laminectomy

Summary

Summary: Excision of the posterior arch of a vertebra. (Dorland, 28th ed)

Top Publications

  1. ncbi 1997 Volvo Award winner in clinical studies. Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective, randomized study comparing decompressive laminectomy and arthrodesis with and without spinal instrumentation
    J S Fischgrund
    William Beaumont Hospital, Department of Orthopaedic Surgery, Royal Oak, Michigan, USA
    Spine (Phila Pa 1976) 22:2807-12. 1997
  2. ncbi Visceral and vascular complications resulting from anterior lumbar interbody fusion
    V Rajaraman
    Division of Neurosurgery, New Jersey Medical School, Newark 07013, USA
    J Neurosurg 91:60-4. 1999
  3. ncbi Modified plate-only open-door laminoplasty versus laminectomy and fusion for the treatment of cervical stenotic myelopathy
    Lili Yang
    Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, China
    Orthopedics 36:e79-87. 2013
  4. ncbi Dynamic stabilization for degenerative lumbar scoliosis in elderly patients
    Mario Di Silvestre
    Spine Surgery Department, Istituti Ortopedici Rizzoli, Bologna, Italy
    Spine (Phila Pa 1976) 35:227-34. 2010
  5. ncbi Spinal cord stimulation electrode design: a prospective, randomized, controlled trial comparing percutaneous with laminectomy electrodes: part II-clinical outcomes
    Richard B North
    Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287 7881, USA
    Neurosurgery 57:990-6; discussion 990-6. 2005
  6. ncbi Spinal cord stimulation electrode design: prospective, randomized, controlled trial comparing percutaneous and laminectomy electrodes-part I: technical outcomes
    Richard B North
    Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287 7713, USA
    Neurosurgery 51:381-9; discussion 389-90. 2002
  7. ncbi Spinal cord infarction after decompressive laminectomy for spontaneous spinal epidural hematoma--case report
    Juno Park
    Department of Neurosurgery, Korea University Ansan Hospital, Korea University School of Medicine, Seoul, R O K
    Neurol Med Chir (Tokyo) 47:325-7. 2007
  8. ncbi Spinal deformity and instability after multilevel cervical laminectomy for spondylotic myelopathy
    P Guigui
    Orthopaedic Department, , Clichy, France
    Spine (Phila Pa 1976) 23:440-7. 1998
  9. ncbi Laminoplasty versus laminectomy and fusion for multilevel cervical myelopathy: an independent matched cohort analysis
    J G Heller
    Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia, USA
    Spine (Phila Pa 1976) 26:1330-6. 2001
  10. ncbi Spinal neurinomas: retrospective analysis and long-term outcome of 179 consecutively operated cases and review of the literature
    Piero Conti
    Department of Neurosurgery, University of Florence, Florence, Italy
    Surg Neurol 61:34-43; discussion 44. 2004

Research Grants

  1. Neural Prosthetic Control of Continence and Micturition
    Warren M Grill; Fiscal Year: 2013
  2. Device for Surgical Adhesion Prevention
    REKHA BANSAL; Fiscal Year: 2010
  3. Air Barrier System to reduce contamination of wounds during surgery
    SEAN SELF; Fiscal Year: 2013
  4. An injectable biocompatible hydrogel nucleus pulposus replacement
    Gavin Braithwaite; Fiscal Year: 2009
  5. BACK PAIN OUTCOME ASSESSMENT TEAM
    Richard Deyo; Fiscal Year: 1991
  6. FORE-SCI TRAINING PROGRAM (RFP 08-01)
    DANA MCTIGUE; Fiscal Year: 2011
  7. FORE-SCI TRAINING PROGRAM (RFP 08-01)
    Dana M McTigue; Fiscal Year: 2009
  8. FORE-SCI TRAINING PROGRAM (RFP 08-01)
    DANA MCTIGUE; Fiscal Year: 2012
  9. Voltage gated sodium channels in acute post laminectomy pain
    CHRISTINA MARIE SPOFFORD; Fiscal Year: 2013
  10. A Novel Approach to Prevent Periduaral Fibrosis
    James Pachence; Fiscal Year: 2001

Detail Information

Publications316 found, 100 shown here

  1. ncbi 1997 Volvo Award winner in clinical studies. Degenerative lumbar spondylolisthesis with spinal stenosis: a prospective, randomized study comparing decompressive laminectomy and arthrodesis with and without spinal instrumentation
    J S Fischgrund
    William Beaumont Hospital, Department of Orthopaedic Surgery, Royal Oak, Michigan, USA
    Spine (Phila Pa 1976) 22:2807-12. 1997
    ....
  2. ncbi Visceral and vascular complications resulting from anterior lumbar interbody fusion
    V Rajaraman
    Division of Neurosurgery, New Jersey Medical School, Newark 07013, USA
    J Neurosurg 91:60-4. 1999
    ..The causes, strategies for their avoidance, and the clinical course of these complications are also discussed...
  3. ncbi Modified plate-only open-door laminoplasty versus laminectomy and fusion for the treatment of cervical stenotic myelopathy
    Lili Yang
    Department of Orthopedics, Changzheng Hospital, Second Military Medical University, Shanghai, China
    Orthopedics 36:e79-87. 2013
    The purpose of this study was to compare modified plate-only laminoplasty and laminectomy and fusion to confirm which of the 2 surgical modalities could achieve a better decompression outcome and whether a significant difference was ..
  4. ncbi Dynamic stabilization for degenerative lumbar scoliosis in elderly patients
    Mario Di Silvestre
    Spine Surgery Department, Istituti Ortopedici Rizzoli, Bologna, Italy
    Spine (Phila Pa 1976) 35:227-34. 2010
    ..A retrospective study...
  5. ncbi Spinal cord stimulation electrode design: a prospective, randomized, controlled trial comparing percutaneous with laminectomy electrodes: part II-clinical outcomes
    Richard B North
    Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287 7881, USA
    Neurosurgery 57:990-6; discussion 990-6. 2005
    ..in use for more than 30 years, has evolved into an easily implemented technique involving percutaneous or laminectomy electrode placement...
  6. ncbi Spinal cord stimulation electrode design: prospective, randomized, controlled trial comparing percutaneous and laminectomy electrodes-part I: technical outcomes
    Richard B North
    Department of Neurosurgery, School of Medicine, Johns Hopkins University, Baltimore, Maryland 21287 7713, USA
    Neurosurgery 51:381-9; discussion 389-90. 2002
    ..Contemporary electrodes can be placed percutaneously in some cases and require a limited laminectomy in other cases.
  7. ncbi Spinal cord infarction after decompressive laminectomy for spontaneous spinal epidural hematoma--case report
    Juno Park
    Department of Neurosurgery, Korea University Ansan Hospital, Korea University School of Medicine, Seoul, R O K
    Neurol Med Chir (Tokyo) 47:325-7. 2007
    ..Surgeons should consider the possibility of this devastating complication before aggressive and early surgical intervention in a patient with SSEH causing cord compression and neurological deficit...
  8. ncbi Spinal deformity and instability after multilevel cervical laminectomy for spondylotic myelopathy
    P Guigui
    Orthopaedic Department, , Clichy, France
    Spine (Phila Pa 1976) 23:440-7. 1998
    ..To describe the incidence and consequences of cervical spinal deformity and instability after multilevel laminectomy in adult patients with myelopathy caused by cervical spondylosis and to determine the usefulness of ..
  9. ncbi Laminoplasty versus laminectomy and fusion for multilevel cervical myelopathy: an independent matched cohort analysis
    J G Heller
    Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia, USA
    Spine (Phila Pa 1976) 26:1330-6. 2001
    A matched cohort clinical and radiographic retrospective analysis of laminoplasty and laminectomy with fusion for the treatment of multilevel cervical myelopathy.
  10. ncbi Spinal neurinomas: retrospective analysis and long-term outcome of 179 consecutively operated cases and review of the literature
    Piero Conti
    Department of Neurosurgery, University of Florence, Florence, Italy
    Surg Neurol 61:34-43; discussion 44. 2004
    ..We decided to limit the retrospective study to obtain at least 5 years of follow-up. Therefore, 20 additional neurinomas treated between 1997 and 2002 were excluded...
  11. ncbi Surgery for lumbar spinal stenosis. Attempted meta-analysis of the literature
    J A Turner
    Department of Psychiatry and Behavioral Sciences, University of Washington, Seattle
    Spine (Phila Pa 1976) 17:1-8. 1992
    ..Few patient characteristics were found to predict outcome. Major deficits in study design, analysis, and reporting were common, and these precluded firm conclusions...
  12. ncbi Cervical laminectomy vs laminoplasty: is there a difference in outcome and postoperative pain?
    Besnik Nurboja
    Department of Neurosurgery, Kings College Hospital, London, United Kingdom
    Neurosurgery 70:965-70; discussion 970. 2012
    ..Cervical laminoplasty is often used for the decompression of multilevel cervical spondylotic myelopathy without creating spinal instability and kyphosis...
  13. pmc The effectiveness of poloxamer 407-based new anti-adhesive material in a laminectomy model in rats
    Chang Hun Yu
    Department of Orthopedic Surgery, Seoul National University, College of Medicine, Seoul 156 707, Korea
    Eur Spine J 21:971-9. 2012
    In the laminectomy model in rats, to verify anti-adhesive effectiveness of the new material, a mixture composed of poloxamer 407, calcium chloride, and xanthorrhizol, we compared it with that of commercially used solution form anti-..
  14. ncbi The effect of 10-hydroxycamptothecine in preventing fibroblast proliferation and epidural scar adhesion after laminectomy in rats
    Yu Sun
    Department of Orthopedics, The First Affiliated Hospital of Nanjing Medical University, Guangzhou Road 300, Nanjing, Jiangsu Province, China
    Eur J Pharmacol 593:44-8. 2008
    ..HCPT) on fibroblast proliferation and pathological changes in epidural scar tissue after laminectomy. Here we illustrated the effect of HCPT on fibroblast proliferation and epidural scar adhesion after ..
  15. ncbi Intradiscal pressure and kinematic behavior of lumbar spine after bilateral laminotomy and laminectomy
    Raj D Rao
    Department of Orthopaedic Surgery, Medical College of Wisconsin, 9200 West Wisconsin Avenue, Milwaukee, WI 53226, USA
    Spine J 2:320-6. 2002
    Bilateral laminotomy has been proposed as an alternative to laminectomy for decompression of lumbar spinal stenosis. Preservation of the posterior midline ligaments with laminotomy is presumed to maintain spinal segment stability...
  16. pmc Cervical spine surgery: an historical perspective
    Vincenzo Denaro
    Department of Orthopaedics and Trauma Surgery, University Campus Bio Medico of Rome, Via Alvaro del Portillo, 200, 00128, Rome, Italy
    Clin Orthop Relat Res 469:639-48. 2011
    ..Continued innovation in surgery requires a knowledge and understanding of historical advances with a recognition of successes and failures...
  17. ncbi Cervical laminectomy for the treatment of cervical degenerative myelopathy
    Timothy C Ryken
    Department of Neurosurgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA
    J Neurosurg Spine 11:142-9. 2009
    The objective of this systematic review was to use evidence-based medicine to examine the efficacy of cervical laminectomy for the treatment of cervical spondylotic myelopathy (CSM).
  18. ncbi Biomechanical effects of laminoplasty versus laminectomy: stenosis and stability
    Venkat Subramaniam
    Department of Neurosurgery Research, Spinal Biomechanics Laboratory, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, AZ 85013, USA
    Spine (Phila Pa 1976) 34:E573-8. 2009
    ..In vitro human cadaveric study simultaneously quantifying sagittal plane flexibility and spinal canal stenosis...
  19. ncbi The effect of bilateral laminotomy versus laminectomy on the motion and stiffness of the human lumbar spine: a biomechanical comparison
    Michael J Lee
    University of Washington Medical Center, Department of Sports Medicine and Orthopaedic Surgery, Seattle, WA 98195, USA
    Spine (Phila Pa 1976) 35:1789-93. 2010
    A cadaveric simulation model of the lumbar spine was used to study the intervertebral motion characteristics of the lumbar spine after bilateral laminotomy and facet-sparing laminectomy.
  20. ncbi A comparison of the effectiveness of mitomycin C and 5-fluorouracil in the prevention of peridural adhesion after laminectomy
    Yu Sun
    Department of Orthopedics, First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu Province, People s Republic of China
    J Neurosurg Spine 7:423-8. 2007
    The effectiveness of the topical application of mitomycin C (MMC) or 5-fluorouracil (5FU) in preventing peridural adhesion after laminectomy was compared in this study.
  21. ncbi A prospective, randomized trial comparing expansile cervical laminoplasty and cervical laminectomy and fusion for multilevel cervical myelopathy
    Glen R Manzano
    Department of Neurological Surgery and the Miami Project to Cure Paralysis, University of Miami Miller School of Medicine, Miami, Florida 33136, USA
    Neurosurgery 70:264-77. 2012
    ..Controversy exists as to the best posterior operative procedure to treat multilevel compressive cervical spondylotic myelopathy...
  22. ncbi A comparison of anterior cervical fusion, cervical laminectomy, and cervical laminoplasty for the surgical management of multiple level spondylotic radiculopathy
    H N Herkowitz
    Department of Orthopaedic Surgery, William Beaumont Hospital, Royal Oak, Michigan
    Spine (Phila Pa 1976) 13:774-80. 1988
    ..Bilateral and multiple level laminectomy carries the risk of potential instability...
  23. ncbi Alpha-lipoic acid reduces peridural fibrosis after laminectomy of lumbar vertebrae in rabbits
    Miktat Kaya
    Department of Neurosurgery, Faculty of Medicine, Kafkas University, Kars, Turkey, 36100
    Acta Neurochir (Wien) 154:1241-5. 2012
    ..In this study, alpha-lipoic acid (ALA), reported to reduce fibrosis in liver, oral mucosa, and peritoneum, investigated as a potential candidate for prevention of peridural fibrosis...
  24. ncbi Combined laminectomy and thoracoscopic resection of dumbbell-type thoracic cord tumor
    S Konno
    Department of Orthopaedic Surgery, Fukushima Medical University, Fukushima City, Japan
    Spine (Phila Pa 1976) 26:E130-4. 2001
    ..A study of five patients whose dumbbell or paraspinal tumors of the thoracic spine were managed by using thoracoscopic surgery is reported...
  25. pmc A prospective randomised study on the long-term effect of lumbar fusion on adjacent disc degeneration
    Per Ekman
    Division of Orthopedics, Department of Clinical Science, Intervention and Technology CLINTEC, Karolinska University Hospital Huddinge, Karolinska Institutet, 141 86, Stockholm, Sweden
    Eur Spine J 18:1175-86. 2009
    ..There were no significant differences between instrumented and non-instrumented patients. In patients with laminectomy we found a significantly higher incidence of ASD compared to non laminectomised patients (22/47 vs...
  26. ncbi Axial symptoms after cervical laminoplasty with C3 laminectomy compared with conventional C3-C7 laminoplasty: a modified laminoplasty preserving the semispinalis cervicis inserted into axis
    Kazunari Takeuchi
    Department of Orthopaedic Surgery, Hirosaki University School of Medicine, Hirosaki, Japan
    Spine (Phila Pa 1976) 30:2544-9. 2005
    Results of C4-C7 laminoplasty with C3 laminectomy and C3-C7 laminoplasty were compared.
  27. pmc Anterior shear strength of the porcine lumbar spine after laminectomy and partial facetectomy
    Guido B van Solinge
    Department of Orthopedic Surgery, VU University Medical Center, Amsterdam, The Netherlands
    Eur Spine J 19:2130-6. 2010
    ..The standard surgical management is decompression of the spinal canal by laminectomy and partial facetectomy...
  28. ncbi Analysis and prevention of spinal column deformity following cervical laminectomy. I. Pathogenetic analysis of postlaminectomy deformities
    T Saito
    Department of Orthopaedic Surgery, Faculty of Medicine, Kyoto University
    Spine (Phila Pa 1976) 16:494-502. 1991
    ..Progressive kyphotic deformity is found only in children...
  29. pmc The surgical treatment for spinal intradural extramedullary tumors
    Dong Ki Ahn
    Department of Orthopedic Surgery, Seoul Sacred Heart General Hospital, Seoul, Korea
    Clin Orthop Surg 1:165-72. 2009
    ..We wanted to investigate the results of surgical treatment and analyze the factors that have an influence on the neurologic symptoms and prognosis of spinal intradural extramedullary (IDEM) tumors...
  30. ncbi Osteochondroma of the spine: an enigmatic tumor of the spinal cord. A series of 10 cases
    M C Sharma
    Department of Pathology, All India Institute of Medical Sciences, New Delhi, India
    J Neurosurg Sci 46:66-70; discussion 70. 2002
    ..Osteochondro-mas are common benign bony lesions of long bones but involvement of spine by solitary osteochondroma and its presentation as compressive myelopathy is rare. Most of the literature is in the form of case reports...
  31. pmc C3-6 laminoplasty takes over C3-7 laminoplasty with significantly lower incidence of axial neck pain
    N Hosono
    Department of Spine Surgery, Osaka Kosei Nenkin Hospital, Osaka, Japan
    Eur Spine J 15:1375-9. 2006
    ..4% vs. 29%, P=0.015). Due to its simplicity and various benefits, C3-6 laminoplasty is a promising alternative to conventional C3-7 laminoplasty for treatment of multisegmental compression myelopathy...
  32. ncbi C5 palsy after laminectomy and posterior cervical fixation for ossification of posterior longitudinal ligament
    Yu Chen
    Department of Orthopedic Surgery, Changzheng Hospital, Shanghai, China
    J Spinal Disord Tech 20:533-5. 2007
    To investigate the imaging findings correlated with C5 root palsies in the patients undergoing laminectomy and lateral mass screw fixation for ossification of posterior longitudinal ligament (OPLL), and clarify its pathogenic mechanism.
  33. ncbi A prospective randomized study of clinical outcomes in patients with cervical compressive myelopathy treated with open-door or French-door laminoplasty
    Motohiro Okada
    Department of Orthopaedic Surgery, Wakayama Medical University, Wakayama, Japan
    Spine (Phila Pa 1976) 34:1119-26. 2009
    ..A prospective randomized clinical study...
  34. ncbi Intradural lumbar disc herniations: the role of MRI in preoperative diagnosis and review of the literature
    Giancarlo D'Andrea
    Department of Neurological Sciences, La Sapienza University, Rome, Italy
    Neurosurg Rev 27:75-80; discussion 81-2. 2004
    ..The three patients previously operated (1, 2, 7) showed good outcome. Presently, we believe that radiologic diagnosis of intradural herniation is possible in carefully selected patients, thanks to MRI with gadolinium...
  35. ncbi Comparison of the results of laminectomy and open-door laminoplasty for cervical spondylotic myeloradiculopathy and ossification of the posterior longitudinal ligament
    N Nakano
    Nakano Orthopaedic Hospital, Sapporo, Japan
    Spine (Phila Pa 1976) 13:792-4. 1988
    b>Laminectomy was performed on 14 patients with cervical radiculomyelopathy and ossification of the posterior longitudinal ligament (OPLL). Since 1978, simple open-door laminoplasties have been performed on 75 patients...
  36. ncbi Laminectomy and fusion for the treatment of cervical degenerative myelopathy
    Paul A Anderson
    Department of Orthopaedic Surgery, University of Wisconsin, Madison, Wisconsin, USA
    J Neurosurg Spine 11:150-6. 2009
    The objective of this systematic review was to use evidence-based medicine to examine the efficacy of cervical laminectomy and fusion for the treatment of cervical spondylotic myelopathy (CSM).
  37. ncbi Lumbar facet fracture as a possible source of pain after lumbar laminectomy
    C Rosen
    Rancho Los Amigos Medical Center, Downey, California
    Spine (Phila Pa 1976) 16:S234-8. 1991
    This study compared 50 patients with lumbar facet fractures and continued pain after lumbar laminectomy with a postlaminectomy control group without facet fractures...
  38. ncbi The surgical approach to "dumbbell tumors" of the mediastinum
    M Behgam Shadmehr
    Division of General Thoracic Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA
    Ann Thorac Surg 76:1650-4. 2003
    ..Correct preoperative assessment of neuroforaminal extension is important to avoid spinal cord injury. The surgical approach remains controversial...
  39. ncbi Spinal dumbbell tumors: an analysis of a series of 118 cases
    Hiroshi Ozawa
    Department of Orthopaedic Surgery, Tohoku University School of Medicine, Sendai, Japan
    J Neurosurg Spine 7:587-93. 2007
    ..The authors analyzed a series of 118 cases of spinal dumbbell tumors to elucidate the feature of the tumors...
  40. ncbi Resection of thoracic dumbbell neurinomas: single postero-lateral approach or combined posterior and transthoracic approach?
    M Payer
    Department of Neurosurgery, University Hospital of Geneva, 24 Rue Micheli du Crest, 1211 Geneva 14, Switzerland
    J Clin Neurosci 13:690-3. 2006
    ..We report the removal of a dumbbell neurinoma at T6/7 using a single posterior midline approach with laminectomy and costo-transversectomy and review the literature regarding the approaches to thoracic dumbbell tumours.
  41. ncbi Acute nontraumatic spinal epidural hematomas. An important differential diagnosis in spinal emergencies
    C Alexiadou Rudolf
    Department of Neurosurgery, University of Cologne, Germany
    Spine (Phila Pa 1976) 23:1810-3. 1998
    ..CONCLUSIONS: The results of the current series demonstrate both the superiority of magnetic resonance imaging for diagnosis of SSEH as well as the necessity of early decompressive surgery in cases of sensorimotor paralysis after SSEH...
  42. ncbi Outcome after less-invasive decompression of lumbar spinal stenosis: a randomized comparison of unilateral laminotomy, bilateral laminotomy, and laminectomy
    Claudius Thome
    Department of Neurosurgery, University Hospital Mannheim, Faculty for Clinical Medicine of the Karl Ruprecht University of Heidelberg, Mannheim, Germany
    J Neurosurg Spine 3:129-41. 2005
    Recently, limited decompression procedures have been proposed in the treatment of lumbar stenosis. The authors undertook a prospective study to compare the safety and outcome of unilateral and bilateral laminotomy with laminectomy.
  43. ncbi Occipitocervical fusion with C1 laminectomy in children
    T Nakagawa
    Department of Orthopaedic Surgery, Faculty of Medicine, Kagoshima University, Japan
    Spine (Phila Pa 1976) 22:1209-14. 1997
    ..This surgery induced no apparent postoperative spinal deformations...
  44. ncbi Comparison of spinal and general anesthesia in lumbar laminectomy surgery: a case-controlled analysis of 400 patients
    Robert F McLain
    The Cleveland Clinic Spine Institute, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    J Neurosurg Spine 2:17-22. 2005
    ..Application of regional anesthetics is widely preferred for lower-extremity surgery, but general anesthesia is used almost exclusively in spine surgery, despite evidence that spinal anesthesia is as safe and may offer some advantages...
  45. ncbi Minimally invasive resection of intradural-extramedullary spinal neoplasms
    Trent L Tredway
    Department of Neurosurgery, University of Washington, Seattle, Washington, USA
    Neurosurgery 58:ONS52-8; discussion ONS52-8. 2006
    ..Traditional treatment of these tumors includes open laminectomy with intradural resection...
  46. ncbi Minimum 10-year outcome of decompressive laminectomy for degenerative lumbar spinal stenosis
    T Iguchi
    Department of Orthopaedic Surgery, Kobe Rosai Hospital, Kobe, Japan
    Spine (Phila Pa 1976) 25:1754-9. 2000
    STUDY DESIGN: A retrospective follow-up study was conducted in patients who underwent decompressive laminectomy for degenerative lumbar spinal stenosis...
  47. ncbi Doublecortin expression levels in adult brain reflect neurogenesis
    Sebastien Couillard-Despres
    Volkswagen Foundation Junior Group, University of Regensburg, Franz Josef Strauss Allee 11, 93053 Regensburg, Germany
    Eur J Neurosci 21:1-14. 2005
    ....
  48. ncbi Surgical or nonoperative treatment for lumbar spinal stenosis? A randomized controlled trial
    Antti Malmivaara
    Finnish Office for Health Technology Assessment, National Research and Development Center, FinOHTA Stakes, Helsinki, Finland
    Spine (Phila Pa 1976) 32:1-8. 2007
    ..A randomized controlled trial...
  49. ncbi Laminoplasty and skip laminectomy for cervical compressive myelopathy: range of motion, postoperative neck pain, and surgical outcomes in a randomized prospective study
    Yasutsugu Yukawa
    Department of Orthopedic Surgery, Chubu Rosai Hospital, Nagoya, Japan
    Spine (Phila Pa 1976) 32:1980-5. 2007
    ..A prospective randomized clinical trial in surgical treatment for cervical compressive myelopathy...
  50. ncbi Safety and efficacy of intradural extramedullary spinal tumor removal using a minimally invasive approach
    Richard J Mannion
    Department of Neurosurgery, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia
    Neurosurgery 68:208-16; discussion 216. 2011
    ..of less postoperative pain, a quicker recovery, and the avoidance of long-term instability from multilevel laminectomy, there are concerns over whether one can safely and effectively remove intradural extramedullary tumors in a ..
  51. ncbi A segmental partial laminectomy for cervical spondylotic myelopathy: anatomical basis and clinical outcome in comparison with expansive open-door laminoplasty
    Koji Otani
    Department of Orthopaedic Surgery, Fukushima Medical University School of Medicine, Fukushima City, Japan
    Spine (Phila Pa 1976) 34:268-73. 2009
    ..A comparative study regarding the clinical outcome of the 2-different surgical procedures for patients with cervical spondylotic myelopathy (CSM)...
  52. ncbi The source of axial pain after cervical laminoplasty-C7 is more crucial than deep extensor muscles
    Noboru Hosono
    Department of Orthopedic Surgery, Osaka Kosei Nenkin Hospital, Osaka, Japan
    Spine (Phila Pa 1976) 32:2985-8. 2007
    ..Prospective study to investigate the incidence of axial pain in the 3 different procedures of laminoplasty...
  53. ncbi Results of skip laminectomy-minimum 2-year follow-up study compared with open-door laminoplasty
    Tateru Shiraishi
    Department of Orthopaedic Surgery, Saiseikai Utsunomiya Hospital, Tochigi, Japan
    Spine (Phila Pa 1976) 28:2667-72. 2003
    Results of skip laminectomy and open-door laminoplasty for cervical spondylotic myelopathy were compared.
  54. pmc Spinal stenosis re-operation rate in Sweden is 11% at 10 years--a national analysis of 9,664 operations
    Karl Ake Jansson
    Department of Orthopedics, Karolinska University Hospital Solna, 171 76 Stockholm, Sweden
    Eur Spine J 14:659-63. 2005
    ..The 1-, 2-, 5-, and 10-year re-operation rates were 2, 5, 8 and 11%, respectively. The rate lowered by 31% over time. Adding a fusion may lower the re-operation risk, an observation which can only be evaluated in randomised trial...
  55. ncbi A preclinical post laminectomy rat model mimics the human post laminectomy syndrome
    Jennifer B Massie
    Department of Orthopaedics, Veterans Administration San Diego Health Care System and University of California, 3350 La Jolla Village Drive, San Diego, CA 92161, USA
    J Neurosci Methods 137:283-9. 2004
    Chronic low back pain with sciatica complicating post laminectomy surgery is poorly understood...
  56. ncbi Single stage complete excision of large thoracic dumbbell schwannoma by modified posterior approach
    Amit Agrawal
    Department of Surgery, Datta Meghe Institute of Medical Sciences, Wardha 442005 Maharashtra, India
    Surg Neurol 70:432-6. 2008
    ..Successful management of posterior mediastinal dumbbell tumors depends on complete resection with adequate exposure...
  57. ncbi Lumbar laminectomy alone or with instrumented or noninstrumented arthrodesis in degenerative lumbar spinal stenosis. Patient selection, costs, and surgical outcomes
    J N Katz
    Department of Medicine, Brigham and Women s Hospital, Boston, Massachusetts, USA
    Spine (Phila Pa 1976) 22:1123-31. 1997
    ..OBJECTIVES: 1) Identify correlates of the decision to perform arthrodesis in patients undergoing laminectomy for lumbar spinal stenosis...
  58. ncbi Spinal column deformity and instability after lumbar or thoracolumbar laminectomy for intraspinal tumors in children and young adults
    P J Papagelopoulos
    Department of Orthopedics, Mayo Clinic, Rochester, Minnesota, USA
    Spine (Phila Pa 1976) 22:442-51. 1997
    ..about the occurrence of spinal column deformity or instability after multilevel lumbar or thoracolumbar total laminectomy for removal of benign intraspinal tumors in children and young adults...
  59. pmc Operative treatment of cervical spondylotic myelopathy and radiculopathy. A comparison of laminectomy and laminoplasty at five year average follow-up
    S B Kaminsky
    Department of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, IA 52246, USA
    Iowa Orthop J 24:95-105. 2004
    ..The operative treatment for patients with moderate to severe involvement is decompression of the spinal cord. Laminectomy has been a traditional approach and laminoplasty has developed as an attractive alternative...
  60. ncbi Effects of age and comorbidities on complication rates and adverse outcomes after lumbar laminectomy in elderly patients
    Gordon Li
    Department of Neurosurgery, Stanford University School of Medicine, Stanford, CA, USA
    Spine (Phila Pa 1976) 33:1250-5. 2008
    ..This is a retrospective cohort study using the National Inpatient Sample database...
  61. ncbi Treatment of intramedullary spinal cysticercosis: report of 2 cases and review of literature
    Faiz Uddin Ahmad
    Department of Neurosurgery, Neurosciences Centre, All India Institute of Medical Sciences, New Delhi 110029, India
    Surg Neurol 67:74-7; discussion 77. 2007
    ..NCC, Taenia solium involvement in the central nervous system, is one of the most common parasitic diseases. Spinal IMC is one of the rarest forms of NCC...
  62. ncbi Traumatic spinal cord injury produced by controlled contusion in mouse
    L B Jakeman
    Department of Physiology and Cell Biology, College of Medicine and Public Health, Ohio State University, Columbus, USA
    J Neurotrauma 17:299-319. 2000
    ..the mid-thoracic spinal cord is subjected to a single rapid and calibrated displacement at the site of a dorsal laminectomy. Injury is initiated at the tip of a vertical shaft driven by an electromagnetic shaker...
  63. ncbi Bilateral traumatic neuroma of the anterior cervical nerve root: case report
    Fuat Torun
    Department of Neurosurgery, Selcuk University, Konya, Turkey
    Spine (Phila Pa 1976) 30:E521-3. 2005
    ..Case report...
  64. ncbi Surgical management of cervical spondylotic myelopathy with laminectomy and instrumented fusion
    Beril Gok
    Department of Neurosurgery, Johns Hopkins University, Baltimore, MD 21287, USA
    Neurol Res 31:1097-101. 2009
    The indications for treating cervical spondylotic myelopathy (CSM) with laminectomy and instrumented fusion remain ill-defined...
  65. ncbi Biomechanical effects of C2-C7 intersegmental stability due to laminectomy with unilateral and bilateral facetectomy
    Ng Hong-Wan
    School of Mechanical and Production Engineering, Nanyang Technological University, Singapore
    Spine (Phila Pa 1976) 29:1737-45; discussion 1746. 2004
    The biomechanical responses resulting from laminectomy with graded unilateral and bilateral facetectomy were quantified using a three-dimensional nonlinear finite element model of the C2-C7 motion segments.
  66. ncbi Laminectomy and posterior cervical plating for multilevel cervical spondylotic myelopathy and ossification of the posterior longitudinal ligament: effects on cervical alignment, spinal cord compression, and neurological outcome
    John K Houten
    Department of Neurosurgery, New York University School of Medicine, New York, New York 10016, USA
    Neurosurgery 52:1081-7; discussion 1087-8. 2003
    ..We theorized that laminectomy and stabilization of the cervical spine with lateral mass plates would obviate the disadvantages of anterior ..
  67. ncbi ERK2 small interfering RNAs prevent epidural fibrosis via the efficient inhibition of collagen expression and inflammation in laminectomy rats
    Chao Zhang
    Department of Orthopedics, Tianjin Medical University General Hospital, Tianjin 300052, China
    Biochem Biophys Res Commun 444:395-400. 2014
    b>Laminectomy is a widely accepted treatment for lumbar disorders. Epidural Fibrosis (EF) is a common post-laminectomy or post-discectomy complication, which is thought to cause recurrent pain...
  68. ncbi Effect of multilevel open-door laminoplasty and laminectomy on flexibility of the cervical spine: an experimental investigation
    Swathi Kode
    Department of Biomedical Engineering, The University of Iowa, Iowa City, IA, USA
    Spine (Phila Pa 1976) 37:E1165-70. 2012
    A biomechanical comparison of 2 commonly used posterior surgical procedures for spinal cord decompression in the cervical spine: laminoplasty (open door) and laminectomy.
  69. ncbi Ossification of the ligamentum flavum of the thoracic spine in the Korean population
    Kyung Chung Kang
    Department of Orthopaedic Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Kangnam Gu, Seoul, Korea
    J Neurosurg Spine 14:513-9. 2011
    ..It is seen mostly in East Asia, although the majority of reports have issued from Japan. In the present study, the clinical features and prognostic factors of thoracic OLF were examined in a large number of Korean patients...
  70. ncbi Biomechanical comparison of facet-sparing laminectomy and Christmas tree laminectomy
    Paul W Detwiler
    Division of Neurological Surgery, Spinal Biomechanics Research Laboratory, Barrow Neurological Institute, Phoenix, Arizona 5013 4496, USA
    J Neurosurg 99:214-20. 2003
    The authors compared differences in biomechanical stability between two decompressive laminectomy techniques for treating lumbar stenosis...
  71. ncbi Comparison of efficacy of dexketoprofen versus paracetamol on postoperative pain and morphine consumption in laminectomy patients
    Elvin Kesimci
    Department of Anaesthesiology and Reanimation, Ataturk Training and Research Hospital, Ankara, Turkey
    Agri 23:153-9. 2011
    ....
  72. pmc Sudden onset of paraplegia caused by hemorrhagic spinal epidural angiolipoma. A case report
    Ali Akhaddar
    Department of Neurosurgery, Mohammed V Military Teaching Hospital, University of King Mohammed V Souissi, Rabat, Morocco
    Eur Spine J 17:S296-8. 2008
    ..A bilateral T2-T4 laminectomy was performed to achieve resection of a lipomatous tumor containing area of spontaneous hemorrhage...
  73. ncbi Clinical and functional outcomes of laminoplasty and laminectomy
    Julian Hardman
    Department of Neurosurgery, School of Medicine, University of Illinois at Chicago, Chicago, IL, USA
    Neurol Res 32:416-20. 2010
    Laminoplasty has become a common alternative to laminectomy for cervical spondylotic myelopathy or radiculopathy. The procedures have been compared before, but data on functional recovery are limited...
  74. ncbi The extent of laminectomy affects pain-related behavior in a rat model of neuropathic pain
    Vana Kosta
    Department of Anatomy, Histology and Embryology, University of Split Medical School, Split, Croatia
    Eur J Pain 13:243-8. 2009
    ..We tested the hypothesis that laminectomy performed during ganglionectomy induces lumbar column deformity...
  75. ncbi Unilateral limited laminectomy as the approach of choice for the removal of thoracolumbar neurofibromas
    Alfredo Pompili
    Division of Neurosurgery, Regina Elena National Cancer Institute, Rome, Italy
    Spine (Phila Pa 1976) 29:1698-702. 2004
    ..The paper reports a minimally invasive approach to the dorsolumbar spine for the removal of neurofibromas...
  76. pmc Unilateral hemilaminectomy for patients with intradural extramedullary tumors
    Cai Xing Sun
    Zhejiang Traditional Medical University, Hangzhou 310009, China
    J Zhejiang Univ Sci B 12:575-81. 2011
    ....
  77. ncbi Minimally invasive cervical microendoscopic laminoforaminotomy
    Domagoj Coric
    Carolina Neurosurgery and Spine Associates, Charlotte, North Carolina 28207, USA
    Neurosurg Focus 25:E2. 2008
    ..The authors present a modified surgical technique for posterior MELF as well as a case study illustrating its synergy with anterior arthroplasty...
  78. ncbi Laminectomy membrane formation in dogs: is the answer still elusive?
    Kate Chandler
    Vet J 172:1-2. 2006
  79. ncbi A mapping study of caspase-3 activation following acute spinal cord contusion in rats
    Melanie L McEwen
    Department of Physical Medicine and Rehabilitation, University of Kentucky Medical Center, Cardinal Hill Rehabilitation Hospital, 800 Rose St, MN 225, Lexington, KY 40536 0298, USA
    J Histochem Cytochem 53:809-19. 2005
    ..This time-course study provides a framework for investigating and understanding the different signaling events contributing to this biphasic pattern of caspase-3 activation...
  80. ncbi Health outcome assessment before and after lumbar laminectomy for radiculopathy
    T J Albert
    Rothman Institute, Philadelphia, Pennsylvania, USA
    Spine (Phila Pa 1976) 21:960-2; discussion 963. 1996
    STUDY DESIGN. Forty-one patients undergoing lumbar laminectomy for radiculopathy resulting from herniated discs assessed their health status using a generic health outcome instrument (Medical Outcomes Study Short Form 36) before surgery ..
  81. ncbi Treatment of cervical stenotic myelopathy: a cost and outcome comparison of laminoplasty versus laminectomy and lateral mass fusion
    Jason M Highsmith
    Department of Neurosurgery, Emory University, Atlanta, Georgia, USA
    J Neurosurg Spine 14:619-25. 2011
    ..or ossification of the posterior longitudinal ligament is often treated with laminoplasty or cervical laminectomy (with fusion)...
  82. ncbi Minimally invasive microsurgical treatment of cervical intraspinal extramedullary tumors
    Yong Yu
    Department of Neurosurgery, Zhongshan Hospital, Fudan University, 180 Fenglin Road, Shanghai 200032, China
    J Clin Neurosci 18:1168-73. 2011
    Removal of intraspinal tumors by the classic posterior midline approach with laminectomy may cause damage to and instability of cervical segments...
  83. ncbi Vertebral stabilization using positively threaded profile pins and polymethylmethacrylate, with or without laminectomy, for spinal canal stenosis and vertebral instability caused by congenital thoracic vertebral anomalies
    Takeshi Aikawa
    Aikawa Veterinary Medical Center, Tokyo, Japan
    Vet Surg 36:432-41. 2007
    ..To describe diagnostic findings, surgical technique, and outcome in dogs with thoracic spinal canal stenosis and vertebral instability secondary to congenital vertebral anomalies...
  84. ncbi Spinal intradural juxtamedullary cysts in the adult: surgical management and outcome
    Hischam Bassiouni
    Department of Neurosurgery, University Hospital Essen, Essen, Germany
    Neurosurgery 55:1352-9; discussion 1359-60. 2004
    ..We retrospectively analyzed a series of patients harboring this entity with regard to clinical and radiological features, surgical management, and follow-up results...
  85. ncbi Effects of angle and laminectomy on triangulated pedicle screws
    Cumhur Kilincer
    Department of Neurosurgery, Trakya University Medical Faculty, Edirne, Turkey
    J Clin Neurosci 14:1186-91. 2007
    We aimed to demonstrate the effect of angle and laminectomy on paired pedicle screws to determine whether a 90 degrees screw angle is optimal as has been previously suggested...
  86. ncbi Skip laminectomy and laminoplasty for cervical spondylotic myelopathy: a prospective study of clinical and radiologic outcomes
    Alagappan Sivaraman
    Royal National Orthopaedic Hospital, Stanmore, London, UK
    J Spinal Disord Tech 23:96-100. 2010
    ..A prospective nonrandomized study comparing the outcomes of the 2 surgical techniques used in the treatment of cervical spondylotic myelopathy...
  87. ncbi Short-term progressive spinal deformity following laminoplasty versus laminectomy for resection of intradural spinal tumors: analysis of 238 patients
    Matthew J McGirt
    Department of Neurosurgery, Johns Hopkins School of Medicine, Baltimore, Maryland, USA
    Neurosurgery 66:1005-12. 2010
    ..We set out to determine whether the use of laminoplasty (LP) vs laminectomy (LM) has reduced the incidence of subsequent spinal deformity following intradural tumor resection at our ..
  88. ncbi A comparison of posterolateral lumbar fusion comparing autograft, autogenous laminectomy bone with bone marrow aspirate, and calcium sulphate with bone marrow aspirate: a prospective randomized study
    Chi Chien Niu
    Department of Orthopaedic Surgery, Chang Gung Memorial Hospital, Chang Gung University College of Medicine, Taoyuan, Taiwan
    Spine (Phila Pa 1976) 34:2715-9. 2009
    ..A prospective clinical study...
  89. pmc Torsion biomechanics of the spine following lumbar laminectomy: a human cadaver study
    Arno Bisschop
    Department of Orthopedic Surgery, Research Institute MOVE, VU University Medical Center, De Boelelaan 1117, PO Box 7057, 1081 HV Amsterdam, The Netherlands
    Eur Spine J 22:1785-93. 2013
    Lumbar laminectomy affects spinal stability in shear loading. However, the effects of laminectomy on torsion biomechanics are unknown...
  90. ncbi Outcomes after laminoplasty compared with laminectomy and fusion in patients with cervical myelopathy: a systematic review
    S Tim Yoon
    Department of Orthopedics, Emory Spine Center, Atlanta, GA Spectrum Research, Inc, Tacoma, WA Department of Neurology and Orthopaedic Surgery, University of Virginia, Charlottesville, VA and Washington University Orthopedics, One Barnes Jewish Hospital Plaza, St Louis, MO
    Spine (Phila Pa 1976) 38:S183-94. 2013
    ..Systematic review...
  91. pmc Design of Lamifuse: a randomised, multi-centre controlled trial comparing laminectomy without or with dorsal fusion for cervical myeloradiculopathy
    Ronald Hma Bartels
    Department of Neurosurgery, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    BMC Musculoskelet Disord 8:111. 2007
    b>laminectomy is a valuable surgical treatment for some patients with a cervical radiculomyelopathy due to cervical spinal stenosis...
  92. ncbi Post-laminectomy cerebrospinal fluid fistula treated with epidural blood patch
    N F Maycock
    Department of Anaesthesia, Queen Elizabeth Hospital, Adelaide, South Australia
    Spine (Phila Pa 1976) 19:2223-5. 1994
    ..CONCLUSIONS. The techniques involved in performing a blood patch after spinal surgery may well differ from those usually recommended in the management of spinal headache resulting from other causes of dural puncture...
  93. pmc The impact of bone mineral density and disc degeneration on shear strength and stiffness of the lumbar spine following laminectomy
    Arno Bisschop
    Department of Orthopedic Surgery, Research Institute MOVE, VU University Medical Center, De Boelelaan 1117, P O Box 7057, 1081 HV, Amsterdam, The Netherlands
    Eur Spine J 21:530-6. 2012
    b>Laminectomy is a standard surgical procedure for elderly patients with symptomatic degenerative lumbar stenosis...
  94. ncbi Effect of the Total Facet Arthroplasty System after complete laminectomy-facetectomy on the biomechanics of implanted and adjacent segments
    Frank M Phillips
    Rush University Medical Center, Chicago, IL, USA
    Spine J 9:96-102. 2009
    ..The Total Facet Arthroplasty System (TFAS) is a motion-restoring implant suggested as an alternative to rigid fixation after complete facetectomy...
  95. ncbi Posterior cervical decompressive laminectomy and lateral mass screw fixation
    Ziad A Audat
    Departments of Orthopedics, King Abdullah University Hospital, Faculty of Medicine, Jordan University of Science and Technology, Irbid, Jordan
    Neurosciences (Riyadh) 16:248-52. 2011
    To review the results and complications of cervical decompressive laminectomy and lateral mass screw fixation.
  96. pmc Surgical versus nonsurgical treatment for lumbar degenerative spondylolisthesis
    James N Weinstein
    Department of Orthopaedics, Dartmouth Medical School, Lebanon, NH, USA
    N Engl J Med 356:2257-70. 2007
    ..Management of degenerative spondylolisthesis with spinal stenosis is controversial. Surgery is widely used, but its effectiveness in comparison with that of nonsurgical treatment has not been demonstrated in controlled trials...
  97. pmc Preserving the C7 spinous process in laminectomy combined with lateral mass screw to prevent axial symptom
    Peng Zhang
    Department of Spine Surgery, The Third Hospital of Hebei Medical University, 139 Ziqiang Road, 050051, Shijiazhuang, China
    J Orthop Sci 16:492-7. 2011
    ..Some patients underwent laminectomy and fixation developed the symptom...
  98. ncbi Dorsal surgery for myelopathy and myeloradiculopathy
    Gregory C Wiggins
    Department of Neurosurgery, David Grant Medical Center, Travis Air Force Base, California 94535 1800, USA
    Neurosurgery 60:S71-81. 2007
    ..To review the dorsal approaches to the cervical spine for myelopathy and myeloradiculopathy...
  99. ncbi Fibromatosis of the cervical region following laminectomy: a case report and literature review
    Shruti Sevak
    Michigan State University College of Human Medicine, Grand Rapids, MI, USA
    Spine (Phila Pa 1976) 37:E456-9. 2012
    ..A case report and a discussion of recently published data...
  100. ncbi Spinal pseudomeningoceles and cerebrospinal fluid fistulas
    Daniel Couture
    Department of Neurosurgery, Wake Forest University School of Medicine, Winston Salem, North Carolina 27157 1029, USA
    Neurosurg Focus 15:E6. 2003
    ..Nonsurgical methods may be used, but more frequently operative repair is required. In this article, the authors review the diagnosis and treatment of spinal pseudomeningoceles and CSF fistulas...
  101. ncbi The effect of methylene blue on peridural fibrosis formation after laminectomy in rats: an experimental novel study
    Majid Reza Farrokhi
    Department of Neurosurgery, Shiraz Neurosciences Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
    Spine J 11:147-52. 2011
    ..Recently, attention has been focused on peridural fibrosis (PF), which may be responsible for recurrent pain after laminectomy or discectomy. Methylene blue (MB) has been shown to prevent fibrosis formation in various tissues.

Research Grants38

  1. Neural Prosthetic Control of Continence and Micturition
    Warren M Grill; Fiscal Year: 2013
    ..from prior approaches using electrical stimulation of the spinal roots in that it does not require a spinal laminectomy, does not require irreversible surgical transection of the sacral sensory nerve roots, and stimulates the ..
  2. Device for Surgical Adhesion Prevention
    REKHA BANSAL; Fiscal Year: 2010
    ..the feasibility of using NM2040 as a treatment to prevent surgical adhesions using a validated lumbar spine laminectomy model;2) to develop a surgical adhesion model for gynecological adhesions for which good clinical endpoint ..
  3. Air Barrier System to reduce contamination of wounds during surgery
    SEAN SELF; Fiscal Year: 2013
    ..procedures, presenting high infection risk, in orthopedics (total hip arthroplasty), neurosurgery (lumbar laminectomy with instrumented fusion), and vascular surgery (femoral-popliteal bypass grafting) have been selected for ..
  4. An injectable biocompatible hydrogel nucleus pulposus replacement
    Gavin Braithwaite; Fiscal Year: 2009
    ..Although commonly prescribed, moderately invasive surgical solutions such as discectomy and laminectomy, and more invasive solutions such as intervertebral fusion and total disc replacement have important problems ..
  5. BACK PAIN OUTCOME ASSESSMENT TEAM
    Richard Deyo; Fiscal Year: 1991
    ..lumbar spine surgery will include a methodologic review and synthesis of existing literature on the outcomes of laminectomy, discectomy, and fusion...
  6. FORE-SCI TRAINING PROGRAM (RFP 08-01)
    DANA MCTIGUE; Fiscal Year: 2011
    ..Participants in this program will receive in depth hands-on laboratory training in: Thoracic and cervical laminectomy surgeries, spinal contusion and transection injuries in rats and mice, operating spinal contusion injury ..
  7. FORE-SCI TRAINING PROGRAM (RFP 08-01)
    Dana M McTigue; Fiscal Year: 2009
    ..Participants in this program will receive in depth hands-on laboratory training in: Thoracic and cervical laminectomy surgeries, spinal contusion and transection injuries in rats and mice, operating spinal contusion injury ..
  8. FORE-SCI TRAINING PROGRAM (RFP 08-01)
    DANA MCTIGUE; Fiscal Year: 2012
    ..Participants in this program will receive in depth hands-on laboratory training in: Thoracic and cervical laminectomy surgeries, spinal contusion and transection injuries in rats and mice, operating spinal contusion injury ..
  9. Voltage gated sodium channels in acute post laminectomy pain
    CHRISTINA MARIE SPOFFORD; Fiscal Year: 2013
    ..We plan to develop and validate a new model of acute post laminectomy pain that will allow for clinically relevant pain behaviors to be identified...
  10. A Novel Approach to Prevent Periduaral Fibrosis
    James Pachence; Fiscal Year: 2001
    ..For instance, after laminectomy, fibrotic scarring can develop in both the epidural region and arachnoid spaces, producing recurring pain and ..
  11. BIOELASTIC MATERIAL TO PREVENT POST-LAMINECTOMY ADHESION
    Jie Xu; Fiscal Year: 2001
    ..demonstrated both materials to be highly effective in preventing adhesions to the spinal dura in the rabbit laminectomy model...
  12. Are Fibromyalgia and Chiari I Malformation Related?
    Dedra Buchwald; Fiscal Year: 2005
    ..The overall safety and efficacy of the most common approach, a posterior fossa craniectomy and cervical laminectomy to expand the posterior fossa volume, is well supported in the literature...
  13. Neural Prosthetic Control of Continence and Micturition
    WARREN GRILL; Fiscal Year: 2003
    ..from existing approaches using electrical stimulation of the spinal roots in that it does not require a spinal laminectomy, does not require irreversible surgical transection of the sacral sensory nerve roots, and stimulates the ..
  14. RADIOTHERAPY--PREVENT FIBROSIS AFTER LUMBAR LAMINECTOMY
    Peter Gerszten; Fiscal Year: 2001
    ..studies investigating in both rat and dog models showed a significant reduction in peridural fibrosis after laminectomy using low dose external beam radiation (700 cGy) given 24 hours prior to surgery...
  15. Preventing Post-Laminectomy Peridural Fibrosis
    Weiliam Chen; Fiscal Year: 2008
    ..scar tissue is part of the normal healing process and also an unavoidable consequence of procedures involving laminectomy. Epidural scar formation can result in fibrous adhesions around nerve roots imposing tension by entrapping the ..
  16. Incidence & Outcomes of SSI After Breast Cancer Surgery
    Margaret Olsen; Fiscal Year: 2008
    ....
  17. ANESTHETIC EFFECTS ON SENSORIMOTOR INTEGRATION
    JOSEPH ANTOGNINI; Fiscal Year: 2009
    ..Understanding how and where anesthetics act will eventually lead to the development of better and safer anesthetics, thereby decreasing peri-operative morbidity and mortality and improving public health. ..
  18. CALPAIN ACTIVATION OF T CELLS IN DEMYELINATING DISEASE
    Naren Banik; Fiscal Year: 2009
    ..Understanding the mechanisms may help develop therapeutic strategies (e.g., calpain as a target) for treatment of MS. ..
  19. EXPIRATORY MUSCLE ACTIVATION TO PRODUCE COUGH
    Anthony DiMarco; Fiscal Year: 2003
    ..Restoration of affective cough mechanism may allow patients with spinal cord injury to clear secretions more easily, reduce the incidence of respiratory complication and, ultimately, improve their life quality. ..
  20. Attenuation of Axonal Damage and Neuronal Death in EAE
    Naren L Banik; Fiscal Year: 2010
    ..abstract_text> ..
  21. CALPAIN IN THE PATHOPHYSIOLOGY OF DEMYELINATING DISEASE
    Naren Banik; Fiscal Year: 2003
    ....
  22. Spinal Cord Stimulation to Restore Cough In Humans
    Anthony DiMarco; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  23. Improving diabetes outcomes: A couples intervention
    Paula Trief; Fiscal Year: 2006
    ..As an R34, this is a pilot proposal to develop preliminary data on the feasibility and efficacy of he couples approach so that a future full-scale trial may be submitted as an R18 proposal. ..
  24. Genes Controlling the Renal Handling of Phosphate
    Ralph Meyer; Fiscal Year: 2004
    ..Such intervention may improve the skeletal symptoms of patients with hypophosphatemic bone disease and improve their quality of life. ..
  25. Indomethacin and p38 Regulating AP-1 In Heat Shock
    Jacob Locke; Fiscal Year: 2004
    ..abstract_text> ..
  26. Combined Intercostal and Diaphragm Pacing
    Anthony DiMarco; Fiscal Year: 2004
    ....
  27. BRAIN AND SPINAL CORD CONTRIBUTIONS TO ANESTHETIC ACTION
    JOSEPH ANTOGNINI; Fiscal Year: 2005
    ..This information will aid the development of newer and safer anesthetics, as well as lead to clinically useful means of modulating the neurotransmitter systems that are themselves modulated by anesthetics. ..
  28. ANGIOTENSIN ANALOGS TO TREAT WOUND HEALING
    Kathleen Rodgers; Fiscal Year: 2005
    ..In this phase II SBIR, these compounds will undergo extensive preclinical testing to determine whether they should be further developed as a second generation of wound healing drugs. ..
  29. Polysomal RNA Antitumor Immunity
    John Chi; Fiscal Year: 2005
    ..Results from these experiments will help characterize the potential use of dendritic cells transfected with polysomal RNA in creating antigen specific tumor vaccines for brain tumors. ..
  30. Effect of vertebral endplate composition on disc health
    Frank Acosta; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  31. SPINAL CORD REPAIR WITH HUMAN UMBILICAL CORD BLOOD CELLS
    Samuel Saporta; Fiscal Year: 2003
    ..abstract_text> ..
  32. ESTROGEN EFFICACY IN SPINAL CORD INJURY
    Naren Banik; Fiscal Year: 2006
    ..Understanding estrogen's mechanisms in cell protection and recovery as it relates to multidestructive pathways will establish it as a viable SCI treatment agent. ..
  33. Oligodendrocyte Progenitors in Spinal Cord Injury Repair
    DANA MCTIGUE; Fiscal Year: 2006
    ..abstract_text> ..
  34. Prevention of Healthcare-Associated Drug-Resistant GNR
    Lisa Maragakis; Fiscal Year: 2006
    ..Maragakis with the skills she needs to develop into an independent clinical investigator in epidemiologic research for the prevention of healthcare-associated infections. ..
  35. Susceptibility Testing, Treatment Choices, and Outcomes of MDR-GNB Infections
    Lisa Maragakis; Fiscal Year: 2009
    ..This research is designed to better understand how providers use information from various microbiology laboratory testing methods to choose treatments and to identify strategies that lead to the best patient outcomes. ..
  36. A NEW PEDIATRIC MODEL OF ISCHEMIC STROKE IN PIGLETS
    John Kuluz; Fiscal Year: 2005
    ....
  37. Functional Health CAT in Diabetes
    Carolyn Schwartz; Fiscal Year: 2004
    ..abstract_text> ..