craniotomy

Summary

Summary: Any operation on the cranium or incision into the cranium. (Dorland, 28th ed)

Top Publications

  1. doi Intracerebral hemorrhage: getting ready for effective treatments
    Fred Rincon
    Department of Medicine, Division of Neurology and Critical Care, Cooper University Hospital, University of Medicine and Dentistry of New Jersey, Camden, New Jersey, USA
    Curr Opin Neurol 23:59-64. 2010
  2. pmc Outcome of contemporary surgery for chronic subdural haematoma: evidence based review
    R Weigel
    Department of Neurosurgery, University Hospital, Klinikum Mannheim, Mannheim, Germany
    J Neurol Neurosurg Psychiatry 74:937-43. 2003
  3. doi Operative intracranial infection following craniotomy
    Shervin R Dashti
    Division of Neurological Surgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona, USA
    Neurosurg Focus 24:E10. 2008
  4. ncbi Risk factors for neurosurgical site infections after craniotomy: a critical reappraisal of antibiotic prophylaxis on 4,578 patients
    A M Korinek
    Neuroanaesthesia Unit, Department of Anaesthesiology, Pitie Salpetriere Hospital, University of Paris VI, Paris, France
    Br J Neurosurg 19:155-62. 2005
  5. doi A comparison of the combination of aprepitant and dexamethasone versus the combination of ondansetron and dexamethasone for the prevention of postoperative nausea and vomiting in patients undergoing craniotomy
    Ashraf S Habib
    Duke University Medical Center, Box 3094, Durham, NC 27710, USA
    Anesth Analg 112:813-8. 2011
  6. doi Defining the "edge of the envelope": patient selection in treating complex sellar-based neoplasms via transsphenoidal versus open craniotomy
    Gabriel Zada
    Department of Neurosurgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosurg 114:286-300. 2011
  7. ncbi Image-guided craniotomy for cerebral metastases: techniques and outcomes
    Tze Ching Tan
    Department of Neurosurgery, Brigham and Women s Hospital, Department of Surgery, Harvard Medical School, Boston, Massachusetts 02215, USA
    Neurosurgery 53:82-9; discussion 89-90. 2003
  8. doi The management of primary chronic subdural haematoma: a questionnaire survey of practice in the United Kingdom and the Republic of Ireland
    T Santarius
    Department of Neurosurgery, Addenbrooke s Hospital, University of Cambridge, Cambridge, UK
    Br J Neurosurg 22:529-34. 2008
  9. ncbi Bedside twist drill craniostomy for chronic subdural hematoma: a comparative study
    Eric M Horn
    Division of Neurological Surgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, AZ 85013, USA
    Surg Neurol 65:150-3; discussion 153-4. 2006
  10. ncbi Chronic subdural haematoma: surgical treatment and outcome in 1000 cases
    Miguel Gelabert-Gonzalez
    Neurosurgical Service, Department of Surgery, Clinic Hospital of Santiago, University of Santiago de Compostela, La Choupana, 15706 Santiago de Compostela, Spain
    Clin Neurol Neurosurg 107:223-9. 2005

Research Grants

Detail Information

Publications301 found, 100 shown here

  1. doi Intracerebral hemorrhage: getting ready for effective treatments
    Fred Rincon
    Department of Medicine, Division of Neurology and Critical Care, Cooper University Hospital, University of Medicine and Dentistry of New Jersey, Camden, New Jersey, USA
    Curr Opin Neurol 23:59-64. 2010
    ..The purpose of this article is to review recent advances in the management of spontaneous intracerebral hemorrhage...
  2. pmc Outcome of contemporary surgery for chronic subdural haematoma: evidence based review
    R Weigel
    Department of Neurosurgery, University Hospital, Klinikum Mannheim, Mannheim, Germany
    J Neurol Neurosurg Psychiatry 74:937-43. 2003
    ..To evaluate the results of surgical treatment options for chronic subdural haematoma in contemporary neurosurgery according to evidence based criteria...
  3. doi Operative intracranial infection following craniotomy
    Shervin R Dashti
    Division of Neurological Surgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona, USA
    Neurosurg Focus 24:E10. 2008
    ..They focused their review on those patients who required repeated surgery to treat the infection...
  4. ncbi Risk factors for neurosurgical site infections after craniotomy: a critical reappraisal of antibiotic prophylaxis on 4,578 patients
    A M Korinek
    Neuroanaesthesia Unit, Department of Anaesthesiology, Pitie Salpetriere Hospital, University of Paris VI, Paris, France
    Br J Neurosurg 19:155-62. 2005
    ..During period B, prophylaxis was given to every craniotomy. The effect of prophylaxis on craniotomy infections, independently of other risk factors, was studied by ..
  5. doi A comparison of the combination of aprepitant and dexamethasone versus the combination of ondansetron and dexamethasone for the prevention of postoperative nausea and vomiting in patients undergoing craniotomy
    Ashraf S Habib
    Duke University Medical Center, Box 3094, Durham, NC 27710, USA
    Anesth Analg 112:813-8. 2011
    Postoperative nausea and vomiting (PONV) occur commonly after craniotomy. In patients receiving prophylaxis with ondansetron and dexamethasone, vomiting occurred in 45% of patients at 48 hours...
  6. doi Defining the "edge of the envelope": patient selection in treating complex sellar-based neoplasms via transsphenoidal versus open craniotomy
    Gabriel Zada
    Department of Neurosurgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    J Neurosurg 114:286-300. 2011
    ....
  7. ncbi Image-guided craniotomy for cerebral metastases: techniques and outcomes
    Tze Ching Tan
    Department of Neurosurgery, Brigham and Women s Hospital, Department of Surgery, Harvard Medical School, Boston, Massachusetts 02215, USA
    Neurosurgery 53:82-9; discussion 89-90. 2003
    ....
  8. doi The management of primary chronic subdural haematoma: a questionnaire survey of practice in the United Kingdom and the Republic of Ireland
    T Santarius
    Department of Neurosurgery, Addenbrooke s Hospital, University of Cambridge, Cambridge, UK
    Br J Neurosurg 22:529-34. 2008
    ..The current literature provides Class II and III evidence and there is a need for randomized studies to address the role of external drainage, steroids and postoperative bed rest...
  9. ncbi Bedside twist drill craniostomy for chronic subdural hematoma: a comparative study
    Eric M Horn
    Division of Neurological Surgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, AZ 85013, USA
    Surg Neurol 65:150-3; discussion 153-4. 2006
    Although the bedside twist drill craniostomy is used to treat chronic subdural hematomas, the efficacy of this technique has not been compared with that of standard treatments (operative bur hole or craniotomy).
  10. ncbi Chronic subdural haematoma: surgical treatment and outcome in 1000 cases
    Miguel Gelabert-Gonzalez
    Neurosurgical Service, Department of Surgery, Clinic Hospital of Santiago, University of Santiago de Compostela, La Choupana, 15706 Santiago de Compostela, Spain
    Clin Neurol Neurosurg 107:223-9. 2005
    ..1980-2002) of the records of 1000 patients harbouring 1097 chronic subdural haematoma treated with burr-hole craniotomy with closed-system drainage was carried out...
  11. doi A comparative study of the patients with bilateral or unilateral chronic subdural hematoma: precipitating factors and postoperative outcomes
    Tai Hsin Tsai
    Department of Neurosurgery, Kaohsiung Medical University Hospital, Kaohsiung, Taiwan
    J Trauma 68:571-5. 2010
    ..The purpose of this study was to compare the clinical presentations, precipitating factors, computed tomography (CT) scan findings, postoperative complications, and outcomes between patients with bilateral and unilateral CSDH...
  12. doi Electroacupoint stimulation for postoperative nausea and vomiting in patients undergoing supratentorial craniotomy
    Xiao qiang Wang
    Department of Neurosurgery, Huashan Hospital of Fudan University, Shanghai, China
    J Neurosurg Anesthesiol 22:128-31. 2010
    We evaluated the effectiveness of transcutaneous electrical acupoint stimulation (TEAS) at the P6 acupoint for prevention of postoperative nausea and vomiting in patients undergoing supratentorial craniotomy.
  13. doi Wrong-site craniotomy: analysis of 35 cases and systems for prevention
    Fred L Cohen
    Gary Roberts and Associates, West Palm Beach, Florida, USA
    J Neurosurg 113:461-73. 2010
    The purpose of this case review was to identify and analyze existing wrong-site craniotomy (WSC) cases to determine the factors that contributed to the errors and to suggest preventative strategies for WSC...
  14. ncbi Craniotomy for supratentorial brain tumors: risk factors for brain swelling after opening the dura mater
    Mads Rasmussen
    Department of Neuroanesthesia, Arhus University Hospital, Arhus, Denmark
    J Neurosurg 101:621-6. 2004
    Cerebral swelling often occurs during craniotomy for cerebral tumors...
  15. doi The effects of P6 electrical acustimulation on postoperative nausea and vomiting in patients after infratentorial craniotomy
    Ming Xu
    Department of Anesthesiology, Huashan Hospital, Fudan University, Shanghai, China
    J Neurosurg Anesthesiol 24:312-6. 2012
    ..We evaluated the effectiveness of transcutaneous electrical acupoint stimulation (TEAS) at P6 for the prophylaxis of PONV in patients undergoing infratentorial craniotomy.
  16. doi Postoperative nausea and vomiting in patients after craniotomy: incidence and risk factors
    Björn Latz
    Klinik fur Anasthesiologie, Universitätsmedizin der Johannes Gutenberg Universität Mainz, Germany
    J Neurosurg 114:491-6. 2011
    ..of this study was to assess the incidence and risk factors of postoperative nausea and vomiting (PONV) after craniotomy because most available data about PONV in neurosurgical patients are retrospective in nature or derive from ..
  17. doi VEGF-releasing biodegradable nanospheres administered by craniotomy: a novel therapeutic approach in the APP/Ps1 mouse model of Alzheimer's disease
    Enara Herran
    NanoBioCel Group, Laboratory of Pharmaceutics, University of the Basque Country UPV EHU, School of Pharmacy, Vitoria, Spain
    J Control Release 170:111-9. 2013
    ..out in amyloid precursor protein/presenilin-1 (APP/Ps1) mice administering VEGF-NS through minimally invasive craniotomy. The results obtained showed that VEGF-NS were able to improve behavioral deficits, decrease Aβ deposits and ..
  18. doi A comparison of two doses of mannitol on brain relaxation during supratentorial brain tumor craniotomy: a randomized trial
    Charlotte Quentin
    Department of Anesthesiology, Montreal University Medical Centre, Montreal, Quebec, Canada
    Anesth Analg 116:862-8. 2013
    ..However, a dose-response relationship has not yet been established. In this study, we compared the effects of 0.7 and 1.4 g·kg(-1) mannitol on brain relaxation during elective supratentorial brain tumor surgery...
  19. ncbi Craniotomy for central nervous system metastases in epithelial ovarian carcinoma
    Bhavana Pothuri
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Gynecol Oncol 87:133-7. 2002
    ..Numerous series have reported various modalities for treatment with median survivals of 3 to 5 months, but the role of craniotomy has not been specifically addressed.
  20. doi Dural augmentation: part I-evaluation of collagen matrix allografts for dural defect after craniotomy
    Zachary N Litvack
    Department of Neurological Surgery, Oregon Health and Science University, Portland, Oregon 97239, USA
    Neurosurgery 65:890-7; discussion 897. 2009
    ..Our primary goal was to assess differences in the incidence of postoperative cerebrospinal fluid (CSF) leak, including fistula and pseudomeningocele, and postoperative infection between monolayer collagen and bilayer collagen grafts...
  21. ncbi Cranioplasty with individual carbon fibre reinforced polymere (CFRP) medical grade implants based on CAD/CAM technique
    W Saringer
    Department of Neurosurgery, University of Vienna, Medical School, Vienna, Austria
    Acta Neurochir (Wien) 144:1193-203. 2002
    ..The authors present a new method for the reconstruction of large or complex-formed cranial bone defects using prefabricated, computer-generated, individual CFRP (carbon fibre reinforced plastics) medical grade implants...
  22. ncbi Management of supratentorial cavernous malformations: craniotomy versus gammaknife radiosurgery
    Yang Hsin Shih
    Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, 201, Sec 2, Shi Pai Road, Taipei 112, Taiwan
    Clin Neurol Neurosurg 107:108-12. 2005
    Although craniotomy is the preferred treatment for symptomatic solitary supratentorial cavernous malformation (CM), radiosurgery is also an option...
  23. doi Microfibrillar collagen hemostat-induced necrotizing granulomatous inflammation developing after craniotomy: a pediatric case series
    Liat Apel-Sarid
    Department of Pathology and Laboratory Medicine, Division of Anatomic Pathology, Children s and Women s Health Centre of British Columbia, University of British Columbia, Vancouver, British Columbia, Canada
    J Neurosurg Pediatr 6:385-92. 2010
    ..According to the literature, MCH induces a very characteristic mixed inflammatory response that is rich in eosinophils; in light of these observations, many authors have suggested an allergy-based pathogenesis...
  24. doi Craniotomy for resection of meningioma in the elderly: a multicentre, prospective analysis from the National Surgical Quality Improvement Program
    Chirag G Patil
    Outcomes Research Lab, Palo Alto Veterans Health Care System, Palo Alto, California, USA
    J Neurol Neurosurg Psychiatry 81:502-5. 2010
    Whether there is an increased surgical risk in elderly patients who undergo craniotomy for meningioma resection remains a point of controversy...
  25. ncbi Neurological improvement after cranioplasty - analysis by transcranial doppler ultrasonography
    Jinn Rung Kuo
    Department of Neurosurgery, Chi Mei Medical Center, Tainan, Taiwan
    J Clin Neurosci 11:486-9. 2004
    ..We conclude that cranioplasty can improve neurological status, and it should be performed as earlier as edema has resolved...
  26. doi A comparison between sevoflurane and desflurane anesthesia in patients undergoing craniotomy for supratentorial intracranial surgery
    Giuseppina Magni
    Department of Anesthesia and Intensive Care, La Sapienza University, Policlinico Umberto I Roma, Rome, Italy
    Anesth Analg 109:567-71. 2009
    ..In this prospective clinical trial, we compared early postoperative recovery and cognitive function in patients undergoing craniotomy for supratentorial expanding lesions and receiving sevoflurane or desflurane anesthesia.
  27. ncbi The efficacy of 5-HT3 receptor antagonists for the prevention of postoperative nausea and vomiting after craniotomy: a meta-analysis
    Susan M Neufeld
    University of Alberta, Edmonton, Alberta, Canada
    J Neurosurg Anesthesiol 19:10-7. 2007
    ..After a systematic search, 7 published randomized placebo controlled trials involving 448 craniotomy patients (222 treatment, 226 control) were included in the meta-analysis...
  28. doi Neurosurgical craniotomy localization using a virtual reality planning system versus intraoperative image-guided navigation
    Axel T Stadie
    Neurochirurgische Klinik und Poliklinik, Universitätsmedizin Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany
    Int J Comput Assist Radiol Surg 6:565-72. 2011
    Accurate craniotomy placement is essential for frameless neuronavigation in minimally invasive neurosurgery. A craniotomy using virtual reality (VR) can be as accurate as neuronavigation.
  29. ncbi Hyperglycemia in patients administered dexamethasone for craniotomy
    Michael B Lukins
    Department of Anesthesia, Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, M5T 2S8, Canada
    Anesth Analg 100:1129-33. 2005
    ..study, we documented the blood glucose concentration changes for 12 h in 34 nondiabetic patients undergoing craniotomy and compared patients who received intraoperative dexamethasone (10 mg IV on induction and 4 mg IV 6 h later), ..
  30. ncbi Effect of clipping, craniotomy, or intravascular coiling on cerebral vasospasm and patient outcome after aneurysmal subarachnoid hemorrhage
    Brian L Hoh
    Neurosurgical Service, Endovascular Neurosurgery and Interventional Neuroradiology, and Cerebrovascular Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
    Neurosurgery 55:779-86; discussion 786-9. 2004
    ..We reviewed our experience over 8 years and assessed whether clipping, craniotomy, or coiling affects patient outcomes or the risk for vasospasm.
  31. ncbi Use of hinge craniotomy for cerebral decompression. Technical note
    John H Schmidt
    Department of Surgery, School of Medicine, West Virginia University Health Sciences Center, Charleston Division, USA
    J Neurosurg 107:678-82. 2007
    ..The authors developed a novel craniotomy technique using titanium bone plates in a hinged fashion, which maintains cerebral protection while reducing ..
  32. ncbi Relationship between drainage catheter location and postoperative recurrence of chronic subdural hematoma after burr-hole irrigation and closed-system drainage
    H Nakaguchi
    Department of Neurosurgery, Tokyo Kosei Nenkin Hospital, Tokyo, Japan
    J Neurosurg 93:791-5. 2000
    ..This study was conducted to determine the best position for the subdural drainage catheter to achieve a low recurrence rate after burr-hole irrigation and closed-system drainage of chronic subdural hematoma (CSDH)...
  33. doi Customised fabricated implants after previous failed cranioplasty
    Raymond C W Goh
    Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Chang Gung University, 5 Fu Shin Street, Kwei Shan, Taoyuan 333, Taiwan
    J Plast Reconstr Aesthet Surg 63:1479-84. 2010
    ..Customised fabricated alloplastic implants provide a safe, accurate and efficient way of restoring normal cranial contours in patients with cranial defects who have had previous failed cranioplasties...
  34. ncbi Taylored implants for alloplastic cranioplasty--clinical and surgical considerations
    B Hoffmann
    Neurosurgical Clinic, Clemenshospital Münster, Germany
    Acta Neurochir Suppl 93:127-9. 2005
    ..Application of this technique is limited by cost, nonetheless it is recommended for extensive reconstruction of the skull...
  35. ncbi Craniotomy for the resection of metastatic brain tumors in the U.S., 1988-2000: decreasing mortality and the effect of provider caseload
    Fred G Barker
    Brain Tumor Center, Neurosurgical Service, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Cancer 100:999-1007. 2004
    ....
  36. doi Combined trans-sphenoidal and simultaneous trans-ventricular-endoscopic decompression of a giant pituitary adenoma: case report
    Bal Krishna Ojha
    Department of Neurosurgery, CSM Earlier King George s Medical University, Lucknow 226003, India
    Acta Neurochir (Wien) 151:843-7; discussion 847. 2009
    ..This is the first report of the simultaneous combined use of trans-sphenoidal and trans-ventricular-endoscopic route for decompression of a giant pituitary adenoma...
  37. ncbi Intracranial pressure and cerebral hemodynamic in patients with cerebral tumors: a randomized prospective study of patients subjected to craniotomy in propofol-fentanyl, isoflurane-fentanyl, or sevoflurane-fentanyl anesthesia
    Kurt D Petersen
    Department of Anesthesia and Neurosurgery, Aarhus University Hospital, Denmark
    Anesthesiology 98:329-36. 2003
    A critical point during craniotomy is opening of dura, where a high intracranial pressure (ICP) results in swelling of cerebral tissue...
  38. ncbi Bone flap preservation after decompressive craniectomy--experience with 55 cases
    Prasad Krishnan
    Department of Neurosurgery, National Neurosciences Centre, Kolkata, 700 031, India
    Neurol India 54:291-2. 2006
    ....
  39. ncbi Craniotomy for resection of pediatric brain tumors in the United States, 1988 to 2000: effects of provider caseloads and progressive centralization and specialization of care
    Edward R Smith
    Massachusetts General Hospital, and Department of Surgery Neurosurgery, Harvard Medical School, Boston, Massachusetts 02114, USA
    Neurosurgery 54:553-63; discussion 563-5. 2004
    ..We used a national hospital discharge database to study the volume-outcome relationship for craniotomy performed for pediatric brain tumor resection, as well as trends toward centralization and specialization.
  40. ncbi Inhalational or intravenous anesthetics for craniotomies? Pro inhalational
    Kristin Engelhard
    Klinik fur Anasthesiologie, Johannes Gutenberg Universitat, Mainz, Germany
    Curr Opin Anaesthesiol 19:504-8. 2006
    ....
  41. ncbi Effect of prophylactic ondansetron on postoperative nausea and vomiting in patients on preoperative steroids undergoing craniotomy for supratentorial tumors
    Jyotsna Wig
    Department of Anaesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh, India
    J Neurosurg Anesthesiol 19:239-42. 2007
    ..sex who had received preoperative steroids (dexamethasone) for at least 24 hours and were scheduled to undergo craniotomy for supratentorial tumors were included...
  42. ncbi Prevention and control of postoperative nausea and vomiting in post-craniotomy patients
    L H J Eberhart
    Department of Anaesthesiology and Intensive Care, Philipps University Marburg, Baldingerstrasse, D 35033 Marburg, Germany
    Best Pract Res Clin Anaesthesiol 21:575-93. 2007
    ..However, emetic symptoms can also cause major medical complications, and post-craniotomy patients may be at an increased risk...
  43. ncbi Preservation of bone flap after craniotomy infection
    Pedro David Delgado-López
    Servicio de Neurocirugia, Hospital General Yague, Burgos
    Neurocirugia (Astur) 20:124-31. 2009
    The estimated incidence of craniotomy infection is 5%, ranging from 1-11% depending on the presence of certain risk factors, such as, prior radiation therapy, repeated surgery, CSF leak, duration of surgery over 4h, interventions ..
  44. ncbi Standard large trauma craniotomy for severe traumatic brain injury
    Li quan Lü
    Department of Neurosurgery, Changzheng Hospital, Second Military Medical University, Shanghai 200003, China
    Chin J Traumatol 6:302-4. 2003
    To study the effect of standard large trauma craniotomy (SLTC) on outcomes of patients with severe traumatic brain injury (TBI) (GCS<=8).
  45. doi Early recovery and better evacuation rate in neuroendoscopic surgery for spontaneous intracerebral hemorrhage using a multifunctional cannula: preliminary study in comparison with craniotomy
    Toru Nagasaka
    Department of Neurosurgery, Nagoya University Graduate School of Medicine, 65Tsurumai Cho, Nagoya, Aichi, Japan
    J Stroke Cerebrovasc Dis 20:208-13. 2011
    ..We sought to compare the clinical outcomes between neuroendoscopic surgery and craniotomy for spontaneous ICH...
  46. doi Age and salvageability: analysis of outcome of patients older than 65 years undergoing craniotomy for acute traumatic subdural hematoma
    Philipp Taussky
    Department of Neurosurgery, Kantonsspital Aarau, Aarau, Switzerland
    World Neurosurg 78:306-11. 2012
    ..Yet, the operative treatment of patients older than 65 years of age for aSDH remains controversial, and very limited data exists with regard to expected outcome in this elderly patient group...
  47. ncbi Bilateral orbital infarction syndrome after bifrontal craniotomy
    Philip Maier
    University Eye Hospital Freiburg, Killianstr 5, 79106 Freiburg, Germany
    Arch Ophthalmol 125:422-3. 2007
  48. doi Day surgery awake craniotomy for removing brain tumours: technical note describing a simple protocol
    G Carrabba
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, University of Toronto, 399 Bathurst Street, Toronto, Ontario, Canada
    Minim Invasive Neurosurg 51:208-10. 2008
    Day surgery awake craniotomy has been recently proposed for patients harbouring supratentorial brain tumours...
  49. ncbi Outpatient craniotomy for brain tumor: a pilot feasibility study in 46 patients
    M Bernstein
    Division of Neurosurgery, Toronto Western Hospital, University Health Network, ON, Canada
    Can J Neurol Sci 28:120-4. 2001
    BACKGROUND: Since 1991 the author has routinely performed awake craniotomy for intra-axial brain tumors with low complication rate and low resource utilization...
  50. doi Application accuracy of computed tomography-based, image-guided navigation of temporal bone
    Promod Pillai
    Department of Neurological Surgery, The Ohio State University Medical Center, Columbus, Ohio 43210, USA
    Neurosurgery 63:326-32; discussion 332-3. 2008
    ..We investigated the application accuracy of computed tomography-based, frameless, image-guided navigation to identify various bony structures in the temporal bone via a retrosigmoid approach...
  51. ncbi The effects of 10 degrees reverse trendelenburg position on ICP and CPP in prone positioned patients subjected to craniotomy for occipital or cerebellar tumours
    A Tankisi
    Department of Neuroanaesthesia, Aarhus Kommunehospital, Aarhus University Hospital, Denmark
    Acta Neurochir (Wien) 144:665-70. 2002
    Control of ICP-hypertension is of utmost importance during craniotomy. The effects of reverse Trendelenburg position (RTP) upon ICP and CPP have recently been studied in supine positioned patients.
  52. doi Is it time to replace the Wada test and put awake craniotomy to sleep?
    Andrew C Papanicolaou
    Department of Pediatrics, Division of Clinical Neurosciences, University of Tennessee Health Science Center, Memphis, Tennessee, U S A Neuroscience Institute, Le Bonheur Children s Hospital, Memphis, Tennessee, U S A
    Epilepsia 55:629-32. 2014
    ....
  53. ncbi Cerebellar hemorrhage after supratentorial craniotomy
    Gerhard Marquardt
    Neurosurgical Clinic, Johann Wolfgang Goethe University, Schleusenweg 2 16, 60528 Frankfurt am Main, Germany
    Surg Neurol 57:241-51; discussion 251-2. 2002
    Cerebellar hemorrhage following supratentorial craniotomy is a very seldom described but serious complication...
  54. ncbi Awake craniotomy for microsurgical obliteration of mycotic aneurysms: technical report of three cases
    Jürgen C Lüders
    Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio, USA
    Neurosurgery 56:E201; discussion E201. 2005
    ..Three cases of awake craniotomy for microsurgical clipping of mycotic aneurysms are presented...
  55. ncbi [Clinical observation of granisetron in preventing postoperative nausea and vomiting following supratentorial craniotomy]
    Yun jiao Wang
    Department of Anesthesiology, Xiangya Hospital, Central South University, Changsha 410008, China
    Hunan Yi Ke Da Xue Xue Bao 27:545-6. 2002
    To observe the prophylactic effect of granisetron on postoperative nausea and vomiting (PONV) after supratentorial craniotomy.
  56. ncbi Venous air embolism during awake craniotomy in a supine patient
    Mrinalini Balki
    Department of Anesthesia, The Toronto Western Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
    Can J Anaesth 50:835-8. 2003
    To report a non-fatal case of intraoperative venous air embolism (VAE) during an awake craniotomy. VAE presented with unusual clinical features.
  57. doi Is postoperative intensive care unit admission a prerequisite for elective craniotomy?
    John Q H Bui
    Department of Neurosurgery, Liverpool Hospital, University of New South Wales, Sydney, New South Wales, Australia
    J Neurosurg 115:1236-41. 2011
    ..to the intensive care unit (ICU) is often considered a necessity in the treatment of patients following elective craniotomy but may strain already limited resources and is of unproven benefit...
  58. doi Outcome of fully awake craniotomy for lesions near the eloquent cortex: analysis of a prospective surgical series of 79 supratentorial primary brain tumors with long follow-up
    Luiz Claudio Modesto Pereira
    Hospital de Base do Distrito Federal, Brasilia, Brazil
    Acta Neurochir (Wien) 151:1215-30. 2009
    Despite possible advantages, few surgical series report specifically on awake craniotomy for intrinsic brain tumors in eloquent brain areas.
  59. doi Surgical site infections following craniotomy focusing on possible post-operative acquisition of infection: prospective cohort study
    O Sneh-Arbib
    Unit of Infectious Diseases, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel
    Eur J Clin Microbiol Infect Dis 32:1511-6. 2013
    ..Included were adult patients undergoing clean or clean-contaminated craniotomy, including craniotomies with external CSF drainage or shunts...
  60. doi Awake craniotomy and electrophysiological mapping for eloquent area tumours
    Ari George Chacko
    Department of Neurological Sciences, Section of Neurosurgery, Christian Medical College, Vellore, Tamil Nadu, India
    Clin Neurol Neurosurg 115:329-34. 2013
    An awake craniotomy facilitates radical excision of eloquent area gliomas and ensures neural integrity during the excision. The study describes our experience with 67 consecutive awake craniotomies for the excision of such tumours.
  61. ncbi 'Scheduled' dosing of lornoxicam provides analgesia superior to that provided by 'on request' dosing following craniotomy
    Elena V Dolmatova
    Faculty of Basic Medicine, Moscow State University, Moscow, Russia
    Eur J Anaesthesiol 26:633-7. 2009
    The aim of this study was to compare the efficacy of 'scheduled' analgesia with analgesia 'on request in patients after craniotomy.
  62. ncbi The keyhole concept in aneurysm surgery--a comparative study: keyhole versus standard craniotomy
    J Paladino
    Department of Neurosurgery, School of Medicine, University of Zagreb, Croatia
    Minim Invasive Neurosurg 48:251-8. 2005
    The purpose of the study is to compare the results of minimally invasive keyhole craniotomy and standard larger craniotomies in the surgical treatment of patients with intracranial aneurysms.
  63. ncbi Salvage of infected craniotomy bone flaps with the wash-in, wash-out indwelling antibiotic irrigation system. Technical note and case series of 12 patients
    Kurtis I Auguste
    Department of Neurological Surgery, University of California, San Francisco School of Medicine, San Francisco, California 94143 0112, USA
    J Neurosurg 105:640-4. 2006
    When complicated by infection, craniotomy bone flaps are commonly removed, discarded, and delayed cranioplasty is performed...
  64. ncbi Sudden visual loss due to posterior ischemic optic neuropathy following craniotomy for a ruptured intracranial aneurysm
    Kishor A Choudhari
    Department of Neurosurgery, Royal Victoria Hospital, Regional Neurosciences Unit, Belfast BT12 6BA, United Kingdom
    Neurol India 55:163-5. 2007
    The authors report a rare case of acute ipsilateral blindness that occurred after a standard fronto-temporal craniotomy for aneurysm in supine position...
  65. doi Dexmedetomidine attenuates the hemodynamic and neuroendocrinal responses to skull-pin head-holder application during craniotomy
    Ahmet Senol Uyar
    Clinic of Anesthesiology and Reanimation, The Ministry of Health Ankara Research and Training Hospital, Ankara, Turkey
    J Neurosurg Anesthesiol 20:174-9. 2008
    ..heart rate, arterial blood pressure, and neuroendocrinal responses to skull-pin head-holder application during craniotomy. In a randomized, double-blinded, placebo-controlled study, 40 patients undergoing craniotomy with attachment of ..
  66. doi Effect of head positioning on outcome after burr hole craniostomy for chronic subdural haematoma
    Asim Ishfaq
    Department of Neurosurgery, Combined Military Hospital, Rawalpindi
    J Coll Physicians Surg Pak 19:492-5. 2009
    ..To determine the effect of position of the patient's head after burr hole craniostomy on the outcome of chronic subdural haematoma, in terms of haematoma efflux, hospital stay and recurrence rate...
  67. ncbi Effect of single-dose dexamethasone on blood glucose concentration in patients undergoing craniotomy
    Jeffrey J Pasternak
    Department of Anesthesiology, Mayo Clinic and College of Medicine, Rochester, Minnesota 55905, USA
    J Neurosurg Anesthesiol 16:122-5. 2004
    ..bolus of dexamethasone or a saline placebo were evaluated in nondiabetic patients undergoing elective craniotomy. Both arterial and venous blood glucose concentrations were obtained immediately before and after treatment and ..
  68. ncbi A randomized trial of very early decompressive craniectomy in children with traumatic brain injury and sustained intracranial hypertension
    A Taylor
    Intensive Care Department, Royal Children's Hospital, Melbourne, Victoria, Australia
    Childs Nerv Syst 17:154-62. 2001
    ..046; owing to multiple significance testing P <0.0221 is required for statistical significance). This pilot study suggests that very early decompressive craniectomy may be indicated in the treatment of traumatic brain injury...
  69. ncbi Extended pericranial flap and bone graft reconstruction in anterior skull base surgery
    Michael Rodrigues
    University of Maryland School of Medicine, University of Maryland Hospital, Baltimore, MD, USA
    Otolaryngol Head Neck Surg 131:69-76. 2004
    ..Study design Thirty-four patients underwent anterior craniofacial resection of anterior skull-based tumors of varying histology with reconstruction using an extended pericranial flap and split calvarial bone graft...
  70. ncbi Harvesting blood stem cells from cranial bone at craniotomy--a preliminary study
    Tomomi Iwashita
    Department of Neurosurgery, Aizawa Hospital, Shinshu University School of Medicine, Asahi, Matsumoto, Japan
    J Neurooncol 64:265-70. 2003
    ..In this study, we examined whether blood stem cells can be harvested from cranial bone at craniotomy. Bone marrow cells in cranial bone were counted in 181 craniotomy specimens after staining with hematoxylin and ..
  71. ncbi Routine use of postoperative ICU care for elective craniotomy: a cost-benefit analysis
    Curtis L Beauregard
    Department of Neurological Surgery, University of Florida, Gainesville, Florida 32610, USA
    Surg Neurol 60:483-9; dicussion 489. 2003
    Postoperative monitoring in an intensive care unit (ICU) setting following elective craniotomy is routine at many institutions, as it is believed that this reduces the incidence and potential seriousness of early postoperative ..
  72. ncbi Hemodynamic effects of decompressive craniotomy in MCA infarction: evaluation with perfusion CT
    Martin Bendszus
    Department of Neuroradiolgoy, University of Wurzburg, Josef Schneider Strasse 11, 97080 Wurzburg, Germany
    Eur Radiol 13:1895-8. 2003
    Decompressive craniotomy in hemispheric infarction has been reported to reduce mortality and improve outcome. Identifying tissue at risk and monitoring the benefit of craniotomy is hardly practical and has not been reported thus far...
  73. ncbi Clinical evaluation of the polypropylene-polyester knit used as a cranioplasty material
    S Andrzejak
    Department of Neurosurgery, Medical University of Lodz, Lodz, Poland
    Acta Neurochir (Wien) 147:973-6; discussion 976. 2005
    ..The paper presents clinical evaluation of the polypropylene-polyester knit used as a cranioplasty material...
  74. ncbi Dysfunction of the temporalis muscle after pterional craniotomy for intracranial aneurysms. Comparative, prospective and randomized study of one flap versus two flaps dieresis
    F C de Andrade Júnior
    Department of Neurological Surgery and Bucomaxillofacial Surgery Service, Pontifical Catholic University of São Paulo Medical Sciences School, Sorocaba, SP, Brazil
    Arq Neuropsiquiatr 56:200-5. 1998
    Patients with intracranial aneurysm(s) of the carotid artery territory, treated with pterional craniotomy, were prospectively and randomly addressed to one layer flap (n = 36) or myocutaneous (MC) versus two layers' dieresis (n = 32) or ..
  75. ncbi Rebleeding leads to poor outcome in ultra-early craniotomy for intracerebral hemorrhage
    L B Morgenstern
    Stroke Program, Department of Neurology, University of Texas Houston Medical School, 77030, USA
    Neurology 56:1294-9. 2001
    ..A modest benefit was previously demonstrated for hematoma evacuation within 12 hours of intracerebral hemorrhage onset. Perhaps surgery within 4 hours would further improve outcome...
  76. ncbi Postoperative epilepsy in patients undergoing craniotomy for glioblastoma multiforme
    A E Telfeian
    Dept of Neurosurgery, Hospital of the University of Pennsylvania, Philadelphia 19104, USA
    J Exp Clin Cancer Res 20:5-10. 2001
    ..The primary goal of this study was to determine who, of those undergoing craniotomy for GBM resection, is at risk for epilepsy...
  77. ncbi Remifentanil-propofol vs dexmedetomidine-propofol--anesthesia for supratentorial craniotomy
    Namigar Turgut
    Department of Anaesthesiology and Reanimation, S B Okmeydani Teaching and Research Hospital, Istanbul, Turkey
    Middle East J Anaesthesiol 20:63-70. 2009
    ..In a prospective randomized double-blind study 50 ASAI-III patients scheduled for supratentorial craniotomy, were allocated into two equal Groups. Group D patients (n = 25), received i.v...
  78. ncbi [Clinical observation on effect of huoxue jieyu decoction in treating depression after craniotomy: a report of 45 cases]
    Ning quan Zhou
    Department of Brain Surgery, Qiannan Prefacture People s Hospital, Guizhou
    Zhongguo Zhong Xi Yi Jie He Za Zhi 25:1020-2. 2005
    To observe the therapeutic effect of Huoxue Jieyu decoction (HJD) on patients with depression after craniotomy.
  79. ncbi Awake craniotomy under local anaesthesia and monitored conscious sedation for resection of brain tumours in eloquent cortex--outcomes in 20 patients
    David Low
    Department of Neurosurgery, National Neuroscience Institute, Tan Tock Seng Hospital, 11 Jalan Tan Tock Seng, Singapore 308433
    Ann Acad Med Singapore 36:326-31. 2007
    ..We review the safety and effectiveness of craniotomy under local anaesthesia and monitored conscious sedation for resection of mass lesions involving eloquent cortex.
  80. doi Surface landmarks for the junction between the transverse and sigmoid sinuses: application of the "strategic" burr hole for suboccipital craniotomy
    R Shane Tubbs
    Section of Pediatric Neurosurgery, Children s Hospital, Birmingham, Alabama, USA
    Neurosurgery 65:37-41; discussion 41. 2009
    ..We have studied external skull bony landmarks to facilitate the placement of the initial "strategic" burr hole just inferior and medial to the junction of transverse-sigmoid venous sinuses during standard retrosigmoid craniotomy.
  81. ncbi Combined transsphenoidal and pterional craniotomy approach to giant pituitary tumors
    Cargill H Alleyne
    Department of Neurosurgery, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Surg Neurol 57:380-90; discussion 390. 2002
    ..We describe a combined simultaneous approach to giant pituitary tumors and present a review of 10 patients undergoing this procedure with emphasis on patient selection, surgical technique, and results...
  82. doi Low-profile 1-piece bifrontal craniotomy for anterior skull base approach and reconstruction
    Fatma Ozlen
    Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
    J Craniofac Surg 21:233-8. 2010
    ..These pathologic lesions are treated by bifrontal craniotomy and anterior skull base approach, either primarily or combined with facial osteotomies...
  83. ncbi Comparison of the analgesic efficacy and respiratory effects of morphine, tramadol and codeine after craniotomy
    P S Sudheer
    University of Wales College of Medicine, Heath Park, Cardiff, UK
    Anaesthesia 62:555-60. 2007
    Pain after craniotomy remains a significant problem. The effect of morphine and tramadol patient-controlled analgesia (PCA) on arterial carbon dioxide tension is unknown in patients having such surgery...
  84. ncbi Craniotomy procedures are associated with less analgesic requirements than other surgical procedures
    P J Dunbar
    Department of Anesthesiology, Harborview Medical Center, University of Washington School of Medicine, Seattle 98104 2499, USA
    Anesth Analg 88:335-40. 1999
    ..Our results confirm that the average craniotomy patient has less postoperative pain than patients who undergo other surgical procedures, although patients who ..
  85. ncbi Post-craniotomy analgesia: current practices in British neurosurgical centres--a survey of post-craniotomy analgesic practices
    G C Roberts
    University Hospital of Wales, B4 Neurosurgery, Cardiff, Wales, UK
    Eur J Anaesthesiol 22:328-32. 2005
    An evaluation of post-craniotomy analgesia within the University Hospital of Wales Neurosurgical Unit, Cardiff, found that many patients were experiencing moderate to severe pain post-craniotomy...
  86. ncbi Craniotomy for treatment of unruptured aneurysms is not associated with long-term cognitive dysfunction
    Elizabeth Tuffiash
    Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Stroke 34:2195-9. 2003
    ..The goal of this study was to identify changes in cognitive function associated with surgical clipping of unruptured intracerebral aneurysms...
  87. ncbi [Craniotomy side for neck clipping of the anterior communicating aneurysm via the pterional approach]
    Shinichiro Okamoto
    Department of Neurosurgery, Osaka Red Cross Hospital, 5 53 Fudegasaki cho, Tennoji ku, Oasaka city, Osaka 543 8555, Japan
    No Shinkei Geka 30:285-91. 2002
    ..of the anterior communicating artery (Acom) aneurysm via the pterional approach was evaluated in terms of craniotomy side in 39 consecutive cases operated on by the senior surgeon from April 1991 through March 2000...
  88. doi Does hyperventilation improve operating condition during supratentorial craniotomy? A multicenter randomized crossover trial
    Adrian W Gelb
    Department of Anesthesia and Perioperative Care, University of California San Francisco, 521 Parnassus Ave, C 450, San Francisco, CA 94143 0648, USA
    Anesth Analg 106:585-94, table of contents. 2008
    ..crossover, randomized trial to evaluate surgeon-assessed brain bulk and measured intracranial pressure (ICP) in patients undergoing craniotomy for removal of supratentorial brain tumors during moderate hypocapnia or normocapnia.
  89. doi Passive real-time identification of speech and motor cortex during an awake craniotomy
    Jarod Roland
    Department of Neurological Surgery, Washington University School of Medicine, 660 South Euclid, St Louis, MO 63110, USA
    Epilepsy Behav 18:123-8. 2010
    ..reduce the amount of necessary stimulation, we used a passive mapping procedure in the setting of an awake craniotomy for tumor in two patients resection...
  90. doi The use of recombinant activated factor VIIa in coagulopathic traumatic brain injuries requiring emergent craniotomy: is it beneficial?
    Nathaniel McQuay
    Department of Surgery, University of Pennsylvania Health System, Trauma Critica Division, St Luke s Hosptial, USA
    J Neurosurg 111:666-71. 2009
    ..This study evaluates the outcomes of using rFVIIa as first-line therapy in patients with a severe TBI requiring emergent craniotomy that are coagulopathic.
  91. ncbi Awake craniotomy for aggressive resection of primary gliomas located in eloquent brain
    F B Meyer
    Department of Neurologic Surgery, Mayo Clinic, Rochester, Minn 55905, USA
    Mayo Clin Proc 76:677-87. 2001
    ....
  92. ncbi Dural arteriovenous fistula after craniotomy for pilocytic astrocytoma in a patient with protein S deficiency
    Reza Yassari
    Section of Neurosurgery, Department of Surgery and Pritzker School of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Surg Neurol 58:59-64; discussion 64. 2002
    ..We report an unusual case, which may provide insight into the etiology and pathogenesis of dural arteriovenous malformation...
  93. doi The use of continuous positive airway pressure during an awake craniotomy in a patient with obstructive sleep apnea
    Tessa Huncke
    Department of Anesthesiology, New York University Medical Center, Rusk Institute, New York, NY 10016, USA
    J Clin Anesth 20:297-9. 2008
    ..We describe the anesthetic management of a morbidly obese patient with obstructive sleep apnea who underwent awake craniotomy. The patient's personal continuous positive airway pressure (CPAP) machine was used to support ventilation ..
  94. ncbi Role of craniotomy in the management of pituitary adenomas and sellar/parasellar tumors
    Wael Musleh
    The University of Chicago, Division of Neurosurgery, Chicago, IL 60637, USA
    Expert Rev Anticancer Ther 6:S79-83. 2006
    ..Overall, craniotomies will continue to play a role in the management of patients with sellar/parasellar tumors, although patient selection and careful preoperative evaluation are key elements in choosing the most appropriate approach...
  95. ncbi Decompressive craniotomy: durotomy instead of duroplasty to reduce prolonged ICP elevation
    Ralf Burger
    Department of Neurosurgery, Georg August University, Robert Koch Str 40, 37075 Goettingen, Germany
    Acta Neurochir Suppl 102:93-7. 2008
    ..Several longitudinal durotomies avoid these limitations, but it remains a matter of discussion if durotomies reduce ICP sufficiently...
  96. ncbi Application of a hydrogel sealant improves watertight closures of duraplasty onlay grafts in a canine craniotomy model
    Mark C Preul
    Division of Neurological Surgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona 85013, USA
    J Neurosurg 107:642-50. 2007
    ..The authors evaluated whether a polyethylene glycol-based hydrogel sealant system improved dural closures with collagen-based duraplasty onlay grafts...
  97. ncbi Difficult airway management following supratentorial craniotomy: a useful maneuver with a new device
    Irene P Osborn
    Anesth Analg 105:552-3. 2007
  98. ncbi Orbitozygomatic craniotomy. Technical note
    J M Zabramski
    Division of Neurological Surgery, Barrow Neurological Institute, Mercy Healthcare Arizona, Phoenix, USA
    J Neurosurg 89:336-41. 1998
    ..At a follow-up evaluation after a period averaging 14 months, all patients were pleased with the cosmetic results of this approach...
  99. ncbi Early postoperative cognitive recovery after remifentanil-propofol or sufentanil-propofol anaesthesia for supratentorial craniotomy: a randomized trial
    F Bilotta
    Department of Anesthesiology, Intensive Care and Pain Medicine, University of Rome La Sapienza, Viale Somalia 81, 00199 Rome, Italy
    Eur J Anaesthesiol 24:122-7. 2007
    This study was designed to evaluate early postoperative cognitive recovery after total intravenous anaesthesia with remifentanil-propofol or sufentanil-propofol in patients undergoing craniotomy for supratentorial expanding lesions.
  100. ncbi Craniotomy for meningioma in the United States between 1988 and 2000: decreasing rate of mortality and the effect of provider caseload
    William T Curry
    Brain Tumor Center, Neurosurgical Service, Massachusetts General Hospital, Boston 02114, USA
    J Neurosurg 102:977-86. 2005
    ..The goal of this study was to determine the risk of adverse outcomes after contemporary surgical treatment of meningiomas in the US and trends in patient outcomes and patterns of care...
  101. doi Recombinant factor VIIa for the correction of coagulopathy before emergent craniotomy in blunt trauma patients
    Carlos V R Brown
    Department of Surgery, University of Texas Southwestern Medical School Austin, University Medical Center Brackenridge Trauma Services, Austin, Texas 78701, USA
    J Trauma 68:348-52. 2010
    ..We hypothesize that rFVIIa would provide an effective and cost efficient means of correcting coagulopathy in patients with traumatic brain injury undergoing emergent craniotomy.

Research Grants79

  1. HYPOTHERMIA DURING INTRACRANIAL ANEURYSM SURGERY
    Michael Todd; Fiscal Year: 2003
    ..of surgery performed to obliterate the source of bleeding; as many as 25 percent of patients who undergo craniotomy for aneurysm clipping will have a new neurologic deficit when examined 12-24hrs postoperatively...
  2. MAGNESIUM SULFATE FOR NEUROPROTECTION AFTER BRAIN TRAUMA
    Nancy Temkin; Fiscal Year: 2004
    ..Patients with moderate or severe head injury (post-resuscitation Glasgow Coma Scale 3-12 or having an early craniotomy) are randomized to receive moderate doses of magnesium sulfate or placebo...
  3. Decompressive craniotomy versus medical therapy for refractory intracranial hyper
    Raminder Nirula; Fiscal Year: 2010
    ..Decompressive craniotomy (DC) has been employed for refractory intracranial hypertension (ICH) for more than 50 years and has regained ..
  4. Cerebral Aneurysm Clipping Training Simulator using Virtual Reality and Haptics
    P Pat Banerjee; Fiscal Year: 2010
    ..This means that today, only 15% of cerebral aneurysms are treated by open craniotomy and aneurysm clipping as pioneered by M. G. Yasargil...
  5. Cerebral Aneurysm Clipping Training Simulator using Virtual Reality and Haptics
    P Pat Banerjee; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): IMMERSIVETOUCH(R) VIRTUAL REALITY-HAPTIC NEUROSURGERY SIMULATOR: CRANIOTOMY AND ANEURYSM CLIPPING Founded by principal investigator Dr. Pat Banerjee, ImmersiveTouch,(R) Inc...
  6. JAMES D KLEIN; Fiscal Year: 2014
    ..Wireless electrodes will allow complete closure of the craniotomy used for surgical placement and will avoid the use of the transcranial multiwire cables that connect the ..
  7. Auditory Thalamic Implant
    STEVEN WAN CHEUNG; Fiscal Year: 2012
    ..is implantation of intracranial devices to auditory structures accessible via infratentorial posterior fossa craniotomy under general anesthesia...
  8. Implementation and Effectiveness of a S. aureus Surgical Site Infection Preventio
    Loreen A Herwaldt; Fiscal Year: 2013
    ..aureus SSIs among patients undergoing CO, THA, TKA, spine operations (SO), or craniotomy/craniectomy (CRANI);2) Identify facilitators and barriers to bundle implementation at the hospital, surgical ..
  9. Capacity Building for Decompressive Craniotomy in Colombia
    Juan Carlos Puyana; Fiscal Year: 2013
    ..We will compare outcomes for sTBI patients treated before and after the introduction of the algorithm, which will provide preliminary data to support an RCT about DC in clinical settings without ICP monitors. ..
  10. Kris Moe; Fiscal Year: 2014
    ..in many instances, which has dramatically reduced the morbidity of gaining surgical access compared to an open craniotomy approach...
  11. Traumatic Brain Injury Clinical Trials Network
    Howard M Eisenberg; Fiscal Year: 2010
    ..The proposed study of decompression craniotomy could be initiated in a relatively short time once the funding period begins...
  12. ROBERT JAMES WEBSTER; Fiscal Year: 2016
    ..traditional approaches are highly invasive - they require either deconstruction of facial tissue and bone, or a craniotomy and associated trauma to the brain;and (3) there exists an underutilized, yet clinically proven alternative - ..
  13. EARLY HEMICRANIECTOMY TO MANAGE TRAUMATIC BRAIN INJURY
    William Coplin; Fiscal Year: 1999
    ..Group I will receive standardized hemicraniectomy; Group II will undergo traditional craniotomy with or without brain amputation, at the discretion of the attending neurosurgeon...
  14. JULIE GEORGIA PILITSIS; Fiscal Year: 2016
    ..A subset of patients are candidates for open surgery and/or SRS. Open surgery via craniotomy in appropriate patients allows for tissue diagnosis, rapid relief of symptoms, and local disease control...
  15. Wireless Multichannel Electrocorticogram Recording for Epilepsy Monitoring
    Stuart Cogan; Fiscal Year: 2009
    ..The wireless subdural arrays will allow complete closure of the craniotomy used for surgical placement and will avoid the use of the transcranial multiwire cables that connect the ..
  16. Regulation of Cranial Suture Development by TGF-Beta and Fibroblast Growth Factor
    Arun Gosain; Fiscal Year: 2007
    ..We will harvest tissue from both a fused suture and a patent suture from children undergoing craniotomy as part of the standard treatment for craniosynotosis...
  17. Revitalizing Allografts for Craniofacial Reconstruction
    Edward Schwarz; Fiscal Year: 2007
    ..In addition, 30% of all major neurosurgical procedures involve craniotomy: 5% are the result of head trauma and 25% are not related to trauma...
  18. RAPID ESTIMATION OF HUMAN BRAIN TUMOR GROWTH KINETICS
    Richard Davis; Fiscal Year: 1993
    ..of study, the BUdR labeling index (Ll) obtained from tumors that were exposed to a pulse of BUdR at the time of craniotomy have revealed that: 1) S phase fraction (or BUdR Ll) of individual brain tumors measured by BUdR labeling ..
  19. Patient and Health Care System Outcomes Following EEA
    Paula R Sherwood; Fiscal Year: 2013
    ..following EEA and to compare outcomes between persons undergoing EEA and those who have undergone standard craniotomy matched on key variables...
  20. Cognitive Function After Intracranial Aneurysm Surgery
    Satwant Samra; Fiscal Year: 2005
    ..partially blinded clinical study of the rate of recovery of cognitive function in patients who have undergone craniotomy for clipping of intracranial aneurysms...
  21. QUALITY OF LIFE--PARKINSON PATIENTS WITH NEURAL IMPLANTS
    Cynthia McRae; Fiscal Year: 1999
    ..Treatments include: 1) embryonic tissue implant and 2) sham surgery consisting of craniotomy alone. In the double-blind study, quality of life is assessed by a single global rating item...
  22. MAGNETIC RESONANCE SPECTROSCOPY--CLINICAL IMMUNOTHERAPY
    Brian Ross; Fiscal Year: 1991
    ..De-bulking of the tumor during craniotomy. 4) Implantation of fully activated lymphocytes, together with IL-2, into the tumor bed...
  23. FUNCATIONAL ORGANIZATION OF HUMAN PRIMARY MOTOR CORTEX
    Nancy Sicotte; Fiscal Year: 2001
    ..intrinsic signaling (0IS) and direct cortical stimulation (DCS) in a group of tumor patients undergoing awake craniotomy. The results of this work will lead to a better understanding of the, physiology of the human motor system as ..
  24. MODELING OF BRAIN DEFORMATION DURING SURGERY
    Keith Paulsen; Fiscal Year: 2002
    ..of these components has been demonstrated in a series of clinical cases analyzed retrospectively involving post-craniotomy brain sag which has been found to be one of the predominant modes of intraoperative brain deformation...
  25. NEURONAL CORRELATES OF HUMAN MEMORY
    George Ojemann; Fiscal Year: 2001
    ..Investigator's Abstract): Neural mechanisms of human memory are investigated utilizing a unique opportunity, craniotomy where the patient is awake under local anesthesia for a portion of the operation...
  26. CELLULAR MECHANISMS OF CRANIAL NONUNION FORMATION
    John Schmitz; Fiscal Year: 1993
    ..A craniofacial nonunion model will be developed in rats using 8 mm craniotomy defects...
  27. Estrogen and the Aging Blood Brain Barrier
    OAK CHI; Fiscal Year: 2002
    ..The information obtained from our study will be crucially important for the clinical application of estrogen therapy for stroke as well as understanding the pathophysiology of age related cerebrovascular changes. ..
  28. NABTC Member Intitution Grant (UCSF Project Leader)
    Susan Chang; Fiscal Year: 2008
    ..The overall goal of this program is to more effectively treat patients with primary brain tumors, especially malignant glioma, with the purpose of increasing the duration and quality of survival. ..
  29. Novel MRI Contrast Agent for Monitoring Thermal Ablation
    Nathan Mcdannold; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  30. INVESTIGATION OF DOSE/EFFICACY PROPERTIES OF INTRAVENTR*
    Daniel Hanley; Fiscal Year: 2008
    ..Abstract Not Provided ..
  31. Discovery of novel fluorescent reporter genes
    Ming Zhao; Fiscal Year: 2004
    ..Reporters with spectral properties that can be used for whole-body imaging of tumors in the lung and their metastases will be candidates for further development for numerous applications of multi-color imaging. ..
  32. EGFR activity in T cell-influenced glioma invasiveness & chemosensitivity
    Christopher Wheeler; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  33. VESTIBULAR EFFECTS OF INTRATYMPANIC GENTAMICIN
    John Carey; Fiscal Year: 2005
    ..Johns Hopkins is uniquely suited to this training because it has a core group devoted to vestibular research, and the mentor's laboratory has successfully used all of the techniques required. ..
  34. In Vivo Imaging of Post-Traumatic Cerebral Amyloid Deposition
    Marvin Bergsneider; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  35. Intracerebral Infusion of Radiolabeled Specific Antibody
    John Sampson; Fiscal Year: 2006
    ..abstract_text> ..
  36. Dendritic Cell Immunotherapy of Malignant Gliomas
    John Sampson; Fiscal Year: 2006
    ..abstract_text> ..
  37. Evalution of Vestibular Function in Meniere's Disease
    John Carey; Fiscal Year: 2009
    ..Comparisons of angular and translational VOR deficits after intratympanic gentamicin should demonstrate whether or not the utricle is less susceptible than the semicircular canals to intratympanic gentamicin. ..
  38. MENTORED PATIENT ORIENTED RESEARCH CAREER DEVELOPMENT AW
    John Sampson; Fiscal Year: 2004
    ....
  39. Trauma Center Brief Alcohol Treatments and Cost Effectivenes
    Thomas J Esposito; Fiscal Year: 2010
    ..New knowledge of the effectiveness, benefits and costs of these two Bl approaches would allow surgeons and trauma centers to make informed choices about alcohol interventions in trauma settings. ..
  40. ECM in Structure & Function of the Craniofacial Complex
    Paul Krebsbach; Fiscal Year: 2005
    ..The program will focus on the following areas: The Role of the Extracellular Matrix in: A) Suture formation B) Bone C) Teeth: Enamel D) Dentin and Cementum E) Temporomandibular Joint. ..
  41. A HEMODYNAMIC MODEL OF INTRACRANIAL PRESSURE DYNAMICS
    Marvin Bergsneider; Fiscal Year: 2002
    ..An improved understanding of these disorders will offer new and better treatment modalities for millions of affected patients. ..
  42. Optimization of TMS for Depression
    Mark George; Fiscal Year: 2009
    ..This clinical site grant (CSG) proposal is one of four scientifically identical proposals resubmitted under a CSMD mechanism.] ..
  43. Antisense imaging of brain gene expression in vivo
    William Pardridge; Fiscal Year: 2005
    ..This technology could be extended to humans and to other organs. At present, there is no parallel technology that enables the non-invasive in vivo imaging of "any gene in any person," which is the goal of this work. ..
  44. Effects of Amino Acid Therapy on Hot Flashes in Postmenopausal Women
    Thomas Guttuso; Fiscal Year: 2007
    ..The applicant will also attend two didactic training seminars in complementary & alternative medicine at The Osher Institute at Harvard Medical School and at the Duke Center for Integrative Medicine. ..
  45. GENE REGULATION AND FUNCTION OF AMELOBLASTIN
    Paul Krebsbach; Fiscal Year: 2003
    ....
  46. Cortical Basis of Perceptual Grouping
    CHARLES GRAY; Fiscal Year: 2005
    ..Together, these experiments will enable us to investigate the neuronal correlate of contour integration in striate cortex, and advance our understanding of scene segmentation processes in general. ..
  47. Polysomal RNA Antitumor Immunity
    John Chi; Fiscal Year: 2005
    ..Results from these experiments will help characterize the potential use of dendritic cells transfected with polysomal RNA in creating antigen specific tumor vaccines for brain tumors. ..
  48. Corticocortical interactions in visual working memory
    CHARLES GRAY; Fiscal Year: 2005
    ..New analytical methods will be incorporated to evaluate and interpret the resulting data. And, completion of this initial phase of the research plan will form the basis for future applications. ..
  49. NITROXIDERGIC CEREBROVASCULAR TONE DURING ANESTHESIA
    Shailendra Joshi; Fiscal Year: 2005
    ..abstract_text> ..
  50. Minimally Invasive Approaches for Craniofacial Surgery
    Maria Troulis; Fiscal Year: 2005
    ..abstract_text> ..
  51. Neurotrophin Blood/Brain Barrier Delivery in Ischemia
    William Pardridge; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  52. BONE MARROW STROMAL CELLS FOR SKELETAL REGENERATION
    Paul Krebsbach; Fiscal Year: 2005
    ..The information gained from this study will provide an essential prerequisite for the development of regenerative approaches that utilize bone marrow stromal cells for gene-and cell-based therapies. ..
  53. Optimization of TMS for Depression - Coordinating Center
    Mark George; Fiscal Year: 2009
    ..This coordinating Center Grant (CCG) application is submitted under a CSMD mechanism, linked to 4 clinical site grants (CSG). ..
  54. Genetic Analysis of Age Related Hearing Impairment
    Rick A Friedman; Fiscal Year: 2010
    ..This improved knowledge base can be anticipated to constitute fertile ground for developing new evidence-based preventive and therapeutic approaches to treating ARHI. ..
  55. MOOD EFFECTS OF DEEP BRAIN STIMULATION IN PARKINSONS
    Mark George; Fiscal Year: 2002
    ..Thus, we plan to use interleaved fMRI and DBS to directly examine the effects of DBS on hypothesized brain circuits and to correlate this with immediate and longer-term (4 week) behavioral outcomes (mood and cognition). ..
  56. GENE REGULATION AND FUNCTION OF AMELOBLASTIN
    Paul Krebsbach; Fiscal Year: 2002
    ....
  57. Inhibitors of 5alpha-reductase for acne therapy
    Lingna Li; Fiscal Year: 2002
    ..PROPOSED COMMERCIAL APPLICATIONS: Liposomal 4-MA will be developed as a topical selectively targeted therapeutic for acne for which they should be a very market. ..
  58. Study of a genetic network involved in ear development
    Rick Friedman; Fiscal Year: 2005
    ..These and future experiments represent the natural progression from my Mentored Clinical Scientist Development Award (K08). ..
  59. NEURONAL PROCESSING OF NATURAL IMAGES
    CHARLES GRAY; Fiscal Year: 2001
    ..These data will allow us to address the questions posed above, and thus improve our understanding of the behavior of primary visual cortex under natural conditions. ..
  60. REGULATION OF BBB GLUT1 GLUCOSE TRANSPORTER
    William Pardridge; Fiscal Year: 2002
    ..These studies will provide insight into molecular mechanisms of regulation of a step crucial to the maintenance of cerebral intermediary metabolism, i.e., the continuous transport of glucose across the blood-brain barrier in vivo. ..
  61. CEREBELLUM--ROLE IN THE CHEMICAL CONTROL OF BREATHING
    Fadi Xu; Fiscal Year: 2003
    ..Perhaps, more exciting is the emerging concept that the cerebellum may be far more involved in the planning and executing of motor responses, including respiration, than we have heretofore imagined. ..
  62. AIDS Neurotherapeutics and BBB Drug Efflux
    William Pardridge; Fiscal Year: 2007
    ..This work provides the basis for future drug discovery of AET blockers, which can be used as co-drugs to increase CNS penetration of HAART drugs. ..
  63. Chromatin-based cellular memory in neural stem cells
    Daniel Lim; Fiscal Year: 2009
    ..Furthermore, our studies may lead to discoveries of how derangements in chromatin remodeling can lead to the development of brain tumors. ..
  64. Regulation of VEGF/HIF-1 by AKT: Implications for Radiotherapy
    Amit Maity; Fiscal Year: 2010
    ..Increased oxygenation should make tumors more sensitive to radiation;therefore, our studies may be important in helping to optimize the combination of EGFR inhibitors with radiation. ..
  65. TOPOTECAN BY INTRACEREBRAL CLYSIS FOR BRAIN TUMORS
    Jeffrey Bruce; Fiscal Year: 2006
    ..abstract_text> ..
  66. LENTIVIRAL DELIVERY OF GDNF AND BCL-2 IN PD MODEL
    Marina Emborg; Fiscal Year: 2003
    ..These studies will serve as the preclinical foundation to determine whether this in vivo method to deliver these potent trophic factor and antiapoptotic genes will be suitable for testing in patients with PD. ..
  67. Adenoviral GFP targeting of metastatic human tumors using multiple delivery route
    Hiroyuki Kishimoto; Fiscal Year: 2008
    ..Having obtained these results, we can move forward in the Phase II grant application with experiments to bring OBP-401 to the clinic for use in cancer surgery in human patients. [unreadable] [unreadable] [unreadable]..
  68. Differential Gene Expression in the Cochlear Nucleus
    David Friedland; Fiscal Year: 2008
    ..These data will also provide a powerful template upon which to test and design novel treatments for improving hearing, discrimination and tinnitus in a significant portion of the population. ..
  69. Non-Viral Gene Targeting to the Brain
    William Pardridge; Fiscal Year: 2008
    ..abstract_text> ..
  70. Age-Dependent Response of Hippocampal Neurons to Stress
    Gregory Brewer; Fiscal Year: 2006
    ..abstract_text> ..
  71. Participating Member Institution in NABTC
    Lisa DeAngelis; Fiscal Year: 2008
    ..abstract_text> ..
  72. Orthotopic models of tumor angiogenesis and blood flow
    Meng Yang; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  73. Targeted tumoricidal bacteria
    Ming Zhao; Fiscal Year: 2007
    ..Future human trials of the tumor-killing bacteria can be held after the Phase I and Phase II grant periods are completed. [unreadable] [unreadable] [unreadable]..
  74. Ninth International Conference on the Chemistry and Biology of Mineralized Tissue
    Paul Krebsbach; Fiscal Year: 2007
    ..The ensuing "cross pollenization" of perspective and expertise is the ideal venue to enhance the process of discovery in this important field. [unreadable] [unreadable] [unreadable]..
  75. Central Mechanisms of Respiratory Arrest
    Fadi Xu; Fiscal Year: 2007
    ..unreadable] [unreadable]..