trabeculectomy

Summary

Summary: Any surgical procedure for treatment of glaucoma by means of puncture or reshaping of the trabecular meshwork. It includes goniotomy, trabeculectomy, and laser perforation.

Top Publications

  1. ncbi Intensified postoperative care versus conventional follow-up: a retrospective long-term analysis of 177 trabeculectomies
    Dirk Marquardt
    Department of Ophthalmology, University Hospitals, Josef Schneider Strasse 11, 97080, Wurzburg, Germany
    Graefes Arch Clin Exp Ophthalmol 242:106-13. 2004
  2. ncbi Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up
    Steven J Gedde
    Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Florida, USA
    Am J Ophthalmol 153:789-803.e2. 2012
  3. ncbi Comparison of trabeculectomy with Ex-PRESS miniature glaucoma device implanted under scleral flap
    Peter J G Maris
    Hamilton Eye Institute, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
    J Glaucoma 16:14-9. 2007
  4. pmc Postoperative complications in the Tube Versus Trabeculectomy (TVT) study during five years of follow-up
    Steven J Gedde
    Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Florida, USA
    Am J Ophthalmol 153:804-814.e1. 2012
  5. ncbi Resident-performed Ex-PRESS shunt implantation versus trabeculectomy
    Michael I Seider
    Department of Ophthalmology, University of California, San Francisco, CA, USA
    J Glaucoma 21:469-74. 2012
  6. ncbi Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial
    M Cristina Leske
    Department of Preventive Medicine, Stony Brook University School of Medicine, Health Sciences Center, L3 086, Stony Brook, NY 11794 8036, USA
    Arch Ophthalmol 121:48-56. 2003
  7. ncbi Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial
    Anders Heijl
    Department of Ophthalmology, Malmo University Hospital, SE 20502 Malmo, Sweden
    Arch Ophthalmol 120:1268-79. 2002
  8. pmc Biodegradable collagen matrix implant vs mitomycin-C as an adjuvant in trabeculectomy: a 24-month, randomized clinical trial
    S Cillino
    Department of Experimental Biomedicine and Clinical Neuroscience, Ophthalmology Section, University of Palermo Italy, Palermo, Italy
    Eye (Lond) 25:1598-606. 2011
  9. ncbi Inhibition of vascular endothelial growth factor reduces scar formation after glaucoma filtration surgery
    Zhongqiu Li
    Laboratory of Ophthalmology, Catholic University Leuven, Leuven, Belgium
    Invest Ophthalmol Vis Sci 50:5217-25. 2009
  10. ncbi Novel glaucoma procedures: a report by the American Academy of Ophthalmology
    Brian A Francis
    University of Southern California, Los Angeles, CA, USA
    Ophthalmology 118:1466-80. 2011

Research Grants

Detail Information

Publications265 found, 100 shown here

  1. ncbi Intensified postoperative care versus conventional follow-up: a retrospective long-term analysis of 177 trabeculectomies
    Dirk Marquardt
    Department of Ophthalmology, University Hospitals, Josef Schneider Strasse 11, 97080, Wurzburg, Germany
    Graefes Arch Clin Exp Ophthalmol 242:106-13. 2004
    To evaluate the long-term outcome of trabeculectomy under the conditions of intensified postoperative care (IPC) compared with conventional follow-up.
  2. ncbi Treatment outcomes in the Tube Versus Trabeculectomy (TVT) study after five years of follow-up
    Steven J Gedde
    Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Florida, USA
    Am J Ophthalmol 153:789-803.e2. 2012
    To report 5-year treatment outcomes in the Tube Versus Trabeculectomy (TVT) Study.
  3. ncbi Comparison of trabeculectomy with Ex-PRESS miniature glaucoma device implanted under scleral flap
    Peter J G Maris
    Hamilton Eye Institute, University of Tennessee Health Sciences Center, Memphis, TN 38163, USA
    J Glaucoma 16:14-9. 2007
    To evaluate the Ex-PRESS miniature implant (Model R 50) placed under partial-thickness scleral flap compared with standard trabeculectomy.
  4. pmc Postoperative complications in the Tube Versus Trabeculectomy (TVT) study during five years of follow-up
    Steven J Gedde
    Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Florida, USA
    Am J Ophthalmol 153:804-814.e1. 2012
    To describe postoperative complications encountered in the Tube Versus Trabeculectomy (TVT) Study during 5 years of follow-up.
  5. ncbi Resident-performed Ex-PRESS shunt implantation versus trabeculectomy
    Michael I Seider
    Department of Ophthalmology, University of California, San Francisco, CA, USA
    J Glaucoma 21:469-74. 2012
    To compare outcomes between resident-performed trabeculectomy and Ex-PRESS shunt implantation.
  6. ncbi Factors for glaucoma progression and the effect of treatment: the early manifest glaucoma trial
    M Cristina Leske
    Department of Preventive Medicine, Stony Brook University School of Medicine, Health Sciences Center, L3 086, Stony Brook, NY 11794 8036, USA
    Arch Ophthalmol 121:48-56. 2003
    ..To assess factors for progression in the Early Manifest Glaucoma Trial (EMGT), including the effect of EMGT treatment...
  7. ncbi Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial
    Anders Heijl
    Department of Ophthalmology, Malmo University Hospital, SE 20502 Malmo, Sweden
    Arch Ophthalmol 120:1268-79. 2002
    ..To provide the results of the Early Manifest Glaucoma Trial, which compared the effect of immediately lowering the intraocular pressure (IOP), vs no treatment or later treatment, on the progression of newly detected open-angle glaucoma...
  8. pmc Biodegradable collagen matrix implant vs mitomycin-C as an adjuvant in trabeculectomy: a 24-month, randomized clinical trial
    S Cillino
    Department of Experimental Biomedicine and Clinical Neuroscience, Ophthalmology Section, University of Palermo Italy, Palermo, Italy
    Eye (Lond) 25:1598-606. 2011
    To verify the safety and efficacy of Ologen (OLO) implant as adjuvant compared with low-dosage mitomycin-C (MMC) in trabeculectomy.
  9. ncbi Inhibition of vascular endothelial growth factor reduces scar formation after glaucoma filtration surgery
    Zhongqiu Li
    Laboratory of Ophthalmology, Catholic University Leuven, Leuven, Belgium
    Invest Ophthalmol Vis Sci 50:5217-25. 2009
    ....
  10. ncbi Novel glaucoma procedures: a report by the American Academy of Ophthalmology
    Brian A Francis
    University of Southern California, Los Angeles, CA, USA
    Ophthalmology 118:1466-80. 2011
    ....
  11. ncbi Utility of bleb imaging with anterior segment optical coherence tomography in clinical decision-making after trabeculectomy
    Mandeep Singh
    Department of Ophthalmology, National University Hospital, Singapore 119074
    J Glaucoma 18:492-5. 2009
    To determine if imaging of blebs with anterior segment optical coherence tomography (ASOCT) affects clinical decision-making with regard to laser suture lysis (LSL) after trabeculectomy.
  12. ncbi A prospective randomised trial of trabeculectomy using mitomycin C vs an ologen implant in open angle glaucoma
    A Rosentreter
    Department of Ophthalmology, University of Cologne, Koln, Germany
    Eye (Lond) 24:1449-57. 2010
    The aim of this study is to assess the efficacy and complications of trabeculectomy with a biodegradable implant (ologen implant) vs trabeculectomy using mitomycin C (MMC) in patients with medically uncontrolled open-angle glaucoma in a ..
  13. ncbi A comparison of the Ex-PRESS™ mini glaucoma shunt with standard trabeculectomy in the surgical treatment of glaucoma
    Lionel Marzette
    Duke University Eye Center, Durham, NC 27710, USA
    Ophthalmic Surg Lasers Imaging 42:453-9. 2011
    To compare the success and complication rates of patients with glaucoma who had an Ex-PRESS mini glaucoma shunt device implantation (Optonol, Ltd., Neve Ilan, Israel) to those who had conventional trabeculectomy.
  14. ncbi Imaging of blebs after phacotrabeculectomy with Ologen collagen matrix implants
    P Y Boey
    Singapore National Eye Centre, 11 Third Hospital Avenue, Singapore 168751, Singapore
    Br J Ophthalmol 95:340-4. 2011
    ..To analyse blebs of phacotrabeculectomies performed with Ologen collagen implants (ProTop & MediKing, Taipei, Taiwan) and to compare these with blebs of mitomycin C (MMC)–augmented phacotrabeculectomies...
  15. ncbi In vivo confocal microscopy study of blebs after filtering surgery
    Antoine Labbe
    Department of Ophthalmology III, Quinze Vingts National Ophthalmology Hospital, Paris, France
    Ophthalmology 112:1979. 2005
    ..To analyze bleb structure after filtering surgery at the cellular level using a new generation in vivo confocal microscope...
  16. pmc Ex-PRESS implantation versus trabeculectomy in uncontrolled glaucoma: a meta-analysis
    Wei Wang
    Zhongshan Ophthalmic Center, State Key Laboratory of Ophthalmology, Sun Yat Sen University, Guangzhou, People s Republic of China
    PLoS ONE 8:e63591. 2013
    To evaluate the efficacy and tolerability of Ex-PRESS implantation (Ex-Press) compared with trabeculectomy (Trab) in the treatment of patients with uncontrolled glaucoma.
  17. ncbi Efficacy and safety of trabeculectomy vs nonpenetrating surgical procedures: a systematic review and meta-analysis
    Eliana Rulli
    Clinical Research Laboratory, IRCCS Istituto di Ricerche Farmacologiche Mario Negri, Milan, Italy
    JAMA Ophthalmol 131:1573-82. 2013
    To date, only a few studies have directly compared nonpenetrating surgery (NPS) and trabeculectomy (TE)...
  18. pmc Comparison of trabeculectomy and Ex-PRESS implantation in fellow eyes of the same patient: a prospective, randomised study
    E Dahan
    Department of Ophthalmology, University of Witwatersrand, Johannesburg, South Africa
    Eye (Lond) 26:703-10. 2012
    To compare intraocular pressure (IOP) over time after standard trabeculectomy vs Ex-PRESS implantation in patients with bilateral primary open-angle glaucoma (POAG).
  19. ncbi Current variations of glaucoma filtration surgery
    Sarwat Salim
    Hamilton Eye Institute, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    Curr Opin Ophthalmol 23:89-95. 2012
    b>Trabeculectomy continues to be the most effective incisional surgery for uncontrolled glaucoma. Since its introduction by Cairns in 1968, the procedure has undergone numerous modifications...
  20. ncbi The prognostic value of the wuerzburg bleb classification score for the outcome of trabeculectomy
    Thomas Klink
    Department of Ophthalmology, Julius Maximilian University, Wuerzburg, Germany
    Ophthalmologica 225:55-60. 2011
    ..score (WBCS) aims at an objective and standardized assessment of the developing filtering bleb after trabeculectomy, in order to detect and treat bleb scarring at the earliest possible stage of development...
  21. ncbi Long-term outcomes of needle revision of trabeculectomy blebs with mitomycin C and 5-fluorouracil: a comparative safety and efficacy report
    Nitin Anand
    Department of Ophthalmology, Calderdale and Huddersfield NHS Trust, Huddersfield Royal Infirmary, Huddersfield
    J Glaucoma 18:513-20. 2009
    To report the long-term comparative outcomes for needle revision with 5-fluorouracil (5-FU) and mitomycin C (MMC) of failed trabeculectomy blebs.
  22. ncbi A twenty-year follow-up study of trabeculectomy: risk factors and outcomes
    John Landers
    Department of Ophthalmology, Addenbrooke s Hospital, Cambridge, United Kingdom
    Ophthalmology 119:694-702. 2012
    This study was undertaken to determine the performance of trabeculectomy surgery over a 20-year period and examine the associations between outcome and risk factors for trabeculectomy failure.
  23. ncbi Needling revision of trabeculectomies bleb morphology and long-term survival
    Alan P Rotchford
    Department of Ophthalmology, Queen s Medical Centre, Nottingham University Hospitals National Health Service Trust, Nottingham, United Kingdom
    Ophthalmology 115:1148-1153.e4. 2008
    To assess the long-term success rate and to determine factors that predict survival after 5-fluorouracil-augmented needling revision of poorly functioning trabeculectomy blebs.
  24. ncbi Monocyte modulation of aqueous outflow and recruitment to the trabecular meshwork following selective laser trabeculoplasty
    Jorge A Alvarado
    Department of Ophthalmology, University of California, San Francisco, CA 94143 0730, USA
    Arch Ophthalmol 128:731-7. 2010
    ....
  25. ncbi The Ex-PRESS glaucoma shunt versus trabeculectomy in open-angle glaucoma: a prospective randomized study
    Leo A M S de Jong
    Ophthalmology Department, Academic Medical Centre, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands
    Adv Ther 26:336-45. 2009
    ..The purpose of this study was to establish the efficacy and safety of the Ex-PRESS (Optonol Ltd., Neve Ilan, Israel) mini glaucoma shunt in open-angle glaucoma...
  26. ncbi Incidence of late-onset bleb-related complications following trabeculectomy with mitomycin
    Peter W DeBry
    Department of Ophthalmology and Visual Sciences, University of Wisconsin, Madison, 2870 University Ave, Suite 206, Madison, WI 53705, USA
    Arch Ophthalmol 120:297-300. 2002
    To determine the incidence of late-onset bleb-related complications following trabeculectomy with mitomycin and to report the management and outcome of bleb leaks following trabeculectomy with mitomycin.
  27. ncbi Comparison of the morphologic changes after selective laser trabeculoplasty and argon laser trabeculoplasty in human eye bank eyes
    T R Kramer
    Emory Eye Center, Emory University School of Medicine, 1365-B Clifton Road N.E, Atlanta, GA 30322, USA
    Ophthalmology 108:773-9. 2001
    ....
  28. ncbi Interim clinical outcomes in the Collaborative Initial Glaucoma Treatment Study comparing initial treatment randomized to medications or surgery
    P R Lichter
    Department of Ophthalmology and Visual Sciences, Kellogg Eye Center, The University of Michigan, Ann Arbor, Michigan 48105, USA
    Ophthalmology 108:1943-53. 2001
    ..trial, 607 patients with newly diagnosed open-angle glaucoma were initially treated with either medication or trabeculectomy (with or without 5-fluorouracil)...
  29. ncbi Intraocular pressure response of capsular glaucoma and primary open-angle glaucoma to selective Nd:YAG laser trabeculoplasty: a prospective, comparative clinical trial
    T Gracner
    Department of Ophthalmology, Maribor Teaching Hospital, Slovenia
    Eur J Ophthalmol 12:287-92. 2002
    ..To compare the intraocular pressure (IOP) response of uncontrolled capsular glaucoma (CG) and primary open-angle glaucoma (POAG) to selective laser trabeculoplasty (SLT) in a prospective clinical trial...
  30. ncbi Trabeculectomy with mitomycin C versus Ahmed glaucoma implant with mitomycin C for treatment of pediatric aphakic glaucoma
    Mohammad Pakravan
    Labbafinejad Medical Center, Shaheed Beheshti Medical University, Tehran, Iran
    J Glaucoma 16:631-6. 2007
    To compare trabeculectomy with mitomycin C (T+MMC) and Ahmed glaucoma implant with MMC (AGI+MMC) in treatment of aphakic glaucoma in children below 16 years of age.
  31. ncbi Effectiveness of trabeculectomy on glaucoma patients in Ibadan
    A M Agbeja-Baiyeroju
    Department of Ophthalmology, University College Hospital, Ibadan
    Afr J Med Med Sci 30:39-42. 2001
    This study was designed to determine the effectiveness of trabeculectomy on African patients. All patients who underwent trabeculectomy over a 10-year period, January 1987 to December 1996 were included in the study...
  32. ncbi Surgical complications in the Tube Versus Trabeculectomy Study during the first year of follow-up
    Steven J Gedde
    Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, 900 NW 17th Street, Miami, FL 33136, USA
    Am J Ophthalmol 143:23-31. 2007
    To describe the intraoperative and postoperative complications encountered during the first year of follow-up in the Tube Versus Trabeculectomy (TVT) Study.
  33. ncbi Trabeculectomy with mitomycin C in pseudophakic patients with open-angle glaucoma: outcomes and risk factors for failure
    Hector Fontana
    Glaucoma Division, Jules Stein Eye Institute, University of California, Los Angeles, California, USA
    Am J Ophthalmol 141:652-9. 2006
    To evaluate tonometric outcomes of trabeculectomy with mitomycin C in pseudophakic patients with open-angle glaucoma and associated risk factors for failure.
  34. ncbi Control of filtering bleb structure through tissue bioengineering: An animal model
    Henry Shen Lih Chen
    Glaucoma Service, Department of Ophthalmology, Chang Gung Memorial Hospital, Taipei, Taiwan
    Invest Ophthalmol Vis Sci 47:5310-4. 2006
    To devise a means of providing controlled resistance between the anterior chamber and the subconjunctival space after trabeculectomy by implantation of a biodegradable, porous collagen matrix.
  35. ncbi [Postoperative outcomes after combined glaucoma surgery. Comparison of ex-press miniature implant with standard trabeculectomy]
    R Gallego-Pinazo
    Hospital Universitario La Fe de Valencia, Valencia, Espana
    Arch Soc Esp Oftalmol 84:293-7. 2009
    To evaluate postoperative outcomes and success after combined phacoemulsification and glaucoma surgery with Ex-PRESS miniature implant compared with combined surgery with standard trabeculectomy.
  36. ncbi Phacoemulsification in eyes with functioning filtering blebs: a prospective study
    Gema Rebolleda
    Hospital Ramon y Cajal, Ophthalmology Department, Glaucoma Unit, Madrid, Spain
    Ophthalmology 109:2248-55. 2002
    ..To evaluate the effect of phacoemulsification on intraocular pressure (IOP) control in eyes with a previous functioning filtering bleb and no glaucoma medication...
  37. ncbi Measuring visual field progression in the Early Manifest Glaucoma Trial
    Anders Heijl
    Department of Ophthalmology, Malmo University Hospital, Malmo, Sweden
    Acta Ophthalmol Scand 81:286-93. 2003
    ..This paper provides estimates of the amount of visual field worsening required to reach the EMGT definition of definite perimetric progression...
  38. ncbi The singapore 5-Fluorouracil trabeculectomy study: effects on intraocular pressure control and disease progression at 3 years
    Tina T Wong
    Singapore National Eye Center, Singapore and Singapore Eye Research Institute, Singapore
    Ophthalmology 116:175-84. 2009
    To report 3-year results of a randomized, controlled trial comparing the use of a single application of 5-fluorouracil (5-FU) with placebo in trabeculectomy surgery.
  39. ncbi Comparison of surgical outcomes between canaloplasty and trabeculectomy at 12 months' follow-up
    Ramesh S Ayyala
    Department of Ophthalmology, Tulane School of Medicine, Tulane University, New Orleans, Louisiana 70112, USA
    Ophthalmology 118:2427-33. 2011
    To compare operative outcomes of patients after canaloplasty and trabeculectomy through 12 months' follow-up.
  40. ncbi Practice preferences for glaucoma surgery: a survey of the American Glaucoma Society in 2008
    Manishi A Desai
    Boston Medical Center, Boston University School of Medicine, Boston, Massachusetts, USA
    Ophthalmic Surg Lasers Imaging 42:202-8. 2011
    ..To evaluate glaucoma surgical practice patterns among members of the American Glaucoma Society (AGS)...
  41. ncbi Effect of temporal corneal phacoemulsification on intraocular pressure in eyes with prior trabeculectomy with an antimetabolite
    Kala Swamynathan
    Department of Ophthalmology, Indiana University, 702 Rotary Circle, Indianapolis, IN 46202, USA
    Ophthalmology 111:674-8. 2004
    To evaluate the effect of temporal corneal phacoemulsification on intraocular pressure (IOP) in eyes after primary trabeculectomy with intraoperative fluorouracil (5-FU) or mitomycin C (MMC).
  42. ncbi The changing conceptual basis of trabeculectomy: a review of past and current surgical techniques
    M Reza Razeghinejad
    Wills Eye Institute, Jefferson Medical College, Philadelphia, Pennsylvania 19107, USA
    Surv Ophthalmol 57:1-25. 2012
    ..would allow aqueous to leave without producing a filtering bleb; however, it became apparent that Cairns's "trabeculectomy" only worked when a filtering bleb developed...
  43. ncbi Comparison of limbus-based and fornix-based trabeculectomy: success, bleb-related complications, and bleb morphology
    Jason F Solus
    Glaucoma Service and Dana Center for Preventive Ophthalmology, Wilmer Ophthalmological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    Ophthalmology 119:703-11. 2012
    To compare the success and complications of trabeculectomy performed with limbus-based and fornix-based conjunctival approaches.
  44. ncbi Aqueous shunts in the treatment of glaucoma
    Sameh Mosaed
    The Gavin Herbert Eye Institute, University of California, Irvine, CA, USA
    Expert Rev Med Devices 7:661-6. 2010
    ..The standard procedure over the past 40 years has been trabeculectomy, first described in 1968...
  45. ncbi Sutureless revision of overhanging filtering blebs
    Sarah Anis
    Department of Ophthalmology, The New York Eye and Ear Infirmary, 310 E 14th Street, New York, NY 10003, USA
    Arch Ophthalmol 124:1317-20. 2006
    ..of a technique for sutureless surgical revision of symptomatic corneal overhanging filtering blebs after trabeculectomy using mitomycin in 6 eyes in 6 patients...
  46. ncbi Ab interno trabeculectomy: outcomes in exfoliation versus primary open-angle glaucoma
    Jessica L M Ting
    Department of Ophthalmology, University of Alberta, Royal Alexandra Hospital, Edmonton, Alberta, Canada
    J Cataract Refract Surg 38:315-23. 2012
    To compare outcomes in exfoliation glaucoma versus primary open-angle glaucoma (POAG) after ab interno trabeculectomy alone (Trabectome) or in combination with cataract surgery and intraocular lens (IOL) implantation.
  47. ncbi Randomized, prospective, comparative trial of EX-PRESS glaucoma filtration device versus trabeculectomy (XVT study)
    Peter A Netland
    University of Virginia School of Medicine, Charlottesville, Virginia Electronic address
    Am J Ophthalmol 157:433-440.e3. 2014
    To compare the clinical outcomes of the EX-PRESS glaucoma filtration device placed under a partial-thickness scleral flap with trabeculectomy.
  48. ncbi Trabeculectomy with mitomycin-C in the treatment of pediatric glaucomas
    P A Sidoti
    Department of Ophthalmology, The New York Eye and Ear Infirmary, New York 10003, USA
    Ophthalmology 107:422-9. 2000
    To evaluate the effectiveness and safety of trabeculectomy with mitomycin-C (MMC) in the management of childhood glaucomas.
  49. ncbi Reversal of lamina cribrosa displacement and thickness after trabeculectomy in glaucoma
    Eun Ji Lee
    Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea
    Ophthalmology 119:1359-66. 2012
    ..To investigate the response of the lamina cribrosa (LC) and prelaminar tissue to glaucoma surgery using spectral-domain optical coherence tomography (SD-OCT) and to determine the factors influencing such responses...
  50. ncbi Ethnic differences in glaucoma: prevalence, management, and outcome
    Sonal D Wadhwa
    Department of Ophthalmology and Visual Sciences, University of Maryland, Baltimore, Maryland 21201, USA
    Curr Opin Ophthalmol 16:101-6. 2005
    ..The purpose of this article is to provide a review of the literature regarding the prevalence, management, and outcome of glaucoma among different ethnic populations...
  51. ncbi Late complications after glaucoma filtering surgery with adjunctive 5-fluorouracil
    U Ticho
    Department of Ophthalmology, Hadassah University Hospital, Jerusalem, Israel
    Am J Ophthalmol 115:506-10. 1993
    ..9%), and a transient, mild iridocyclitis in nine eyes (8.6%). Thus, adjunctive fluorouracil after filtering surgery may entail various, mainly bleb-related, late side effects and complications...
  52. ncbi Intraoperative mitomycin C versus intraoperative 5-fluorouracil for trabeculectomy: a systematic review and meta-analysis
    Zhong Jie Lin
    Department of Ophthalmology, Shanghai Changzheng Hospital, Second Military Medical University, Shanghai, China
    J Ocul Pharmacol Ther 28:166-73. 2012
    The aim of this study was to assess the intraoperative application of mitomycin C (MMC) compared to 5-fluorouracil (5-FU) on the outcome of trabeculectomy and to examine the balance of risk and benefit.
  53. ncbi Interobserver variability of the Würzburg bleb classification score
    Thomas Klink
    Department of Ophthalmology, Julius Maximilian University, Wurzburg, Germany
    Ophthalmologica 222:408-13. 2008
    ..The Würzburg bleb classification score (WBCS) serves to assess filtering blebs in a standardized fashion. The purpose of this prospective masked agreement study was to evaluate the WBCS interobserver variability...
  54. ncbi Randomized comparison of the intraocular pressure-lowering effect of phacoviscocanalostomy and phacotrabeculectomy
    Hiroshi Kobayashi
    Department of Ophthalmology, Faculty of Medicine, Saga University, Saga, Japan
    Ophthalmology 114:909-14. 2007
    To compare the intraocular pressure (IOP)-lowering effect of combined viscocanalostomy and phacoemulsification and combined trabeculectomy and phacoemulsification with mitomycin C in eyes with primary open-angle glaucoma.
  55. ncbi Outcomes after Descemet stripping endothelial keratoplasty in glaucoma patients with previous trabeculectomy and tube shunt implantation
    Christophe Wiaux
    Jules Stein Eye Institute, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA
    Cornea 30:1304-11. 2011
    ..To describe the incidence of intraoperative and postoperative complications and visual outcomes in eyes with previous penetrating glaucoma surgery undergoing Descemet stripping endothelial keratoplasty (DSEK)...
  56. ncbi Effect of cataract surgery on intraocular pressure in eyes with previous trabeculectomy
    H Mietz
    Department of Ophthalmology, University of Cologne, Germany
    Graefes Arch Clin Exp Ophthalmol 239:763-9. 2001
    To determine the course of the intraocular pressure in eyes in which cataract surgery was performed after trabeculectomy.
  57. ncbi Optic nerve head circulation after intraocular pressure reduction achieved by trabeculectomy
    Y Tamaki
    Department of Ophthalmology, University of Tokyo School of Medicine, Tokyo, Japan
    Ophthalmology 108:627-32. 2001
    OBJECTIVE: To study the effects of trabeculectomy and needling revision of poorly functioning blebs on the optic nerve head (ONH) circulation in patients with primary open-angle glaucoma (POAG)...
  58. ncbi [Follow-up of trabeculectomy. Complications and therapeutic consequences]
    G Picht
    , Joseph-Schneider-Strasse 11,
    Ophthalmologe 98:629-34. 2001
    BACKGROUND: Intensive follow-up after trabeculectomy is important for long-term success. In the postoperative period, complications must be detected early in order to initiate adequate therapeutic measures...
  59. ncbi Deep sclerectomy combined with trabeculectomy in pediatric glaucoma
    Michael Feusier
    Glaucoma Unit, Jules Gonin Eye Hospital, University of Lausanne, Lausanne, Switzerland
    Ophthalmology 116:30-8. 2009
    To evaluate the outcomes of combined deep sclerectomy and trabeculectomy (penetrating deep sclerectomy) in pediatric glaucoma.
  60. ncbi Phacoemulsification and trabeculotomy combined with goniosynechialysis for uncontrollable chronic angle-closure glaucoma
    Yoshiaki Kiuchi
    Department of Ophthalmology and Visual Sciences, Hiroshima University, Hiroshima, Japan
    Ophthalmic Surg Lasers Imaging 41:348-54. 2010
    ..To assess and explore the effectiveness of phacoemulsification and trabeculotomy combined with goniosynechialysis in lowering intraocular pressure in eyes with uncontrollable chronic angle-closure glaucoma...
  61. ncbi Intraocular pressure control after clear corneal phacoemulsification in eyes with previous trabeculectomy: a controlled study
    Asli Inal
    Beyoglu Eye Education and Research Hospital, Istanbul, Turkey
    Acta Ophthalmol Scand 83:554-60. 2005
    To compare intraocular pressure (IOP) control in eyes with or without clear corneal phacoemulsification following trabeculectomy.
  62. pmc Analysis of bleb morphology after trabeculectomy with Visante anterior segment optical coherence tomography
    Christopher Kai Shun Leung
    Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Hong Kong Eye Hospital, 147K Argyle Street, Kowloon, Hong Kong, PRC
    Br J Ophthalmol 91:340-4. 2007
    To describe the use of anterior segment optical coherence tomography (OCT) in imaging intrableb morphology after trabeculectomy.
  63. ncbi Combined trabeculectomy and vitrectomy for pseudophakic malignant glaucoma and extensive peripheral anterior synechia-induced secondary glaucoma
    Yi Yu Tsai
    Department of Ophthalmology, National Cheng Kung University Hospital, Tainan, Taiwan
    J Cataract Refract Surg 30:715-7. 2004
    We report combined trabeculectomy and vitrectomy in a 66-year-old woman with combined-mechanism glaucoma. Trabeculectomy supplemented with mitomycin-C was done first...
  64. ncbi Post-operative complication of trabeculectomy in Ibadan, Nigeria: outcome of 1-year follow-up
    A O Ashaye
    Department of Ophthalmology, University College Hospital, Ibadan, Oyo, Nigeria
    Eye (Lond) 23:448-52. 2009
    To describe the post-operative complications reported in patients who had trabeculectomy with and without antimetabolite in UCH, Ibadan between 1999 and 2003 and the success rate achieved in term of the post-operative intraocular pressure ..
  65. ncbi Assessment of bleb morphologic features and postoperative outcomes after Ex-PRESS drainage device implantation versus trabeculectomy
    Travis J Good
    Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado 80045, USA
    Am J Ophthalmol 151:507-13.e1. 2011
    To investigate bleb morphologic features and postoperative outcomes after Ex-PRESS drainage device (Alcon Laboratories) implantation versus trabeculectomy.
  66. ncbi Long-term effect of phacoemulsification on intraocular pressure after trabeculectomy
    Agnes Derbolav
    Department of Ophthalmology, University of Vienna, Vienna, Austria
    J Cataract Refract Surg 28:425-30. 2002
    To evaluate the effect of temporal clear corneal phacoemulsification on intraocular pressure (IOP) in eyes that have had trabeculectomy.
  67. ncbi Descemet stripping automated endothelial keratoplasty in eyes with previous trabeculectomy and tube shunt procedures: intraoperative and early postoperative complications
    Paul M Phillips
    Devers Eye Institute, Portland, OR, USA
    Cornea 29:534-40. 2010
    ..To evaluate the intraoperative and early postoperative outcomes of Descemet stripping automated endothelial keratoplasty (DSAEK) in patients with previous glaucoma filtering surgeries...
  68. ncbi Malignant glaucoma following needling of a trabeculectomy bleb
    R Mathur
    Eye (Lond) 16:667-8. 2002
  69. ncbi Combined surgery in the treatment of patients with cataract and primary open-angle glaucoma
    R J Casson
    Oxford Eye Hospital, United Kingdom, Oxford, UK
    J Cataract Refract Surg 27:1854-63. 2001
    ..and reduced the complication rate previously associated with extracapsular cataract extraction combined with trabeculectomy. A mean reduction in intraocular pressure (IOP) of 5 to 8 mm Hg can be achieved...
  70. ncbi Phacoemulsification with intraocular lens implantation after trabeculectomy
    R Casson
    Nuffield Laboratory of Ophthalmology, Oxford University, England
    J Glaucoma 11:429-33. 2002
    To determine the effect of phacoemulsification with intraocular lens (IOL) implantation, using a superior clear-corneal incision, on the long-term intraocular pressure (IOP) control in patients who have undergone previous trabeculectomy.
  71. ncbi A comparison of the intervisit intraocular pressure fluctuation after 180 and 360 degrees of selective laser trabeculoplasty (SLT) as a primary therapy in primary open angle glaucoma and ocular hypertension
    Navin Prasad
    Massachusetts Eye and Ear Infirmary, Boston, MA, USA
    J Glaucoma 18:157-60. 2009
    ....
  72. ncbi The National Survey of Trabeculectomy. III. Early and late complications
    B Edmunds
    Royal College of Ophthalmologists, London, UK
    Eye (Lond) 16:297-303. 2002
    There is a considerable body of literature relating to trabeculectomy, however there are no data representative of the national experience of trabeculectomy in the United Kingdom (UK)...
  73. ncbi Recent advances in trabeculectomy technique
    Emma Jones
    ORB Ocular Repair and Regeneration Biology, Divisions of Pathology and Glaucoma, Institute of Ophthalmology and Moorfields Eye Hospital, London, UK
    Curr Opin Ophthalmol 16:107-13. 2005
    b>Trabeculectomy is an effective operation for lowering intraocular pressure. However, success is limited by complications such as infection, hypotony, and scarring.
  74. pmc Selective laser trabeculoplasty versus argon laser trabeculoplasty: results from a 1-year randomised clinical trial
    K F Damji
    University of Ottawa Eye Institute, Ottawa, Ontario, Canada
    Br J Ophthalmol 90:1490-4. 2006
    ..To compare selective laser trabeculoplasty (SLT) and argon laser trabeculoplasty (ALT), in terms of intraocular pressure (IOP) lowering, in patients with open-angle glaucoma...
  75. ncbi Bleb-associated endophthalmitis: clinical characteristics and visual outcomes
    Brandon G Busbee
    Retina Service, New England Eye Center, Boston, USA
    Ophthalmology 111:1495-503; discussion 1503. 2004
    ..To analyze the clinical characteristics and treatment outcomes of patients with bleb-associated endophthalmitis (BAE)...
  76. pmc Baseline IOP predicts selective laser trabeculoplasty success at 1 year post-treatment: results from a randomised clinical trial
    W G Hodge
    Department of Ophthalmology, The University of Ottawa Eye Institute, 501 Smyth Road, Ottawa, ON K1H 8L6 Canada
    Br J Ophthalmol 89:1157-60. 2005
    ..This study's objective is to determine factors that predict successful SLT at 1 year post-treatment...
  77. ncbi Trabeculectomy with mitomycin C combined with direct cauterization of peripheral iris in the management of neovascular glaucoma
    Ufuk Elgin
    Ankara Ulucanlar Eye Research Hospital, Ankara, Turkey
    J Glaucoma 15:466-70. 2006
    To determine the outcomes of trabeculectomy with mitomycin C (MMC) combined with direct cauterization of peripheral iris before iridectomy in the management of neovascular glaucoma (NVG), and to demonstrate the effect of this surgical ..
  78. ncbi The management of post-keratoplasty glaucoma by trabeculectomy
    A M Gilvarry
    Corneal Clinic, Moorfields Eye Hospital, London
    Eye (Lond) 3:713-8. 1989
    ..Five eyes remained phakic until trabeculectomy was performed...
  79. ncbi Update on antifibrotic use in glaucoma surgery, including use in trabeculectomy and glaucoma drainage implants and combined cataract and glaucoma surgery
    Patricia S Yoon
    Stanford University, School of Medicine, Stanford, California, USA
    Curr Opin Ophthalmol 15:141-6. 2004
    ..This paper summarizes the use of antifibrotic agents adjunctive to glaucoma surgery, reviews recently published studies that address current use of these antifibrotics, and reviews new methods of wound modulation...
  80. ncbi Phacotrabeculectomy with mitomycin C in patients with uveitis
    Un Chul Park
    Department of Ophthalmology, Seoul National University College of Medicine, Seoul, Korea
    Am J Ophthalmol 142:1005-12. 2006
    To evaluate the safety and efficacy of combined phacoemulsification, intraocular lens implantation, and trabeculectomy with mitomycin C for the management of uveitic complications.
  81. ncbi Three-year follow-up of the tube versus trabeculectomy study
    Steven J Gedde
    Bascom Palmer Eye Institute, Miller School of Medicine, University of Miami, Miami, FL 33136, USA
    Am J Ophthalmol 148:670-84. 2009
    To report 3-year results of the Tube Versus Trabeculectomy (TVT) Study.
  82. ncbi Long-term outcomes of repeat vs initial trabeculectomy in open-angle glaucoma
    Simon K Law
    Glaucoma Division, Jules Stein Eye Institute, David Geffen School of Medicine, UCLA, Los Angeles, CA 90095, USA
    Am J Ophthalmol 148:685-695.e1. 2009
    To evaluate the long-term intraocular pressure (IOP) control and to identify risk factors for failure of repeat trabeculectomy with mitomycin C (MMC) in patients with open-angle glaucoma.
  83. ncbi Long-term effects of simultaneous subconjunctival and subscleral mitomycin C application in repeat trabeculectomy
    Yi An You
    Department of Ophthalmology, First Affiliated Hospital, Wenzhou Medical College, Wenzhou, Zhejiang, China
    J Glaucoma 11:110-8. 2002
    To assess the efficacy and safety of simultaneous mitomycin C application under conjunctival and scleral flaps in patients with repeat trabeculectomy.
  84. ncbi Viscocanalostomy versus trabeculectomy for primary open angle glaucoma: 4-year prospective randomized clinical trial
    D F Gilmour
    Department of Ophthalmology, St James s University Hospital, Leeds, UK
    Eye (Lond) 23:1802-7. 2009
    The purpose of this randomized clinical trial was to compare the effectiveness and safety of viscocanalostomy (visco) with trabeculectomy (trab) in the management of primary open angle glaucoma (POAG).
  85. ncbi Five-year results of trabeculectomy with mitomycin C
    Henny J M Beckers
    University Eye Clinic, Academic Hospital Maastricht, P O Box 5800, 6202 AZ, Maastricht, The Netherlands
    Graefes Arch Clin Exp Ophthalmol 241:106-10. 2003
    The long-term efficacy and safety of primary trabeculectomy with mitomycin C were retrospectively studied.
  86. pmc Visual field progression in the Collaborative Initial Glaucoma Treatment Study the impact of treatment and other baseline factors
    David C Musch
    Department of Ophthalmology and Visual Sciences, The University of Michigan, Ann Arbor, Michigan 48105, USA
    Ophthalmology 116:200-7. 2009
    ..To evaluate factors associated with visual field (VF) progression, using all available follow-up through 9 years after treatment initiation, in the Collaborative Initial Glaucoma Treatment Study (CIGTS)...
  87. ncbi Imaging of trabeculectomy blebs using anterior segment optical coherence tomography
    Mandeep Singh
    National University Hospital, Singapore
    Ophthalmology 114:47-53. 2007
    To image trabeculectomy blebs using anterior segment optical coherence tomography (AS-OCT).
  88. ncbi Selective laser trabeculoplasty as initial and adjunctive treatment for open-angle glaucoma
    Ian McIlraith
    Ivey Eye Institute, University of Western Ontario, London, Ontario, Canada
    J Glaucoma 15:124-30. 2006
    ..To investigate the efficacy and safety of selective laser trabeculoplasty as an initial treatment for newly diagnosed open-angle glaucoma, and its role as adjunctive therapy...
  89. pmc Clinical results with the Trabectome, a novel surgical device for treatment of open-angle glaucoma
    Don Minckler
    University of Southern California Keck School of Medicine, Los Angeles, California, USA
    Trans Am Ophthalmol Soc 104:40-50. 2006
    ..To describe treatment outcomes after Trabectome surgery in an initial series of 101 patients with open-angle glaucoma...
  90. ncbi Efficacy and safety of mitomycin-C in primary trabeculectomy: five-year follow-up
    Rajiv Bindlish
    Department of Ophthalmology, Allegheny General Hospital, 420 East North Avenue, Pittsburgh, PA 15212, USA
    Ophthalmology 109:1336-41; discussion 1341-2. 2002
    To examine the 5-year complications and results of primary trabeculectomy with mitomycin-C (MMC).
  91. pmc A randomised, prospective study comparing selective laser trabeculoplasty with latanoprost for the control of intraocular pressure in ocular hypertension and open angle glaucoma
    M Nagar
    Department of Ophthalmology, St Thomas s Hospital, Lambeth Palace Road, London SE1 7EH, UK
    Br J Ophthalmol 89:1413-7. 2005
    ..005% for the control of intraocular pressure (IOP) in ocular hypertension (OHT) and open angle glaucoma (OAG)...
  92. ncbi Trabeculectomy with intraoperative 5-fluorouracil vs mitomycin C
    K Singh
    Department of Ophthalmology, Stanford University Medical Center, CA 94305 5308, USA
    Am J Ophthalmol 123:48-53. 1997
    To compare the effectiveness of intraoperative 5-fluorouracil (5-FU) and mitomycin C used adjunctively with trabeculectomy in a black West African population.
  93. ncbi Selective laser trabeculoplasty as primary treatment for open-angle glaucoma: a prospective, nonrandomized pilot study
    Shlomo Melamed
    The Sam Rothberg Glaucoma Center, Goldschleger Eye Institute, Sheba Medical Center, Tel Hashomer, Israel
    Arch Ophthalmol 121:957-60. 2003
    ..To examine the safety and efficacy of selective laser trabeculoplasty as primary treatment for patients with open-angle glaucoma...
  94. ncbi A prospective randomized trial comparing intraoperative 5-fluorouracil vs mitomycin C in primary trabeculectomy
    Darrell WuDunn
    Department of Ophthalmology, Indiana University, Indianapolis 46202, USA
    Am J Ophthalmol 134:521-8. 2002
    To compare the safety and efficacy of intraoperative 5-fluorouracil (5-FU) or Intraoperative mitomycin C (MMC) in eyes undergoing primary trabeculectomy.
  95. ncbi Long-term comparison of primary trabeculectomy with 5-fluorouracil versus mitomycin C in West Africa
    Hanna Y Kim
    Department of Ophthalmology, Stanford University School of Medicine, Stanford, CA 97303, USA
    J Glaucoma 17:578-83. 2008
    To compare the long-term efficacy and safety of intraoperative 5-fluorouracil (5-FU) versus mitomycin-C (MMC) used adjunctively with primary trabeculectomy in a Black West African population.
  96. ncbi Intraocular pressure response to selective laser trabeculoplasty in the treatment of primary open-angle glaucoma
    T Gracner
    Department of Ophthalmology, General Hospital Maribor, Slovenia
    Ophthalmologica 215:267-70. 2001
    ..66 mm Hg (SD 2.40) or 25.2%; at the end of 6 months of follow-up, IOP was reduced with a mean of 5.06 mm Hg (SD 2.37) or 22.5%. CONCLUSIONS: SLT is an effective method for lowering IOP in the treatment of POAG...
  97. pmc Selective laser trabeculoplasty: predictive value of early intraocular pressure measurements for success at 3 months
    P B Johnson
    Massachusetts Eye and Ear Infirmary, 243 Charles Street, Boston, MA 02114, USA
    Br J Ophthalmol 90:741-3. 2006
    ..To determine the predictive value of the 2 week post-selective laser trabeculoplasty (SLT) intraocular pressure (IOP) by comparing it to the 4 week and 3 month values...
  98. ncbi Effects of octreotide acetate and amniotic membrane on wound healing in experimental glaucoma surgery
    Tamer Demir
    Department of Ophthalmology, Firat University Medical School, Elazig, Turkey
    Doc Ophthalmol 107:87-92. 2003
    ..Thirty pigmented rabbits were divided into three groups each including 10 animals. Trabeculectomy and topical postoperative prednisolone sodium phosphate four times daily for 7 days were applied to one eye of ..
  99. ncbi Trabeculectomy with and without mitomycin-C in a black African population
    J C Mwanza
    Department of Ophthalmology, University Hospital of Kinshasa, Democratic Republic of Congo
    Eur J Ophthalmol 11:261-3. 2001
    To evaluate the beneficial effects of intraoperative application of mitomycin-C during trabeculectomy in a black African population in Congo-Kinshasa.
  100. ncbi Needle elevation of the scleral flap for failing filtration blebs after trabeculectomy with mitomycin C
    D S Greenfield
    Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami School of Medicine, Florida, USA
    Am J Ophthalmol 122:195-204. 1996
    To report the incidence of failing filtration blebs after trabeculectomy with mitomycin C and to report the outcome of needling procedures for failing filtration blebs in these eyes.
  101. ncbi Cystic bleb formation and related complications in limbus- versus fornix-based conjunctival flaps in pediatric and young adult trabeculectomy with mitomycin C
    Anthony P Wells
    Wound Healing Research Unit and Glaucoma Unit, Institute of Ophthalmology and Moorfields Eye Hospital, London, United Kingdom
    Ophthalmology 110:2192-7. 2003
    Comparison of fornix- and limbus-based conjunctival flaps with respect to cystic bleb-related complications of trabeculectomy with high-dose mitomycin C (MMC) in pediatric and young adult glaucoma.

Research Grants55

  1. Suppression of Ocular Scarring - Controlled Delivery of an ALK-5 Inhibitor
    Hiroshi Nakamura; Fiscal Year: 2013
    ..trial, there was no difference between the antibody and a placebo in preventing the failure of primary trabeculectomy in human glaucoma eyes. In addition, clinical usage of antisense/siRNAs is still questionable...
  2. Smad3 inhibitors for ophthalmic applications
    Ching Yuan; Fiscal Year: 2010
    ..The fibrosis and neovascularization by alkaline burn, mechanical debridement and trabeculectomy surgery will be conducted on rabbit cornea and conjunctiva for the evaluation of Smad3 inhibitors...
  3. FLUOROURACIL FILTERING SURGERY STUDY
    WALLACE ALWARD; Fiscal Year: 1992
    ..glaucoma after previous cataract extraction or unsuccessful filtering surgery, or both, were randomized to a trabeculectomy alone (standard treatment), or to trabeculectomy with adjunctive 5-FU injections...
  4. 5-FLUOROURACIL & GLAUCOMA FILTERING SURGERY
    Dale Heuer; Fiscal Year: 1992
    ..glaucoma after previous cataract extraction or unsuccessful filtering surgery, or both, were randomized to a trabeculectomy alone (standard treatment), or to trabeculectomy with adjunctive 5-FU injections...
  5. 5-FLUOROURACIL & GLAUCOMA FILTERING SURGERY
    Richard Parrish; Fiscal Year: 1993
    ..after previous cataract extraction or unsuccessful filtering surgery, or both, were randomized to undergo trabeculectomy alone (standard treatment) or trabeculectomy with adjunctive 5-FU injections...
  6. 5-FLUOROURACIL AND GLAUCOMA FILTERING SURGERY
    MICHAEL KASS; Fiscal Year: 1992
    ..glaucoma after previous cataract extraction or unsuccessful filtering surgery, or both, were randomized to a trabeculectomy alone (standard treatment), or to trabeculectomy with adjunctive 5-FU injections...
  7. Pulsed Electron Avalanche Knife: Intraocular Microsurg.
    Daniel Palanker; Fiscal Year: 2006
    ..Applications to non-penetrating trabeculectomy and other ophthalmic and non-ophthalmic microsurgical procedures will be explored...
  8. PERIOPERATIVE WOUND LEAKS AFTER TRABECULECTOMY IN FFSS
    Richard Parrish; Fiscal Year: 1999
    ..The FFSS was an NEI-sponsored, multicenter, randomized clinical trial to compare the results of trabeculectomy with and without postoperative, subconjunctival injections of 5-fluorouracil (5-FU), in patients with poor ..
  9. DEVELOPMENT OF A NOVEL GLAUCOMA IMPLANT
    Abdul Ahmed; Fiscal Year: 2004
    ..Current surgical options for refractory glaucoma include trabeculectomy and the use of glaucoma drainage implants...
  10. Amniotic Membrane Patch Graft to Cover Glaucoma Drainage Tube
    HOSAM EL SHEHA; Fiscal Year: 2009
    ..will allow us in Phase II investigate whether it can also be considered as a graft to augment the success of trabeculectomy with mitomycin C in high risk refractory glaucoma...
  11. Trabecular Bypass Stent and Applicator
    GREGORY SMEDLEY; Fiscal Year: 2002
    ..After failure of conservative therapy, trabeculectomy with or without antimetabolites is used to lower lop...
  12. Development of a micropump for the glaucomatous eye
    DAVID HAFFNER; Fiscal Year: 2005
    ..After failure of conservative therapy, trabeculectomy with or without antimetabolites is used to lower IOP...
  13. ADVANCED GLAUCOMA INTERVENTION STUDY
    Allen Beck; Fiscal Year: 2000
    ..Each eye has been randomly assigned to one of two intervention sequences: 1) trabeculectomy (T) followed by argon laser trabeculoplasty (ALT) should T fail and followed by a second T should the ALT fail;..
  14. ADVANCED GLAUCOMA INTERVENTION STUDY
    Jacob Wilensky; Fiscal Year: 2000
    ..Each eye has been randomly assigned to one of two intervention sequences: 1) trabeculectomy (T) followed by argon laser trabeculoplasty (ALT) should T fail and followed by a second T should ALT fail; ..
  15. ADVANCED GLAUCOMA INTERVENTION STUDY (AGIS)
    Robert Allen; Fiscal Year: 2000
    ..Each eye has been randomly assigned to one of two intervention sequences: 1) trabeculectomy (T) followed by argon laser trabeculoplasty (ALT) should T fail and followed by a second T should ALT fail; ..
  16. ADVANCED GLAUCOMA INTERVENTION STUDY
    Douglas Gaasterland; Fiscal Year: 2001
    ..Each eye has been randomly assigned to one of two intervention sequences: 1) trabeculectomy (T) followed by argon laser trabeculoplasty (ALT) should T fall and followed by a second T should ALT fail; ..
  17. ADVANCED GLAUCOMA INTERVENTION STUDY
    M Shields; Fiscal Year: 2000
    ..Each eye has been randomly assigned to one of two intervention sequences: 1) trabeculectomy (T) followed by argon laser trabeculoplasty (ALT) should T fail and followed by a second T should ALT fail; ..
  18. AGIS CONTINUATION PIEDMONT HOSPITAL
    M Vela; Fiscal Year: 2000
    ..Each eye has been randomly assigned to one of two intervention sequences: 1) trabeculectomy (T) followed by argon laser trabeculoplasty (ALT) should T fail and followed by a second T should ALT fail; ..
  19. ADVANCED GLAUCOMA INTERVENTION STUDY
    Paul Weber; Fiscal Year: 2000
    ..Each eye has been randomly assigned to one of two intervention sequences: 1) trabeculectomy (T) followed by argon laser trabeculoplasty (ALT) should T fail and followed by a second T should the ALT fail;..
  20. ADVANCED GLAUCOMA INTERVENTION STUDY
    PAUL LICHTER; Fiscal Year: 2000
    ..Each eye has been randomly assigned to one of two intervention sequences: i) trabeculectomy (T) followed by argon Laser trabeculoplasty (ALT) should T fail and followed by a second T should ALT fait; ..
  21. LASER TRABECULAR ABLATION
    JAMES HSIA; Fiscal Year: 1991
    ....
  22. Proteomic Analyses of Human Trabecular Meshwork
    Sanjoy Bhattacharya; Fiscal Year: 2007
    ..Proteomic analyses of TM tissue from in vivo trabeculectomy and left over rim-tissue from cornea transplant will be pursued to determine protein differences between ..
  23. ADVANCED GLAUCOMA INTERVENTION STUDY
    Jay Katz; Fiscal Year: 2000
    ..Each eye has been randomly assigned to one of two intervention sequences: 1) trabeculectomy (T) followed by argon laser trabeculoplasty (ALT) should T fail and followed by a second T should ALT fail; ..
  24. ADVANCED GLAUCOMA INTERVENTION STUDY COORDINATING CENTER
    PAUL VAN VELDHUISEN; Fiscal Year: 2002
    ..Each eye has been randomly assigned to one of two intervention sequences: 1) trabeculectomy (T) followed by argon laser trabeculoplasty (ALT) should T fail and followed by a second T should ALT fail; ..
  25. AGIS CLINIC WHC ADVANCED GLAUCOMA INTERVENTION STUDY
    Arthur Schwartz; Fiscal Year: 2001
    ..Each eye has been randomly assigned to one of two intervention sequences: 1) trabeculectomy (T) followed by argon laser trabeculoplasty (ALT) should T fail and followed by a second T should ALT fail; ..
  26. ADVANCED GLAUCOMA INTERVENTION STUDY
    MARSHALL CYRLIN; Fiscal Year: 2000
    ..Each eye has been randomly assigned to one of two intervention sequences: 1) trabeculectomy (T) followed by argon laser trabeculoplasty (ALT) should T fail and followed by a second T should ALT fail; ..
  27. Portable fiber laser for glaucoma surgery
    KURT LINDEN; Fiscal Year: 2003
    ..will be designed and fabricated, and a comparison will be made between laser sclerectomy and conventional trabeculectomy, using rabbit models. Effects on outflow facility will be evaluated using LTA in cadaver human eyes...
  28. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Allen Beck; Fiscal Year: 2008
    ..This application includes information on Dr. Brown and his two co-investigators who will follow patients screened for enrollment and randomization to treatment in the OHTS clinical trial." ..
  29. OCULAR HYPERTENSION TREATMENT STUDY (OHTS)
    Donald Budenz; Fiscal Year: 2008
    ....
  30. COLLABORATIVE INITIAL GLAUCOMA TREATMENT STUDY
    Philip Chen; Fiscal Year: 2002
    ....
  31. DATA COORDINATING CENTER FOR EARLY GLAUCOMA TRIAL
    M Leske; Fiscal Year: 2004
    ....
  32. EARLY DETECTION OF GLAUCOMA DAMAGE
    Henry Jampel; Fiscal Year: 2004
    ..This assessment of the RTA and NFA will help to establish their utility as outcome measures for clinical management of glaucoma, epidemiological research, and clinical trials. ..
  33. GLAUCOMA SURGICAL OUTCOMES STUDY
    Henry Jampel; Fiscal Year: 2001
    ..The results of the study may allow physicians to reduce the morbidity of glaucoma surgery by altering their indications for surgery, surgical technique, and postoperative follow-up. ..
  34. NEUROTROPHIC FACTOR MODULATION OF CORNEAL ENDOTHELIUM
    Shay Whey Koh; Fiscal Year: 2009
    ..abstract_text> ..
  35. EARLY MANIFEST GLAUCOMA TRIAL
    Anders Heijl; Fiscal Year: 2004
    ..It is expected, that the large scale community screening effort to recruit study participants with as yet undetected glaucoma, will require screening of 20,000 to 30,000 Malmo citizens in appropriate age groups. ..
  36. COLLABORATIVE INITIAL GLAUCOMA TREATMENT STUDY
    Henry Jampel; Fiscal Year: 2002
    ....
  37. PREVALENCE AND IMPACT OF GLAUCOMA AMONG THE VERY ELDERLY
    David Friedman; Fiscal Year: 2003
    ..Finally, the interactions between comorbidities (including cognitive deficits) and visual field loss will be explored. ..
  38. Quan11tification of Glaucomatous Optic Neuropathy
    Christopher Girkin; Fiscal Year: 2006
    ....
  39. CIGTS-2 Optic Disc Reading Center
    Richard Parrish; Fiscal Year: 2005
    ..To provide the Coordinating Center with optic disc progression rates ..
  40. Analysis of CIGTS Visual Field Data
    David Musch; Fiscal Year: 2005
    ..3. Determine the relative impact of factors other than IOP control and race on progressive VF loss. Address age, sex, family history, comorbidities, smoking, alcohol ingestion, refractive error, and baseline VF damage. ..
  41. Genetic Studies of Pseudoexfoliation Glaucoma
    Janey Wiggs; Fiscal Year: 2004
    ....
  42. CELLULAR BIOLOGY OF THE TRABECULAR MESHWORK
    Michael P Fautsch; Fiscal Year: 2010
    ..These regions will be "preferential flow" regions, and aqueous tracers should appear in these regions first. If this occurs, it would change our basic understanding of how aqueous passes through the TM (aim 5). ..
  43. COLLABORATIVE STUDY OF INITIAL GLAUCOMA TREATMENT
    PAUL LICHTER; Fiscal Year: 2003
    ....
  44. Genetic Etiologies of Primary Open Angle Glaucoma
    Janey Wiggs; Fiscal Year: 2009
    ..Specific genetic defects will be correlated with clinical phenotype by investigating familial aggregation of clinical parameters and looking for evidence of gene/gene interactions and how these interactions may influence phenotype. ..
  45. Gene Delivery to the Trabecular Meshwork
    Douglas Rhee; Fiscal Year: 2004
    ..These studies would set the foundation for future evaluations of the function of MIF in the TM and MIF?s potential as a candidate for gene therapy for the treatment of glaucoma. ..
  46. Transcriptional silencing in damaged retinal ganglia
    Robert Nickells; Fiscal Year: 2004
    ....
  47. The Role of Outer Retinal Injury in Glaucoma
    T Nork; Fiscal Year: 2004
    ..abstract_text> ..
  48. Molecular Analysis of the Human Aqueous Outflow Pathway
    Michael P Fautsch; Fiscal Year: 2010
    ..We will also determine gene and protein expression changes in the meshwork induced by normal and POAG aqueous humor. Develop a medium that can be used to mimic aqueous humor for trabecular meshwork cell culture. ..
  49. PATHOGENESIS OF GLAUCOMATOUS OPTIC NERVE DAMAGE
    Harry Quigley; Fiscal Year: 2008
    ..Candidate molecules for genetic susceptibility to glaucoma are likely to be identified. ..
  50. FAMILIAL PRIMARY OPEN ANGLE GLAUCOMA
    Janey Wiggs; Fiscal Year: 2004
    ..Initial genome screens to identify genes responsible for two POAG risk factors, ocular hypertension (OHT) and pseudoexfoliation (PEX), will be performed. ..
  51. LINKAGE STUDY OF JUVENILE GLAUCOMA
    Janey Wiggs; Fiscal Year: 2008
    ..3) Screen candidate genes located in the RIEG2 region on chromosome 13q14. 4) Correlate mutations in genes known to cause glaucoma with clinical phenotypes. ..
  52. Mapping RGC susceptibility alleles
    Robert Nickells; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  53. ELECTRON MICROSCOPIC STUDIES OF CRYSTALLINE LENSES
    Jer Kuszak; Fiscal Year: 2006
    ..cataracts that arise in the long term (>50% of all older patients) as a complication of vitrectomy or trabeculectomy in an established animal model; 2) to characterize, for the first time, the relationship between lens sutures ..
  54. Molecular Phenotypes of Primary Open Angle Glaucoma
    Mary K Wirtz; Fiscal Year: 2010
    ..This study will form the basis for future studies aimed at identifying and characterizing the genes that influence POAG risk factors. ..