microsurgery

Summary

Summary: The performance of surgical procedures with the aid of a microscope.

Top Publications

  1. ncbi A prospective randomized study with a 5-year minimum follow-up evaluation of transanal endoscopic microsurgery versus laparoscopic total mesorectal excision after neoadjuvant therapy
    G Lezoche
    Department of Surgery Paride Stefanini, II Clinica Chirurgica, University of Rome La Sapienza, Viale del Policlinico, 00161, Rome, Italy
    Surg Endosc 22:352-8. 2008
  2. ncbi Purely endoscopic transsphenoidal surgery versus traditional microsurgery for resection of pituitary adenomas: systematic review
    Julie Strychowsky
    Otolaryngology Head and Neck Surgery, McMaster University, 1200 Main St W, Hamilton, ON L8N 3Z5
    J Otolaryngol Head Neck Surg 40:175-85. 2011
  3. ncbi Forces for morphogenesis investigated with laser microsurgery and quantitative modeling
    M Shane Hutson
    Department of Physics and Free Electron Laser Laboratory, Duke University, Durham, NC 27708, USA
    Science 300:145-9. 2003
  4. ncbi Fully endoscopic transsphenoidal surgery for functioning pituitary adenomas: a retrospective comparison with traditional transsphenoidal microsurgery in the same institution
    Jean D'Haens
    Department of Neurosurgery, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, B 1090 Brussels, Belgium
    Surg Neurol 72:336-40. 2009
  5. ncbi Microsurgery plus whole brain irradiation versus Gamma Knife surgery alone for treatment of single metastases to the brain: a randomized controlled multicentre phase III trial
    Alexander Muacevic
    Department of Neurosurgery, Ludwig Maximilians University, Klinikum Grosshadern, Munich 81377, Germany
    J Neurooncol 87:299-307. 2008
  6. pmc Surgical treatment of male infertility in the era of intracytoplasmic sperm injection - new insights
    Sandro C Esteves
    Andrology and Human Reproduction Clinic, Sao Paulo, Brazil
    Clinics (Sao Paulo) 66:1463-78. 2011
  7. ncbi Transoral laser microsurgery as primary treatment for advanced-stage oropharyngeal cancer: a United States multicenter study
    Bruce H Haughey
    Department of Otolaryngology Head and Neck Surgery Washington University School of Medicine, St Louis, Missouri, USA
    Head Neck 33:1683-94. 2011
  8. ncbi Hypotony after 25-gauge vitrectomy
    Giulio Bamonte
    Department of Ophthalmology, Academic Medical Center, University of Amsterdam, The Netherlands
    Am J Ophthalmol 151:156-60. 2011
  9. pmc Swallowing function after transoral laser microsurgery (TLM) ± adjuvant therapy for advanced-stage oropharyngeal cancer
    Jason T Rich
    Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Laryngoscope 121:2381-90. 2011
  10. ncbi Long-term results after microsurgery for Cushing disease: experience with 426 primary operations over 35 years
    Bernd Markus Hofmann
    Department of Neurosurgery, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurosurg 108:9-18. 2008

Detail Information

Publications408 found, 100 shown here

  1. ncbi A prospective randomized study with a 5-year minimum follow-up evaluation of transanal endoscopic microsurgery versus laparoscopic total mesorectal excision after neoadjuvant therapy
    G Lezoche
    Department of Surgery Paride Stefanini, II Clinica Chirurgica, University of Rome La Sapienza, Viale del Policlinico, 00161, Rome, Italy
    Surg Endosc 22:352-8. 2008
    This study aimed to compare the oncologic results for local excision via transanal endoscopic microsurgery (TEM) and those for laparoscopic resection (LR) via total mesorectal excision in the treatment of T(2) N(0), G(1-2 )rectal cancer ..
  2. ncbi Purely endoscopic transsphenoidal surgery versus traditional microsurgery for resection of pituitary adenomas: systematic review
    Julie Strychowsky
    Otolaryngology Head and Neck Surgery, McMaster University, 1200 Main St W, Hamilton, ON L8N 3Z5
    J Otolaryngol Head Neck Surg 40:175-85. 2011
    ..To determine, in a systematic review, whether purely endoscopic transsphenoidal resection of pituitary adenomas offers improved outcomes and decreased complications compared to the traditional microscopic approach...
  3. ncbi Forces for morphogenesis investigated with laser microsurgery and quantitative modeling
    M Shane Hutson
    Department of Physics and Free Electron Laser Laboratory, Duke University, Durham, NC 27708, USA
    Science 300:145-9. 2003
    ....
  4. ncbi Fully endoscopic transsphenoidal surgery for functioning pituitary adenomas: a retrospective comparison with traditional transsphenoidal microsurgery in the same institution
    Jean D'Haens
    Department of Neurosurgery, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, B 1090 Brussels, Belgium
    Surg Neurol 72:336-40. 2009
    ..We report the endocrinologic outcome in 2 series of patients operated on at the same institution for functioning pituitary adenomas using these 2 different techniques...
  5. ncbi Microsurgery plus whole brain irradiation versus Gamma Knife surgery alone for treatment of single metastases to the brain: a randomized controlled multicentre phase III trial
    Alexander Muacevic
    Department of Neurosurgery, Ludwig Maximilians University, Klinikum Grosshadern, Munich 81377, Germany
    J Neurooncol 87:299-307. 2008
    ..Is Gamma Knife surgery alone as effective as surgery plus whole brain irradiation (WBRT) for patients with a single, small-sized brain metastasis?..
  6. pmc Surgical treatment of male infertility in the era of intracytoplasmic sperm injection - new insights
    Sandro C Esteves
    Andrology and Human Reproduction Clinic, Sao Paulo, Brazil
    Clinics (Sao Paulo) 66:1463-78. 2011
    ..infertile males, including the perioperative planning and prognostic aspects, with an emphasis on the role of microsurgery in the optimization of treatment results...
  7. ncbi Transoral laser microsurgery as primary treatment for advanced-stage oropharyngeal cancer: a United States multicenter study
    Bruce H Haughey
    Department of Otolaryngology Head and Neck Surgery Washington University School of Medicine, St Louis, Missouri, USA
    Head Neck 33:1683-94. 2011
    ..Oncologic and functional results have been modest. The aim of our study was to evaluate outcomes of a minimally invasive approach, using transoral laser microsurgery (TLM) as the primary treatment for advanced oropharyngeal carcinoma.
  8. ncbi Hypotony after 25-gauge vitrectomy
    Giulio Bamonte
    Department of Ophthalmology, Academic Medical Center, University of Amsterdam, The Netherlands
    Am J Ophthalmol 151:156-60. 2011
    ..To describe the incidence of hypotony after 25-gauge vitrectomy and to identify preoperative and intraoperative factors that influence the occurrence of hypotony...
  9. pmc Swallowing function after transoral laser microsurgery (TLM) ± adjuvant therapy for advanced-stage oropharyngeal cancer
    Jason T Rich
    Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Laryngoscope 121:2381-90. 2011
    To perform a longitudinal description of swallowing function following transoral laser microsurgery (TLM) ± adjuvant therapy for advanced-stage oropharyngeal cancer (OPC) and identify prognostic factors associated with swallowing ..
  10. ncbi Long-term results after microsurgery for Cushing disease: experience with 426 primary operations over 35 years
    Bernd Markus Hofmann
    Department of Neurosurgery, University of Erlangen Nuremberg, Erlangen, Germany
    J Neurosurg 108:9-18. 2008
    The aim of this paper was to demonstrate the long-term results following microsurgery in a single surgeon's continuous series of patients with Cushing disease (CD), to assess the influence of changes in surgical procedures, and to compare ..
  11. ncbi Transanal endoscopic microsurgery is more effective than traditional transanal excision for resection of rectal masses
    Jesse S Moore
    Department of Surgery, Fletcher Allen Health Care University of Vermont College of Medicine, Burlington, Vermont 05403, USA
    Dis Colon Rectum 51:1026-30; discussion 1030-1. 2008
    Transanal endoscopic microsurgery, developed by Buess in the 1980s, has become increasingly popular in recent years. No large studies have compared the effectiveness of transanal endoscopic microsurgery with traditional transanal excision.
  12. ncbi Pelviscrotal vasovasostomy: refining and troubleshooting
    Osama K Z Shaeer
    Department of Andrology, Faculty of Medicine, Cairo University, Cairo, Egypt
    J Urol 174:1935-7. 2005
    ..In this study we present the results of performing the procedure bilaterally at the same session as well as technique troubleshooting...
  13. ncbi Transoral laser microsurgery for squamous cell carcinoma of the base of the tongue
    Wolfgang Steiner
    Department of Otorhinolaryngology Head and Neck Surgery, University of Goettingen, Robert Koch Str 40, 37075 Goettingen, Germany
    Arch Otolaryngol Head Neck Surg 129:36-43. 2003
    To determine the role of transoral laser microsurgery for base of tongue squamous cell carcinoma.
  14. ncbi The benefit of neuronavigation for neurosurgery analyzed by its impact on glioblastoma surgery
    C R Wirtz
    Department of Neurosurgery, Ruprecht Karls Universitat Heidelberg, Germany
    Neurol Res 22:354-60. 2000
    ..4 vs. 11.1 months). Neuronavigation increases radicality in glioblastoma resection without prolonging operating time. Regarding the problem of brain shift, neuronavigation should be optimized by intraoperative real-time imaging...
  15. ncbi Transoral carbon dioxide laser microsurgery for recurrent glottic carcinoma after radiotherapy
    Wolfgang Steiner
    Department of Otorhinolaryngology, Universitäts HNO Klinik, Robert Koch Str 40, D 37075 Gottingen, Germany
    Head Neck 26:477-84. 2004
    Transoral laser microsurgery is successfully performed in the treatment of primary laryngeal carcinomas. Few publications deal with the application in patients with recurrent glottic carcinomas after radiation failure...
  16. ncbi Intraoperative varicocele anatomy: a microscopic study of the inguinal versus subinguinal approach
    Carin V Hopps
    Center for Male Reproductive Medicine and Microsurgery, Cornell Institute for Reproductive Medicine, The New York Weill Cornell Medical Center, New York 10021, USA
    J Urol 170:2366-70. 2003
    ....
  17. ncbi A retrospective analysis of 154 arterialized venous flaps for hand reconstruction: an 11-year experience
    Sang Hyun Woo
    Kim and Woo s Institute for Hand and Reconstructive Microsurgery, Daegu Gangnam Hospital, Daegu, Korea
    Plast Reconstr Surg 119:1823-38. 2007
    ..The purpose of this study was to present the authors' 11-year clinical experience involving 154 cases of arterialized venous flaps for hand reconstruction...
  18. ncbi Cancer-cell microsurgery using nonlinear optical endomicroscopy
    Min Gu
    Swinburne University of Technology, Centre for Micro Photonics, Faculty of Engineering and Industrial Sciences, Hawthorn, Victoria 3122, Australia
    J Biomed Opt 15:050502. 2010
    Near-infrared laser-based microsurgery is promising for noninvasive cancer treatment...
  19. ncbi Phacoemulsification versus manual small-incision cataract surgery for white cataract
    Rengaraj Venkatesh
    Aravind Eye Hospital, Pondicherry, India
    J Cataract Refract Surg 36:1849-54. 2010
    ..To compare the safety and efficacy of phacoemulsification and manual small-incision cataract surgery (SICS) to treat white cataracts in southern India...
  20. pmc A sub-millimetric, 0.25 mN resolution fully integrated fiber-optic force-sensing tool for retinal microsurgery
    Iulian Iordachita
    Johns Hopkins University, CSEB 112, Baltimore, MD 21218, USA
    Int J Comput Assist Radiol Surg 4:383-90. 2009
    Retinal microsurgery requires extremely delicate manipulation of retinal tissue where tool-to-tissue interaction forces are usually below the threshold of human perception...
  21. pmc Combining laser microsurgery and finite element modeling to assess cell-level epithelial mechanics
    M Shane Hutson
    Department of Physics and Astronomy, Vanderbilt University, Nashville, Tennessee, USA
    Biophys J 97:3075-85. 2009
    Laser microsurgery and finite element modeling are used to determine the cell-level mechanics of the amnioserosa-a morphogenetically crucial epithelium on the dorsal surface of fruit fly embryos (Drosophila melanogaster)...
  22. ncbi Conventional versus microdissection testicular sperm extraction for nonobstructive azoospermia
    Hiroshi Okada
    Division of Urology, Department of Organ Therapeutics, Faculty of Medicine, Kobe University Graduate School of Medicine, Kobe, Japan
    J Urol 168:1063-7. 2002
    ..We established a practical and safe strategy for testicular sperm extraction (TESE) in patients with nonobstructive azoospermia and compared conventional with microdissection TESE...
  23. ncbi Impact of reconstructive microsurgery in patients with advanced oral cavity cancers
    Matthew M Hanasono
    Department of Plastic Surgery, University of Texas, M D Anderson Cancer Center, Houston, Texas, USA
    Head Neck 31:1289-96. 2009
    Our goal was to determine the impact of reconstructive microsurgery on the treatment of advanced oral cavity cancers.
  24. ncbi Efficacy of varicocelectomy in improving semen parameters: new meta-analytical approach
    Ashok Agarwal
    Reproductive Research Center, Glickman Urological Institute, Department of Obstetrics Gynecology, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Urology 70:532-8. 2007
    ..To determine the efficacy of varicocelectomy in improving semen parameters...
  25. ncbi Outcome of transoral laser microsurgery for T2-T3 tumors growing in the laryngeal anterior commissure
    Jose Luis Blanch
    ENT Surgical Oncology Section, Hospital Clinic, Barcelona, Spain
    Head Neck 33:1252-9. 2011
    To evaluate the outcomes of transoral laser microsurgery (TLM) in the treatment of T2 to T3 laryngeal carcinomas growing in the laryngeal anterior commissure.
  26. ncbi Neovascularization and free microsurgical transfer of in vitro cartilage-engineered constructs
    Nguyen The Hoang
    Department of Hand Surgery and Microsurgery, Institute of Trauma and Orthopedics, Central University Hospital, Hanoi, Vietnam
    Microsurgery 29:52-61. 2009
    ..removed based on the newly implanted vascular pedicle, and then freely retransferred into position using microsurgery. Macroscopic observation, selective microangiography, histology, and immunohistochemistry were performed to ..
  27. ncbi Endoscopic versus microscopic trans-sphenoidal pituitary surgery: a systematic review and meta-analysis
    J K Goudakos
    1st Department of Otorhinolaryngology Head and Neck Surgery, AHEPA University Hospital, Aristotle University of Thessaloniki, Greece
    Clin Otolaryngol 36:212-20. 2011
    ..Endoscopic trans-sphenoidal surgery has been increasingly replacing microscopic surgery as the state of the art trans-sphenoidal approach...
  28. pmc Investigation of reperfusion injury and ischemic preconditioning in microsurgery
    Wei Zhong Wang
    Department of Surgery, Division of Plastic Surgery, University of Nevada School of Medicine, Las Vegas, NV 89102, USA
    Microsurgery 29:72-9. 2009
    ..One of the common complications after microsurgery is I/R-induced tissue death or I/R injury...
  29. ncbi High-accuracy patient-to-image registration for the facilitation of image-guided robotic microsurgery on the head
    Nicolas Gerber
    ARTORG Center for Biomedical Engineering Research, University of Bern, 3012 Bern, Switzerland
    IEEE Trans Biomed Eng 60:960-8. 2013
    Image-guided microsurgery requires accuracies an order of magnitude higher than today's navigation systems provide...
  30. ncbi Evaluation of wound closure using different incision techniques with 23-gauge and 25-gauge microincision vitrectomy systems
    Rishi P Singh
    Cole Eye Institute, Cleveland Clinic Foundation, OH 44195, USA
    Retina 28:242-8. 2008
    ..To describe the anatomic and histopathologic outcomes using different incision techniques with transconjunctival 23-G and 25-G vitrectomy systems...
  31. pmc Laser microsurgery in Caenorhabditis elegans
    Christopher Fang-Yen
    Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA
    Methods Cell Biol 107:177-206. 2012
    ..Here, we review the implementation and application of currently used methods for target edoptical disruption in C. elegans...
  32. ncbi Comparison of endoscopic and microscopic removal of pituitary adenomas: single-surgeon experience and the learning curve
    BERT W O'MALLEY
    Departments of Otorhinolaryngology, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania, USA
    Neurosurg Focus 25:E10. 2008
    ..They also attempted to determine the learning curve associated with a surgical team converting to endoscopic techniques...
  33. ncbi NOTES rectosigmoid resection using transanal endoscopic microsurgery (TEM) with transgastric endoscopic assistance: a pilot study in swine
    Patricia Sylla
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    J Gastrointest Surg 12:1717-23. 2008
    Transanal endoscopic microsurgery (TEM) provides direct endoscopic access to the rectum and peritoneal cavity...
  34. ncbi Treatment of palpable varicocele in infertile men: a meta-analysis to define the best technique
    Selahittin Cayan
    University of Mersin School of Medicine, Department of Urology, 33079 Mersin, Turkey
    J Androl 30:33-40. 2009
    ..However, prospective, randomized, and comparative studies with large number of patients are needed to compare the efficacy of microsurgical varicocelectomy with that of other treatment modalities in infertile men with varicocele...
  35. ncbi Transanal endoscopic microsurgical resection of pT1 rectal tumors
    Nadine Duhan Floyd
    Section of Colon and Rectal Surgery, Department of General Surgery, Rush University Medical Center, Chicago, Illinois 60612, USA
    Dis Colon Rectum 49:164-8. 2006
    Transanal endoscopic microsurgery has emerged as an improved method of transanal excision of neoplasms because its enhanced visibility, superior optics, and longer reach permit a more complete excision and precise closure...
  36. ncbi Mechanisms of laser cellular microsurgery
    Pedro A Quinto-Su
    Department of Chemical Engineering and Materials Science, University of California, Irvine, California 92697, USA
    Methods Cell Biol 82:113-51. 2007
    ..We relate this understanding of damage mechanisms to laser microbeam applications reported in the literature...
  37. ncbi Analysis of the cause of failure in nonsurgical endodontic treatment by microscopic inspection during endodontic microsurgery
    Minju Song
    Microscope Center, Department of Conservative Dentistry, College of Dentistry, Yonsei University, Seoul, Korea
    J Endod 37:1516-9. 2011
    This study examined the clinical causes of failure and the limitation of a previous endodontic treatment by an inspection of the root apex and resected root surface at 26× magnification during endodontic microsurgery.
  38. ncbi Comparison of outcomes of different varicocelectomy techniques: open inguinal, laparoscopic, and subinguinal microscopic varicocelectomy: a randomized clinical trial
    Ahmed M Al-Kandari
    Adan Urology Unit, Ministry of Health, Kuwait City, Kuwait
    Urology 69:417-20. 2007
    ..To compare the outcomes of the different surgical techniques used in varicocelectomy...
  39. ncbi The current role of microsurgery for posterior circulation aneurysms: a selective approach in the endovascular era
    Nader Sanai
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA
    Neurosurgery 62:1236-49; discussion 1249-53. 2008
    During the past decade, management of posterior circulation aneurysms has shifted away from microsurgery. Currently, microsurgical clipping is considered a primary, competitive alternative to endovascular coiling, or more commonly, a ..
  40. ncbi A new, validated instrument to evaluate competency in microsurgery: the University of Western Ontario Microsurgical Skills Acquisition/Assessment instrument [outcomes article]
    Claire L F Temple
    St Joseph s Health Care and the Division of Plastic Surgery, Department of Surgery, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Plast Reconstr Surg 127:215-22. 2011
    The authors present a model for microsurgery learning as well as a validated instrument to evaluate microsurgical competency.
  41. ncbi Validation of microsurgical models in microsurgery training and competence: a review
    Woan Yi Chan
    Department of Plastic Surgery, Pinderfields General Hospital, Aberford Road, Wakefield WF1 4DG, UK
    Microsurgery 27:494-9. 2007
    b>Microsurgery has expanded the scope of many surgical specialties and is evolving into an integral part of training programmes. The complexity of microsurgery requires considerable time and resources for adequate training and practice...
  42. pmc A microcosting study of microsurgery, LINAC radiosurgery, and gamma knife radiosurgery in meningioma patients
    Siok Swan Tan
    Erasmus Universiteit Rotterdam, Institute for Medical Technology Assessment, PO Box 1738, 3000 DR Rotterdam, The Netherlands
    J Neurooncol 101:237-45. 2011
    The aim of the present study is to determine and compare initial treatment costs of microsurgery, linear accelerator (LINAC) radiosurgery, and gamma knife radiosurgery in meningioma patients...
  43. ncbi Structured assessment of microsurgery skills in the clinical setting
    WoanYi Chan
    St Andrew s Centre for Plastic Surgery and Burns, Broomfield Hospital, Chelmsford, Essex, UK
    J Plast Reconstr Aesthet Surg 63:1329-34. 2010
    b>Microsurgery is an essential component in plastic surgery training. Competence has become an important issue in current surgical practice and training...
  44. ncbi Multimodality treatment of brain arteriovenous malformations with microsurgery after embolization with onyx: single-center experience and technical nuances
    Sabareesh K Natarajan
    Department of Neurological Surgery, University of Washington, Seattle, Washington, USA
    Neurosurgery 62:1213-25; discussion 1225-6. 2008
    ..To report our experience with the treatment of brain arteriovenous malformations (AVM) with microsurgical resection after embolization with Onyx liquid embolic agent (eV3, Irvine, CA)...
  45. ncbi Transanal endoscopic microsurgery: indications, results and controversies
    Andre Roncon Dias
    Department of Gastroenterology, Division of Colorectal Surgery, Hospital das Clinicas, University of Sao Paulo, Sao Paulo, Brazil
    Tech Coloproctol 13:105-11. 2009
    Transanal endoscopic microsurgery (TEM) was introduced in 1983 as a minimally invasive technique allowing the resection of adenomas and early rectal carcinomas unsuitable for local or colonoscopic excision which would otherwise require ..
  46. ncbi Beneficial effect of microsurgical varicocelectomy is superior for men with bilateral versus unilateral repair
    Jamie Libman
    Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
    J Urol 176:2602-5; discussion 2605. 2006
    ..Little is known about the differential effect of bilateral, compared to unilateral varicocelectomy, on male fertility potential...
  47. ncbi A prospective study about functional and anatomic consequences of transanal endoscopic microsurgery
    J A Gracia Solanas
    Section of Coloproctology, Department of Surgery B Hospital Clínico Universitario, Zargoza, Spain
    Rev Esp Enferm Dig 98:234-40. 2006
    transanal endoscopic microsurgery (TEM) was developed in 1983 by Büess as a minimally invasive technique to manage rectal villous adenomas and early rectal adenocarcinomas...
  48. ncbi Transoral laser microsurgery for untreated glottic carcinoma
    David G Grant
    Department of Otolaryngology Head and Neck Surgery, Mayo Clinic, Jacksonville, Florida 32224, USA
    Otolaryngol Head Neck Surg 137:482-6. 2007
    To report the oncology and functional outcomes of transoral laser microsurgery (TLM) for untreated glottic carcinoma.
  49. ncbi Microsurgical varicocelectomy for recurrent or persistent varicoceles associated with orchalgia
    Ashis Chawla
    Division of Urology, Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada
    Urology 66:1072-4. 2005
    ..To assess the effectiveness of microsurgical varicocelectomy for the treatment of recurrent varicoceles associated with orchalgia...
  50. ncbi Transoral laser microsurgery for carcinoma of the supraglottic larynx
    David G Grant
    Department of Otolaryngology Head and Neck Surgery, Mayo Clinic, Jacksonville, FL 32224, USA
    Otolaryngol Head Neck Surg 136:900-6. 2007
    The study goal was to report the oncologic outcomes of transoral laser microsurgery (TLM) in the treatment of squamous cell carcinoma of the supraglottic larynx.
  51. ncbi A decision analysis of treatments for obstructive azoospermia
    R Lee
    James Buchanan Brady Foundation, Department of Urology, Weill Medical College of Cornell University, 525 E 68th St, Starr 900, New York, NY 10021, USA
    Hum Reprod 23:2043-9. 2008
    ..We examined the cost-effectiveness of these treatments...
  52. ncbi Is the increasing role of Transanal Endoscopic Microsurgery in curation for T1 rectal cancer justified? A systematic review
    Pascal G Doornebosch
    Department of Surgery, Leiden University Medical Center, Leiden, The Netherlands
    Acta Oncol 48:343-53. 2009
    ....
  53. pmc Transoral laser microsurgery (TLM) +/- adjuvant therapy for advanced stage oropharyngeal cancer: outcomes and prognostic factors
    Jason T Rich
    Department of Otolaryngology Head and Neck Surgery, Washington University School of Medicine, St Louis, Missouri, USA
    Laryngoscope 119:1709-19. 2009
    Document survival, prognostic variables, and functional outcomes of patients with AJCC stage III or IV oropharyngeal cancer, treated with transoral laser microsurgery (TLM) +/- adjuvant therapy.
  54. ncbi NOTES transanal rectal cancer resection using transanal endoscopic microsurgery and laparoscopic assistance
    Patricia Sylla
    Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Surg Endosc 24:1205-10. 2010
    ..Translumenal Endoscopic Surgery (NOTES) transanal endoscopic rectosigmoid resection using transanal endoscopic microsurgery (TEM) was previously demonstrated in human cadavers and a porcine survival model...
  55. ncbi Retrorectal tumors: excision by transanal endoscopic microsurgery
    S Zoller
    Department of Surgery, University Hospital Mannheim, Germany
    Rev Esp Enferm Dig 99:547-50. 2007
    ..In order to achieve a complete excision of the tumor while minimizing trauma, transanal endoscopic microsurgery (TEM) was performed. The histology of the multicystic tumor revealed in all three cases a tailgut cyst...
  56. ncbi Conservative laser microsurgery for T1 glottic carcinoma
    M Manola
    Maxillo Facial and ENT Department, G Pascale National Institute of Tumors, Naples, Italy
    Auris Nasus Larynx 35:141-7. 2008
    ..We also studied surgical margins and the involvement of anterior commissure...
  57. ncbi Organ preserving transoral laser microsurgery for cancer of the hypopharynx
    Alexios Martin
    Department of Otorhinolaryngology Head and Neck Surgery, University of Gottingen, Gottingen, Germany
    Laryngoscope 118:398-402. 2008
    To assess the feasibility of transoral laser microsurgery (TLM) in the treatment of hypopharyngeal cancer, with a special focus on piriform sinus carcinomas, and to report the oncologic and functional outcomes.
  58. ncbi Beneficial effect of microsurgical varicocelectomy on human sperm DNA integrity
    A Zini
    Division of Urology, Department of Surgery, St Mary s Hospital, McGill University, 3830 Lacombe Avenue, Montreal, Quebec, H3T 1M5
    Hum Reprod 20:1018-21. 2005
    ..The objective of this study was to examine the effect of varicocelectomy on sperm DNA denaturation (DD, an index of sperm DNA damage) in infertile men with a clinical varicocele...
  59. ncbi Prospective clinical study evaluating endodontic microsurgery outcomes for cases with lesions of endodontic origin compared with cases with lesions of combined periodontal-endodontic origin
    Euiseong Kim
    Department of Conservative Dentistry, Department of Oral Biology and Oral Science Research Center, College of Dentistry, Yonsei University, Seoul, South Korea
    J Endod 34:546-51. 2008
    The aim of this study was to evaluate the outcomes of endodontic microsurgery by comparing the healing success of cases having a lesion of endodontic origin compared with cases having a lesion of combined endodontic-periodontal origin...
  60. ncbi Repair of primary rhegmatogenous retinal detachment using 25-gauge transconjunctival sutureless vitrectomy
    Michael M Lai
    Associated Retinal Consultants, William Beaumont Hospital, Royal Oak, Michigan, USA
    Retina 28:729-34. 2008
    ..To evaluate the anatomical and visual outcomes of primary rhegmatogenous retinal detachment repairs performed using 25-gauge transconjunctival sutureless vitrectomy...
  61. ncbi Postoperative medical complications--not microsurgical complications--negatively influence the morbidity, mortality, and true costs after microsurgical reconstruction for head and neck cancer
    Neil F Jones
    Division of Plastic and Reconstructive Surgery, University of California Los Angeles School of Medicine, Los Angeles, CA, USA
    Plast Reconstr Surg 119:2053-60. 2007
    ..There remains, however, ongoing debate on whether the costs associated with this reconstructive approach merit its selection, especially considering poor patient prognoses and the high cost of care...
  62. ncbi Transanal endoscopic microsurgery and radical surgery for T1 and T2 rectal cancer
    W Lee
    Department of Surgery, Gastrointestinal Center, Samsung Medical Center, Sungkyunkwan University, School of Medicine, 50, IlWon Dong, Kangnam Ku, Seoul, Korea
    Surg Endosc 17:1283-7. 2003
    Transanal endoscopic microsurgery (TEM) has gained increasing acceptance as a local treatment of early rectal cancer. The purpose of this study was to compare the results of TEM and radical surgery in patients with T1 and T2 rectal cancer.
  63. ncbi Indocyanine-green fluorescence video angiography used clinically to evaluate tissue perfusion in microsurgery
    Henning Mothes
    Department of Traumatology, University Hospital Jena, Germany
    J Trauma 57:1018-24. 2004
    ..angiography with indocyanine-green (ICG-FA) is a new diagnostic approach that allows quantitative evaluation of tissue perfusion in microsurgery as well as an analysis of the uptake, distribution, and clearance of dye-marked blood.
  64. ncbi Impact of neuronavigation and image-guided extensive resection for adult patients with supratentorial malignant astrocytomas: a single-institution retrospective study
    M Kurimoto
    Department of Neurosurgery, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930 0194, Japan
    Minim Invasive Neurosurg 47:278-83. 2004
    ..Our results showed that neuronavigation increases the radicality in the resection of malignant astrocytomas and is objectively useful for improving survival time...
  65. ncbi Transoral laser microsurgery for advanced laryngeal cancer
    Michael L Hinni
    Department of Otolaryngology, Head and Neck Surgery, Mayo Clinic Arizona, Phoenix, AZ 85054, USA
    Arch Otolaryngol Head Neck Surg 133:1198-204. 2007
    To report the oncologic and functional outcomes of transoral laser microsurgery (TLM) in the treatment of advanced laryngeal cancer.
  66. ncbi Prospective analysis of outcomes after microsurgical intussusception vasoepididymostomy
    Peter T K Chan
    Department of Urology, McGill University, Montreal, Quebec, Canada
    BJU Int 96:598-601. 2005
    To prospectively analyse the outcomes of microsurgical vasoepididymostomy using the intussusception technique, as vasoepididymostomy is considered the most challenging reconstructive microsurgery in urology.
  67. ncbi Outcome and late failures compared in 4 techniques of microsurgical vasoepididymostomy in 153 consecutive men
    Jonathan Schiff
    Department of Urology, Cornell Institute for Reproductive Medicine, Weill Medical College of Cornell University, The New York, New York 10021, USA
    J Urol 174:651-5; quiz 801. 2005
    Vasoepididymostomy remains one of the most technically challenging procedures in all of microsurgery. The technique has evolved from an end-to-end, to an end-to-side technique, then to intussusception end-to-side methods...
  68. ncbi Pituitary adenomas treated by microsurgery with or without Gamma Knife surgery: experience in 122 cases
    H K Inoue
    Department of Neurosurgery, Gunma University School of Medicine and Gamma Knife Center, Hidaka Hospital, Gunma, Japan
    Stereotact Funct Neurosurg 72:125-31. 1999
    The clinical outcome of 122 patients with pituitary adenomas treated by microsurgery and/or Gamma Knife radiosurgery (GKRS) was analyzed to evaluate patient selection criteria and the role of GKRS...
  69. ncbi Impact of anterior commissure involvement on local control of early glottic carcinoma treated by laser microresection
    Wolfgang Steiner
    Department of Otorhinolaryngology, University of Gottingen, Gottingen, Germany
    Laryngoscope 114:1485-91. 2004
    ..To analyze the impact of anterior commissure involvement on local control, survival, and laryngeal preservation in patients with early glottic cancer (pT1a-pT2a) treated with unimodality laser microsurgical resection...
  70. ncbi Superior outcomes of microsurgical vasectomy reversal in men with the same female partners
    Peter T K Chan
    Cornell Institute for Reproductive Medicine, Center for Male Reproductive Medicine and Microsurgery, New York, New York, USA
    Fertil Steril 81:1371-4. 2004
    ..To evaluate the outcomes of vasectomy reversals in men with the same female partners...
  71. ncbi Transsphenoidal microsurgery for newly diagnosed acromegaly: a personal view after more than 1,000 operations
    Dieter K Ludecke
    Department of Neurosurgery, Section of Pituitary Surgery, University Clinic of Hamburg, Hamburg, Germany
    Neuroendocrinology 83:230-9. 2006
    The aim of this short review is to inform about the possibilities and limits of transnasal microsurgery in acromegaly...
  72. ncbi Prospective multiple outcomes study of outpatient lumbar microdiscectomy: should 75 to 80% success rates be the norm?
    Harold L Asch
    Buffalo Neurosurgery Group, New York 14224, USA
    J Neurosurg 96:34-44. 2002
    ..The authors use the methodology and data derived from their study to evaluate critically the relevance of these two categories of success rates...
  73. ncbi Intraoperative magnetic resonance imaging to determine the extent of resection of pituitary macroadenomas during transsphenoidal microsurgery
    R J Bohinski
    Department of Neurosurgery, The Neuroscience Institute, University of Cincinnati College of Medicine, 231 Albert Sabin Way, Cincinnati, Ohio 45267-0515, USA
    Neurosurgery 49:1133-43; discussion 1143-4. 2001
    ..The surgeon is frequently surprised by the extent of residual tumor after an initial resection attempt and finds the intraoperative images useful for guiding further resection...
  74. ncbi Transanal single port microsurgery (TSPM) as a modified technique of transanal endoscopic microsurgery (TEM)
    Cornelia Lorenz
    Department of General and Visceral Surgery and Minimal Invasive Surgery, Luth Amalie Sieveking Hospital, Hamburg, Germany
    Surg Innov 17:160-3. 2010
    Single port access (SPA) surgery is a new procedure for minimal invasive surgery using one multichannel port. The authors adapted this technique for transanal surgery as an improvement of the transanal endoscopic microsurgery (TEM).
  75. ncbi Automated high-throughput cell microsurgery on-chip
    Kwanghun Chung
    School of Chemical and Biomolecular Engineering, Georgia Institute of Technology, Atlanta, GA, USA
    Lab Chip 9:2764-6. 2009
    ..We demonstrate here a technique combining multiplexing microfluidic manipulation of Caenorhabditis elegans and software for image processing and automation, allowing for high-throughput cell ablations...
  76. ncbi Oropharyngeal cancer: a case for single modality treatment with transoral laser microsurgery
    David G Grant
    Department of Otolaryngology Head and Neck Surgery, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA
    Arch Otolaryngol Head Neck Surg 135:1225-30. 2009
    To demonstrate the role of transoral laser microsurgery (TLM) in the treatment of oropharyngeal cancer.
  77. ncbi Role of varicocelectomy in men with nonobstructive azoospermia
    Peter N Schlegel
    Department of Urology, New York Presbyterian Hospital Weill Medical College of Cornell University, New York, New York 10021, USA
    Fertil Steril 81:1585-8. 2004
    ..To evaluate the benefits of varicocelectomy in men with nonobstructive azoospermia...
  78. ncbi A 10-year follow-up of the outcome of lumbar microdiscectomy
    G F Findlay
    Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
    Spine (Phila Pa 1976) 23:1168-71. 1998
    ..Patient satisfaction with the results of microdiscectomy 10 years later was high. CONCLUSIONS: Lumbar microdiscectomy achieves a high level of initial success, and this positive outcome is maintained at a 10-year follow-up...
  79. ncbi Transoral laser microsurgery for T3 laryngeal tumors: Prognostic factors
    Isabel Vilaseca
    Department of Oto Rhino Laryngology, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Head Neck 32:929-38. 2010
    The objective of this study was to evaluate the outcomes of transoral laser microsurgery (TLM) in T3 laryngeal carcinomas and to identify prognostic factors for survival and laryngeal preservation.
  80. ncbi Microsurgical excision of symptomatic sacral perineurial cysts: a study of 15 cases
    Wolfhard Caspar
    Department of Neurosurgery, Faculty of Medicine, Saarland University, Homburg Saar, Germany
    Surg Neurol 59:101-5; discussion 105-6. 2003
    ..In this retrospective study the efficacy of microsurgical cyst resection with duraplasty is evaluated...
  81. ncbi Use of 25-gauge vitrectomy in the management of primary rhegmatogenous retinal detachment
    Marco Mura
    Department of Ophthalmology, University of Amsterdam, The Netherlands
    Retina 29:1299-1304. 2009
    ..To evaluate the anatomical and functional results of 25-gauge transconjuctival vitrectomy in the management of primary rhegmatogenous retinal detachment (RRD)...
  82. ncbi Microsurgical treatment of symptomatic sacral perineurial cysts
    Dongsheng Guo
    Department of Neurosurgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
    Neurosurgery 60:1059-65; discussion 1065-6. 2007
    ..The aim of this study was to investigate the microsurgical results of symptomatic sacral perineurial cysts of 11 patients and to discuss the treatment options of the past 10 years...
  83. ncbi The role of laser microsurgery in the treatment of laryngeal cancer
    Petra Ambrosch
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Kiel, Germany
    Curr Opin Otolaryngol Head Neck Surg 15:82-8. 2007
    Transoral laser microsurgery has developed in recent years into a surgical method that combines a minimally invasive approach with the surgical precision of laser and microscope...
  84. ncbi The endoscopic versus the traditional approach in pituitary surgery
    Giorgio Frank
    Center of Surgery for Pituitary Tumors, Department of Neuroscience, Bellaria Hospital, Bologna, Italy
    Neuroendocrinology 83:240-8. 2006
    ....
  85. ncbi Treatment of recurrence after transanal endoscopic microsurgery (TEM) for T1 rectal cancer
    Pascal G Doornebosch
    Department of Surgery, IJsselland Hospital, Capelle a d Ijssel, The Netherlands
    Dis Colon Rectum 53:1234-9. 2010
    The aim of this study was to evaluate the management and outcome of local recurrences after transanal endoscopic microsurgery for T1 rectal cancer.
  86. pmc Digital holographic microscopy for quantitative cell dynamic evaluation during laser microsurgery
    Lingfeng Yu
    Beckman Laser Institute, University of California, Irvine, Irvine, CA 92617, USA
    Opt Express 17:12031-8. 2009
    ..Here, we report a quantitative phase laser microsurgery system for evaluation of cellular/ sub-cellular dynamic changes during laser micro-dissection...
  87. ncbi Long-term follow-up of cases considered healed one year after apical microsurgery
    Richard A Rubinstein
    Department of Endodontics, School of Dental Medicine, University of Pennsylvania, Philadelphia, USA
    J Endod 28:378-83. 2002
    ..Criteria for determining healed cases were the same as those used in the first report. Of the 59 roots evaluated, 54 (91.5%) remained healed, whereas 5 (8.5%) showed evidence of apical deterioration...
  88. ncbi Microsurgical vasoepididymostomy for obstructive azoospermia
    K L Ho
    Division of Urology, Department of Surgery, The University of Hong Kong, Queen Mary Hospital and Tung Wah Hospital, Hong Kong
    Hong Kong Med J 15:452-7. 2009
    ..To evaluate the efficacy of microsurgical vasoepididymostomy for patients with obstructive azoospermia attending our institutions...
  89. ncbi Basic microsurgery training: comments and proposal
    Paulo Ney Aguiar Martins
    Department of Surgery, Division of Transplant Surgery, Brigham and Women s Hospital, Harvard Medical School, 221 Longwood Avenue, Boston, MA 02115, USA
    Acta Cir Bras 22:79-81. 2007
    ..Here, we propose a model of a training course in microsurgery. We also suggest that surgical societies involved with microsurgery promote training courses on a regular basis.
  90. ncbi Impact of video-endoscopy on the results of retrosigmoid-transmeatal microsurgery of vestibular schwannoma: prospective study
    Martin Chovanec
    Department of Otorhinolaryngology, Head and Neck Surgery, 1st Faculty of Medicine, Faculty Hospital Motol, Charles University, V Uvalu 84, 150 06 Prague 5, Czech Republic
    Eur Arch Otorhinolaryngol 270:1277-84. 2013
    Endoscopy-assisted microsurgery represents modern trend of treatment of the cerebellopontine angle (CPA) pathologies including vestibular schwannoma (VS)...
  91. ncbi A predictive model for local recurrence after transanal endoscopic microsurgery for rectal cancer
    S P Bach
    Academic Department of Surgery, Queen Elizabeth Hospital, Birmingham, UK
    Br J Surg 96:280-90. 2009
    The outcome of local excision of early rectal cancer using transanal endoscopic microsurgery (TEM) lacks consensus. Screening has substantially increased the early diagnosis of tumours...
  92. ncbi Development of a training curriculum for microsurgery
    Indran Balasundaram
    Department of Biosurgery and Surgical Technology, Imperial College, London, United Kingdom
    Br J Oral Maxillofac Surg 48:598-606. 2010
    ..We review current publications about training and methods of assessment in microsurgery. Searches on PubMed using keywords (microsurgery, training, assessment, simulation, and skill) were used to ..
  93. ncbi Management and outcome of local recurrence following transanal endoscopic microsurgery for rectal cancer
    Francesco Stipa
    Colorectal Surgical Unit, Department of Surgery, S Giovanni Hospital, Rome, Italy
    Dis Colon Rectum 55:262-9. 2012
    Transanal endoscopic microsurgery is a faster and safer alternative to traditional surgical treatment of adenomas and low-risk (T1) rectal tumors...
  94. ncbi Guidelines for the optimization of microsurgery in atherosclerotic patients
    Hung Chi Chen
    Department of Plastic and Reconstructive Surgery, E Da Hospital I Shou University, Kaohsiung County, Taiwan, Republic of China
    Microsurgery 26:356-62. 2006
    ..review the pathogenesis of atherosclerosis and the issues that must be taken into consideration when performing microsurgery in atherosclerotic patients. Atherosclerosis is a systemic disease, and may affect the success of microsurgery...
  95. ncbi Treatment of laryngeal carcinomas by laser endoscopic microsurgery
    P R Moreau
    Department of Otorhinolaryngology and Audiophonology, University of Liege, Belgium
    Laryngoscope 110:1000-6. 2000
    To determine if laser endoscopic microsurgery is a reliable and appropriate approach in the treatment of laryngeal cancers.
  96. ncbi Surgical sperm recovery for intracytoplasmic sperm injection: which method is to be preferred?
    H Tournaye
    Centre for Reproductive Medicine, Dutch Speaking Brussels Free University, Belgium
    Hum Reprod 14:71-81. 1999
    ....
  97. ncbi Distant metastases after transoral laser microsurgery for laryngeal and hypopharyngeal squamous cell carcinoma
    Miguel Caballero
    Department of Otorhinolaryngology and Head and Neck Surgery, Hospital Clinic, University of Barcelona, Barcelona, Spain
    Head Neck 30:1599-606. 2008
    Transoral CO(2) laser microsurgery (TLM) resection of laryngeal-hypopharyngeal squamous cell carcinomas has become a standard procedure...
  98. ncbi Evaluation of a telerobotic system to assist surgeons in microsurgery
    H Das
    Jet Propulsion Laboratory, California Institute of Technology, Pasadena, California, USA
    Comput Aided Surg 4:15-25. 1999
    ..It will also enable performance of new surgical procedures that are beyond the capabilities of even the most skilled surgeons...
  99. ncbi [Clinical experience in using a metallic suture in eye microsurgery]
    Dushin N V Kumar Vinod
    Vestn Oftalmol 119:16-20. 2003
    The use of a metallic suture in eye microsurgery is described in the paper. The metallic suture made from a 0.05-0...
  100. ncbi Endoscopic trans-sphenoidal pituitary surgery: is it here to stay?
    M Powell
    Br J Neurosurg 21:315-7. 2007
  101. ncbi [Preventing lower limb amputations in patients suffering from diabetic foot syndrome and peripheral vascular disease - opportunities and limitations]
    S Schirmer
    Klinikum Bielefeld, Klinik für Plastische, Rekonstruktive und Ästhetische Chirurgie Handchirurgie, Bielefeld steff
    Handchir Mikrochir Plast Chir 43:338-44. 2011
    ..In one case a free instep flap of the contralateral foot, which had to be amputated, was used. In 13 cases the flap was anastomosed to the autologous bypass, in one case an AV loop was used...

Research Grants63

  1. Contribution of c-Jun N-terminal kinase activity to vestibular schwannoma growth
    Marlan R Hansen; Fiscal Year: 2013
    ..Further, some patients that require treatment are not good candidates for either microsurgery or SRS/SRT...
  2. Role of Transcription Factor ERG in Skeletogenesis
    Maurizio Pacifici; Fiscal Year: 2013
    ..The work will be carried out using diverse experimental approaches that include transgenic mouse genetics, microsurgery and cell phenotypic expression...
  3. Cellular Biomechanics of Heat-Shock Induced Defects in Drosophila Embryogenesis
    M Shane Hutson; Fiscal Year: 2013
    ..Methods to be used include time-lapse confocal imaging of GFP-labeled Drosophila embryos, laser-microsurgery to probe the biomechanics in vivo, laser-induced heat shocks of local regions within the embryos, and an ..
  4. HIGH-THROUGHPUT IN VIVO SUBCELLULAR-RESOLUTION VERTEBRATE SCREENING PLATFORM
    Mehmet Fatih Yanik; Fiscal Year: 2013
    ..The proposed high-speed whole-animal manipulation, orientation, immobilization, imaging, microsurgery, and injection platform will enable a dramatic increase in the throughput and complexity with which in vivo ..
  5. Chronic DTH and IFN-gamma in Human Graft Arteriosclerosis
    Jordan S Pober; Fiscal Year: 2010
    ..The Administrative Core (J.S. Pober, core leader) will administer the PPG. The Microsurgery Core (G...
  6. Satiety signaling in Caenorhabditis elegans
    Leon Avery; Fiscal Year: 2013
    ..TGF-2, and cGMP pathways by expression of transgenes from neuron-specific promoters in combination with laser microsurgery (hypotheses 2, 4, and 5)...
  7. RODENT PHENOTYPING CORE &OTHER TECHNICAL CORES
    RALPH VICTOR SHOHET; Fiscal Year: 2011
    ..by investigators who are usually more knowledgeable about molecular biology or biochemistry than physiology and microsurgery. The Mouse Phenotyping Core is designed to bring these techniques to investigators in the COBRE and wherever in ..
  8. Assessment of Reconstructive Surgical Flaps Using Spatially Resolved Tissue Oxima
    Anthony J Durkin; Fiscal Year: 2012
    ..Early in the era of microsurgery, flap monitoring was performed with only clinical observation of skin color, capillary refill, and dermal ..
  9. Lifespan regulation by the DAF-12 nuclear hormone receptor in C. elegans
    Cynthia J Kenyon; Fiscal Year: 2011
    ..During this funding period, the Kenyon lab will use genetics, laser microsurgery and molecular approaches to investigate how these and new genes act at the molecular level to execute and ..
  10. The Role of T cells and Macrophages in Cardiac Transplant Rejection
    Susan D Moffatt Bruce; Fiscal Year: 2010
    ..biology and protenomics core facilities, cell analysis and sorting core, laser capture microscopy and animal microsurgery suites...
  11. GENE EXPRESSION IN AMPHIBIAN DEVELOPMENT
    Richard M Harland; Fiscal Year: 2013
    ..the problem in the frog Xenopus, whose abundant eggs are large and readily manipulated by microinjection and microsurgery. The eggs are large enough to produce material for biochemical analysis, and importantly for this project, ..
  12. Harmonically detected swept source OCT
    Kristen A Peterson; Fiscal Year: 2011
    ..tissue including plaque deposits, guidance of biopsy needles to aid in cancer diagnosis, and guidance tools for microsurgery. The specific objective of this SBIR project is the development of a high speed, high resolution optical method ..
  13. In Vivo Analysis of the Mechanisms of Neural Crest Migration
    Paul Kulesa; Fiscal Year: 2012
    ..Using in vivo molecular perturbations and embryo microsurgery, together with photoactivation cell labeling, 4-D confocal imaging, cell tracking and cell behavior analyses, ..
  14. Ultra-Precise Laser Surgery to study Cell Biomechanics
    Yukiko Yamashita; Fiscal Year: 2013
    ..We will investigate the roles of cellular structure and geometry in regulating stem cell division using laser microsurgery tools and time-lapse live-imaging techniques developed in our group...
  15. FORMATION,INTERACTION & FUNCTION OF SPINDLE COMPONENTS
    Conly L Rieder; Fiscal Year: 2010
    ..In Aim #4 we will use laser microsurgery to determine: a) if "polar winds" are present during meiosis &mitosis in Drosophilaspermatocytes &..
  16. Microsurgical In-Situ Image Guidance with Optical Coherence Tomography
    George D Stetten; Fiscal Year: 2013
    ..The present grant extends the concept of in situ image guidance into the magnified action space of microsurgery. The surgical microscope is a well-established clinical tool, which provides an altered but usable form of hand-..
  17. OCT-Guided Free-Hand Semi-Automated Microsurgical Tool for Enhanced Retinal Surge
    Jin U Kang; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Contemporary retinal microsurgery is performed by skilled surgeons through operating microscopes, utilizing free hand techniques and manually operated precision micro-instruments...
  18. Impact of the Vascular System and CGM
    Don Kreutzer; Fiscal Year: 2013
    ..the cells, mediators and pathways that control angiogenesis, lymphangiogenesis using traditional and laser capture microsurgery technology and tissue from sensor implantation sites and correlate with CGM diabetic status.
  19. A genome assembly for Xenopus laevis
    DANIEL SOLEYMAN ROKHSAR; Fiscal Year: 2013
    ..For embryological experiments, the embryos are readily manipulated by microsurgery and by microinjection can be subjected to gain or loss of gene function...
  20. Molecular Determination of in vivo Cellular Calcium Signaling During Nerve Damage
    Christopher V Gabel; Fiscal Year: 2013
    ..field of regenerative medicine will be the ability to foster repair of neurons severed by injury, disease, or microsurgery. Intracellular calcium signaling plays a fundamental role in the neuronal response to traumatic damage, yet the ..
  21. 7T Small Animal MRI Scanner
    Srinivasan Mukundan; Fiscal Year: 2012
    ..vivarium for mice and rats, and an animal preparation lab complete with anesthesia resources for performing microsurgery. The animal imaging suite will consist of a control room, imaging bay and electronic support room...
  22. Comparative Genetics and Genomics of Xenopus
    DANIEL SOLEYMAN ROKHSAR; Fiscal Year: 2013
    ..For embryological experiments, the embryos are readily manipulated by microsurgery or microinjection, and can be subjected to both gain or loss of gene function...
  23. Advanced Optical Methods in Cell Biology
    Rudolf Oldenbourg; Fiscal Year: 2012
    ..based polarizing microscope (LC-PolScope), we are now broadening the scope of the project to include laser microsurgery and fluorescence anisotropy measurements for the development of advanced optical methods to manipulate and ..
  24. Integrated Multifunctional Imaging of Deep Vein Thrombosis
    Walter Scott; Fiscal Year: 2009
    ..into cancer research, diagnostic imaging and therapy monitoring, cellular imaging, small animal imaging, microsurgery, etc...
  25. An Active Handheld Micromanipulator
    Cameron N Riviere; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): Highly accurate positioning is fundamental to the performance of microsurgery. Vitreoretinal microsurgery in particular is among the most demanding of specialties in terms of positioning accuracy, and ..
  26. Infections and The Stability of Transplantation Tolerance
    Anita S Chong; Fiscal Year: 2013
    ..The Animal and Microsurgery Core (Core B, Alegre) will be responsible for animal breeding and heart transplantations necessary for the two ..
  27. Intra-operative confocal imaging-guided Mohs surgery
    Milind Rajadhyaksha; Fiscal Year: 2006
    ..frequently on older people and in high risk anatomical sites (near or on the eyes, mouth, nose, ears), precise microsurgery is necessary with minimum damage to the surrounding normal tissue...
  28. Minimally Invasive Micro-Nanoscale Tools and Devices for Medicine
    DAVID GRACIAS; Fiscal Year: 2009
    ..to develop an entire mobile and remotely actuated toolbox (including grippers, cutters and locomotors) for microsurgery. We have also engineered a new class of remote controlled containers for in vitro lab-on-a- chip applications ..
  29. Impact of hypertonic-hyperoncotic saline solutions on ischemia-reperfusion injury
    Anthony Durkin; Fiscal Year: 2009
    ..Early in the era of microsurgery, flap monitoring was performed based on clinical observation of skin color, capillary refill, and dermal ..
  30. Harmonically detected swept source OCT
    Kristen Peterson; Fiscal Year: 2007
    ..including plaque deposits, guidance of biopsy needles to aid in cancer diagnosis, and guidance tools for microsurgery. The specific objective of this project is the development of a high speed, high resolution optical method for ..
  31. NonInvasive Optical Imaging of Vocal Cord Microstructure
    Brian Wong; Fiscal Year: 2004
    ..and deep extent of both benign and malignant TVC neoplasms; and 3) facilitate real-time image guided microsurgery of the TVC, allowing more accurate tissue biopsies or surgery...
  32. Micro-Robotics for Minimally-Invasive Neurosurgery
    JAMES GOLDIE; Fiscal Year: 2009
    ..Current robotic technology, however, is unsuitable for neurosurgical microsurgery, because of the large working space that is required for the robots, and the fact that the robots were not ..
  33. Upgrade of Femtosecond Laser Sources for Optical Workstation
    KEVIN ELICEIRI; Fiscal Year: 2007
    ..A steerable, focused laser beam may be used for a variety of experimental manipulations such as laser microsurgery, optical trapping, localized photolysis of caged bioactive probes, and patterned photobleaching...
  34. Micro-Robotics for Minimally-Invasive Neurosurgery
    JAMES GOLDIE; Fiscal Year: 2004
    ..Current robotic technology, however, is unsuitable for neurosurgical microsurgery, because of the large working space that is required for the robots, and the fact that the robots were not ..
  35. Delta and Mesoderm Induction in Eucidaris Embryos
    Hyla Sweet; Fiscal Year: 2004
    ..Using sea urchin embryos, a variety of techniques, including methods in molecular biology, microsurgery and microscopy, can be combined to answer important questions about development...
  36. Cell Theranostics with Tunable Plasmonic Nanobubbles
    Dmitri O Lapotko; Fiscal Year: 2013
    ..is universal and can also be employed for detecting and manipulating specific molecules, or for precise microsurgery. PUBLIC HEALTH RELEVANCE: This project is aimed at the development of tunable devices (nanoprobes) called ..
  37. ETIOLOGY OF DISORDERS OF OLFACTORY EPITHELIA
    Joel Maruniak; Fiscal Year: 1991
    ..Naris closure and reopening will be performed by cautery, microsurgery and suture while the animal is under deep pentobarbital anesthesia...
  38. DEVELOPMENT OF NEURONS IN GUT--GROWTH FACTORS
    MILES EPSTEIN; Fiscal Year: 2001
    ..We will use in situ hybridization, immunocytochemistry, ELISA, and microsurgery to localize and quantitate GDNF expression...
  39. Complex differential spectral interferometry
    Daniel Kane; Fiscal Year: 2004
    ..structures s atherosclerotic plaques, detection of cancerous and pre-cancerous tissues, optical guidance during microsurgery and optical biopsy...
  40. NIR TUNABLE LASER TISSUE WELDING
    ROBERT ALFANO; Fiscal Year: 2007
    ..reduce risks of post-operative infection and scarring and provide an improved methodology for wound closure in microsurgery and endoscopic surgery...
  41. Image Guidance for Active Handheld Microsurgical Tools
    Cameron Riviere; Fiscal Year: 2007
    ..by applicant): This project will develop and validate a tool for increasing manual precision for retinal microsurgery. The proposed project will combine "Micron," a handheld tremor-reducing instrument (developed at CMU) with ..
  42. Stabilized Adaptive Optics Imaging Laser Microsurgery
    Daniel Hammer; Fiscal Year: 2004
    ..abstract_text> ..
  43. MINORITY SCHOOL FACULTY DEVELOPMENT AWARD
    MOHAMED BAYORH; Fiscal Year: 1990
    ..be done by the directional pulsed Doppler technique using VF-microprobes implanted on the respective arteries (microsurgery under anesthesia)...
  44. RESEARCH ON NEURULATION
    GARY SCHOENWOLF; Fiscal Year: 2001
    ..utilize several techniques with which the applicant has considerable expertise including whole-embryo culture, microsurgery, tissue grafting, cell labeling, time-lapse microscopy, histology, immunocytochemistry, and whole mount in situ ..
  45. DIODE LASER SYSTEM FOR FEEDBACK-CONTROLLED TISSUE WELD
    ROBERT REDIKER; Fiscal Year: 1993
    ..In oral surgery, removal of lower wisdom teeth can result in nerve injury requiring microsurgery to repair damaged peripheral nerves...
  46. ACTIVE ERROR CANCELING FOR MANUAL MICROMANIPULATION
    Cameron Riviere; Fiscal Year: 2001
    ..will be used both for microinjection and micromanipulation in the cell biology laboratory, and for clinical microsurgery, especially in vitreoretinal procedures...
  47. Self-organization of microtubules in interphase cells
    Vladimir Rodionov; Fiscal Year: 2006
    ..A combination of experimental techniques that include digital fluorescence microscopy, laser microsurgery, photoactivation and expression of dominant-negative subunits will be used to elucidate the mechanisms of self-..
  48. SHARED CONFOCAL MICROSCOPY FACILITY
    MYRON GINSBERG; Fiscal Year: 2003
    ..be located within our animalexperimentation laboratories, which contain instrumentation and resources for microsurgery, physiological monitoring, and laser-based photothrombosis...
  49. TISSUE BOUNDARIES SHAPING THE EARLY NERVOUS SYSTEM
    ANTONE JACOBSON; Fiscal Year: 1991
    ..embryos because neurulation in them has been best analyzed, and they are most amenable to the necessary microsurgery and labelling with lineage tracers...
  50. Bioswellable Absorbable Monofilament Sutures
    SHALABY SHALABY; Fiscal Year: 2007
    ..of swellable sutures with a focus on the absorbable monofilament type and those for use in laparoscopy and microsurgery. Accordingly, Phase I objective is synthesis of absorbable amphiphilic polyether esters and their evaluation ..
  51. Integrated optical imaging rat of mesentery
    Vladimir Zharov; Fiscal Year: 2004
    ..of this project include noninvasive high imaging of cellular structures in vivo, guidance of laser therapy and microsurgery, and quantitative characterization of blood and lymph microcirculation...
  52. MICROSURGICAL TRAINING MODEL
    Neil Watson; Fiscal Year: 1990
    ..Practitioners of microsurgery must be able to join together these vessels of approximately 1 mm surgeries that include repair of human digits,..
  53. PHYSIOLOGY OF PRE-OVIPOSITION BEHAVIOR
    MARC KLOWDEN; Fiscal Year: 1990
    ..Using techniques of microsurgery, the way in which mating influences this behavior and how pre- oviposition is terminated after oviposition will ..
  54. TENDON FORCE DURING OCCUPATIONAL HAND ACTIVITIES
    David Rempel; Fiscal Year: 2001
    ..The proposed study is a collaborative effort between the University of California Ergonomics Program (UCSF), Hand and Microsurgery (UCSP), Mechanical Engineering (UC Berkeley), and the Smith-Kettlewell Eye Research Institute.
  55. TELEPRESENCE FOR INTRA-ABDOMINAL AND ENDOSCOPIC SURGERY
    Philip Green; Fiscal Year: 1993
    ..of telepresence and demonstrate its applicability to closed intra-abdominal surgery, endoscopic surgery, and microsurgery. In these fields, the range of functions that can be performed with currently available instruments is ..
  56. ANTITHROMBOTIC TISSUE SOLDERS FOR MICROVASCULAR REPAIRS
    Robert Stewart; Fiscal Year: 2001
    ..this novel tissue repair technology will be evaluated for safety and efficacy for LAMA's use in reconstructive microsurgery. The program will also include the product development efforts necessary for FDA approval for clinical trials...
  57. MICRO-SURGICAL TRAINING MODELS AND TEACHING MATERIALS
    Richard McKinney; Fiscal Year: 1993
    ..The availability of a life-like microsurgery model for practice and instruction would play a significant role both in surgeons' initial training and in ..
  58. Serotonin and dopamine regulation of behavioral plasticity in C. elegans
    Michael Chao; Fiscal Year: 2006
    ..In addition to genetic screens, laser microsurgery of C. elegans neurons will be used to elucidate the cellular focus of dopamine action...
  59. MECHANISMS OF PRIMARY MESENCHYME MORPHOGENESIS
    CHARLES ETTENSOHN; Fiscal Year: 1993
    ..including isolation of embryonic extracellular matrices, micromanipulation of PMCs, cell ablation by UV microsurgery, and electron microscopy, 2)To analyze the molecular interactions that take place between the PMCs and their ..
  60. CONTROL OF NUCLEAR POSITIONING IN THE CILIATE STENTOR
    NOEL DE TERRA; Fiscal Year: 1980
    ..The main technique used will be microsurgery with electron microscopy as a subsidiary technique...
  61. SHAPE MEMORY ALLOYS--THEIR APPLICATION TO MICROSURGERY
    Steve Charles; Fiscal Year: 1990
    ..Commercially, the 3-DOF fine positioner can be used in the microsurgery area to position cutters, forceps, shears, illuminators and pics - the majority of the tools used in every ..
  62. Hand-held confocal line-scanner for intrasurgical use
    JAY EASTMAN; Fiscal Year: 2005
    ..development and clinical testing of a real-time hand-held confocal line-scanner is proposed for imaging-guided microsurgery applications...
  63. Novel Piezoelectric Translational and Rotary Motors
    Michael Strauss; Fiscal Year: 2001
    ..Therefore they will he a compact lightweight solution to better robotic systems for endoscopy microsurgery, and prosthetic devices...