perioperative care

Summary

Summary: Interventions to provide care prior to, during, and immediately after surgery.

Top Publications

  1. ncbi ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guideline
    Lee A Fleisher
    Society for Vascular Medicine and Biology
    Circulation 116:e418-99. 2007
  2. ncbi Laparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical trial (LAFA-study)
    Malaika S Vlug
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    Ann Surg 254:868-75. 2011
  3. ncbi Predictors of length of stay and patient satisfaction after hip and knee replacement surgery: fast-track experience in 712 patients
    Henrik Husted
    Department of Orthopaedics, Copenhagen University Hospital of Hvidovre, Denmark
    Acta Orthop 79:168-73. 2008
  4. ncbi Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection
    K C H Fearon
    Clinical and Surgical Sciences Surgery, School of Clinical Sciences and Community Health, The University of Edinburgh, Royal Infirmary, 51 Little France Crescent, Edinburgh EH16 4SA, UK
    Clin Nutr 24:466-77. 2005
  5. ncbi Consensus review of optimal perioperative care in colorectal surgery: Enhanced Recovery After Surgery (ERAS) Group recommendations
    Kristoffer Lassen
    Department of Gastrointestinal Surgery, University Hospital Northern Norway, 9038 Tromsø, Norway
    Arch Surg 144:961-9. 2009
  6. ncbi Herbal medicines and perioperative care
    M K Ang-Lee
    Department of Anesthesia and Critical Care, University of Chicago, 5841 S Maryland Ave, MC 4028, Chicago, IL 60637, USA
    JAMA 286:208-16. 2001
  7. ncbi A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients
    James Dean Sandham
    Faculty of Medicine, University of Calgary, Calgary, Alta, Canada
    N Engl J Med 348:5-14. 2003
  8. ncbi ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise
    Lee A Fleisher
    Circulation 116:1971-96. 2007
  9. ncbi Usefulness of enhanced recovery after surgery protocol as compared with conventional perioperative care in gastric surgery
    Takanobu Yamada
    Department of Gastrointestinal Surgery, Kanagawa Cancer Center, 1 1 2 Nakao, Asahi ku, Yokohama, Kanagawa, Japan
    Gastric Cancer 15:34-41. 2012
  10. ncbi Anaesthesia and myocardial ischaemia/reperfusion injury
    J Frässdorf
    Departement of Anesthesiology, AMC University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands
    Br J Anaesth 103:89-98. 2009

Detail Information

Publications279 found, 100 shown here

  1. ncbi ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guideline
    Lee A Fleisher
    Society for Vascular Medicine and Biology
    Circulation 116:e418-99. 2007
  2. ncbi Laparoscopy in combination with fast track multimodal management is the best perioperative strategy in patients undergoing colonic surgery: a randomized clinical trial (LAFA-study)
    Malaika S Vlug
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    Ann Surg 254:868-75. 2011
    ..To investigate which perioperative treatment, ie, laparoscopic or open surgery combined with fast track (FT) or standard care, is the optimal approach for patients undergoing segmental resection for colon cancer...
  3. ncbi Predictors of length of stay and patient satisfaction after hip and knee replacement surgery: fast-track experience in 712 patients
    Henrik Husted
    Department of Orthopaedics, Copenhagen University Hospital of Hvidovre, Denmark
    Acta Orthop 79:168-73. 2008
    ..The aim of this prospective study was to identify patient characteristics associated with LOS and patient satisfaction after total hip and knee replacement surgery...
  4. ncbi Enhanced recovery after surgery: a consensus review of clinical care for patients undergoing colonic resection
    K C H Fearon
    Clinical and Surgical Sciences Surgery, School of Clinical Sciences and Community Health, The University of Edinburgh, Royal Infirmary, 51 Little France Crescent, Edinburgh EH16 4SA, UK
    Clin Nutr 24:466-77. 2005
    ..There is a need to develop a consensus on key elements of perioperative care for inclusion in enhanced recovery programmes so that these can be widely adopted and refined further in ..
  5. ncbi Consensus review of optimal perioperative care in colorectal surgery: Enhanced Recovery After Surgery (ERAS) Group recommendations
    Kristoffer Lassen
    Department of Gastrointestinal Surgery, University Hospital Northern Norway, 9038 Tromsø, Norway
    Arch Surg 144:961-9. 2009
    To describe a consensus review of optimal perioperative care in colorectal surgery and to provide consensus recommendations for each item of an evidence-based protocol for optimal perioperative care.
  6. ncbi Herbal medicines and perioperative care
    M K Ang-Lee
    Department of Anesthesia and Critical Care, University of Chicago, 5841 S Maryland Ave, MC 4028, Chicago, IL 60637, USA
    JAMA 286:208-16. 2001
    ..Widespread use of herbal medications among the presurgical population may have a negative impact on perioperative patient care...
  7. ncbi A randomized, controlled trial of the use of pulmonary-artery catheters in high-risk surgical patients
    James Dean Sandham
    Faculty of Medicine, University of Calgary, Calgary, Alta, Canada
    N Engl J Med 348:5-14. 2003
    ..Some observational studies suggest that the use of pulmonary-artery catheters to guide therapy is associated with increased mortality...
  8. ncbi ACC/AHA 2007 Guidelines on Perioperative Cardiovascular Evaluation and Care for Noncardiac Surgery: Executive Summary: A Report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise
    Lee A Fleisher
    Circulation 116:1971-96. 2007
  9. ncbi Usefulness of enhanced recovery after surgery protocol as compared with conventional perioperative care in gastric surgery
    Takanobu Yamada
    Department of Gastrointestinal Surgery, Kanagawa Cancer Center, 1 1 2 Nakao, Asahi ku, Yokohama, Kanagawa, Japan
    Gastric Cancer 15:34-41. 2012
    ..The aim of this study was to assess the usefulness of an ERAS protocol for gastric surgery...
  10. ncbi Anaesthesia and myocardial ischaemia/reperfusion injury
    J Frässdorf
    Departement of Anesthesiology, AMC University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands
    Br J Anaesth 103:89-98. 2009
    ..This review will focus on the translation of the laboratory evidence of anaesthetic-induced cardioprotection into daily clinical practice...
  11. ncbi Effect of anaesthetic technique and other perioperative factors on cancer recurrence
    G L Snyder
    Department of Anesthesia and Perioperative Medicine, University of California San Francisco, 505 Parnassus Ave, San Francisco, CA 94143, USA
    Br J Anaesth 105:106-15. 2010
    ..Blood transfusion, pain, stress, and hypothermia are other potentially important perioperative factors to consider...
  12. ncbi Guidelines for perioperative care in elective colonic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations
    U O Gustafsson
    Department of Surgery, Ersta Hospital, Stockholm, Sweden
    Clin Nutr 31:783-800. 2012
    This review aims to present a consensus for optimal perioperative care in colonic surgery and to provide graded recommendations for items for an evidenced-based enhanced perioperative protocol.
  13. ncbi The enhanced recovery after surgery (ERAS) pathway for patients undergoing major elective open colorectal surgery: a meta-analysis of randomized controlled trials
    Krishna K Varadhan
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2 UH, UK
    Clin Nutr 29:434-40. 2010
    ..The objective of this meta-analysis was to study the differences in outcomes in patients undergoing major elective open colorectal surgery within an ERAS pathway and those treated with conventional perioperative care.
  14. ncbi Perioperative immunonutrition for gastrointestinal cancer: a systematic review of randomized controlled trials
    Yan Zhang
    Gansu Provincial Hospital, Donggang West Road No 204, Chengguan District, Lanzhou City, Gansu Province, China
    Surg Oncol 21:e87-95. 2012
    ..To improve the clinical outcome, immunonutrition (IN) was usually used in the patients undergoing elective gastrointestinal caner surgery. However, its effectiveness remains uncertain...
  15. ncbi Guidelines for perioperative care in elective rectal/pelvic surgery: Enhanced Recovery After Surgery (ERAS®) Society recommendations
    J Nygren
    Department of Surgery, Ersta Hospital, Karolinska Institutet, Stockholm, Sweden
    Clin Nutr 31:801-16. 2012
    This review aims to present a consensus for optimal perioperative care in rectal/pelvic surgery, and to provide graded recommendations for items for an evidenced-based enhanced recovery protocol.
  16. ncbi Impact of preoperative nutritional support on clinical outcome in abdominal surgical patients at nutritional risk
    Bin Jie
    Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, China
    Nutrition 28:1022-7. 2012
    ..This multicenter, prospective cohort study evaluated the effect of preoperative nutritional support in abdominal surgical patients at nutritional risk as defined by the Nutritional Risk Screening Tool 2002 (NRS-2002)...
  17. pmc Adherence to perioperative antibiotic prophylaxis among orthopedic trauma patients
    Kristopher M Lundine
    Division of Orthopaedics, Health Sciences Centre, 3330 Hospital Dr NW, Calgary, Alberta
    Can J Surg 53:367-72. 2010
    ..We also investigated what doses and durations of antibiotics are typically ordered, which patients actually receive antibiotics and factors causing the ordered antibiotic regimen to be altered...
  18. ncbi Randomized clinical trial of multimodal optimization and standard perioperative surgical care
    A D G Anderson
    Combined Gastroenterology Unit, Scarborough Hospital, Woodlands Drive, Scarborough YO12 6QL, UK
    Br J Surg 90:1497-504. 2003
    ..The aim of this randomized trial was to compare multimodal optimization with standard care in patients undergoing colonic resection...
  19. ncbi Meta-analysis of laparoscopic versus open colorectal surgery within fast-track perioperative care
    Ming Zhe Li
    Department of Gastrointestinal and Pancreatic Surgery, The First Affiliated Hospital, Sun Yat Sen University, Guangzhou, China
    Dis Colon Rectum 55:821-7. 2012
    Both laparoscopic surgery and fast-track perioperative care have demonstrated advantages in patients undergoing elective colorectal resections. It is unclear whether there is an additive effect by combining these 2 procedures.
  20. ncbi Improving patient safety in the operating theatre and perioperative care: obstacles, interventions, and priorities for accelerating progress
    N Sevdalis
    Department of Surgery and Cancer, Imperial College London, London, UK
    Br J Anaesth 109:i3-i16. 2012
    ....
  21. ncbi Perioperative nutritional management in digestive tract surgery
    Ulf O Gustafsson
    Department of Surgery, Ersta Hospital, Stockholm, Sweden
    Curr Opin Clin Nutr Metab Care 14:504-9. 2011
    ..reviews the recent research on perioperative nutrition in digestive tract surgery in the light of modern perioperative care principles, that is, enhanced recovery after surgery (ERAS)...
  22. ncbi Perioperative nutrition in malnourished surgical cancer patients - a prospective, randomized, controlled clinical trial
    Stanislaw Klek
    Stanley Dudrick s Memorial Hospital, General Surgery Unit, 15 Tyniecka Street, 32 050 Skawina, Poland
    Clin Nutr 30:708-13. 2011
    ..The aim of the study was to evaluate the clinical value of the route and type of perioperative nutritional support...
  23. ncbi Surgical stress response and postoperative immune function after laparoscopy or open surgery with fast track or standard perioperative care: a randomized trial
    A A F A Veenhof
    Department of Surgery, VU University Medical Center, Academic Medical Center, Amsterdam, The Netherlands
    Ann Surg 255:216-21. 2012
    To evaluate the effect of laparoscopic or open colectomy with fast track or standard perioperative care on patient's immune status and stress response after surgery.
  24. ncbi Supplemental perioperative oxygen and the risk of surgical wound infection: a randomized controlled trial
    F Javier Belda
    Department of Anesthesiology and Critical Care, Hospital Clinico Universitario, Valencia, Spain
    JAMA 294:2035-42. 2005
    ..Supplemental perioperative oxygen has been variously reported to halve or double the risk of surgical wound infection...
  25. ncbi [Perioperative management of coagulation]
    P Innerhofer
    Universitätsklinik für Anästhesie und Allgemeine Intensivmedizin, Medizinische Universitat Innsbruck, Anichstr 35, 6020 Innsbruck, Austria
    Hamostaseologie 26:S3-14. 2006
    ....
  26. ncbi Fluid therapy for the surgical patient
    Birgitte Brandstrup
    Surgical Department, Slagelse University Hospital, Ingemannsvej 18, DK 4200 Slagelse, Denmark
    Best Pract Res Clin Anaesthesiol 20:265-83. 2006
    ..Based on current evidence, the principles of 'restricted intravenous fluid therapy' are recommended: fluid lost should be replaced and fluid overload should be avoided...
  27. ncbi ESPEN Guidelines on Enteral Nutrition: Surgery including organ transplantation
    A Weimann
    Klinik f Allgemein und Visceralchirurgie, Klinikum St Georg, Leipzig, Germany
    Clin Nutr 25:224-44. 2006
    ..From a metabolic and nutritional point of view, the key aspects of perioperative care include: Enteral nutrition (EN) by means of oral nutritional supplements (ONS) and if necessary tube feeding ..
  28. ncbi Impact of heart failure on patients undergoing major noncardiac surgery
    Bradley G Hammill
    Center for Clinical and Genetic Economics, Duke Clinical Research Institute, Durham, North Carolina, USA
    Anesthesiology 108:559-67. 2008
    ..The authors evaluated short-term outcomes among patients with heart failure, coronary artery disease (CAD), or neither who underwent major noncardiac surgery...
  29. ncbi Clinical benefits after the implementation of a multimodal perioperative protocol in elderly patients
    José Eduardo de Aguilar-Nascimento
    Department of Surgery, Universidade Federal de Mato Grosso UFMT, Cuiaba, MT, Brazil
    Arq Gastroenterol 47:178-83. 2010
    Multimodal protocol of perioperative care may enhance recovery after surgery. Based on evidence these new routines of perioperative care changed conventional prescriptions in surgery.
  30. ncbi 'Liberal' vs. 'restrictive' perioperative fluid therapy--a critical assessment of the evidence
    M Bundgaard-Nielsen
    Section of Surgical Pathophysiology, University of Copenhagen, Copenhagen, Denmark
    Acta Anaesthesiol Scand 53:843-51. 2009
    ..Several studies have assessed the effect of a 'liberal' vs. a 'restrictive' perioperative fluid regimen on post-operative outcome. The literature was reviewed in order to provide recommendations regarding perioperative fluid regimens...
  31. ncbi The effects of perioperative beta-blockade: results of the Metoprolol after Vascular Surgery (MaVS) study, a randomized controlled trial
    Homer Yang
    Department of Anesthesiology, University of Ottawa, Ottawa, Canada
    Am Heart J 152:983-90. 2006
    ..We report a trial of the perioperative administration of metoprolol and its effects on the incidence of cardiac complications at 30 days and 6 months after vascular surgery...
  32. ncbi Analysis of prognostic factors in seventy patients having a complete cytoreduction plus perioperative intraperitoneal chemotherapy for carcinomatosis from colorectal cancer
    Rodrigo Gomes da Silva
    Washington Cancer Institute, Washington Hospital Center, Washington, DC 20010, USA
    J Am Coll Surg 203:878-86. 2006
    ..Proper selection factors are important because palliative surgery in these patients has not proved beneficial...
  33. doi Fast-track colorectal surgery
    Henrik Kehlet
    Section for Surgical Pathophysiology 4074, Copenhagen University Hospital, Rigshospitalet, 2100 Copenhagen, Denmark
    Lancet 371:791-3. 2008
  34. ncbi Application of perioperative immunonutrition for gastrointestinal surgery: a meta-analysis of randomized controlled trials
    Yamin Zheng
    Department of General Surgery, Xuanwu Hospital, Capital Medical University, No 45 Changchun Street, Beijing 100053, China
    Asia Pac J Clin Nutr 16:253-7. 2007
    ..Further prospective study is required in children or critical patients with gastrointestinal surgery...
  35. ncbi Care after colonic operation--is it evidence-based? Results from a multinational survey in Europe and the United States
    Henrik Kehlet
    Section for Surgical Pathophysiology, Rigshospitalet, Copenhagen, Denmark
    J Am Coll Surg 202:45-54. 2006
    ..This survey investigated clinical practice around colonic operations across Europe and the United States...
  36. ncbi Utility of B-type natriuretic peptide in predicting postoperative complications and outcomes in patients undergoing heart surgery
    Ryan Hutfless
    University of California, San Diego, San Diego, California, USA
    J Am Coll Cardiol 43:1873-9. 2004
    ..The purpose of the present study was to assess whether preoperative and postoperative B-type natriuretic peptide (BNP) levels could be used as predictors of postoperative complications and outcomes in patients after open-heart surgery...
  37. ncbi Perioperative anticoagulation management in patients who are receiving oral anticoagulant therapy: a practical guide for clinicians
    James D Douketis
    Department of Medicine, McMaster University, Hamilton, Ontario, Canada
    Thromb Res 108:3-13. 2002
    ..The objectives of this review are to focus on practical issues relating to perioperative anticoagulation and the implementation of a perioperative anticoagulation management approach that can be used in everyday clinical practice...
  38. ncbi Liberal or restrictive fluid administration in fast-track colonic surgery: a randomized, double-blind study
    K Holte
    Department of Surgical Gastroenterology, Hvidovre University Hospital, DK 2650 Hvidovre, Denmark
    Br J Anaesth 99:500-8. 2007
    ..Therefore, we investigated the effects of two regimens of intraoperative fluids with physiological recovery as the primary outcome measure after fast-track colonic surgery...
  39. ncbi Postoperative complications in gastrointestinal cancer patients: the joint role of the nutritional status and the nutritional support
    Federico Bozzetti
    Department of Surgery, Hospital of Prato, Piazza dell Ospedale 5, 59100 Prato, Italy
    Clin Nutr 26:698-709. 2007
    ..This study investigated the effects of nutritional support on postoperative complications, in relation with demographic and nutritional factors, intraoperative factors, type and routes of nutritional regimens...
  40. ncbi Systematic review of enhanced recovery programmes in colonic surgery
    J Wind
    Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands
    Br J Surg 93:800-9. 2006
    Fast track (FT) programmes optimize perioperative care in an attempt to accelerate recovery, reduce morbidity and shorten hospital stay. The aim of this review was to assess FT programmes for elective segmental colonic resections.
  41. ncbi Coronary artery stenting and non-cardiac surgery--a prospective outcome study
    M N Vicenzi
    Department of Anaesthesiology and Intensive Care Medicine, Medical University of Graz, Austria
    Br J Anaesth 96:686-93. 2006
    ..Therefore we undertook a prospective, observational multicentre study with predefined heparin therapy and antiplatelet medication in patients undergoing non-cardiac procedures after coronary artery stenting...
  42. pmc Improvement in perioperative outcome after hepatic resection: analysis of 1,803 consecutive cases over the past decade
    William R Jarnagin
    Departments of Surgery and Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    Ann Surg 236:397-406; discussion 406-7. 2002
    ..To assess the nature of changes in the field of hepatic resectional surgery and their impact on perioperative outcome...
  43. ncbi Impact of fresh frozen plasma on hepatectomy for hepatocellular carcinoma
    Masaki Kaibori
    Department of Surgery, Hirakata Hospital, Kansai Medical University, Hirakata, Osaka 573 1191, Japan
    Anticancer Res 28:1749-55. 2008
    ..Little is known about the effect of transfusing fresh frozen plasma on the outcome after hepatectomy for hepatocellular carcinoma...
  44. ncbi Urgent surgery in patients with a recently implanted coronary drug-eluting stent: a phase II study of 'bridging' antiplatelet therapy with tirofiban during temporary withdrawal of clopidogrel
    S Savonitto
    Department of Cardiology, Ospedale Niguarda Ca Granda, Piazza Ospedale Maggiore 3, 20162 Milan, Italy
    Br J Anaesth 104:285-91. 2010
    ..This pilot study tested the hypothesis that the i.v. perioperative administration of the short-acting antiplatelet agent tirofiban allows the safe withdrawal of clopidogrel without increasing the rate of surgical bleeding...
  45. ncbi Anesthesia-related cardiac arrest in children: update from the Pediatric Perioperative Cardiac Arrest Registry
    Sanjay M Bhananker
    Department of Anesthesiology, University of Washington School of Medicine, Seattle, WA, USA
    Anesth Analg 105:344-50. 2007
    ..Changes in pediatric anesthesia practice may have altered the causes of cardiac arrest in anesthetized children...
  46. ncbi Cost-effectiveness of accelerated perioperative care and rehabilitation after total hip and knee arthroplasty
    Kristian Larsen
    Orthopedic Research Unit, Orthopedic Department, Regional Hospital Holstebro, Laegaardvej, 7500 Holstebro, Denmark
    J Bone Joint Surg Am 91:761-72. 2009
    ..We compared the cost-effectiveness of an accelerated perioperative care and rehabilitation protocol with that of a more standard protocol for patients treated with total hip and ..
  47. ncbi The role of the anesthesiologist in fast-track surgery: from multimodal analgesia to perioperative medical care
    Paul F White
    Department of Anesthesiology and Pain Management, University of Texas Southwestern Medical Center at Dallas, Texas, USA
    Anesth Analg 104:1380-96, table of contents. 2007
    ..e., outpatient) and major (inpatient) surgery procedures. In this article we focus on the expanding role of the anesthesiologist in fast-track surgery...
  48. ncbi The pharmaco-economics of peri-operative statin therapy
    B M Biccard
    Nuffield Department of Anaesthetics, University of Oxford, John Radcliffe Hospital, Headley Way, Headington, Oxford, OX3 9DU, UK
    Anaesthesia 60:1059-63. 2005
    ....
  49. ncbi Optimizing perioperative care in bariatric surgery patients
    Daniel P Lemanu
    Department of Surgery, South Auckland Clinical School, Middlemore Hospital, University of Auckland, Private Bag 93311, Otahuhu, Auckland, New Zealand
    Obes Surg 22:979-90. 2012
    ..gastric bypass', 'ERAS', 'enhanced recovery', 'enhanced recovery after surgery', 'fast-track surgery', 'perioperative care', 'postoperative care', 'intraoperative care' and 'preoperative care'...
  50. ncbi Thoracic epidural analgesia facilitates the restoration of bowel function and dietary intake in patients undergoing laparoscopic colon resection using a traditional, nonaccelerated, perioperative care program
    A Taqi
    Department of Surgery, McGill University Health Centre, 1650, Cedar Avenue, Room D10 144, Montreal, H3G 1A4, Quebec, Canada
    Surg Endosc 21:247-52. 2007
    This randomized trial compared thoracic epidural analgesia with patient-controlled analgesia (PCA) using morphine for laparoscopic colectomy in a traditional, nonaccelerated, perioperative care program.
  51. pmc Effect of perioperative autologous versus allogeneic blood transfusion on the immune system in gastric cancer patients
    Gang Chen
    Department of Anesthesiology, The Second Affiliated Hospital, School of Medicine, Zhejiang University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 8:560-5. 2007
    ..The purpose was to further evaluate the effect of autologous versus allogeneic blood transfusion on immunological status in patients undergoing surgery for gastric cancer...
  52. ncbi Management of perioperative nutrition support
    Robert G Martindale
    Oregon Health and Science University, Portland, Oregon 97239, USA
    Curr Opin Crit Care 12:290-4. 2006
    ..Issues specifically addressed include which patients are most likely to benefit from perioperative nutritional supplementation, and the optimal route, timing, and quantity of nutrient delivery...
  53. ncbi Perioperative care for the elderly patient
    Margaret M Beliveau
    Division of General Internal Medicine, Mayo Clinic, 200 First Street, South West, Rochester, MN 55905, USA
    Med Clin North Am 87:273-89. 2003
    ..Using this information, patients can be clinically evaluated effectively and plans made for their perioperative care to minimize complications.
  54. ncbi The influence of perioperative care and treatment on the 4-month outcome in elderly patients with hip fracture
    Karin B Bjorkelund
    Lund University, Department of Health Sciences, Lund, Sweden
    AANA J 79:51-61. 2011
    ..To minimize morbidity and mortality, providers should increase efforts to optimize the patients' oxygen saturation and hemoglobin level and reduce fasting time and waiting time for surgery...
  55. ncbi Perioperative care of patients with epidermolysis bullosa: proceedings of the 5th international symposium on epidermolysis bullosa, Santiago Chile, December 4-6, 2008
    Kenneth Goldschneider
    Division of Pain Management, Department of Anesthesiology, Cincinnati Children s Hospital Medical Center, Cincinnati, OH, USA
    Paediatr Anaesth 20:797-804. 2010
    ..interdisciplinary panel of experts assembled in Santiagio, Chile to review the best practices for perioperative care of patients with EB...
  56. ncbi Perioperative antibiotic prophylaxis: improved compliance and impact on infection rates
    E Prospero
    Department of Biomedical Sciences, Section of Hygiene, Public Health and Preventive Medicine, Universita Politecnica delle Marche, Ancona, Italy
    Epidemiol Infect 139:1326-31. 2011
    ....
  57. ncbi Point-of-care assessment of antiplatelet agents in the perioperative period: a review
    N M Gibbs
    Department of Anaesthesia, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Anaesth Intensive Care 37:354-69. 2009
    ..The strengths and limitations of point-of-care devices should be appreciated before they are used to assist clinical decision-making in the perioperative period...
  58. ncbi Enhanced recovery after surgery versus conventional perioperative care in rectal surgery
    Pascal H E Teeuwen
    Department of Surgery, Division of Gastro intestinal Surgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    Dis Colon Rectum 54:833-9. 2011
    ..Enhanced recovery after surgery programs have been developed to improve recovery, shorten hospital stays, and reduce morbidity...
  59. ncbi Outcomes in perioperative care
    Jean Mantz
    Department of Anesthesiology and Critical Care, Beaujon University Hospital, Paris 7 Paris Diderot University, Clichy, France
    Curr Opin Anaesthesiol 23:201-8. 2010
    The present review examines the trends and controversies on how perioperative care can influence outcome after anesthesia and surgery.
  60. ncbi Does perioperative systolic blood pressure variability predict mortality after cardiac surgery? An exploratory analysis of the ECLIPSE trials
    Solomon Aronson
    Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
    Anesth Analg 113:19-30. 2011
    ..We tested the hypothesis that systolic blood pressure (SBP) variability in patients undergoing cardiac surgery is associated with 30-day mortality...
  61. ncbi Perioperative care of the child with arthrogryposis
    Sam Martin
    Department of Anesthesiology, University of Missouri, Columbia, MO 65212, USA
    Paediatr Anaesth 16:31-7. 2006
    ..AMC results from fetal akinesia due to extrinsic factors (oligohydramnios) or primary neurogenic or myopathic conditions of the fetus...
  62. ncbi Pharmacologic properties of the new oral anticoagulants: a clinician-oriented review with a focus on perioperative management
    James D Douketis
    Department of Medicine, McMaster University, St Joseph s Healthcare, 50 Charlton Avenue East, Hamilton, Ontario, Canada
    Curr Pharm Des 16:3436-41. 2010
    ....
  63. ncbi Quality assessment of clinical practice guidelines in perioperative care: a systematic appraisal
    Leticia Barajas-Nava
    Iberoamerican Cochrane Centre, Clinical Epidemiology and Public Health Department, Hospital de la Santa Creu i Sant Pau, Sant Antoni M Claret 171, 08041 Barcelona, Spain
    Qual Saf Health Care 19:e50. 2010
    ..Clinical practice guidelines in perioperative care should provide the opportunity to minimise these risks and improve surgical outcomes, but their quality has ..
  64. pmc Variation in perioperative care across centers for infants undergoing the Norwood procedure
    Sara K Pasquali
    Department of Pediatrics and Duke Clinical Research Institute, Duke University Medical Center, Durham, NC, USA
    J Thorac Cardiovasc Surg 144:915-21. 2012
    ..Apart from shunt type, subjects received the local standard of care. We evaluated variation in perioperative care during the Norwood hospitalization across 14 trial sites.
  65. ncbi Perioperative hyperinsulinaemic normoglycaemic clamp causes hypolipidaemia after coronary artery surgery
    C J Zuurbier
    Department of Anaesthesiology, Academic Medical Center, University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    Br J Anaesth 100:442-50. 2008
    ..The present study examines lipids and other substrates during and after on-pump coronary artery bypass grafting and how they are affected by a hyperinsulinaemic normoglycaemic clamp...
  66. ncbi The implementation of a perioperative checklist increases patients' perioperative safety and staff satisfaction
    A B Böhmer
    Department of Anaesthesiology, Hospital Cologne Merheim, University Hospital of the Witten Herdecke University, Cologne, Germany
    Acta Anaesthesiol Scand 56:332-8. 2012
    ..The aim of the present study was to evaluate perioperative safety standards and the quality of interprofessional cooperation before and after the introduction of a safety checklist from staff members' point of view...
  67. pmc Management plan to reduce risks in perioperative care of patients with presumed obstructive sleep apnea syndrome
    Bhargavi Gali
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    J Clin Sleep Med 3:582-8. 2007
    ..We initiated a protocol designed to screen patients preoperatively and monitor them postoperatively. The goal was to identify patients who were at risk for oxygen desaturation after discharge from the postanesthesia recovery room (PACU)...
  68. ncbi Perioperative care of a patient with Beare-Stevenson syndrome
    Sara Upmeyer
    Department of Anesthesiology, University of Missouri, Columbia, MO 65212, USA
    Paediatr Anaesth 15:1131-6. 2005
    ..The authors present their experience caring for a patient with Beare-Stevenson syndrome and discuss the anesthesia care of these patients...
  69. ncbi Perioperative parenteral nutrition: impact on morbidity and mortality in surgical patients
    Charlene W Compher
    Penn Nursing and Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Nutr Clin Pract 20:460-7. 2005
  70. ncbi Goal-directed haemodynamic therapy and gastrointestinal complications in major surgery: a meta-analysis of randomized controlled trials
    M T Giglio
    Anaesthesia and Intensive Care Unit, Department of Emergency and Organ Transplantation, University of Bari, Policlinico, Piazza G Cesare 11, 70124 Bari, Italy
    Br J Anaesth 103:637-46. 2009
    ..In patients undergoing major surgery, GDT, by maintaining an adequate systemic oxygenation, can protect organs particularly at risk of perioperative hypoperfusion and is effective in reducing GI complications...
  71. ncbi Perioperative tight glucose control with hyperinsulinemic-normoglycemic clamp technique in cardiac surgery
    Hiroaki Sato
    Department of Anaesthesia, Royal Victoria Hospital, McGill University Health Center, Montreal, Quebec, Canada
    Nutrition 26:1122-9. 2010
    ..The purpose of this study was to evaluate the efficacy of perioperative glucose and insulin administration while maintaining normoglycemia using a hyperinsulinemic-normoglycemic clamp technique...
  72. ncbi Perioperative care of the elderly patient: an update
    Robert M Palmer
    Division of Geriatric Medicine, University of Pittsburgh, Kaufmann Medical Building, Pittsburgh, PA 15213, USA
    Cleve Clin J Med 76:S16-21. 2009
    ..General recommendations for the perioperative care of elderly patients include avoiding drugs that raise the risk of delirium, ensuring adequate caloric and ..
  73. ncbi Peri-operative nutritional management
    Federico Bozzetti
    Faculty of Medicine, University of Milan, Milan, Italy
    Proc Nutr Soc 70:305-10. 2011
    ..This paper will focus on the updated evidence-based research on peri-operative nutrition (parenteral, enteral and immune-enhancing) in patients undergoing major surgery...
  74. ncbi Perioperative management of morbid obesity
    Sammy Al-Benna
    St Bartholomew s Hospital, West Smithfield, London, ECIA 7BE
    J Perioper Pract 21:225-33. 2011
    ..Given these proportions, and that an increasing number of morbidly obese patients are undergoing weight loss surgery and procedures related to obesity, it is an opportune time to review the perioperative care of morbidly obese patients.
  75. ncbi Optimizing cost-effectiveness in perioperative care for liver transplantation: a model for low- to medium-income countries
    Karina Rando
    Department of Hepatic Diseases, Military Hospital, Montevideo, Uruguay
    Liver Transpl 17:1247-78. 2011
    ..Cost-effectiveness data for LT are limited, especially in perioperative care, and the techniques and costs vary widely between centers without overt differences in outcomes...
  76. ncbi Perioperative monitoring of thromboelastograph on blood protection and recovery for severely cyanotic patients undergoing complex cardiac surgery
    Yongli Cui
    Department of Cardiopulmonary Bypass, Cardiovascular Institute and Fuwai Hospital, CAMS, and PUMS, Beijing, China
    Artif Organs 34:955-60. 2010
    ..05). So, TEG was effective in perioperative blood protection. Fibrinogen could be a substitute for FFP to restore hemostasis and improve the prognosis for these patients...
  77. ncbi Effect of adjuvant perioperative desmopressin in locally advanced canine mammary carcinoma and its relation to histologic grade
    Guillermo A Hermo
    Laboratory of Molecular Oncology, Department of Science and Technology, Quilmes National University, Buenos Aires, Argentina
    J Am Anim Hosp Assoc 47:21-7. 2011
    ..The present data suggest that DDAVP may be an excellent candidate as a surgical adjuvant in the management of aggressive cancers in small animals. More research in this field is warranted...
  78. ncbi Living donor liver transplantation: selection, perioperative care, and outcome
    Bhargavi Gali
    Department of Anesthesiology, Mayo Clinic, Rochester, MN 55905, USA
    J Intensive Care Med 27:71-8. 2012
    ..Close immediate postoperative monitoring and meticulous management will remain an essential aspect in limiting donor complications and deaths...
  79. ncbi Multimodal multidisciplinary standardization of perioperative care: still a long way to go
    Jan Klein
    Department of Anesthesiology, Erasmus University Medical Center Rotterdam, The Netherlands
    Curr Opin Anaesthesiol 21:187-90. 2008
    The complexity of the perioperative care process has resulted in a suboptimal use of resources, quality problems and a relatively high incidence of errors...
  80. ncbi Patient's satisfaction with perioperative care: development, validation, and application of a questionnaire
    M A A Caljouw
    Operating Theatre Centre, Leiden University Medical Centre, Postal Zone J4 Q, PO Box 9600, 2300 RC Leiden, The Netherlands
    Br J Anaesth 100:637-44. 2008
    ..The aim of our study was to develop a valid and reliable self-reported multidimensional questionnaire assessing patient satisfaction that included these issues...
  81. ncbi Perioperative antibiotic prophylaxis in the gastric bypass patient: do we achieve therapeutic levels?
    Charles E Edmiston
    Department of Surgery, Medical College of Winsconsin, Milwaukee, 53226, USA
    Surgery 136:738-47. 2004
    ..Perioperative surgical antibiotic prophylaxis requires that therapeutically effective drug concentrations be present in the tissues...
  82. ncbi [Perioperative management of patients with coronary stents in non-cardiac surgery]
    C Jambor
    Arbeitsgruppe Perioperative Hämostase, Klinik fur Anaesthesiologie, Ludwig Maximilians Universitat Munchen, Max Lebsche Platz 32, 81377, Munchen
    Anaesthesist 58:971-85. 2009
    ..Whether bedside monitoring of antiplatelet therapy improves the perioperative management of these patients and reduces adverse outcome is object of current studies...
  83. ncbi Perioperative handling of patients on antiplatelet therapy with need for surgery
    Matteo Nicola Dario Di Minno
    Department of Experimental and Clinical Medicine, Federico II University, Via Sergio Pansini 5, 80131 Naples, Italy
    Intern Emerg Med 4:279-88. 2009
    ..Aprotinin decreases postoperative bleeding and transfusion rates in patients undergoing CABG and on clopidogrel during the days preceding surgery...
  84. ncbi Antiplatelet agents in the perioperative period
    James M O'Riordan
    Department of Surgery, Mater Misericordiae University Hospital, Dublin, Ireland
    Arch Surg 144:69-76; discussion 76. 2009
    ..To determine the use of the 3 major classes of antiplatelet drugs (aspirin, thienopyridines, and glycoprotein IIb/IIIa inhibitors), their management in the perioperative period, and the risks associated with premature withdrawal...
  85. ncbi Update in perioperative medicine
    Gerald W Smetana
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts 02215, USA
    Ann Intern Med 140:452-61. 2004
  86. ncbi Accelerated perioperative care and rehabilitation intervention for hip and knee replacement is effective: a randomized clinical trial involving 87 patients with 3 months of follow-up
    Kristian Larsen
    The Musculoskeletal Research Unit, Department of Orthopedics, Holstebro Regional Hospital, Holstebro, Denmark
    Acta Orthop 79:149-59. 2008
    ..We therefore performed an efficacy study of an accelerated perioperative care and rehabilitation intervention in patients receiving primary total hip replacement, and both total and ..
  87. ncbi [Perioperative therapy with antiplatelet agents]
    W Lepper
    Medizinische Klinik I, Kardiologie, Pulmonologie und Angiologie, Universitätsklinikum der RWTH Aachen, Pauwelsstrasse 30, 52057 Aachen
    Anaesthesist 56:592-8. 2007
    ..Especially patients with intracoronary stents are at threat when the dual platelet therapy is interrupted before complete endothelialization of the stent...
  88. ncbi Cardiac screening before noncardiac surgery
    Freddie M Williams
    Cardiovascular Medicine, University of Virginia Health System, 1215 Lee Street, Box 800158, Charlottesville, VA 22908, USA
    Surg Clin North Am 89:747-62, vii. 2009
    ..beta-Blocker therapy has become controversial in light of recent publications but should be continued in patients already on therapy, and started in patients with high cardiac risk undergoing intermediate- or high-risk surgery...
  89. ncbi The effects of fasting and refeeding with a 'metabolic preconditioning' drink on substrate reserves and mononuclear cell mitochondrial function
    Sherif Awad
    Division of Gastrointestinal Surgery, Nottingham Digestive Diseases Centre NIHR Biomedical Research Unit, Nottingham University Hospitals, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Clin Nutr 29:538-44. 2010
    ....
  90. ncbi Preventing surgical site infections
    Ilker Uckay
    Infection Control Programme, University of Geneva Hospitals and Faculty of Medicine, 4 rue Gabrielle Perret Gentil, 1211 Geneva 14, Switzerland
    Expert Rev Anti Infect Ther 8:657-70. 2010
    ..Although theoretically reducible to zero, the maximal realistic extent by which SSI can be decreased remains unknown...
  91. ncbi Point of controversy: perioperative care of patients undergoing pheochromocytoma removal-time for a reappraisal?
    Claude Lentschener
    Departments of Anesthesia and Critical Care Digestive and Endocrine Surgery, Faculte de Medecine, Assistance Publique Hopitaux de Paris, Hopital Cochin, EA 3623, Universite Paris Descartes, 27 rue du Faubourg Saint Jacques, 75679 Paris Cedex 14, France
    Eur J Endocrinol 165:365-73. 2011
    ..We reviewed available literature in this respect...
  92. ncbi beta-Blockers and reduction of cardiac events in noncardiac surgery: clinical applications
    Andrew D Auerbach
    Department of Medicine, Box 0120, University of California, San Francisco, San Francisco, CA 94143 0120, USA
    JAMA 287:1445-7. 2002
    ..Even though fine points of their use remain to be elucidated, perioperative beta-blocker use is important and can be easily applied in practice by any physician involved with the care of patients perioperatively...
  93. ncbi Maintenance of normoglycemia during cardiac surgery
    George Carvalho
    Department of Anesthesia, McGill University, Royal Victoria Hospital, Room S5 05, 687 Pine Avenue West, Montreal, Quebec, Canada H3A 1A1
    Anesth Analg 99:319-24, table of contents. 2004
    ..In conclusion, it seems that normal blood glucose concentration during open heart surgery can be reliably maintained in nondiabetic and diabetic patients by using the hyperinsulinemic normoglycemic clamp technique...
  94. ncbi A combination of statins and beta-blockers is independently associated with a reduction in the incidence of perioperative mortality and nonfatal myocardial infarction in patients undergoing abdominal aortic aneurysm surgery
    M D Kertai
    Department of Cardiology, Erasmus MC, Rotterdam, The Netherlands
    Eur J Vasc Endovasc Surg 28:343-52. 2004
    ..To investigate the combined beneficial effect of statin and beta-blocker use on perioperative mortality and myocardial infarction (MI) in patients undergoing abdominal aortic aneurysm surgery (AAA)...
  95. pmc Effects of intravenous fluid restriction on postoperative complications: comparison of two perioperative fluid regimens: a randomized assessor-blinded multicenter trial
    Birgitte Brandstrup
    Clinical Unit of Preventive Medicine and Health Promotion, H S Bispebjerg University Hospital, Bispebjerg Bakke 23, DK 2400 Copenhagen NV, Denmark
    Ann Surg 238:641-8. 2003
    ..To investigate the effect of a restricted intravenous fluid regimen versus a standard regimen on complications after colorectal resection...
  96. ncbi Perioperative blood transfusion in hepatocellular carcinomas: influence of immunologic profile and recurrence free survival
    A H Kwon
    First Department of Surgery, Kansai Medical University, 10 15 Fumizono, Moriguchi, Osaka, 570 8507, Japan
    Cancer 91:771-8. 2001
    ..The authors prospectively investigated the relation between perioperative allogeneic blood transfusions, the recurrence free survival, and the immunologic profiles of patients with HCC who had undergone curative hepatic resections...
  97. ncbi Perioperative nutrition support: who and how
    Richard M Salvino
    Department of Gastroenterology, MetroHealth Medical Center, Cleveland, OH, USA
    Cleve Clin J Med 71:345-51. 2004
    ....
  98. ncbi Coagulation monitoring: current techniques and clinical use of viscoelastic point-of-care coagulation devices
    Michael T Ganter
    Department of Anesthesia and Perioperative Care, University of CA San Francisco, San Francisco, California, USA
    Anesth Analg 106:1366-75. 2008
    ..To ensure optimal accuracy and performance, standardized procedures for blood sampling and handling, strict quality controls and trained personnel are required...
  99. ncbi [Perioperative care in digestive surgery]
    C Mariette
    Service de Chirurgie Digestive et Generale, Hopital C Huriez, CHRU, Lille
    J Chir (Paris) 142:14-28. 2005
  100. ncbi Perioperative beta-blocker therapy and mortality after major noncardiac surgery
    Peter K Lindenauer
    Division of Healthcare Quality, Baystate Medical Center, Springfield, Mass 01199, USA
    N Engl J Med 353:349-61. 2005
    ..We assessed the use of perioperative beta-blockers and their association with in-hospital mortality in routine clinical practice...
  101. ncbi Perioperative beta-blockade (POBBLE) for patients undergoing infrarenal vascular surgery: results of a randomized double-blind controlled trial
    A R Brady
    Department of Vascular Surgery, Imperial College, Charing Cross Campus, London, UK
    J Vasc Surg 41:602-9. 2005
    ....

Research Grants52

  1. Integrating Perioperative Care into the Treatment of Hypertension
    ROBERT SCHONBERGER; Fiscal Year: 2013
    ....
  2. Surgical Treatment Outcomes for Patients with Psychiatric Disorders (STOPP)
    Laurel A Copeland; Fiscal Year: 2013
    ..The proposed work will lay the groundwork for identifying and developing interventions to improve perioperative care of these patients.
  3. Pediatric Heart Network Regents of the University of Michigan
    Richard G Ohye; Fiscal Year: 2013
    ..patient group, has improved markedly in the past 30 years due to innovations and refinements in surgical and perioperative care. The Norwood operation, the first step in the 3-stage surgical palliation for these children is now ..
  4. Obesity and Surgical Outcomes
    Jeffrey H Silber; Fiscal Year: 2010
    ..in the care of obese surgical patients that will have a significant impact on the surgical approach to, and perioperative care of, the elderly obese...
  5. Volatile anesthetic alteration of neural precursor cell cycle and fate decisions
    Jeffrey W Sall; Fiscal Year: 2013
    ..will be carried out at the University of California, San Francisco in the department of Anesthesia and Perioperative Care, one of the top departments in this field...
  6. Dissemination of Patient Centered Outcomes in Anesthesia Care
    Richard P Dutton; Fiscal Year: 2013
    ..The Anesthesia Quality Institute (AQI) was created by ASA to improve perioperative care through development of the National Anesthesia Clinical Outcomes Registry (NACOR)...
  7. Hyperinsulinemic glucose control and myocardial function during cardiac surgery
    Andra E Duncan; Fiscal Year: 2013
    ..development of advanced echocardiographic skills with important research applications for investigating perioperative care of complex cardiac surgical patients;4) an investigation in basic science research to elucidate the cellular ..
  8. Anesthetics and Alzheimer's Disease
    Roderic G Eckenhoff; Fiscal Year: 2012
    ..and the public health and societal challenge of caring for the demented, it is imperative that we design our perioperative care in a way that avoids contributions to neurodegeneration...
  9. Voltage gated sodium channels in acute post laminectomy pain
    CHRISTINA MARIE SPOFFORD; Fiscal Year: 2013
    ..This work will provide much needed information for future development of novel analgesics that are devoid of serious side effects, enabling physicians to provide better perioperative care to surgical patients.
  10. Structure, Process and Outcomes in Cancer Surgery
    John D Birkmeyer; Fiscal Year: 2010
    ..Variation in specific medical complications would instead suggest the need to focus on processes related to perioperative care. In this context, our project has two specific aims: 1...
  11. ANESTHETICS AND CARDIOPROTECTIVE SIGNAL TRANSDUCTION
    Judy Kersten; Fiscal Year: 2001
    ..will provide a foundation for the development of the candidate as an independent investigator, and the results will ultimately contribute to improvement in the perioperative care of patients with cardiovascular disease. (End of abstract)
  12. Improving the Quality and Safety of Regional Surgical P*
    Michael Higgins; Fiscal Year: 2004
    ..region's patients, 2) a preoperative evaluation resource containing the medical history relevant to planning perioperative care, 3) the creation of a perioperative database core to support health services research initiatives, 4) a ..
  13. Elective Surgery as a Teachable Moment for Smoking Cessation
    David Warner; Fiscal Year: 2007
    ..Our overall goal is to develop effective tobacco use interventions for surgical patients; this project will be an important step in this process. [unreadable] [unreadable] [unreadable]..
  14. Improving use of peri-operative beta-blockers with a multidimentional QI program
    Andrew Auerbach; Fiscal Year: 2009
    ..The impact of this set of tools will be substantial as groups such as the NSQIP, SCIP, National Quality Forum, and Leapfrog Group continue to endorse PBB as a key strategy to reduce surgical morbidity and mortality. ..
  15. Endothelial progenitor cells and surgical outcomes
    Andrew Auerbach; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  16. Neurophysiologic Development Responses to Surgery
    DOUGLAS RIRIE; Fiscal Year: 2007
    ..Through this and future studies which come from this data and training, improvement in understanding will hopefully lead to improved pain therapy that is developmentally appropriate. ..
  17. Pharmacotherapy for Minor Depression
    Robert Howland; Fiscal Year: 2004
    ..The results of this study will have profound public health implications by improving our understanding of the efficacy of SJW and standard antidepressants for the treatment of MinorD. ..
  18. Diabetes Management for Low-Income Hispanic Patients
    Milagros Rosal; Fiscal Year: 2007
    ..The study products (i.e., detailed intervention manual, tailored educational materials, manual for training of providers) will serve to enhance the translation potential of the intervention. ..
  19. RANKL and BMPs in Prostate Cancer Induced Bone Lesions
    Jay Lieberman; Fiscal Year: 2007
    ..abstract_text> ..
  20. Markers of normoglycemic remission in obese diabetics
    Guillermo Umpierrez; Fiscal Year: 2006
    ..Identifying such markers will facilitate and guide future therapeutic interventions and may identify patients at risk to develop chronic complications of diabetes ..
  21. NABTC Member Intitution Grant (UCSF Project Leader)
    Susan Chang; Fiscal Year: 2008
    ..The overall goal of this program is to more effectively treat patients with primary brain tumors, especially malignant glioma, with the purpose of increasing the duration and quality of survival. ..
  22. MOLECULAR DISTRIBUTION OF HUMAN ADRENERGIC RECEPTORS
    Debra Schwinn; Fiscal Year: 2003
    ..Results from these studies should facilitate therapeutic interventions (e.g. enhanced human tissue targeting for gene therapy) as well as understanding of mechanisms underlying cardiovascular diseases...
  23. Phase II Clinical Trial Utilizing Lithium for Patients with Neuroendocrine Tumors
    Herbert Chen; Fiscal Year: 2008
    ..Besides surgery, there are limited curative and palliative treatments available to patients with metastatic NE tumors, emphasizing the need for development of other forms of therapy. [unreadable] [unreadable] [unreadable]..
  24. Regulating Neuroendocrine Phenotype in Cancer
    Herbert Chen; Fiscal Year: 2010
    ..Furthermore, these finding may permit development of components of raf-1 pathway as therapeutic targets in the treatment and palliation of NE tumors. ..
  25. Real-time multiphoton microscopy of periprostatic tissue architecture
    Ashutosh K Tewari; Fiscal Year: 2010
    ..The dynamic, high-resolution optical images achieved could empower cancer surgeons to better distinguish tissue morphology during surgery, leading to improved functional outcomes and quality of life for their patients. ..
  26. Apoptosis in myelofibrosis with myeloid metaplasia
    Ruben Mesa; Fiscal Year: 2006
    ..abstract_text> ..
  27. Improving Institutional Animal Resources at MUSC
    MARVIN SWINDLE; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable]..
  28. PHARMACOLOGY OF VASCULAR AL-ADRENERGIC RECEPTORS
    Debra Schwinn; Fiscal Year: 2004
    ..They propose testing these polymorphisms for functional significance in tissue culture and correlating each polymorphism with vascular. ..
  29. A NEURAL NETWORK APPROACH TO PEDIATRIC TRAUMA TRIAGE
    RANDALL BURD; Fiscal Year: 2004
    ..The classification accuracy of trained networks will be compared with that based on current triage strategies. The long-term goal of this project is to develop and implement a tool for triaging injured children based on neural networks. ..
  30. Signaling Pathways in Medullary Thyroid Cancer
    Herbert Chen; Fiscal Year: 2004
    ..abstract_text> ..
  31. DEVELOPING BSL3 ANIMAL FACILITIES AT MUSC
    MARVIN SWINDLE; Fiscal Year: 2004
    ..The facility will be in full compliance with CDC and NIH regulations for performing this type of research. ..
  32. IMPROVING INSTITUTIONAL ANIMAL RESOURCES
    MARVIN SWINDLE; Fiscal Year: 2003
    ....
  33. Functional decline following surgery in older adults
    VICTOR LEGNER; Fiscal Year: 2004
    ..Identified modifiable factors will direct future interventions in older adults at highest risk for functional decline following surgery. ..
  34. HEART RATE RECOVERY AND MORTALITY
    Michael Lauer; Fiscal Year: 2002
    ..All the data needed for this project are already electronically available; that fact, along with the work already done, lends confidence to the feasibility of this project. ..
  35. Nanostenting Hydrogels for Sinus Surgery
    RICHARD ORLANDI; Fiscal Year: 2004
    ..The results of these Phase I studies will determine the feasibility and the optimal chemical properties of a nanostenting HA gel for human trials. ..
  36. Novel Signaling Targets in GI Neuroendocrine Tumors
    Herbert Chen; Fiscal Year: 2005
    ..The possibility that raf-l-mediated hormone suppression could be induced by a soluble factor would provide a plausible, therapeutic delivery method. ..
  37. Neonatal Pain, Adult Biobehavioral Responses to Stress
    Gayle Page; Fiscal Year: 2005
    ..Findings from these studies will demonstrate possible negative physiologic and behavioral sequelae of repeated painful experiences during neonatal development as well as suggest potential preventive interventions. ..
  38. PERIOPERATIVE PAIN, IMMUNE FUNCTION, AND METASTASIS
    Gayle Page; Fiscal Year: 2001
    ....
  39. The Effect of Sedation on Restorative Sleep
    Avery Tung; Fiscal Year: 2005
    ..Knowledge from this proposal will provide scientific insight into the relationships between anesthesia and sleep, and may lead to more effective clinical use of ICU sedatives. ..
  40. OU Human Research Protection Program, Year 2
    Gary Raskob; Fiscal Year: 2003
    ..The University of Oklahoma is committed to maintaining these initiatives after the term of this award. ..
  41. Advancing Clinical Research in Pediatric Surgery
    KEVIN LALLY; Fiscal Year: 2006
    ..Lally with his research and mentoring to advance the quality of clinical research in pediatric surgery, develop an expanded international trials network, and improve the outcome of high-risk infants. ..
  42. OU Developmental Center for Injury Prevention Research
    Gary Raskob; Fiscal Year: 2005
    ..abstract_text> ..
  43. AMINO ACID TRANSPORT AFTER SMALL BOWEL RESECTION
    HARRY SAX; Fiscal Year: 2004
    ....
  44. T CELL ADHESION MOLECULES IN MURINE LUPUS PNEUMONITIS
    Jeffrey Curtis; Fiscal Year: 2002
    ..Our long-term goal is to develop effective therapies to treat established SLE based on anti-adhesive strategies. ..
  45. B ADRENOCEPTORS DURING CARDIOPULMONARY BYPASS
    Debra Schwinn; Fiscal Year: 2001
    ..It is anticipated that prevention of myocardial betaAR desensitization during cardiac surgery should lead to enhanced myocardial performance at the time of separation from CPB and use of fewer inotropic drugs. ..
  46. Persistent Mechanical Hypersensitivity in Rats: Biobehavioral Effects
    Gayle Page; Fiscal Year: 2009
    ..The relevance of the proposed study to human health is the goal to discern what factors (e.g., sleep disruption, biological responses to stress and anxiety) increase one s risk to develop chronic pain. ..
  47. Pain Assessment in Cognitively Impaired Children
    Shobha Malviya; Fiscal Year: 2005
    ..A reliable and valid pain assessment tool is critical to facilitate our future study of pain management strategies in these children. ..
  48. Vein wall remodeling after DVT is matrix metalloproteinase dependent
    Peter Henke; Fiscal Year: 2009
    ..This proposal will provide important mechanistic insight into the pathophysiology of post-phelbitic syndrome with real potential translation to decreasing the morbidity from this under-acknowledged disease. ..
  49. Clinical and Molecular Evaluation of Cancer Therapy Induced Mucositis
    Sharon Gordon; Fiscal Year: 2007
    ..Demonstration of safety and tolerability will provide a basis to test further this route of administration. Hence, this proposal holds promise for clinical application in a relatively short period. [unreadable] [unreadable]..
  50. Are Volume Standards Accurate Measures of Quality?
    Laurent Glance; Fiscal Year: 2005
    ..abstract_text> ..
  51. Thrombus resolution is CXC chemokine dependent
    Peter Henke; Fiscal Year: 2006
    ..abstract_text> ..