Genomes and Genes
Summary: Percutaneous transabdominal puncture of the uterus during pregnancy to obtain amniotic fluid. It is commonly used for fetal karyotype determination in order to diagnose abnormal fetal conditions.
Publications307 found, 100 shown here
- Amniocentesis results: investigation of anxiety. The ARIA trialJ Hewison
Academic Unit of Psychiatry and Behavioural Sciences, University of Leeds, UK
Health Technol Assess 10:iii, ix-x, 1-78. 2006The Amniocentesis Results: Investigation of Anxiety (ARIA) trial tested two hypotheses: first, that giving amniocentesis results out on a fixed date alters maternal anxiety during the waiting period, compared with a policy of telling ..
- Procedure-related complications of amniocentesis and chorionic villous sampling: a systematic reviewFaris Mujezinovic
Department of Perinatology, University Clinical Center Maribor, Maribor, Slovenia
Obstet Gynecol 110:687-94. 2007To compile a systematic review of complications related to genetic amniocentesis and chorionic villus sampling (CVS) to provide benchmark data for counseling and performance assessment of individual operators.
- Microbial invasion and cytokine response in amniotic fluid in a Swedish population of women with preterm prelabor rupture of membranesBo Jacobsson
Perinatal Center, Department of Obstetrics and Gynecology, Institute for the Health of Women and Children, Sahlgrenska University Hospital, Goteborg, Sweden
Acta Obstet Gynecol Scand 82:423-31. 2003....
- Amniocentesis and mother-to-child human immunodeficiency virus transmission in the Agence Nationale de Recherches sur le SIDA et les Hépatites Virales French Perinatal CohortLaurent Mandelbrot
Assistance Publique Hopitaux de Paris AP HP, Service de Gynecologie Obstetrique, Hopital Louis Mourier, Colombes, and Université Paris 7 Diderot, Paris, France
Am J Obstet Gynecol 200:160.e1-9. 2009The objective of the study was to investigate whether performing an amniocentesis increased mother-to-child transmission of human immunodeficiency virus (HIV)-1 (MTCT).
- Amniotic fluid interleukin-6 and tumor necrosis factor-alpha at mid-trimester genetic amniocentesis: relationship to intra-amniotic microbial invasion and preterm deliveryNikolaos Thomakos
1st Department of Obstetrics and Gynecology, Alexandra Maternity Hospital, Athens University, Athens, Greece
Eur J Obstet Gynecol Reprod Biol 148:147-51. 2010..To determine the value of amniotic fluid interleukin-6 (AF IL-6) and tumor necrosis factor-alpha (AF TNF-alpha) in the diagnosis of microbial invasion of the amniotic cavity and in the prediction of preterm delivery (PTD)...
- An elevated amniotic fluid matrix metalloproteinase-8 level at the time of mid-trimester genetic amniocentesis is a risk factor for spontaneous preterm deliveryB H Yoon
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Korea
Am J Obstet Gynecol 185:1162-7. 2001..angiogenin can identify patients at risk for spontaneous preterm delivery in patients undergoing mid-trimester amniocentesis. STUDY DESIGN: A case-control study was conducted to compare mid-trimester concentrations of amniotic fluid ..
- Clinical significance of intra-amniotic inflammation in patients with preterm labor and intact membranesB H Yoon
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Korea
Am J Obstet Gynecol 185:1130-6. 2001..STUDY DESIGN: Amniocentesis was performed in 206 patients with preterm labor and intact membranes...
- Fetal loss rate after chorionic villus sampling and amniocentesis: an 11-year national registry studyA Tabor
Department of Fetal Medicine, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
Ultrasound Obstet Gynecol 34:19-24. 2009To assess the fetal loss rate following amniocentesis and chorionic villus sampling (CVS).
- Performance characteristics of putative tests for subclinical chorioamnionitisR K Edwards
Department of Obstetrics and Gynecology, University of Florida College of Medicine, Gainesville 32610-0294, USA
Infect Dis Obstet Gynecol 9:209-14. 2001..women in preterm labor at 22-35 weeks gestation with suspected subclinical chorioamnionitis underwent amniocentesis. Amniotic fluid analysis included Gram stain, culture, and determination of glucose, MMP-9, IL-6, and IL-12 ..
- Ultrasound findings before amniocentesis in selecting the method of analysing the sampleKarl O Kagan
Harris Birthright Research Centre for Fetal Medicine, King s College Hospital Medical School, London, UK
Prenat Diagn 27:34-9. 2007To determine if the primary method of cytogenetic analysis in pregnant women undergoing amniocentesis should be quantitative fluorescent polymerase chain reaction (qf-PCR), with karyotyping being performed only on those with abnormal ..
- Chronic viral infections and invasive procedures: risk of vertical transmission and current recommendationsMarta Lopez
Maternal Fetal Medicine Department, Institut Clinic de Ginecologia, Obstetricia i Neonatologia, University of Barcelona, Barcelona, Spain
Fetal Diagn Ther 28:1-8. 2010..The risk of hepatitis B transmission during amniocentesis seems to be low, but it may be increased in women with a positive HBeAg...
- Fetal loss rate and associated risk factors after amniocentesis, chorionic villus sampling and fetal blood samplingC Enzensberger
OB and GYN, Division of Prenatal Medicine, University Gießen and Marburg
Ultraschall Med 33:E75-9. 2012To assess the total and procedure-related fetal loss rate and associated risk factors following amniocentesis (AC), chorionic villus sampling (CVS) and fetal blood sampling (FBS).
- Screening for Down's syndrome: effects, safety, and cost effectiveness of first and second trimester strategiesR E Gilbert
Systematic Reviews Training Unit, Department of Paediatric Epidemiology and Biostatistics, Institute of Child Health, London WC1N 1EH
BMJ 323:423-5. 2001..To compare the effects, safety, and cost effectiveness of antenatal screening strategies for Down's syndrome...
- Mid-trimester amniocentesis fetal loss rateR Douglas Wilson
J Obstet Gynaecol Can 29:586-95. 2007To determine the postprocedure loss rate for mid-trimester genetic amniocentesis.
- Prenatal diagnosis in human immunodeficiency virus-infected women: a new screening program for chromosomal anomaliesOriol Coll
Institut Clinic de Ginecologia, Obstetricia i Neonatologia, Barcelona, Spain
Am J Obstet Gynecol 194:192-8. 2006..This study was undertaken to describe a new prenatal diagnosis program among human immunodeficiency virus (HIV)-infected women, and the perinatal outcome of this program's application over a more than 2-year period...
- Early invasive diagnostic techniques in pregnant women who are infected with the HIV: a multicenter case seriesEdgardo Somigliana
Department of Obstetrics Gynecology and Neonatology, L Mangiagalli Hospital, Milan, Italy
Am J Obstet Gynecol 193:437-42. 2005....
- Individual risk of fetal loss following routine second trimester amniocentesis: a controlled study of 20,460 casesP Kozlowski
Pränatal Medizin und Genetik Duesseldorf
Ultraschall Med 29:165-72. 2008The aim of this study was to evaluate the impact of maternal risk factors on excess fetal loss related to amniocentesis.
- Cervical length and gestational age at admission as predictors of intra-amniotic inflammation in preterm labor with intact membranesM Palacio
Department of Maternal Fetal Medicine, Institute Clinic of Gynecology, Obstetrics and Neonatology, Barcelona, Spain
Ultrasound Obstet Gynecol 34:441-7. 2009..To evaluate cervical length and gestational age as predictors of intra-amniotic inflammation in patients admitted because of preterm labor and intact membranes...
- Antibiotic prophylaxis before second-trimester genetic amniocentesis (APGA): a single-centre open randomised controlled trialClaudio Giorlandino
Department of Prenatal Diagnosis, Artemisia Fetal Maternal Medical Centre, Rome, Italy
Prenat Diagn 29:606-12. 2009To compare procedure-related pregnancy loss after second-trimester genetic amniocentesis in women given an antibiotic prophylaxis and controls.
- Diagnostic mid trimester amniocentesis: how safe?John W Seeds
Department of Obstetrics and Gynecology, Virginia Commonwealth University, Richmond, VA 23298, USA
Am J Obstet Gynecol 191:607-15. 2004Genetic mid-trimester amniocentesis is a common invasive procedure. The origin of the commonly quoted 0...
- IGFBP-1 levels in cervicovaginal secretions before and after amniocentesisR Devlieger
Division of Obstetrics and Fetal Medicine, Department of Obstetrics and Gynecology, Katholieke Universiteit Leuven, Leuven, Belgium
Gynecol Obstet Invest 67:9-13. 2009To evaluate the levels of insulin-like growth factor-binding protein-1 (IGFBP-1) in cervicovaginal secretions before and after midtrimester amniocentesis and relate to clinical outcome.
- Pregnancy loss rate after mid-trimester amniocentesis in twin pregnanciesAlison G Cahill
Department of Obstetrics and Gynecology, Washington University School of Medicine, St Louis, MO, USA
Am J Obstet Gynecol 200:257.e1-6. 2009The purpose of this study was to estimate the attributable pregnancy loss rate of mid-trimester amniocentesis in twin pregnancies.
- Comparison of multiplex ligation-dependent probe amplification and karyotyping in prenatal diagnosisElisabeth M Boormans
Academic Medical Center Amsterdam, Amsterdam, The Netherlands
Obstet Gynecol 115:297-303. 2010....
- Effect of pre-amniocentesis counseling on maternal pain and anxietyOsman Balci
Department of Obstetrics and Gynecology, Meram Medicine Faculty, Selcuk University, Konya, Turkey
J Obstet Gynaecol Res 37:1828-32. 2011..of anticipated and perceived pain and anxiety in expectant mothers at the times of pre-counseling, post-counseling, and post-amniocentesis and to investigate the effect of pre-amniocentesis counseling on the level of pain and anxiety.
- Maternal mortality following diagnostic 2nd-trimester amniocentesisUriel Elchalal
Department of Obstetrics and Gynecology, Hadassah University Hospital, Eim Kerem, Hebrew University, Jerusalem, Israel
Fetal Diagn Ther 19:195-8. 2004We present 2 cases of maternal mortality after transabdominal amniocentesis performed during the 2nd trimester of pregnancy. In both these cases, blood cultures revealed Escherichia coli...
- Phthalates and perfluorooctanesulfonic acid in human amniotic fluid: temporal trends and timing of amniocentesis in pregnancyMorten Søndergaard Jensen
Danish Ramazzini Centre, Department of Occupational Medicine, Aarhus University Hospital, Aarhus, Denmark
Environ Health Perspect 120:897-903. 2012..Measures of prenatal environmental exposures are important, and amniotic fluid levels may directly reflect fetal exposures during hypothesized windows of vulnerability...
- Gender differences in amniotic fluid cytokine levelsS H Poggi
Department of Obstetrics and Gynecology, Georgetown University Hospital, 3800 Reservoir Road, Washington, DC 20007, USA
J Matern Fetal Neonatal Med 15:367-71. 2004..We investigated whether fetal gender affects amniotic fluid levels of the inflammatory cytokines interleukin (IL)-6 and IL-10 and the pro-angiogenesis cytokine angiogenin...
- Fetal loss associated with second trimester amniocentesisSomsri Pitukkijronnakorn
Maternal Fetal Medicine Unit, Department of Obstetrics and Gynaecology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok 10400, Thailand
Arch Gynecol Obstet 284:793-7. 2011To evaluate the fetal loss rate associated with second trimester amniocentesis.
- Dimeric inhibins in amniotic fluid, maternal serum, and fetal serum in human pregnancyE M Wallace
Department of Obstetrics and Gynecology, University of Edinburgh, United Kingdom
J Clin Endocrinol Metab 82:218-22. 1997..Further, the presence of inhibin B in male fetuses is consistent with a testicular origin, suggesting that inhibin B may be important in the development of the fetal hypothalamo-pituitary-testicular axis...
- A short cervix in women with preterm labor and intact membranes: a risk factor for microbial invasion of the amniotic cavityRicardo Gomez
Center for Perinatal Diagnosis and Research CEDIP, Sotero del Rio Hospital, P Universidad Catolica de Chile, Puente Alto, Chile
Am J Obstet Gynecol 192:678-89. 2005..The purpose of this study was to determine whether there was a relationship between sonographic cervical length and the presence of culture-proven microbial invasion of the amniotic cavity in women with preterm labor and intact membranes...
- Information and decision support needs of parents considering amniocentesis: interviews with pregnant women and health professionalsMarie Anne Durand
Department of Primary Care and Public Health, School of Medicine, Cardiff University, Cardiff, UK
Health Expect 13:125-38. 2010Our aim was to clarify and categorize information and decision support needs of pregnant women deciding about amniocentesis.
- Women of advanced maternal age undergoing amniocentesis: a period of uncertaintyJui Chiung Sun
School of Nursing, National Yang Ming University, Taipei, Taiwan
J Clin Nurs 17:2829-37. 2008To generate a descriptive model for understanding patterns and interpretations concerning women's experiences of amniocentesis in Taiwan.
- Outcome of twin pregnancies after amniocentesisAnita Sik Yau Kan
Department of Obstetrics and Gynaecology, The University of Hong Kong, Queen Mary Hospital, Hospital, Hong Kong, China
J Obstet Gynaecol Res 38:376-82. 2012The aim of this study was to assess the miscarriage and fetal loss rates of twin pregnancies after amniocentesis.
- Cortisol and anxiety response to a relaxing intervention on pregnant women awaiting amniocentesisT Ventura
Hospital Dona Estefânia, Centro Hospitalar de Lisboa Central, Rua Jacinta Marto, 1169 045 Lisbon, Portugal
Psychoneuroendocrinology 37:148-56. 2012..However, medication for stress may carry risks to the expectant mother, therefore the efficacy of non-pharmacological interventions should be investigated...
- Risks of third-trimester amniocentesisIvica Zalud
Department of Obstetrics Gynecology and Women s Health, Kapiolani Medical Center for Women and Children, John A Burns School of Medicine, University of Hawaii, 13419 Punahou Street, Honolulu, HI 96734, USA
J Reprod Med 53:45-8. 2008To establish the risk of immediate complications from third-trimester amniocentesis.
- Psychological response to prenatal genetic counseling and amniocentesisK P Tercyak
Department of Clinical and Health Psychology, University of Florida, Gainesville, FL, USA
Patient Educ Couns 43:73-84. 2001..women at increased risk for fetal genetic anomalies who were referred for prenatal genetic counseling and amniocentesis; to determine which of these factors would predict amniocentesis use; and to identify patient outcomes ..
- Amniotic fluid testosterone: relationship with cortisol and gestational ageP Sarkar
Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, London, UK
Clin Endocrinol (Oxf) 67:743-7. 2007..Although best investigated in foetal plasma, this is now difficult because of the decline in frequency of foetal blood sampling; in this study, we used amniotic fluid as a biomarker to investigate foetal exposure...
- Amniotic fluid matrix metalloproteinase-9 and interleukin-6 in predicting intra-amniotic infectionHassan Harirah
Department of Obstetrics and Gynecology, The University of Texas Medical Branch, Galveston, Texas 77555 0587, USA
Obstet Gynecol 99:80-4. 2002..To assess the potential role of amniotic fluid (AF) matrix metalloproteinase-9 and interleukin-6 in predicting intra-amniotic infection...
- Amniotic fluid interleukin-18 at mid-trimester genetic amniocentesis: relationship to intraamniotic microbial invasion and preterm deliveryG Daskalakis
First Department of Obstetrics and Gynaecology, Alexandra Maternity Hospital, and Department of Biological Chemistry, Athens University, Athens, Greece
BJOG 116:1743-8. 2009..To determine the value of amniotic fluid interleukin-18 (AF IL-18) in the diagnosis of microbial invasion of the amniotic cavity and prediction of preterm delivery (PTD)...
- Multiplex ligation-dependent probe amplification versus karyotyping in prenatal diagnosis: the M.A.K.E. studyElisabeth M A Boormans
Department of Obstetrics and Gynecology, Academic Medical Centre, Amsterdam, The Netherlands
BMC Pregnancy Childbirth 8:18. 2008..Multiplex ligation-dependent probe amplification (MLPA) is a new molecular genetic technique in prenatal diagnosis. Previous preclinical evidence suggests equivalence of MLPA and traditional karyotyping (TKT) regarding test performance...
- Rapid aneuploidy screening (FISH or QF-PCR): the changing scene in prenatal diagnosis?W C Leung
Prenatal Diagnostic and Counseling Department, Tsan Yuk Hospital, University of Hong Kong, Hong Kong SAR, China
Expert Rev Mol Diagn 4:333-7. 2004..The ten most recent studies from the literature within this research theme are reviewed and the pros and cons of this new approach in prenatal diagnosis are discussed, including the suggestion of future studies...
- Economic evaluation of prenatal diagnosis: a methodological reviewP Shackley
Health Economics Research Unit, Department of Public Health, Foresterhill, Aberdeen
Prenat Diagn 16:389-95. 1996..The various methods of economic evaluation are discussed in the context of amniocentesis and chorionic villus sampling...
- Infant morbidity following amniocentesis and chorionic villus sampling for prenatal karyotypingMaria Cederholm
Department of Women s and Children s Health, Section of Obstetrics and Gynaecology, Uppsala University, SE 751 85 Uppsala, Sweden
BJOG 112:394-402. 2005To investigate whether amniocentesis and chorionic villus sampling increase the risk of postural deformities, limb reduction defects, respiratory problems in the newborn, fetal and infant mortality, prematurity, low birthweight and fetal ..
- A sonographic short cervix as the only clinical manifestation of intra-amniotic infectionSonia Hassan
Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, Wayne State University, Hutzel Women s Hospital, 3990 John R, 7 Brush North, MFM Mail Drawer 163, Detroit, MI 48201, USA
J Perinat Med 34:13-9. 2006..This study was conducted to determine the rate of MIAC and intra-amniotic inflammation in patients with a cervical length < 25 mm in the mid-trimester...
- Chorioamnionitis and intrauterine fetal death after second-trimester amniocentesisMarguerite Vigliani
Women and Infants Hospital, Department of Obstetrics and Gynecology, Warren Alpert School of Medicine at Brown University, Providence, RI, USA marguerite_vigliani brown edu
Fetal Diagn Ther 26:216-8. 2009We report an intrauterine fetal death that occurred less than 24 h after transabdominal amniocentesis. Chorioamnionitis was confirmed by amniotic fluid culture which showed multiple enteric organisms and postmortem examination of the ..
- Cell-free fetal DNA in maternal circulation after amniocentesisOsamu Samura
Department of Obstetrics and Gynecology, Hiroshima University Faculty of Medicine, 1 2 3 Kasumi, Minami Ku, Hiroshima 734 8551, Japan
Clin Chem 49:1193-5. 2003
- Congenital toxoplasmosis: necessity of clinical and ultrasound follow-up despite negative amniocentesisIsabelle Villena
Prenat Diagn 23:1098-9. 2003
- Chorionic villus sampling and amniocentesisBruno Brambati
Center of Prenatal Diagnosis, Milan, Italy
Curr Opin Obstet Gynecol 17:197-201. 2005..The advantages and disadvantages of common invasive methods for prenatal diagnosis are presented in light of new investigations...
- Rapid detection of chromosomal aneuploidies in uncultured amniocytes by multiplex ligation-dependent probe amplification (MLPA)R Hochstenbach
Department of Biomedical Genetics, University Medical Center Utrecht, The Netherlands
Prenat Diagn 25:1032-9. 2005..To test whether multiplex ligation-dependent probe amplification (MLPA) can be used for the detection of aneuploidy of chromosomes 13, 18, 21, X, and Y in uncultured amniocytes...
- Detection of chromosome aberrations in the second trimester using genetic amniocentesis: experience during 1995-2004Jenn Jhy Tseng
Department of Obstetrics and Gynecology, Taichung Veterans General Hospital, Hung Kuang University, Taichung, and Institute of Clinical Medicine, National Yang Ming University, Taipei, Taiwan
Taiwan J Obstet Gynecol 45:39-41. 2006To retrospectively investigate the 10-year experience of prenatal diagnosis of fetal chromosome aberrations by second-trimester amniocentesis.
- Chorionic villus sampling compared with amniocentesis and the difference in the rate of pregnancy lossAaron B Caughey
Division of Perinatal Medicine and Genetics, Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, San Francisco, California, USA
Obstet Gynecol 108:612-6. 2006To compare loss rates following amniocentesis and chorionic villus sampling (CVS) over time.
- Techniques for chorionic villus sampling and amniocentesis: a survey of practice in specialist UK centresA J Carlin
Department of Obstetrics and Gynaecology, Liverpool Women s Hospital, Liverpool, UK
Prenat Diagn 28:914-9. 2008Guidelines exist for amniocentesis and chorionic villous sampling (CVS) practice, but there is no consensus regarding individual techniques. Our survey sought to review current practice within specialist centres in the United Kingdom.
- Rapid prenatal diagnostic testing for Down syndrome only or longer wait for full karyotype: the views of pregnant womenMandy Ryan
Health Economics Research Unit, University of Aberdeen, Foresterhill, Aberdeen AB25 2ZD, Scotland, UK
Prenat Diagn 25:1206-11. 2005..This study investigates the value pregnant women place on these alternative prenatal diagnostic tests...
- [Genetic amniocentesis in high-risk populations. Experience in 3081 cases]Mabel Cerrillo Hinojosa
Clinica de Reproducción y Genetica Hospital Angeles del Pedregal
Ginecol Obstet Mex 77:173-82. 2009..However, Mexico has been performed only in private hospitals and the National Medical Center November 20 ISSSTE and the National Institute of Perinatology...
- Amniocentesis in twin pregnancies: a systematic review of the literatureJoy Vink
Department of Ob Gyn, Division of Maternal Fetal Medicine, Columbia University Medical Center, New York, NY 347 880 2492 USA
Prenat Diagn 32:409-16. 2012Using published data, we sought to determine the amniocentesis-related loss rate in twin gestations.
- Does indomethacin prevent preterm birth in women with cervical dilatation in the second trimester?Vincenzo Berghella
Departments of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
Am J Perinatol 26:13-9. 2009..23, 1.14) suggested a possible but not significant benefit for indomethacin use. Indomethacin therapy in women with dilated cervix at 14 (0)/ (7) to 25 (6)/ (7) weeks, regardless of cerclage or not, had no effect on pregnancy outcomes...
- Elevated amniotic fluid C-reactive protein at the time of genetic amniocentesis is a marker for preterm deliveryFabio Ghezzi
Department of Obstetrics and Gynecology, University of Insubria, Circolo Hospital, Varese, Italy
Am J Obstet Gynecol 186:268-73. 2002..The objective of this study was to investigate whether the amniotic fluid C-reactive protein level at the time of genetic amniocentesis is a marker for spontaneous preterm delivery before 34 and 37 weeks of gestation.
- A case of successful management of maternal septic shock with multiple organ failure following amniocentesis at midgestationJunzo Hamanishi
Department of Gynecology and Obstetrics, Kyoto University Graduate School of Medicine, Japan
J Obstet Gynaecol Res 28:258-61. 2002Maternal sepsis is an unusual but catastrophic complication of amniocentesis. We report a case of successful treatment of maternal septic shock and multiple organ failure following amniocentesis at midgestation, possibly due to needle ..
- Revisiting the fetal loss rate after second-trimester genetic amniocentesis: a single center's 16-year experienceAnthony O Odibo
Division of Maternal Fetal Medicine, Ultrasound and Genetics, Department of Obstetrics and Gynecology, Washington University in St Louis, Missouri 63110, USA
Obstet Gynecol 111:589-95. 2008To estimate an institution's specific fetal loss rate after a second-trimester genetic amniocentesis.
- How unexpected are unexpected findings in prenatal cytogenetic diagnosis? A literature reviewMyra C B van Zwieten
Academic Medical Center University of Amsterdam, Division Clinical Methods and Public Health, Department of General Practice Family Medicine, P O Box 22700, 1100 DE Amsterdam, The Netherlands
Eur J Obstet Gynecol Reprod Biol 120:15-21. 2005..Before targeted testing can be applied it is necessary to establish exact criteria in order to discern unexpected findings from standard testing results...
- Racial-ethnic differences in genetic amniocentesis uptakeJennifer B Saucier
Genzyme Genetics, Austin, Texas 78628, USA
J Genet Couns 14:189-95. 2005The objective of this study was to determine the role of health beliefs in genetic amniocentesis acceptance in a diverse racial-ethnic population...
- Assessment of maternal anxiety levels before and after amniocentesisC C M Ng
Department of Maternal Foetal Medicine, KK Women s and Children s Hospital, 100 Bukit Timah Road, Singapore
Singapore Med J 45:370-4. 2004To assess anxiety levels in mothers before and after undergoing amniocentesis. The secondary aim was to see how counselling by nurse-counsellors affected maternal anxiety levels.
- Ethnicity, bioethics, and prenatal diagnosis: the amniocentesis decisions of Mexican-origin women and their partnersC H Browner
Department of Psychiatry and Biobehavioral Sciences, University of California, Los Angeles 90024 1759, USA
Am J Public Health 89:1658-66. 1999..include ethnic minority women, who, with the exception of women from certain Asian groups, refuse amniocentesis at significantly higher rates than others...
- Maternal anxiety at amniocentesis and plasma cortisolP Sarkar
Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Campus, UK
Prenat Diagn 26:505-9. 2006To assess whether anticipation of amniocentesis is linked with maternal anxiety, and whether this anxiety is associated with increased maternal plasma cortisol.
- Clostridium welchii infection following amniocentesis: a case report and review of the literatureH Hamoda
Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford, UK
Prenat Diagn 22:783-5. 2002We report a case of severe Clostridium welchii infection following amniocentesis with septicaemia, haemolysis, DIC, pulmonary oedema and renal failure...
- Genetic amniocentesis: a risk factor for preterm delivery?Emanuela Medda
Department of Epidemiology and Biostatistics, Istituto Superiore di Sanita, Viale Regina Elena 299, 00161, Rome, Italy
Eur J Obstet Gynecol Reprod Biol 110:153-8. 2003To determine whether genetic amniocentesis performed in the second trimester of pregnancy is associated with the risk of preterm delivery.
- Prenatal diagnosis by amniocentesis and chorionic villus biopsy of mtDNA mutation 8993T > GR Pettman
Maritime Medical Genetics Service, IWK Health Centre, Halifax, Nova Scotia, Canada
J Inherit Metab Dis 30:404. 2007..She underwent prenatal testing by both CVS and amniocentesis of the 8993T > G heteroplasmy levels. This is the first reported case in which both procedures were used...
- A review of decision support technologies for amniocentesisM A Durand
Department of Primary Care and Public Health, School of Medicine, Cardiff University, Neuadd Meirionnydd, Health Park CF14 4YS, UK
Hum Reprod Update 14:659-68. 2008..The purpose of this review was to describe and evaluate existing DSTs for amniocentesis testing.
- Fetal loss after amniocentesis in a series of 5,780 proceduresP Gaudry
Department of Obstetrics and Gynecology, Hopital d Instruction des armees BEGIN, Saint Mande, France
Fetal Diagn Ther 23:217-21. 2008Counseling on prenatal diagnosis requires accurate knowledge of the associated risks, including fetal loss. The objective of our study was to assess this risk of amniocentesis in a single center with several operators.
- Amniocentesis and women with hepatitis B, hepatitis C, or human immunodeficiency virusGregory Davies
J Obstet Gynaecol Can 25:145-48, 149-52. 2003To review the risk of in utero infection through amniocentesis in women with hepatitis B, hepatitis C, or human immunodeficiency virus (HIV).
- Value of amniocentesis versus fetal tissue for cytogenetic analysis in cases of fetal demiseAnn E Bryant Borders
Division of Maternal Fetal Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA
Fetal Diagn Ther 26:81-4. 2009..We reviewed our ongoing use of amniocentesis prior to uterine evacuation to determine if this provided a better source of cells for cytogenetic analysis.
- Fetal toxoplasmosis and negative amniocentesis: necessity of an ultrasound follow-upFrançoise Gay-Andrieu
Laboratoire de Parasitologie et Pathologie Exotique, Hopital de la Croix Rousse, 93 Grande Rue de la Croix Rousse, 69317 Lyon Cedex 04, France
Prenat Diagn 23:558-60. 2003..These observations confirm the necessity to continue a monthly ultrasound follow-up, even if amniocentesis is negative, in case of fetal toxoplasma infection in pregnancy.
- HIV detection in amniotic fluid samples. Amniocentesis can be performed in HIV pregnant women?Vicente Maiques
Obstetric Service, Hospital Maternal La FE, 5 degrees Planta, Avda Campanar 21, 46009, Valencia, Spain
Eur J Obstet Gynecol Reprod Biol 108:137-41. 2003To assess amniotic fluid (AF) HIV contamination as a marker of intrauterine HIV infection and to evaluate amniocentesis as a risk factor for vertical HIV transmission when the mother was under antiretroviral treatment.
- Chorionic villus sampling and amniocentesis in 2008Mark I Evans
Fetal Medicine Foundation of America, New York, New York, USA
Curr Opin Obstet Gynecol 20:164-8. 2008..have been wide discrepancies between quoted risks of diagnostic procedures (chorionic villus sampling and amniocentesis) yet little properly controlled and randomized data to back often dogmatic assertions...
- The clinical significance of detecting Ureaplasma urealyticum by the polymerase chain reaction in the amniotic fluid of patients with preterm laborBo Hyun Yoon
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea
Am J Obstet Gynecol 189:919-24. 2003..This study was undertaken to determine the clinical significance of a detection of Ureaplasma urealyticum by using the polymerase chain reaction (PCR) in the amniotic fluid of patients with preterm labor and intact membranes...
- Rapid prenatal diagnosis of aneuploidies and zygosity in multiple pregnancies by amniocentesis with single insertion of the needle and quantitative fluorescent PCRVincenzo Cirigliano
Department of Molecular Genetics, General Lab, Barcelona, Spain
Prenat Diagn 23:629-33. 2003....
- Endoscopic laser surgery versus serial amnioreduction for severe twin-to-twin transfusion syndromeMarie Victoire Senat
Department of Obstetrics and Gynecology, Université Paris Ouest Versailles St Quentin, Centre Hospitalier Intercommunale Poissy St Germain, Poissy, France
N Engl J Med 351:136-44. 2004..We conducted a randomized trial to compare the efficacy and safety of these two treatments...
- Human cytomegalovirus (HCMV) DNAemia in the mother at amniocentesis as a risk factor for iatrogenic HCMV infection of the fetusMaria Grazia Revello
Servizio di Virologia, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy
J Infect Dis 197:593-6. 2008..73 mothers of uninfected fetuses and 22 (37%) of 59 mothers of infected fetuses were HCMV DNAemia-positive at amniocentesis. Of the 8 mothers of the 8 fetuses with false-negative amniocentesis results, 4 were DNAemia-positive and 4 ..
- Pregnancy loss rate following routine genetic amniocentesis at Wellington HospitalMichel Sangalli
Department of Obstetrics and Gynaecology, Wellington School of Medicine and Health Sciences CCDHB, Wellington Women s Hospital, Wellington, New Zealand
N Z Med J 117:U818. 2004To determine the institutional pregnancy loss rate following second-trimester genetic amniocentesis.
- Mid-trimester amniocentesis and antibiotic prophylaxisDandolo Gramellini
Department of Gynecology, Obstetrics and Neonatology, University of Parma, Parma, Italy
Prenat Diagn 27:956-9. 2007Assuming that the rate of fetal loss after amniocentesis may be reduced in patients receiving antibiotic prophylaxis, we conducted a retrospective study on untreated versus treated patients receiving prophylactic antibiotics (amoxicillin/..
- Incorporating first-trimester Down syndrome studies into prenatal screening: executive summary of the National Institute of Child Health and Human Development workshopUma M Reddy
Pregnancy and Perinatology Branch, National Institute of Child Health and Human Development, National Institutes of Health, Department of Health and Human Services, Bethesda, Maryland 20892 7510, USA
Obstet Gynecol 107:167-73. 2006..These requirements include training and quality control standards for first-trimester nuchal translucency measurement and laboratory assays, access to chorionic villus sampling, and appropriate counseling regarding screening options...
- C-reactive protein concentration in vaginal fluid as a marker for intra-amniotic inflammation/infection in preterm premature rupture of membranesSoon Sup Shim
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea
J Matern Fetal Neonatal Med 18:417-22. 2005....
- Age-specific risk of fetal loss post second trimester amniocentesis: analysis of 5043 casesVincenzo Mazza
Prenatal Medicine Unit, Department of Obstetrics and Gynecology, Modena and Reggio Emilia University, Italy
Prenat Diagn 27:180-3. 2007To assess the risk of fetal loss attributable to second trimester amniocentesis in singleton pregnancies through a cross-sectional study.
- Routine assessment of amniotic fluid alpha-Fetoprotein in early second-trimester amniocentesis is no longer justifiedKjerstin Ferm Widlund
Department of Obstetrics and Gynecology, Vrinnevi Hospital, Centre of Pediatrics and Obstetrics in Ostergötland, Norrkoping, Sweden
Acta Obstet Gynecol Scand 86:167-71. 2007..years there has been a routine to measure amniotic fluid alpha-Fetoprotein in conjunction with early genetic amniocentesis. The efficacy of such a screening test in a low-risk population has been questioned but never evaluated in a ..
- Does local anesthesia decrease pain perception in women undergoing amniocentesis?Michael C Gordon
Department of Obstetrics and Gynecology, Wilford Hall United Stated Air Force Medical Center, Lackland Air Force Base, TX, USA
Am J Obstet Gynecol 196:55.e1-4. 2007The null hypothesis is that local anesthesia does not decrease pain perception during amniocentesis.
- An elevated maternal plasma, but not amniotic fluid, soluble fms-like tyrosine kinase-1 (sFlt-1) at the time of mid-trimester genetic amniocentesis is a risk factor for preeclampsiaChan Wook Park
Department of Obstetrics and Gynecology, Seoul National University College of Medicine, Seoul, Korea
Am J Obstet Gynecol 193:984-9. 2005..The purpose of this study was to determine if an elevated concentration of soluble fms-like tyrosine kinase-1(sFlt-1) in maternal plasma and amniotic fluid is a risk factor for the subsequent development of preeclampsia...
- Prenatal detection of Down's syndrome by rapid aneuploidy testing for chromosomes 13, 18, and 21 by FISH or PCR without a full karyotype: a cytogenetic risk assessmentAllan Caine
Regional Cytogenetics Unit, St James University Hospital, Leeds, UK
Lancet 366:123-8. 2005..The UKNSC also recommended that FISH or PCR tests should only include trisomies 13, 18, and 21. We undertook a retrospective cytogenetic audit to assess the probable clinical effect of these proposed policy changes...
- Proteomic biomarkers that predict the clinical success of rescue cerclageCarl P Weiner
Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD 21201 1559, USA
Am J Obstet Gynecol 192:710-8. 2005..We tested amniotic fluid from women who were preparing to undergo rescue cerclage for proteomic biomarkers and correlated their presence with clinical outcome...
- FastFISH: technique for ultrarapid fluorescence in situ hybridization on uncultured amniocytes yielding results within 2 h of amniocentesisM Choolani
Diagnostic Biomarker Discovery Laboratory, Division of Maternal and Fetal Medicine, Department of Obstetrics and Gynaecology, Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, 119074 Singapore
Mol Hum Reprod 13:355-9. 2007..fluorescence in situ hybridization (FISH) method (FastFISH) that releases accurate results on the same day as amniocentesis. FastFISH was optimized to be completed within 2 h of sample collection using CEP and LSI probes for ..
- Prenatal diagnostic testing and Down Syndrome in Victoria 1992--2002Evelyne E Muggli
Public Health Genetics, Murdoch Childrens Research Institute, Royal Children s Hospital, Victoria
Aust N Z J Public Health 28:465-70. 2004..To describe patterns of uptake of prenatal diagnostic testing and prenatal detection rates for Down syndrome in Victoria with regard to maternal age and prenatal screening practices...
- Risk factors for procedure-related fetal losses after mid-trimester genetic amniocentesisChoy Wah Kong
Fetal Medicine Unit, Department of Obstetrics and Gynaecology, Prince of Wales Hospital, The Chinese University of Hong Kong Shatin, Hong Kong SAR, China
Prenat Diagn 26:925-30. 2006..of this study was to determine the institutional pregnancy loss rate following second-trimester genetic amniocentesis and to ascertain whether factors exist which would identify pregnancies at increased risk of having a ..
- Proteomic biomarker analysis of amniotic fluid for identification of intra-amniotic inflammationIrina A Buhimschi
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale University, New Haven, Connecticut 06520 8063, USA
BJOG 112:173-81. 2005..We applied proteomic technology (SELDI: surface-enhanced laser desorption ionisation) to identify the proteomic profile of intra-amniotic inflammation...
- Doppler ultrasonography versus amniocentesis to predict fetal anemiaDick Oepkes
Department of Obstetrics, Leiden University Medical Center, Leiden, The Netherlands
N Engl J Med 355:156-64. 2006Pregnancies complicated by Rh alloimmunization have been evaluated with the use of serial invasive amniocentesis to determine bilirubin levels by measuring in the amniotic fluid the change in optical density at a wavelength of 450 nm (..
- Proteomics technology for the accurate diagnosis of inflammation in twin pregnanciesIrina A Buhimschi
Yale University School of Medicine, New Haven, Connecticut 06520 8063, USA
BJOG 112:250-5. 2005
- Pregnancy loss rates after midtrimester amniocentesisKeith A Eddleman
Mount Sinai School of Medicine, New York, New York, USA
Obstet Gynecol 108:1067-72. 2006The purpose of this study was to quantify the contemporary procedure-related loss rate after midtrimester amniocentesis using a database generated from patients who were recruited to the First And Second Trimester Evaluation of Risk for ..
- Complications of third-trimester amniocentesis using continuous ultrasound guidanceMichael C Gordon
Wilford Hall Medical Center, Lackland Air Force Base, Texas, USA
Obstet Gynecol 99:255-9. 2002The objective of the study was to estimate the risks of third-trimester amniocentesis with continuous ultrasound guidance.
- Decisions about amniocentesis by advanced maternal age patients following maternal serum screening may not always correlate clinically with screening results: need for improvement in informed consent processTina Marini
Baystate Medical Center, Laboratory Genetics, Western Campus Tuft Medical School, Springfield, Massachusetts, USA
Am J Med Genet 109:171-5. 2002..who underwent serum screening to assess how screening results correlated with their decisions regarding amniocentesis. A 6-year review (1994-1999) of laboratory records identified 2,456 AMA patients who underwent multiple-marker ..
- Accuracy of the TDx-FLM assay of amniotic fluid: a comparison of vaginal pool samples with amniocentesisJ Cleary-Goldman
Department of Obstetrics and Gynecology, Columbia Presbyterian Medical Center, New York, New York, USA
J Matern Fetal Neonatal Med 11:374-7. 2002..The purpose of this study was to evaluate the use of the TDx-FLM fluorescence polarization assay on vaginal pool fluid in patients with preterm premature rupture of membranes (PPROM)...
- The diagnostic performance of cytogenetic investigation in amniotic fluid cells and chorionic villiF J Los
Department of Clinical Genetics, University Hospital Dijkzigt, Erasmus University, Rotterdam, The Netherlands
Prenat Diagn 21:1150-8. 2001First-trimester chorionic villus sampling has not reached the popularity of second-trimester amniocentesis in prenatal cytogenetic diagnosis, in contrast to initial expectations...
- Health-related quality-of-life assessment of prenatal diagnosis: chorionic villi sampling and amniocentesisDavid Feeny
Institute of Health Economics, Edmonton, Alberta, Canada
Genet Test 6:39-46. 2002..study assesses the health-related quality-of-life (HRQL) effects of chorionic villi sampling (CVS) and genetic amniocentesis (GA), including both process and outcomes of prenatal diagnosis...
- Comparison of the use of amniocentesis in two countries with different policies for prenatal testing: the case of France and the United StatesBabak Khoshnood
Epidemiological Research Unit on Perinatal and Women s Health, INSERM U149, France
Prenat Diagn 25:14-9. 2005To compare maternal age- and education-specific use of amniocentesis in France and the United States.
- F.nucleatum in Amniotic Fluid InfectionYiping Han; Fiscal Year: 2004..nucleatum infection in AF. AF samples will be collected via amniocentesis from 400 patients in preterm labor with intact fetal membranes at a gestational age of < 32 weeks...
- Non-Invasive Detection of Fetal Aneuploidy by Next-Generation DNA SequencingDAVID GERARD PETERS; Fiscal Year: 2013..Definitive diagnosis is then undertaken using interventional procedures such as amniocentesis and chorionic villus sampling (CVS) that obtain fetal or placental cells, respectively, for karyotype analysis...
- Genetic Analysis of Human First Trimester Trophoblast in Ongoing PregnanciesMichael Peter Diamond; Fiscal Year: 2013..The most common methods of retrieving fetal tissue for prenatal diagnosis, amniocentesis and chorionic villous sampling, are invasive, with a risk of fetal loss...
- Insulin Producing Cells from Amniotic Stem Cells for Diabetes TherapyAnthony Atala; Fiscal Year: 2009..NHP AFS cell lines will be derived after amniocentesis of pregnant mothers...
- Non-invasive Aneuploidy Screening of Circulating Fetal Cells for Prenatal DiagnosMatthew Rabinowitz; Fiscal Year: 2012..Although the widely used first trimester chorionic villus sampling (CVS) and second trimester amniocentesis are relatively safe, both procedures are not without negligible risks...
- Rapid non-invasive prenatal Down syndrome detection using a DNA-molecule counterGlenn Fu; Fiscal Year: 2013..and blood sample measurements are inaccurate, and confirmatory tests such as chorionic villus sampling and amniocentesis are invasive procedures that can cause miscarriage...
- Co-Operative Multicenter Trials in Obstetrics &Maternal Fetal MedicineYoram Sorokin; Fiscal Year: 2013..will reduce the risk of spontaneous preterm birth (SPTB) among women that (Uu) undergo mid-trimester genetic amniocentesis for clinical indications, and have Ureaplasma urealyticum detected in amniotic fluid, by polymerase chain ..
- Novel Optical Technique for Recovery of Fetal Cells in Maternal BloodLev T Perelman; Fiscal Year: 2012Project Summary Present cell-based techniques of prenatal diagnosis such as amniocentesis, chorionic villus sampling (CVS) and percutaneous umbilical blood sampling (PUBS) are invasive and present significant risks of fetal loss...
- COMPARISON OF CHORION VILLUS SAMPLING AND AMNIOCENTESISROBERT DESNICK; Fiscal Year: 1990..comparing the safety and accuracy of chorionic villus sampling (CVS) in the first trimester of pregnancy with amniocentesis in the second trimester for the prenatal diagnosis of genetic disorders...
- PRENATAL DOWN SYNDROME SCREENINGRachel Fisher; Fiscal Year: 1993..The risk of delivering a baby with Down syndrome (DS) increases with increasing maternal age . By offering amniocentesis to women 35 and over, approximately 20% of DS pregnancies can be detected...
- FETAL ERYTHROID CELLS IN MATERNAL CIRCULATIONSTEPHEN GRANT; Fiscal Year: 1999..Such a maternal blood test could ultimately complement, or perhaps even replace such invasive procedures as amniocentesis and chorionic villus sampling...
- IN SITU HYBRIDIZATION IN PRENATAL DIAGNOSISKenneth Castleman; Fiscal Year: 1993..techniques for detecting the most commonly occurring cytogenetic abnormalities in interphase cells obtained by amniocentesis or chorionic villus sampling (CVS)...
- COMPARISON OF CHORION VILLUS SAMPLING AND AMNIOCENTESISEugene Pergament; Fiscal Year: 1990..overall aim of this proposal is to compare the safety and the accuracy of Chorionic Villi Sampling (CVS) with amniocentesis by means of a multicenter, cooperative clinical study...
- Miniature Laser Therapy EndoscopeGuillermo Tearney; Fiscal Year: 2009..of our device will be 350 [unreadable]m, small enough to be introduced into the amniotic cavity through an amniocentesis needle (22-gauge), which should provide a 10-fold reduction in complication rate...
- EVALULATION OF PRENATAL TESTS FOR CHROMOSOMAL DISORDERSA Washington; Fiscal Year: 1993..of the appropriate clinical use of prenatal diagnostic tests for chromosomal abnormalities, focusing on amniocentesis and chorionic villus sampling (CVS)...
- IMPROVED CLASSIFIERS FOR AUTOMATED MULTIPLEX FISHKenneth Castleman; Fiscal Year: 2001..fully and test the system in routine clinical use on prenatal, postnatal and cancer specimens from amniocentesis, peripheral blood, and bone marrow...
- Holographic Sonic Flashlighlt for Guiding Interventional ProceduresGeorge Stetten; Fiscal Year: 2009..Thus certain ultrasound-guided procedures such as liver biopsy and amniocentesis are not practical with the SF, because attaching such a large display would make a hand-held transducer ..
- COMPARISON OF CHORION VILLUS SAMPLING AND AMNIOCENTESISDavid Ledbetter; Fiscal Year: 1990b>Amniocentesis for prenatal diagnosis is currently utilized by 30 to 40 percent of women becoming pregnant over age 35. It's safety and accuracy are well documented. However, it can not be performed until 16 weeks gestation...
- The demographic trajectory of the sex ratio in human pregnancySTEVEN ORZACK; Fiscal Year: 2009..the sex ratio at a defined time just after conception, 2) analyze data from chorionic-villus sampling and from amniocentesis in order to make accurate estimates of the sex ratio at well-defined times later during pregnancy, 3) analyze ..
- RANDOMIZED TRIAL OF 11-14 WEEK AMNIOCENTESIS AND TA CVSElizabeth Thom; Fiscal Year: 1999This application accompanies a proposal entitled "Randomized Trial of 11-14 Week Amniocentesis and TA CVS" submitted by Dr. Laird Jackson leading a group of twelve clinical centers...
- Improved Classifiers for Multiplex FISHKenneth Castleman; Fiscal Year: 2004..fully and test the system in routine clinical use on prenatal, postnatal and cancer specimens from amniocentesis, peripheral blood, and bone marrow...
- SCANNING CYTOMETRY TO SORT FETAL NRBCS IN MATERNAL BLOODJeffrey Price; Fiscal Year: 2002..Genetic anomalies are to be detected by ultrasound, amniocentesis and chorionic villus sampling...
- COMPARISON OF CHORION VILLUS SAMPLING AND AMNIOCENTESISJoe Simpson; Fiscal Year: 1990..After randomization into two groups (chorionic villus sampling vs amniocentesis), we will detail medical history, prior pregnancies, genetic history and socioeconomic factors (Forms B,C,D)...
- EVALUATING A DECISION TOOL FOR PRENATAL TESTINGMiriam Kuppermann; Fiscal Year: 2002..testing for fetal chromosomal abnormalities, including maternal serum screening, chorionic villus sampling, amniocentesis, ultrasonography and no testing...
- COMPARISON OF CHORION VILLUS SAMPLING AND AMNIOCENTESISMaurice Mahoney; Fiscal Year: 1990..20 per month for 2-1/2 years who will accept randomization of their diagnostic procedure between CVB and amniocentesis. These women, through the cooperation of their obstetricians, will be identified by the eighth week of ..
- ISOLATION OF HUMAN FETAL CELLS FROM MATERNAL BLOODJames Leary; Fiscal Year: 1992..Such cells could be obtained as early as the first 8-10 weeks of pregnancy and, unlike chorion villus and amniocentesis assays, represents no risk to either mother or fetus...
- Development PsychopharmacologyDONALD NEWPORT; Fiscal Year: 2005..milk and serum of nursing infants, and prenatal exposure via collection of amniotic fluid in the event of amniocentesis. Pediatric records will be obtained annually to monitor child developmental milestones...
- COMPARISON OF CHORION VILLUS SAMPLING AND AMNIOCENTESISMITCHELL GOLBUS; Fiscal Year: 1990..Detection of genetic defects by amniocentesis has made significant contributions to medical genetics, but chorionic villus biopsy may offer access to ..
- RECOVERY OF FETAL CELLS IN MATERNAL BLOODDAVID SAMMONS; Fiscal Year: 1999..pregnancy can be recovered by charge flow separation (CFS), a method that obviates the risks associated with amniocentesis and chorionic villus sampling...
- PRENATAL INFECTION, BRAIN DEVELOPMENT AND SCHIZOPHRENIAJohn Gilmore; Fiscal Year: 2003..A clinical study of amniotic fluid obtained at amniocentesis from human pregnancies with and without prior exposure to infection will be used to determine cytokine and ..
- PRENATAL DIAGNOSIS TRIALS--FETAL CELLS/MATERNAL BLOODLee Shulman; Fiscal Year: 2000..The results of these peripheral blood studies will be compared to those that will be obtained from amniocentesis or chorionic villus sampling (CVS) on the same women...
- PRENATAL DIAGNOSIS TRIALS--FETAL CELLS/MATERNAL BLOODDIANA BIANCHI; Fiscal Year: 2000..The results of these peripheral blood studies will be compared to those that will be obtained from amniocentesis or chorionic villus sampling (CVS) on the same women...
- PRENATAL DIAGNOSIS TRIALS--FETAL CELLS/MATERNAL BLOODMark Evans; Fiscal Year: 2000..The results of these peripheral blood studies will be compared to those that will be obtained from amniocentesis or chorionic villus sampling (CVS) on the same women...
- PRENATAL DIAGNOSIS TRIALS--FETAL CELLS/MATERNAL BLOODLaird Jackson; Fiscal Year: 2000
- COMPARISON OF CHORION VILLUS SAMPLING AND AMNIOCENTESISLaird Jackson; Fiscal Year: 1990..undergoing amniocentesis at 16 weeks...
- MULTI-MEDIA TRAINING IN CYTOTECHNOLOGYBruce Cameron; Fiscal Year: 1993..in identification of the most commonly occurring cytogenetic abnormalities in metaphase cells obtained by amniocentesis or chorionic villus sampling...
- Diagnostic proteomic profiles for aneuploidyAshok Reddy; Fiscal Year: 2004..aneuploidies follows a two-step process: maternal screening and, if the results are positive, maternal amniocentesis with fetal karotyping. There are significant limitations to both first- and second-semester screening tests...
- Diagnostic proteomic profiles for aneuploidySrinivasa Nagalla; Fiscal Year: 2006..DS) currently involves suggestive serum tests that are subsequently validated by invasive procedures such as amniocentesis or chorionic villus sampling...
- ULTRASONIC EVALUATION OF FETAL LUNG MATURITYPAUL CARSON; Fiscal Year: 1990..dates of maturation or potential to respond to glucocorticoid treatment is quite limited and the necessary amniocentesis is an invasive procedure...
- HIV TRANSMISSION IN NEWBORNS: STUDY IN PREGNANTDonald Craven; Fiscal Year: 1991..fluid will also be cultured and examined for HIV antigen in women who are having a clinically indicated amniocentesis, a caesarian section, or who have not ruptured the amniotic membranes prior to delivery...
- Comprehensive non-invasive prenatal diagnosticsEugene Pergament; Fiscal Year: 2004..g., amniocentesis, chroionic villus sampling) may become a new standard of care...
- Differential Gene expression in Down Syndrome PlacentaeSusan Gross; Fiscal Year: 2003..Thus, when patients are screen positive, they are offered amniocentesis to confirm the suspicion of fetal DS...
- Exploiting a Cytochemical AND Gate in HematologyAlex Saunders; Fiscal Year: 2002..A decrease in amniocentesis means a potential savings of $1.61313 to the US health care system.
- An Interactive Informed Consent and Education Program for Pregnant WomenRobert Levine; Fiscal Year: 2009..In Phase I, we will prototype an interactive informed consent/patient education program for amniocentesis. We have teamed with Northwestern University to develop and evaluate this program and establish proof of ..
- Mechanisms of myometrial healing and regenerationCatalin Buhimschi; Fiscal Year: 2006....
- GENETIC COUNSELING STRATEGIES WITH MEXICAN-ORIGIN WOMENCarole Browner; Fiscal Year: 2002..abstract_text> ..
- Use of Genetics in Neurologists' Clinical PracticesCarole Browner; Fiscal Year: 2006..abstract_text> ..
- ALLOIMMUNIZATION TO PATERNAL LEUKOCYTES FOR HDNKenneth Moise; Fiscal Year: 2002..A monocyte monolayer assay will be performed using the spleens and sensitized red cells of the pups from the three serial breedings to determine the level of phagocytosis of the fetal reticuloendothelial system. ..
- Expanded Prenatal Testing Options and Informed ChoiceMiriam Kuppermann; Fiscal Year: 2010..In short, this study will generate a useful decision-assisting tool and provide information for use in designing cost-effective testing programs that allow for variation in preferences. ..
- Intermediate Outcomes of Hysterectomy and AlternativesMiriam Kuppermann; Fiscal Year: 2006..abstract_text> ..
- DNA Patent Policies at Academic InstitutionsLeRoy Walters; Fiscal Year: 2003..S. and Canadian academic institutions. ..
- Testing Pharmacological Therapies for Pregnant SmokersKathryn Pollak; Fiscal Year: 2006..Moreover, the study results have immediate potential to inform clinical recommendations for integrating nicotine replacement into prenatal care. ..
- Outcomes in congenital toxoplasmic retinochoroiditisRuth Gilbert; Fiscal Year: 2005..abstract_text> ..
- Thyroid Hormone Receptor Isoforms & Coactivators In VivoRoy Weiss; Fiscal Year: 2005..Such information would generate important leads in understanding the specific mechanistic aspects of TH action. ..
- Clinical Phenotype of Imprinted Genes of Chromosome 14Vernon Sutton; Fiscal Year: 2005..This phenotype delineation will lay the foundation for understanding the effects and pathogenesis of imprinted genes on chromosome 14. ..
- Advanced Reproductive Age and Environmental HealthStephanie Engel; Fiscal Year: 2007..Women with the indication of AMA, who are referred to Mount Sinai Medical Center for a routine screening amniocentesis, will be recruited...
- COOPERATIVE MULTI CENTER REPRODUCTIVE MEDICINE NETWORKEvan Myers; Fiscal Year: 2005..abstract_text> ..
- PROGRAM PROJECT GRANTJouni Uitto; Fiscal Year: 2006..abstract_text> ..
- Nuclear cofactors in Human Thyroid DiseaseRoy Weiss; Fiscal Year: 2007..3) Determine the cause for hypersensitivity to TH. This will allow clinicians to better identify factors influencing thyroid function. ..