Summary: Surgical formation of an opening into the trachea through the neck, or the opening so created.
Publications356 found, 100 shown here
- Endobrochial blockade through a tracheostomy tube for lung isolationGeorge Vretzakis
Department of Anesthesiology, University Hospital of Larissa, Greece
Anesth Analg 107:1644-5. 2008We present an alternative technique for one-lung ventilation as safe way of treating patients with tracheostomy using a fiberoptic bronchoscope and a Fogarty catheter.
- Ultrasound-guided percutaneous dilatational tracheostomy: a safe method to avoid cranial misplacement of the tracheostomy tubeA Sustic
Department of Anaesthesiology and ICU, University Hospital Rijeka, Croatia
Intensive Care Med 26:1379-81. 2000..The aim of this investigation was to evaluate the role of ultrasonography in avoiding cranial misplacement of the tracheostomy tube and tracheal ring fractures during percutaneous dilatational tracheostomy (PDT)...
- Percutaneous tracheostomy: ciaglia blue rhino versus the basic ciaglia technique of percutaneous dilational tracheostomyC Byhahn
Department of Anesthesiology, Intensive Care Medicine and Pain Control, J W Goethe University Hospital, Frankfurt, Germany
Anesth Analg 91:882-6. 2000Percutaneous dilational tracheostomy (PDT), according to Ciaglia's technique described in 1985, has become the most popular technique for percutaneous tracheostomy and is demonstrably as safe as surgical tracheostomy...
- Effect of early vs late tracheostomy placement on survival in patients receiving mechanical ventilation: the TracMan randomized trialDuncan Young
Adult Intensive Care Unit, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, England
JAMA 309:2121-9. 2013b>Tracheostomy is a widely used intervention in adult critical care units. There is little evidence to guide clinicians regarding the optimal timing for this procedure.
- [Analysis of early tracheostomy and its impact on development of pneumonia, use of resources and mortality in neurocritically ill patients]F Gandía-Martínez
Servicio de Medicina Intensiva, Hospital Clinico Universitario de Valladolid
Neurocirugia (Astur) 21:211-21. 2010We analyze the most suitable time to perform tracheostomy in neurocritically ill patients...
- Mandibular distraction in neonates: a strategy to avoid tracheostomyArlen Denny
Medical College of Wisconsin, 9000 West Wisconsin Avenue, Milwaukee, WI 53226, USA
Plast Reconstr Surg 109:896-904; discussion 905-6. 2002..past 5 years, the authors developed an application of mandibular distraction osteogenesis to eliminate existing tracheostomy. That experience led the authors to attempt mandibular distraction osteogenesis in neonates as an alternative ..
- A new simple method for percutaneous tracheostomy: controlled rotating dilation. A preliminary reportG Frova
Department of Anaesthesia and Intensive Care, Spedali Civili Brescia, Brescia, Italy
Intensive Care Med 28:299-303. 2002To describe and introduce a new technique for percutaneous dilational tracheostomy.
- Cricoid palpability as a selection criterion for bedside tracheostomyOmar F Husein
Department of Otolaryngology, The Ohio State University, Columbus, OH, USA
Otolaryngol Head Neck Surg 133:839-44. 2005To prospectively evaluate the significance of cricoid cartilage palpability as a selection criterion for bedside tracheostomy and to prospectively compare a cohort of patients undergoing bedside tracheostomy with another cohort receiving ..
- The incidence of tracheoarterial fistula in patients with chronic tracheostomy tubes: a retrospective study of 544 patients in a long-term care facilityPaul Scalise
Department of Pulmonary Medicine, Hospital for Special Care, 2150 Corbin Ave, New Britain, CT 06053, USA
Chest 128:3906-9. 2005The incidence of tracheoarterial fistula (TAF) in patients with short-term tracheostomy tubes has been reported between 0.6% and 0.7%...
- Indications, timing, and techniques of tracheostomy in 152 French ICUsFrançois Blot
Service de Reanimation Polyvalente, Institut Gustave Roussy, 39 rue Camille Desmoulins, 94805 Villejuif Cedex, France
Chest 127:1347-52. 2005To investigate the current practice of tracheostomy in French ICUs, focusing on the frequency, timing, indications, and techniques.
- Fiberoptic bronchoscopy-assisted percutaneous tracheostomy is safe in obese critically ill patients: a prospective and comparative studyCarlos M Romero
Critical Care Unit, University of Chile Clinical Hospital, Santiago Norte, Chile
J Crit Care 24:494-500. 2009..In Latin America, 10% to 35% of the population is obese. Obese critically ill patients are at greater risk for requiring intubation and prolonged mechanical ventilation; and in some cases, it is necessary to perform a tracheostomy.
- [Difficult airway management during emergency tracheostomy in a patient with severe rheumatoid arthritis]Noriko Yonemoto
Department of Anesthesia, Bellland General Hospital, Sakai 599 8247
Masui 54:39-41. 2005..Her cervical spine was ankylosed and could not be extended at all. Tracheostomy was planned under local anesthesia because of difficulty of endotracheal intubation, possibility of airway ..
- Should tracheostomy be performed as early as 72 hours in patients requiring prolonged mechanical ventilation?Charles G Durbin
Department of Anesthesiology, University of Virginia Health Science Center, Charlottesville, Virginia 22908 0170, USA
Respir Care 55:76-87. 2010..If intubation is projected to be longer than several weeks, tracheostomy is often recommended...
- Early and late outcome after single step dilatational tracheostomy versus the guide wire dilating forceps technique: a prospective randomized clinical trialBernard G Fikkers
Department of Intensive Care Medicine, Radboud University Nijmegen Medical Centre, P O Box 9600, 6500 HB, Nijmegen, The Netherlands
Intensive Care Med 37:1103-9. 2011Percutaneous tracheostomy is frequently performed in long-term ventilated patients in the intensive care unit (ICU)...
- MDCT of the central airways: comparison with bronchoscopy in the evaluation of complications of endotracheal and tracheostomy tubesMaryellen Sun
Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02115, USA
J Thorac Imaging 22:136-42. 2007To evaluate the accuracy of multidetector row computed tomography (MDCT) compared with bronchoscopy in the assessment of airway complications related to endotracheal and tracheostomy tubes.
- Utilization of tracheostomy in craniomaxillofacial trauma at a level-1 trauma centerEric P Holmgren
Department of Oral and Maxillofacial Surgery, Oregon Health and Science University, Portland, OR, USA
J Oral Maxillofac Surg 65:2005-10. 2007The decision to perform a tracheostomy on patients with maxillofacial trauma is complex. There is little data exploring the role of tracheostomy in facial fracture management...
- Timing of tracheostomy as a determinant of weaning success in critically ill patients: a retrospective studyChia Lin Hsu
Division of Pulmonary Medicine, Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan
Crit Care 9:R46-52. 2005b>Tracheostomy is frequently performed in critically ill patients for prolonged intubation...
- The effect of tracheostomy timing during critical illness on long-term survivalDamon C Scales
Department of Critical Care, Sunnybrook Health Sciences Centre, University of Toronto, ON, Canada
Crit Care Med 36:2547-57. 2008b>Tracheostomy is common in intensive care unit patients, but the appropriate timing is controversial.
- Bedside ultrasound screening for pretracheal vascular structures may minimize the risks of percutaneous dilatational tracheostomyAlexander C Flint
Neurocritical Care and Pulmonary Critical Care, Head and Neck Surgery, Kaiser Permanente, 1150 Veterans Blvd, Redwood City, CA 94063, USA
Neurocrit Care 11:372-6. 2009Percutaneous dilatational tracheostomy (PDT) continues to gain in popularity as a bedside method for tracheostomy placement in the intensive care unit...
- Tracheotomy: clinical review and guidelinesPaul De Leyn
Department of Thoracic Surgery, University Hospital Leuven, Belgium
Eur J Cardiothorac Surg 32:412-21. 2007..PDT should be considered the procedure of choice in elective non-urgent tracheotomy. There are some relative contraindications for PDT, but with growing experience, they become less frequent...
- A prospective, randomized study comparing percutaneous with surgical tracheostomy in critically ill patientsB D Freeman
Department of Surgery, Washington University School of Medicine, St. Louis, MO, USA
Crit Care Med 29:926-30. 2001OBJECTIVE: To determine the relative cost-effectiveness of percutaneous dilational tracheostomy (PDT) and surgical tracheostomy (ST) in critically ill patients. DESIGN: Prospective randomized study...
- Tracheo-innominate artery fistula after percutaneous tracheostomy: three case reports and a clinical reviewC A Grant
Critical Care Unit, University Hospital, Aintree, Liverpool, UK
Br J Anaesth 96:127-31. 2006Tracheo-innominate artery fistula (TIF) is an uncommon yet life threatening complication after a tracheostomy. Rates of 0.1-1% after surgical tracheostomy have been reported, with a peak incidence at 7-14 days post procedure...
- Tracheostomy in patients with long-term mechanical ventilation: a surveySantino Marchese
Respiratory Intensive Care Unit, Terapia Intensiva Respiratoria, Ospedale Civico, ARNAS, Via C Lazzaro, Palermo, Italy
Respir Med 104:749-53. 2010b>Tracheostomy is increasingly performed in intensive care units (ICU), with many patients transferred to respiratory ICU (RICU). Indications/timing for closing tracheostomy are discussed.
- Neurologic examination and extubation outcome in the neurocritical care unitChristopher D Anderson
Neurocritical Care Service, Massachusetts General Hospital, 55 Fruit Street, Boston, MA 02114, USA
Neurocrit Care 15:490-7. 2011..Extubation failure in the neurocritical care unit (NCCU) is difficult to predict, and is an important source of prolonged intensive care, exposure to morbidity, and increased cost...
- Tracheostomy decannulation failure rate following critical illness: a prospective descriptive studyKim Choate
The Alfred, Commercial Road, Prahran, Victoria 3181, Australia
Aust Crit Care 22:8-15. 2009b>Tracheostomy is a well established and practical approach to airway management for patients requiring extended periods of mechanical ventilation or airway protection...
- Early tracheostomy decreases ventilation time but has no impact on mortality of intensive care patients: a randomized studyTillo Koch
Department of Anaesthesiology and Intensive Care Medicine, University Hospital of Gießen, Rudolf Buchheim Straße 7, Giesen, Germany
Langenbecks Arch Surg 397:1001-8. 2012..While the influence of tracheostomy on VAP incidence, duration of ventilation, and time of hospitalization has already been analyzed in several ..
- Percutaneous dilational tracheostomy: an initial experience in community based teaching hospitalS Joshi
Department of Anaesthesiology and Critical Care, B P Koirala Institute of Health Sciences, Dharan, Nepal
Kathmandu Univ Med J (KUMJ) 4:275-80. 2006Percutaneous dilational tracheostomy (PDT) is frequently performed in the intensive care unit to prevent the long term complications associated with prolonged endotracheal intubation.
- Tracheostomy in critically ill patientsAbhiram Mallick
Leeds General Infirmary, Leeds, UK
Eur J Anaesthesiol 27:676-82. 2010b>Tracheostomy is performed in about a quarter of ICU patients requiring prolonged mechanical ventilation, weaning from assisted ventilation, airway suction and airway protection...
- Amelioration of pathological yawning after tracheostomy in a patient with locked-in syndromeC C Chang
Eur J Neurol 15:e66-7. 2008
- Tracheostomy decannulation: implication on respiratory mechanicsDominic Dellweg
Fachkrankenhaus Kloster Grafschaft, Annostr 1, 57392 Schmallenberg, Germany
Head Neck 29:1121-7. 2007b>Tracheostomy decreases airway resistance and work of breathing. No comprehensive data are available on respiratory mechanics after tracheostomy decannulation. We evaluated respiratory mechanics after decannulation.
- Decannulation following tracheostomy for prolonged mechanical ventilationHeidi H O'Connor
Pulmonary and Sleep Division, New England Sinai Hospital, Stoughton, MA 02072, USA
J Intensive Care Med 24:187-94. 2009We examined the process of decannulation following tracheostomy in patients transferred to a long-term acute care (LTAC) hospital for weaning from prolonged mechanical ventilation (PMV).
- An intensivist-led tracheostomy review team is associated with shorter decannulation time and length of stay: a prospective cohort studyAntony E Tobin
Intensive Care Unit, St, Vincent s Hospital Melbourne, PO Box 2900, Fitzroy VIC 3065, Australia
Crit Care 12:R48. 2008Without specific strategies to address tracheostomy care on the wards, patients discharged from the intensive care unit (ICU) with a tracheostomy may receive suboptimal care...
- Predictors of successful decannulation using a tracheostomy retainer in patients with prolonged weaning and persisting respiratory failureStephan Budweiser
Division of Pulmonary and Respiratory Medicine, Department of Internal Medicine III, RoMed Clinical Center Rosenheim, Rosenheim, Germany
Respiration 84:469-76. 2012..For percutaneously tracheostomized patients with prolonged weaning and persisting respiratory failure, the adequate time point for safe decannulation and switch to noninvasive ventilation is an important clinical issue...
- The long-term evaluation of tracheostomy in the management of severe obstructive sleep apneaGentry W Thatcher
Department of Otolaryngology, Hennepin County Medical Center and the University of Minnesota, Minneapolis, Minnesota 55415, USA
Laryngoscope 113:201-4. 2003..To determine the long-term success and morbidity of tracheostomies for patients with severe obstructive sleep apnea...
- A North American survey of respiratory therapist and physician tracheostomy decannulation practicesHenry Thomas Stelfox
Department of Critical Care Medicine, University of Calgary, Foothills Medical Centre EG23A, 1403 29 Street NW, Calgary, Alberta T2N 2T9 Canada
Respir Care 54:1658-64. 2009b>Tracheostomy is a common surgical procedure performed on critically ill patients...
- Decannulation and survival following tracheostomy in an intensive care unitRandal Leung
Department of Head and Neck Surgery and Otolaryngology, Royal Melbourne Hospital, Parkville, Australia
Ann Otol Rhinol Laryngol 112:853-8. 2003We investigated the long-term outcome of patients requiring tracheostomy in an intensive care unit (ICU) in an attempt to identify risk factors that would indicate a low probability of early decannulation...
- Determinants of tracheostomy decannulation: an international surveyHenry Thomas Stelfox
Department of Critical Care Medicine, University of Calgary, Foothills Medical Centre, EG23A, 1403 29 Street NW, Calgary, AB, Canada, T2N 2T9
Crit Care 12:R26. 2008Although tracheostomy is probably the most common surgical procedure performed on critically ill patients, it is unknown when a tracheostomy tube can be safely removed.
- [Mechanical ventilation of weaning interruption]Rosane Goldwasser
J Bras Pneumol 33:S128-36. 2007
- Survey of use of the insufflator-exsufflator in patients with spinal cord injuryJames K Schmitt
Department of Internal Medicine, H H McGuire VA Medical Center, 1201 Broad Rock Boulevard, Richmond, VA 23113, USA
J Spinal Cord Med 30:127-30. 2007..However, many institutions do not use this device. The study was performed to assess use of the device and attitudes among health care providers...
- Rapid reduction of antihypertensive medications and insulin requirements after tracheostomy in a patient with severe obstructive sleep apnea syndromeArvind Bhimaraj
Department of Medicine, Drexel University College of Medicine, Philadelphia, PA, USA
J Clin Sleep Med 3:297-9. 2007..sleep apnea syndrome, diabetes mellitus, and hypertension, with postoperative complications following tracheostomy. His stormy postoperative course is presented with emphasis on glycemic control and hypertension...
- Stroke-related Early Tracheostomy versus Prolonged Orotracheal Intubation in Neurocritical Care Trial (SETPOINT): a randomized pilot trialJulian Bösel
Department of Neurology, University of Heidelberg, Im Neuenheimer Feld 400, Heidelberg D 69121, Germany
Stroke 44:21-8. 2013Optimal timing of tracheostomy in ventilated patients with severe stroke is unclear. We aimed to investigate feasibility, safety, and potential advantages of early tracheostomy in these intensive care unit (ICU) patients.
- Incidence and clinical predictors for tracheostomy after cervical spinal cord injury: a National Trauma Databank reviewBernardino C Branco
Division of Trauma and Surgical Critical Care, University of Southern California, Los Angeles, California 90033, USA
J Trauma 70:111-5. 2011The purpose of this study was to determine the incidence and identify clinical predictors for the need for tracheostomy after cervical spinal cord injury (CSCI).
- The use of cognitive task analysis to improve the learning of percutaneous tracheostomy placementMaura E Sullivan
Department of Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
Am J Surg 193:96-9. 2007The purpose of the current study was to determine the effectiveness of using cognitive task analysis (CTA) to develop a curriculum to teach the behavioral skills and the cognitive strategies of a percutaneous tracheostomy (PT) placement.
- Tracheostomy as treatment for adult obstructive sleep apnea: a systematic review and meta-analysisMacario Camacho
Department of Otolaryngology Head and Neck Surgery, Sleep Surgery Division, Stanford University Medical Center, Stanford, California, U S A
Laryngoscope 124:803-11. 2014To systematically review outcomes for polysomnography, sleepiness, and mortality in patients who undergo tracheostomy for the treatment of adult obstructive sleep apnea (OSA).
- Definitive establishment of airway control is critical for optimal outcome in lower cervical spinal cord injuryVictor J Hassid
Department of Surgery, University of Florida Health Science Center, Jacksonville, Florida 32209, USA
J Trauma 65:1328-32. 2008..This study sought to determine the incidence and effect of catastrophic airway loss (CLA) and to define the need for elective intubation with subsequent tracheostomy to prevent potentially fatal outcomes.
- Early versus late percutaneous dilational tracheostomy in critically ill patients anticipated requiring prolonged mechanical ventilationYue Zheng
Department of Surgical Intensive Care Unit, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China
Chin Med J (Engl) 125:1925-30. 2012b>Tracheostomy should be considered to replace endotracheal intubation in patients requiring prolonged mechanical ventilation (MV). However, the optimal timing for tracheostomy is still a topic of debate...
- Performance of the coughassist insufflation-exsufflation device in the presence of an endotracheal tube or tracheostomy tube: a bench studyClaude Guerin
Service de Réanimation Médicale et d Assistance Respiratoire, Hopital de la Croix Rousse, Lyon, France
Respir Care 56:1108-14. 2011..The device may benefit intubated and tracheotomized patients. We assessed the impact of various artificial airways on peak expiratory flow (PEF) with the CoughAssist...
- Tracheostomy after anterior cervical spine fixationTerence O'Keeffe
Department of Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
J Trauma 57:855-60. 2004Patients with cervical spine injury may require both anterior cervical spine fusion and tracheostomy, particularly in the setting of associated cervical spinal cord injury (SCI)...
- The influence of long-term tracheostomy on speech and language development in childrenD Jiang
Department of Otolaryngology, Head and Neck Surgery, Guy s Hospital, London, UK
Int J Pediatr Otorhinolaryngol 67:S217-20. 2003..With no coexisting neurological impairment, some suggested that tracheostomy has little influence on speech development, whilst others showed a clear pattern of language disability...
- Diaphragmatic rupture due to violent cough during tracheostomyHiroshi Nakanishi
Department of Otolaryngology, Hamamatsu University School of Medicine, Handayama, and Hamamatsu Red Cross Hospital, Hamamatsu, Japan
Auris Nasus Larynx 37:121-4. 2010We present herein a rare case of diaphragmatic rupture due to violent coughing during tracheostomy. A 73-year-old man was admitted with cough, hoarseness and dysphagia caused by a huge laryngeal cancer obstructing the airways...
- Early tracheostomy does not improve outcome in burn patientsJeffrey R Saffle
Department of Surgery and the Intermountain Burn Center, University of Utah Health Center, Salt Lake City, Utah 84132, USA
J Burn Care Rehabil 23:431-8. 2002Early tracheostomy (ET) has been claimed to reduce ventilator support or intensive care unit or hospital length of stay in intensive care unit patients. This study was performed to assess the potential benefits of ET in burn patients...
- Bench-to-bedside review: early tracheostomy in critically ill trauma patientsNehad Shirawi
Intensive Care Department, King Abdulaziz Medical City, Riyadh, Kingdom of Saudi Arabia
Crit Care 10:201. 2006A significant proportion of trauma patients require tracheostomy during intensive care unit stay. The timing of this procedure remains a subject of debate...
- Characterizing the need for tracheostomy placement and decannulation after cervical spinal cord injuryHiroaki Nakashima
Department of Orthopaedic Surgery, Nagoya University Hospital, Graduate School of Medicine, 65 Tsurumai, Shouwa ku, Nagoya, Aichi 466 8560, Japan
Eur Spine J 22:1526-32. 2013There have been few reports on the risk factors for tracheostomy and the possibility of patients for decannulation...
- Long-term azithromycin use in patients with chronic obstructive pulmonary disease and tracheostomyFrancesco Blasi
Dipartimento Toraco polmonare e Cardio circolatorio, University of Milan, IRCCS Fondazione Po Ma Re, Milan, Italy
Pulm Pharmacol Ther 23:200-7. 2010Patients with Chronic Obstructive Pulmonary Disease (COPD) and tracheostomy are at high risk for exacerbations and hospitalizations. Macrolide treatment has shown to reduce exacerbations in moderate-to-severe COPD...
- Closure of laryngotracheal cavity and tracheostomy for intractable aspiration secondary to radiation encephalopathy or radiation damage of cranial nerve after radiotherapy of nasopharyngeal carcinomaShenhong Qu
Hospital of Otorhinolaryngology, First Affiliated Hospital of Sun Yat sen University, Guangzhou, People s Republic of China
Acta Otolaryngol 126:962-6. 2006Closure of the laryngotracheal cavity and tracheostomy is especially suitable for intractable aspiration secondary to radiation encephalopathy or damage of cranial nerve after radiation for nasopharyngeal carcinoma (NPC).
- Physiological responses during a T-piece weaning trial with a deflated tubePiero Ceriana
Respiratory Intensive Care Unit, Fondazione S Maugeri, IRCCS, Istituto Scientifico di Pavia, Via Ferrata 8, 27100 Pavia, Italy
Intensive Care Med 32:1399-403. 2006T-piece trials and spontaneous breathing trials through the tracheostomy tube are often used as weaning techniques...
- Timing of tracheostomy after anterior cervical spine fixationRanjith Babu
Division of Neurosurgery, Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
J Trauma Acute Care Surg 74:961-6. 2013Patients with cervical spinal cord injury frequently undergo early anterior cervical spine fixation (ACSF) and tracheostomy procedures to reduce further deterioration, to reduce risk of pulmonary complications, and to improve patient ..
- The effects of increasing effective airway diameter on weaning from mechanical ventilation in tracheostomized patients: a randomized controlled trialGonzalo Hernandez
Intensive Care Unit, Hospital Infanta Sofia, Madrid, Spain
Intensive Care Med 39:1063-70. 2013..To determine the effects of deflating the tracheal cuff during disconnections from mechanical ventilation (MV) in tracheostomized patients...
- The impact of tracheostomy timing in patients with severe head injury: an observational cohort studyHao Kuang Wang
Department of Neurosurgery, E Da Hospital, I Shou University, Kaohsiung, Taiwan
Injury 43:1432-6. 2012A retrospective analysis of 66 adults with severe head injury admitted to the neurosurgical intensive care unit (ICU) who required tracheostomy.
- Role of anaerobic bacteria in infections following tracheostomy, intubation, or the use of ventilatory tubes in childrenItzhak Brook
Department of Pediatrics, Georgetown University School of Medicine, Washington, DC, USA
Ann Otol Rhinol Laryngol 113:830-4. 2004Colonization of the tracheobronchial tree with microorganisms almost always follows tracheal intubation, tracheostomy, or the use of ventilatory tubes...
- Results of endoscopic tracheoplasty for treating tracheostomy-related airway stenosisS A R Nouraei
Clin Otolaryngol 32:471-5. 2007Post-tracheostomy 'lambdoid' deformity of the trachea is a specific and uncommon variant of adult post-intubation laryngotracheal stenosis, in which airway obstruction is caused by inward collapse of over-resected tracheal cartilage as a ..
- Study of the effectiveness of bronchial clearance in subjects with upper spinal cord injuries: examination of a rehabilitation programme involving mechanical insufflation and exsufflationP Pillastrini
Department of Neurological Sciences, Rehabilitative Sciences S S D MED 48, University of Bologna, Bologna, Italy
Spinal Cord 44:614-6. 2006..Randomized controlled trial...
- Effect of technique and timing of tracheostomy in patients with acute traumatic spinal cord injury undergoing mechanical ventilationJavier Romero Ganuza
Intensive Care Unit and Internal Medicine Department, Paraplejics National Hospital, Toledo, Spain
J Spinal Cord Med 34:76-84. 2011To assess the effect of timing and techniques of tracheostomy on morbidity, mortality, and the burden of resources in patients with acute traumatic spinal cord injuries (SCls) undergoing mechanical ventilation.
- Unaided speech in tube-free tracheostomy: The supplementary sling procedureIsaac Eliachar
Department of Otolaryngology, The Cleveland Clinic Foundation, Ohio 44195, USA
Otolaryngol Head Neck Surg 127:213-20. 2002In some patients after tube-free tracheostomy, air escape hinders voice optimization. Our objective was to determine whether a supplementary sling procedure could reduce air escape and improve unaided speech and cough in these patients.
- Does acuity matter?--Optimal timing of tracheostomy stratified by injury severityJason M Schauer
Department of Public Health Sciences, Division of Biostatistics, Penn State College of Medicine, Hershey, PA 17033, USA
J Trauma 66:220-5. 2009A number of conflicting studies have been conducted to analyze the relationship between the timing of tracheostomy and mortality, intensive care unit (ICU) length of stay (LOS), hospital LOS, and the incidence of pneumonia...
- Tracheostomy in amyotrophic lateral sclerosis: a 10-year population-based study in ItalyA Chio
ALS Centre, Department of Neuroscience, University of Torino, Torino, Italy
J Neurol Neurosurg Psychiatry 81:1141-3. 2010We evaluated the clinical characteristics and outcome of tracheostomy in amyotrophic lateral sclerosis (ALS) using data from the Piemonte and Valle d'Aosta Register for ALS, a prospective epidemiological register collecting all ALS ..
- Respiratory care of patients with cervical spinal cord injury: a reviewSumesh Arora
Prince of Wales Hospital, Sydney, NSW, Australia
Crit Care Resusc 14:64-73. 2012..Prolonged mechanical ventilation and tracheostomy are often required...
- Early tracheostomy is associated with improved outcomes in patients who require prolonged mechanical ventilation after cardiac surgeryJagan Devarajan
Department of General Anesthesia, Cleveland Clinic, Cleveland, OH 44195, USA
J Am Coll Surg 214:1008-16.e4. 2012The best time to perform a tracheostomy in cardiac surgery patients who require prolonged postoperative mechanical ventilation remains unknown...
- External control of exhalation for cough assistance: a method for patients with glottis dysfunction and/or tracheostomySang Chul Lee
Department of Physical Medicine and Rehabilitation, Myongji Hospital, Kwandong University College of Medicine, Koyang, Kyunggi, Korea
Arch Phys Med Rehabil 90:1402-7. 2009To investigate the effectiveness of our method of assisting a cough by mimicking the functions of the glottis in patients with bulbar muscle weakness or paralysis and/or those who had a tracheostomy tube.
- A permanent tube-free tracheostomy in a morbidly obese patient with severe obstructive sleep apnea syndromeRon Eliashar
Department of Otolaryngology Head and Neck Surgery, Hadassah University Hospital, Jerusalem, Israel
Isr Med Assoc J 4:1156-7. 2002
- Comparing percutaneous tracheostomy with open surgical tracheostomyIrawan Susanto
BMJ 324:3-4. 2002
- Airway fire due to diathermy during tracheostomy in an intensive care patientS A Rogers
Department of Anaesthesia and Intensive Care, The Cardiothoracic Centre, Liverpool, UK
Anaesthesia 56:441-3. 2001We describe a case of airway fire in an 83-year-old, critically ill patient. The fire occurred during a surgical tracheostomy under general anaesthesia, following ignition of the tracheal tube by diathermy...
- Montgomery T-tube placement in the treatment of benign tracheal lesionsAngelo Carretta
Department of Thoracic Surgery, Vita Salute San Raffaele University, San Raffaele Scientific Institute, Via Olgettina, 60, 20132, Milan, Italy
Eur J Cardiothorac Surg 36:352-6; discussion 356. 2009..We retrospectively investigated Montgomery T-tube placement as an alternative or complementary treatment to surgery...
- Tracheal ring fracture--dislodgement after Blue Rhino percutaneous tracheostomyA Thomas
Anaesthesia 58:1241. 2003
- Physiologic effects of open and closed tracheostomy tubes on the pharyngeal swallowRoxann Diez Gross
Department of Audiology and Speech Pathology, Veterans Administration Pittsburgh Healthcare System, Pittsburgh, Pennsylvania 15240, USA
Ann Otol Rhinol Laryngol 112:143-52. 2003Studies linking aspiration and dysphagia to an open tracheostomy tube exemplify the possibility that the larynx may have an influence on oropharyngeal swallow function...
- Early vs late tracheostomy in critical careJim Down
University College Hospital, London
Br J Hosp Med (Lond) 70:510-3. 2009This article reviews the current literature and practice of tracheostomy with consideration of timing and the benefits of early tracheostomy, taking account of the results from the recent TracMan study.
- Comparison of open versus bedside percutaneous dilatational tracheostomy in the cardiothoracic surgical patient: outcomes and financial analysisMatthew D Bacchetta
Department of Cardiothoracic Surgery, New York Presbyterian Hospital, Cornell University, New York, New York 10021, USA
Ann Thorac Surg 79:1879-85. 2005The clinical and financial outcomes of a change in practice from traditional tracheostomy (open) to bedside percutaneous dilatational tracheostomies (PDT) was evaluated in patients who underwent cardiothoracic surgery.
- Prospective randomized trial comparing the effect of early suturing of tracheostomy sites on postoperative patient swallowing and rehabilitationJames T Brookes
Division of Otolaryngology Head and Neck Surgery, University of Alberta, Edmonton, Alberta
J Otolaryngol 35:77-82. 2006This study was designed to evaluate the effect of tracheostomy site suturing after decannulation on swallowing rehabilitation, the incidence of postoperative complications, the length of hospital stay, and overall cost saving in patients ..
- Ciaglia percutaneous dilational tracheostomy. Early and late complications and follow-upG Gambale
CU 118, Emergency Department, Ospedale Maggiore, Bologna, Italy
Minerva Anestesiol 69:825-30; 830-3. 2003Evaluation of the safety of percutaneous dilational tracheostomy (PDT) for perioperative, early and late complications.
- Safety, efficiency, and cost-effectiveness of a multidisciplinary percutaneous tracheostomy programMarek A Mirski
Department of Anesthesiology and Critical Care Medicine, Johns Hopkins Medicine, Baltimore, MD, USA
Crit Care Med 40:1827-34. 2012..Prioritizing patient safety, a tracheostomy team was created at our institution to provide bedside expertise in surgery, anesthesiology, respiratory, and ..
- Assessment of ventilation during the performance of elective endoscopic-guided percutaneous tracheostomy: clinical evaluation of a new methodFausto Ferraro
Dipartimento di Scienze Anestesiologiche, Chirurgiche e dell Emergenza, Servizio di Terapia Intensiva, Seconda Universita degli Studi di Napoli, Naples, Italy
Chest 126:159-64. 2004To evaluate the feasibility of uninterrupted translaryngeal open ventilation delivered through a pediatric, uncuffed endotracheal tube during percutaneous endoscopic tracheostomy (PET).
- Submental intubation versus tracheostomy in maxillofacial trauma patientsPetr Schutz
Oral and Maxillofacial Surgery Unit, Al Adan Dental Center and the Oral and Maxillofacial Surgery Department, Ministry of Health, State of Kuwait
J Oral Maxillofac Surg 66:1404-9. 2008To evaluate the indications and outcomes of airway management by submental intubation or tracheostomy in patients with maxillofacial trauma, and to describe the technique of submental intubation in detail and discuss its latest refinements...
- Alternative to tracheostomy: submental intubation in craniomaxillofacial traumaKaren F Kim
Division of Plastic Surgery, Georgetown University Medical Center, Washington, DC 20007, USA
J Craniofac Surg 16:498-500. 2005..As described by Altemir in 1986, submental intubation is a useful technique as an alternative to tracheostomy in selected trauma patients...
- Percutaneous dilatational tracheostomy: review of technique and evidence for its useSrinivas M Susarla
Department of Surgery, Massachusetts General Hospital, Boston, MA, USA
J Oral Maxillofac Surg 70:74-82. 2012b>Tracheostomy is a technique for airway management commonly used by surgeons who care for critically ill patients...
- Tracheostomy and mechanical ventilation weaning in children affected by respiratory virus according to a weaning protocol in a pediatric intensive care unit in Argentina: an observational restrospective trialGustavo Caprotta
Head of Pediatric Intensive Care Unit of Hospital de Trauma y Emergencia Dr Federico Abete, Malvinas Argentinas Buenos Aires, Argentina
Ital J Pediatr 37:5. 2011..Although the spontaneous breathing trials were successful, the patients failed all extubations. Therefore a tracheostomy was performed and the weaning plan was begun...
- Modified technique of percutaneous dilational tracheostomy in 600 casesGeogios Leptidis
Emergency Department, General Hospital of Nikea Piraeus, D Mantouvalou 3, Nikea 18454, Greece
World J Surg 26:1214-6. 2002b>Tracheostomy is frequently required for the treatment of critically ill patients to prevent the complications with prolonged translaryngeal intubation...
- Preventing bleeding complications in percutaneous tracheostomy--another role for portable ultrasound in intensive careD King
Br J Anaesth 91:607; author reply 607-8. 2003
- Translaryngeal tracheostomy: experience of 340 casesMichael D Sharpe
Department of Anesthesia, London Health Sciences Centre University Campus, 339 Windermere Road, London, Ontario, Canada N6A 5A5
Laryngoscope 113:530-6. 2003To describe the authors' initial experience with a new and innovative dilational translaryngeal tracheostomy bedside technique.
- Dilatative percutaneous tracheostomy during double antiplatelet therapy: two consecutive casesL Cabrini
Department of Intensive Care, San Raffaele Hospital and Vita Salute University of Milan, Milan, Italy
Minerva Anestesiol 74:565-7. 2008This article reports two cases of dilatative percutaneous tracheostomy performed on patients treated with double antiplatelet therapy. Both patients had cardiac arrest following myocardial infarction...
- Facilitating speech in the patient with a tracheostomyDean R Hess
Department of Respiratory Care, Ellison 401, Massachusetts General Hospital, 55 Fruit Street, Boston MA 02114, USA
Respir Care 50:519-25. 2005A tracheostomy tube decreases the ability of the patient to communicate effectively. The ability to speak provides an important improvement in the quality of life for a patient with a tracheostomy...
- Percutaneous dilational tracheostomy kit: an aid to submental intubationBinay Kumar Biswas
Anesth Analg 103:1055. 2006
- [PercuTwist dilational tracheostomy. Prospective evaluation of 54 consecutive patients]M Grundling
Klinik und Poliklinik für Anästhesiologie und Intensivmedizin, Klinikum der Ernst Moritz Arndt Universität Greifswald
Anaesthesist 53:434-40. 2004Percutaneous dilational tracheostomy (PDT) is considered to be an accepted method in intensive care patients. In 2002 Frova and Quintel described a method of dilation that employed controlled rotation of the PercuTwist dilational device...
- Percutaneous tracheostomy tube obstruction: warningSteven J Trottier
Department of Critical Care Medicine, St John s Mercy Medical Center, St Louis University, Tower B 4006, 621 South New Ballas Road, St Louis, MO 63141, USA
Chest 122:1377-81. 2002To determine the patency of standard and modified Portex tracheostomy tubes inserted by the percutaneous dilatational technique.
- Tracheostomy tube ignition during microlaryngeal surgery using diode laser: a case reportHsun Mo Wang
Department of Otolaryngology, Kaohsiung Medical University Chung Ho Memorial Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
Kaohsiung J Med Sci 22:199-202. 2006..using a diode laser under general anesthesia via 60% FiO2, with an airway fire occurring at the tracheostomy tube and causing tubal damage and obstruction...
- The impact of time to tracheostomy on mechanical ventilation duration, length of stay, and mortality in intensive care unit patientsYaseen M Arabi
Department of Intensive Care, King Abdulaziz Medical City, Riyadh, Saudi Arabia
J Crit Care 24:435-40. 2009This study examined the potential effects of time to tracheostomy on mechanical ventilation duration, intensive care unit (ICU), and hospital length of stay (LOS), and ICU and hospital mortality.
- Tracheostomy protocol compliance: herding cats?Linda Liu
Crit Care Med 36:1959-60. 2008
- Impact of early vs. late tracheostomy on weaning: a retrospective analysisJ Bickenbach
Department of Intensive Care, University Hospital Aachen, RWTH Aachen University, Aachen, Germany
Minerva Anestesiol 77:1176-83. 2011Early tracheostomy has been advocated for a number of reasons. Especially in association with weaning from mechanical ventilation, it is known that an early timepoint can help patients being weaned more rapidly from the ventilator...
- Tracheostomy: current practice on timing, correction of coagulation disorders and peri-operative management - a postal survey in the NetherlandsD P Veelo
Department of Intensive Care Medicine, Academic Medical Center, University of Amsterdam, Amsterdam
Acta Anaesthesiol Scand 51:1231-6. 2007Several factors may delay tracheostomy. As many critically ill patients either suffer from coagulation abnormalities or are being treated with anticoagulants, fear of bleeding complications during the procedure may also delay tracheostomy...
- Flooding with carbon dioxide prevents airway fire induced by diathermy during open tracheostomyAnthony M H Ho
Department of Anaesthesia and Intensive Care, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, SAR
J Trauma 63:228-31. 2007Open tracheostomy is commonly performed during head and neck surgery, and in critically ill patients. Diathermy-induced airway fire during tracheotomy is rare but may have grave implications...
- Sending children home on tracheostomy dependent ventilation: pitfalls and outcomesE A Edwards
Great Ormond Street Hospital for Children NHS Trust, London, UK
Arch Dis Child 89:251-5. 2004..review will enable health practitioners and local health providers to anticipate the hurdles, address the problems early, and expedite the process of discharging home children who are dependent on long term ventilation via tracheostomy.
- Percutaneous tracheostomy in patients with severe liver disease and a high incidence of refractory coagulopathy: a prospective trialGeorg Auzinger
Institute of Liver Studies, Liver Intensive Care Unit, King s College Hospital, London SE5 9RS, United Kingdom
Crit Care 11:R110. 2007To assess the safety of percutaneous dilational tracheostomy (PDT) performed by experienced operators in critically ill patients with liver disease and coagulopathy.
- Diagnosis of Subglottic Stenosis and Edema in Neonates Using OCTBrian Wong; Fiscal Year: 2013..SGS and other ICU acquired laryngeal and upper airway diseases that lead to failed extubation and ultimately tracheostomy. PUBLIC HEALTH RELEVANCE: Subglottic stenosis is the most common indication for tracheostomy in critically ill ..
- Effectiveness of ICP Monitoring in Pediatric Traumatic Brain InjuryTELLEN BENNETT; Fiscal Year: 2013..the accuracy of database codes in the linked dataset and a proxy poor functional outcome, survival with tracheostomy and gastrostomy, by conducting a three-year prospective cohort study at a single, high volume, pediatric trauma ..
- Manipulating Macrophage Phenotype in Laryngeal Nerve RepairJonathan Cheetham; Fiscal Year: 2013..Bilateral injury to the RLN can result in potentially life- threatening airway obstruction and the need for tracheostomy. The RLN can regenerate some of its axons, but more than half of patients with paralysis require some form of ..
- Phase II/III Study of Arimoclomol in the Treatment of SOD1 Positive Familial?.Merit E Cudkowicz; Fiscal Year: 2013..Secondary outcome measures include time to tracheostomy or permanent assisted ventilation, forced vital capacity, negative inspiratory force, strength, long-term ..
- Intra-pulmonary aerosol delivery for intubated pediatric patientsAMIR A NAQWI; Fiscal Year: 2013..improved method for intra-pulmonary drug delivery in pediatric patients who are intubated or have a tracheostomy. Currently available aerosolizing devices are limited in that only certain agents and only a small fraction (..
- Dysregulation of RGS2 Protein and Airway Hyperresponsiveness in AsthmaYaping Tu; Fiscal Year: 2013..We will first determine effects of RGS2 KO on house dust mite (HDM)-induced mouse AHR using invasive tracheostomy and precision-cut lung slices...
- Health-care Providers Roles in Decision Making in Pediatric Palliative CareSavithri Nageswaran; Fiscal Year: 2013..1 and 2, we will conduct in-depth, semi-structured interviews of 40 caregivers of children who have received tracheostomy or chronic mechanical ventilation...
- Improving Healthcare Integration for Children with TracheostomyJAY GRIFFIN BERRY; Fiscal Year: 2013..study the impact of an internet-based care plan application to improve healthcare integration for children with tracheostomy, and improve health outcomes for these children...
- REDUCING ENDOTRACHEAL TUBE INFECTION USING IGGJEFFREY SLUNT; Fiscal Year: 1999Endotracheal tubes are a common biomedical device in widespread use for anesthesiology and tracheostomy procedures and for long-term ventilation...
- Pulmonary Airflow Monitor in Tracheostomized ChildrenMALVERN BENJAMIN; Fiscal Year: 2003..high fidelity flow sensor to continuously monitor tracheal gas flow in infants and young children who require a tracheostomy tube for relief of airway obstruction or chronic respiratory failure...
- FUNCTION AND CONTROL OF THE LARYNX IN THE NEONATEAlastair Hutchison; Fiscal Year: 1991..Since anesthesia and the presence of a tracheostomy can profoundly affect laryngeal muscle function, we shall study the lambs unanesthetized, with intact airways...
- HIGH RESOLUTION ECHOCARDIOGRAPHY SYSTEMMichael Zile; Fiscal Year: 2001..of cardiac function in mice, investigators were limited to invasive measurements requiring heavy anesthesia, tracheostomy, and catheterization...
- Pulmonary Airflow Monitor in Tracheostomized ChildrenMALVERN BENJAMIN; Fiscal Year: 2007..life threatening emergencies, highly complex surgery, and acute respiratory failure and subsequently require a tracheostomy for months or sometimes years...
- Molecular genetics of familial laryngeal paralysisJose Manaligod; Fiscal Year: 2006Laryngeal paralysis is a frequent cause of stridor and airway obstruction in infants, often requiring tracheostomy or other surgical procedures to provide an adequate airway...
- DETERMINANTS OF CARDIAC ABNORMALITIES IN ALCOHOLICSTimothy Regan; Fiscal Year: 1980..In view of the fact that long-term tracheostomy preparations in the large mongrel dog are not feasible and since chronic nicotine administration qualitatively ..
- Modafinil Treatment for Fatigue in HIV+ PatientsJudith Rabkin; Fiscal Year: 2008..The major aims concern modafinil efficacy for fatigue compared to placebo, safety in terms of effects on immunologic/virologic measures, and impact on depressive symptoms when present at baseline. ..
- DHEA EFFECTS ON MOOD IN DEPRESSED HIV+ PATIENTSJudith Rabkin; Fiscal Year: 2003..This will permit the investigators to assess potential underlying mechanisms for the putative therapeutic effects of DHEA on mood, libido, and body composition. ..
- DYING AT HOME OF AIDS & CANCER: PREFERENCES & OUTCOMESJudith Rabkin; Fiscal Year: 2004..The data collected in the preliminary study will be used in the full-scale study. ..
- PHARMACOGENETICS IN SURGICAL CRITICAL CAREBradley Freeman; Fiscal Year: 2004..The environment for this project is Washington University School of Medicine, an institution with access to a large clinical volume and established expertise in genomic research. ..
- Outcomes of Prolonged Mechanical VentilationShannon Carson; Fiscal Year: 2006..In addition, these data will inform future cohort studies and randomized controlled trials designed to improve outcomes for this growing patient population. ..
- Metabolomic Signatures in ALSMerit Cudkowicz; Fiscal Year: 2005..abstract_text> ..
- Speech Intelligibility Testing in Children with Repaired Cleft PalateDavid Zajac; Fiscal Year: 2007..abstract_text> ..
- cGMP Compartmentalization in Pulmonary Endothelial Barrier DysfunctionEric Schmidt; Fiscal Year: 2008..Understanding how cGMP worsens endothelial leakiness could lead to better therapies of acute lung injury. [unreadable] [unreadable] [unreadable] [unreadable]..
- DOUBLE BLIND STUDY OF MINOCYCLINE IN HDMerit Cudkowicz; Fiscal Year: 2007..Abstract Not Provided. ..
- Dose Study of thymus TransplantationMARY MARKERT; Fiscal Year: 2007..Abstract Not Provided. ..
- Critical Role of Alveolar Fibrin in Acute Lung InjuryGilman Allen; Fiscal Year: 2008..abstract_text> ..
- CLINICAL TRIAL OF TOPIRAMATE IN ALSMerit Cudkowicz; Fiscal Year: 2003..Secondary outcome measures include grip strength, forced vital capacity, the ALS functional rating scale, and the safety and tolerability of topiramate in this population. ..
- Phase I Serum-free cultured thymus transplantation in DiGeorge anomaly, IND9836, MARY MARKERT; Fiscal Year: 2009..The focus of these experiments is the development of thymopoiesis and normal presentation of promiscuously expressed antigens in the thymus. ..
- Symptom Management, Patient-Caregiver Communication, and Outcomes in ICUMARY HAPP; Fiscal Year: 2009....
- Gene Polymorphisms, Inflammation and Outcome from TraumaGRANT O KEEFE; Fiscal Year: 2007..This information will allow clinicians and researchers to more rationally investigate and use specific therapies aimed at reducing the devastating consequences of severe injury and infection. ..
- Respiratory activities of intrinsic tongue musclesE Bailey; Fiscal Year: 2004....
- SPEECH AND RESPIRATORY AERODYNAMICS IN CLEFT PALATEDavid Zajac; Fiscal Year: 2003..It is possible, for example, that therapeutic techniques may be developed that incorporate specific respiratory strategies employed by speakers with cleft palate who exhibit acceptable speech characteristics. ..
- Ventilator Weaning:Processes of Care and CommunicationMARY HAPP; Fiscal Year: 2003....
- Early Assessment of Infants with Cleft Palate Following Surgical RepairDavid Zajac; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Clinical Trial of Ceftriaxone in ALSMerit Cudkowicz; Fiscal Year: 2004..The primary outcome measure for the STAGE III study will be time to death, tracheostomy or permanent assisted ventilation...
- Coenzyme Q10 in Huntington's DiseaseMerit Cudkowicz; Fiscal Year: 2007..abstract_text> ..
- Integrity of the Pulmonary Blood-Gas BarrierJohn West; Fiscal Year: 2007..In addition, at the more basic level, this research is devoted to a fundamental biological dilemma of the lung, namely how the blood-gas barrier combines extreme thinness with immense strength. [unreadable] [unreadable]..
- Cardiovascular Disease (C/V) in Children with Obstructive Sleep Apnea (OSA)Raouf Amin; Fiscal Year: 2007..unreadable] [unreadable]..
- Parathyroid and Thymus Transplants in DiGeorge SyndromeMARY MARKERT; Fiscal Year: 2005..Indirect allorecognition as a mechanism of graft rejection will be assessed by ELISpot. The third aim will assess safety and tolerability. ..
- Chronic Lung Allograft Rejection in MHC-Defined SwineJames Allan; Fiscal Year: 2005..abstract_text> ..
- Dynamics of TCR Repertoire Following Thymus TransplantMARY MARKERT; Fiscal Year: 2008..These findings will have application to thymus and bone marrow transplantation for immunodeficiency and cancer. ..
- COPD Clinical Research Network & Clinical Research Skills Core DevelopmentGerard Criner; Fiscal Year: 2007..abstract_text> ..
- MMP-9-Dependent Vessel Wall Remodeling is NO-DependentGilbert Upchurch; Fiscal Year: 2005....
- Identification and characterization of the DFNB17 geneJohn Greinwald; Fiscal Year: 2006....
- COGNITIVE AND PHYSICAL BASIS OF DISABLEMENTSteven Albert; Fiscal Year: 2005..g., mild disabled) than others. This finding would suggest that disability may be reduced through remediation of motor and cognitive/process skills, as well as by efforts to reduce impairment. ..
- Vascular Functions in Children with Sleep Disorder BreathingRaouf S Amin; Fiscal Year: 2010....
- Effect of leukoreduction on infection risk in traumaAvery Nathens; Fiscal Year: 2004..abstract_text> ..
- Improving Communication with NonSpeaking ICU PatientsMARY HAPP; Fiscal Year: 2007..Statistical analysis will involve hierarchical generalized linear modeling (HGLM) by outcome groups and planned group comparisons using linear contrasts within the context of the HGLM. ..
- IGF-I/ALS TrialEric Sorenson; Fiscal Year: 2007..Secondary endpoints will be tracheostomy free survival and change in ALSFRS score over the 2 year study period...
- DEPRESSION AND DISABILITY IN PATIENTS WITH HEART FAILURECarolyn Turvey; Fiscal Year: 2004..Her long-term career goal is to develop interventions that promote healthy aging amongst elders faced with functional decline. ..
- Bcl-2 and Ca2+ Homeostasis in Cardiac DysfunctionUlrich Schmidt; Fiscal Year: 2006..The ability to modify apoptosis and contractile properties in heart failure would represent an important step towards developing new therapeutic approaches for heart failure. ..
- QUANTITATIVE FUNCTION IN MOTOR NEURON DISEASEEric Sorenson; Fiscal Year: 2004..This will become increasingly important as our population ages, increasing demands for medical and social resources. ..
- DEPRESSION AND END OF LIFE CARE IN ALSSteven Albert; Fiscal Year: 2003..In the final 6-9 months of life, patients must choose (either explicitly or by default) palliation or tracheostomy and long-term mechanical ventilation (LTMV)...
- Interpersonal Psychotherapy for Depression in Heart FailureCarolyn Turvey; Fiscal Year: 2008..Although the focus of the treatment study is patients with heart failure, the long-term goal is to develop a treatment that reduces depression in elders suffering from irreversible loss in function. [unreadable] [unreadable] [unreadable]..