cochlear implantation

Summary

Summary: Surgical insertion of an electronic hearing device (COCHLEAR IMPLANTS) with electrodes to the COCHLEAR NERVE in the inner ear to create sound sensation in patients with residual nerve fibers.

Top Publications

  1. pmc Neuroimaging with near-infrared spectroscopy demonstrates speech-evoked activity in the auditory cortex of deaf children following cochlear implantation
    Alexander B G Sevy
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA
    Hear Res 270:39-47. 2010
  2. pmc Systematic review of the literature on the clinical effectiveness of the cochlear implant procedure in paediatric patients
    F Forli
    Operative Unit of Otorhinolaryngology, Audiology and Phoniatrics, University of Pisa, Italy
    Acta Otorhinolaryngol Ital 31:281-98. 2011
  3. pmc Systematic review of the literature on the clinical effectiveness of the cochlear implant procedure in adult patients
    S Berrettini
    Operative Unit of Otorhinolaryngology, Audiology and Phoniatrics, University of Pisa, Italy
    Acta Otorhinolaryngol Ital 31:299-310. 2011
  4. ncbi Effects of round window dexamethasone on residual hearing in a Guinea pig model of cochlear implantation
    David P James
    Department of Otolaryngology, University of Melbourne, Parkville, Australia
    Audiol Neurootol 13:86-96. 2008
  5. ncbi Preservation of basal inner ear structures in cochlear implantation
    Oliver Adunka
    ENT Department, J W Goethe University, Frankfurt am Main, Germany
    ORL J Otorhinolaryngol Relat Spec 66:306-12. 2004
  6. ncbi Conservation of low-frequency hearing in cochlear implantation
    Jan Kiefer
    Clinic of Otorhinolaryngology, Head and Neck Surgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Otolaryngol 124:272-80. 2004
  7. ncbi Cochlear implantation via the round window membrane minimizes trauma to cochlear structures: a histologically controlled insertion study
    Oliver Adunka
    ENT Department, J W Goethe University, Frankfurt am Main, Germany
    Acta Otolaryngol 124:807-12. 2004
  8. ncbi Quantitative evaluation of new bone and fibrous tissue in the cochlea following cochlear implantation in the human
    Mehmet A Somdas
    Department of Otology and Laryngology, Harvard Medical School Massachusetts Eye and Ear Infirmary, Boston, Mass, USA
    Audiol Neurootol 12:277-84. 2007
  9. ncbi Preservation of low frequency hearing in partial deafness cochlear implantation (PDCI) using the round window surgical approach
    Henryk Skarzynski
    Institute of Physiology and Pathology of Hearing, Warsaw, Poland
    Acta Otolaryngol 127:41-8. 2007
  10. pmc Optical cochlear implants: evaluation of surgical approach and laser parameters in cats
    Suhrud M Rajguru
    Department of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 3008, USA
    Hear Res 269:102-11. 2010

Detail Information

Publications354 found, 100 shown here

  1. pmc Neuroimaging with near-infrared spectroscopy demonstrates speech-evoked activity in the auditory cortex of deaf children following cochlear implantation
    Alexander B G Sevy
    Bobby R Alford Department of Otolaryngology Head and Neck Surgery, Baylor College of Medicine, Houston, TX, USA
    Hear Res 270:39-47. 2010
    ..Therefore, NIRS can measure cortical responses in pediatric CI users, and has the potential to be a powerful adjunct to current CI assessment tools...
  2. pmc Systematic review of the literature on the clinical effectiveness of the cochlear implant procedure in paediatric patients
    F Forli
    Operative Unit of Otorhinolaryngology, Audiology and Phoniatrics, University of Pisa, Italy
    Acta Otorhinolaryngol Ital 31:281-98. 2011
    ..They considered as universally-accepted the usefulness/effectiveness of unilateral cochlear implantation in severely-profoundly deaf children...
  3. pmc Systematic review of the literature on the clinical effectiveness of the cochlear implant procedure in adult patients
    S Berrettini
    Operative Unit of Otorhinolaryngology, Audiology and Phoniatrics, University of Pisa, Italy
    Acta Otorhinolaryngol Ital 31:299-310. 2011
    ..They considered as universally accepted the usefulness/effectiveness of unilateral cochlear implantation in severely-profoundly adult patients...
  4. ncbi Effects of round window dexamethasone on residual hearing in a Guinea pig model of cochlear implantation
    David P James
    Department of Otolaryngology, University of Melbourne, Parkville, Australia
    Audiol Neurootol 13:86-96. 2008
    To study electric acoustic stimulation, we have developed a model of guinea pig cochlear implantation via a cochleostomy...
  5. ncbi Preservation of basal inner ear structures in cochlear implantation
    Oliver Adunka
    ENT Department, J W Goethe University, Frankfurt am Main, Germany
    ORL J Otorhinolaryngol Relat Spec 66:306-12. 2004
    ....
  6. ncbi Conservation of low-frequency hearing in cochlear implantation
    Jan Kiefer
    Clinic of Otorhinolaryngology, Head and Neck Surgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Otolaryngol 124:272-80. 2004
    ..have continued to improve, patients with some remaining cochlear function have become eligible for cochlear implantation. Thus, preservation of acoustic hearing after implantation has gained importance...
  7. ncbi Cochlear implantation via the round window membrane minimizes trauma to cochlear structures: a histologically controlled insertion study
    Oliver Adunka
    ENT Department, J W Goethe University, Frankfurt am Main, Germany
    Acta Otolaryngol 124:807-12. 2004
    ..To evaluate cochlear implant trauma to intracochlear structures when inserting the electrode via the round window membrane...
  8. ncbi Quantitative evaluation of new bone and fibrous tissue in the cochlea following cochlear implantation in the human
    Mehmet A Somdas
    Department of Otology and Laryngology, Harvard Medical School Massachusetts Eye and Ear Infirmary, Boston, Mass, USA
    Audiol Neurootol 12:277-84. 2007
    The formation of new bone and fibrous tissue in the human inner ear following cochlear implantation was evaluated by computer-assisted 3-D reconstruction...
  9. ncbi Preservation of low frequency hearing in partial deafness cochlear implantation (PDCI) using the round window surgical approach
    Henryk Skarzynski
    Institute of Physiology and Pathology of Hearing, Warsaw, Poland
    Acta Otolaryngol 127:41-8. 2007
    ..Successful hearing preservation is possible in individuals with excellent low frequency hearing. This is possible due to the partial insertion of an atraumatic electrode using an atraumatic round window surgical technique...
  10. pmc Optical cochlear implants: evaluation of surgical approach and laser parameters in cats
    Suhrud M Rajguru
    Department of Otolaryngology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611 3008, USA
    Hear Res 269:102-11. 2010
    ..Combined with histological data, the results suggest that pulsed IR stimulation does not lead to detectable acute tissue damage and validate the stimulation parameters that can be used in future chronic implants based on pulsed IR...
  11. ncbi Surgical aspects of cochlear implantation: mechanisms of insertional trauma
    Peter S Roland
    Department of Otolaryngology, Head and Neck Surgery, University of Texas Southwestern Medical Center, USA
    Adv Otorhinolaryngol 64:11-30. 2006
    ....
  12. ncbi Speech recognition in noise for cochlear implantees with a two-microphone monaural adaptive noise reduction system
    J Wouters
    Lab. Exp. ORL, K.U. Leuven, Belgium
    Ear Hear 22:420-30. 2001
    ..Taken together, these data demonstrate that cochlear implantees may increase their speech intelligibility in noisy environments with the use of multimicrophone noise reduction systems...
  13. pmc Epilogue: factors contributing to long-term outcomes of cochlear implantation in early childhood
    Ann E Geers
    Dallas Cochlear Implant Program, Callier Advanced Hearing Research Center, The University of Texas at Dallas, Dallas, Texas 75235, USA
    Ear Hear 32:84S-92S. 2011
    ....
  14. pmc Implications of minimizing trauma during conventional cochlear implantation
    Matthew L Carlson
    Department of Otolaryngology Head and Neck Surgery, Mayo Clinic School of Medicine, Rochester, Minnesota 55905, USA
    Otol Neurotol 32:962-8. 2011
    ..between implantation-associated trauma and postoperative speech perception scores among adult and pediatric patients undergoing cochlear implantation using conventional length electrodes and minimally traumatic surgical techniques.
  15. ncbi Cochlear implant programming
    William H Shapiro
    Department of Otolaryngology, NYU Langone Medical Center, 550 First Avenue, New York, NY 10016, USA
    Otolaryngol Clin North Am 45:111-27. 2012
    ..The chapter also provides what the authors believe the future may hold for new programming techniques...
  16. pmc Analysis of the impact of professional involvement in evidence generation for the HTA Process, subproject "cochlear implants": methodology, results and recommendations
    S Berrettini
    Operative Unit of Otorhinolaryngology, Audiology and Phoniatrics, University of Pisa, Italy
    Acta Otorhinolaryngol Ital 31:273-80. 2011
    ..These recommendations have also been evaluated by the Consulting Committee members and approved with minimal suggestions...
  17. pmc Developmental neuroplasticity after cochlear implantation
    Andrej Kral
    Institute of Audioneurotechnology and Department of Experimental Otology, ENT Clinics, Medical University Hannover, Germany
    Trends Neurosci 35:111-22. 2012
    ..review, we discuss the existence of time limits for, and mechanistic constraints on, sensitive periods for cochlear implantation and describe the effects of multimodal and cognitive reorganization that result from long-term auditory ..
  18. ncbi Preservation of residual hearing with cochlear implantation: how and why
    Chris James
    Service ORL, Hopital Purpan, FR 31059 Toulouse, France
    Acta Otolaryngol 125:481-91. 2005
    ..Residual hearing combined with electrical stimulation in the same ear can provide additional benefits even for conventional candidates for cochlear implantation.
  19. ncbi Cortical activity at rest predicts cochlear implantation outcome
    Hyo Jeong Lee
    Department of Otolaryngology, Seoul National University College of Medicine, Seoul, Korea
    Cereb Cortex 17:909-17. 2007
    ..In this paper, we sought to determine how brain metabolic activity measured before implantation relates to cochlear implantation outcome, that is, speech perception...
  20. ncbi Preservation of hearing in cochlear implant surgery: advantages of combined electrical and acoustical speech processing
    Bruce J Gantz
    Department of Otolaryngology Head and Neck Surgery, University of Iowa Roy J and Lucille A Carver College of Medicine, The University of Iowa, Iowa City, Iowa, USA
    Laryngoscope 115:796-802. 2005
    ..of preserving residual low-frequency acoustic hearing as those with more residual hearing are selected for cochlear implantation. Surgical strategies used for hearing preservation with a short hybrid cochlear implant are outlined...
  21. ncbi Resprouting and survival of guinea pig cochlear neurons in response to the administration of the neurotrophins brain-derived neurotrophic factor and neurotrophin-3
    Andrew K Wise
    The Bionic Ear Institute, East Melbourne 3002, Australia
    J Comp Neurol 487:147-65. 2005
    ..These findings have significant implications for an improvement in the performance of the cochlear implant and for future therapies to restore hearing to the deaf...
  22. ncbi Advantages of cochlear implantation in prelingual deaf children before 2 years of age when compared with later implantation
    Manuel Manrique
    Department of Otorhinolaryngology, Head and Neck Surgery Division, University of Navarra Hospital and Medical School, Pamplona, Navarra, Spain
    Laryngoscope 114:1462-9. 2004
    ..To analyze the complications that arose during, or as a result of, the implantation process in these groups...
  23. ncbi Speech perception with mono- and quadrupolar electrode configurations: a crossover study
    Lucas H M Mens
    KNO Audiology, University Medical Center Nijmegen, Nijmegen, The Netherlands
    Otol Neurotol 26:957-64. 2005
    ..To study the effect of two multipolar electrode configurations on speech perception, pitch perception, and the intracochlear electrical field...
  24. pmc Anatomy of the round window and hook region of the cochlea with implications for cochlear implantation and other endocochlear surgical procedures
    Peter M M C Li
    Department of Otology and Laryngology, Harvard Medical School Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Otol Neurotol 28:641-8. 2007
    ..The goal of this study was to create a three-dimensional model of the anatomy of the hook region to identify the optimal site for cochleostomy in cochlear implant surgery...
  25. ncbi [Image-guided minimal-invasive cochlear implantation--experiments on cadavers]
    O Majdani
    HNO Klinik der Medizinischen Hochschule Hannover, Hannover
    Laryngorhinootologie 87:18-22. 2008
    ..A navigation-guided minimally-invasive cochleostomy places highest requirements on the accuracy of intraoperative navigation...
  26. ncbi The development of auditory skills in infants with isolated Large Vestibular Aqueduct Syndrome after cochlear implantation
    Xueqing Chen
    Key laboratory of Otolaryngology Head and Neck Surgery Ministry of Education, Beijing Institute of Otolaryngology, Beijing 100005, China
    Int J Pediatr Otorhinolaryngol 75:943-7. 2011
    ..the auditory performance of infants with isolated Large Vestibular Aqueduct Syndrome (LVAS) after cochlear implantation, compare their performance with those of infants with a normal inner ear, and establish a database of ..
  27. pmc Achievement of hearing preservation in the presence of an electrode covering the residual hearing region
    Shin ichi Usami
    Department of Otorhinolaryngology, Shinshu University School of Medicine, Matsumoto, Japan
    Acta Otolaryngol 131:405-12. 2011
    ..With full insertion with a long electrode, hearing preservation can be achieved even in the presence of a long electrode covering the residual hearing region...
  28. ncbi The effectiveness of bilateral cochlear implants for severe-to-profound deafness in children: a systematic review
    Marloes Sparreboom
    Department of Otorhinolaryngology, Head and Neck Surgery, Radboud University Nijmegen Medical Centre, Donders Institute for Brain, Cognition and Behaviour, Nijmegen, The Netherlands
    Otol Neurotol 31:1062-71. 2010
    To assess the clinical effectiveness of bilateral cochlear implantation compared with unilateral cochlear implantation alone or with a contralateral hearing aid (bimodal stimulation), in children with severe-to-profound hearing loss...
  29. pmc Bilateral cochlear implantation in the ferret: a novel animal model for behavioral studies
    Douglas E H Hartley
    Department of Physiology, Anatomy and Genetics, Oxford OX1 3PT, UK
    J Neurosci Methods 190:214-28. 2010
    Bilateral cochlear implantation has recently been introduced with the aim of improving both speech perception in background noise and sound localization...
  30. ncbi A self-developed and constructed robot for minimally invasive cochlear implantation
    Brett Bell
    ARTORG Center, University of Bern, Switzerland
    Acta Otolaryngol 132:355-60. 2012
    A robot built specifically for stereotactic cochlear implantation provides equal or better accuracy levels together with a better integration into a clinical environment, when compared with existing approaches based on industrial robots.
  31. ncbi Preservation of residual hearing following cochlear implantation: comparison between three surgical techniques
    S Berrettini
    Division of ENT, Department of Neuroscience, University of Pisa, Italy
    J Laryngol Otol 122:246-52. 2008
    ..study of the conservation of residual hearing in three different groups of patients who had undergone cochlear implantation using three different cochlear implant electrode arrays, combined with three different surgical techniques ..
  32. ncbi Reliability of a rating scale for measuring speech intelligibility after pediatric cochlear implantation
    C Allen
    Department of Otolaryngology, University Hospital, Queen's Medical Centre, Nottingham, UK
    Otol Neurotol 22:631-3. 2001
    ..SETTING: Pediatric tertiary referral center for cochlear implantation. PATIENTS AND METHODS: Fifty-four children were each rated by two speech and language therapists, one ..
  33. ncbi A minimally invasive approach for cochlear implantation using a microendoscope
    Harukazu Hiraumi
    Department of Otolaryngology, Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kawaharacho 54, Shogoin, Sakyo ku, Kyoto 606 8507, Japan
    Eur Arch Otorhinolaryngol 270:477-81. 2013
    Given the growing need for minimally invasive approaches to cochlear implantation surgery, we chose to examine the safety of a microendoscopic procedure for cochlear implantation...
  34. pmc Round window versus cochleostomy technique in cochlear implantation: histologic findings
    Celine Richard
    House Research Institute, Los Angeles, California, USA
    Otol Neurotol 33:1181-7. 2012
    ....
  35. ncbi Tinnitus before and 6 months after cochlear implantation
    Martin Kompis
    Department of ENT, Head and Neck Surgery, Inselspital, University of Bern, Switzerland
    Audiol Neurootol 17:161-8. 2012
    ..We found no correlation between tinnitus improvement, age, duration of tinnitus, or change in unaided hearing thresholds between the two sessions...
  36. ncbi Cochlear implantation in children with inner ear malformations
    Lee Suk Kim
    Department of Otolaryngology Head and Neck Surgery, College of Medicine, Dong A University, Busan, Korea
    Ann Otol Rhinol Laryngol 115:205-14. 2006
    The aim of this study was to assess the outcomes of cochlear implantation in children with inner ear malformations (IEMs).
  37. ncbi The role of preoperative, intratympanic glucocorticoids for hearing preservation in cochlear implantation: a prospective clinical study
    Gunesh P Rajan
    Otolaryngology, Head and Neck Surgery Division, School of Surgery, Fremantle Hospital Campus, University of Western Australia, Fremantle, Australia
    Laryngoscope 122:190-5. 2012
    Hearing Preservation is becoming increasingly important in cochlear implantation as there is growing evidence that preserving the residual hearing, especially in the low frequencies in combination with the electric stimulation can ..
  38. ncbi Cochlear implantation assisted by noninvasive image guidance
    Nozomu Matsumoto
    Department of Otorhinolaryngology, Graduate School of Medical Sciences, Kyushu University, Fukuoka Japan
    Otol Neurotol 33:1333-8. 2012
    ..We investigated the benefit and potential drawback of our new method in clinical application and tested the feasibility of routine image-guided surgery...
  39. ncbi Cochlear implantation in children younger than 12 months
    Susan B Waltzman
    Department of Otolaryngology, New York University School of Medicine, New York, New York, USA
    Pediatrics 116:e487-93. 2005
    ..This affords the opportunity to provide these children access to cochlear implantation, although medical and audiologic challenges must be addressed...
  40. pmc Auditory cortex phase locking to amplitude-modulated cochlear implant pulse trains
    John C Middlebrooks
    Kresge Hearing Research Institute, Department of Otolaryngology Head and Neck Surgery, University of Michigan, Ann Arbor, Michigan, USA
    J Neurophysiol 100:76-91. 2008
    ..The results show that cortical neurons can phase lock to modulated electrical pulse trains across the range of modulation frequencies and depths presented by cochlear implant speech processors...
  41. ncbi Minimally invasive computer-assisted approach for cochlear implantation: a human temporal bone study
    Yann Nguyen
    INSERM, UMR S 867, Paris, France
    Surg Innov 18:259-67. 2011
    ..76 mm on the target in all cases. The CAS system with fiducial markers yielded sufficient precision to allow a minimally invasive approach to the cochlea...
  42. ncbi Conservation of residual acoustic hearing after cochlear implantation
    Thomas J Balkany
    Department of Otolaryngology, University of Miami Ear Institute, Miller School of Medicine, Miami, Florida 33101, USA
    Otol Neurotol 27:1083-8. 2006
    This study was designed to test the hypothesis that partial hearing conservation is attainable after cochlear implantation with a long perimodiolar electrode...
  43. pmc Massively parallel DNA sequencing successfully identifies new causative mutations in deafness genes in patients with cochlear implantation and EAS
    Maiko Miyagawa
    Department of Otorhinolaryngology, Shinshu University School of Medicine, Matsumoto, Japan
    PLoS ONE 8:e75793. 2013
    ..factors, the most common etiology in severe to profound hearing loss, are one of the key determinants of Cochlear Implantation (CI) and Electric Acoustic Stimulation (EAS) outcomes...
  44. ncbi Visual stimuli can impair auditory processing in cochlear implant users
    Francois Champoux
    Centre de Recherche en Neuropsychologie et Cognition, Universite de Montreal, Montreal, Quebec, Canada
    Neuropsychologia 47:17-22. 2009
    ..These findings raise several questions with regards to the rehabilitation of cochlear implant users...
  45. ncbi The effects of age at cochlear implantation and hearing aid trial on auditory performance of Chinese infants
    Xueqing Chen
    Key laboratory of Otolaryngology Head and Neck Surgery Ministry of Education, Beijing Institute of Otolaryngology, Beijing 100005, China
    Acta Otolaryngol 130:263-70. 2010
    ..Infants undergoing hearing aid trial and habilitation demonstrated a significant positive effect on the development of auditory skills in comparison with infants without trial and habilitation...
  46. pmc Foreign body or hypersensitivity granuloma of the inner ear after cochlear implantation: one possible cause of a soft failure?
    Joseph B Nadol
    Department of Otology and Laryngology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, Massachusetts 02114, USA
    Otol Neurotol 29:1076-84. 2008
    A tissue response in the form of foreign body or a hypersensitivity reaction to cochlear implantation is common and may be one possible cause of a soft failure of cochlear implantation.
  47. ncbi Facial nerve paralysis following cochlear implant surgery
    Jose N Fayad
    Department of Otolarynology Head and Neck Surgery, Columbia University College of Physicians and Surgeons, The New York Presbyterian Hospital, New York, New York 10021, USA
    Laryngoscope 113:1344-6. 2003
    ..Facial nerve paralysis is a rare but devastating complication of cochlear implant surgery. The aims of the study were to define the incidence of facial nerve paralysis in our series and understand possible mechanisms of injury...
  48. ncbi Combining acoustic and electrical speech processing: Iowa/Nucleus hybrid implant
    Bruce J Gantz
    Department of Otolaryngology Head and Neck Surgery, University of Iowa, Iowa City, IA 52242 1078, USA
    Acta Otolaryngol 124:344-7. 2004
    ..In addition, we test whether residual hearing can be preserved when an electrode is placed up to 10 mm into the inner ear, and whether the site of electrical stimulation influences speech perception...
  49. ncbi Vestibular dysfunction after cochlear implantation
    Manuela Fina
    Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, Campus Box 8115, 660 S Euclid Ave St Louis, MO 63110, USA
    Otol Neurotol 24:234-42; discussion 242. 2003
    To determine the prevalence, symptom characteristics, and potential risk factors for vestibular symptoms after cochlear implantation.
  50. ncbi Functional plasticity of language-related brain areas after cochlear implantation
    A L Giraud
    Wellcome Department of Cognitive Neurology, The Functional Imaging Laboratory, Institute of Neurology, The Royal National ENT Hospital, London, UK
    Brain 124:1307-16. 2001
    ....
  51. pmc Cochlear infrastructure for electrical hearing
    Bryan E Pfingst
    Department of Otolaryngology, Kresge Hearing Research Institute, University of Michigan, 1150 West Medical Center Drive, Ann Arbor, MI 48109 5616, USA
    Hear Res 281:65-73. 2011
    ..Results of these studies support the efforts to improve the biological infrastructure in the implanted ear and guide strategies which optimize stimulation patterns to match patient-specific conditions in the cochlea...
  52. ncbi Quality-of-life benefit from cochlear implantation in the elderly
    Katrien Vermeire
    Department of Otorhinolaryngology and Communication Disorders, University Hospital of Antwerp, Antwerp, Belgium
    Otol Neurotol 26:188-95. 2005
    ..results of geriatric patients receiving cochlear implants with younger age groups and to evaluate the quality of life after cochlear implantation in the geriatric population by means of validated quality-of-life questionnaires.
  53. ncbi Hearing preservation in partial deafness treatment
    Henryk Skarzynski
    International Center of Hearing and Speech of the Institute of Physiology and Pathology of Hearing, Warsaw Kajetany, Poland
    Med Sci Monit 16:CR555-62. 2010
    ..Possible solutions include acoustic methods only, the use of hearing aids or middle ear implants, electric complementation, and a combination of electric and acoustic stimulation...
  54. pmc Music perception in cochlear implant users and its relationship with psychophysical capabilities
    Ward R Drennan
    V M Bloedel Hearing Research Center, Department of Otolaryngology, University of Washington, Seattle, WA 98195, USA
    J Rehabil Res Dev 45:779-89. 2008
    ..If successful, these approaches could improve the quality of life for implantees by improving communication and musical and environmental awareness...
  55. pmc Effects of training on recognition of musical instruments presented through cochlear implant simulations
    Virginia D Driscoll
    Iowa Cochlear Implant Clinical Research Center, University of Iowa Hospital and Clinics, USA
    J Am Acad Audiol 20:71-82. 2009
    ..The simulation of the CI (cochlear implant) signal presents a degraded representation of each musical instrument, which makes recognition difficult...
  56. ncbi Congenital malformation of the inner ear and pediatric cochlear implantation
    Emmanuel A M Mylanus
    Department Otorhinolaryngology, University Medical Center, Nijmegen, The Netherlands
    Otol Neurotol 25:308-17. 2004
    To study the surgical aspects and performance outcome of cochlear implantation in children with malformed inner ears.
  57. ncbi Evaluation of evoked potentials to dyadic tones after cochlear implantation
    Pascale Sandmann
    Institute of Psychology, Division of Neuropsychology, University of Zurich, Switzerland
    Brain 132:1967-79. 2009
    ..of auditory evoked potentials are of major relevance to understanding auditory cortex function after cochlear implantation and could be of substantial clinical value by indicating the maturation/reorganization of the auditory ..
  58. ncbi Cochlear implantation in patients with neurofibromatosis type 2 and bilateral vestibular schwannoma
    Lawrence R Lustig
    Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins University, Baltimore, Maryland, and Department of Otolaryngology Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota, USA
    Otol Neurotol 27:512-8. 2006
    To investigate the results of cochlear implantation in patients with neurofibromatosis Type 2 (NF2) and bilateral vestibular schwannoma.
  59. ncbi A true minimally invasive approach for cochlear implantation: high accuracy in cranial base navigation through flat-panel-based volume computed tomography
    Omid Majdani
    Department of Otolaryngology, Medical University of Hannover, Hannover, Germany
    Otol Neurotol 29:120-3. 2008
    ..With such an approach, surgical time and expertise may be reduced, and hearing preservation may be improved...
  60. pmc Mismatch negativity and adaptation measures of the late auditory evoked potential in cochlear implant users
    Fawen Zhang
    Department of Communication Sciences and Disorders, University of Cincinnati, OH, USA
    Hear Res 275:17-29. 2011
    ..The abnormal electrophysiological findings in moderate-to-poor performers suggest that long-term deafness may cause damage not only at the auditory cortical level, but also at the cognitive level...
  61. pmc Cochlear-implant high pulse rate and narrow electrode configuration impair transmission of temporal information to the auditory cortex
    John C Middlebrooks
    Department of Otolaryngology Head and Neck Surgery, Kresge Hearing Research Institute, University of Michigan, Ann Arbor, Michigan, USA
    J Neurophysiol 100:92-107. 2008
    ..Results from this animal model suggest explanations for the failure of high pulse rates and/or bipolar electrode configurations to produce hoped-for improvements in speech reception...
  62. ncbi Imaging plasticity in cochlear implant patients
    A L Giraud
    Physiology Department, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Audiol Neurootol 6:381-93. 2001
    ..to human studies of plasticity, we discuss the different forms of plasticity that are associated with cochlear implantation and we point to the interest of imaging studies for providing a prognosis of functional outcome after ..
  63. ncbi Uncovering auditory evoked potentials from cochlear implant users with independent component analysis
    Filipa C Viola
    Neuropsychology Lab, Department of Psychology, University of Oldenburg, Germany
    Psychophysiology 48:1470-80. 2011
    ..95) that were previously contaminated with CI artifacts. The results confirm that after ICA, good quality AEPs can be recovered, facilitating the objective, noninvasive study of auditory cortex function in CI users...
  64. ncbi Intensity discrimination and detection of amplitude modulation in electric hearing
    G S Donaldson
    Department of Otolaryngology, University of Minnesota, Minneapolis 55455, USA
    J Acoust Soc Am 108:760-3. 2000
    ..It can be shown that the absence of compression in electric hearing does not preclude this possibility...
  65. pmc Changes in the tinnitus handicap questionnaire after cochlear implantation
    Tao Pan
    Department of Otolaryngology, University of Iowa, 200 Hawkins Drive, Iowa City, IA 52242 1009, USA
    Am J Audiol 18:144-51. 2009
    ....
  66. ncbi Cochlear implantation in inner ear malformations--a review article
    Levent Sennaroglu
    Department of Otolaryngology, Hacettepe University Medical Faculty, Sihhiye, Ankara, Turkey
    Cochlear Implants Int 11:4-41. 2010
    ..Finally meningitis which may occur with and without cochlear implantation in this special group of patients is emphasized...
  67. ncbi Longitudinal changes in children's speech and voice physiology after cochlear implantation
    Maureen B Higgins
    Boys Town National Research Hospital, Omaha, Nebraska, USA
    Ear Hear 24:48-70. 2003
    ..to describe speech/voice physiological characteristics of prelingually deafened children before and after cochlear implantation and determine whether they fall into a range that would be considered deviant, 2) to determine whether ..
  68. ncbi Source localization of auditory evoked potentials after cochlear implantation
    Stefan Debener
    MRC Institute of Hearing Research Southampton, Southampton, UK
    Psychophysiology 45:20-4. 2008
    ..In contrast to normal hearing individuals, the man with the CI showed a 20-ms shorter N1 latency ipsilaterally. We conclude that ICA allows the detailed study of AEPs in CI users...
  69. pmc Detection and rate discrimination of amplitude modulation in electrical hearing
    Monita Chatterjee
    Cochlear Implants and Psychophysics Laboratory, Department of Hearing and Speech Sciences, University of Maryland, College Park, Maryland 20742, USA
    J Acoust Soc Am 130:1567-80. 2011
    ..Overall, results indicated that intensity cues did not play an important role in temporal envelope processing by the average CI listener...
  70. ncbi Does brain activity at rest reflect adaptive strategies? Evidence from speech processing after cochlear implantation
    K Strelnikov
    Universite Toulouse, CerCo, Universite Paul Sabatier, 31062 Toulouse, France
    Cereb Cortex 20:1217-22. 2010
    ..of auditory experience, such as profound deafness followed by partial auditory recuperation through cochlear implantation, leads to functional cortical reorganizations at rest...
  71. pmc Cochlear implantation in the very young child: issues unique to the under-1 population
    Maura Cosetti
    New York University, New York, NY, USA
    Trends Amplif 14:46-57. 2010
    Since the advent of cochlear implantation, candidacy criteria have slowly broadened to include increasingly younger patients...
  72. ncbi Cochlear implantation in the very young child: Long-term safety and efficacy
    J Thomas Roland
    Department of Otolaryngology, New York University Langone Medical Center, New York, New York, USA
    Laryngoscope 119:2205-10. 2009
    ..tools allowing more definitive diagnosis of profound sensorineural hearing loss in young children, cochlear implantation in children <12 months of age is now common...
  73. doi Editorial: 'auditory neuropathy' and cochlear implantation - myths and facts
    William P R Gibson
    Cochlear Implants Int 9:1-7. 2008
    ..Rather than continuing to use a blanket and often misleading term, we are now in a better position to describe each individual case exhibiting this phenomenon according to the correct site of lesion...
  74. ncbi Incapacitating unilateral tinnitus in single-sided deafness treated by cochlear implantation
    Paul Van de Heyning
    Department of Otorhinolaryngology Head and Neck Surgery, University Hospital Antwerp, University of Antwerp, Antwerp, Belgium
    Ann Otol Rhinol Laryngol 117:645-52. 2008
    ..This study assessed the effect of electrical stimulation via a CI on tinnitus in subjects with unilateral deafness and ipsilateral tinnitus who underwent implantation in an attempt to treat tinnitus with the CI...
  75. ncbi The effects of unilateral cochlear implantation on the tinnitus handicap inventory and the influence on quality of life
    Hosam A Amoodi
    Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    Laryngoscope 121:1536-40. 2011
    b>Cochlear implantation is now the standard of care in patients with significant sensorineural hearing loss. It is well known that patients with severe hearing loss also experience disabling tinnitus...
  76. pmc Role of electrode placement as a contributor to variability in cochlear implant outcomes
    Charles C Finley
    Departments of Otolaryngology Head and Neck Surgery and Biomedical Engineering, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Otol Neurotol 29:920-8. 2008
    ..Suboptimal cochlear implant (CI) electrode array placement may reduce presentation of coded information to the central nervous system and, consequently, limit speech recognition...
  77. ncbi Subjective and objective results after bilateral cochlear implantation in adults
    Roman D Laske
    Department of Otorhinolaryngology, Head and Neck Surgery, University Hospital of Zurich, Switzerland
    Otol Neurotol 30:313-8. 2009
    To assess and compare subjective and objective results after bilateral cochlear implantation with a special emphasis on time interval between the first and second implant.
  78. ncbi Hearing preservation in cochlear implantation for electric acoustic stimulation
    Wolfgang Gstoettner
    ENT Department, Head and Neck Surgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Otolaryngol 124:348-52. 2004
    ..To evaluate the possibility of preservation of low-frequency hearing in atraumatic cochlear implant electrode insertion procedures for combined, ipsilateral electric and acoustic stimulation...
  79. pmc Music perception with cochlear implants: a review
    Hugh J McDermott
    Department of Otolaryngology, The University of Melbourne, Melbourne, Australia
    Trends Amplif 8:49-82. 2004
    The acceptance of cochlear implantation as an effective and safe treatment for deafness has increased steadily over the past quarter century...
  80. ncbi Cross-modal plasticity underpins language recovery after cochlear implantation
    A L Giraud
    Department of Physiology and, Johann Wolfgang Goethe University, 60590 am Main, Frankfurt, Germany
    Neuron 30:657-63. 2001
    Postlingually deaf subjects learn the meaning of sounds after cochlear implantation by forming new associations between sounds and their sources...
  81. pmc Neurotrophic factor intervention restores auditory function in deafened animals
    Takayuki Shinohara
    Institute for Hearing and Communication Research and Department of Clinical Neuroscience, Karolinska Institutet, SE 171 76 Stockholm, Sweden
    Proc Natl Acad Sci U S A 99:1657-60. 2002
    ..The findings have direct implications for the enhancement of responsiveness in deafferented peripheral nerves...
  82. pmc Measures of working memory span and verbal rehearsal speed in deaf children after cochlear implantation
    David B Pisoni
    Indiana University School of Medicine, Department of Otolaryngology Head and Neck Surgery, Indianopolis, Indiana 46202, USA
    Ear Hear 24:106S-20S. 2003
    Large individual differences in spoken word recognition performance have been found in deaf children after cochlear implantation. Recently, Pisoni and Geers (2000) reported that simple forward digit span measures of verbal working memory ..
  83. ncbi A model for cochlear implant electrode insertion and force evaluation: results with a new electrode design and insertion technique
    J Thomas Roland
    Department of Otolaryngology and Neurosurgery, New York University School of Medicine, 550 First Avenue, New York, NY 10016, U S A
    Laryngoscope 115:1325-39. 2005
    ..In addition, this study should serve to present a novel model for cochlear implant electrode insertion evaluations...
  84. ncbi Effects of congenital hearing loss and cochlear implantation on audiovisual speech perception in infants and children
    Tonya R Bergeson
    Department of Otolaryngology Head and Neck Surgery, Indiana University School of Medicine, Indiana, IN 46202, USA
    Restor Neurol Neurosci 28:157-65. 2010
    b>Cochlear implantation has recently become available as an intervention strategy for young children with profound hearing impairment...
  85. ncbi Cochleostomy site: implications for electrode placement and hearing preservation
    Robert J S Briggs
    CRC for Cochlear Implant and Hearing Aid Innovation, Melbourne, Victoria, Australia
    Acta Otolaryngol 125:870-6. 2005
    With recent increased interest in minimizing intracochlear trauma and preserving residual hearing during cochlear implantation, increased attention must be paid to the cochleostomy site...
  86. ncbi Predictive models for cochlear implantation in elderly candidates
    Janice Leung
    Division of Otology, Neurotology, and Skull Base Surgery, Department of Otolaryngology Head and Neck Surgery, The Johns Hopkins Hospital, Baltimore, MD 21287, USA
    Arch Otolaryngol Head Neck Surg 131:1049-54. 2005
    ..An aging American population carries a high prevalence of profound sensorineural hearing loss. We examined the performance of multichannel cochlear implant recipients in a large database of adult subjects...
  87. ncbi Horizontal-plane localization of noise and speech signals by postlingually deafened adults fitted with bilateral cochlear implants
    D Wesley Grantham
    Vanderbilt Bill Wilkerson Center for Otolaryngology and Communication Sciences, Vanderbilt University Medical Center, Nashville, TN 37232 8242, USA
    Ear Hear 28:524-41. 2007
    ..A third objective was to evaluate the relative roles of interaural level difference (ILD) and interaural temporal difference (ITD) cues in localization by these subjects...
  88. ncbi Effect of age at cochlear implantation on auditory skill development in infants and toddlers
    Amy McConkey Robbins
    Communication Consulting Services, Indianapolis, IN 46260, USA
    Arch Otolaryngol Head Neck Surg 130:570-4. 2004
    To investigate the effect of age at cochlear implantation on the auditory development of children younger than 3 years and to compare these children's auditory development with that of peers with normal hearing.
  89. ncbi Childhood Development after Cochlear Implantation (CDaCI) study: design and baseline characteristics
    Nancy E Fink
    Johns Hopkins University, Baltimore, MD 21205, USA
    Cochlear Implants Int 8:92-116. 2007
    ..The Childhood Development after Cochlear Implantation (CDaCI) study is the first longitudinal multicentre, national cohort study to evaluate systematically ..
  90. ncbi Bilateral cochlear implants: a way to optimize auditory perception abilities in deaf children?
    H Kühn-Inacker
    Center for Hearing Impaired Children, Wurzburg, Germany
    Int J Pediatr Otorhinolaryngol 68:1257-66. 2004
    ..In this study, the auditory skills of children using bilateral cochlear implants were evaluated...
  91. ncbi Cochlear implantation in children with anomalous cochleovestibular anatomy
    Blake C Papsin
    Department of Otolaryngology, The Hospital for Sick Children, Toronto, Ontario, Canada
    Laryngoscope 115:1-26. 2005
    To evaluate outcomes after cochlear implantation in children with anomalous cochleovestibular anatomy, a review of radiological classification, surgical implantation, and outcome of 103 children with such anomalies was performed...
  92. ncbi Binaural cochlear implants placed during the same operation
    Bruce J Gantz
    Department of Otolaryngology Head and Neck Surgery, University of Iowa College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa 52242 1078, USA
    Otol Neurotol 23:169-80. 2002
    ....
  93. ncbi Successful cochlear implantation in a patient with MNGIE syndrome
    Jia nan Li
    Department of Otolaryngology Head and Neck Surgery, Institute of Otolaryngology, Chinese PLA General Hospital, Beijing, PR China
    Acta Otolaryngol 131:1012-6. 2011
    ..neurogastrointestinal encephalomyopathy (MNGIE syndrome) undergoing evaluation for multichannel cochlear implantation is described...
  94. ncbi Outcomes in cochlear implantation: variables affecting performance in adults and children
    Maura K Cosetti
    Department of Otolaryngology, New York University School of Medicine, 550 First Avenue, Suite 7Q, New York, NY 10016, USA
    Otolaryngol Clin North Am 45:155-71. 2012
    ..Research on the outcomes following cochlear implantation has identified a wide spectrum of variables known to affect pos0timplantation performance...
  95. ncbi Cochlear implantation in children with keratitis-ichthyosis-deafness (KID) syndrome: outcomes in three cases
    Elizabeth J Barker
    Department of Otolaryngology, The University of Melbourne, The Royal Victorian Eye and Ear Hospital, Melbourne, Australia
    Cochlear Implants Int 10:166-73. 2009
    ..The tendency to eczematous dermatitis and otitis media is an additional problem with cochlear implantation. All cases have required additional medical management, however the outcomes show that the cochlear ..
  96. ncbi Effects of stimulation rate with the Nucleus 24 ACE speech coding strategy
    Laura K Holden
    Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Ear Hear 23:463-76. 2002
    ....
  97. ncbi Implication of central asymmetry in speech processing on selecting the ear for cochlear implantation
    Luc G Morris
    Department of Otolaryngology and Cochlear Implant Center, New York University School of Medicine, New York, New York 10016, USA
    Otol Neurotol 28:25-30. 2007
    ..The purpose of this study is to determine if this central asymmetry in speech processing has implications for selecting the ear for cochlear implantation.
  98. ncbi Taste changes in patients who underwent cochlear implantation by the nonmastoidectomy approach
    Lela Migirov
    Department of Otolaryngology and Head and Neck Surgery, Sheba Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Hashomer, Israel
    ORL J Otorhinolaryngol Relat Spec 71:66-9. 2009
    To describe taste changes following a nonmastoidectomy approach to cochlear implantation (CI).
  99. pmc Behavioral assessment of prelingually deaf children before cochlear implantation
    David L Horn
    DeVault Otologic Research Laboratory, Department of Otolaryngology Head and Neck Surgery, Indiana University School of Medicine, 699 Riley Research Wing 044, Indianapolis, IN 46202, USA
    Laryngoscope 115:1603-11. 2005
    ..To determine whether scores from a behavioral assessment of prelingually deafened children who present for cochlear implant surgery are predictive of audiological outcomes...
  100. ncbi Surgical results of cochlear implantation in malformed cochlea
    Levent Sennaroglu
    Department of Otolaryngology Head and Neck Surgery, Hacettepe University, Ankara, Turkey
    Otol Neurotol 27:615-23. 2006
    To report the surgical aspects of cochlear implantation in malformed cochlea.
  101. ncbi Cochlear implantation in postirradiated ears: outcomes and challenges
    Wong Kein Low
    Department of Otolaryngology, Singapore General Hospital, Singapore
    Laryngoscope 116:1258-62. 2006
    Radiotherapy to head and neck tumors can potentially damage the auditory pathways. This has relevance in cochlear implants and there is a need for clinical studies to confirm the feasibility of cochlear implantation in these patients.

Research Grants64

  1. Bilateral cochlear implants: Physiology and psychophysics
    Bertrand Delgutte; Fiscal Year: 2012
    DESCRIPTION (provided by applicant): Bilateral cochlear implantation aims at restoring the functional benefits of binaural hearing to the profoundly deaf...
  2. Effectiveness of Therapy via Telemedicine following Cochlear Implants
    Anu Sharma; Fiscal Year: 2013
    ..Many of them are candidates for cochlear implantation (CI), which involves surgical placement of an electronic device in one or both ears...
  3. Hearing Loss and Aging
    Frank R Lin; Fiscal Year: 2013
    ..conceptual models of functioning developed by the World Health Organization to the assessment of pediatric cochlear implantation (CI). With the support of this Mentored Career Development Award, Dr...
  4. Pediatric Percutaneous Cochlear Implantation Clinical Validation &Implementation
    Robert F Labadie; Fiscal Year: 2012
    ..our ongoing, NIH-funded adult project (R01 DC008408), we have demonstrated the feasibility of percutaneous cochlear implantation (PCI). PCI reduces CI surgery to a single pass of a drill from the lateral skull base to the cochlea...
  5. Microscopy in the cochlea
    Mark J Schnitzer; Fiscal Year: 2011
    ..within the human cochlea would be a tremendous boon both for clinicians seeking surgical guidance during cochlear implantation or other otologic procedures, as well as for basic researchers seeking to correlate cellular ..
  6. SCORE: Principal Differential Analysis with Covariates for Functional Data
    Joan G Staniswalis; Fiscal Year: 2012
    ..changes in temporal processing of auditory stimuli, and better prediction of clinical outcomes from cochlear implantation. The methods have the potential to be used for the early detection of traumatic brain injury (TBI)...
  7. Sustained Release Inner Ear Delivery of Corticosteroid
    William H Slattery; Fiscal Year: 2011
    ..The goal of this project is to develop a steroid eluting cochlear implant. Currently, cochlear implantation leads to loss of residual hearing and the procedure is therefore reserved for the profoundly deaf...
  8. Clinical Validation and Testing of Percutaneous Cochlear Implantation
    Robert F Labadie; Fiscal Year: 2013
    ..In our ongoing NIH-funded project (R01 DC008408), we have demonstrated the feasibility of percutaneous cochlear implantation (PCI). PCI reduces CI surgery to a single pass of a drill from the lateral skull surface to the cochlea...
  9. The relationship of hearing loss to maternal CMV immune status in infants with co
    Gail J Demmler; Fiscal Year: 2011
    ..of sensorineural loss in the mid frequency (up to 4,000 Hz) range;describe the prevalence and outcome of cochlear implantation as a treatment for deafness due to cCMV infection;and to evaluate the positive and negative experiences of ..
  10. Outcomes in Children with Developmental Delay and Deafness: a Randomized Trial
    John S Oghalai; Fiscal Year: 2013
    ..Currently, there is little compelling evidence supporting the idea that cochlear implantation provides benefit to children that don't have the cognitive potential to develop normal speech and ..
  11. EFFECTS OF ASYMMETRIC HEARING IN ACOUSTIC LISTENERS AND COCHLEAR IMPLANT USERS
    Jill B Firszt; Fiscal Year: 2013
    ..In Aim 3, we examine the benefit of cochlear implantation for adults and children with asymmetric hearing loss and varied ages at onset of deafness and hearing ..
  12. OBJECTIVE MEASURES IN AUDITORY IMPLANTS 6TH INTERNATIONAL SYMPOSIUM
    Jill B Firszt; Fiscal Year: 2010
    ..b>Cochlear implantation is currently considered the standard of care for individuals who are deaf, however variability in outcomes ..
  13. Virally Mediated Gene Therapy for Genetic Hearing Loss
    Lawrence R Lustig; Fiscal Year: 2013
    ..of deafness is quite limited, and consists of hearing amplification for mild to severe hearing loss, and cochlear implantation for severe to profound hearing loss...
  14. Conference Grant for symposium entitled "Emerging Issues in Cochlear Implanta
    DONNA L SORKIN; Fiscal Year: 2013
    ..a newly formed not-for-profit organization is convening the CI 2013 Symposium "Emerging Issues in Cochlear Implantation" to share information and promote discussion among attendees with the aim of encouraging needed research, ..
  15. Apparatus for placing electrodes for deep-brain stimulation
    J Michael Fitzpatrick; Fiscal Year: 2012
    ..These applications are quite different, but phantom, cadaveric, and clinical testing of the device for cochlear implantation strongly suggest that the microtable is likely to have the accuracy necessary for DBS as well...
  16. Functions of Associative Auditory Cortical Plasticity
    Norman M Weinberger; Fiscal Year: 2013
    ..remediation of phonological processing deficits in children and learning to comprehend speech following cochlear implantation. The optimal design of remediation training will directly benefit from promoting the desired type of ..
  17. Development of Translational Research to Improve Outcomes for Cochlear Implants
    Paul W Flint; Fiscal Year: 2010
    ..The third project will address preservation of residual hearing with cochlear implantation. As mechanisms for preservation of hearing are identified and tested in animal models, these methodologies ..
  18. ELECTRON MICROSCOPY OF THE HUMAN INNER EAR
    Joseph B Nadol; Fiscal Year: 2013
    ..In addition, the immediate and delayed trauma induced by cochlear implantation is extremely variable and in some cases may be progressive and lead to worsening of the word recognition ..
  19. Hearing Preservation for Noise or Cochlear Implantation: Mechanisms &Treatments
    Richard A Altschuler; Fiscal Year: 2013
    ....
  20. Deaf infants'cognitive skills and their post-cochlear implant language outcomes
    CARISSA LYNN SHAFTO; Fiscal Year: 2013
    ..learning (VSL) in infants aged 8 to 23 months with severe-to-profound deafness that will be undergoing cochlear implantation. Their performance on the VSL task will be compared to the performance of aged-matched infants with NH...
  21. Neurocognitive Processes in Deaf Children with Cochlear Implants
    David B Pisoni; Fiscal Year: 2013
    ..neurocognitive processes underlying speech and language outcomes in prelingually deaf children following cochlear implantation. Past research on cochlear implants has been narrowly focused on speech and language outcomes and efficacy ..
  22. Language, Learning, and Cognition among Deaf Students with and without Cochlear I
    MARC E MARSCHARK; Fiscal Year: 2013
    ..Beyond spoken language and reading abilities of young children, far less is known about outcomes following cochlear implantation, particularly in older deaf children and youth and among those without cochlear implants...
  23. Binaural Unmasking in Children with Cochlear Implants
    Ann E Todd; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Bilateral cochlear implantation in children is becoming increasingly popular in an effort to improve the ability to localize sound sources and understand speech in the presence of interfering stimuli...
  24. THE EFFECTS OF EARLY ACOUSTIC HEARING FOR PEDIATRIC COCHLEAR IMPLANT RECIPIENTS
    LISA SURBER DAVIDSON; Fiscal Year: 2013
    ..These studies will eventually guide clinicians in making informed recommendations regarding early bimodal (HA/CI) use and the timing of potential bilateral cochlear implantation.
  25. Electrically-evoked neural responses in children with auditory neuropathy
    Shuman He; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Cochlear implantation (CI) has been used as a treatment option for children with auditory neuropathy spectrum disorder (ANSD) who do not benefit from conventional hearing aids...
  26. Multisensory Processing: Plasticity & Accommodation to a Sensory Prosthesis
    LYNNE ESTHER BERNSTEIN; Fiscal Year: 2010
    ..methods to investigate multisensory (visual, vibrotactile, and auditory) processing before and after cochlear implantation. Speech and non-speech multisensory perceptual effects will be investigated...
  27. Childhood Development After Cochlear Implantation
    JOHN KIM NIPARKO; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The Childhood Development after Cochlear Implantation (CDaCI) Study is a multisite, prospective investigation of a large and diverse cohort of US children with cochlear implants...
  28. Accurate Localization of General Tubular Structures in Medical Images
    JACK NOBLE; Fiscal Year: 2010
    ..of this project have the potential to provide physicians with anatomical information that will make cochlear implantation safer and a more available treatment for deafness, increase safety and efficiency in the placement of deep ..
  29. 13th Symposium on Cochlear Implants in Children
    Nancy Melinda Young; Fiscal Year: 2011
    ..and advance clinical care, educational practices and technology development in the field of pediatric cochlear implantation. We anticipate significant attendance from North America with approximately 1000 expected delegates...
  30. DEAFNESS AND OSSIFICATION IN LABYRINTHITIS OSSIFICANS
    Hilary Brodie; Fiscal Year: 2004
    ..However, LO can reduce the efficacy of cochlear implantation. The long-term objective of this research program is to understand the mechanisms which lead to the ..
  31. Mapping the Connectivity of Cochlear Nucleus Bushy Cells
    Luke Campagnola; Fiscal Year: 2011
    ..provide a model that is as physiologically accurate as possible, allowing greater insight into tinnitus, cochlear implantation, and auditory processing...
  32. Voice Pitch Processing By Normally-Hearing and Cochlear-Implanted Children
    Monita Chatterjee; Fiscal Year: 2012
    ..these studies will shed important new light on young children's sensitivity to voice pitch cues, how cochlear implantation might influence this sensitivity, and the extent to which the early-implanted auditory system can overcome ..
  33. Acquiring language with a cochlear implant: The role of sequential learning
    CHRISTOPHER CONWAY; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): A critical barrier to progress in the field of cochlear implantation understands the role that fundamental mechanisms of learning and memory play in language outcomes...
  34. Complex pitch perception in very-early implanted children
    Rosalie Uchanski; Fiscal Year: 2007
    ..Because FDA approval was given just 41/2 years ago for cochlear implantation at 12 months of age, it is only now possible to test this hypothesis with a substantial number of children ..
  35. Clinical Application of Spectral Envelope Perception: Cochlear Implant Evaluation
    RENE H GIFFORD; Fiscal Year: 2013
    ..for selecting the er to be implanted-a critical consideration particularly in cases for which bilateral cochlear implantation may be restricted (i.e. insurance restrictions)...
  36. Implicit Sequence Learning in Deaf Children with Cochlear Implants
    CHRISTOPHER CONWAY; Fiscal Year: 2010
    ..in understanding and explaining the enormous variability in outcome and benefit in deaf children following cochlear implantation. The first aim of this project is to determine the extent to which deaf children with cochlear implants (..
  37. Mechanism of Opiate Induced Audiovestibular Dysfunction
    Gail Ishiyama; Fiscal Year: 2006
    ..Profound bilateral deafness requiring cochlear implantation secondary to chronic high dose use of acetaminophen/hydrocodone has been reported by our Neurotology ..
  38. Multimodal Perception by Infants with Cochlear Implants
    Tonya Bergeson Dana; Fiscal Year: 2006
    ..perception skills and visual attention and lip reading skills in hearing-impaired infants before and after cochlear implantation. Eye movement measures that have been successfully developed in research with normal-hearing infants will ..
  39. Phonological Systems of Pediatric Cochlear Implant Users
    Steven Chin; Fiscal Year: 2007
    ..detailed analyses of the phonological systems that underlie speech production by deaf children after cochlear implantation. These detailed linguistic analyses of sound segment inventories, constraints on sequencing, variation in ..
  40. Comparison of bimodal and bilateral cochlear implant users
    HELEN CULLINGTON; Fiscal Year: 2007
    ..Relevance: Bilateral cochlear implantation is expensive, usually involves two surgeries and risks the loss of residual hearing...
  41. CEREBRAL ORGANIZATION FOLLOWING COCHLEAR IMPLANT
    STEPHEN LOMBER; Fiscal Year: 2005
    ..characteristic normal functional cartography of non-primary auditory cortex is established following early cochlear implantation. To accomplish this, we will reversibly deactivate AAF and PAF cortices in the CD cats with cochlear ..
  42. COCHLEAR IMPLANTS AND EDUCATION OF THE DEAF CHILD
    Ann Geers; Fiscal Year: 2000
    ..Assuming that, for a perlingually deaf child, the purpose of cochlear implantation is the achievement of higher levels of spoken English and reading, it is critical to determine the extent ..
  43. FMRI of Pediatric Cochlear Implant Candidates
    Scott Holland; Fiscal Year: 2002
    ..magnetic resonance imaging (fMRI) technology as a tool for evaluation of pediatric candidates for cochlear implantation. FMRI is a relatively new and highly sophisticated technology, which can provide a window into the ..
  44. fMRI, Genes and Outcome for Cochlear Implants in Infants
    Scott Holland; Fiscal Year: 2009
    b>Cochlear implantation (CI) has revolutionized the management of congenitally deaf children...
  45. EIGHTH SYMPOSIUM ON COCHLEAR IMPLANTS IN CHILDREN
    Laurie Eisenberg; Fiscal Year: 2000
    ..clinicians, educators, and technical specialists involved in the many areas that define pediatric cochlear implantation. The field has now matured such that many children have been using multichannel cochlear implants for over ..
  46. Bilateral cochlear implants: improving performance
    Donald Eddington; Fiscal Year: 2009
    ..These advantages are a primary motivation for bilateral cochlear implantation. In this application, experts in cochlear implants and binaural hearing join in an effort to better ..
  47. COCHLEAR IMPLANTS IN CHILDREN
    Richard Miyamoto; Fiscal Year: 1990
    ..in children is designed to bring together researchers and clinicians who are working in the field of cochlear implantation in the deaf pediatric population, as well as scientists from related fields, for exchange of ideas and ..
  48. Cross-modal Plasticity in Prelingually Deaf Children
    Kristi Buckley; Fiscal Year: 2006
    ..One such factor is the age at implantation. Previous research has suggested a sensitive period for cochlear implantation in the prelingually deaf; however, the mechanisms limiting this sensitive period are not understood...
  49. Acoustic and electrical hearing after Math1 treatment
    BRYAN PFINGST; Fiscal Year: 2005
    ..In Aim 3, we will assess the interaction between Ad.Math 1 inoculation, cochlear implantation, and electrical stimulation of the cochlear implant...
  50. Expanded domain of learning-induced primary auditory cortical plasticity
    KATARZYNA BIESZCZAD; Fiscal Year: 2009
    ..studies could be used towards the development of auditory learning therapies for use after artificial cochlear implantation in humans to help acquire higher-level auditory function...
  51. 4TH SYMPOSIUM OF COCHLEAR IMPLANTS IN CHILDREN
    Charles Luetje; Fiscal Year: 1992
    b>Cochlear implantation in children has been performed for ten years. Technological advances have evolved rapidly from single to multichannel devices allowing some deaf children an understanding of the spoken word...
  52. Electo-anatomical Modeling of the Cochlear Implant
    DARREN WHITEN; Fiscal Year: 2004
    ..of this project is to identify the fundamental mechanisms that limit the benefit a patient derives from cochlear implantation. Better treatment of profound hearing loss with a cochlear implant (improved candidacy criteria, patient ..
  53. Long-term Outcomes of Cochlear Implantation in Early Childhood
    Ann Geers; Fiscal Year: 2009
    ..In addition we will document the incidence and outcomes associated with discontinued use of a cochlear implant. ..
  54. MOTOR CONTROL OF SERIAL ORGANIZATION OF EARLY SPEECH
    Peter MacNeilage; Fiscal Year: 2005
    ..3. Speech organization in infants with Multichannel Cochlear Implantation: We will explore the implications for theory, assessment and intervention of the prediction that at ..
  55. PHYSIOLOGY OF VOCALIZATION SEN IN AUDITORY CORTEX
    MARK TRAMO; Fiscal Year: 2002
    ..peripheral disease and to compare cortical neuron responses to vocal communication sounds before and after cochlear implantation. The aim of research on the single-unit physiology of auditory cortex in relation to the psychophysics of ..
  56. Cochlear Implant Research: Present and Future
    BRENDA BATTAT; Fiscal Year: 2003
    ..and development of implanted children; auditory plasticity; the future of CI technology; the criteria for cochlear implantation; and the importance of signal processing and learning in CI...
  57. Selective Attention and Perceptual Learning of Speech
    ALEXANDER FRANCIS; Fiscal Year: 2006
    ..for more clinically oriented studies investigating the re-acquisition of speech perception following cochlear implantation; the role of attention and working memory factors in specific language impairment (SLI), dyslexia, and ..
  58. Long-term Outcomes of Cochlear Implantation in Early Childhood
    Ann Geers; Fiscal Year: 2006
    ..abstract not provided ..
  59. COCHLEAR IMPLANT--AUDITORY FUNCTION & SPEECH PERCEPTION
    Michael Dorman; Fiscal Year: 2009
    ..abstract_text> ..
  60. EARLY VOCAL DEVELOPMENT IN YOUNG CHILDREN WITH COCHLEAR
    DAVID ERTMER; Fiscal Year: 2002
    ..18). ..
  61. Speech Development in Young Cochlear Implant Recipients
    David J Ertmer; Fiscal Year: 2010
    Recent reductions in age requirements for cochlear implantation (currently FDA-approved at 12 months) have made it possible for deaf infants and toddlers to begin to hear at ages when many foundational speech skills are normally ..
  62. Functional Abilities in Children With Bilateral Hearing
    Ruth Litovsky; Fiscal Year: 2005
    ..In addition, the research might provide some insight into situations in which bilateral hearing, with dual CIs, or with a CI/HA combination, should or should not be pursued. ..
  63. Speech Perception by Infants after Cochlear Implantation
    Derek Houston; Fiscal Year: 2007
    ..assessing auditory-perceptual processing skills of deaf infants before and at regular intervals following cochlear implantation. A new laboratory has been constructed at the Indiana University School of Medicine to implement two ..
  64. Image-Guided Otologic Surgery
    Robert Labadie; Fiscal Year: 2004
    ..It is anticipated that this system will make ear surgery safer and more efficient. ..