neurosurgical procedures

Summary

Summary: Surgery performed on the nervous system or its parts.

Top Publications

  1. ncbi Intraoperative MRI guidance and extent of resection in glioma surgery: a randomised, controlled trial
    Christian Senft
    Department of Neurosurgery, Goethe University, Frankfurt, Germany
    Lancet Oncol 12:997-1003. 2011
  2. ncbi A new minimally invasive tubular brain retractor system for surgery of deep intracerebral hematoma
    Yad R Yadav
    Department of Neurosurgery, NSCB Medical College and Apex Hospital, Jabalpur, MP, India
    Neurol India 59:74-7. 2011
  3. ncbi Endoscopic endonasal transsphenoidal surgery for growth hormone-secreting pituitary adenomas
    Christoph P Hofstetter
    Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10021, USA
    Neurosurg Focus 29:E6. 2010
  4. ncbi Lateral supraorbital approach vs pterional approach: an anatomic qualitative and quantitative evaluation
    Asem Salma
    Department of Neurological Surgery, Ohio State University Medical Center, 1645 Neil Avenue, Columbus, OH 43210, USA
    Neurosurgery 68:364-72; discussion 371-2. 2011
  5. ncbi Awake surgery for WHO Grade II gliomas within "noneloquent" areas in the left dominant hemisphere: toward a "supratotal" resection. Clinical article
    Yordanka N Yordanova
    Department of Neurosurgery, Hopital Gui de Chauliac, CHU Montpellier, France
    J Neurosurg 115:232-9. 2011
  6. ncbi Intra-operative 3D ultrasound in neurosurgery
    G Unsgaard
    Department of Neurosurgery, St Olav University Hospital, Trondheim, Norway
    Acta Neurochir (Wien) 148:235-53; discussion 253. 2006
  7. ncbi Utilization of magnetoencephalography results to obtain favourable outcomes in epilepsy surgery
    Michael J M Fischer
    Department of Neurology, Epilepsy Neurocentre, University of Erlangen Nuremberg, Erlangen, Germany
    Brain 128:153-7. 2005
  8. ncbi Application accuracy in frameless image-guided neurosurgery: a comparison study of three patient-to-image registration methods
    Peter A Woerdeman
    Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    J Neurosurg 106:1012-6. 2007
  9. ncbi Two applications of end-to-side nerve neurorrhaphy in severe upper-extremity nerve injuries
    Fuat Yuksel
    Department of Plastic and Reconstructive Surgery, Gulhane Military Medical Academy, Haydarpasa Hospital, Uskudar, Istanbul, Turkey 34668
    Microsurgery 24:363-8. 2004
  10. ncbi Management of brain metastases: the indispensable role of surgery
    George Al-Shamy
    Department of Neurosurgery, Baylor College of Medicine and The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Neurooncol 92:275-82. 2009

Detail Information

Publications278 found, 100 shown here

  1. ncbi Intraoperative MRI guidance and extent of resection in glioma surgery: a randomised, controlled trial
    Christian Senft
    Department of Neurosurgery, Goethe University, Frankfurt, Germany
    Lancet Oncol 12:997-1003. 2011
    ..Intraoperative MRI is increasingly used in neurosurgery, although there is little evidence for its use. We aimed to assess efficacy of intraoperative MRI guidance on extent of resection in patients with glioma...
  2. ncbi A new minimally invasive tubular brain retractor system for surgery of deep intracerebral hematoma
    Yad R Yadav
    Department of Neurosurgery, NSCB Medical College and Apex Hospital, Jabalpur, MP, India
    Neurol India 59:74-7. 2011
    ..Near-total removals of intracerebral hematomas, 37 hypertensive and 3 traumatic, was done using this retractor without any complication...
  3. ncbi Endoscopic endonasal transsphenoidal surgery for growth hormone-secreting pituitary adenomas
    Christoph P Hofstetter
    Department of Neurological Surgery, Weill Cornell Medical College, New York Presbyterian Hospital, New York, New York 10021, USA
    Neurosurg Focus 29:E6. 2010
    ..The aim of this study was to determine the preoperative predictors of the extent of resection and endocrinological remission following endonasal endoscopic removal of growth hormone (GH)-secreting pituitary adenomas...
  4. ncbi Lateral supraorbital approach vs pterional approach: an anatomic qualitative and quantitative evaluation
    Asem Salma
    Department of Neurological Surgery, Ohio State University Medical Center, 1645 Neil Avenue, Columbus, OH 43210, USA
    Neurosurgery 68:364-72; discussion 371-2. 2011
    ..Several minimally invasive modifications of the standard pterional approach have been proposed recently. The lateral supraorbital approach is one of these modifications...
  5. ncbi Awake surgery for WHO Grade II gliomas within "noneloquent" areas in the left dominant hemisphere: toward a "supratotal" resection. Clinical article
    Yordanka N Yordanova
    Department of Neurosurgery, Hopital Gui de Chauliac, CHU Montpellier, France
    J Neurosurg 115:232-9. 2011
    ..Their aim was to apply this reliable surgical technique to LGGs located not within eloquent areas but distant from eloquent areas, to take a margin around the LGG visible on MR imaging while preserving brain function...
  6. ncbi Intra-operative 3D ultrasound in neurosurgery
    G Unsgaard
    Department of Neurosurgery, St Olav University Hospital, Trondheim, Norway
    Acta Neurochir (Wien) 148:235-53; discussion 253. 2006
    ....
  7. ncbi Utilization of magnetoencephalography results to obtain favourable outcomes in epilepsy surgery
    Michael J M Fischer
    Department of Neurology, Epilepsy Neurocentre, University of Erlangen Nuremberg, Erlangen, Germany
    Brain 128:153-7. 2005
    ..This study shows that MEG source localization can help to delineate epileptic activity and, along with other techniques, should be taken into account for epilepsy surgery...
  8. ncbi Application accuracy in frameless image-guided neurosurgery: a comparison study of three patient-to-image registration methods
    Peter A Woerdeman
    Department of Neurology and Neurosurgery, Rudolf Magnus Institute of Neuroscience, University Medical Center Utrecht, The Netherlands
    J Neurosurg 106:1012-6. 2007
    ..The mathematical relationship between the image volume and the surgical working space is calculated using a rigid body transformation algorithm, based on point-pair matching or surface matching...
  9. ncbi Two applications of end-to-side nerve neurorrhaphy in severe upper-extremity nerve injuries
    Fuat Yuksel
    Department of Plastic and Reconstructive Surgery, Gulhane Military Medical Academy, Haydarpasa Hospital, Uskudar, Istanbul, Turkey 34668
    Microsurgery 24:363-8. 2004
    ..Based on these results and our review of the current literature, we consider alternative nerve repair techniques to be reasonable, prudent, and scientific choices for the treatment of some challenging nerve injury cases...
  10. ncbi Management of brain metastases: the indispensable role of surgery
    George Al-Shamy
    Department of Neurosurgery, Baylor College of Medicine and The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030, USA
    J Neurooncol 92:275-82. 2009
    ..Achieving the best outcome in treatment of brain metastasis requires the judicious and complementary use of surgical resection along with modalities such as whole-brain radiation therapy and stereotactic radiosurgery...
  11. ncbi Predictors of epilepsy surgery outcome: a meta-analysis
    C Tonini
    Laboratory of Neurological Disorders, Institute for Pharmacological Research Mario Negri, Via Eritrea, 62, 20157 Milan, Italy
    Epilepsy Res 62:75-87. 2004
    ....
  12. ncbi Prognostic factors for outcome in patients with aneurysmal subarachnoid hemorrhage
    Axel J Rosengart
    Neurocritical Care and Acute Stroke Program, Department of Neurology, University of Chicago Medical Center, Chicago, IL, USA
    Stroke 38:2315-21. 2007
    ..The purpose of this study was to describe prognostic factors for outcome in a large series of patients undergoing neurosurgical clipping of aneurysms after subarachnoid hemorrhage (SAH)...
  13. ncbi Did survival improve after the implementation of intraoperative neuronavigation and 3D ultrasound in glioblastoma surgery? A retrospective analysis of 192 primary operations
    C A Sæther
    Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway
    J Neurol Surg A Cent Eur Neurosurg 73:73-8. 2012
    ..The aim of the present study was to examine if the introduction of 3D ultrasound and neuronavigation (i. e., the SonoWand® system) may have had an impact on overall survival...
  14. ncbi Increasing treatment of ruptured cerebral aneurysms at high-volume centers in the United States
    Caleb B Leake
    Mayo Medical School, Rochester, Minnesota 55905, USA
    J Neurosurg 115:1179-83. 2011
    ..The authors evaluated the US National Inpatient Sample for the years 2001 to 2008 for trends in patient admissions for the treatment of ruptured aneurysms at high- and low-volume centers...
  15. ncbi Predictors of clinical and angiographic outcome after surgical or endovascular therapy of very large and giant intracranial aneurysms
    Tim E Darsaut
    Department of Neurosurgery, Stanford Stroke Center and Stanford Institute for Neuro Innovation and Translational Neurosciences, Stanford University School of Medicine, Stanford, California 94305 5325, USA
    Neurosurgery 68:903-15; discussion 915. 2011
    ..Risk factors for poor outcome in the treatment of very large (≥20-24 mm) and giant (≥25 mm) intracranial aneurysms remain incompletely defined...
  16. ncbi Neuromonitoring after major neurosurgical procedures
    M Messerer
    Division of Neurosurgery, Department of Clinical Neurosciences, Centre Hospitalier Universitaire Vaudois, Lausanne University Hospital and Faculty of Biology and Medicine, Lausanne, Switzerland
    Minerva Anestesiol 78:810-22. 2012
    Postoperative care of major neurosurgical procedures is aimed at the prevention, detection and treatment of secondary brain injury. This consists of a series of pathological events (i.e...
  17. ncbi Current management of middle cerebral artery aneurysms: surgical results with a "clip first" policy
    Ana Rodríguez-Hernández
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, California 94143, USA
    Neurosurgery 72:415-27. 2013
    ..Surgical results with middle cerebral artery (MCA) aneurysms have been excellent, raising debate about the respective roles of surgical and endovascular therapy...
  18. ncbi How to choose clipping versus coiling in treating intracranial aneurysms
    T E Darsaut
    Departement de Radiologie, Centre Hospitalier de l Universite de Montreal, Hopital Notre Dame, 1560 Sherbrooke Est, Pavillon Simard, suite Z12909, Montreal, Quebec, H2L 4M1 Canada
    Neurochirurgie 58:61-75. 2012
    ..The rationale underlying the choice of treatment modality is usually unclear, as there is little good quality evidence available...
  19. ncbi Long-term seizure outcomes following epilepsy surgery: a systematic review and meta-analysis
    Jose F Tellez-Zenteno
    Department of Clinical Neurological Sciences, London Health Sciences Centre, London, Ontario, Canada
    Brain 128:1188-98. 2005
    ..On the other hand, long-term seizure freedom was consistently lower after extratemporal surgery and palliative procedures...
  20. ncbi Extent of surgical resection is independently associated with survival in patients with hemispheric infiltrating low-grade gliomas
    Matthew J McGirt
    Department of Neurosurgery, The Johns Hopkins School of Medicine, and Neuro Oncology Surgical Outcomes Research Laboratory, Baltimore, Maryland 21231, USA
    Neurosurgery 63:700-7; author reply 707-8. 2008
    ..It remains unknown whether the extent of surgical resection affects survival or disease progression in patients with supratentorial low-grade gliomas...
  21. ncbi Ultrasound-guided operations in unselected high-grade gliomas--overall results, impact of image quality and patient selection
    Ole Solheim
    Department of Neuroscience, Norwegian University of Science and Technology, 7005, Trondheim, Norway
    Acta Neurochir (Wien) 152:1873-86. 2010
    ..Delineation of seemingly similar brain tumours vary in different ultrasound-guided operations, perhaps limiting usefulness in certain patients...
  22. ncbi Application of intraoperative high-field magnetic resonance imaging in pediatric neurosurgery
    Ron Levy
    Division of Neurosurgery, Department of Clinical Neuroscience, Faculty of Medicine, University of Calgary, Foothills Medical Centre, Calgary, Alberta, Canada
    J Neurosurg Pediatr 4:467-74. 2009
    ..5-T iMR imaging unit with integrated neuronavigation with the goal of identifying procedures and/or pathologies in which the application of this technology changed the course of surgery or modified the operative strategy...
  23. ncbi Evidence of improved surgical outcome following endoscopy for nonfunctioning pituitary adenoma removal
    Mahmoud Messerer
    Département de Neurochirurgie A, Hopital Neurologique Pierre Wertheimer, Groupement Hospitalier Est, Hospices Civils de Lyon, Bron, France
    Neurosurg Focus 30:E11. 2011
    ..The authors' aim in this study was to compare the clinical results and morbidity between microscopic and endoscopic techniques in 164 patients with NFPAs...
  24. ncbi Length of stay and total hospital charges of clipping versus coiling for ruptured and unruptured adult cerebral aneurysms in the Nationwide Inpatient Sample database 2002 to 2006
    Brian L Hoh
    Department of Neurological Surgery, University of Florida, Gainesville, Fla 32610, USA
    Stroke 41:337-42. 2010
    ..We now report an analysis of the same comparison at a national level conducted using the Nationwide Inpatient Sample database...
  25. ncbi Critical risk factors for intellectual impairment in children with posterior fossa tumors: the role of cerebellar damage
    Jacques Grill
    Department of Paediatric and Adolescent Oncology, Gustave Roussy Institute, Villejuif, France
    J Neurosurg 101:152-8. 2004
    ..The authors studied the effects in 76 children treated for a malignant posterior fossa tumor in a cross-sectional study...
  26. ncbi Transsphenoidal approaches to the pituitary: a progression in experience in a single centre
    Bulent Duz
    Department of Neurosurgery, School of Medicine, GATA, Gulhane Military Medical Academy GATA TR 06018 Etlik, Ankara, Turkey
    Acta Neurochir (Wien) 150:1133-8; discussion 1138-9. 2008
    ..Evolving of a single centre by means of different transsphenoidal approaches during the survey of methodological advances in pituitary surgery is presented...
  27. ncbi Virtual temporal bone: an interactive 3-dimensional learning aid for cranial base surgery
    Ralf A Kockro
    Department of Neurosurgery, University of Mainz, Mainz, Germany
    Neurosurgery 64:216-29; discussion 229-30. 2009
    ..We have developed an interactive virtual model of the temporal bone for the training and teaching of cranial base surgery...
  28. ncbi Comparison of navigated 3D ultrasound findings with histopathology in subsequent phases of glioblastoma resection
    Ola Morten Rygh
    Department of Radiology, St Olav University Hospital, Trondheim, Norway
    Acta Neurochir (Wien) 150:1033-41; discussion 1042. 2008
    ..The purpose of the study was to compare the ability of navigated 3D ultrasound to distinguish tumour and normal brain tissue at the tumour border zone in subsequent phases of resection...
  29. ncbi Four subtypes of petroclival meningiomas: differences in symptoms and operative findings using the anterior transpetrosal approach
    S Ichimura
    Department of Neurosurgery, Keio University School of Medicine, Tokyo, Japan
    Acta Neurochir (Wien) 150:637-45. 2008
    ..This report subclassifies petroclival meningiomas based on their origin determined by using radiological and intra-operative findings...
  30. pmc Does an interspinous device (Coflex) improve the outcome of decompressive surgery in lumbar spinal stenosis? One-year follow up of a prospective case control study of 60 patients
    Alexander Richter
    Spine Center Hamburg, Asklepios Klinik St Georg, Hamburg, Germany
    Eur Spine J 19:283-9. 2010
    ..To the best of our knowledge this is the first prospective controlled study which compares surgical decompression of lumbar spinal stenosis with additional implanting of an interspinous Coflex device in the treatment of symptomatic LSS...
  31. ncbi Frameless neuronavigation in intracranial endoscopic neurosurgery
    H W Schroeder
    Department of Neurosurgery, Ernst Moritz Arndt University, Greifswald, Germany
    J Neurosurg 94:72-9. 2001
    ..The purpose of this study was to determine in which intracranial neuroendoscopic procedures frameless neuronavigation is necessary and really beneficial compared with a free-hand endoscopic approach...
  32. ncbi Risk factors for fever in the neurologic intensive care unit
    Christopher Commichau
    Division of Critical Care Neurology, Department of Neurology, Columbia University College of Physicians and Surgeons, New York, NY, USA
    Neurology 60:837-41. 2003
    ..To identify risk factors for fever among patients treated in a neurologic intensive care unit (NICU)...
  33. ncbi Hemodilution and fluid management in neurosurgery
    Ramachandra P Tummala
    Department of Neurological Surgery, University of Miami School of Medicine, Florida, USA
    Clin Neurosurg 53:238-51. 2006
  34. ncbi Predicting long-term seizure outcome after resective epilepsy surgery: the multicenter study
    S S Spencer
    Department of Neurology, Yale University School of Medicine, New Haven, CT 06520 8018, USA
    Neurology 65:912-8. 2005
    ..In a seven-center prospective observational study of resective epilepsy surgery, the authors examined probability and predictors of entering 2-year remission and the risk of subsequent relapse...
  35. ncbi Surgical interventions for lumbar disc prolapse: updated Cochrane Review
    J N Alastair Gibson
    Spinal Unit, Royal Infirmary of Edinburgh and the University of Edinburgh, Edinburgh, Scotland
    Spine (Phila Pa 1976) 32:1735-47. 2007
    ..An updated Cochrane Review...
  36. ncbi Endoscopic transsphenoidal surgery
    H D Jho
    Center for Minimally Invasive Innovative Microneurosurgery, Department of Neurological Surgery, University of Pittsburgh School of Medicine, PA, USA
    J Neurooncol 54:187-95. 2001
    ..This endonasal transsphenoidal endoscopy eliminates a sublabial or transfixional incision, the use of a transsphenoidal retractor and any nasal packing...
  37. ncbi The endoscopic versus the traditional approach in pituitary surgery
    Giorgio Frank
    Center of Surgery for Pituitary Tumors, Department of Neuroscience, Bellaria Hospital, Bologna, Italy
    Neuroendocrinology 83:240-8. 2006
    ....
  38. ncbi Lateral supraorbital approach as an alternative to the classical pterional approach
    J Hernesniemi
    Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland
    Acta Neurochir Suppl 94:17-21. 2005
    ..The senior author (JH) established a lateral supraorbital approach as an alternative to the pterional approach after continuous trial and error. We describe the techniques of this approach based on clinical experiences...
  39. ncbi Intraoperative subcortical stimulation mapping for hemispherical perirolandic gliomas located within or adjacent to the descending motor pathways: evaluation of morbidity and assessment of functional outcome in 294 patients
    G Evren Keles
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 100:369-75. 2004
    ..The purpose of this retrospective analysis was to assess the morbidity and functional outcome associated with this method, thus allowing the surgeon to predict the likelihood of causing a temporary or permanent motor deficit...
  40. ncbi Insular glioma resection: assessment of patient morbidity, survival, and tumor progression
    Nader Sanai
    Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
    J Neurosurg 112:1-9. 2010
    ....
  41. ncbi 3-Tesla intraoperative MR imaging for neurosurgery
    Walter A Hall
    Department of Neurosurgery, University of Minnesota Medical School and Hennepin County Medical Center, Menniapolis, MN 55455, USA
    J Neurooncol 77:297-303. 2006
    ..There were no adverse events associated with any procedure. MR-guided neurosurgery can be safely and effectively performed at 3-T. The surgical environment at 3-T is comparable to that present at 1.5-T...
  42. ncbi Nerve surgery: a review and insights about its future
    Wale A R Sulaiman
    Section of Neurosurgery, University of Manitoba, Winnipeg, Canada
    Clin Neurosurg 53:38-47. 2006
  43. ncbi Intraoperative MR-guided neurosurgery
    Walter A Hall
    Department of Neurosurgery, University of Minnesota Medical School, Minneapolis, MN, USA
    J Magn Reson Imaging 27:368-75. 2008
    ..Mapping out neurologic function may influence the surgical approach to a tumor. The optimal strength for MR-guided neurosurgery is currently under investigation...
  44. ncbi Transsphenoidal surgery for acromegaly in wales: results based on stringent criteria of remission
    P De
    Department of Endocrinology, Metabolism, and Diabetes, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, United Kingdom
    J Clin Endocrinol Metab 88:3567-72. 2003
    ....
  45. pmc Contribution of intraoperative electrical stimulations in surgery of low grade gliomas: a comparative study between two series without (1985-96) and with (1996-2003) functional mapping in the same institution
    H Duffau
    Department of Neurosurgery, Hopital de la Salpetriere, Paris, France
    J Neurol Neurosurg Psychiatry 76:845-51. 2005
    ....
  46. pmc Insertion loads of the X STOP interspinous process distraction system designed to treat neurogenic intermittent claudication
    Vikram Talwar
    San Francisco Orthopaedic Residency Program, CA, USA
    Eur Spine J 15:908-12. 2006
    ..The significant relationship between BMD and spinous process failure load suggests that patients with lower BMD must be approached with more caution during the implant insertion procedure...
  47. ncbi Functional brain mapping and its applications to neurosurgery
    Suzanne Tharin
    Department of Neurosurgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Neurosurgery 60:185-201; discussion 201-2. 2007
    ..resolution anatomic and physiological data from multiple complementary sources will be used to plan more neurosurgical procedures, including minimally invasive procedures...
  48. pmc Intracranial low-grade gliomas in adults: 30-year experience with long-term follow-up at Mayo Clinic
    David A Schomas
    Department of Radiation Oncology, Mayo Clinic, Rochester, MN 55905, USA
    Neuro Oncol 11:437-45. 2009
    ..Postoperative RT was associated with improved OS and PFS and is recommended for patients after subtotal resection or biopsy...
  49. ncbi Long-term follow-up results of transsphenoidal surgery for Cushing's disease in a single centre using strict criteria for remission
    D A Rees
    Department of Endocrinology, Metabolism and Diabetes, University of Wales College of Medicine, Heath Park, Cardiff CF14 4XN, Wales, UK
    Clin Endocrinol (Oxf) 56:541-51. 2002
    ....
  50. ncbi Lateral supraorbital approach applied to anterior clinoidal meningiomas: experience with 73 consecutive patients
    Rossana Romani
    Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland
    Neurosurgery 68:1632-47; discussion 1647. 2011
    ..Anterior clinoidal meningiomas (ACMs) are a subgroup of meningiomas accounting for less than 10% of supratentorial meningiomas...
  51. ncbi Neurosurgical craniotomy localization using a virtual reality planning system versus intraoperative image-guided navigation
    Axel T Stadie
    Neurochirurgische Klinik und Poliklinik, Universitätsmedizin Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany
    Int J Comput Assist Radiol Surg 6:565-72. 2011
    ..Accurate craniotomy placement is essential for frameless neuronavigation in minimally invasive neurosurgery. A craniotomy using virtual reality (VR) can be as accurate as neuronavigation...
  52. ncbi Lateral supracerebellar transtentorial approach for petroclival meningiomas: operative technique and outcome
    Takao Watanabe
    Department of Neurological Surgery, Nihon University School of Medicine, Tokyo, Japan
    J Neurosurg 115:49-54. 2011
    ....
  53. ncbi Intraoperative subcortical electrical mapping of optic radiations in awake surgery for glioma involving visual pathways
    Guillaume Gras-Combe
    Department of Neurosurgery, Hopital Gui de Chauliac, Montpellier University Medical Center, Montpellier, France
    J Neurosurg 117:466-73. 2012
    ..The authors present, for the first time to their knowledge, a consecutive series of awake surgeries for cerebral glioma with intrasurgical identification and preservation of visual pathways using subcortical electrical mapping...
  54. ncbi Long-term outcome and survival of surgically treated supratentorial low-grade glioma in adult patients
    Rezvan Ahmadi
    Department of Neurosurgery, University of Heidelberg, INF 400, 69120 Heidelberg, Germany
    Acta Neurochir (Wien) 151:1359-65. 2009
    ..So far, there are no randomized studies that analyze the impact of surgical resection on patient outcome. The value of the data obtained from the few retrospective reports available is often limited...
  55. ncbi Anterior transpetrosal and subtemporal transtentorial approaches for pontine cavernomas
    Patrick Francois
    CHRU de Tours, Service de Neurochirurgie, Universite Francois Rabelais, Tours, France
    Acta Neurochir (Wien) 152:1321-9; discussion 1329. 2010
    ..We report our experience in the surgical management of these lesions exclusively using a lateral, subtemporal transtentorial approach in high pontine lesions and an anterior petrosal approach in low pontine lesions...
  56. ncbi Effect of the neurosurgeon's surgical experience on outcomes from intraoperative aneurysmal rupture
    Michael T Lawton
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    Neurosurgery 57:9-15; discussion 9-15. 2005
    ..Therefore, this analysis was undertaken to evaluate the effect of the neurosurgeon's experience on the management of this catastrophe in a consecutive series of patients treated microsurgically...
  57. ncbi Resective pediatric epilepsy surgery in Lennox-Gastaut syndrome
    Yun Jin Lee
    Department of Pediatrics, Pediatric Epilepsy Clinics, Severance Children s Hospital, Brain Research Institute, Yonsei University College of Medicine, Seoul, Korea
    Pediatrics 125:e58-66. 2010
    ..The objective of this study was to evaluate the role of resective pediatric epilepsy surgery for Lennox-Gastaut syndrome (LGS)...
  58. ncbi Intracavernous sinus arachnoid cyst with optic neuropathy
    Cheng Hsin Cheng
    Department of Neurosurgery, China Medical University Hospital, Taichung 404, Taiwan
    J Clin Neurosci 17:267-9. 2010
    ..Visual acuity improved dramatically after the operation. Intracavernous sinus arachnoid cyst is a rare congenital intracranial lesion and surgical decompression may benefit symptomatic patients...
  59. ncbi Incidence, timing, and treatment of new brain metastases after Gamma Knife surgery for limited brain disease: the case for reducing the use of whole-brain radiation therapy
    Stephen Rush
    Department of Radiation Oncology, New York University Langone Medical Center, 530 First Ave, Suite 8R, New York, New York 10016, USA
    J Neurosurg 115:37-48. 2011
    ....
  60. ncbi Impact of intraoperative stimulation brain mapping on glioma surgery outcome: a meta-analysis
    Philip C De Witt Hamer
    Neurosurgical Center Amsterdam, VU University Medical Center, Amsterdam, The Netherlands
    J Clin Oncol 30:2559-65. 2012
    ..The usefulness of intraoperative stimulation mapping (ISM) has not been addressed in randomized trials. This study addresses glioma surgery outcome on the basis of a meta-analysis of observational studies...
  61. ncbi Clinical management of petroclival meningiomas and the eternal quest for preservation of quality of life: personal experiences over a period of 20 years
    Volker Seifert
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Acta Neurochir (Wien) 152:1099-116. 2010
    ..Surgical concepts and the operative decision-making process are demonstrated in four illustrative cases...
  62. ncbi Long-term brain plasticity allowing a multistage surgical approach to World Health Organization Grade II gliomas in eloquent areas
    Santiago Gil Robles
    Department of Neurosurgery, Hopital Gui de Chauliac, Centre Hospitalier Universitaire de Montpellier, France
    J Neurosurg 109:615-24. 2008
    ..Based on their experience with these cases, the authors suggest that in cases of incomplete glioma removal, a second operation before anaplasia should be considered, made possible by brain reorganization after the first operation...
  63. ncbi Treatment of complex intracranial aneurysms of anterior circulation using multiple clips
    Hirotoshi Sano
    Department of Neurosurgery, Fujita Health University, 1 98 Dengakugakubo, Kutsukake cho, Toyoake, Aichi, Japan
    Acta Neurochir Suppl 107:27-31. 2010
    ..To evaluate the efficacy of multiple clip application for the occlusion of complex intracranial aneurysms, analyzing the technique and outcome of big and giant cerebral aneurysms clipped in our institution...
  64. ncbi Meningiomas involving the optic canal: pattern of involvement and implications for surgical technique
    Ahmed Nageeb M Taha
    Mansoura University Hospital, Mansoura Dakhlia, Egypt
    Neurosurg Focus 30:E12. 2011
    ..Juxtasellar meningiomas frequently extend into the optic canal. Removing these meningiomas from the optic canal is crucial for favorable visual outcome...
  65. pmc The sitting position during neurosurgical procedures does not influence serum biomarkers of pulmonary parenchymal injury
    Izabela Duda
    Department of Anesthesiology and Intensive Care, Medical University of Silesia, Medykow 14, Katowice, 40 75, Poland
    BMC Surg 12:24. 2012
    ..The aim of our study was to examine the hypothesis that the level of investigated pulmonary biomarkers in plasma is higher in patients operated on in the sitting position...
  66. ncbi Neurosurgical management of metastases in the central nervous system
    Elizabeth B Claus
    Yale University, School of Medicine, 60 College Street, New Haven, CT 06511, USA
    Nat Rev Clin Oncol 9:79-86. 2012
    ..that directly compare open surgical procedures with SRS are underway, as are trials examining the role of neurosurgical procedures, such as vertebroplasty and kyphoplasty, in association with radiotherapy as methods for pain control in ..
  67. ncbi The learning curve in endoscopic pituitary surgery and our experience
    Kenan Koc
    Department of Neurosurgery, Kocaeli University, School of Medicine, 41900 Izmit, Kocaeli, Turkey
    Neurosurg Rev 29:298-305; discussion 305. 2006
    ..Reviewing our cases in two groups of period due to our experience showed that the effectiveness of endoscopic surgery increases and operation time decreases. In our study, we identified a learning curve in endoscopic pituitary surgery...
  68. ncbi Diffuse scalp malignant peripheral nerve sheath tumor with intracranial extension in a patient with neurofibromatosis type 1
    Pengfei Ge
    Department of Neurosurgery, First Affiliated Hospital of Jilin University, 71 Xinmin Street, Changchun 130021, China
    J Clin Neurosci 17:1443-4. 2010
    ..Histological examination confirmed that the tumor was an MPNST. The patient recovered uneventfully and was well at the 6-month follow-up, with no local or other tumor recurrence noted...
  69. ncbi The reliability of neuroanatomy as a predictor of eloquence: a review
    Nader Pouratian
    Department of Neurosurgery, David Geffen School of Medicine at UCLA, Los Angeles, California 90095 7049, USA
    Neurosurg Focus 28:E3. 2010
    ..Perhaps most importantly, an individualized approach to mapping patients with brain tumors ensures that the risk of iatrogenic functional injury is minimized while maximizing the extent of resection...
  70. ncbi Etiology and management of hyponatremia in neurosurgical patients
    Urvashi M Upadhyay
    Department of Neurosugery, Brigham and Women s Hospital, Harvard Medical School, Boston, MA, USA
    J Intensive Care Med 27:139-44. 2012
    ..The rate at which serum sodium is corrected must be attended to, as rapid shifts in serum sodium pose potential risk of cerebral pontine myelinolysis...
  71. ncbi Morbidity following sural nerve harvesting: a prospective study
    Roberto S Martins
    Peripheral Nerve Surgery Unit, Department of Neurosurgery, Sao Paulo University, School of Medicine, Brazil
    Clin Neurol Neurosurg 114:1149-52. 2012
    ..To evaluate donor site morbidity following sural nerve harvesting, with special attention to the recovery of sensory loss...
  72. ncbi Venous air embolism: a warning not to be complacent--we should listen to the drumbeat of history
    Maurice S Albin
    Department of Anesthesiology, University of Alabama at Birmingham, Birmingham, Alabama, USA
    Anesthesiology 115:626-9. 2011
    ..Venous air embolism during neurosurgical procedures (detected by Doppler ultrasound and aspiration via a right atrial catheter) was noted in 100 of 400 ..
  73. ncbi Efficacy of endoport-guided endoscopic resection for deep-seated brain lesions
    Kwang Wook Jo
    Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University, School of Medicine, 50 Ir won dong, Kang Nam Ku, 135 71, Seoul, South Korea
    Neurosurg Rev 34:457-63. 2011
    ..This procedure required a protracted learning curve although, when successful, this approach can minimize brain retraction and provide satisfactory visualization...
  74. pmc Outcome and prognostic factors of hemicraniectomy for space occupying cerebral infarction
    E Uhl
    Department of Neurosurgery, Ludwig Maximilians University, Munich, Germany
    J Neurol Neurosurg Psychiatry 75:270-4. 2004
    ..functional outcome and length of survival of patients undergoing decompressive craniectomy for space occupying infarction of the middle cerebral artery (MCA), and to identify risk factors associated with death and unfavourable outcomes..
  75. ncbi End-to-side neurorrhaphy: past, present, and future
    Fausto Viterbo
    Discipline of Plastic Surgery at Botucatu School of Medicine, State University of Sao Paulo, Botucatu, Sao Paulo, Brazil
    Plast Reconstr Surg 124:e351-8. 2009
    ..She or he will also be able to expand on the existing experimental work in the pursuit of best functional outcomes...
  76. ncbi Presurgical simulation with advanced 3-dimensional multifusion volumetric imaging in patients with skull base tumors
    Makoto Oishi
    Department of Neurosurgery, Brain Research Institute, Niigata University, Niigata, Japan
    Neurosurgery 68:188-99; discussion 199. 2011
    ..Despite recent diagnostic and technical advancements in the field of neurosurgery, surgical treatment for tumors in the skull base region, ie, skull base tumors (SBTs), remains a challenge...
  77. ncbi Assessment of verbal working memory before and after surgery for low-grade glioma
    Pilar Teixidor
    Department of Neurosurgery, Hospital Germans Trias i Pujol, Ctra del Canyet s n, 08916, Badalona, Barcelona, Spain
    J Neurooncol 81:305-13. 2007
    ..We assessed verbal working memory (vWM) in patients with LGG in language areas, before and after surgery, to evaluate the effect of glioma and resection on cognition, respectively...
  78. ncbi Lateral supraorbital approach applied to tuberculum sellae meningiomas: experience with 52 consecutive patients
    Rossana Romani
    Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland
    Neurosurgery 70:1504-18; discussion 1518-9. 2012
    ..Various surgical approaches for the removal of tuberculum sellae meningiomas (TSMs) have previously been described...
  79. ncbi Virtual reality surgical anatomy of the sphenoid sinus and adjacent structures by the transnasal approach
    Shou Sen Wang
    Department of Neurosurgery, Fuzhou General Hospital, 156 Xihuanbei Road, Fuzhou 350025, China
    J Craniomaxillofac Surg 40:494-9. 2012
    ..To examine the three-dimensional virtual anatomical features of the sphenoid sinus and adjacent structures during virtual surgery and explore their relevance to actual transsphenoidal surgery...
  80. ncbi 10 pearls for safe endoscopic skull base surgery
    Madeleine R Schaberg
    Department of Otolaryngology, Weill Medical College of Cornell University, New York Presbyterian Hospital, 1305 York Avenue, Fifth Floor, New York, NY 10065, USA
    Otolaryngol Clin North Am 43:945-54. 2010
    ..This article presents the 10 most important tenets that have proved useful to the authors regarding postoperative patient management and surgical practice...
  81. ncbi Sham neurosurgical procedures in clinical trials for neurodegenerative diseases: scientific and ethical considerations
    Wendy R Galpern
    Office of Clinical Research, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 6001 Executive Blvd, 2225, Bethesda, MD 20892, USA
    Lancet Neurol 11:643-50. 2012
    ..Throughout the clinical development process, the perspectives of researchers, ethicists, and patients must be considered, and risks should be minimised whenever possible in a manner that is consistent with good trial design...
  82. ncbi Clinical variables related to propofol effect-site concentrations at recovery of consciousness after neurosurgical procedures
    Catarina S Nunes
    CECAV, Universidade de Trás os Montes de Alto Douro, Vila Real, Portugal
    J Neurosurg Anesthesiol 17:110-4. 2005
    ..Sixteen patients with a Glasgow of 15, ASA 1 or 2, subjected to neurosurgical procedures, received TIVA with TCI propofol and remifentanil...
  83. ncbi Surgery of low-grade gliomas: towards a 'functional neurooncology'
    Hugues Duffau
    Department of Neurosurgery, Hopital Gui de Chauliac, France
    Curr Opin Oncol 21:543-9. 2009
    ..Recently, new technical and conceptual advances in surgery have dramatically changed the management...
  84. ncbi Cerebrospinal fluid rhinorrhea following trans-sphenoidal pituitary macroadenoma surgery: experience from 592 patients
    Zong Li Han
    Department of Neurosurgery of the First Affiliated Hospital, Sun Yat Sen University, China
    Clin Neurol Neurosurg 110:570-9. 2008
    ..To determine the incidence, risk factors, diagnostic procedures, and management of cerebrospinal fluid (CSF) leaks following trans-sphenoidal pituitary macroadenoma surgery...
  85. ncbi Intraoperative MRI for interventional neurosurgical procedures and tumor resection control in children
    Paul Kremer
    Neurosurgical Department, University of Heidelberg, Heidelberg, Germany
    Childs Nerv Syst 22:674-8. 2006
    Despite the introduction of neuronavigational systems, radical tumor removal is still problematic in many neurosurgical procedures. Thus, direct intraoperative imaging for tumor resection control was implemented with an intraoperative ..
  86. ncbi Should stents be used in the treatment of ruptured intracranial aneurysms?
    C J O'Kelly
    Mackenzie Centre, Alberta, Canada
    J Neurosurg Sci 55:27-33. 2011
    ..One must weigh the potential hemorrhagic complications against the benefits of stent assisted coiling and the disadvantages of alternative approaches...
  87. ncbi Tailored anterior clinoidectomy through the lateral supraorbital approach: experience with 82 consecutive patients
    Rossana Romani
    Department of Neurosurgery, Helsinki University Central Hospital, Helsinki, Finland
    World Neurosurg 77:512-7. 2012
    ..We reviewed our recent experience on patients with vascular and tumor who underwent anterior clinoidectomy through the LSO approach...
  88. ncbi Waterjet dissection in neurosurgical procedures: clinical results in 35 patients
    Juergen Piek
    Department of Neurosurgery, Ernst Moritz Arndt University, Greifswald, Germany
    J Neurosurg 96:690-6. 2002
    ..This study was performed to investigate the clinical application of this new technique in neurosurgical procedures, such as brain tumor resection and epilepsy surgery.
  89. ncbi Fluoroscopic registration and localization for image-guided cranial neurosurgical procedures: a feasibility study
    Jaimie M Henderson
    Department of Neurosurgery, Stanford University, Stanford, California 94305, USA
    Stereotact Funct Neurosurg 86:271-7. 2008
    ..We also evaluated the accuracy of landmark placement in the fluoroscopic images using the navigational capability of the software...
  90. ncbi Brain surgery in a stereoscopic virtual reality environment: a single institution's experience with 100 cases
    Paolo Ferroli
    Department of Neurosurgery, Fondazione Istituto Neurologico Carlo Besta, Milan, Italy
    Neurosurgery 67:ons79-84; discussion ons84. 2010
    ..A comprehensive understanding of the spatial relationships between intracranial anatomy and pathological features is a crucial element in neurosurgical planning...
  91. ncbi Endoscopic management of skull base defects associated with persistent pneumocephalus following previous open repair: a preliminary report
    David W Clark
    Department of Otorhinolaryngology Head and Neck Surgery, Texas Sinus Institute, Texas Skull Base Institute, University of Texas at Houston Medical School, Houston, TX 77030, USA
    Otolaryngol Head Neck Surg 142:820-6. 2010
    ..To describe the management of anterior skull base defects in patients who present with pneumocephalus after previous open neurosurgical intervention...
  92. ncbi Repair of partial nerve injury by bypass nerve grafting with end-to-side neurorrhaphy
    Chunhui Song
    Department of Hand Surgery, Dalian Municipal Central Hospital, Dalian, China
    J Reconstr Microsurg 25:507-15. 2009
    ..End-to-side bypass nerve grafting can significantly improve functional recovery in the nerve with partial injury and may be a useful repair strategy in neuromas-in-continuity...
  93. pmc Surgical management and case-fatality rates of intracerebral hemorrhage in 1988 and 2005
    Opeolu Adeoye
    Department of Emergency Medicine, University of Cincinnati, Cincinnati, Ohio 45267 0525, USA
    Neurosurgery 63:1113-7; discussion 1117-8. 2008
    ..To compare surgical management and case-fatality rates of intracerebral hemorrhage (ICH) in 1988 and 2005...
  94. ncbi Risk factors for hemorrhagic presentation in patients with dural arteriovenous fistulae
    Vineeta Singh
    Department of Neurology, University of California at San Francisco, San Francisco, CA 94143, USA
    Neurosurgery 62:628-35; discussion 628-35. 2008
    ..The aim of this study was to investigate the independent effects of specific demographic and clinical variables on hemorrhagic presentation in patients with DAVFs...
  95. ncbi Survival and re-operation rates after neurosurgical procedures in Scotland: implications for targeted surveillance of sub-clinical variant Creutzfeldt-Jakob disease
    Sheila M Bird
    MRC Biostatistics Unit, Cambridge, UK
    Neuroepidemiology 33:1-11. 2009
    To assess the feasibility of post-mortem surveillance for subclinical variant Creutzfeldt-Jakob disease (vCJD) at least 5 years after neurosurgical procedures.
  96. ncbi The role of surgery for high-grade intracranial dural arteriovenous fistulas: importance of obliteration of venous outflow
    James K Liu
    Department of Neurological Surgery, Oregon Health and Science University, Portland, Oregon, USA
    J Neurosurg 110:913-20. 2009
    ..The authors report their 14-year experience with 23 patients harboring diverse intracranial DAVFs that required surgical intervention...
  97. ncbi Surgical treatment of high-risk intracranial dural arteriovenous fistulae: clinical outcomes and avoidance of complications
    Udaya K Kakarla
    Division of Neurological Surgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona 85013, USA
    Neurosurgery 61:447-57; discussion 457-9. 2007
    ..We reviewed our experience with the surgical management of high-risk intracranial DAVFs and offer recommendations to minimize complications based on fistula location and type...
  98. ncbi Propionibacterium acnes brain abscess appearing 10 years after neurosurgery
    Sarah M Kranick
    Hospital of University of Pennsylvania, Department of Neurology, 3 W Gates, 3400 Spruce St, Philadelphia, PA 19104, USA
    Arch Neurol 66:793-5. 2009
    ..To describe a case of Propionibacterium acnes infection arising 10 years after neurosurgery and to review the literature regarding similar cases and their treatment...
  99. ncbi Pituitary hormonal loss and recovery after transsphenoidal adenoma removal
    Nasrin Fatemi
    Brain Tumor Center, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, California 90404, USA
    Neurosurgery 63:709-18; discussion 718-9. 2008
    ..Transsphenoidal adenomectomy carries the possibility of new pituitary failure and recovery. Herein, we present rates and determinants of postoperative hormonal status...
  100. ncbi Propionibacterium acnes: an under-appreciated cause of post-neurosurgical infection
    M Nisbet
    Infectious Disease Department, Auckland City Hospital, Private Bag 92024, Auckland, New Zealand
    J Antimicrob Chemother 60:1097-103. 2007
    ..This review of patients with P. acnes neurosurgical infection was carried out in order to determine clinical characteristics and outcomes in relation to duration of antimicrobial treatment...
  101. ncbi Intraoperative diffusion-tensor MR imaging: shifting of white matter tracts during neurosurgical procedures--initial experience
    Christopher Nimsky
    Department of Neurosurgery, University Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Radiology 234:218-25. 2005
    To prospectively evaluate the location of white matter tracts with diffusion-tensor imaging (DTI) during neurosurgical procedures.

Research Grants62

  1. GENE DELIVERY TO THE CNS TO MODULATE EPILEPSY
    Samuel Rabkin; Fiscal Year: 2002
    ..Current neurosurgical procedures are highly invasive and often involve the removal of large areas of normal brain...
  2. Revitalizing Allografts for Craniofacial Reconstruction
    Edward Schwarz; Fiscal Year: 2007
    ..In addition, 30% of all major neurosurgical procedures involve craniotomy: 5% are the result of head trauma and 25% are not related to trauma...
  3. An image-guided neurosurgical workstation
    Paul Glimcher; Fiscal Year: 2007
    ..In the clinical arena, functional neurosurgical procedures can be combined with MRI information using image-guided neurosurgical workstations...
  4. Augmentation of Accuracy for Image-guided Neurosurgery
    Oskar Skrinjar; Fiscal Year: 2005
    ..Although the proposed methods will be applied to the microelectrode-guided surgery, they can be extended to other image-guided neurosurgical procedures, including tumor removal and epilepsy surgery.
  5. High Resolution EEG Source Imaging: Validation Study
    Bin He; Fiscal Year: 2005
    ..scalp electrical recordings and patients' magnetic resonance imaging (MRI), in patients undergoing neurosurgical procedures in a clinical setting...
  6. Transgenic Mice, Inflammation &the Alzheimer Phenotype
    Marcia N Gordon; Fiscal Year: 2012
    ..At present, the introduction of therapeutic genes to the brain has been limited to neurosurgical procedures which inject viral vectors directly into the brain...
  7. Mechanisms of Hyperbaric Oxygen Induced Brain Protection
    John H Zhang; Fiscal Year: 2013
    ..Vessel Occlusion (4VO);and a Surgical Brain Injury (SBI) model which represents brain injury caused by neurosurgical procedures. Based on these preliminary results demonstrating HIF-1 specifically responds to HBO, publications by us ..
  8. Cerebral Aneurysm Clipping Training Simulator using Virtual Reality and Haptics
    P Pat Banerjee; Fiscal Year: 2010
    ..If successful, following STTR Phases I and II, the ImmersiveTouch-SENSIMMER Neurosurgical Trainer will overcome challenges leading to evaluation of cerebral aneurysm clipping and other derivative neurosurgical procedures,
  9. Neurophysiological Basis of General Anesthesia
    ALEXANDER PROEKT; Fiscal Year: 2013
    ..Alexander Proekt, is an anesthesiologist specializing in caring for patients undergoing neurosurgical procedures. He has outlined a 5 year research plan that builds upon his background in neurophysiology and biophysics...
  10. Hemorrhage Control During Brain Surgery
    Weiliam Chen; Fiscal Year: 2010
    ..PUBLIC HEALTH RELEVANCE: Over 130,000 neurosurgical procedures are performed on the brain in the US each year...
  11. Neural Encoding and Connectivity in human speech perception
    BRIAN PASLEY; Fiscal Year: 2013
    ..functional organization of speech will allow more precise determination of critical speech sites during neurosurgical procedures and will provide insights into key brain areas and circuits underlying communication disorders such as ..
  12. Neocortical Mechanisms of Categorical Speech Perception
    Edward Chang; Fiscal Year: 2009
    ..speech processing by utilizing direct high-density ECoG recordings from the human neocortex during neurosurgical procedures. The principal focus of the mentored K99 phase will be to elucidate the emergent representation of ..
  13. Approach-specific, multi-GPU, multi-tool, high-realism neurosurgery simulation
    Dinesh Manocha; Fiscal Year: 2013
    ..of vasculature, as manipulation of vasculature is critical to tumor resection and many other neurosurgical procedures. In this Phase 2 project, we propose to extend and refine our simulator with additional components ..
  14. Augmented Reality Head Mounted Display for Magnetic Resonance Imaging Guided Inte
    Erez Nevo; Fiscal Year: 2013
    ..6. Conduct animal tests to evaluate the HMD in conducting percutaneous interventions and open neurosurgical procedures. The proposed project complies with two of the four specific goals of PA-10-079, namely: - The ..
  15. Diametrically Patterned Dural Graft for Enhanced Dura Mater Regeneration
    Shyam Patel; Fiscal Year: 2013
    ..a novel diametrically patterned nanofibrous dural substitute for rapid dura mater regeneration following neurosurgical procedures. In the US alone, 225,000 neurosurgical procedures are performed annually that require patching of the ..
  16. Robotic System for Minimally Invasive Neurosurgical Endoscopic Procedures
    JESSE MAXWELL LOCK; Fiscal Year: 2011
    ..Hospital Boston have assembled a team to create a minimally invasive robotic endoscope for neurosurgical procedures. The proposed robot will enable physicians to transcend the physical limitations of the human hand, and ..
  17. BIOGENIC AMINES AND NEUROLOGICAL DISORDERS
    Robert Katzman; Fiscal Year: 1980
    ..MHPG and dopamine-beta-hydroxylase) in lumbar and ventricular CSF in patients undergoing stereotaxic neurosurgical procedures. Clinical studies will focus on diseases in which there may be functional changes in aminergic activity, ..
  18. Bi-layered Diametrically Patterned Nanofibrous Dural Substitutes for Enhanced Dur
    Shyam Patel; Fiscal Year: 2012
    ..a novel diametrically patterned nanofibrous dural substitute for rapid dura mater regeneration following neurosurgical procedures. In the US alone, 225,000 neurosurgical procedures are performed annually that require patching of the ..
  19. Platform for MR-Guided Neurotherapeutic Drug Delivery
    EDWARD RAY BARKER; Fiscal Year: 2013
    ..therapy in the brain are critical for maximizing the effectiveness and safety during and following neurosurgical procedures. Magnetic resonance imaging (MRI) is a critical tool for planning and guiding neurosurgical procedures...
  20. Precision Freehand Sculpting for Skull Base
    Constantinos Nikou; Fiscal Year: 2009
    Skull base surgery is technically the most demanding of all of the neurosurgical procedures because of the intertwining of the hard, thick skull and delicate neural and vascular structures...
  21. BASAL GANGLIA FUNCTION--BASIC MECHANISMS AND EFFECTS
    JOHN ASSAD; Fiscal Year: 2004
    ..These questions are particularly relevant given the renewed interest in restorative neurosurgical procedures, such as chronic electrical stimulation. that target the BG to relieve Parkinsonian symptoms...
  22. Diffuse optical imaging of intracranial pressure changes
    Gary Strangman; Fiscal Year: 2004
    ..make continuous monitoring an important goal in at-risk populations, resulting in tens of thousands of neurosurgical procedures performed per year for such monitoring (AANS, 1999)...
  23. Pathophysiology of Dystonia
    Mahlon Delong; Fiscal Year: 2004
    ..models as wells as data from human subjects undergoing electrophysiologic, and neuroimaging studies and neurosurgical procedures will be discussed...
  24. NEONATAL ENCEPHALOPATHY TREATED BY MODERATE HYPOTHERMIA
    Dorothea Jenkins; Fiscal Year: 2001
    ..hypothermia during HI has been established in adult and neonatal populations undergoing cardiac and neurosurgical procedures. The safety and efficacy of longer-term systemic hypothermia (1-5 days) has been substantiated in adult ..
  25. ANESTHETIC PROTECTION OF HYPOXIC BRAIN TISSUE
    IRA KASS; Fiscal Year: 1991
    b>Neurosurgical procedures requiring general anesthesia put patients at risk of sustaining hypoxic-brain damage. Anesthetic agents that protect against hypoxia can prevent such damage...
  26. Software Guided Localization of the Subthalamic Nucleus During DBS Surgeries
    Peter Novak; Fiscal Year: 2010
    ..clinical electrophysiological workstation (FHC's Guideline 4000) for use in current functional neurosurgical procedures. PUBLIC HEALTH RELEVANCE: Project Narrative Deep brain stimulation of the subthalamic nucleus using ..
  27. CHARACTERIZATION OF SPONTANEOUSLY DIABETIC WISTAR RATS
    GLORIA TANNENBAUM; Fiscal Year: 1980
    ..modifications, including a) dietary restriction, b) diets high in sucrose, and c) hyperphagia induced by neurosurgical procedures, on the course of development of the diabetic syndrome. 4...
  28. Polymodal Electrode System for Intracranial Applications
    Lee Margolin; Fiscal Year: 2002
    ..As more functional neurosurgical procedures are performed each year, there is a growing need for new and innovative electrode technology that is ..
  29. INTERLEUKIN-1 IN BRAIN DEVELOPMENT AND INJURY
    DANA GIULIAN; Fiscal Year: 1993
    ..involving such techniques as tissue culture, immuno-histochemistry, protein purification, histology, and neurosurgical procedures. If successful, this proposed research will identify fundamental interactions between the immune and ..
  30. EXTRAMURAL RESEARCH FACILITIES CONSTRUCTION
    Dallas Hyde; Fiscal Year: 2003
    ..comprising an animal preparation area, a surgeon preparation suite and a surgery to accommodate extended neurosurgical procedures), a room for shared equipment (freezer, refrigerator, centrifuge), and a small preparation room for ..
  31. INTEGRATED IMAGING OPERATING MICROSCOPE
    Alexander Hartov; Fiscal Year: 1993
    ..It is believed that the commercial prospects of this project are very attractive given that any institution equipped to perform neurosurgical procedures will be a potential customer.
  32. Deep Brain Microelectrode Array For Functional Neurosurgery
    JAMILLE HETKE; Fiscal Year: 2006
    ..a leading supplier of intraoperative microelectrodes for recording and stimulation during functional neurosurgical procedures. [unreadable] [unreadable]
  33. Electrocorticographic Study of Categorical Phoneme Perception in the Human Tempor
    Edward Chang; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  34. COMPUTER-ASSISTED STEREOTAXIC NEUROSURGICAL SYSTEM
    ROBERT RIKER; Fiscal Year: 1990
    ..The modularity of design and the specific attention to use interface should make this system an defective tool in a wide variety of neurosurgical procedures.
  35. Purinergic control of medullary pain modulation
    Nathan Selden; Fiscal Year: 2006
    ..abstract_text> ..
  36. Intraoperative 3T MRI Scanner for Minimally Invasive Therapy
    Ferenc Jolesz; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  37. IMAGE GUIDED THERAPY CENTER
    Ferenc Jolesz; Fiscal Year: 2009
    ..abstract_text> ..
  38. Axon Plasticity and Recovery of Function after Traumatic Brain Injury
    Neil Harris; Fiscal Year: 2010
    ....
  39. Software Toolkit for Image Guided Surgery
    Kevin Cleary; Fiscal Year: 2005
    ..Dissemination activities will be undertaken with the aim of fostering the use of the toolkit in research and clinical applications. ..
  40. Intravascular Thrombosis in Glioblastoma
    Daniel Brat; Fiscal Year: 2005
    ..Our emerging model represents a paradigm shift in the understanding of GBM and should lead directly to more effective therapies. ..
  41. OR2020 Workshop: Operating Room of the Future
    Kevin Cleary; Fiscal Year: 2004
    ..The workshop is currently scheduled to be held from April 16-17, 2004, at Turf Valley Conference Center in Ellicot City, Maryland. ..
  42. Influence of subthalamic nucleus on striatal dopamine
    Thomas Wichmann; Fiscal Year: 2004
    ..These studies will provide insight into the role of the STN-SNc interaction under normal and parkinsonian conditions and will help to understand the mechanisms of action of neurosurgical treatments aimed at SIN in parkinsonian patients. ..
  43. In Vivo Imaging of Post-Traumatic Cerebral Amyloid Deposition
    Marvin Bergsneider; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  44. A HEMODYNAMIC MODEL OF INTRACRANIAL PRESSURE DYNAMICS
    Marvin Bergsneider; Fiscal Year: 2002
    ..An improved understanding of these disorders will offer new and better treatment modalities for millions of affected patients. ..
  45. NEURONAL CORRELATES OF HUMAN MEMORY
    George Ojemann; Fiscal Year: 2001
    ..This study, then, will more clearly define the subdivisions of human verbal memory and establish some of the changes in neural activity occurring with them. ..
  46. CT fluoroscopy guided robotically assisted lung biopsy
    Kevin Cleary; Fiscal Year: 2005
    ..The system will be validated in phantom and animal studies. The R33 phase will result in a system that is ready for clinical trials. ..
  47. Prostate Cancer Screening With Electrical Impedance Measurements
    Alexander Hartov; Fiscal Year: 2010
    ..We also will develop new electronics and reconstruction techniques applicable to this configuration. This project capitalizes on our group's extensive experience in impedance imaging. ..
  48. Early Randomized Surgical Epilepsy Trial
    Jerome Engel; Fiscal Year: 2007
    ..abstract_text> ..
  49. NABTC - M.D. Anderson Clinical Center
    Mark Gilbert; Fiscal Year: 2008
    ..The NABTC continues with the long-term goal of developing more effective treatments for patients with primary brain tumors, particularly malignant gliomas, combining longevity with the quality of survival. ..
  50. Endothelial progenitor cells and surgical outcomes
    Andrew Auerbach; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  51. Osmotherapy in Acute Ischemic Stroke
    Anish Bhardwaj; Fiscal Year: 2008
    ..abstract_text> ..
  52. CLINICAL NEUROSCIENCES TRAINING
    George Ojemann; Fiscal Year: 2008
    ..Four (4) post-doctoral and two (2) pre-doctoral trainees each year are requested, along with three (3) three-month short-term trainees. ..
  53. Cortical Excitability in Cocaine-Dependent Subjects
    Nashaat Boutros; Fiscal Year: 2009
    ..An additional exploratory aim is to probe the personality correlates of TMS-based cortical excitability changes in cocaine-dependent subjects. ..
  54. Function of dopamine in the primate substantia nigra
    Thomas Wichmann; Fiscal Year: 2009
    ..g., transplantation of ventral mesencephalic tissue) may act through local release of dopamine. ..
  55. Robotically Assisted Mouse Interventions
    Kevin Cleary; Fiscal Year: 2008
    ..3. Perform a feasibility study using 10 mice to demonstrate the ability of the robot to biopsy the mouse flank as selected on the MRI images and evaluate the accuracy of the system. [unreadable] [unreadable] [unreadable]..
  56. FUNCTIONAL MRI OF HUMAN BRAIN LANGUAGE SYSTEMS
    Jeffrey R Binder; Fiscal Year: 2010
    ..abstract_text> ..
  57. Neural correlates of memory fMR in human cortex.
    George Ojemann; Fiscal Year: 2006
    ..These studies provide a unique window into how neural activity is reflected in changes in BOLD fMR during higher-level cognitive measures. ..
  58. Intracranial Mapping of Sensory Gating in Humans
    Nashaat Boutros; Fiscal Year: 2006
    ..These data will shed more light on this crucial function and will help further our understanding of the mechanisms that lead to the development of psychotic disorders. ..
  59. Vaso-occlusive Mechanisms that Induce Hypoxia and Cause Glioma Progression.
    Daniel J Brat; Fiscal Year: 2010
    ..This proposal introduces entirely novel concepts that may explain the highly aggressive properties of GBM and suggests therapeutic approaches that could potentially stabilize its progression. ..
  60. In Vivo CSF Shunt Hydrodynamics in Hydrocephalus
    Marvin Bergsneider; Fiscal Year: 2010
    ..Documenting definitive evidence of the tuned-dynamic absorber model could have fundamental implications to all ICP disorders. ..
  61. Local field potentials in the basal ganglia
    THOMAS N WICHMANN; Fiscal Year: 2010
    ..Conceivably, such criteria could be used in the next generation of DBS devices to trigger 'on-demand'stimulation. ..
  62. MN REGIONAL SLEEP DISORDERS CENTER SLEEP ACADEMIC AWARD
    Gerald Rosen; Fiscal Year: 2002
    ....