127:2154-66. 2011
    ....
  38. ncbi Three-dimensional photogrammetry for surgical planning of tissue expansion in hemifacial microsomia
    Yasas S N Jayaratne
    Discipline of Oral and Maxillofacial Surgery, Faculty of Dentistry, The University of Hong Kong, Hong Kong
    Head Neck 32:1728-35. 2010
    ..We aim to illustrate the applications of 3-dimensional (3-D) photogrammetry for surgical planning and longitudinal assessment of the volumetric changes in hemifacial microsomia...
  39. ncbi Risk factors for complications of tissue expansion: a 20-year systematic review and meta-analysis
    Xiaolu Huang
    Department of Plastic and Reconstructive Surgery, Shanghai Ninth People s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People s Republic of China
    Plast Reconstr Surg 128:787-97. 2011
    b>Tissue expansion is a widespread and accepted concept in plastic and reconstructive surgery and burn treatment but is also associated with a variety of complications...
  40. ncbi Stretch and growth: the molecular and physiologic influences of tissue expansion
    Roger E De Filippo
    Laboratory for Tissue Engineering and Cellular Therapeutics, Children s Hospital and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA
    Plast Reconstr Surg 109:2450-62. 2002
  41. ncbi Radiotherapy: effects on expanded skin
    Cynthia M Goodman
    D ivision of Plastic Surgery, Baylor College of Medicine, Houston, TX, USA
    Plast Reconstr Surg 110:1080-3. 2002
    Although the combination of radiation and tissue expansion has been associated with a significant rate of complications, the specific pathophysiology has yet to be clearly elucidated...
  42. ncbi [Tissue expansion in surgical treatment of burn scars of the scalp]
    D Voulliaume
    Service des brûlés et de chirurgie réparatrice, centre hospitalier Saint Luc Saint Joseph, 20, Quai Claude Bernard, 69007 Lyon, France
    Ann Chir Plast Esthet 52:590-9. 2007
    Deep burns of the scalp responsible of alopecia, used to be a real surgical challenge until apparition of tissue expansion in the 1980's...
  43. ncbi The role of tissue expansion in the management of large congenital pigmented nevi of the forehead in the pediatric patient
    B S Bauer
    Division of Plastic Surgery, Children's Memorial Hospital, Northwestern University Medical School, Chicago, Illinois, USA
    Plast Reconstr Surg 107:668-75. 2001
    ..6) In general, one should always use the largest expander possible beneath the uninvolved forehead skin, occasionally even carrying the expander under the lesion. Expanders are often overexpanded...
  44. ncbi Immediate breast reconstruction in two stages using anatomical tissue expansion
    J R Castello
    Department of Plastic Surgery, Hospital Ramon y Cajal, Madrid, Spain
    Scand J Plast Reconstr Surg Hand Surg 34:167-71. 2000
    ..done for 56 patients with breast cancer followed by immediate reconstruction in two stages using anatomical tissue expansion. In 49 patients a permanent prosthesis was successfully implanted while three patients refused a further ..
  45. ncbi A new method: perforator-based tissue expansion for a preexpanded free cutaneous perforator flap
    Feng Chou Tsai
    Department of Plastic Surgery, Linkou Burn Center, Chang Gung Memorial Hospital, 5 Fu Hsin St, Kweishan, Taoyuan, Taiwan
    Burns 29:845-8. 2003
    ..Combination of preexpansion, perforator-based prefabrication of tissue expansion and a free anterolateral thigh flap is first introduced and developed to resurface the large territory of ..
  46. ncbi An accelerated approach to tissue expansion for breast reconstruction: experience with intraoperative and rapid postoperative expansion in 370 reconstructions
    Andrea L Pusic
    Department of Plastic and Reconstructive Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 111:1871-5. 2003
    Breast reconstruction with tissue expansion is a well-established technique that offers satisfactory aesthetic results with minimal patient morbidity...
  47. ncbi Chest wall deformity after tissue expansion
    Yakup Sariguney
    Department of Plastic, Reconstructive and Aesthetic Surgery, Gazi University, Faculty of Medicine, Ankara, Turkey
    Scand J Plast Reconstr Surg Hand Surg 42:108-9. 2008
    ..We present one, and surgeons should be cautious about the possibility of skeletal deformities in patients who are osteoporotic and postmenopausal who require prolonged tissue expansion.
  48. ncbi Pediatric tissue expansion: indications and complications
    John LoGiudice
    Department of Plastic Surgery, Medical College of Wisconsin, Milwaukee 53226, USA
    J Craniofac Surg 14:866-72. 2003
    b>Tissue expansion has become a major reconstructive modality in the past 30 years. Its application in the pediatric population has allowed the plastic surgeon to achieve functional and esthetic goals that were previously unobtainable...
  49. ncbi [A simple tissue expansion device for scalp defect]
    E Simon
    Service de chirurgie maxillofaciale et plastique, Hopital Central, 29, Avenue du Marechal de Lattre de Tassigny, CO no 60034, 54035 Nancy Cedex, France
    Rev Stomatol Chir Maxillofac 108:234-7. 2007
    ..The closure of scalp defects requires various procedures, but unfortunately with a high rate of sequels...
  50. doi Skin banking in autologous breast reconstruction
    Stephen J Kovach
    Plast Reconstr Surg 121:2177-8; author reply 2178. 2008
  51. ncbi Total face reconstruction using a pre-expanded, bilateral, extended, parascapular free flap
    Craig B Birgfeld
    Division of Plastic Surgery, The University of Pennsylvania, Philadelphia, PA, USA
    Ann Plast Surg 56:565-8. 2006
    ..This technique provided this patient with a large area of healthy skin and soft tissue that will ultimately provide this patient with an improved functional and esthetic result...
  52. ncbi Overexpansion technique in burn scar management
    Donatello Di Mascio
    Department of Surgery, Plastic Surgery and Burn Unit, Hospital Maggiore of Parma, University of Parma, Parma, Italy
    Burns 32:490-8. 2006
    ..Tissue overexpansion, if carefully planned and conducted, allows the completion of reconstruction in one-stage. Instead of serial expansions, it enhances patient compliance and reduces cost...
  53. ncbi [Tissue expansion for reconstruction of skin defects]
    Amin Kalaaji
    Plastikk og kjevekirurgisk avdeling Ullevål universitetssykehus 0407 Oslo
    Tidsskr Nor Laegeforen 128:1673-6. 2008
    Skin defects can reduce functions and can be aesthetically unpleasant. Tissue expansion for reconstruction of skin defects was introduced as a method in the plastic and maxillofacial surgery department, Ullevaal University Hospital, in ..
  54. ncbi Simultaneous reconstruction of breast and well-projected nipple after expansion of mammary skin
    Kotaro Yoshimura
    Department of Plastic Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    Scand J Plast Reconstr Surg Hand Surg 39:77-84. 2005
    ..Its disadvantages are the relatively weak blood supply of the flaps, and difficulty in calculating the position of the nipple. The procedure may be beneficial for selected cases...
  55. ncbi Total face reconstruction with one expanded free flap
    Hiroyuki Sakurai
    Department of Plastic and Reconstructive Surgery, Tokyo Women s Medical University, Tokyo, Japan
    Surg Technol Int 14:329-33. 2005
    ..This method did not require a separate tissue transfer for nasal reconstruction. To our knowledge, this is the first case of successful reconstruction with one flap for total face reconstruction that included the nose...
  56. ncbi Compression therapy after complex soft tissue trauma, and flap coverage: optimization of scar development, swelling, function, and aesthetic result
    C Can Cedidi
    Helios University Clinic, Clinic for Plastic and Hand Surgery, Aesthetic and Reconstructive Surgery, Heusnerstr 40, D 42283 Wuppertal, Germany
    Eur J Med Res 11:85-9. 2006
    ..The consequence is a significant step forward in the rehabilitation of these patients, and earlier social as well as professional reintegration...
  57. ncbi Reconstruction of acquired scalp defects: an algorithmic approach
    Jason E Leedy
    Department of Plastic Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75390 8820, USA
    Plast Reconstr Surg 116:54e-72e. 2005
    ..3. Understand the use of local tissue rearrangement for reconstruction of specific areas of the scalp. 4. Understand the use of tissue expansion and free tissue transfer for scalp reconstruction.
  58. ncbi Management of large melanocytic nevi in the extremities
    Julia Corcoran
    Children s Memorial Medical Center, Chicago, Illinois 60614, USA
    J Craniofac Surg 16:877-85. 2005
  59. ncbi Issues related to choice of breast reconstruction in early-stage breast cancer
    Kristina O'Shaughnessy
    Northwestern Plastic and Reconstructive Surgery, 675 North St Clair Street, 19th Floor, Chicago, IL 60611, USA
    Curr Treat Options Oncol 7:129-39. 2006
    ..This approach avoids radiation damage to tissue reconstruction flaps, saving them for use later if necessary. This approach, using a tissue expander as a first step, is growing in popularity...
  60. ncbi [Scalp surgery in children: principles and therapeutic aspects]
    A Picard
    Service de Chirurgie Maxillo faciale Pédiatrique, Hopital d Enfants Armand Trousseau, Assistance Publique des Hopitaux de Paris, UFR Saint Antoine, Universite Paris 6, 26, avenue du Dr Arnold Netter, 75571 Paris Cedex 12
    Rev Stomatol Chir Maxillofac 106:334-43. 2005
    ..Different surgical procedures are discussed: excision, tissue expansion, hair grafts...
  61. ncbi Combining multiple surgical techniques for maximum scar camouflage
    Steven Ross Mobley
    Division of Otolaryngology Head and Neck Surgery, University of Utah School of Medicine, Salt Lake City, USA
    Ear Nose Throat J 84:408-9. 2005
  62. ncbi Revisiting the reconstructive ladder
    Alexandra J Turner
    Plast Reconstr Surg 118:267-8. 2006
  63. ncbi Reconstruction of the face and neck scar contractures using staged transfer of expanded "Super-thin flaps"
    Jian hua Gao
    Department of Plastic and Reconstructive Surgery, Nanfang Medical University, Guangzhou, China
    Burns 33:760-3. 2007
    ..quot; In this report, we introduce expanded "Super-thin flaps" for reconstruction of the face and neck for the first time in a patient...
  64. ncbi Mastectomy with immediate expander-implant reconstruction, adjuvant chemotherapy, and radiation for stage II-III breast cancer: treatment intervals and clinical outcomes
    Jean L Wright
    Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Int J Radiat Oncol Biol Phys 70:43-50. 2008
    ....
  65. ncbi [Skin expansion in cicatricial alopecia of the scalp: 18 cases]
    H Drissi Qeytoni
    Service de Chirurgie Plastique, chirurgie maxillofaciale et stomatologie, hôpital militaire d instruction Mohamed V, BP 10100, Rabat, Maroc
    Rev Stomatol Chir Maxillofac 108:411-8. 2007
    ..This article had for aim to define the importance and limits of this technique in the treatment of alopecia and to highlight its relevance compared to other methods...
  66. ncbi Surgical management of large and giant congenital pigmented nevi of the lower extremity
    Zol B Kryger
    Division of Plastic Surgery, Children s Memorial Hospital, Chicago, Ill 60614, USA
    Plast Reconstr Surg 121:1674-84. 2008
    ..The surgical treatment of large and giant congenital pigmented nevi of the lower extremity is a challenging endeavor with limited reconstructive options...
  67. ncbi Esthetic outcomes of genitoplasty in males born with bladder exstrophy and epispadias
    Brian A VanderBrink
    Department of Pediatric Urology, Schneider s Children Hospital, New Hyde Park, New York, New York, USA
    J Urol 178:1606-10; discussion 1610. 2007
    ..We reviewed our long-term outcomes of genitoplasty in males born with exstrophy-epispadias complex with emphasis on the esthetic results...
  68. ncbi Super-thin abdominal skin pedicle flap for the reconstruction of hypertrophic and contracted dorsal hand burn scars
    J Gousheh
    Department of Plastic and Reconstructive Surgery, Shahid Beheshti University of Medical Sciences, 15 Khordad Hospital, Tehran, Iran
    Burns 34:400-5. 2008
    ..Therefore, this procedure can be considered a reliable and technically simple modality in the treatment of dorsal hand burn contractures...
  69. ncbi Reconstruction of perioral burn deformities in male patients by using the expanded frontal scalp
    Hiroyuki Sakurai
    Department of Plastic and Reconstructive Surgery, Tokyo Women s Medical University, 8 1 Kawada cho Shinjuku ku, Tokyo 162 8666, Japan
    Burns 33:1059-64. 2007
  70. ncbi Gains from the separation of two cases of conjoined twins
    Jiaming Sun
    Plastic Surgery Department, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, China
    J Plast Reconstr Aesthet Surg 61:552-6. 2008
    ..Conjoined twins are rare congenital malformations. Those who were successfully separated with both twins surviving are even more rare...
  71. ncbi Aesthetic management of external skin paddles following microvascular reconstruction of the head and neck
    Grigoriy Mashkevich
    Department of Otolaryngology, Head and Neck Surgery, New York Eye and Ear Infirmary, New York, New York 10003, USA
    Facial Plast Surg 24:65-8. 2008
    ..This article describes several options available in the postoperative setting to improve the appearance of transferred skin paddles. Regional tissue rearrangement with the submental and posterior scalping flaps is discussed in detail...
  72. ncbi Use of an expanded temporoparietal fascial flap technique for total auricular reconstruction
    Metin Kerem
    Plast Reconstr Surg 119:2320-1; author reply 2321. 2007
  73. ncbi The expanded supraclavicular flap, prefabricated with thoracoacromial vessels, for reconstruction of postburn anterior cervical contractures
    Alexander Margulis
    Department of Plastic Surgery, Hadassah Medical Center of Hebrew University, Jerusalem, Israel
    Plast Reconstr Surg 119:2072-7; discussion 2078-9. 2007
    ....
  74. ncbi Advances in scalp reconstruction
    Samson Lee
    Department of Otolaryngology, University of California at Davis, Sacramento, 95817, USA
    Curr Opin Otolaryngol Head Neck Surg 14:249-53. 2006
    ..The present review summarizes traditional and advanced techniques used to reconstruct defects of the scalp. These deformities range from small defects that can be closed primarily to significant defects, which require free tissue transfer...
  75. ncbi Aesthetic aspects of bladder exstrophy: results of puboplasty
    Brian A VanderBrink
    Department of Pediatric Urology, Schneider s Children Hospital, New Hyde Park, NY, USA
    J Urol 176:1810-5. 2006
    ..We present our retrospective case series of the experience of 1 surgeon during 27 years...
  76. ncbi [Port wine stains or capillary malformations: surgical treatment]
    C Berwald
    Service de chirurgie plastique reconstructrice et esthétique d adultes, Hopital de la Conception, 147, boulevard Baille, 13005 Marseille, France
    Ann Chir Plast Esthet 51:369-72. 2006
    ....
  77. ncbi Preexpanded distant "super-thin" intercostal perforator flaps for facial reconstruction without the need for microsurgery
    F Lu
    Department of Plastic and Reconstructive Surgery, Southern Medical University, Guangzhou, China
    J Plast Reconstr Aesthet Surg 59:1203-8. 2006
    ..Concept of the 'super-thin perforator flap' was introduced in 1994 by authors. Since then, various types of 'super-thin perforator flaps' were applied successfully especially for contour sensitive reconstruction such as face and neck...
  78. ncbi Breast reconstruction with alloplastic implants
    Siamak Agha-Mohammadi
    University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    J Surg Oncol 94:471-8. 2006
    ..With recent studies suggesting survival advantage of post-mastectomy irradiation, many candidates for breast reconstruction are receiving radiotherapy, which complicates healing after breast reconstruction...
  79. ncbi Tissue expansion in burn sequelae repair
    João Medeiros Tavares Filho
    Clementino Fraga Filho University Hospital of Rio de Janeiro, Hospital Santa Teresa and Beneficência Portuguesa of Petrópolis, Brazil
    Burns 33:246-51. 2007
    ..The rate of complications was 24.07%, of which 30.8% were considered to be absolute and 69.2% relative. Tissue expansion is an excellent option for burn sequelae treatment because it provides skin of similar local characteristics ..
  80. ncbi [Oncoplastic surgery in breast cancer: indications and results]
    Pierre Azuar
    Service de Chirurgie Gynécologique et Sénologique, Centre Hospitalier, 06335 Grasse, USA
    Presse Med 36:341-56. 2007
    ..Reconstructive surgery of the breast is an integral part of breast cancer treatment. Multidisciplinary decision-making and honest information to patients are essential before any reconstructive surgery...
  81. ncbi A retrospective analysis of patient satisfaction with immediate postmastectomy breast reconstruction: comparison of three common procedures
    Alexandrina S Saulis
    Division of Plastic and Reconstructive Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA
    Plast Reconstr Surg 119:1669-76; discussion 1677-8. 2007
    ..The authors aimed to quantify overall patient satisfaction with three breast reconstruction techniques and identify factors that have influenced satisfaction...
  82. ncbi An algorithm for total and subtotal facial reconstruction using an expanded transposition flap: a 20-year experience
    Robert J Spence
    Johns Hopkins School of Medicine, Baltimore, MD, USA
    Plast Reconstr Surg 121:795-805. 2008
    ..The author presents an algorithm developed for total and subtotal reconstruction of the face using an expanded shoulder transposition flap as a key element...
  83. ncbi Reconstructive surgeries after extensive burns in children
    I Suchanek
    Department of Burn and Reconstructive Surgery, University Hospital, Brno, Czech Republic
    Acta Chir Plast 45:139-43. 2003
    ....
  84. ncbi The 'RITE' use of the Fricke flap in periorbital reconstruction
    G Wilcsek
    Manchester Royal Eye Hospital, Manchester, UK
    Eye (Lond) 19:854-60. 2005
    ..present cases to illustrate the usefulness of the Fricke flap and describe a method of rapid intraoperative tissue expansion (RITE), which can enhance the applicability and effectiveness of the Fricke flap...
  85. ncbi Alopecia treatment with scalp expansion: some surgical fine points and a simple modification to improve the results
    Ufuk Bilkay
    Department of Plastic and Reconstructive Surgery, Ege University, Izmir, Turkey
    J Craniofac Surg 15:758-65. 2004
    ..study, authors present their clinical experience with the esthetic reconstruction of alopecia by means of a tissue expansion technique in 74 consecutive patients who were treated between May 1986 and June 2002 in the Department of ..
  86. ncbi Mammareconstruction with skin-expander and silicone prostheses: 15 years' experience
    Giorgio Bronz
    Lugano, Switzerland
    Aesthetic Plast Surg 26:215-8. 2002
    ..In most cases reconstruction with Skin-Expander and silicone implants meets the patients' desires: low-risk operation, fewer additional scars, and similar and improved breasts on both sides...
  87. ncbi [The influence of expansion maintenance period upon in vivo skin tension and immediate stretch-back rate of the expanded skin]
    Xuejun Liu
    Department of Plastic Surgery, Shenzhen Central Hospital, Shenzhen 518036, China
    Zhonghua Zheng Xing Wai Ke Za Zhi 18:302-4. 2002
    ..The study was to investigate the influence of maintenance period of expansion upon skin tension and immediate stretch-back rate of the expanded skin...
  88. ncbi Cosmetic aspects of cranial reconstruction
    Kenneth Leong
    Division of Plastic and Reconstructive Surgery, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, TX 78229 3900, USA
    Neurosurg Clin N Am 13:491-503, vi. 2002
    ..Hair preservation/reconstruction and free flaps have markedly improved the soft tissue esthetic outcome. Restoration of bony contour has been facilitated by advanced craniofacial techniques and three-dimensional alloplast...
  89. ncbi Refinements of free tissue transfer for optimal outcome in lower extremity reconstruction
    Christopher A Marek
    Division of Plastic Surgery, University of Kentucky College of Medicine, Lexington, KY 40536, USA
    Ann Plast Surg 52:270-5; discussion 275. 2004
    ....
  90. ncbi Tissue expansion after inverted-T mammaplasty: can it be performed successfully?
    Matthew S Kilgo
    Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Ann Plast Surg 50:588-93. 2003
    ..reconstructive dilemma: Do mastectomy flaps that are traversed by surgical scars still allow for adequate tissue expansion and a good aesthetic result? The objective of this study was to evaluate the authors' experience with tissue ..
  91. ncbi Other ways to use tissue expanded flaps
    Donald A Hudson
    Department of Plastic and Reconstructive Surgery, University of Cape Town, Cape Town, South Africa
    Br J Plast Surg 57:336-41. 2004
    b>Tissue expansion can arguably be regarded as one of the revolutions in reconstructive plastic surgery. Another three applications (illustrated by three case reports) for tissue expansion are presented.
  92. ncbi Expanded occipito-cervico-pectoral flap for reconstruction of burned cervical contracture
    S Motamed
    Department of Plastic and Reconstructive Surgery, Shahid Beheshti University, Tehran, Iran
    Burns 29:842-4. 2003
    ..This is an alternative method of reconstruction burn scar of neck area...
  93. ncbi Areola-sparing mastectomy with immediate breast reconstruction
    Rache M Simmons
    Department of Surgery, New York Presbyterian Hospital, Weill Medical College of Cornell University, and Weill Cornell Breast Center, 425 East 61st Street, 8th Floor, New York, NY 10021, USA
    Ann Plast Surg 51:547-51. 2003
    ..There was 1 postoperative complication, which consisted of a localized wound infection. Overall the authors found that ASM with immediate reconstruction provides excellent aesthetic results with infrequent complications...
  94. ncbi Anterior neck reconstruction with pre-expanded free groin and scapular flaps
    Milomir Ninkovic
    Department of Plastic and Reconstructive Surgery, Ludwig Boltzmann Institute for Quality Control in Plastic and Reconstructive Surgery, Leopold Franzens University, Innsbruck, Austria
    Plast Reconstr Surg 113:61-8. 2004
    ..The advantages and drawbacks of using pre-expanded free flaps in the treatment of neck burn contractures are discussed...
  95. ncbi [Surgical depilation in low hairline aurical reconstruction]
    Yong Tang
    Plastic Surgery Hospital Chenese Academy of Medical Sciences, Peking Union Medical College, Beijing 10041, China
    Zhonghua Zheng Xing Wai Ke Za Zhi 18:297-8. 2002
    ..Low hairline is one of the most troublesome problem in auricle reconstruction. There was no satisfactory way to manage the problem. This article discuss surgical depilation to deal with this problem and reconstructed auricle...
  96. ncbi [The influence of over-expansion on the blood supply of an axial-pattern flap]
    Gang Lu
    Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Beijing 100041, China
    Zhonghua Zheng Xing Wai Ke Za Zhi 18:280-2. 2002
    ..To investigate the influence of over-expansion on the viability and vascularity of an axial-pattern flap...
  97. ncbi First experience of endoscopic implantation of tissue expanders in plastic and reconstructive surgery
    V I Sharobaro
    Department of Reconstructive and Plastic Surgery, A V Vishnevsky Institute of Surgery, 27 B Serpukhovskaya Street, Moscow 113811, Russian Federation
    Surg Endosc 18:513-7. 2004
    Over the last 15 years, tissue expansion has been used in the treatment of 324 patients at the A. V. Vishnevsky Institute of Surgery...
  98. ncbi Pre-expanded ultra-thin supraclavicular flaps for (full-) face reconstruction with reduced donor-site morbidity and without the need for microsurgery
    Norbert Pallua
    Department of Plastic Surgery and Hand Surgery, Burn Center, University Hospital, Aachen University of Technology, Aachen, Germany
    Plast Reconstr Surg 115:1837-44; discussion 1845-7. 2005
    ..The authors report the use of this technique in 12 patients requiring large flaps who presented with extensive facial scarring that had been previously reconstructed using disfiguring, pigmented skin grafts...
  99. ncbi Expanded latissimus dorsi free flap for the treatment of extensive post-burn neck contracture
    Akihiko Takushima
    Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, University of Tokyo, Tokyo, Japan
    J Reconstr Microsurg 18:373-7. 2002
    ..It is suggested that tissue expansion prior to free flap transfer is useful for enlargement of the flap survival area and thinning of the flap.
  100. ncbi Breast reconstruction using tissue expanders and implants in Hodgkin's patients with prior mantle irradiation
    Norma Bacilious
    Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    Plast Reconstr Surg 109:102-7. 2002
    ..In this series, tissue expansion was reliable with low morbidity...
  101. ncbi [Breast burn sequelae. Classification and therapeutic indications]
    J P Comparin
    , , rue professeur Grignard, 69007 Lyon, France
    Ann Chir Plast Esthet 46:227-34. 2001
    ..The authors have spent part of their experience to treat acute case of thoracic burns, proposing classification of three types and specific treatment for each...

Research Grants28

  1. Keystone Symposia on Cellular and Molecular Basis of Metabolic Disorders Series
    JAMES WAVELL AIKEN; Fiscal Year: 2013
    ..The Adipose Tissue Biology meeting considers the role of angiogenesis in adipose tissue expansion;the white fat-brown fat debate;the contribution of the circadian clock to hormonal and neural signals ..
  2. The Function of Prohibitin / Annexin 2 Interaction in White Adipose Tissue
    Mikhail G Kolonin; Fiscal Year: 2013
    ..This will contribute to our understanding of the mechanisms governing WAT tissue expansion and provide valuable information on the biology of this protein complex potentially useful as a target of ..
  3. TYPE 2 DIABETES IN HISPANIC ADOLESCENTS
    MICHAEL ISAAC GORAN; Fiscal Year: 2013
    ..In Hypothesis 2, we propose that in extreme childhood obesity, there is a "saturation" of adipose tissue expansion during pubertal development, forcing deposition of fat into ectopic depots, which in turn adversely affects ..
  4. Fat Cell Size, Overfeeding &Ectopic Fat
    Eric Ravussin; Fiscal Year: 2011
    ..We hypothesize that individuals with both a poor potential for adipose tissue expansion and an impaired function of muscle mitochondria will have the most deterioration of insulin sensitivity after ..
  5. Epigenetic mechanisms and genes that regulate adipose tissue expansion
    Robert A Koza; Fiscal Year: 2013
    ..Understanding the mechanisms that regulate Mest and the catalytic function by which it controls fat mass expansion could identify novel therapeutic targets for the treatment of obesity. ..
  6. FUNCTIONAL DIVERSITY OF ORBITAL FIBROBLASTS
    Terry J Smith; Fiscal Year: 2011
    ..Central to TAO is anatomic-site selective inflammation and orbital tissue expansion caused by increased adipogenesis and accumulation of hyaluronan...
  7. Mechanisms of cell competition that regulate growth during development
    Laura A Johnston; Fiscal Year: 2013
    ..How cells communicate their growth status during tissue expansion, be it developmental or homeostatic, is largely unknown...
  8. Hippo signaling and the control of epidermal development and growth
    Fernando Camargo; Fiscal Year: 2013
    ..in the skin, the transcriptional effector of the Hippo pathway, YAP1, is essential for proper epidermal tissue expansion during development. Over-activation of YAP1 leads to progenitor expansion and tumor development...
  9. Delayed Hydrogel Tissue Expander
    Yourong Fu; Fiscal Year: 2010
    ..novel, delayed-swelling, hydrogel based, tissue expanders which do not suffer the drawbacks of current tissue expansion technologies...
  10. HGF Signaling in Adipose Tissue Growth and Metabolism
    Robert V Considine; Fiscal Year: 2010
    ..together, our published and novel preliminary observations suggest a central role for HGF to promote adipose tissue expansion via effects on both the vasculature and on preadipocytes...
  11. Delayed Hydrogel Tissue Expander
    Yourong Fu; Fiscal Year: 2007
    ..novel, delayed-swelling, hydrogel based, tissue expanders which do not suffer the drawbacks of current tissue expansion technologies...
  12. SCAR TISSUE INHIBITION AROUND SOFT TISSUE IMPLANTS
    Robert Whalen; Fiscal Year: 1990
    ..The textured surface also is to be evaluated for possible use on tissue expansion prostheses for reconstructive surgery...
  13. Developing Biomaterial Scaffolds That Delay Senescence in Mesenchymal Stem Cells
    Amanda Murphy; Fiscal Year: 2009
    ..but occur in low frequency in bone marrow, lack the ability to continuously divide under traditional ex vivo tissue expansion methods and eventually lose their differentiation potential...
  14. TRAINING PROGRAM IN DEVELOPMENTAL BIOLOGY
    Raymond Keller; Fiscal Year: 2003
    ..Support will be for the fist 3 years of graduate student or post- doctoral study, with the condition of good progress in training, or until individual awards are obtained. ..
  15. Akt-Regulated Gene Expression in Bladder Smooth Muscle
    Rosalyn Adam; Fiscal Year: 2005
    ..The information obtained from these studies will underpin and inform future studies that will be directed towards elucidation of the mechanism of action of Akt-regulated genes in bladder muscle. ..
  16. UCLA TRAINING PROGRAM IN NUTRITION AND OBESITY
    David Heber; Fiscal Year: 2007
    ..abstract_text> ..
  17. THE UCLA CLINICAL NUTRITION RESEARCH UNIT
    David Heber; Fiscal Year: 2006
    ..The UCLA CNRU is serving as a regional and national resource at the cutting edge of nutrition and cancer prevention research...
  18. Regional Lung Mechanics by 3D Image Registration
    Joseph M Reinhardt; Fiscal Year: 2010
    ..This information is now critical to the development and evaluation of new pulmonary disease therapies. ..
  19. LIPID METABOLISM IN FAT CELLS
    Wen Guo; Fiscal Year: 2010
    ..Together, these studies will provide new insights into the stress-induced regulation of lipogenesis in adipocytes, a potentially important avenue for modulating energy balance. ..
  20. Clinical Accommodation Measurement
    Adrian Glasser; Fiscal Year: 2010
    ....
  21. CELL MOTILITY AND CELL INTERACTIONS DURING NEURULATION
    Raymond Keller; Fiscal Year: 2001
    ..The combined approach of manipulating adhesion, recording cell motility with video-microscopy, and direct measurement of mechanical properties and forces promise to solve some long standing problems in neural development. ..
  22. FIBRILLIN AND EARLY XENOPUS PATTERNING
    Raymond Keller; Fiscal Year: 2002
    ..Dr. Keller will test specific hypotheses regarding the possible role of fibrillin in establishing the notochord/somite boundary, and in convergence and extension movements in Xenopus during gastrulation. ..
  23. Adrenal Cortical Cell Therapy
    James Dunn; Fiscal Year: 2008
    ..These studies will lead to a better understanding of the development of the adrenal cortex, as well as a new therapy that replaces the physiological function of the adrenal cortex. ..
  24. GENETICS OF DEVELOPMENTAL PLASTICITY IN THE ADIPOCYTE
    LESLIE KOZAK; Fiscal Year: 2004
    ..Finally (Aim 5), candidate cDNAs or genes will be tested by complementation in a cell culture system based on preadipocytes or BAC transgenesis using B6.A congenics. ..
  25. MOLECULAR GENETICS OF THERMOGENESIS
    LESLIE KOZAK; Fiscal Year: 2007
    ..Concurrent with gene identification, the experiments will provide phenotypic information on how these genes affect the development of excessive adiposity. ..
  26. Development of a Multi-phased Scaffold for Soft Tissue to Bone Integration
    Helen Lu; Fiscal Year: 2006
    ..abstract_text> ..
  27. Microarray Analysis of Wounds
    AMY COLWELL; Fiscal Year: 2004
    ..We hypothesize these genes can be used to modulate the biology of adult wound healing. This first step will form our basis for developing treatment to induce scarless healing. ..
  28. Accommodative changes in aging eyes
    Adrian Glasser; Fiscal Year: 2006
    ..This research will provide a foundation for studies directed at understanding if accommodation can be restored with artificial accommodative intraocular lenses. ..