minimally invasive surgical procedures

Summary

Summary: Procedures that avoid use of open invasive surgery in favor of closed or local surgery. These generally involve use of laparoscopic devices and remote-control manipulation of instruments with indirect observation of the surgical field through an endoscope or similar device. With the reduced trauma associated with minimally invasive surgery, long hospital stays may be reduced with increased rates of short stay or day surgery.

Top Publications

  1. ncbi Minimally invasive video-assisted parathyroidectomy versus open minimally invasive parathyroidectomy for a solitary parathyroid adenoma: a prospective, randomized, blinded trial
    Marcin Barczynski
    Department of Endocrine Surgery, 3rd Chair of General Surgery, Jagiellonian University College of Medicine, 37 Pradnicka Street, Krakow, 31 202, Poland
    World J Surg 30:721-31. 2006
  2. ncbi Minimally invasive valve surgery
    Y Joseph Woo
    Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Semin Thorac Cardiovasc Surg 19:289-98. 2007
  3. ncbi Minimally invasive liver resection for metastatic colorectal cancer: a multi-institutional, international report of safety, feasibility, and early outcomes
    Kevin Tri Nguyen
    Department of Surgery, Division of Transplantation, University of Pittsburgh, Pittsburgh, PA, USA
    Ann Surg 250:842-8. 2009
  4. ncbi Early radiographic and clinical results of balloon kyphoplasty for the treatment of osteoporotic vertebral compression fractures
    Frank M Phillips
    The University of Chicago Spine Center, Chicago, Illinois, USA
    Spine (Phila Pa 1976) 28:2260-5; discussion 2265-7. 2003
  5. ncbi Robotics in general surgery: personal experience in a large community hospital
    Pier Cristoforo Giulianotti
    Department of General Surgery, Misericordia Hospital, Grosseto, Italy
    Arch Surg 138:777-84. 2003
  6. ncbi The operation of the century: total hip replacement
    Ian D Learmonth
    Department of Orthopaedics, Bristol Royal Infirmary, Bristol BS2 8HW, UK
    Lancet 370:1508-19. 2007
  7. ncbi Randomized controlled trial comparing the radiologic outcomes of conventional and minimally invasive techniques for total knee arthroplasty
    Pak Lin Chin
    Department of Orthopedic Surgery, Singapore General Hospital, Singapore City, Republic of Singapore
    J Arthroplasty 22:800-6. 2007
  8. ncbi Minimally invasive total hip arthroplasty. Development, early results, and a critical analysis. Presented at the Annual Meeting of the American Orthopaedic Association, Charleston, South Carolina, USA, June 14, 2003
    Daniel J Berry
    Mayo Clinic, 200 First Street S W, Rochester, MN 55905, USA
    J Bone Joint Surg Am 85:2235-46. 2003
  9. ncbi Impact of pectus excavatum on pulmonary function before and after repair with the Nuss procedure
    M Louise Lawson
    Center for Pediatric Research, Children s Hospital of The King s Daughters and Eastern Virginia Medical School, Norfolk, VA 23507, USA
    J Pediatr Surg 40:174-80. 2005
  10. ncbi A minimal-incision technique in total hip arthroplasty does not improve early postoperative outcomes. A prospective, randomized, controlled trial
    Luke Ogonda
    Orthopaedic Outcomes Unit, Musgrave Park Hospital, Stockmans Lane, Belfast BT9 7JB, Northern Ireland, United Kingdom
    J Bone Joint Surg Am 87:701-10. 2005

Detail Information

Publications233 found, 100 shown here

  1. ncbi Minimally invasive video-assisted parathyroidectomy versus open minimally invasive parathyroidectomy for a solitary parathyroid adenoma: a prospective, randomized, blinded trial
    Marcin Barczynski
    Department of Endocrine Surgery, 3rd Chair of General Surgery, Jagiellonian University College of Medicine, 37 Pradnicka Street, Krakow, 31 202, Poland
    World J Surg 30:721-31. 2006
    ..This study aimed at comparing the video-assisted MIP (MIVAP) and open MIP (OMIP) in a prospective, randomized, blinded trial...
  2. ncbi Minimally invasive valve surgery
    Y Joseph Woo
    Department of Surgery, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Semin Thorac Cardiovasc Surg 19:289-98. 2007
    ..Finally, unique situations such as pulmonic valve surgery, reoperations, beating heart surgery, and robotics are discussed...
  3. ncbi Minimally invasive liver resection for metastatic colorectal cancer: a multi-institutional, international report of safety, feasibility, and early outcomes
    Kevin Tri Nguyen
    Department of Surgery, Division of Transplantation, University of Pittsburgh, Pittsburgh, PA, USA
    Ann Surg 250:842-8. 2009
    ..To evaluate a multicenter, international series on minimally invasive liver resection for colorectal carcinoma (CRC) metastasis...
  4. ncbi Early radiographic and clinical results of balloon kyphoplasty for the treatment of osteoporotic vertebral compression fractures
    Frank M Phillips
    The University of Chicago Spine Center, Chicago, Illinois, USA
    Spine (Phila Pa 1976) 28:2260-5; discussion 2265-7. 2003
    ..A prospective consecutive cohort study of clinical and radiographic outcomes after kyphoplasty for treatment of osteoporotic vertebral compression fractures...
  5. ncbi Robotics in general surgery: personal experience in a large community hospital
    Pier Cristoforo Giulianotti
    Department of General Surgery, Misericordia Hospital, Grosseto, Italy
    Arch Surg 138:777-84. 2003
    ..Robotic technology is the most advanced development of minimally invasive surgery, but there are still some unresolved issues concerning its use in a clinical setting...
  6. ncbi The operation of the century: total hip replacement
    Ian D Learmonth
    Department of Orthopaedics, Bristol Royal Infirmary, Bristol BS2 8HW, UK
    Lancet 370:1508-19. 2007
    ..Universal economic constraints in healthcare services dictate that further developments in total hip replacement will be governed by their cost-effectiveness...
  7. ncbi Randomized controlled trial comparing the radiologic outcomes of conventional and minimally invasive techniques for total knee arthroplasty
    Pak Lin Chin
    Department of Orthopedic Surgery, Singapore General Hospital, Singapore City, Republic of Singapore
    J Arthroplasty 22:800-6. 2007
    ..The side cut group also had more outliers in the coronal plane. Results were comparable between the mini and control groups. The side cut technique appears to affect the accuracy of implant placement...
  8. ncbi Minimally invasive total hip arthroplasty. Development, early results, and a critical analysis. Presented at the Annual Meeting of the American Orthopaedic Association, Charleston, South Carolina, USA, June 14, 2003
    Daniel J Berry
    Mayo Clinic, 200 First Street S W, Rochester, MN 55905, USA
    J Bone Joint Surg Am 85:2235-46. 2003
  9. ncbi Impact of pectus excavatum on pulmonary function before and after repair with the Nuss procedure
    M Louise Lawson
    Center for Pediatric Research, Children s Hospital of The King s Daughters and Eastern Virginia Medical School, Norfolk, VA 23507, USA
    J Pediatr Surg 40:174-80. 2005
    ....
  10. ncbi A minimal-incision technique in total hip arthroplasty does not improve early postoperative outcomes. A prospective, randomized, controlled trial
    Luke Ogonda
    Orthopaedic Outcomes Unit, Musgrave Park Hospital, Stockmans Lane, Belfast BT9 7JB, Northern Ireland, United Kingdom
    J Bone Joint Surg Am 87:701-10. 2005
    ..The objective of this study was to compare the results of a single mini-incision approach with those of a standard-incision total hip arthroplasty in the early postoperative period...
  11. ncbi Mediastinitis and cardiac surgery--an updated risk factor analysis in 10,373 consecutive adult patients
    J F Gummert
    Klinik für Herzchirurgie GmbH, Universitat Leipzig, Herzzentrum Leipzig GmbH and
    Thorac Cardiovasc Surg 50:87-91. 2002
    ....
  12. ncbi Minimally invasive video-assisted thyroidectomy for papillary carcinoma: a prospective study of its completeness
    Paolo Miccoli
    Department of Surgery, University of Pisa, S Chiara Hospital, Via Roma 67, 56100 Pisa, Italy
    Surgery 132:1070-3; discussion 1073-4. 2002
    ..Some are concerned about this procedure in patients with thyroid cancer. This prospective study aimed to demonstrate that near-total thyroidectomy can be performed by MIVAT with similar results compared with open thyroidectomy...
  13. ncbi Minimally invasive surgery for thyroid small nodules: preliminary report
    P Miccoli
    Surgery Department, University of Pisa, Italy
    J Endocrinol Invest 22:849-51. 1999
    ..No complications were registered. Cosmetical result was excellent in all patients. MIVA hemythyroidectomy is safe and effective; indications and limits of this new procedure require further studies...
  14. ncbi Repair of the pectus deformity: results of the Ravitch approach in the current era
    J Terrance Davis
    Department of Cardiothoracic Surgery, Columbus Children s Hospital, ED 620 Education Building, 700 Children s Drive, Columbus, OH 43221, USA
    Ann Thorac Surg 78:421-6. 2004
    ..Efforts to evaluate this new approach have been hampered by lack of comparative information regarding outcomes of the standard Ravitch approach. We use a modified Ravitch procedure, and present our series as a basis for comparison...
  15. ncbi Modified sutureless sclerotomies in pars plana vitrectomy
    A K Kwok
    Department of Ophthalmology and Visual Sciences, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin
    Am J Ophthalmol 127:731-3. 1999
    ..To study the effectiveness and safety of a modified sutureless sclerotomy technique in pars plana vitrectomy...
  16. ncbi Minimally invasive correction of pectus excavatum in adult patients
    Johannes Schalamon
    Department of Pediatric Surgery, Medical University of Graz, Austria
    J Thorac Cardiovasc Surg 132:524-9. 2006
    ..Studies on adult patients are rare. We analyzed the efficacy of minimally invasive pectus repair in a series of adult patients...
  17. ncbi Sutureless 25-gauge vitrectomy: risky or rewarding?
    Adam Martidis
    Ophthalmology 114:2131-2. 2007
  18. ncbi Pectus excavatum repair: experience with standard and minimal invasive techniques
    K A Molik
    Section of Pediatric Surgery, Indiana University School of Medicine and the J.W. Riley Hospital for Children, Indianapolis, IN 46202, USA
    J Pediatr Surg 36:324-8. 2001
    ..Long-term follow-up will be necessary to determine final cosmetic and functional outcomes and define the overall risks and benefits of this procedure as compared with the standard technique...
  19. ncbi Preliminary outcomes and efficacy of the first 360 consecutive kyphoplasties for the treatment of painful osteoporotic vertebral compression fractures
    Mohammad E Majd
    Spine Surgery, PSC, 210 E Gray Street, Suite 601, Louisville, KY 40202, USA
    Spine J 5:244-55. 2005
    ..Kyphoplasty involves expanding an inflatable balloon tamp to create a cavity within a vertebral body before cement deposition...
  20. ncbi Does robotic assistance improve efficiency in performing complex minimally invasive surgical procedures?
    Shiva Jayaraman
    CSTAR Canadian Surgical Technologies and Advanced Robotics, Lawson Health Research Institute, London, ON, Canada
    Surg Endosc 24:584-8. 2010
    ..We used a model of biliary-enteric anastomosis to test whether da Vinci robotics improves performance on a complex minimally invasive surgical (MIS) procedure...
  21. ncbi Transforaminal posterolateral endoscopic discectomy with or without the combination of a low-dose chymopapain: a prospective randomized study in 280 consecutive cases
    Thomas Hoogland
    Department of Spine Surgery, Alpha Klinik Munich, Munich, Germany
    Spine (Phila Pa 1976) 31:E890-7. 2006
    ....
  22. ncbi Experience in 100 cases with the Nuss procedure using a technique for stabilization of the pectus bar
    Sadashige Uemura
    Department of Pediatric Surgery, Iwakuni National Hospital, 2 5 1, Kuroiso, 740 8510 Iwakuni, Japan
    Pediatr Surg Int 19:186-9. 2003
    ..Teen-aged patients, however, were at high risk of bar displacement. Therefore, the use of two bars and lateral stabilizing bars are recommended for these high-risk patients...
  23. ncbi Mini-incision total hip arthroplasty: a comparative assessment of perioperative outcomes
    James F Wenz
    Department of Orthopedic Surgery, The Johns Hopkins University Johns Hopkins Bayview Medical Center, Baltimore, MD 21224 2780, USA
    Orthopedics 25:1031-43. 2002
    ..This procedure achieved accurate and reproducible implantation, regardless of patient habitus...
  24. ncbi Minimal access surgery (MAS)-related surgeon morbidity syndromes
    D A G Reyes
    Cuschieri Skills Centre, Ninewells Hospital and Medical School, University of Dundee, Dundee, DD1 9SY, Scotland, United Kingdom
    Surg Endosc 20:1-13. 2006
    ..Only improved knowledge of the etiology and underlying ergonomic factors based on investigative studies followed by improved instrumentation and operating room (OR) ergonomics will provide near- and long-term solutions...
  25. ncbi Outcomes of 140 consecutive cases of 25-gauge transconjunctival surgery for posterior segment disease
    Rohit R Lakhanpal
    Doheny Retina Institute, Doheny Eye Institute, Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Ophthalmology 112:817-24. 2005
    ..To evaluate the safety and efficacy of 25-gauge instrumentation for a variety of vitreoretinal conditions on previously nonvitrectomized eyes...
  26. ncbi Comparing minimally invasive funnel chest repair versus the conventional technique: an outcome analysis in children
    Roland A Boehm
    Department of Pediatric Surgery, Children s Hospital, University of Munich, Munich, Germany
    Plast Reconstr Surg 114:668-73; discussion 674-5. 2004
    ..In well-selected patients (age, symmetric deformity), the Nuss procedure may become the method of choice. However, there is still a lack of long-term follow-up...
  27. ncbi Minimally invasive mitral valve repair suggests earlier operations for mitral valve disease
    James P Greelish
    Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
    J Thorac Cardiovasc Surg 126:365-71; discussion 371-3. 2003
    ..To validate this approach we reviewed our entire experience through May 2002...
  28. ncbi Minimally invasive approach to the cervical spine: a proposal
    P Miccoli
    Department of Surgery, University of Pisa, Italy
    J Laparoendosc Adv Surg Tech A 11:89-92. 2001
    ..Because of the good exposure of the cervical spine during these procedures, the authors decided to perform an anatomic-radiologic study in order to evaluate which cervical vertebrae could be reached by this minimally invasive approach...
  29. ncbi A new 25-gauge instrument system for transconjunctival sutureless vitrectomy surgery
    Gildo Y Fujii
    Microsurgery Advanced Design Laboratory, Doheny Eye Institute, University of Southern California, Keck School of Medicine, Los Angeles, California 90033, USA
    Ophthalmology 109:1807-12; discussion 1813. 2002
    ..To introduce and evaluate the infusion and aspiration rates and operative times of the 25-gauge transconjunctival sutureless vitrectomy system (TSV) DESIGN: In vitro experimental and comparative interventional study...
  30. ncbi Minimally invasive surgical training solutions for the twenty-first century
    J C Rosser
    Yale Endo Laparoscopic Center, Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06511, USA
    Surg Clin North Am 80:1607-24. 2000
    ..A high priority must be placed on the resolution of these issues...
  31. ncbi Video-assisted thyroid lobectomy through a small wound in the submandibular area
    Hiroyuki Yamashita
    Noguchi Thyroid Clinic and Hospital Foundation, 6 33 Noguchi Nakamachi, 874 0932, Beppu Oita, Japan
    Am J Surg 183:286-9. 2002
    ..We developed a video-assisted hemithyroidectomy procedure that requires only one small incision at the upper neck...
  32. ncbi An extreme lateral access for the surgery of lumbar disc herniations inside the spinal canal using the full-endoscopic uniportal transforaminal approach-technique and prospective results of 463 patients
    Sebastian Ruetten
    Department for Spine Surgery and Pain Therapy, Clinic for Orthopaedics and Traumatology, St Anna Hospital, Herne, Germany
    Spine (Phila Pa 1976) 30:2570-8. 2005
    ..Prospective study of patients with lumbar disc herniations who were operated on with a full-endoscopic uniportal transforaminal approach using an extreme lateral access...
  33. ncbi Early and late outcomes in minimally invasive mitral valve repair: an eleven-year experience in 707 patients
    R Scott McClure
    Brigham and Women s Hospital, Division of Cardiac Surgery, Harvard School of Public Health, Department of Epidemiology, Boston, MA 02115, USA
    J Thorac Cardiovasc Surg 137:70-5. 2009
    ..Late follow-up of mitral regurgitation and left ventricular function were also assessed...
  34. ncbi Role of navigation in total hip arthroplasty
    Todd C Kelley
    Department of Orthopaedics, University of Cincinnati, 231 Albert Sabin Way, Cincinnati, OH 45267 0212, USA
    J Bone Joint Surg Am 91:153-8. 2009
    ....
  35. ncbi [Minimally invasive total hip arthroplasty. Anterior approach]
    F Rachbauer
    Universitätsklinik für Orthopädie, Medizinische Universitat Innsbruck, Anichstrasse 35, A 6020, Innsbruck, Austria
    Orthopade 35:723-4, 726-9. 2006
    ..The procedure leads to cosmetically pleasing scars. As the patients usually do not suffer from considerable postoperative pain and experience accelerated rehabilitation, they agree to early discharge...
  36. ncbi Muscle damage during MIS total hip arthroplasty: Smith-Petersen versus posterior approach
    R Michael Meneghini
    Department of Orthopaedic Surgery, Mayo Clinic, Rochester, MN, USA
    Clin Orthop Relat Res 453:293-8. 2006
    ..Clinical outcome studies and gait analysis are necessary to ascertain the functional implications of these findings...
  37. ncbi Minimally invasive surgery compared to open procedures in esophagectomy for cancer: a systematic review of the literature
    R J J Verhage
    Department of Surgery, University Medical Center Utrecht, Utrecht, The Netherlands
    Minerva Chir 64:135-46. 2009
    ..Moreover, the retrieved studies collectively point towards improved short term outcomes after MIE. These results should be confirmed in randomized controlled trials...
  38. ncbi Minimally invasive total knee arthroplasty compared with traditional total knee arthroplasty. Assessment of the learning curve and the postoperative recuperative period
    Jason King
    Department of Orthopaedics and Sports Medicine, University of Washington Medical Center, 1959 N E Pacific Street, Box 356500, Seattle, WA 98005, USA
    J Bone Joint Surg Am 89:1497-503. 2007
    ....
  39. ncbi The early clinical outcome of minimally invasive quadriceps-sparing total knee arthroplasty: report of a 2-year follow-up
    Hsuan Ti Huang
    Department of Orthopedics, Kaohsiung Medical University, Kaohsiung, Taiwan
    J Arthroplasty 22:1007-12. 2007
    ..The Q-S technique showed better and faster recovery, but there were more outliers and bone injuries during surgery, and this coupled with length of tourniquet time were the major disadvantages in our early experience...
  40. ncbi Incidence of endophthalmitis after 20- and 25-gauge vitrectomy
    Derek Y Kunimoto
    Retina Service, Wills Eye Hospital, Jefferson Medical College of Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    Ophthalmology 114:2133-7. 2007
    ..To assess the incidence rate of endophthalmitis after 25-gauge pars plana vitrectomy and to compare it with the endophthalmitis rate after 20-gauge pars plana vitrectomy...
  41. ncbi Treatment of Zenker's diverticulum through a flexible endoscope with a transparent oblique-end hood attached to the tip and a monopolar forceps
    P Christiaens
    Department of Internal Medicine and Gastroenterology, Imeldaziekenhuis Bonheiden, Belgium
    Endoscopy 39:137-40. 2007
    ..In our single-center study we report the safety and feasibility of endoscopic myotomy through a flexible endoscope, performed at a secondary referral centre...
  42. ncbi Hindfoot endoscopy for posterior ankle impingement. Surgical technique
    C N van Dijk
    Department of Orthopaedic Surgery, Academic Medical Center, Amsterdam, The Netherlands
    J Bone Joint Surg Am 91:287-98. 2009
    ..An endoscopic approach to the posterior ankle (hindfoot endoscopy) may lack these disadvantages. We hypothesized that hindfoot endoscopy causes less morbidity and facilitates a quick recovery compared with open surgery...
  43. ncbi Comparison of primary total hip arthroplasties performed with a minimally invasive technique or a standard technique: a prospective and randomized study
    Young Hoo Kim
    The Joint Replacement Center of Korea, Ewha Womans University College of Medicine, Seoul, Korea
    J Arthroplasty 21:1092-8. 2006
    ..There were no any late transfusions in any of our patients postdischarge. This minimally invasive technique did not offer any advantages because the results were not different, and in our hands, it increased our infection rate...
  44. ncbi Comparative radiologic evaluation of percutaneous endoscopic lumbar discectomy and open microdiscectomy: a matched cohort analysis
    Sang Ho Lee
    Department of Neurosurgery, Wooridul Spine Hospital, 47 4 Chungdam dong, Kangnam Gu, Seoul, Korea
    Mt Sinai J Med 73:795-801. 2006
    ..The purpose of this study was to compare the radiographic changes in patients treated with percutaneous endoscopic lumbar discectomy (PELD) with those of patients treated with open lumbar microdiscectomy (OLM)...
  45. ncbi Minimally-invasive treatment of intra-articular fractures of the calcaneum
    J Stulik
    Spinal Surgery Unit, University Hospital Motol, V, Uvalu 84, Prague, Czech Republic
    J Bone Joint Surg Br 88:1634-41. 2006
    ..9%) were able to return to their original occupation at a mean of 5.6 months (3.2 to 12.5) after the injury. Semi-open reduction and percutaneous fixation is an effective treatment for displaced intra-articular fractures of the calcaneum...
  46. ncbi Experience and modification update for the minimally invasive Nuss technique for pectus excavatum repair in 303 patients
    Daniel P Croitoru
    Department of Surgery, Children s Hospital of the King s Daughters, Norfolk, VA, USA
    J Pediatr Surg 37:437-45. 2002
    ..The aim of this study is to review the new technical modifications and results of 303 patients who have had pectus excavatum repair utilizing the minimally invasive technique...
  47. ncbi Minimally invasive abdominal surgery: lux et veritas past, present, and future
    Andrew G Harrell
    Division of Gastrointestinal and Minimally Invasive Surgery, Carolinas Hernia Institute, Carolinas Medical Center, 1000 Blythe Blvd, MEB 601, Charlotte, NC 28203, USA
    Am J Surg 190:239-43. 2005
    ..As the instrumentation became more advanced, the application of this technique followed. By revisiting the historical developments that now define laparoscopic surgery, we can possibly foresee its future...
  48. ncbi Quality of life and surgical outcome after total laparoscopic hysterectomy versus total abdominal hysterectomy for benign disease: a randomized, controlled trial
    Kirsten B Kluivers
    Department of Obstetrics and Gynecology, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Minim Invasive Gynecol 14:145-52. 2007
    ..None of these studies evaluated total laparoscopic hysterectomy. In this paper, we report on a randomized comparison of quality of life after total laparoscopic versus total abdominal hysterectomy...
  49. ncbi Combined thoracoscopic and endoscopic management of mid-esophageal benign lesions: use of the prone patient position : Thoracoscopic surgery for mid-esophageal benign tumors and diverticula
    Chinnusamy Palanivelu
    GEM Hospital, 45 A, Pankaja Mill Road, Ramnathapuram, Coimbatore, 641045, India
    Surg Endosc 22:250-4. 2008
    ..Traditionally, thoracotomy was the preferred route to approach these lesions. Now, more surgeons are using minimally invasive techniques to treat these benign mid-esophageal lesions...
  50. ncbi Early pain relief and function after posterior minimally invasive and conventional total hip arthroplasty. A prospective, randomized, blinded study
    Lawrence D Dorr
    The Arthritis Institute, 501 East Hardy Street, 3rd Floor, Inglewood, CA 90301, USA
    J Bone Joint Surg Am 89:1153-60. 2007
    ....
  51. ncbi Difficulties and limitations in minimally invasive repair of pectus excavatum--6 years experiences with Nuss technique
    Jozef Dzielicki
    Department of Pediatric Surgery, Silesian Medical University, Minimally Invasive Surgery Center for Adults and Children, University Hospital No 1, 3 Maja 13 15, 41 800 Zabrze, Poland
    Eur J Cardiothorac Surg 30:801-4. 2006
    ..The paper aims at presenting the authors' own 6 years of experience in funnel chest repair with MIRPE technique. Also, many technical problems of this method are discussed...
  52. ncbi Survival of self-etch adhesive Class II composite restorations using ART and conventional cavity preparations in primary molars
    Ece Eden
    Department of Paediatric Dentistry, Ege University, School of Dentistry, Izmir, Turkey
    Am J Dent 19:359-63. 2006
    ..To test the null-hypothesis that there was no difference in the survival percentages of Class II composite restorations in primary teeth produced through either ART or conventional approaches after 2 years...
  53. pmc Sutureless vitrectomy
    Sunil K Warrier
    Retina Unit, South Australian Institute of Ophthalmology and Discipline of Ophthalmology and Visual Sciences, University of Adelaide, South Australia
    Indian J Ophthalmol 56:453-8. 2008
    ..A literature review was undertaken using 'Medline' and 'Pubmed'. Search terms included sutureless vitrectomy, 20 gauge, 23 gauge, 25 gauge, and transconjunctival and small gauge vitrectomy...
  54. ncbi Leg wound infections following greater saphenous vein harvesting: minimally invasive vein harvesting versus conventional vein harvesting
    James F Reed
    Academic Affairs, Christiana Care Hospital System, Newark, Delaware 19718 6001, USA
    Int J Low Extrem Wounds 7:210-9. 2008
    ..A visual inspection of "funnel" plots suggests a mild to moderate publication bias. This meta-analysis suggests that leg wound infections and wound healing disturbances are reduced using MIVH techniques...
  55. ncbi Minimally invasive colorectal resection outcomes: short-term comparison with open procedures
    J Kay Noel
    United BioSource Corporation formerly MetaWorks, Inc, Medford, MA 02155, USA
    J Am Coll Surg 204:291-307. 2007
  56. ncbi Less invasive total hip arthroplasty: description of a new technique
    Riaz J K Khan
    Department of Surgery and Pathology, University of Western Australia, Perth, Western Australia, Australia
    J Arthroplasty 21:1038-46. 2006
    ..0001). There was greater improvement in WOMAC scores for up to 1 year in the less invasive group (P = .027). In conclusion, the less invasive approach is safe and the functional benefits last up to 1 year...
  57. ncbi Clinical experience using a minimally invasive surgical approach for total knee arthroplasty: early results of a prospective randomized study compared to a standard approach
    Frank R Kolisek
    OrthoIndy, Indiania Orthopaedic Surgery Center, Indianapolis, Indiana, USA
    J Arthroplasty 22:8-13. 2007
    ..At 12 weeks follow-up, there was no difference in mean Knee Society objective and functional scores. In summary, in this study, minimal incision total knee arthroplasty demonstrated no improvement over a standard approach...
  58. ncbi Perioperative sargramostim (recombinant human GM-CSF) induces an increase in the level of soluble VEGFR1 in colon cancer patients undergoing minimally invasive surgery
    I Kirman
    College of Physicians and Surgeons of Columbia University, Department of Surgery, 630 West 168th Street, New York, NY 10032, USA
    Eur J Surg Oncol 33:1169-76. 2007
    ..This study's purpose was to determine the impact of perioperatively administered recombinant human GMCSF (rhu-GMCSF) on both immune function and plasma sVEGFR1 levels in colorectal cancer patients...
  59. pmc Computer navigation-assisted versus minimally invasive TKA: benefits and drawbacks
    Peter M Bonutti
    Bonutti Clinic, Effingham, IL, USA
    Clin Orthop Relat Res 466:2756-62. 2008
    ..We believe the higher incidence of complications in addition to the longer operative time in the navigated group may outweigh any potential radiographic benefits...
  60. ncbi Two hundred forty minimally invasive mitral operations through right minithoracotomy
    Tayfun Aybek
    Department for Thoracic and Cardiovascular Surgery, Johann Wolfgang Goethe University, Frankfurt Main, Germany
    Ann Thorac Surg 81:1618-24. 2006
    ..This study reports of our 7-year experience with minimally invasive mitral valve operations using the transthoracic clamp technique, reviewing morbidity and mortality as well as echocardiographic follow-up results...
  61. ncbi Minimally invasive quadriceps-sparing TKA: results of a comprehensive pathway for outpatient TKA
    Richard A Berger
    Department of Orthopedic Surgery, Rush Medical College, Rush Presbyterian St Luke s Medical Center, Chicago, IL 60612, USA
    J Knee Surg 19:145-8. 2006
  62. ncbi Minimally invasive anterolateral approach to the hip: risk to the superior gluteal nerve
    Akif Ince
    Department of Orthopaedics, University Hospital of Wurzburg, Germany
    Acta Orthop 78:86-9. 2007
    ..Minimally invasive approaches to the hip show promise of less muscle trauma compared to conventional approaches. What is the risk of damage to the superior gluteal nerve? We studied the course of the superior gluteal nerve...
  63. ncbi Minimally invasive transhiatal esophagectomy: lessons learned
    Grant Sanders
    Department of Gastrointestinal Surgery, St Eloi hospital, University Hospital of Montpellier, Montpellier, France
    Surg Endosc 21:1190-3. 2007
    ..This report details our experience with this technique and the lessons we have learned...
  64. ncbi [Comparison of total hip arthroplasty via a posterior mini-incision versus a classic anterolateral approach]
    M Rittmeister
    Klinik für Orthopädie und Unfallchirurgie, Katharina Kasper gGmbH, St Marien Krankenhaus, Richard Wagner Strasse 14, 60318, Frankfurt M, Germany
    Orthopade 35:716, 718-22. 2006
    ..Surgical time, blood loss, risk of malpositioned implants, or complications were not increased for THA patients operated through minimally invasive posterior incisions compared to those operated via classic anterolateral approaches...
  65. ncbi Total hip arthroplasty: is small incision better?
    Michael Ciminiello
    Rothman Institute of Orthopedics at Thomas Jefferson University, Philadelphia, Pennsylvania 19107, USA
    J Arthroplasty 21:484-8. 2006
    ..We were not able to detect any difference in outcome parameters for THA performed through small incision compared with the conventional techniques...
  66. ncbi Robotic surgery in gynecology
    J F Magrina
    Director Division of Gynecologic Oncology Department of Gynecology, Division of Gynecologic Oncology, Mayo Clinic, Scottsdale, AZ 85259, USA
    Eur J Gynaecol Oncol 28:77-82. 2007
    ....
  67. ncbi Pediatric minimal-access surgery: update 2006
    Jeffrey L Zitsman
    Division of Pediatric Surgery, College of Physicians and Surgeons, Columbia University, New York, New York, USA
    Pediatrics 118:304-8. 2006
    ..Randomized, controlled studies have been difficult to perform because of parent, patient, and physician selection bias...
  68. ncbi Recent trends in minimally invasive cardiac surgery
    Alan P Kypson
    Division of Cardiothoracic Surgery, Brody School of Medicine, East Carolina University, Greenville, NC, USA
    Cardiology 107:147-58. 2007
    ..Evolving technologies have resulted in an increase in minimally invasive cardiac surgery. Currently, robotic systems allow surgeons to perform a variety of procedures through small incisions. This changing paradigm is reviewed...
  69. ncbi Role of minimally invasive surgery in gynecologic cancers
    Alan C Schlaerth
    Memorial Sloan Kettering Cancer Center, Gynecology Service, Department of Surgery, 1275 York Avenue, New York, New York 10021, USA
    Oncologist 11:895-901. 2006
    ..Extraperitoneal laparoscopy for para-aortic and pelvic lymph node dissections has been shown to yield adequate nodal counts and to be safe and feasible in the management of gynecologic cancers...
  70. ncbi Minimally invasive total hip arthroplasty: the posterior approach
    Thomas P Sculco
    Hospital for Special Surgery, New York, New York, USA
    Instr Course Lect 55:205-14. 2006
    ..Blood loss has been documented to be less and early recovery is facilitated. Compared with the standard posterior approach, there have been fewer complications associated with the modified approach...
  71. ncbi Open transthoracic or transhiatal esophagectomy versus minimally invasive esophagectomy in terms of morbidity, mortality and survival
    I Braghetto
    Department of Surgery, University Hospital, Faculty of Medicine, University of Chile, Santos Dumont 999, Santiago, Chile
    Surg Endosc 20:1681-6. 2006
    ..Surgical treatment of esophageal cancer is associated with a high rate of morbidity and mortality even in specialized centers. Minimally invasive surgery has been proposed to decrease these complications...
  72. ncbi Keyhole approach for posterior cervical discectomy: experience on 84 patients
    Y S Caglar
    Department of Neurosurgery, Ankara University, School of Medicine, Sihhiye, Ankara, Turkey
    Minim Invasive Neurosurg 50:7-11. 2007
    ..Microsurgery enables us to both preserve the motion of operated segment and avoid cervical instability...
  73. ncbi Posterior minimally invasive approaches for the cervical spine
    Vishal C Gala
    Section of Neurosurgery, University of Chicago, Chicago, IL 60637, USA
    Orthop Clin North Am 38:339-49; abstract v. 2007
    ..Complication avoidance and management is also discussed...
  74. ncbi Atraumatic restorative treatment and dental anxiety in outpatients attending public oral health clinics in South Africa
    Steffen Mickenautsch
    Division of Public Oral Health, University of the Witwatersrand, Johannesburg, South Africa
    J Public Health Dent 67:179-84. 2007
    ..This study was undertaken to test the hypotheses that using the atraumatic restorative treatment (ART) approach results in lower patient anxiety and that lower anxiety leads to higher restoration/extraction ratios...
  75. ncbi Minimally invasive total hip arthroplasty: a randomized controlled prospective trial
    Farhad Mazoochian
    Department of Orthopaedic Surgery, Grosshadern Medical Center, Ludwig Maximilian University, Marchioninistr 15, 81377, Munich, Germany
    Arch Orthop Trauma Surg 129:1633-9. 2009
    ..Advantages of minimally invasive total hip arthroplasty (THA) are controversially discussed...
  76. ncbi Percutaneous tumor curettage and interstitial delivery of samarium-153 coupled with kyphoplasty for treatment of vertebral metastases
    Erico R Cardoso
    Department of Surgery, New York Methodist Hospital and Weill Medical Center, Cornell University, Brooklyn, New York 11215, USA
    J Neurosurg Spine 10:336-42. 2009
    ....
  77. ncbi Robotically assisted laparoscopic transhiatal esophagectomy
    C A Galvani
    Minimally Invasive Surgery Center, University of Illinois, 840 South Wood Street, Room 435, Chicago, IL 60612, USA
    Surg Endosc 22:188-95. 2008
    ..The goal of this report is to describe the authors' early experience using robotically assisted technology to perform transhiatal esophagectomy (RATE)...
  78. ncbi Minimally invasive lumbar fusion
    Kevin T Foley
    Image Guided Surgery Research Center, Methodist Hospitals of Memphis, Semmes Murphey Clinic and the Department of Neurosurgery, University of Tennessee, Memphis 38104, USA
    Spine (Phila Pa 1976) 28:S26-35. 2003
    ..Review article...
  79. ncbi Minimally invasive versus standard approach in total knee arthroplasty
    Yasutaka Tashiro
    Department of Orthopaedic Surgery, Graduate School of Medical Sciences, Kyushu University, 3 1 1 Maidashi, Higashi ku, Fukuoka 812 8582, Japan
    Clin Orthop Relat Res 463:144-50. 2007
    ..We encountered no major perioperative complications in either group. We believe the minimally invasive technique positively contributes to the early restoration of quadriceps strength and a speedy return to normal function...
  80. pmc Less invasive Achilles tendon reconstruction
    Michael R Carmont
    Department of Trauma and Orthopaedics, University Hospital of North Staffordshire, Keele University School of Medicine, Stoke on Trent, ST7 4QG UK
    BMC Musculoskelet Disord 8:100. 2007
    ..Reconstruction of the Achilles tendon using peroneus brevis has been widely reported. Classically, these procedures involve relatively long surgical wounds in a relatively hypovascular area which is susceptible to wound breakdown...
  81. ncbi Initial trial of a stereoscopic, insertable, remotely controlled camera for minimal access surgery
    Dennis L Fowler
    College of Physicians and Surgeons, Department of Surgery, Columbia University, New York, NY 10023, USA
    Surg Endosc 24:9-15. 2010
    ....
  82. ncbi Twenty-gauge transconjunctival sutureless vitrectomy trocar system
    Anna Paula Lafetá
    AZ Sint Augustinus Hospital, Posterior Segment Department, Antwerpen, Belgium
    Retina 27:1136-41. 2007
  83. ncbi Innovative laparoscopic surgery in gynecologic oncology
    Siobhan M Kehoe
    Gynecology Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, 1275 York Avenue, New York, NY 10021, USA
    Curr Oncol Rep 9:472-7. 2007
    ..New techniques, including hand-assisted laparoscopic procedures and extraperitoneal lymph node dissections, are expanding the role of laparoscopy in the treatment of all gynecologic malignancies...
  84. ncbi The impact of minimally invasive surgical techniques on early range of motion after primary total knee arthroplasty
    Craig M McAllister
    Proliance Surgeons Inc, Evergreen Orthopedic Center, Kirkland, WA 98034, USA
    J Arthroplasty 23:10-8. 2008
    ..001). There was no significant difference in range of motion or functional outcome at 1 year after surgery. There was no significant difference in component position or complication rates...
  85. ncbi Minimally invasive surgical ablation of atrial fibrillation: the thoracoscopic box lesion approach
    J Crayton Pruitt
    Cardiac Surgical Associates MAZE Workgroup, Tampa Saint Petersburg, FL 33756, USA
    J Interv Card Electrophysiol 20:83-7. 2007
    ..Potentially, these patients are ideal candidates for a minimally invasive thoracoscopic approach for the surgical treatment of atrial fibrillation...
  86. pmc Simultaneous bilateral MIS-TKA results in faster functional recovery
    Ilkyu Han
    Department of Orthopaedic Surgery, Seoul National University College of Medicine, Seoul National University Hospital, 28 Yongon Dong, Chongno Gu, Seoul, 110 744, Korea
    Clin Orthop Relat Res 466:1449-53. 2008
    ..Minimally invasive TKA may benefit patients undergoing simultaneous bilateral procedures with faster functional recovery...
  87. ncbi Haptics in minimally invasive surgery--a review
    E P Westebring-van der Putten
    Department of Applied Ergonomics and Design, Faculty of Industrial Design Engineering, Delft University of Technology, The Netherlands
    Minim Invasive Ther Allied Technol 17:3-16. 2008
    ..Improvement of haptic perception through augmented haptic information feedback in MIS might be promising...
  88. ncbi A meta-analysis of minimally invasive versus traditional open vein harvest technique for coronary artery bypass graft surgery
    Sheraz R Markar
    Department of Cardiothoracic Surgery, Papworth Hospital, Papworth Everard, Cambridge, UK
    Interact Cardiovasc Thorac Surg 10:266-70. 2010
    ..However, further studies are required to look at long-term graft patency following minimally invasive vein harvest as this remains a major concern...
  89. ncbi Is minimally invasive esophagectomy indicated for cancer?
    Irfan Qureshi
    Expert Rev Anticancer Ther 8:1449-60. 2008
    ..This review summarizes the current status of the use of minimally invasive surgery in treating esophageal cancer and seeks to answer the question of whether MIE is indicated in the treatment of esophageal cancer...
  90. pmc Comparison of a new, minimally invasive strabismus surgery technique with the usual limbal approach for rectus muscle recession and plication
    B J Kushner
    Br J Ophthalmol 91:5. 2007
  91. ncbi The minimally invasive surgical suite enters the 21st century. A discussion of critical design elements
    D M Herron
    Division of Laparoscopic Surgery, Department of Surgery, Mount Sinai Medical Center, 1 Gustave L Levy Place, 1103, New York, NY 10029, USA
    Surg Endosc 15:415-22. 2001
    Most minimally invasive surgical procedures are now performed in operating rooms that were originally designed for traditional open surgery...
  92. ncbi Two-incision minimally invasive total hip arthroplasty: techniques and results to date
    Paul J Duwelius
    Oregon Health Sciences Center and St Vincent s Hospital and Medical Center, Portland, Oregon, USA
    Instr Course Lect 55:215-22. 2006
    ....
  93. ncbi Modified maze during endoscopic mitral valve surgery: the OLV Clinic experience
    Hugues Jeanmart
    Department of Cardiovascular and Thoracic Surgery, OLV Clinic, Aalst, Belgium
    Ann Thorac Surg 82:1765-9. 2006
    ..The aim of this study was to evaluate our practice with the association of the mini-maze procedure, done with the use of the Cardioblade pen, and minimally invasive mitral valve surgery...
  94. ncbi A new vacuum-assisted probe for minimally invasive radiofrequency ablation
    Stefano Bevilacqua
    Adult Cardiac Surgery Department, Heart Hospital G Pasquinucci, G Monasterio Foundation, National Research Council, Massa, Italy
    Ann Thorac Surg 88:1317-21. 2009
    ..We evaluated this new technology for epicardial ablation of atrial fibrillation in mitral valve patients through a right mini-thoracotomy...
  95. ncbi Worldwide trends in the surgical treatment of primary hyperparathyroidism in the era of minimally invasive parathyroidectomy
    Wendy R Sackett
    University of Sydney Endocrine Surgical Unit, Department of Surgery, Royal North Shore Hospital, St Leonards, New South Wales 2065, Sydney, Australia
    Arch Surg 137:1055-9. 2002
    ..Minimally invasive surgery for primary hyperparathyroidism has become an accepted part of endocrine surgical practice worldwide...
  96. ncbi First experience with robot-assisted thoracoscopic esophagolymphadenectomy for esophageal cancer
    R van Hillegersberg
    Department of Surgery, University Medical Center Utrecht, P O Box 85500, 3508, GA, Utrecht, The Netherlands
    Surg Endosc 20:1435-9. 2006
    ..This morbidity rate could be reduced by the use of minimally invasive techniques. The feasibility of robot-assisted thoracoscopic esophagectomy (RTE) with mediastinal lymphadenectomy was assessed prospectively...
  97. ncbi Minimally invasive cervical microendoscopic foraminotomy: an initial clinical experience
    Richard G Fessler
    Institute for Spine Care, Chicago Institute of Neurosurgery and Neuroresearch, Rush Presbyterian Medical Center, Chicago, Illinois 60637, USA
    Neurosurgery 51:S37-45. 2002
    ..We have previously reported the feasibility of using the microendoscopic foraminotomy (MEF) technique in a cadaveric study. We now report our initial clinical experience with this novel technique...
  98. ncbi Evaluation of structured and quantitative training methods for teaching intracorporeal knot tying
    A M Pearson
    Department of Surgery, Yale University School of Medicine, 40 Temple Street, Suite 3 A, New Haven, CT 06510, USA
    Surg Endosc 16:130-7. 2002
    ..We evaluated the effectiveness of five training methods-four structured and one unstructured-for teaching intracorporeal knot tying...
  99. ncbi Training the novice in laparoscopy. More challenge is better
    M R Ali
    Department of Surgery, Medical College of Virginia, 1200 East Broad Street, West Hospital, Floor 15, P O Box 980519, Richmond, VA 23298, USA
    Surg Endosc 16:1732-6. 2002
    ..Virtual reality simulation is effective in training the novice to perform basic laparoscopic skills...
  100. ncbi The Oxford medial unicompartmental knee replacement using a minimally-invasive approach
    H Pandit
    Department of Orthopaedic Surgery, Nuffield Orthopaedic Centre, Headington, Oxford OX3 7LD, UK
    J Bone Joint Surg Br 88:54-60. 2006
    ..This study demonstrates that the minimally-invasive Oxford unicompartmental knee replacement is a reliable and effective procedure...
  101. ncbi Comparison of extended esophagectomy through mini-thoracotomy/laparotomy with conventional thoracotomy/laparotomy for esophageal cancer
    Kosuke Narumiya
    Department of Surgery, Institute of Gastroenterology, Tokyo Women s Medical University, Tokyo, Japan
    Jpn J Thorac Cardiovasc Surg 53:413-9. 2005
    ..In order to assess the usefulness of esophagectomy through mini-thoracotomy/laparotomy as a minimally invasive surgical procedure for esophageal cancer, we compared the results to those of conventional right thoracotomy/laparotomy...

Research Grants56

  1. NONPHARMACOLOGIC ANALGESIA FOR INVASIVE PROCEDURES
    Elvira Lang; Fiscal Year: 2005
    Analgesics and sedatives administered to control distress from minimally invasive surgical procedures have limited effectiveness and serious side effects...
  2. Clinical Development of Hemostatic Agent ClotFoam for Severe Hemorrhage
    Maja Nowakowski; Fiscal Year: 2013
    ..Substantial economic activity will be generated from the global provision of this core component. ..
  3. Comparative Effectiveness of Novel Minimally Invasive Surgical Procedures
    Juliane Bingener-Casey; Fiscal Year: 2013
    ..outcome measures for the efficient, consistent, and well-validated comparison of novel minimally invasive surgical procedures with standard of care procedures...
  4. EVALUATION OF ENDOBRONCHIAL INTERVENTIONS FOR COPD VIA CT AND 3HE MRI
    Jason C Woods; Fiscal Year: 2011
    ....
  5. Data-driven Real-Time Surgical Simulation from Reality-based Soft-tissue Models
    JAYDEV DESAI; Fiscal Year: 2009
    ..Because of the loss of natural sense of touch and visual feedback in minimally invasive surgical procedures, there is a compelling need for haptics and real-time graphics based surgical simulators for ..
  6. ELECTRICAL IMPEDANCE TOMOGRAPHY IMAGED CRYOSURGERY
    Boris Rubinsky; Fiscal Year: 2003
    ..Completion of the project will establish EIT as effective for imaging minimally invasive surgical procedures in general and cryosurgery, in particular.
  7. Precision Freehand Sculptor
    Constantinos Nikou; Fiscal Year: 2004
    ..be made much smaller than the conventional robots, PFS could play an important role in supporting minimally invasive surgical procedures. Our initial focus will be on minimally invasive knee arthroplasty, in particular on Patello-..
  8. Magnetic Location System For Catheter Guidance
    Timothy Riehle; Fiscal Year: 2009
    Catheter localization is a key technology for advancing minimally invasive surgical procedures. Localization technology provides an alternative to imaging in many catheter procedures and is presently applied in several specialties ..
  9. Intervertebral disc repair with Mesenchymal Stem Cells
    Jeffrey Lotz; Fiscal Year: 2007
    ..Upon successful completion, we will extend this work to a large animal model of disc degeneration where surgical, biological, and mechanical challenges more closely match those anticipated with human use. [unreadable] [unreadable]..
  10. DISPOSABLE, MAGNETICALLY SUSPENDED BLOOD PUMP
    Hsiang Chen; Fiscal Year: 2000
    ..Additionally, it can be located on the OR table, with special catheter set, for minimally invasive surgical procedures.
  11. MINIMALLY-INVASIVE SURGICAL PLANNING AND TRAINING SYSTEM
    DAVID KYNOR; Fiscal Year: 2001
    ..Our commercialization strategy is based on licensing the technology developed under this program to an existing vendor of medical equipment. ..
  12. Angiogenesis and Cardiac Growth as Heart Failure Therapy
    Y Woo; Fiscal Year: 2008
    ..The candidate's institution, sponsor, and chairman provide a uniquely supportive, high-caliber, educationally stimulating environment highly conducive to the achievement of these goals. ..
  13. Regulation of Fibroblast Survival in the Collagen Matrix
    Mark Carlson; Fiscal Year: 2005
    ..Loss of matrix anchorage is hypothesized to reverse these effects and induce apoptosis. The involvement of each protein will be probed with mutated isoforms. ..
  14. Robotically Assisted Mouse Interventions
    Kevin Cleary; Fiscal Year: 2008
    ..3. Perform a feasibility study using 10 mice to demonstrate the ability of the robot to biopsy the mouse flank as selected on the MRI images and evaluate the accuracy of the system. [unreadable] [unreadable] [unreadable]..
  15. Haptic Feedback for Robot-Assisted Surgical Systems
    Allison Okamura; Fiscal Year: 2006
    ..abstract_text> ..
  16. Fish Oil Modulation of Tumor Inflammation
    NOCIF ESPAT; Fiscal Year: 2006
    ....
  17. Thermo mechanical stress in cryopreserved blood vessels
    Yoed Rabin; Fiscal Year: 2006
    ..Although the experimental work in this study is targeted to blood vessels, the results of this study could be expanded and become useful for a wide variety of cryopreserved natural tissues and engineered constructs. ..
  18. Developing computerized tools for cryosurgery planning
    Yoed Rabin; Fiscal Year: 2007
    ..Such visualization capabilities will provide surgeons with insights into the physics of cryosurgery that are difficult to obtain from physical experiments or surgical practice. [unreadable] [unreadable]..
  19. Phase II Clinical Trial Utilizing Lithium for Patients with Neuroendocrine Tumors
    Herbert Chen; Fiscal Year: 2008
    ..Besides surgery, there are limited curative and palliative treatments available to patients with metastatic NE tumors, emphasizing the need for development of other forms of therapy. [unreadable] [unreadable] [unreadable]..
  20. Homocysteine/Hypertension & Vascular Lesion Formation
    Peter Lin; Fiscal Year: 2008
    ..abstract_text> ..
  21. Photodynamic Therapy for the Treatment of Obstructive E*
    Todd Demmy; Fiscal Year: 2007
    ..This proposal will be instrumental in the development of a novel PDT drug without long-term restrictions of patients' sun exposure. [unreadable] [unreadable]..
  22. PROMOTING TRANSLATIONAL DENTAL RESEARCH ACADEMIC CAREERS
    EDWARD ROSSOMANDO; Fiscal Year: 2008
    ..Additionally, we intend to track attitudinal changes as the student's progress through the 4-year program, and monitor the student's career choices and progress after graduation from dental school. ..
  23. Quantitative Imaging with High Frequency Ultrasound
    Emad Ebbini; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  24. Regulating Neuroendocrine Phenotype in Cancer
    Herbert Chen; Fiscal Year: 2010
    ..Furthermore, these finding may permit development of components of raf-1 pathway as therapeutic targets in the treatment and palliation of NE tumors. ..
  25. Continued Development for The Image-guided Surgical Toolkit Project (IGSTK)
    Kevin Cleary; Fiscal Year: 2009
    ....
  26. Chitosan hemostatic device for laparoscopic applications
    Hua Xie; Fiscal Year: 2005
    ..abstract_text> ..
  27. Novel Signaling Targets in GI Neuroendocrine Tumors
    Herbert Chen; Fiscal Year: 2005
    ..The possibility that raf-l-mediated hormone suppression could be induced by a soluble factor would provide a plausible, therapeutic delivery method. ..
  28. The Effects of Resveratrol on Presbyacusis
    Michael Seidman; Fiscal Year: 2004
    ..Furthermore, these data will provide novel strategies to impart greater wellness in the elderly population and perhaps have a positive effect on health care expenses. ..
  29. Towards a Non-Invasive Therapy for Atrial Fibrillation
    Benjamin Scherlag; Fiscal Year: 2004
    ..This new therapeutic approach could be utilized as a non-invasive application or incorporated into an implantable device for treatment of patients with PAF. ..
  30. Signaling Pathways in Medullary Thyroid Cancer
    Herbert Chen; Fiscal Year: 2004
    ..abstract_text> ..
  31. Molecular response of bile duct cell to bile duct injury
    Ai Xuan Holterman; Fiscal Year: 2005
    ..Bile duct specific target gene mRNA and protein expression will be assessed and the effect on the development of biliary fibrosis will be determined. ..
  32. Biomechanical Modeling for Steerable Needles
    Allison Okamura; Fiscal Year: 2005
    ..A particular challenge is the development of new modeling techniques that simultaneously handle needle and tissue deformation. ..
  33. Peptides surface modification to prevent stent blockage
    Joseph Leung; Fiscal Year: 2006
    ..The results may shed new lights in the prevention of chronic implanted medical device related infections and specifically in prolonging plastic stent patency. [unreadable] [unreadable]..
  34. NON-INVASIVE SURROGATE MARKERS FOR DIABETIC NEUROPATHY
    Andrew Boulton; Fiscal Year: 2004
    ....
  35. OR2020 Workshop: Operating Room of the Future
    Kevin Cleary; Fiscal Year: 2004
    ..The workshop is currently scheduled to be held from April 16-17, 2004, at Turf Valley Conference Center in Ellicot City, Maryland. ..
  36. Workshop Course to Promote and Develop Dental Technology
    EDWARD ROSSOMANDO; Fiscal Year: 2004
    ..Upon completion of this project, it is anticipated that an extensively tested and refined program will be available and suitable to convey essential information needed to develop these competencies. ..
  37. CT fluoroscopy guided robotically assisted lung biopsy
    Kevin Cleary; Fiscal Year: 2005
    ..The system will be validated in phantom and animal studies. The R33 phase will result in a system that is ready for clinical trials. ..
  38. Software Toolkit for Image Guided Surgery
    Kevin Cleary; Fiscal Year: 2005
    ..Dissemination activities will be undertaken with the aim of fostering the use of the toolkit in research and clinical applications. ..
  39. Genetic and molecular characterization of kidney cancer
    Allan Pantuck; Fiscal Year: 2005
    ..abstract_text> ..
  40. Mechanisms of Axonal Sprouting After Stroke
    STANLEY CARMICHAEL; Fiscal Year: 2007
    ..These experiments will identify neuronal growth programs after stroke, and Iocal inhibitory molecules, and provide an understanding of the mechanisms of regeneration in the adult brain. ..
  41. Foxm1b and HNF-6 regulation of liver injury response
    Ai Xuan Holterman; Fiscal Year: 2006
    ..The potential of salvaging failed liver, improving the quality of life or extending survival of patients with liver insufficiency using these therapeutic strategies is far reaching. ..
  42. Development and Clinical Testing of CorAide RVAD/BVAD
    Kiyotaka Fukamachi; Fiscal Year: 2008
    ..The successful completion of this program will provide clinicians and patients with a safe and effective option for outpatient mechanical support that allows an excellent quality of life. ..
  43. Steering Flexible Needles in Soft Tissue
    ALLISON MARIKO OKAMURA; Fiscal Year: 2010
    ..steering, with the goals of improving current clinical applications and leading to new ultra-minimally invasive surgical procedures. The results of this project could significantly improve public health by lowering patient ..
  44. Mechanisms of Neuronal Regeneration after Stroke in a Novel Neurovascular Niche
    STANLEY THOMAS CARMICHAEL; Fiscal Year: 2010
    ..An understanding of the molecules that promote this neural stem cell response after stroke will help develop novel therapies to promote replacement of brain cells in this disease. ..
  45. Randomized trial of doxorubicin beads for arterial embolization of hepatocellular
    Karen Brown; Fiscal Year: 2008
    ..This study is designed to determine the incremental value of arterial chemotherapy, as well as to validate an automated imaging method of assessing response to treatment. [unreadable] [unreadable] [unreadable]..
  46. The Prevalence of Barrett's Esophagus in Patients with *
    Blair Jobe; Fiscal Year: 2004
    ..In addition, this study will enhance our understanding of the natural history of esophageal injury in patients with extraesophageal reflux and raise awareness of non-GERD risk factors. ..
  47. Mitral Annular Remodeling for MR Therapy
    Kiyotaka Fukamachi; Fiscal Year: 2005
    ..Therefore, this proposed research program is an important first step in this novel procedure's development as one potential therapeutic option for high-risk CHF patients with functional MR. ..
  48. Randomized Trial of EUS Neurolysis in Pancreas Cancer
    Michael Wallace; Fiscal Year: 2006
    ..The primary outcome will be a reduction in pain at 1 month. Secondary outcomes will include the durability of pain control, quality of life, narcotic use and narcotic side effects. [unreadable] [unreadable]..
  49. Dectection of occult mediastinal lymph node mestastases
    Michael Wallace; Fiscal Year: 2007
    ..In the R33 component of the grant application these criteria will be prospectively evaluated and correlated with clinical outcome in a second, larger cohort of patients. ..
  50. A Unified Surgical Instrument System for Periodontal Minimally Invasive Surgery
    STEPHEN HARREL; Fiscal Year: 2007
    ..The resulting system, based on the surgical consultants evaluations and scores, will be used in a Phase 2 multicenter controlled clinical evaluation of MIS. [unreadable] [unreadable] [unreadable]..
  51. Targeting BCL-XL Expression in Mesothelioma
    W Smythe; Fiscal Year: 2006
    ..Upstream targets regulating bcl-xl expression for use in future therapeutic paradigms may be identified. ..
  52. Minimally Invasive Surgical Therapies for BPH - Treatme*
    Robert Donnell; Fiscal Year: 2005
    ..In summary, this proposal outlines what we believe to be the outstanding credentials of the Division of Urology, the Medical College of Wisconsin to serve as a clinical center in this multi-institutional trial. ..
  53. VIBRO-ACOUSTOGRAPHY SYSTEM WITH CONTACT ARRAY PROBE
    Mostafa Fatemi; Fiscal Year: 2005
    ....
  54. Liver Regeneration in Man--Effects or Adjuvant Therapy
    Yuman Fong; Fiscal Year: 2005
    ....
  55. CLINICAL AND BIOLOGICAL BASIS OF 18F-FDG PET IN CANCER
    Yuman Fong; Fiscal Year: 2001
    ..abstract_text> ..