nerve transfer

Summary

Summary: Surgical reinnervation of a denervated peripheral target using a healthy donor nerve and/or its proximal stump. The direct connection is usually made to a healthy postlesional distal portion of a non-functioning nerve or implanted directly into denervated muscle or insensitive skin. Nerve sprouts will grow from the transferred nerve into the denervated elements and establish contact between them and the neurons that formerly controlled another area.

Top Publications

  1. ncbi Gracilis free muscle transfer for restoration of function after complete brachial plexus avulsion
    Kimberly A Barrie
    Triangle Orthopaedic Associates, Durham, North Carolina, USA
    Neurosurg Focus 16:E8. 2004
  2. ncbi Peripheral nerve injury evaluation and management
    Christopher J Winfree
    Department of Neurological Surgery, Columbia University Medical Center, New York, NY, USA
    Curr Surg 62:469-76. 2005
  3. ncbi Motor recovery and the breathing arm after brachial plexus surgical repairs, including re-implantation of avulsed spinal roots into the spinal cord
    M Htut
    Peripheral Nerve Injury Unit, Royal National Orthopaedic Hospital, Stanmore, UK
    J Hand Surg Eur Vol 32:170-8. 2007
  4. ncbi Methylcobalamin, but not methylprednisolone or pleiotrophin, accelerates the recovery of rat biceps after ulnar to musculocutaneous nerve transfer
    W C Liao
    Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan
    Neuroscience 171:934-49. 2010
  5. pmc Restoration of contralateral representation in the mouse somatosensory cortex after crossing nerve transfer
    Haruyoshi Yamashita
    Department of Neurophysiology, Brain Research Institute, Niigata University, Niigata, Japan
    PLoS ONE 7:e35676. 2012
  6. ncbi Nerve transfer to deltoid muscle using the nerve to the long head of the triceps, part II: a report of 7 cases
    Somsak Leechavengvongs
    Upper Extremity and Reconstructive Microsurgery Unit, Institute of Orthopaedics, Lerdsin General Hospital, Bangkok, Thailand
    J Hand Surg Am 28:633-8. 2003
  7. ncbi Nerve transfers for brachial plexus reconstruction
    Stephen H Colbert
    Division of Plastic Surgery, University of Missouri School of Medicine, One Hospital Drive, M349, Columbia, MO 65212, USA
    Hand Clin 24:341-61, v. 2008
  8. ncbi Peripheral nerve injury: a review and approach to tissue engineered constructs
    G R Evans
    Division of Plastic Surgery, The University of California, Irvine, Orange, CA 92868, USA
    Anat Rec 263:396-404. 2001
  9. ncbi Hemihypoglossal nerve transfer in brachial plexus repair: technique and results
    Stefano Ferraresi
    Department of Neurosurgery and Neurology, Ospedale S Maria della Misericordia, Rovigo, Italy
    Neurosurgery 50:332-5. 2002
  10. ncbi Phrenic nerve transfer for elbow flexion and intercostal nerve transfer for elbow extension
    Mou Xiong Zheng
    Department of Hand Surgery, Hua Shan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
    J Hand Surg Am 35:1304-9. 2010

Research Grants

  1. URINARY BLADDER MUSCARINIC RECEPTOR SUBTYPES
    MICHAEL RUGGIERI; Fiscal Year: 2003
  2. Role of Endogenous Opioid System in the Placebo Effect
    James Campbell; Fiscal Year: 2006
  3. A role for dopamine in brain development
    Pradeep Bhide; Fiscal Year: 2007
  4. MECHANISMS OF NEUROPATHIC PAIN
    James Campbell; Fiscal Year: 2008
  5. HYPOTHERMIA FOR SEVERE TBI IN CHILDREN
    P David Adelson; Fiscal Year: 2004
  6. COCAINE AND BRAIN DEVELOPMENT
    Pradeep G Bhide; Fiscal Year: 2010
  7. Surgical Management of Facial Nerve Injury
    Theresa Hadlock; Fiscal Year: 2007

Detail Information

Publications176 found, 100 shown here

  1. ncbi Gracilis free muscle transfer for restoration of function after complete brachial plexus avulsion
    Kimberly A Barrie
    Triangle Orthopaedic Associates, Durham, North Carolina, USA
    Neurosurg Focus 16:E8. 2004
    ..The authors report the functional outcomes after functioning free muscle transfer (FFMT) for restoration of the upper-extremity movement after brachial plexus injury (BPI)...
  2. ncbi Peripheral nerve injury evaluation and management
    Christopher J Winfree
    Department of Neurological Surgery, Columbia University Medical Center, New York, NY, USA
    Curr Surg 62:469-76. 2005
  3. ncbi Motor recovery and the breathing arm after brachial plexus surgical repairs, including re-implantation of avulsed spinal roots into the spinal cord
    M Htut
    Peripheral Nerve Injury Unit, Royal National Orthopaedic Hospital, Stanmore, UK
    J Hand Surg Eur Vol 32:170-8. 2007
    ..Our study shows that re-connection of avulsed spinal roots can produce good motor recovery and provides a clinical model for developing new treatments which may enhance nerve regeneration...
  4. ncbi Methylcobalamin, but not methylprednisolone or pleiotrophin, accelerates the recovery of rat biceps after ulnar to musculocutaneous nerve transfer
    W C Liao
    Institute of Anatomy and Cell Biology, College of Medicine, National Taiwan University, Taipei, Taiwan
    Neuroscience 171:934-49. 2010
    ..In conclusion, methylcobalamin may be preferred over methylprednisolone to facilitate the recovery of peripheral nerves following end-to-end neurorrhaphy. The long-term effect of this treatment however remains to be clarified...
  5. pmc Restoration of contralateral representation in the mouse somatosensory cortex after crossing nerve transfer
    Haruyoshi Yamashita
    Department of Neurophysiology, Brain Research Institute, Niigata University, Niigata, Japan
    PLoS ONE 7:e35676. 2012
    Avulsion of spinal nerve roots in the brachial plexus (BP) can be repaired by crossing nerve transfer via a nerve graft to connect injured nerve ends to the BP contralateral to the lesioned side...
  6. ncbi Nerve transfer to deltoid muscle using the nerve to the long head of the triceps, part II: a report of 7 cases
    Somsak Leechavengvongs
    Upper Extremity and Reconstructive Microsurgery Unit, Institute of Orthopaedics, Lerdsin General Hospital, Bangkok, Thailand
    J Hand Surg Am 28:633-8. 2003
    This study reports the results of nerve transfer to the deltoid muscle using the nerve to the long head of the triceps.
  7. ncbi Nerve transfers for brachial plexus reconstruction
    Stephen H Colbert
    Division of Plastic Surgery, University of Missouri School of Medicine, One Hospital Drive, M349, Columbia, MO 65212, USA
    Hand Clin 24:341-61, v. 2008
    ..The authors present a review of current surgical options for treatment of partial and complete adult brachial plexus injuries using nerve transfers...
  8. ncbi Peripheral nerve injury: a review and approach to tissue engineered constructs
    G R Evans
    Division of Plastic Surgery, The University of California, Irvine, Orange, CA 92868, USA
    Anat Rec 263:396-404. 2001
    ..This impotency rate decreased to 24% when the nerves were left intact (Quinlan et al., J. Urol. 1991;145:380-383; J. Urol. 1991;145:998-1002)...
  9. ncbi Hemihypoglossal nerve transfer in brachial plexus repair: technique and results
    Stefano Ferraresi
    Department of Neurosurgery and Neurology, Ospedale S Maria della Misericordia, Rovigo, Italy
    Neurosurgery 50:332-5. 2002
    ..We explored the possibility of using the hypoglossal nerve as a transfer point to reanimate muscles in the upper limb...
  10. ncbi Phrenic nerve transfer for elbow flexion and intercostal nerve transfer for elbow extension
    Mou Xiong Zheng
    Department of Hand Surgery, Hua Shan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
    J Hand Surg Am 35:1304-9. 2010
    ..To explore long-term recovery of elbow flexion and extension after transferring the phrenic nerve and intercostal nerves, respectively, in adults with global brachial plexus avulsion injuries...
  11. ncbi Intercostal nerve transfer in infants with obstetric brachial plexus palsy
    Tarek A El-Gammal
    Reconstructive Microsurgery Unit, Assiut University Hospitals and School of Medicine, Assiut, Egypt
    Microsurgery 28:499-504. 2008
    ..We conclude that, intercostals nerve transfer is an effective procedure for restoration of function in infants with OBPP and root avulsions...
  12. ncbi Initial report on the limited value of hypoglossal nerve transfer to treat brachial plexus root avulsions
    M J Malessy
    Department of Neurosurgery, Leiden University Medical Center, The Netherlands
    J Neurosurg 91:601-4. 1999
    ..Hypoglossal nerve (12th cranial nerve) transfer was performed to treat the sequelae of brachial plexus root avulsion in 12 adults and two infants, and the patients were followed to assess the effectiveness of the surgery...
  13. ncbi The "babysitter" procedure: minihypoglossal to facial nerve transfer and cross-facial nerve grafting
    Julia K Terzis
    Department of Surgery, Division of Plastic and Reconstructive Surgery, and Microsurgical Program, Microsurgical Research Center, Eastern Virginia Medical School, Norfolk, VA 23501, USA
    Plast Reconstr Surg 123:865-76. 2009
    ..This article presents the senior author's (J.K.T.) experience with the original procedure...
  14. ncbi Nerve transfers in brachial plexus birth palsies: indications, techniques, and outcomes
    Scott H Kozin
    Department of Orthopaedic Surgery, Temple University, 3401 Broad Street, Philadelphia, PA 19140, USA
    Hand Clin 24:363-76, v. 2008
    ..Time will tell the ultimate role of nerve transfer or nerve grafting.
  15. ncbi The intercostal to phrenic nerve transfer: an effective means of reanimating the diaphragm in patients with high cervical spine injury
    L M Krieger
    Department of Surgery, UCLA Medical Center, Los Angeles, Calif 90095, USA
    Plast Reconstr Surg 105:1255-61. 2000
    ..Intercostal to phrenic nerve transfer with diaphragmatic pacing is a viable means of liberating patients with high cervical spine injury from long-..
  16. ncbi Suprascapular nerve reconstruction in obstetrical brachial plexus palsy: spinal accessory nerve transfer versus C5 root grafting
    Raymond Tse
    Division of Plastic Surgery, Hospital for Sick Children, Department of Surgery, University of Toronto, Toronto, Ontario, Canada
    Plast Reconstr Surg 127:2391-6. 2011
    ..of this study was to determine whether there is any difference in external rotation following reconstruction of the suprascapular nerve using nerve grafts from the proximal C5 root or nerve transfer using the spinal accessory nerve.
  17. pmc Supercharge nerve transfer to enhance motor recovery: a laboratory study
    Scott J Farber
    Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Hand Surg Am 38:466-77. 2013
    To investigate the ability of a supercharge end-to-side (SETS) nerve transfer to augment the effect of regenerating native axons in an incomplete rodent sciatic nerve injury model.
  18. ncbi Ulnar nerve to musculocutaneous nerve transfer in an ulnar ray-deficient infant with brachial plexus birth palsy: case report
    M M Al-Qattan
    Division of Plastic Surgery and Department of Anesthesia and Intensive Care, King Saud University, Riyadh, Saudi Arabia
    J Hand Surg Am 35:1432-4. 2010
    In Oberlin's nerve transfer, a fascicle of the ulnar nerve is sutured end-to-end to the branch of musculocutaneous nerve to the biceps muscle in the arm...
  19. ncbi Restoration of shoulder abduction in brachial plexus injury with phrenic nerve transfer
    A Sungpet
    Department of Orthopedics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Aust N Z J Surg 70:783-5. 2000
    ..In the literature there are few reports on phrenic nerve transfer, especially in relation to restoration of shoulder function...
  20. ncbi Nerve transfer for treatment of brachial plexus injury: comparison study between the transfer of partial median and ulnar nerves and that of phrenic and spinal accessary nerves
    Zhiqi Hou
    Department of Orthopaedic Surgery, First Hospital of Guangzhou City, Affiliated Guangzhou Medical College, Guangzhou 510180, China
    Chin J Traumatol 5:263-6. 2002
    ..To compare the effect of using partial median and ulnar nerves for treatment of C(5-6) or C(5-7) avulsion of the brachial plexus with that of using phrenic and spinal accessary nerves...
  21. ncbi Reverse end-to-side nerve transfer: from animal model to clinical use
    Santosh S Kale
    Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St Louis, MO, USA
    J Hand Surg Am 36:1631-1639.e2. 2011
    ..For nerve injuries in which incomplete regeneration is anticipated, a reverse end-to-side (RETS) nerve transfer might be useful to augment the regenerating nerve with additional axons and to more quickly reinnervate target ..
  22. ncbi Intercostal nerve transfer classification
    M Boulouednine
    Orthopaedic and Hand Surgery Department, Lapeyronie University Hospital, Montpellier, France
    Chir Main 20:136-7. 2001
    We report a new classification of intercostal nerve transfer. The specific application in brachial plexus reconstruction is described. This method was applied in intercostal nerve transfer to the musculocutaneous nerve in 15 patients...
  23. ncbi Nerve transfer to biceps muscle using a part of ulnar nerve for C5-C6 avulsion of the brachial plexus: anatomical study and report of four cases
    C Oberlin
    , , Paris, France
    J Hand Surg Am 19:232-7. 1994
    ..Ten percent of the bulk of the ulnar nerve was harvested for a suture directly to the motor nerve of the biceps with no significant impairment of hand function...
  24. ncbi Reconstruction of high ulnar nerve lesions by distal double median to ulnar nerve transfer
    B Battiston
    Department of Orthopaedics, CTO Hospital, Turin, Italy
    J Hand Surg Am 24:1185-91. 1999
    ..The length of the follow-up period ranged from 1 to 3.5 years. Results were graded by the Highet-Zachary scale. Good motor and sensory recovery was obtained in 6 cases; only return of protective sensation occurred in the remaining case...
  25. ncbi Nerve transfers: indications, techniques, and outcomes
    Thomas H Tung
    Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Hand Surg Am 35:332-41. 2010
    ....
  26. ncbi Anterior interosseous nerve transfer to the motor branch of the ulnar nerve for high ulnar nerve injuries
    Steven C Haase
    Department of Surgery, Section of Plastic Surgery, University of Michigan Medical Center, 1500 E Medical Center Drive, Ann Arbor, MI 48109, USA
    Ann Plast Surg 49:285-90. 2002
    ..For high ulnar nerve injuries, this type of nerve transfer is a much better approach than the traditional primary neurorrhaphy.
  27. ncbi Involuntary, electrically excitable nerve transfer for denervation: results from an animal model
    Daniel Master
    Department of Orthopaedic Surgery, University Hospitals Case Medical Center, Cleveland, OH 44106, USA
    J Hand Surg Am 34:479-487, 487.e1-3. 2009
    The purpose of this study was to evaluate the efficacy of "paralyzed" nerve transfer (ie, transfer of an involuntary, nondegenerated, electrically excitable nerve onto an involuntary, degenerated, non-electrically excitable nerve) and ..
  28. ncbi Specificity of muscle reinnervation following repair of the transected sciatic nerve. A comparative study of different repair techniques in the rat
    Q Zhao
    Department of Hand Surgery, General Hospital, , Sweden
    J Hand Surg Br 17:257-61. 1992
    ..There was no statistical significance between the other methods in respect of tetanic force. The specificity of muscle reinnervation was best after tubulization, repair with interfascicular grafts and perineurial suture...
  29. ncbi Optimizing skeletal muscle reinnervation with nerve transfer
    Samuel C Lien
    Department of Surgery, Section of Plastic and Reconstructive Surgery, University of Michigan, 2130 Taubman Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109 0340, USA
    Hand Clin 24:445-54, vii. 2008
    ..Only nerve transfer has been highly efficacious in changing the clinical outcomes of patients with skeletal muscle denervation, ..
  30. ncbi Median to radial nerve transfer to restore wrist and finger extension: technical nuances
    Justin M Brown
    Department of Neurological Surgery and Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, Washington University Medical Center, St Louis, Missouri 63110 1093, USA
    Neurosurgery 66:75-83; discussion 83. 2010
    ..We have described the utilization of distal nerve transfers for the restoration of radial nerve function in the forearm...
  31. ncbi Cortical plasticity following nerve transfer in the upper extremity
    Dimitri J Anastakis
    Division of Plastic Surgery, University of Toronto, 399 Bathurst Street, East Wing 2, Toronto, Ontario Canada M5G 2S8
    Hand Clin 24:425-44, vi-vii. 2008
    ..the important role that cortical plasticity and motor relearning play in functional recovery following a nerve transfer. Neurostimulation (transcranial magnetic stimulation), and neuroimaging (functional MRI, structural MRI, ..
  32. ncbi IGF-I and end-to-side nerve repair: a dose-response study
    D A Tiangco
    Eastern Virginia Medical School, Microsurgical Research Center, Norfolk 23501, USA
    J Reconstr Microsurg 17:247-56. 2001
    ..This study suggests that local infusion of IGF-I may expedite the functional recovery of a paralyzed muscle, by increasing the rate of axon regeneration through an end-to-side nerve graft...
  33. ncbi Nerve transfer with functioning free muscle transplantation
    David Chwei Chin Chuang
    Department of Plastic Surgery, Chang Gung Memorial Hospital, Chang Gung University, Taipei Linkou, 5, Fu Hsing Street, Kuei Shan, Taoyuan 33305, Taiwan
    Hand Clin 24:377-88, vi. 2008
    ..He outlines the eight major principles for nerve transfer with FFMT, basing his conclusions on the more than 333 patients who received FFMT between 1995 and 2005 in his ..
  34. ncbi Direct repair (nerve grafting), neurotization, and end-to-side neurorrhaphy in the treatment of brachial plexus injury
    Pavel Haninec
    Department of Neurosurgery, Third Faculty of Medicine, Charles University, Prague, Czech Republic
    J Neurosurg 106:391-9. 2007
    ....
  35. ncbi Intercostal nerve transfer of the musculocutaneous nerve in avulsed brachial plexus injuries: evaluation of 66 patients
    D C Chuang
    Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung Medical College, Taipei, Taiwan, Republic of China
    J Hand Surg Am 17:822-8. 1992
    Intercostal nerve transfer is a well-established and effective technique for irreparable avulsed brachial plexus injuries...
  36. ncbi Intercostal nerve transfer for brachial plexopathy
    J D Krakauer
    Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN 55905
    J Hand Surg Am 19:829-35. 1994
    Thirteen patients with traumatic brachial plexopathy underwent intercostal nerve transfer to the biceps motor branch (9 patients) or combined gracilis muscle and intercostal nerve transfer (4 patients; 3 for elbow flexion and 1 for elbow ..
  37. ncbi Restoration of elbow flexion in brachial plexus avulsion injury: comparing spinal accessory nerve transfer with intercostal nerve transfer
    S Waikakul
    Department of Orthopaedic Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Hand Surg Am 24:571-7. 1999
    ..performed to compare the clinical outcome of 2 types of commonly used nerve transfers, the spinal accessory nerve transfer and the intercostal nerve transfer...
  38. ncbi Preliminary results of double nerve transfer to restore elbow flexion in upper type brachial plexus palsies
    Phillipe A Liverneaux
    St Charles Hospital, Rochefort, France
    Plast Reconstr Surg 117:915-9. 2006
    ..The authors decided to investigate a double nerve transfer: one or more fascicles of the ulnar nerve to the nerve to the biceps and a fascicle of the median nerve to the ..
  39. ncbi Nerve transfers in facial palsy
    Julia K Terzis
    Microsurgical Research Center, Eastern Virginia Medical School, Norfolk, Virginia 23501, USA
    Facial Plast Surg 24:177-93. 2008
    ..The suitability of each nerve transfer is related to the type of facial palsy, time elapsed since injury, and the age and general health of the ..
  40. ncbi Restoration of shoulder function and elbow flexion by nerve transfer for poliomyelitis-like paralysis caused by enterovirus 71 infection
    S Funahashi
    Department of Orthopaedic Surgery, Hamamatsu University School of Medicine, 1 20 1 Handayama, Hamamatsu, Shizuoka 431 3192, Japan
    J Bone Joint Surg Br 89:246-8. 2007
    ..She recovered useful function after nerve transfers performed six months after the onset of paralysis. Early neurotisation can be used successfully in the treatment of poliomyelitis-like paralysis in children...
  41. ncbi Nerve transfer to serratus anterior muscle using the thoracodorsal nerve for winged scapula in C5 and C6 brachial plexus root avulsions
    Chairoj Uerpairojkit
    Upper Extremity and Reconstructive Microsurgery Unit, Institute of Orthopedics, Lerdsin General Hospital, Bangkok, Thailand
    J Hand Surg Am 34:74-8. 2009
    To report the results of nerve transfer to the serratus anterior muscle using the thoracodorsal nerve for winged scapula in C5 and C6 brachial plexus avulsion.
  42. ncbi Nerve transfers for severe nerve injury
    Bassam M J Addas
    Division of Neurosurgery, Department of Surgery, King Abdulaziz University Hospital, Jeddah, Kingdom of Saudi Arabia
    Neurosurg Clin N Am 20:27-38, vi. 2009
    ..This article provides the indications for nerve transfer, principles for their use, and a comprehensive survey on various intraplexal and extraplexal nerves that have ..
  43. ncbi Oberlin's ulnar nerve transfer to the biceps motor nerve in obstetric brachial plexus palsy: indications, and good and bad results
    Hassan Hamdy Noaman
    Reconstructive Surgery Unit, Franziskus Hospital, Aachen, Germany
    Microsurgery 24:182-7. 2004
    ..Oberlin's ulnar nerve transfer was done in 4 cases without brachial plexus exploration in those children with good shoulder function, and ..
  44. ncbi Brachial plexus injury: factors affecting functional outcome in spinal accessory nerve transfer for the restoration of elbow flexion
    Amir Samii
    Department of Neurosurgery, Nordstadt Medical Center, Klinikum Hannover, Germany
    J Neurosurg 98:307-12. 2003
    ....
  45. ncbi Patient outcome following a thoracodorsal to musculocutaneous nerve transfer for reconstruction of elbow flexion
    C B Novak
    Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Br J Plast Surg 55:416-9. 2002
    This study reports patient outcome following a thoracodorsal to musculocutaneous nerve transfer. We retrospectively reviewed the charts of six patients who had undergone transfer of the thoracodorsal nerve to the musculocutaneous nerve ..
  46. ncbi One-fascicle median nerve transfer to biceps muscle in C5 and C6 root avulsions of brachial plexus injury
    Adisak Sungpet
    Hand and Reconstructive Microsurgery Unit, Department of Orthopaedics, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand
    Microsurgery 23:10-3. 2003
    ..At the last follow-up examination, grip strength, pinch strength, moving two-point discrimination, and strength of wrist volar flexion on the affected side were not worse than before the operation in any patient...
  47. ncbi Long-range plasticity between intact hemispheres after contralateral cervical nerve transfer in humans
    Chuan tao Zuo
    Department of Hand Surgery, Huashan Hospital, Shanghai, People s Republic of China
    J Neurosurg 113:133-40. 2010
    ..plasticity was demonstrated in adults with brachial plexus avulsion injury (BPAI) who had received a contralateral cervical nerve transfer, and this plasticity reversed the BPAI-induced intrahemispheric cortical reorganization.
  48. ncbi Intratemporal facial nerve transfer with direct coaptation to the hypoglossal nerve
    Willem P Godefroy
    Department of Otorhinolaryngology, Leiden University Medical Centre, Leiden, The Netherlands
    Otol Neurotol 28:546-50. 2007
    To evaluate functional recovery after facial-hypoglossal nerve transfer with direct coaptation of the intratemporal part of the facial nerve.
  49. ncbi Sensory restoration in cortical level after a contralateral C7 nerve transfer to an injured arm in rats
    Meng Wang
    Department of Hand Surgery, Huashan Hospital, Shanghai Medical College of Fudan University, Shanghai, People s Republic of China
    Neurosurgery 67:136-43; discussion 143. 2010
    ..The restoration of sensory and motor function in brachial plexus root avulsion patients is a difficult challenge. The central nervous system plays an important role in sensory recovery after peripheral nerve injury and repair...
  50. ncbi Nerve transfers in adult brachial plexus injuries: my methods
    David Chwei Chin Chuang
    Department of Plastic Surgery, Chang Gung University Hospital, 199 Tun Hwa North Road, Taipei Linkou, Taipei 105, Taiwan
    Hand Clin 21:71-82. 2005
    ..The author's results show that nerve transfer can obtain an average of 60 degrees (range, 20 degrees - 180 degrees) of shoulder elevation without shoulder ..
  51. ncbi [Conservative treatment and rehabilitation in peripheral facial palsy]
    T Paternostro-Sluga
    Klinik für Physikalische Medizin und Rehabilitation, Medizinische Universität Wien, Allgemeines Krankenhaus Wien, Waehringer Guertel 18 20, Vienna, Austria
    Handchir Mikrochir Plast Chir 42:109-14. 2010
    ..Every patient with facial paralysis--regardless to the degree of lesion--should receive a brochure with mimic exercises and instructions to support facial symmetry as basic intervention...
  52. ncbi Outcomes of mini-hypoglossal nerve transfer and direct muscle neurotization for restoration of lower lip function in facial palsy
    Julia K Terzis
    Department of Surgery, Division of Plastic and Reconstructive Surgery, Microsurgical Research Center, Eastern Virginia Medical School, Norfolk, VA 23501, USA
    Plast Reconstr Surg 124:1891-904. 2009
    ..They report their experience with mini-hypoglossal nerve transfer for lower lip palsy.
  53. ncbi Nerve transfer to deltoid muscle using the intercostal nerves through the posterior approach: an anatomic study and two case reports
    Kanchai Malungpaishrope
    Upper Extremity and Reconstructive Microsurgery Unit, Institute of Orthopaedics, Lerdsin General Hospital, Bangkok, Thailand
    J Hand Surg Am 32:218-24. 2007
    ..The preliminary results of the clinical application of this procedure also are reported...
  54. ncbi Oberlin's ulnar nerve transfer to the biceps nerve in Erb's birth palsy
    M M Al-Qattan
    Plast Reconstr Surg 109:405-7. 2002
  55. ncbi Partial ulnar nerve transfer to the nerve to the biceps for the treatment of brachial plexopathy in metastatic breast carcinoma: case report
    Manzhi Wong
    Department of Hand and Reconstructive Microsurgery, National University Hospital, Singapore
    J Hand Surg Am 34:79-82. 2009
    ..We report a case of partial ulnar nerve transfer to the nerve to the biceps muscle to restore elbow flexion in a patient with combined radiation-induced and ..
  56. ncbi Distal anterior interosseous nerve transfer to the deep motor branch of the ulnar nerve for reconstruction of high ulnar nerve injuries
    Christine B Novak
    Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
    J Reconstr Microsurg 18:459-64. 2002
    ..This retrospective chart review evaluated patient outcome following a distal nerve transfer of the anterior interosseous nerve (AIN) to the deep motor branch of the ulnar nerve...
  57. ncbi Neurophysiologic and clinical outcome following medial pectoral to long thoracic nerve transfer for scapular winging: a case report
    Matthew M Tomaino
    Department of Orthopaedics, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Microsurgery 22:254-7. 2002
    ..Medial pectoral nerve transfer to the long thoracic nerve was performed via an 11-cm sural nerve graft to treat scapular winging 4 months ..
  58. ncbi Nerve transfer to deltoid muscle using the nerve to the long head of the triceps, part I: an anatomic feasibility study
    Kiat Witoonchart
    Upper Extremity and Reconstructive Microsurgery Unit, Institute of Orthopaedics, Lerdsin General Hospital, Bangkok, Thailand
    J Hand Surg Am 28:628-32. 2003
    ....
  59. ncbi Changing central nervous system control following intercostal nerve transfer
    M J Malessy
    Department of Neurosurgery, Leiden University Medical Center, The Netherlands
    J Neurosurg 89:568-74. 1998
    ..The goal of this study was to find which central nervous system (CNS) pathways are involved in volitional control over reinnervated biceps or pectoral muscles...
  60. ncbi Functional magnetic resonance imaging and control over the biceps muscle after intercostal-musculocutaneous nerve transfer
    Martijn J A Malessy
    Department of Neurosurgery, Leiden University Medical Center, Leiden, The Netherlands
    J Neurosurg 98:261-8. 2003
    ....
  61. ncbi Nerve transfer to biceps muscle using a part of the ulnar nerve in brachial plexus injury (upper arm type): a report of 32 cases
    S Leechavengvongs
    Institute of Orthopaedics, Lerdsin General Hospital Department of Medical Services, Bangkok, Thailand
    J Hand Surg Am 23:711-6. 1998
    Thirty-two patients with absent elbow flexion secondary to brachial plexus injury underwent nerve transfer using 1 or 2 fascicles of the ulnar nerve to the motor branch of the biceps muscle...
  62. ncbi Results of nerve transfer techniques for restoration of shoulder and elbow function in the context of a meta-analysis of the English literature
    G A Merrell
    Departments of Orthopaedic Surgery and Epidemiology and Public Health, Yale School of Medicine, New Haven, CT
    J Hand Surg Am 26:303-14. 2001
    We report the results of 15 patients who underwent nerve transfer for restoration of shoulder and elbow function at our institution for traumatic brachial plexus palsy...
  63. ncbi Long-term results of spinal accessory nerve transfer to the suprascapular nerve in upper-type paralysis of brachial plexus injury
    Kouichi Suzuki
    Department of Orthopedic Surgery, Ogori Daiichi General Hospital, Yoshiki gun, Yamaguchi 754 0002, Japan
    J Reconstr Microsurg 23:295-9. 2007
    ..We, therefore, conclude that repair of long thoracic nerve is mandatory for achieving optimum shoulder function...
  64. ncbi Technique of the double nerve transfer to recover elbow flexion in C5, C6, or C5 to C7 brachial plexus palsy
    Jean Noel Goubier
    International Center of Hand Surgery, Clinique du Parc Monceau, Paris, France
    Tech Hand Up Extrem Surg 11:15-7. 2007
    ..We describe the technique of this double transfer to restore elbow flexion. The results concerning 5 patients are presented...
  65. ncbi [Nerve and muscle transfer surgery to restore paralyzed elbow function]
    A Gohritz
    Klinik für Plastische, Hand und Wiederherstellungschirurgie, Zentrum für Schwerbrandverletzte, Medizinische Hochschule Hannover, Carl Neuberg Strasse 1, 30625 Hannover, Deutschland
    Unfallchirurg 111:85-101. 2008
    ..In tetraplegic patients, elbow extension is restored mainly by transfer of the posterior deltoid muscle extended with a tendon graft, or by means of a biceps-to-triceps transfer...
  66. ncbi Restoration of elbow function by intercostal nerve transfer for obstetrical paralysis with co-contraction of the biceps and the triceps
    K Kawano
    Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Tokyo, Japan
    J Hand Surg Eur Vol 32:421-6. 2007
    ..To overcome biceps/triceps co-contraction, we performed intercostal nerve transfer to the musculocutaneous nerve for three patients of age 11 months, 6 years and 9 years, respectively, and to ..
  67. ncbi Microsurgical reconstruction of obstetric brachial plexus palsy
    Liang Chen
    Hand Surgery Department, Hua Shan Hospital, Shanghai, China
    Microsurgery 28:108-12. 2008
    ..Most often, a conducting neuroma of the upper trunk is encountered, and it is believed that neuroma resection followed by microsurgical reconstruction of the brachial plexus gives the best results...
  68. ncbi Nerve transfers in children with traumatic partial brachial plexus injuries
    Jean Noel Goubier
    International Center of Hand Surgery, Clinique du Parc Monceau, 21 rue de Chazelles, 75017 Paris, France
    Microsurgery 28:117-20. 2008
    ..Nerve transfers have been performed. Shoulder abduction was restored by an accessory-to-suprascapular nerve transfer in one patient, while the triceps long head motor branch was transferred to the axillary nerve in both ..
  69. ncbi Restoration of shoulder function with nerve transfers in traumatic brachial plexus palsy patients
    Julia K Terzis
    Division of Plastic and Reconstructive Surgery, Eastern Virginia Medical School, Norfolk, VA 23510, USA
    Microsurgery 26:316-24. 2006
    ..Concomitant neurotization of the axillary nerve yields improved outcomes in shoulder abduction and external rotation function...
  70. ncbi Spinal accessory neurotization for restoration of elbow flexion in avulsion injuries of the brachial plexus
    P Songcharoen
    Department of Orthopaedic Surgery, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Hand Surg Am 21:387-90. 1996
    ..5% in patients who underwent operation later than 9 months after injury. This method of neurotization produces a result comparable with, if not better than, the results of other types of neurotization in restoration of elbow flexion...
  71. ncbi Combined nerve transfers for C5 and C6 brachial plexus avulsion injury
    Somsak Leechavengvongs
    Upper Extremity and Reconstructive Microsurgery Unit, Institute of Orthopaedics, Lerdsin General Hospital, Bangkok, Thailand
    J Hand Surg Am 31:183-9. 2006
    To report the results of combined nerve transfer in C5 and C6 brachial plexus avulsion injury.
  72. ncbi Cross-neurotization of the caudal brachial plexus with the contralateral C-8 ventral nerve branch in the cat. Potential surgical applications, effects of graft collection on the healthy donor limb and results
    C Carozzo
    Ecole Nationale Veterinaire de Lyon, Marcy l Etoile, France
    Neurochirurgie 51:89-105. 2005
    ..This can in turn enable the restoration of function, and could potentially lead to partial recovery after caudal brachial plexus avulsion in the cat...
  73. ncbi Shoulder function following partial spinal accessory nerve transfer for brachial plexus birth injury
    John A I Grossman
    Brachial Plexus Program, Miami Children s Hospital, Miami, FL 33176, USA
    J Plast Reconstr Aesthet Surg 59:373-5. 2006
    ..At a minimum follow-up of 2.5 years, all children had shoulder function of Grade 4 or better using a modified Gilbert Scale. Average lateral rotation was measured at 53 degrees...
  74. ncbi Neuronal survival, regeneration and musclemorphology after posterior C7 nerve transfer: an experimental study
    C G Zhang
    Section for Hand and Plastic Surgery, Department of Surgical and Perioperative Science, University Hospital, Umea, Sweden
    J Plast Reconstr Aesthet Surg 59:717-25. 2006
    C7 nerve transfer has been widely used in treating brachial plexus avulsion injuries...
  75. ncbi Did the partial contralateral C7-transfer fulfil our expectations? Results after 5 year experience
    R Hierner
    Plastic, Reconstructive and Aesthetic Surgery, Center for Interdisciplinary Reconstructive Surgery, Microsurgery, Hand Surgery, Burns, University Hospital Gasthuisberg, Catholic University Leuven, Leuven, Belgium
    Acta Neurochir Suppl 100:33-5. 2007
    ..Within the last decade contralateral C7-transfer has become a new source of axon donor in complete brachial plexus lesions...
  76. ncbi The surgical treatment of brachial plexus injuries in adults
    Julia K Terzis
    Department of Surgery, Division of Plastic Surgery, Eastern Virginia Medical School, Norfolk, VA 23501, USA
    Plast Reconstr Surg 119:73e-92e. 2007
    ..3. Describe various nerve reconstructive strategies and make appropriate selection of secondary procedures for shoulder stability, elbow flexion, and hand reanimation. 4. Anticipate the possible functional outcome...
  77. ncbi Quantitation of the lower subscapular nerve for potential use in neurotization procedures
    R Shane Tubbs
    Department of Cell Biology and School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama 35233, USA
    J Neurosurg 105:881-3. 2006
    ..Nerves in the vicinity of the axillae have been commonly used for neural grafting procedures, with the exception of the lower subscapular nerve (LSN)...
  78. ncbi Experimental neurotisation of the brachial plexus by means of nerve grafting from the corticospinal tract of the proximal spinal cord at the T3-T4 level
    G A Brunelli
    Fondazione Midollo Spinale, Brescia, Italy
    J Hand Surg Eur Vol 32:620-5. 2007
    ....
  79. ncbi Physiological and clinical advantages of median nerve fascicle transfer to the musculocutaneous nerve following brachial plexus root avulsion injury
    Rahul K Nath
    Texas Nerve and Paralysis Institute, Houston, Texas 77030, USA
    J Neurosurg 105:830-4. 2006
    ..In the current study the authors examine the efficacy of an alternative technique using median nerve fascicles transferred to the musculocutaneous nerve to reinnervate the biceps muscle...
  80. ncbi Restoration of sensibility in the hand after complete brachial plexus injury
    K Ihara
    Department of Orthopaedic Surgery, Yamaguchi University School of Medicine, Japan
    J Hand Surg Am 21:381-6. 1996
    ..No moving two-point discrimination was restored in any case. While the best recovery obtained was only at the S2+ level, even this limited sensibility was useful for otherwise completely anesthetic patients...
  81. ncbi Posterior approach technique for accessory-suprascapular nerve transfer: a cadaveric study of the anatomical landmarks and number of myelinated axons
    D Pruksakorn
    Department of Orthopaedics, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand
    Clin Anat 20:140-3. 2007
    Accessory-suprascapular nerve transfer by the anterior supraclavicular approach technique was suggested to ensure transferrance of the spinal accessory nerve to healthy recipients...
  82. ncbi Anatomical and functional connectivity of the transected ulnar nerve after accessory nerve neurotization in the cat
    A Isla
    Department of Neurosurgery, La Paz University Hospital, Autonoma University, Madrid, Spain
    J Neurosurg Sci 50:33-40. 2006
    ..The objective of this experimental study was to test the capacity of accessory nerve motoneurons to innervate muscles of the ulnar nerve territory after direct anastomosis...
  83. ncbi Pain phenomena and sensory recovery following brachial plexus avulsion injury and surgical repairs
    M Htut
    The Royal National Orthopaedic Hospital, Stanmore, Hammersmith Hospital, London, and St Mary s Hospital, London, UK
    J Hand Surg Br 31:596-605. 2006
    ..Understanding sensory mechanisms will help develop new treatments for severe brachial plexus injuries...
  84. ncbi Living-donor nerve transplantation for global obstetric brachial plexus palsy
    Scott A Gruber
    Division of Immunology and Organ Transplantation, Department of Surgery, Houston, TX, USA
    J Reconstr Microsurg 22:245-54. 2006
    ..Cross-chest C7 nerve transfer and temporary tacrolimus/prednisone immunosuppression were utilized...
  85. ncbi Restoration of prehension using double free muscle technique after complete avulsion of brachial plexus in children: a report of three cases
    Yasunori Hattori
    Department of Orthopedic Surgery, Ogori Daiichi General Hospital and Yamaguchi University School of Medicine, Ogori, Yamaguchi, Japan
    J Hand Surg Am 30:812-9. 2005
    ..Brachial plexus injury in children, excluding birth palsy, is relatively rare and seldom reported. We report our technique, the results of this procedure, and problems we encountered in treating children with brachial plexus injury...
  86. ncbi Update on management of pediatric brachial plexus palsy
    Peter M Waters
    Department of Orthopedic Surgery, Harvard Medical School, Children s Hospital Boston, Boston, Massachusetts, USA
    J Pediatr Orthop B 14:233-44. 2005
    ..Recommendations for microsurgery and shoulder reconstruction will be based on the present evidence from the literature...
  87. ncbi Nerve transfers for severe brachial plexus injuries: a review
    Rajiv Midha
    Division of Neurosurgery, Department of Surgery, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Ontario, Canada
    Neurosurg Focus 16:E5. 2004
    b>Nerve transfer procedures are increasingly performed for repair of severe brachial plexus injury (BPI), in which the proximal spinal nerve roots have been avulsed from the spinal cord...
  88. ncbi Suprascapular nerve reconstruction in 118 cases of adult posttraumatic brachial plexus
    Julia K Terzis
    Division of Plastic and Reconstructive Surgery, Department of Surgery, Eastern Virginia Medical School, International Institute of Reconstructive Microsurgery, Norfolk, VA, USA
    Plast Reconstr Surg 117:613-29. 2006
    ..Outcomes were analyzed in relation to various factors, including patient age, denervation time, donor nerve used, and functional restoration achieved in the supraspinatus versus the infraspinatus muscles...
  89. ncbi Phrenic nerve transfer in the treatment of brachial plexus avulsion: an experimental study of nerve regeneration and muscle morphology in rats
    Cheng Gang Zhang
    Department of Hand and Plastic Surgery, University Hospital, Umea, Sweden
    Microsurgery 24:232-40. 2004
    The regeneration of motor and sensory neurons and the morphological changes of the target muscle after phrenic nerve transfer were investigated in adult rats. Six months following nerve transfer, 326.0 +/- 16...
  90. ncbi [Surgery of post-traumatic brachial plexus lesions (personal approach in 2003)]
    H Millesi
    Wiener Privatklinik, Vienna, Austria
    Handchir Mikrochir Plast Chir 36:29-36. 2004
    ..At present (in the year 2003), five different approaches are utilised: A simple nerve transfer to restore elbow flexion without exploration of the brachial plexus is still recommended...
  91. ncbi Nerve transfers to the biceps and brachialis branches to improve elbow flexion strength after brachial plexus injuries
    Thomas H Tung
    Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, St Louis, Missouri, USA
    J Neurosurg 98:313-8. 2003
    ..In this study the authors evaluated the outcome in patients with brachial plexus injuries who underwent nerve transfers to the biceps and the brachialis branches of the musculocutaneous nerve...
  92. ncbi Surgical treatment of brachial plexus traction injuries in children, excluding obstetric palsy
    Tarek Abdalla El-Gammal
    Reconstructive Microsurgery Unit, Department of Orthopedics and Traumatology, Assiut University School of Medicine, Assiut, Egypt
    Microsurgery 23:14-7. 2003
    ..Given the frequency of root avulsions, neurotization is often required...
  93. ncbi Reconstruction of C5 and C6 brachial plexus avulsion injury by multiple nerve transfers: spinal accessory to suprascapular, ulnar fascicles to biceps branch, and triceps long or lateral head branch to axillary nerve
    Jayme Augusto Bertelli
    Department of Orthopedic Surgery, Governador Celso Ramos Hospital, Praça Getulio Vargas 322, Florianopolis, Santa Catarina 88020030, Brazil
    J Hand Surg Am 29:131-9. 2004
    ..The purpose of this study was to describe and report the results of the use of multiple nerve transfers in the reconstruction of these avulsion injuries...
  94. ncbi Transfer of pectoral nerves to the musculocutaneous nerve in obstetric upper brachial plexus palsy
    Gerhard Blaauw
    Department of Neurosurgery, University Hospital Maastricht, Maastricht, The Netherlands
    Neurosurgery 53:338-41; discussion 341-2. 2003
    ..To investigate the results of transfer of pectoral nerves to the musculocutaneous nerve for treatment of obstetric brachial palsy...
  95. ncbi End-to-side nerve suture in clinical practice
    Ulrich Mennen
    Department of Hand and Microsurgery, Medical University of Southern Africa, Pretoria, South Africa
    Hand Surg 8:33-42. 2003
    ..ETSNS restores function in conditions previously difficult to operate, and may replace nerve grafting in many instances. It provides an additional method in our armamentarium in peripheral nerve surgery...
  96. ncbi Brachial plexus avulsion injury repairs with nerve transfers and nerve grafts directly implanted into the spinal cord yield partial recovery of shoulder and elbow movements
    Jayme Augusto Bertelli
    Hospital Governador Celso Ramos, Praça Getulio Vargas 322, Florianopolis, Santa Catarina 88020030, Brazil
    Neurosurgery 52:1385-9; discussion 1389-90. 2003
    ..The current treatment is based on nerve transfers, which yield very limited recovery. In this study, brachial plexus injuries were repaired with nerve transfers and nerve grafts directly implanted into the spinal cord...
  97. ncbi Morphologic and functional study of rat median nerve repair by terminolateral neurorrhaphy of the ulnar nerve
    Igor Papalia
    Dipartimento di Discipline Chirurgiche Generali e Speciali, Universita di Messina, Italy
    J Reconstr Microsurg 19:257-64. 2003
    ....
  98. ncbi Restoration of hand function and so called "breathing arm" after intraspinal repair of C5-T1 brachial plexus avulsion injury. Case report
    Thomas Carlstedt
    The Periphery Nerve Injury Unit, The Royal National Orthopaedic Hospital, Stanmore, United Kingdom
    Neurosurg Focus 16:E7. 2004
    ..To the best of the authors' knowledge, the present case demonstrates, for the first time, that spinal cord surgery can restore hand function after a complete brachial plexus avulsion injury...
  99. ncbi Full-length phrenic nerve transfer by means of video-assisted thoracic surgery in treating brachial plexus avulsion injury
    Wen Dong Xu
    Institute of Hand Surgery, Hua Shan Hospital, Shanghai 200040, PR China
    Plast Reconstr Surg 110:104-9; discussion 110-1. 2002
    Phrenic nerve transfer has been widely used in treating brachial plexus avulsion injury...
  100. ncbi The use of thoracodorsal nerve transfer in restoration of irreparable C5 and C6 spinal nerve lesions
    M M Samardzic
    Institute of Neurosurgery, Clinical Center of Serbia, Visegradska 26, 11000 Belgrade, Serbia and Montenegro
    Br J Plast Surg 58:541-6. 2005
    ..this study, we analysed outcome and time-course of recovery in correlation with recipient nerves and type of nerve transfer (isolated or in combination with other collateral branches) for 27 patients with transfer to the ..
  101. ncbi Contribution of the distal nerve sheath to nerve and muscle preservation following denervation and sensory protection
    Karen Veltri
    Department of Medical Sciences, Division of Behavioral Neurosciences, McMaster University, Hamilton, Ontario, Canada
    J Reconstr Microsurg 21:57-70; discussion 71-4. 2005
    ..The authors conclude that sensory protection of muscle does not require the distal nerve sheath, but that preservation of the distal sheath may contribute to enhanced nerve regeneration...

Research Grants7

  1. URINARY BLADDER MUSCARINIC RECEPTOR SUBTYPES
    MICHAEL RUGGIERI; Fiscal Year: 2003
    ..3. To characterize the changes in M2 M3 receptor phosphorylation that may accompany receptor desensitization and receptor up and down regulation. ..
  2. Role of Endogenous Opioid System in the Placebo Effect
    James Campbell; Fiscal Year: 2006
    ..3) Identify relationships between the magnitude of the placebo response and regional mu opioid receptor availability in a non-painful condition. ..
  3. A role for dopamine in brain development
    Pradeep Bhide; Fiscal Year: 2007
    ..It is also an excellent model to mimic dopamine imbalance in the CNS that can be produced by therapeutic drugs that intentionally or unintentionally target the dopaminergic system of the developing brain. ..
  4. MECHANISMS OF NEUROPATHIC PAIN
    James Campbell; Fiscal Year: 2008
    ..These studies will provide a biological rationale for the development of peripheral treatments for neuropathic pain. [unreadable] [unreadable] [unreadable]..
  5. HYPOTHERMIA FOR SEVERE TBI IN CHILDREN
    P David Adelson; Fiscal Year: 2004
    ....
  6. COCAINE AND BRAIN DEVELOPMENT
    Pradeep G Bhide; Fiscal Year: 2010
    ..The proposed studies promise novel insights into the mechanism of cocaine's action on fetal brain development by examining the link between cocaine, dopamine and development of GABA circuits. ..
  7. Surgical Management of Facial Nerve Injury
    Theresa Hadlock; Fiscal Year: 2007
    ..The academic environment is one of complete dedication to advancing both biomedical science and patient care through careful study and diligent investigation, and of support for the mentored investigator. [unreadable] [unreadable]..