laser in situ keratomileusis

Summary

Summary: A surgical procedure to correct MYOPIA by CORNEAL STROMA subtraction. It involves the use of a microkeratome to make a lamellar dissection of the CORNEA creating a flap with intact CORNEAL EPITHELIUM. After the flap is lifted, the underlying midstroma is reshaped with an excimer laser and the flap is returned to its original position.

Top Publications

  1. ncbi Femtosecond laser flap creation for laser in situ keratomileusis: six-month follow-up of initial U.S. clinical series
    Lee T Nordan
    Scripps Mericos Eye Institute, La Jolla, CA, USA
    J Refract Surg 19:8-14. 2003
  2. ncbi Corneal biomechanical properties in normal, post-laser in situ keratomileusis, and keratoconic eyes
    Dolores Ortiz
    Department of Refractive Surgery, Instituto Oftalmologico de Alicante, VISSUM, Miguel Hernandez University, Medical School, Alicante, Spain
    J Cataract Refract Surg 33:1371-5. 2007
  3. ncbi Arc-scanning very high-frequency digital ultrasound for 3D pachymetric mapping of the corneal epithelium and stroma in laser in situ keratomileusis
    D Z Reinstein
    Margaret M Dyson Vision Research Institute, Department of Ophthalmology, Weill Medical College of Cornell University, New York, NY 10021, USA
    J Refract Surg 16:414-30. 2000
  4. ncbi Laser in situ keratomileusis for myopia and astigmatism: safety and efficacy: a report by the American Academy of Ophthalmology
    Alan Sugar
    Ophthalmic Technology Assessment Committee 2000 2001 Refractive Surgery Panel
    Ophthalmology 109:175-87. 2002
  5. ncbi Laser in situ keratomileusis-induced (presumed) neurotrophic epitheliopathy
    S E Wilson
    Department of Ophthalmology, University of Washington, Seattle, Washington 98195, USA
    Ophthalmology 108:1082-7. 2001
  6. ncbi Comparison of the IntraLase femtosecond laser and mechanical keratomes for laser in situ keratomileusis
    Guy M Kezirian
    Southeastern Eye Center, Greensboro, NC, USA
    J Cataract Refract Surg 30:804-11. 2004
  7. ncbi Laser in situ keratomileusis in 2010 - a review
    Gerard L Sutton
    Department of Ophthalmology, Auckland University, Auckland, New Zealand
    Clin Experiment Ophthalmol 38:192-210. 2010
  8. ncbi Effects of laser in situ keratomileusis on tear production, clearance, and the ocular surface
    L Battat
    Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida, USA
    Ophthalmology 108:1230-5. 2001
  9. ncbi Spherical aberration after laser in situ keratomileusis and photorefractive keratectomy. Clinical results and theoretical models of etiology
    Peter S Hersh
    Institute of Ophthalmology and Visual Science, UMDNJ New Jersey Medical School, Newark, NJ, USA
    J Cataract Refract Surg 29:2096-104. 2003
  10. ncbi Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis
    Farhad Hafezi
    Institute for Refractive and Ophthalmic Surgery, Zurich, Switzerland
    J Cataract Refract Surg 33:2035-40. 2007

Research Grants

  1. Novel Treatment for Post-LASIK Ectasia
    MATTHEW MATTSON; Fiscal Year: 2009
  2. Novel Corneal Implant Materials
    Shiao Chang; Fiscal Year: 2006
  3. PARTNERSHIP FOR RESEARCH IN OPTICAL COHERENCE TOMOGRAPHY
    Joseph Izatt; Fiscal Year: 2001
  4. PARTNERSHIP FOR RESEARCH IN OPTICAL COHERENCE TOMOGRAPHY
    Joseph Izatt; Fiscal Year: 2003
  5. REGULATION OF CORNEAL CELL PROLIFERATION
    Ian Rawe; Fiscal Year: 2003
  6. Snapshot Retinal Imaging Polarimeter
    James Schwiegerling; Fiscal Year: 2007
  7. Control of Eye Melanoma Metastsis
    Hans E Grossniklaus; Fiscal Year: 2010
  8. SUBMACULAR SURGERY TRIALS PATHOLOGY CENTER
    Hans Grossniklaus; Fiscal Year: 2003
  9. Control of Eye Melanoma Metastasis
    Hans Grossniklaus; Fiscal Year: 2003
  10. Ultrasound-Enhanced Delivery of Medications to the Eye
    Ronald Silverman; Fiscal Year: 2008

Detail Information

Publications273 found, 100 shown here

  1. ncbi Femtosecond laser flap creation for laser in situ keratomileusis: six-month follow-up of initial U.S. clinical series
    Lee T Nordan
    Scripps Mericos Eye Institute, La Jolla, CA, USA
    J Refract Surg 19:8-14. 2003
    To evaluate clinical performance of a femtosecond laser for flap creation in laser in situ keratomileusis (LASIK).
  2. ncbi Corneal biomechanical properties in normal, post-laser in situ keratomileusis, and keratoconic eyes
    Dolores Ortiz
    Department of Refractive Surgery, Instituto Oftalmologico de Alicante, VISSUM, Miguel Hernandez University, Medical School, Alicante, Spain
    J Cataract Refract Surg 33:1371-5. 2007
    To compare the biomechanical properties of normal, post-laser in situ keratomileusis (LASIK), and keratoconic corneas evaluated by corneal hysteresis and the corneal resistance factor measured with the Reichert Ocular Response Analyzer (..
  3. ncbi Arc-scanning very high-frequency digital ultrasound for 3D pachymetric mapping of the corneal epithelium and stroma in laser in situ keratomileusis
    D Z Reinstein
    Margaret M Dyson Vision Research Institute, Department of Ophthalmology, Weill Medical College of Cornell University, New York, NY 10021, USA
    J Refract Surg 16:414-30. 2000
    ..thickness mapping, and clinical utility of a new prototype 3D very high-frequency (VHF) (50 MHz) digital ultrasound scanning system for corneal epithelium, flap, and residual stromal thickness after laser in situ keratomileusis (LASIK).
  4. ncbi Laser in situ keratomileusis for myopia and astigmatism: safety and efficacy: a report by the American Academy of Ophthalmology
    Alan Sugar
    Ophthalmic Technology Assessment Committee 2000 2001 Refractive Surgery Panel
    Ophthalmology 109:175-87. 2002
    This document describes laser in situ keratomileusis (LASIK) for myopia and astigmatism and examines the evidence to answer key questions about the efficacy and safety of the procedure.
  5. ncbi Laser in situ keratomileusis-induced (presumed) neurotrophic epitheliopathy
    S E Wilson
    Department of Ophthalmology, University of Washington, Seattle, Washington 98195, USA
    Ophthalmology 108:1082-7. 2001
    ..on the flap compared with eyes with little or no staining on the flap, the first few months after laser in situ keratomileusis (LASIK). None of the eyes in this study had significant preoperative dry eye disease...
  6. ncbi Comparison of the IntraLase femtosecond laser and mechanical keratomes for laser in situ keratomileusis
    Guy M Kezirian
    Southeastern Eye Center, Greensboro, NC, USA
    J Cataract Refract Surg 30:804-11. 2004
    To compare laser in situ keratomileusis (LASIK) results obtained with the femtosecond laser (IntraLase Corp.) to those obtained using 2 popular mechanical microkeratomes.
  7. ncbi Laser in situ keratomileusis in 2010 - a review
    Gerard L Sutton
    Department of Ophthalmology, Auckland University, Auckland, New Zealand
    Clin Experiment Ophthalmol 38:192-210. 2010
    b>Laser in situ keratomileusis has become a widely accepted and commonly performed surgical refractive procedure...
  8. ncbi Effects of laser in situ keratomileusis on tear production, clearance, and the ocular surface
    L Battat
    Bascom Palmer Eye Institute, University of Miami School of Medicine, Miami, Florida, USA
    Ophthalmology 108:1230-5. 2001
    ..ocular surface/lacrimal gland unit in a series of patients before and after undergoing bilateral laser in situ keratomileusis (LASIK). DESIGN: Prospective, noncomparative case series...
  9. ncbi Spherical aberration after laser in situ keratomileusis and photorefractive keratectomy. Clinical results and theoretical models of etiology
    Peter S Hersh
    Institute of Ophthalmology and Visual Science, UMDNJ New Jersey Medical School, Newark, NJ, USA
    J Cataract Refract Surg 29:2096-104. 2003
    ..To assess changes in corneal asphericity after laser refractive surgery and mathematically model possible causes of the changes...
  10. ncbi Corneal collagen crosslinking with riboflavin and ultraviolet A to treat induced keratectasia after laser in situ keratomileusis
    Farhad Hafezi
    Institute for Refractive and Ophthalmic Surgery, Zurich, Switzerland
    J Cataract Refract Surg 33:2035-40. 2007
    ..To determine whether riboflavin and ultraviolet-A (UVA) corneal crosslinking can be used as an alternative therapy to prevent the progression of keratectasia...
  11. ncbi Role of the corneal epithelium in refractive changes following laser in situ keratomileusis for high myopia
    L Spadea
    Department of Ophthalmology, University of L Aquila, Italy
    J Refract Surg 16:133-9. 2000
    ..We evaluated the role of the epithelium following excimer laser in situ keratomileusis (LASIK) performed on highly myopic eyes.
  12. ncbi Exacerbation of Avellino corneal dystrophy after laser in situ keratomileusis
    Xiu Hua Wan
    Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, Brain Korea 21 Project for Med Science, CPO Box 8044, Seoul 120 752, Korea
    Cornea 21:223-6. 2002
    To report a case of Avellino corneal dystrophy that increased in severity 1 year after uncomplicated laser in situ keratomileusis (LASIK) for myopia.
  13. ncbi Central and peripheral corneal thickness measured with optical coherence tomography, Scheimpflug imaging, and ultrasound pachymetry in normal, keratoconus-suspect, and post-laser in situ keratomileusis eyes
    Claudia Maria Prospero Ponce
    Tec de Monterrey, School of Medicine, Monterrey, Mexico
    J Cataract Refract Surg 35:1055-62. 2009
    ..using Scheimpflug imaging (Pentacam), high-speed optical coherence tomography (Visante OCT), and ultrasound (US) pachymetry (Sonogage Corneo-Gage Plus) in normal, keratoconus-suspect, and post-laser in situ keratomileusis (LASIK) eyes.
  14. ncbi Monitoring corneal structures with slitlamp-adapted optical coherence tomography in laser in situ keratomileusis
    Christopher Wirbelauer
    Klinik fur Augenheilkunde, Vivantes Klinikum Neukölln, D 12351 Berlin, Germany
    J Cataract Refract Surg 30:1851-60. 2004
    To monitor corneal structures with slitlamp-adapted optical coherence tomography (OCT) in laser in situ keratomileusis (LASIK).
  15. ncbi Ectasia after laser in situ keratomileusis
    Perry S Binder
    Gordon Binder Vision Institute, San Diego, CA 92112, USA
    J Cataract Refract Surg 29:2419-29. 2003
    Eighty-five cases of post laser in situ keratomileusis ectasia were reviewed and analyzed. Cases of keratoconus or forme fruste keratoconus were eliminated; many remaining case reports lacked key information...
  16. ncbi Wavefront-guided versus wavefront-optimized laser in situ keratomileusis: contralateral comparative study
    Prema Padmanabhan
    Medical and Vision Research Foundation, Tamil Nadu, India
    J Cataract Refract Surg 34:389-97. 2008
    To compare the outcomes of wavefront-guided and wavefront-optimized treatment in fellow eyes of patients having laser in situ keratomileusis (LASIK) for myopia.
  17. ncbi Precision of flap measurements for laser in situ keratomileusis in 4428 eyes
    Gerald W Flanagan
    Gordon Binder Vision Institute, San Diego, CA, USA
    J Refract Surg 19:113-23. 2003
    ..To determine the factor(s) that influence the dimensions and predictability of the LASIK corneal flap with the Automated Corneal Shaper (ACS) or the Summit Krumeich Barraquer microkeratome (SKBM)...
  18. pmc Dry eye associated with laser in situ keratomileusis: Mechanical microkeratome versus femtosecond laser
    Marcella Q Salomao
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Cataract Refract Surg 35:1756-60. 2009
    To compare the incidence of laser in situ keratomileusis (LASIK)-associated dry eye and the need for postoperative cyclosporine A treatment after flap creation with a femtosecond laser and a mechanical microkeratome.
  19. ncbi Intracorneal rings to correct corneal ectasia after laser in situ keratomileusis
    Jorge Alio
    Refractive Surgery and Cornea Unit, Alicante Institute of Ophthalmology, and Miguel Hernández University School of Medicine, Alicante, Spain
    J Cataract Refract Surg 28:1568-74. 2002
    To evaluate the potential of using intrastromal corneal ring technology (Intacs, KeraVision) to correct posterior ectasia after laser in situ keratomileusis (LASIK) for myopia.
  20. ncbi Wound healing in the cornea: a review of refractive surgery complications and new prospects for therapy
    Marcelo V Netto
    The Cole Eye Institute, The Cleveland Clinic Foundation, OH 44195, USA
    Cornea 24:509-22. 2005
    ..The purpose of this review is to provide an overview of the healing response in refractive surgery procedures...
  21. ncbi Infections following laser in situ keratomileusis: an integration of the published literature
    Margaret A Chang
    Wilmer Eye Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Surv Ophthalmol 49:269-80. 2004
    Infections occurring after laser in situ keratomileusis (LASIK) surgery are uncommon, but the number of reports have steadily increased in recent years...
  22. ncbi The effect of nerve growth factor on corneal sensitivity after laser in situ keratomileusis
    Myung Jin Joo
    Wilmer Eye Institute, The Johns Hopkins Hospital, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, USA
    Arch Ophthalmol 122:1338-41. 2004
    To determine if topically administered nerve growth factor (NGF) plays a role in accelerating the recovery of corneal sensitivity after laser in situ keratomileusis (LASIK).
  23. ncbi Peripheral keratitis following laser in situ keratomileusis
    William J Lahners
    Center for Sight, Sarasota, FL 34238, USA
    J Refract Surg 19:671-5. 2003
    To report two different cases of sterile, peripheral keratitis following laser in situ keratomileusis (LASIK).
  24. ncbi Risk assessment for ectasia after corneal refractive surgery
    J Bradley Randleman
    Department of Ophthalmology, Emory University, Atlanta, Georgia, USA
    Ophthalmology 115:37-50. 2008
    ..To analyze the epidemiologic features of ectasia after excimer laser corneal refractive surgery, to identify risk factors for its development, and to devise a screening strategy to minimize its occurrence...
  25. ncbi Comparison of photorefractive keratectomy, astigmatic PRK, laser in situ keratomileusis, and astigmatic LASIK in the treatment of myopia
    Russell N Van Gelder
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, Missouri, USA
    J Cataract Refract Surg 28:462-76. 2002
    To determine factors affecting refractive and visual outcomes in patients treated with astigmatic and spherical photorefractive keratectomy (A-PRK and PRK) and laser in situ keratomileusis (A-LASIK and LASIK).
  26. ncbi Analysis of ectasia after laser in situ keratomileusis: risk factors
    Perry S Binder
    Private Clinical Practice, San Diego, California 92122, USA
    J Cataract Refract Surg 33:1530-8. 2007
    To examine a database of laser in situ keratomileusis (LASIK) procedures for preoperative and operative factors assumed to increase the risk for developing post-LASIK ectasia.
  27. ncbi Noncontact measurements of central corneal epithelial and flap thickness after laser in situ keratomileusis
    Jianhua Wang
    School of Optometry, University of Waterloo, Waterloo, Ontario, Canada
    Invest Ophthalmol Vis Sci 45:1812-6. 2004
    To investigate the changes in the epithelium and flap after laser in situ keratomileusis (LASIK), when measured with optical coherence tomography (OCT).
  28. ncbi Chronic dry eye and regression after laser in situ keratomileusis for myopia
    Julie M Albietz
    Centre for Eye Research, Queensland University of Technology, Kelvin Grove, Australia
    J Cataract Refract Surg 30:675-84. 2004
    To examine the relationship between chronic dry eye and refractive regression after laser in situ keratomileusis (LASIK) for myopia.
  29. ncbi Nerve growth factor concentration and implications in photorefractive keratectomy vs laser in situ keratomileusis
    Hyung Keun Lee
    Institute of Vision Research, Department of Ophthalmology, Yonsei University College of Medicine, 146 92 Shinchon dong, Sudaemoon gu, Seoul 135 720, Korea
    Am J Ophthalmol 139:965-71. 2005
    To determine whether tear nerve growth factor (NGF) concentration correlates with corneal sensation and ocular surface dryness after photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK).
  30. ncbi Comparison of laser in situ keratomileusis and photorefractive keratectomy results: long-term follow-up
    Takashi Miyai
    Miyata Eye Hospital, Miyazaki, Japan
    J Cataract Refract Surg 34:1527-31. 2008
    To compare the results of photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) over a 4-year follow-up.
  31. ncbi Corneal flap thickness and topography changes induced by flap creation during laser in situ keratomileusis
    José L Güell
    Cornea and Refractive Surgery Unit, Instituto de Microcirugia Ocular, Barcelona, Spain
    J Cataract Refract Surg 31:115-9. 2005
    To determine the corneal flap thickness profile produced by 3 microkeratomes and the topographic changes induced by flap creation in laser in situ keratomileusis (LASIK).
  32. ncbi Laser in situ keratomileusis versus surface ablation: visual outcomes and complications
    Faisal Ghadhfan
    Anterior Segment Division, Department of Ophthalmology, Research Department, King Khaled Eye Specialist Hospital, Riyadh, Kingdom of Saudi Arabia
    J Cataract Refract Surg 33:2041-8. 2007
    To compare the visual outcomes and complications of laser in situ keratomileusis (LASIK) with those of surface treatment by laser-assisted subepithelial keratectomy (LASEK), photorefractive keratectomy with mechanical epithelial removal (..
  33. pmc Femtosecond laser in laser in situ keratomileusis
    Marcella Q Salomao
    Cole Eye Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Cataract Refract Surg 36:1024-32. 2010
    Flap creation is a critical step in laser in situ keratomileusis (LASIK). Efforts to improve the safety and predictability of the lamellar incision have fostered the development of femtosecond lasers...
  34. ncbi Dry eye after laser in situ keratomileusis
    I Toda
    Minamiaoyama Eye Clinic, Tokyo, Japan
    Am J Ophthalmol 132:1-7. 2001
    To determine whether patients undergoing laser in situ keratomileusis have postoperative dry eye.
  35. pmc High-speed optical coherence tomography for management after laser in situ keratomileusis
    Mariana Avila
    Doheny Eye Institute and Department of Ophthalmology, Keck School of Medicine of the University of Southern California, Los Angeles, California, USA
    J Cataract Refract Surg 32:1836-42. 2006
    To report applications of optical coherence tomography (OCT) in the management of laser in situ keratomileusis (LASIK) related problems.
  36. ncbi Intracorneal ring segments for iatrogenic keratectasia after laser in situ keratomileusis or photorefractive keratectomy
    Carlo F Lovisolo
    Vista Vision Laser Center, Milan, Italy
    J Refract Surg 18:535-41. 2002
    ..ring segments (Intacs) were inserted in four eyes with iatrogenic keratectasia, 12 to 44 months after laser in situ keratomileusis (LASIK) in two patients and photorefractive keratectomy (PRK) in two patients, in order to avoid ..
  37. ncbi Corneal barrier function, tear film stability, and corneal sensation after photorefractive keratectomy and laser in situ keratomileusis
    Ryohei Nejima
    Meiwakai Medical Foundation, Miyata Eye Hospital, Miyazaki, Japan
    Am J Ophthalmol 139:64-71. 2005
    To compare corneal sensation, corneal barrier function, tear secretion, and tear film stability after photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK).
  38. ncbi Dry eyes and corneal sensation after laser in situ keratomileusis with femtosecond laser flap creation Effect of hinge position, hinge angle, and flap thickness
    Shahzad I Mian
    Department of Ophthalmology and Visual Sciences, W K Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, Michigan 48105, USA
    J Cataract Refract Surg 35:2092-8. 2009
    To determine whether corneal sensation and dry-eye signs and symptoms after myopic laser in situ keratomileusis (LASIK) surgery with a femtosecond laser are affected by varying hinge position, hinge angle, or flap thickness.
  39. pmc Subbasal nerve density and corneal sensitivity after laser in situ keratomileusis: femtosecond laser vs mechanical microkeratome
    Sanjay V Patel
    Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905, USA
    Arch Ophthalmol 128:1413-9. 2010
    To compare changes in subbasal nerve density and corneal sensitivity after laser in situ keratomileusis (LASIK) with the flap created by a femtosecond laser (bladeless) vs a mechanical microkeratome.
  40. ncbi Effect of hinge position on corneal sensation and dry eye after laser in situ keratomileusis using a femtosecond laser
    Shahzad I Mian
    Department of Ophthalmology and Visual Sciences, W K Kellogg Eye Center, University of Michigan Medical School, Ann Arbor, Michigan 48105, USA
    J Cataract Refract Surg 33:1190-4. 2007
    To determine whether hinge position has an effect on corneal sensation and dry-eye symptoms after myopic laser in situ keratomileusis (LASIK) performed with the IntraLase femtosecond laser (IntraLase Corp.).
  41. ncbi Change in intraocular pressure in myopic eyes measured with contact and non-contact tonometers after laser in situ keratomileusis
    M A el Danasoury
    Magrabi Eye Center, Abu Dhabi, United Arab Emirates
    J Refract Surg 17:97-104. 2001
    To study the change in the intraocular pressure (IOP) after laser in situ keratomileusis (LASIK) for correction of myopia.
  42. ncbi Comparison of iris-fixed Artisan lens implantation with excimer laser in situ keratomileusis in correcting myopia between -9.00 and -19.50 diopters: a randomized study
    M Alaa El Danasoury
    Magrabi Eye and Ear Center, Abu Dhabi, United Arab Emirates Magrabi Eye Hospital, Jeddah, Saudi Arabia
    Ophthalmology 109:955-64. 2002
    To compare Artisan lens implantation with laser in situ keratomileusis (LASIK) for the correction of myopia between -9.00 and -19.50 diopters.
  43. ncbi Visual outcomes of wavefront-guided laser in situ keratomileusis in eyes with moderate or high myopia and compound myopic astigmatism
    Simon R Bababeygy
    Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Cataract Refract Surg 34:21-7. 2008
    To evaluate the safety, efficacy, and clinical outcomes of wavefront-guided laser in situ keratomileusis (LASIK) surgery for the treatment of moderate to high myopia and compound myopic astigmatism.
  44. ncbi Increase in corneal asphericity after standard laser in situ keratomileusis for myopia is not inherent to the Munnerlyn algorithm
    Susana Marcos
    Instituto de Optica, Consejo Superior de Investigaciones Cientificas, Madrid, Spain
    J Refract Surg 19:S592-6. 2003
    ..This study tries to resolve this controversy and discusses causes of optical degradation after refractive surgery...
  45. ncbi Anterior corneal optical aberrations induced by laser in situ keratomileusis for hyperopia
    Li Wang
    Cullen Eye Institute, Baylor College of Medicine, Department of Ophthalmology, Houston, Texas 77030, USA
    J Cataract Refract Surg 29:1702-8. 2003
    To evaluate the effects of hyperopic laser in situ keratomileusis (LASIK) on anterior corneal higher-order aberrations (HOAs) (3rd to 6th orders).
  46. ncbi Comparison of Collamer toric implantable [corrected] contact lens implantation and wavefront-guided laser in situ keratomileusis for high myopic astigmatism
    Kazutaka Kamiya
    Department of Ophthalmology, University of Kitasato School of Medicine, Sagamihara, Kanagawa, Japan
    J Cataract Refract Surg 34:1687-93. 2008
    To compare the postoperative visual outcomes after implantation of a Collamer toric implantable contact lens (ICL) and after wavefront-guided laser in situ keratomileusis in high myopic astigmatism.
  47. ncbi Fourier analysis of induced irregular astigmatism. Photorefractive keratectomy versus laser in situ keratomileusis in a bilateral cohort of hyperopic patients
    Andrea Sciscio
    Department of Ophthalmology, St Thomas Hospital, London, England, United Kingdom
    J Cataract Refract Surg 29:1709-17. 2003
    To analyze corneal topographic data by Fourier analysis to determine differences in irregular astigmatism following spherical hyperopic correction by photorefractive keratectomy (PRK) or laser in situ keratomileusis (LASIK).
  48. ncbi Wavefront-guided laser in situ keratomileusis using the WaveScan system for correction of low to moderate myopia with astigmatism: 6-month results in 277 eyes
    Nada S Jabbur
    Refractive Surgery Center, The Wilmer Eye Institute, The Johns Hopkins University Jabbur, Baltimore, Maryland, USA
    J Cataract Refract Surg 31:1493-501. 2005
    ..To assess the safety and effectiveness of wavefront guided LASIK surgery using the Visx WaveScan system for correction of low to moderate myopia with astigmatism...
  49. ncbi Bitoric laser in situ keratomileusis for the correction of simple myopic and mixed astigmatism
    A S Chayet
    CODET Instituto de Oftalmologia, Tijuana, Mexico
    Ophthalmology 108:303-8. 2001
    To evaluate the safety and efficacy of bitoric laser in situ keratomileusis (LASIK) for the correction of simple myopic and mixed astigmatism.
  50. ncbi Comparison of photorefractive keratectomy and laser in situ keratomileusis for the treatment of compound hyperopic astigmatism
    Mohamed Sameh H El-Agha
    Department of Ophthalmology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9057, USA
    J Cataract Refract Surg 29:900-7. 2003
    To compare photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK) for compound hyperopic astigmatism.
  51. ncbi Assessing the accuracy of Orbscan II post-LASIK: apparent keratectasia is paradoxically associated with anterior chamber depth reduction in successful procedures
    Gerard Cairns
    Department of Ophthalmology, University of Auckland, Auckland, New Zealand
    Clin Experiment Ophthalmol 33:147-52. 2005
    ..To establish a relationship between the forward protrusion of the cornea (keratectasia), following successful LASIK, and anterior chamber depth...
  52. ncbi Underestimation of intraocular pressure in eyes after laser in situ keratomileusis
    Ako Arimoto
    Department of Ophthalmology, Musashino Red Cross Hospital, Musashino, Tokyo, Japan
    Jpn J Ophthalmol 46:645-9. 2002
    Retrospectively, we reviewed the records of 65 patients (115 eyes) regarding the intraocular pressure (IOP) after laser in situ keratomileusis (LASIK).
  53. ncbi Decrease in tear secretion and corneal sensitivity after laser in situ keratomileusis
    J M Benitez-Del-Castillo
    Instituto de Investigaciones Oftalmologicas Ramon Castroviejo, Facultad de Medicina, Universidad Complutense, Madrid, Spain
    Cornea 20:30-2. 2001
    PURPOSE: To evaluate tear secretion and corneal sensitivity after laser in situ keratomileusis (LASIK) for the correction of myopia...
  54. ncbi Comparison of myopes and hyperopes after laser in situ keratomileusis monovision
    Daniel B Goldberg
    J Cataract Refract Surg 29:1695-701. 2003
    To compare the results of laser in situ keratomileusis (LASIK) monovision in myopes and hyperopes.
  55. ncbi Delayed-onset multifocal polymicrobial keratitis after laser in situ keratomileusis
    David Ritterband
    Department of Ophthalmology, The New York Eye and Ear Infirmary, New York, New York, USA
    J Cataract Refract Surg 28:898-9. 2002
    ..man who developed discomfort and swelling in his right eye 20 days after uneventful bilateral laser in situ keratomileusis (LASIK). Clinical examination revealed 2 distinct corneal infiltrates beneath the LASIK flap...
  56. ncbi Aggravation of proliferative diabetic retinopathy after laser in situ keratomileusis
    Heshmatollah Ghanbari
    From Feiz Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
    J Cataract Refract Surg 29:2232-3. 2003
    We describe a patient with proliferative diabetic retinopathy who had laser in situ keratomileusis (LASIK)...
  57. ncbi Laser in situ keratomileusis in patients with autoimmune diseases
    Ronald J Smith
    Maloney Vision Institute, Los Angeles, California 90024, USA
    J Cataract Refract Surg 32:1292-5. 2006
    To evaluate the safety of laser in situ keratomileusis (LASIK) in patients with autoimmune diseases.
  58. ncbi Candida parapsilosis keratitis following treatment of epithelial ingrowth after laser in situ keratomileusis
    Renee Solomon
    Ophthalmic Consultants of Long Island, Rockville Centre, NY 11570, USA
    Eye Contact Lens 30:85-6. 2004
    To present a case of Candida parapsilosis following laser in situ keratomileusis (LASIK).
  59. pmc Higher-order aberrations after wavefront-optimized photorefractive keratectomy and laser in situ keratomileusis
    J Bradley Randleman
    Emory University School of Medicine, Atlanta, Georgia, USA
    J Cataract Refract Surg 35:260-4. 2009
    To analyze the changes in higher-order aberrations (HOAs) that occur after wavefront-optimized photorefractive keratectomy (PRK) and laser in situ keratomileusis (LASIK).
  60. ncbi Wavefront-guided laser in situ keratomileusis in the treatment of high myopia by using the CustomVue wavefront platform
    Tharinee Kulkamthorn
    Shiley Eye Center, University of California, San Diego, La Jolla, CA 92093 0946, USA
    Cornea 27:787-90. 2008
    To assess the efficacy, predictability, and safety of wavefront-guided laser in situ keratomileusis (LASIK) in the treatment of high myopia by using the Visx S4 CustomVue wavefront platform.
  61. ncbi Vitreoretinal alterations following laser in situ keratomileusis: clinical and experimental studies
    J D Luna
    , , Argentina
    Graefes Arch Clin Exp Ophthalmol 239:416-23. 2001
    BACKGROUND: The presence of vitreoretinal changes following laser in situ keratomileusis in myopia is evaluated. METHODS: Clinically, 50 patients (100 eyes) with marked anisometropic myopia, 50 low-myopic eyes (<4...
  62. ncbi Visual acuity and higher-order aberrations with wavefront-guided and wavefront-optimized laser in situ keratomileusis
    Claudia E Perez-Straziota
    Emory Vision, Atlanta, Georgia, USA
    J Cataract Refract Surg 36:437-41. 2010
    To compare visual acuity and higher-order aberrations (HOAs) after wavefront-guided and wavefront-optimized laser in situ keratomileusis (LASIK).
  63. ncbi Ocular higher-order aberrations and contrast sensitivity after conventional laser in situ keratomileusis
    Nayori Yamane
    Department of Ophthalmology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan
    Invest Ophthalmol Vis Sci 45:3986-90. 2004
    To investigate prospectively the relation between induced changes in higher-order aberrations of the eye and changes in contrast sensitivity by conventional laser in situ keratomileusis (LASIK) for myopia.
  64. ncbi Visual outcomes after wavefront-guided photorefractive keratectomy and wavefront-guided laser in situ keratomileusis: Prospective comparison
    Majid Moshirfar
    Department of Ophthalmology and Visual Sciences, John A Moran Eye Center, Salt Lake City, Utah 84132, USA
    J Cataract Refract Surg 36:1336-43. 2010
    To compare visual outcomes between wavefront-guided photorefractive keratectomy (PRK) and wavefront-guided laser in situ keratomileusis (LASIK).
  65. ncbi Wavefront analysis in post-LASIK eyes and its correlation with visual symptoms, refraction, and topography
    Maria Regina Chalita
    The Cole Eye Institute, Cleveland Clinic Foundation i32, 9500 Euclid Avenue, Cleveland, OH 44195, USA
    Ophthalmology 111:447-53. 2004
    ..To evaluate the information assessed with the LADARWave wavefront measurement device and correlate it with visual symptoms, refraction, and corneal topography in previously LASIK-treated eyes...
  66. ncbi Intraocular pressure measurements using dynamic contour tonometry after laser in situ keratomileusis
    Claude Kaufmann
    Department of Ophthalmology, University of Zurich, Zurich, Switzerland
    Invest Ophthalmol Vis Sci 44:3790-4. 2003
    Thinning of the corneal stroma by laser in situ keratomileusis (LASIK) results in inaccurate low intraocular pressure (IOP) readings by Goldmann applanation tonometry (GAT)...
  67. ncbi Corneal ectasia induced by laser in situ keratomileusis
    I G Pallikaris
    Department of Ophthalmology, Vardinoyannion Eye Institute of Crete, University of Crete, Heraklio, Greece
    J Cataract Refract Surg 27:1796-802. 2001
    PURPOSE: To identify factors that can lead to corneal ectasia after laser in situ keratomileusis (LASIK).Setting: University refractive surgery center...
  68. ncbi Incidence of vitreoretinal pathologic conditions within 24 months after laser in situ keratomileusis
    J F Arevalo
    Retina and Vitreous Service, Clinica Oftalmologica Centro Caracas, Venezuela
    Ophthalmology 107:258-62. 2000
    To report for the first time a case series of vitreoretinal pathologic conditions after laser in situ keratomileusis (LASIK) and to determine its incidence.
  69. pmc Validation of the Ectasia Risk Score System for preoperative laser in situ keratomileusis screening
    J Bradley Randleman
    Emory University, Department of Ophthalmology, Atlanta, Georgia, USA
    Am J Ophthalmol 145:813-8. 2008
    To validate the Ectasia Risk Score System for identifying patients at high risk for developing ectasia after laser in situ keratomileusis (LASIK).
  70. ncbi Determining in vivo biomechanical properties of the cornea with an ocular response analyzer
    David A Luce
    Reichert Inc, Depew, New York, USA
    J Cataract Refract Surg 31:156-62. 2005
    ..To study the results of an ocular response analyzer (ORA) to determine the biomechanical properties of the cornea and their relationship to intraocular pressure (IOP)...
  71. ncbi Laser in situ keratomileusis flap complications using mechanical microkeratome versus femtosecond laser: retrospective comparison
    Majid Moshirfar
    Department of Ophthalmology and Visual Sciences, University of Utah, Salt Lake City, Utah, USA
    J Cataract Refract Surg 36:1925-33. 2010
    To compare the incidence of flap complications after creation of laser in situ keratomileusis (LASIK) flaps using a zero-compression microkeratome or a femtosecond laser.
  72. ncbi Laser in situ keratomileusis-induced neurotrophic epitheliopathy
    S E Wilson
    Department of Ophthalmology, University of Washington, Seattle, WA 98195, USA
    Am J Ophthalmol 132:405-6. 2001
    To report two cases of laser in situ keratomileusis-induced neurotrophic epitheliopathy with punctate epitheliopathy and rose bengal staining of the corneal flap.
  73. pmc Alterations of extracellular matrix components and proteinases in human corneal buttons with INTACS for post-laser in situ keratomileusis keratectasia and keratoconus
    Ezra Maguen
    Ophthalmology Research, Cedars Sinai Medical Center, Los Angeles, CA 90048, USA
    Cornea 27:565-73. 2008
    To perform an immunohistochemical evaluation of corneas with INTACS for post-laser in situ keratomileusis (LASIK) keratectasia and keratoconus, obtained after corneal transplantation.
  74. ncbi Management of corneal ectasia after laser in situ keratomileusis with INTACS
    Charalambos S Siganos
    Department of Ophthalmology, Vardinoyannion Eye Institute of Crete, University of Crete, Greece
    J Refract Surg 18:43-6. 2002
    To evaluate the safety and efficacy of intrastromal corneal ring segments (ICRS, INTACS, Keravision) for the correction of corneal ectasia after laser in situ keratomileusis (LASIK).
  75. ncbi Assessment of central corneal thickness in normal, keratoconus, and post-laser in situ keratomileusis eyes using Scheimpflug imaging, spectral domain optical coherence tomography, and ultrasound pachymetry
    Dilraj S Grewal
    Grewal Eye Institute, Chandigarh, India
    J Cataract Refract Surg 36:954-64. 2010
    To compare the central corneal thickness (CCT) in normal eyes, eyes with keratoconus, and eyes after laser in situ keratomileusis (LASIK) using 3 methods.
  76. ncbi Comparison of the changes in corneal biomechanical properties after photorefractive keratectomy and laser in situ keratomileusis
    Kazutaka Kamiya
    Department of Ophthalmology, University of Kitasato School of Medicine, Sagamihara, Kanagawa, 228 8555, Japan
    Cornea 28:765-9. 2009
    To compare the postoperative biomechanical properties of the cornea after photorefractive keratectomy (PRK) and after laser in situ keratomileusis (LASIK) in eyes with myopia.
  77. ncbi One thousand consecutive IntraLase laser in situ keratomileusis flaps
    Perry S Binder
    Gordon Binder and Weiss Vision Institute, San Diego, California 92122, USA
    J Cataract Refract Surg 32:962-9. 2006
    To measure laser in situ keratomileusis (LASIK) flap dimensions created with the IntraLase FS (IL) laser (Intralase Corporation).
  78. ncbi Corneal ectasia after laser in situ keratomileusis in patients without apparent preoperative risk factors
    Shawn R Klein
    Cornea Service, Department of Ophthalmology, Rush University Medical Center, Chicago, IL 60612, USA
    Cornea 25:388-403. 2006
    ..To evaluate patients who developed ectasia with no apparent preoperative risk factors...
  79. ncbi Laser in situ keratomileusis in patients with diabetes
    Ioannis Halkiadakis
    Gimbel Eye Centre, Calgary, Alberta, Canada
    J Cataract Refract Surg 31:1895-8. 2005
    To study the outcomes of laser in situ keratomileusis (LASIK) in patients with well-controlled diabetes mellitus.
  80. ncbi Randomized prospective clinical study comparing induced aberrations with IntraLase and Hansatome flap creation in fellow eyes: potential impact on wavefront-guided laser in situ keratomileusis
    Dan B Tran
    Coastal Vision Medical Group, Inc, University of California Irvine, Irvine, California, USA
    J Cataract Refract Surg 31:97-105. 2005
    To measure and compare the changes in objective wavefront aberration and subjective manifest refraction after laser in situ keratomileusis (LASIK) flap creation with a mechanical microkeratome and a femtosecond laser.
  81. ncbi Total and corneal optical aberrations induced by laser in situ keratomileusis for hyperopia
    Lourdes Llorente
    Instituto de Optica Daza de Valdes, Consejo Superior de Investigaciones Cientificas, Madrid, Spain
    J Refract Surg 20:203-16. 2004
    To evaluate changes induced by standard laser in situ keratomileusis (LASIK) for hyperopia on total and corneal optical quality.
  82. ncbi Intraocular lens power calculation after laser in situ keratomileusis for myopia and hyperopia: a standardized approach
    V Feiz
    Department of Ophthalmology, University of Arkansas for Medical Science, USA
    Cornea 20:792-7. 2001
    PURPOSE: (1) To determine the effect of myopic and hyperopic laser in situ keratomileusis (LASIK) on calculation of intraocular lens (IOL) power...
  83. ncbi Clinical results of laser in situ keratomileusis with superior and nasal hinges
    Kyeong Wook Lee
    Department of Ophthalmology, Kangnam St Mary s Hospital, College of Medicine, The Catholic University of Korea, Seoul, South Korea
    J Cataract Refract Surg 29:457-61. 2003
    ..To compare the differences in the clinical results of LASIK with a nasal corneal flap and with a superior corneal flap...
  84. ncbi Corneal higher order wavefront aberrations after hyperopic laser in situ keratomileusis
    Atsuko Nanba
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    J Refract Surg 21:46-51. 2005
    To evaluate the changes in corneal higher order wavefront aberrations after hyperopic laser in situ keratomileusis (LASIK).
  85. ncbi [Analysis of AC/A ratio after myopic excimer laser in situ keratomileusis]
    Xiao ying Wu
    Ophthalmic Laser Center, Xiangya Hospital, Central South University, Changsha 410008, China
    Zhonghua Yan Ke Za Zhi 39:132-5. 2003
    To study the changes of AC/A ratio of myopia after excimer laser in situ keratomileusis (LASIK).
  86. ncbi Comparison of higher-order aberrations after wavefront-guided laser in situ keratomileusis and laser-assisted subepithelial keratectomy
    So Hyang Chung
    Department of Ophthalmology, Yonsei Institute of Vision Research, Yonsei University College of Medicine, Seoul, Korea
    J Cataract Refract Surg 32:779-84. 2006
    To compare the higher-order aberrations (HOAs) in 70 eyes (38 patients) that had wavefront-guided laser in situ keratomileusis (LASIK) with those in 70 eyes (40 patients) that had wavefront-guided laser-assisted subepithelial keratectomy (..
  87. ncbi Correcting the corneal power measurements for intraocular lens power calculations after myopic laser in situ keratomileusis
    H John Shammas
    Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Am J Ophthalmol 136:426-32. 2003
    ..method and a clinically derived method to calculate the correct corneal power for intraocular lens (IOL) power calculations after laser in situ keratomileusis (LASIK) and to compare the results to the commonly used history-derived method.
  88. ncbi Topography-guided laser in situ keratomileusis (TOPOLINK) to correct irregular astigmatism after previous refractive surgery
    Jorge L Alio
    Instituto Oftalmologico de Alicante, Alicante Miguel Hernández University, Alicante, Spain
    J Refract Surg 19:516-27. 2003
    To assess whether topography-driven laser in situ keratomileusis (LASIK) can correct induced corneal irregular astigmatism.
  89. ncbi Comparison of corneal sensitivity and tear function following Epi-LASIK or laser in situ keratomileusis for myopia
    Maria I Kalyvianaki
    Department of Ophthalmology, University Hospital of Heraklion, Crete, Greece
    Am J Ophthalmol 142:669-71. 2006
    To compare the effect of Epi-LASIK or Laser In Situ Keratomileusis (LASIK) on corneal sensitivity and tear function.
  90. ncbi Aberration-sensing and wavefront-guided laser in situ keratomileusis: management of decentered ablation
    Michael Mrochen
    University of Zurich, Dept of Ophthalmology, Switzerland
    J Refract Surg 18:418-29. 2002
    To clarify the feasibility of aberration-sensing and wavefront-guided laser in situ keratomileusis (LASIK) to manage grossly decentered ablation and to discuss the limitations of the technology.
  91. pmc Corneal aberrations and visual acuity after laser in situ keratomileusis: femtosecond laser versus mechanical microkeratome
    Ramón Calvo
    Department of Ophthalmology, Mayo Clinic, Rochester, MN 55905, USA
    Am J Ophthalmol 149:785-93. 2010
    To compare corneal high-order aberrations and visual acuity after laser in situ keratomileusis (LASIK) with the flap created by a femtosecond laser (bladeless) to LASIK with the flap created by a mechanical microkeratome.
  92. ncbi Pocket of fluid in the lamellar interface after penetrating keratoplasty and laser in situ keratomileusis
    Daniel G Dawson
    Arch Ophthalmol 121:894-6. 2003
  93. ncbi Risk factors in interface epithelialization after laser in situ keratomileusis
    Nada S Jabbur
    Refractive Eye Surgery Service, The Wilmer Eye Institute, The Johns Hopkins University School of Medicine, Baltimore, MD 21287 9121, USA
    J Refract Surg 20:343-8. 2004
    To identify risk factors associated with primary and recurrent epithelial ingrowth after laser in situ keratomileusis (LASIK) requiring surgical debridement.
  94. ncbi Reversal of laser in situ keratomileusis-induced ectasia with intraocular pressure reduction
    James Andrew Hiatt
    Boxer Wachler Vision Institute, Beverly Hills, California 90210, USA
    J Cataract Refract Surg 31:1652-5. 2005
    A 40 year-old woman had laser in situ keratomileusis for --7.75 --0.75 x 20 in the right eye...
  95. ncbi A predictive model for postoperative intraocular pressure among patients undergoing laser in situ keratomileusis (LASIK)
    Chia Ching Yang
    Department of Ophthalmology, Taipei County San Chung Hospital, Taipei, Taiwan
    Am J Ophthalmol 141:530-536. 2006
    ....
  96. ncbi Optical coherence tomography for the detection of laser in situ keratomileusis in donor corneas
    Siegfried G Priglinger
    Department of Ophthalmology, Ludwig Maximilians University, Munich, Mathildenstr 8, 80336 Munich, Germany
    Cornea 22:46-50. 2003
    In 2001, more than one million laser in situ keratomileusis (LASIK) procedures were performed worldwide...
  97. ncbi Tonometry after laser in situ keratomileusis treatment
    S Duch
    Department of Ophthalmology, , Barcelona, Spain
    J Glaucoma 10:261-5. 2001
    ..of intraocular pressure measurements by Goldmann applanation tonometry versus pneumotonometry after laser in situ keratomileusis for myopia...
  98. ncbi Improved contrast sensitivity and visual acuity after wavefront-guided laser in situ keratomileusis: in-depth statistical analysis
    Kuang mon Ashley Tuan
    VISX, Inc, Advanced Medical Optics, Inc, Santa Clara, California 95051, USA
    J Cataract Refract Surg 32:215-20. 2006
    To evaluate changes in contrast sensitivity and visual acuity following wavefront-guided laser in situ keratomileusis (LASIK) procedures with the Visx CustomVue system.
  99. ncbi Peripheral sterile corneal infiltrates after refractive surgery
    Tova Lifshitz
    Department of Ophthalmology, Soroka University Medical Center, Ben Gurion University of the Negev, Beer Sheva, Israel
    J Cataract Refract Surg 31:1392-5. 2005
    ..To report 5 eyes of peripheral sterile corneal infiltrates after refractive surgery...
  100. ncbi Bilateral comparison of wavefront-guided versus conventional laser in situ keratomileusis with Bausch and Lomb Zyoptix
    Tae Im Kim
    Department of Ophthalmology, College of Medicine, University of Ulsan, Asan Medical Center, Seoul, Korea
    J Refract Surg 20:432-8. 2004
    ..To evaluate the effectiveness of wavefront-guided laser in situ keratomileusis (LASIK) in reducing the increase of higher order aberration, we compared aberrational change after ..
  101. ncbi Visual performance after implantable collamer lens implantation and wavefront-guided laser in situ keratomileusis for high myopia
    Akihito Igarashi
    Department of Ophthalmology, University of Kitasato School of Medicine, Sagamihara, Kanagawa, Japan
    Am J Ophthalmol 148:164-70.e1. 2009
    To compare postoperative visual function after implantable collamer lens (ICL; STAAR Surgical, Nidau, Switzerland) implantation and after wavefront-guided laser in situ keratomileusis (WFG-LASIK) in eyes with high myopia.

Research Grants25

  1. Novel Treatment for Post-LASIK Ectasia
    MATTHEW MATTSON; Fiscal Year: 2009
    ..PUBLIC HEALTH RELEVANCE: Post-laser in situ keratomileusis (LASIK) ectasia is a serious complication of refractive corneal procedures resulting in progressive ..
  2. Novel Corneal Implant Materials
    Shiao Chang; Fiscal Year: 2006
    ..Surgical methods to treat refractive error by remodeling the cornea, such as laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK), are common in the U.S. An estimated 1...
  3. PARTNERSHIP FOR RESEARCH IN OPTICAL COHERENCE TOMOGRAPHY
    Joseph Izatt; Fiscal Year: 2001
    ....
  4. PARTNERSHIP FOR RESEARCH IN OPTICAL COHERENCE TOMOGRAPHY
    Joseph Izatt; Fiscal Year: 2003
    ....
  5. REGULATION OF CORNEAL CELL PROLIFERATION
    Ian Rawe; Fiscal Year: 2003
    ..used to correct for myopia, and many of these techniques, such as photorefractive keratectomy and laser in situ keratomileusis, disturb the integrity of the epithelium...
  6. Snapshot Retinal Imaging Polarimeter
    James Schwiegerling; Fiscal Year: 2007
    ..Furthermore, the device could potentially be a low-cost add-on to existing fundus cameras, allowing a more widespread utility than existing devices. [unreadable] [unreadable]..
  7. Control of Eye Melanoma Metastsis
    Hans E Grossniklaus; Fiscal Year: 2010
    ..The third aim determines the mechanism of combined angiostatin/IFN control of the micrometastases using methods in the first two aims. ..
  8. SUBMACULAR SURGERY TRIALS PATHOLOGY CENTER
    Hans Grossniklaus; Fiscal Year: 2003
    ..Additionally, eyes obtained post-mortem from patients enrolled in the SST will be studied for pathologic correlation with clinical findings and outcomes. ..
  9. Control of Eye Melanoma Metastasis
    Hans Grossniklaus; Fiscal Year: 2003
    ..Both the IFN and angiostatin will prevent the progression of micrometastases into metastases by anti-angiogenesis. Angiostatin will prevent metastases by an anti-melanoma invasion effect. ..
  10. Ultrasound-Enhanced Delivery of Medications to the Eye
    Ronald Silverman; Fiscal Year: 2008
    ..We will visualize the distribution of the molecules within the sclera, choroid and retina to evaluate transport and characterize any tissue damage that might have occurred microscopically and by apoptosis assays. ..
  11. Corneal Refractive Power Post Refractive Surgery
    CHARLOTTE JOSLIN; Fiscal Year: 2008
    ..The long-term objective to this research is to contribute to the knowledge of IOL power determination in post-refractive surgery patients. ..
  12. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    James Brandt; Fiscal Year: 2008
    ....
  13. Computer-Aided Interpretation of Oculometric Data
    Michael Smolek; Fiscal Year: 2006
    ..For patients, refractive surgery outcomes will be more predictable, and they will benefit from earlier detection of diseases such as cataracts and corneal ectasias. ..
  14. Bridging Barriers to Diabetes Care with Telemedicine
    Richard Davis; Fiscal Year: 2007
    ..Telemedicine may be an effective alternative to traditional health care delivery systems resulting in improved diabetes education and control. ..
  15. Optical Measurement of Choroid to Photoreceptor Distance
    DANIEL NEAL; Fiscal Year: 2002
    ..Medical practice is anticipated to benefit through advancements in automated refraction techniques. ..
  16. Scanning Ocular Aberration Measurement (SAM) System
    EDWIN SARVER; Fiscal Year: 2007
    ..In addition, the ability to measure these aberrations dynamically while the eye is changing focus from a distant to a near object will be provided. [unreadable] [unreadable] [unreadable] [unreadable]..
  17. Shack-Hartmann Corneal Topographer and Aberrometer
    DANIEL NEAL; Fiscal Year: 2005
    ..The long-term benefits will be improved patient care through improved diagnosis and treatment of optical defects of eyes. ..
  18. The Contact Lens and Dry Eye Study
    Jason Nichols; Fiscal Year: 2006
    ..The long-term objective of this research is to contribute to a better understanding of the etiology and risk factors for contact lens-related dry eye so that progress can be made toward its prevention. ..
  19. PATHOGENESIS OF CORNEAL EDEMA AFTER INTRAOCULAR SURGERY
    Henry Edelhauser; Fiscal Year: 2006
    ....
  20. South Carolina Center for Clinical /Translational Resear
    Richard Davis; Fiscal Year: 2006
    ..We expect the CCTR to begin operating as an efficient center for translational research, by the end of the funding period. [unreadable] [unreadable] [unreadable]..
  21. MOLECULAR STUDIES OF THE THIEL-BEHNKE CORNEAL DYSTROPHY
    Richard Yee; Fiscal Year: 2006
    ....
  22. Longitudinal Analysis of Silicone Hydrogel (LASH) Study
    Loretta Szczotka Flynn; Fiscal Year: 2008
    ..224 patients will be enrolled and followed for three years in this longitudinal cohort study. ..
  23. Multi-Resolution Corneal Topography (MRCT)
    EDWIN SARVER; Fiscal Year: 2006
    ..research grant ..
  24. Subjective Refraction by Meridional Power Matching
    EDWIN SARVER; Fiscal Year: 2002
    ..Technological Innovation: Providing an accurate, low-cost, low-maintenance refractor that can be easily transported and used in hostile environments. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE ..
  25. OPTICAL AND RETINAL LIMITS TO HUMAN VISUAL PERFORMANCE
    Larry N Thibos; Fiscal Year: 2010
    ..Project 6. Develop a new concept of wavefront tomography to characterize the 3-dimensional structure of the eye's optical system from a series of wavefront measurements along multiple lines-of-sight. ..