Genomes and Genes
Summary: Excision of one or both of the parathyroid glands.
Publications373 found, 100 shown here
- Is total parathyroidectomy the treatment of choice for hyperparathyroidism in multiple endocrine neoplasia type 1?Francesco Tonelli
Department of Clinical Physiopathology, University of Florence, Medical SchoolFlorence, Italy
Ann Surg 246:1075-82. 2007The aim of the present report is to describe the results obtained with total parathyroidectomy (TPTX) guided by rapid intraoperative parathyroid hormone (PTH) evaluation, followed by immediate parathyroid autograft with fresh tissue.
- Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the third international workshopJohn P Bilezikian
Columbia University, College of Physicians and Surgeons, New York, New York 10032, USA
J Clin Endocrinol Metab 94:335-9. 2009..Asymptomatic primary hyperparathyroidism (PHPT) is a common clinical problem. The purpose of this report is to guide the use of diagnostics and management for this condition in clinical practice...
- Bone mineral density analysis in patients with primary hyperparathyroidism associated with multiple endocrine neoplasia type 1 after total parathyroidectomyFlavia L Coutinho
Endocrine Genetics Unit LIM 25, Division of Endocrinology, Hospital das Clinicas, University of Sao Paulo School of Medicine, Sao Paulo, Brazil
Clin Endocrinol (Oxf) 72:462-8. 2010Limited data have been reported on the effect of parathyroidectomy (PTx) on bone mineral density (BMD) in the setting of patients with hyperparathyroidism (HPT) associated with multiple endocrine neoplasia type 1 (MEN1)...
- Results of initial operation for hyperparathyroidism in patients with multiple endocrine neoplasia type 1Dina M Elaraj
Surgery Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, 9000 Rockville Pike, Bethesda, MD 20892, USA
Surgery 134:858-64; discussion 864-5. 2003..neoplasia type 1 (MEN1) is characterized by multiglandular disease and a propensity for recurrence after parathyroidectomy (PTx). This study analyzes outcomes of a cohort of MEN1 patients undergoing initial PTx at one institution.
- Parathyroid surgery in familial hyperparathyroid disordersT Carling
Department of Surgery, Yale University School of Medicine, New Haven, CT, USA
J Intern Med 257:27-37. 2005..Multiple endocrine neoplasia type 1 (MEN1) is treated with either subtotal parathyroidectomy or total parathyroidectomy with immediate heterotopic autotransplantation of parathyroid tissue...
- Osteoporosis in multiple endocrine neoplasia type 1: severity, clinical significance, relationship to primary hyperparathyroidism, and response to parathyroidectomyJ R Burgess
Department of Diabetes, Royal Hobart Hospital, Australia
Arch Surg 134:1119-23. 1999..hyperparathyroidism associated with MEN 1 is typically recurrent, despite initially successful subtotal parathyroidectomy. Osteoporosis is considered a complication of sporadic PHPT and an indication for parathyroidectomy...
- Presentation of asymptomatic primary hyperparathyroidism: proceedings of the third international workshopShonni J Silverberg
Columbia University College of Physicians and Surgeons, 630 West 168th Street, PH 8W 864, New York, New York 10032, USA
J Clin Endocrinol Metab 94:351-65. 2009..We present the results of a literature review on issues arising from the clinical presentation and natural history of PHPT...
- Parathyroidectomy decreases systolic and diastolic blood pressure in hypertensive patients with primary hyperparathyroidismAliya Heyliger
Division of General Internal Medicine, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
Surgery 146:1042-7. 2009..The purpose of this study was to determine the effect of parathyroidectomy on systolic and diastolic blood pressures (BP) in hypertensive patients with PHPT.
- Long-term effects of parathyroidectomy on hypertension prevalence and circadian blood pressure profile in primary hyperparathyroidismCarlos A Feldstein
Hypertension Program, Hospital de Clinicas Jose de San Martin, School of Medicine, Universidad de Buenos Aires, Buenos Aires 1120, Argentina
Clin Exp Hypertens 32:154-8. 2010..of hypertension in patients with primary hyperparathyroidism (PHPT), previously and after follow-up of parathyroidectomy. A group of 46 consecutive patients with sporadic PHPT due to adenoma undergoing surgery were followed an ..
- The natural history of primary hyperparathyroidism with or without parathyroid surgery after 15 yearsMishaela R Rubin
Department of Medicine, Columbia University, College of Physicians and Surgeons, 630 West 168th Street, New York, New York 10032, USA
J Clin Endocrinol Metab 93:3462-70. 2008..We previously reported that calciotropic indices and bone mineral density (BMD) are stable in untreated patients for up to a decade, whereas after parathyroidectomy, normalization of biochemistries and increases in BMD ensue.
- Prospective study of surgery for primary hyperparathyroidism (HPT) in multiple endocrine neoplasia-type 1 and Zollinger-Ellison syndrome: long-term outcome of a more virulent form of HPTJeffrey A Norton
Department of Surgery, Stanford University Medical Center, Stanford, CA 94305, USA
Ann Surg 247:501-10. 2008..Surgery for parathyroid hyperplasia is tricky and difficult. Long-term outcome in ZES/MEN1/HPT is not well known...
- Validity and limits of intraoperative parathyroid hormone monitoring during minimally invasive parathyroidectomy: a 10-year experienceAlexandra Ozimek
Chirurgische Klinik Innenstadt, Ludwig Maximilians University, Munich, Germany
Surg Endosc 24:3156-60. 2010..of intraoperative intact parathyroid hormone monitoring allows the success of minimally invasive parathyroidectomy to be ensured during the operation...
- Parathyroidectomy rates among United States dialysis patients: 1990-1999Bryan Kestenbaum
University of Washington Department of Medicine, Division of Nephrology, Seattle, Washington 98195, USA
Kidney Int 65:282-8. 2004..It is not known how changes in medical therapy might impact the parathyroidectomy (PTX) rate among dialysis patients...
- Endoscopic parathyroidectomyAhmad Assalia
Department of Surgery, Mount Sinai Medical Center, New York, NY 10029, USA
Otolaryngol Clin North Am 37:871-86, xi. 2004This article describes the techniques of endoscopic and endoscopic assisted parathyroidectomy, with a special emphasis on the accumulated experience as well as the advantages and drawbacks of these novel techniques.
- Vitamin D metabolites and skeletal consequences in primary hyperparathyroidismB Moosgaard
Aarhus Bone and Mineral Research Group Department of Endocrinology and Metabolism C, Aarhus University Hospital, DK 8000 Aarhus C, Denmark
Clin Endocrinol (Oxf) 68:707-15. 2008..However, successful parathyroidectomy causes an increase in BMD especially at sites rich in trabecular bone...
- Subtotal parathyroidectomy as an adequate treatment for primary hyperparathyroidism in multiple endocrine neoplasia type 1Johnathan G H Hubbard
Department of Endocrine Surgery, University Hospital La Timone, Marseille, France
Arch Surg 141:235-9. 2006..It has been advocated that reoperations for recurrent disease are easier to perform after total parathyroidectomy (TP) with autotransplantation than after subtotal parathyroidectomy (SP)...
- Consequences of targeted parathyroidectomy guided by localization studies without intraoperative parathyroid hormone monitoringDenise M Carneiro-Pla
Department of Surgery, Miller School of Medicine, University of Miami, Miami, FL, USA
J Am Coll Surg 202:715-22. 2006....
- Surgery for asymptomatic primary hyperparathyroidism: proceedings of the third international workshopRobert Udelsman
Department of Surgery, Yale University School of Medicine, New Haven, Connecticut 06510, USA
J Clin Endocrinol Metab 94:366-72. 2009..An international workshop on primary hyperparathyroidism (PHPT) was convened on May 13, 2008, to review and update the previous summary statement on the management of asymptomatic PHPT published in 2002...
- Six hundred fifty-six consecutive explorations for primary hyperparathyroidismRobert Udelsman
Department of Surgery, Yale University School of Medicine, New Haven, Connecticut, USA
Ann Surg 235:665-70; discussion 670-2. 2002To review the outcomes of 656 consecutive parathyroid explorations performed by a single surgeon and to compare the results of conventional and minimally invasive parathyroidectomy (MIP) techniques.
- Coronary microvascular dysfunction induced by primary hyperparathyroidism is restored after parathyroidectomyElena Osto
Department of Cardiologic, Thoracic and Vascular Sciences, University of Padova, Padua, Italy
Circulation 126:1031-9. 2012..However, data on the association between asymptomatic PHPT and cardiovascular risk are lacking. We assessed coronary flow reserve (CFR) as a marker of coronary microvascular function in asymptomatic PHPT of recent onset...
- Minimally invasive radioguided parathyroidectomy for hyperparathyroidismYoshifumi Ikeda
Department of Surgery, Teikyo University School of Medicine, 2 11 1 Kaga, Itabashi ku, Tokyo, 173 8605, Japan
Ann Nucl Med 24:233-40. 2010..In patients with HPT who meet the indications for parathyroidectomy, complete surgical resection of all hyperfunctioning parathyroid tissue is essential for the curative ..
- The outcome of subtotal parathyroidectomy for the treatment of hyperparathyroidism in multiple endocrine neoplasia type 1J R Burgess
Department of Diabetes and Endocrine Services, Royal Hobart Hospital, Australia
Arch Surg 133:126-9. 1998The efficacy of subtotal parathyroidectomy for the treatment of hyperparathyroidism in multiple endocrine neoplasia type 1 (MEN 1) is unclear. The long-term outcome and optimal timing of operation remain controversial.
- A very high incidence of low 25 hydroxy-vitamin D serum concentration in a French population of patients with primary hyperparathyroidismP Boudou
Department of Hormonal Biology, Hopital Saint Louis, Paris, France
J Endocrinol Invest 29:511-5. 2006....
- Elucidating mechanisms of recurrent laryngeal nerve injury during thyroidectomy and parathyroidectomySamuel K Snyder
Department of Surgery, Scott and White Memorial Hospital, Temple, TX 76508, USA
J Am Coll Surg 206:123-30. 2008Intraoperative nerve monitoring during thyroidectomy, parathyroidectomy, or related central neck procedures can elucidate actual or potential mechanisms of recurrent laryngeal nerve (RLN) injury, especially visually intact nerves, which ..
- Comparison of intraoperative iPTH assay (QPTH) criteria in guiding parathyroidectomy: which criterion is the most accurate?Denise M Carneiro
DeWitt Daughtry Family Department of Surgery, University of Miami Jackson Memorial, PO Box 016310 M 875, Miami, FL 33101, USA
Surgery 134:973-9; discussion 979-81. 2003..To improve specificity or to decrease the cost of QPTH, several criteria have been used to predict complete excision. This study compares the Miami criterion with other published QPTH criteria in predicting operative outcome...
- Advantages of recurrent laryngeal nerve identification in thyroidectomy and parathyroidectomy and the importance of preoperative and postoperative laryngoscopic examination in more than 1000 nerves at riskMartin Steurer
Department of Otorhinolaryngology Head and Neck Surgery, Vienna Medical School, General Hospital Vienna, Waeringer Guertel 18 20, A 1090 Vienna, Austria
Laryngoscope 112:124-33. 2002..Besides, misdiagnosis is not uncommon. Therefore, preoperative and postoperative laryngoscopic examination was given attention...
- Bisphosphonates can reduce bone hunger after parathyroidectomy in patients with primary hyperparathyroidism and osteitis fibrosa cysticaTatiana Clementino Pinto Toscano de França
Centro de Osteoporose de Pernambuco, Department of Endocrinology, Hospital Agamenon Magalhães SUS, Universidade de Pernambuco, Recife, PE, Brazil
Rev Bras Reumatol 51:131-7. 2011To assess the effect of bisphosphonates on post-parathyroidectomy hypocalcemia in patients with osteitis fibrosa cystica.
- Pulse wave velocity in primary hyperparathyroidism and effect of surgical therapyJan Rosa
3rd Department of Internal Medicine, General Faculty Hospital, First Medical Faculty, Charles University, Prague, Czech Republic
Hypertens Res 34:296-300. 2011..Subsequently, we examined the effect of parathyroidectomy (PTX) on arterial stiffness...
- Early parathyroidectomy increases bone mineral density in patients with mild primary hyperparathyroidism: a prospective and randomized studyErik G Almqvist
Department of Medicine, Central Hospital, SE 541 85 Skövde, Sweden
Surgery 136:1281-8. 2004..This prospective and randomized study was undertaken to evaluate skeletal effects of delayed surgical treatment in such patients...
- Recurrent renal hyperparathyroidism caused by parathyromatosisSusumu Matsuoka
Department of Transplant and Endocrine Surgery, Nagoya Daini Red Cross Hospital, Nagoya, Japan
World J Surg 31:299-305. 2007..In renal HPT, the stimuli of the parathyroid cells persist after parathyroidectomy (PTx), and for this reason, parathyromatosis might be important in renal HPT.
- Parathyroid surgical failures with sufficient decline of intraoperative parathyroid hormone levels: unobserved multiple endocrine neoplasia as an explanationJohan Westerdahl
Department of Surgery, Lund University Hospital, Lund, Sweden
Arch Surg 141:589-94. 2006..A sufficient decline in levels of parathyroid hormone measured intraoperatively (ioPTH) precludes early and late surgical failures...
- High success rate of parathyroid reoperation may be achieved with improved localization diagnosisOla Hessman
Department of Surgery, University Hospital, 751 85 Uppsala, Swede
World J Surg 32:774-81; discussion 782-3. 2008..We report the use of consistently applied localization diagnosis to yield high success rates in parathyroid reoperations...
- Evolution of maxillofacial brown tumors after parathyroidectomy in primary hyperparathyroidismJaime Alonso Reséndiz-Colosia
Department of Head and Neck Surgery, Hospital de Oncologia, Centro Medico Nacional Siglo XXI, Instituto Mexicano del Seguro Social, Mexico City, Mexico
Head Neck 30:1497-504. 2008Brown tumor occasionally affects the facial bones. Clinically, these lesions can be mistaken for a neoplasm. Opinions are divided on the course of management of the bony lesions once parathyroidectomy has been carried out.
- The superiority of minimally invasive parathyroidectomy based on 1650 consecutive patients with primary hyperparathyroidismRobert Udelsman
Department of Surgery, Yale University School of Medicine, New Haven, CT 06525, USA
Ann Surg 253:585-91. 2011To compare the results of minimally invasive parathyroidectomy (MIP) and conventional parathyroid surgery.
- Cardiac function in mild primary hyperparathyroidism and the outcome after parathyroidectomyP Farahnak
Section of Surgery, Department of Clinical Science and Education, Karolinska Institutet Södersjukhuset, S 118 83 Stockholm, Sweden
Eur J Endocrinol 163:461-7. 2010..Using sensitive echocardiographic methods, we compared cardiac structure and function in patients with mild PHPT and in healthy controls, and evaluated the changes after parathyroidectomy (PTX).
- Incision length for standard thyroidectomy and parathyroidectomy: when is it minimally invasive?Laurent Brunaud
Department of Surgery, University of California, San Francisco, USA
Arch Surg 138:1140-3. 2003Current techniques for open conventional thyroidectomy or parathyroidectomy have evolved to enable a shorter incision (main proposition), and the length of the incision is influenced by objective factors.
- Malignant thymic carcinoid is not prevented by transcervical thymectomy in multiple endocrine neoplasia type 1J R Burgess
Department of Diabetes, Royal Hobart Hospital, Tasmania, Australia
Clin Endocrinol (Oxf) 55:689-93. 2001..This is the first report of a malignant thymic carcinoid occurring in an MEN 1 patient following prior parathyroidectomy and transcervical thymectomy...
- Minimally invasive parathyroidectomy using local anesthesia with intravenous sedation and targeted approachesMaisie L Shindo
SUNY at Stony Brook, Stony Brook, NY 11794, USA
Otolaryngol Head Neck Surg 138:381-7. 2008Minimally invasive parathyroidectomy (MIP) is generally performed under general anesthesia. This study evaluates the efficacy and safety of MIP performed under intravenous sedation with local anesthesia.
- Vitamin D3 deficiency is associated with late-onset hypocalcemia after minimally invasive parathyroidectomy in a vitamin D borderline areaBrian Hung Hin Lang
Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong SAR, China
World J Surg 34:1350-5. 2010..We aimed to examine the clinicopathologic features and short-term outcomes of vitamin D(3)-deficient patients after minimally invasive parathyroidectomy (MIP).
- Minimally invasive focused parathyroidectomy without using intraoperative parathyroid hormone monitoring or gamma probeM Haciyanli
Ataturk Training and Research Hospital, Second Surgery, Izmir, Turkey
J Postgrad Med 55:242-6. 2009Minimally invasive parathyroidectomy (MIP) is widely used worldwide for the treatment of primary hyperparathyroidism (pHPT). It is usually combined with a perioperative adjunct for high success rate.
- Minimally invasive parathyroidectomy using cervical block: reasons for conversion to general anesthesiaTobias Carling
Yale University School of Medicine, New Haven, CT 06510, USA
Arch Surg 141:401-4; discussion 404. 2006We investigated the frequency and reasons for conversion from cervical block anesthesia to general anesthesia (GA) in patients undergoing minimally invasive parathyroidectomy for primary hyperparathyroidism.
- Hyperparathyroidism in hereditary syndromes: special expressions and special managementsStephen J Marx
Metabolic Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892 1802, USA
J Bone Miner Res 17:N37-43. 2002..Both cause hypercalcemia from birth and atypical HPT that always and uniquely persists after subtotal parathyroidectomy. Their HPT is likely polyclonal and nonneoplastic...
- Surgical treatment for primary hyperparathyroidism in Hong Kong: changes in clinical pattern over 3 decadesChung Yau Lo
Department of Surgery, University of Hong Kong Medical Centre, Queen Mary Hospital, Pokfulam, Hong Kong
Arch Surg 139:77-82; discussion 82. 2004..The clinical pattern of primary HPT has undergone a significant evolution in Western countries. A similar change can be documented in a geographic region where this condition is considered to be relatively uncommon...
- Long-term results of less than total parathyroidectomy for hyperparathyroidism in multiple endocrine neoplasia type 1Laurent C Arnalsteen
Department of General and Endocrine Surgery, University Hospital of Lille, 1 rue Michel Polonovski, 59037 Lille Cedex, France
Surgery 132:1119-24; discussion 1124-5. 2002Our aim was to assess long-term results after less than total parathyroidectomy for hyperparathyroidism in multiple endocrine neoplasia type 1.
- An 18-month open-label trial of teriparatide in patients with previous parathyroidectomy at continued risk for osteoporotic fractures: an exploratory studyBarry S Horowitz
Metabolic Research Institute, Inc, West Palm Beach, FL, USA
Endocr Pract 17:377-83. 2011To determine whether teriparatide increases lumbar spine bone mineral density (BMD) in patients who have undergone parathyroidectomy for primary hyperparathyroidism (PHPT) and are at continued risk for fracture.
- Randomized clinical trial comparing open with video-assisted minimally invasive parathyroid surgery for primary hyperparathyroidismO Hessman
Department of Surgical Sciences, Uppsala University, Uppsala, Sweden
Br J Surg 97:177-84. 2010Previous studies of video-assisted techniques for parathyroidectomy in patients with primary hyperparathyroidism have found similar or better results compared with bilateral neck exploration...
- Persistent parathyroid hormone elevation following curative parathyroidectomy for primary hyperparathyroidismElizabeth A Mittendorf
Department of Surgery, MetroHealth Medical Center, 2500 MetroHealth Dr, H920, Cleveland, OH 44109 1998, USA
Arch Otolaryngol Head Neck Surg 128:275-9. 2002Persistent elevation of parathyroid hormone (PTH) levels following parathyroidectomy may indicate residual abnormal parathyroid tissue.
- Elevated parathyroid hormone levels after parathyroidectomy for primary hyperparathyroidismAviram Mizrachi
Department of Otorhinolaryngology Head and Neck Surgery, Rabin Medical Center, Petach Tikva, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel
Head Neck 31:1456-60. 2009Curative parathyroidectomy is associated with elevated levels of parathyroid hormone (PTH) with eucalcemia. This study sought to determine the frequency, clinical significance, and risk factors of this finding.
- Quick intraoperative parathyroid hormone assay: surgical adjunct to allow limited parathyroidectomy, improve success rate, and predict outcomeGeorge L Irvin
DeWitt Daughtry Family Department of Surgery, University of Miami Jackson Memorial Hospital, P O Box 016310 M 875, Miami, FL 33101, USA
World J Surg 28:1287-92. 2004..The QPTH-guided limited parathyroidectomy (LPX) must be able to identify multiglandular disease (MGD), predict a successful outcome, and have a low ..
- Randomized clinical trial comparing regional and general anaesthesia in minimally invasive video-assisted parathyroidectomyP Miccoli
Department of Surgery, Ospedale Santa Chiara, University of Pisa, Italy
Br J Surg 92:814-8. 2005This randomized clinical trial was performed in a single institution to compare the results of minimally invasive video-assisted parathyroidectomy (MIVAP) conducted under regional anaesthesia (RA) or general anaesthesia (GA).
- Reoperative parathyroidectomy: an algorithm for imaging and monitoring of intraoperative parathyroid hormone levels that results in a successful focused approachTina W F Yen
Section of Endocrine Surgery, Division of General Surgery, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Surgery 144:611-9; discussion 619-21. 2008..and use of intraoperative parathyroid hormone (IOPTH) levels are changing the approach to reoperative parathyroidectomy (ReopPTX)...
- Risks and consequences of incidental parathyroidectomy during thyroid resectionRebecca S Sippel
Department of Surgery, University of Wisconsin, Madison, Wisconsin 53792, USA
ANZ J Surg 77:33-6. 2007..Inadvertent removal of the parathyroid glands during elective thyroid surgery occurs more frequently in certain high-risk patients and can lead to symptomatic hypocalcaemia...
- Rapid intraoperative immunoassay of parathyroid hormone and other hormones: a new paradigm for point-of-care testingLori J Sokoll
Department of Pathology, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Clin Chem 50:1126-35. 2004..of the use of a rapid assay for the measurement of intact parathyroid hormone (PTH) in patients undergoing parathyroidectomy for hyperparathyroidism was reported in 1988...
- Incidental parathyroidectomy during thyroid surgery: an underappreciated complication of thyroidectomyGeorge H Sakorafas
Department of Surgery, 251 Hellenic Air Force Hospital, 19 21 Arkadias Street, Athens, GR 115 26, Greece
World J Surg 29:1539-43. 2005The aim of this study was to investigate the incidence, risk factors, and clinical relevance of incidental parathyroidectomy during thyroid surgery...
- Minimally invasive parathyroidectomy: benefits and requirements of localization, diagnosis, and intraoperative PTH monitoring. long-term resultsDouglas L Fraker
Department of Surgery, University of Pennsylvania Health System, Philadelphia, PA 19104, USA
World J Surg 33:2256-65. 2009Surgery is the only curative treatment for primary hyperparathyroidism. Initial parathyroidectomy procedures fail due to ectopic gland location and unappreciated multigland disease.
- Evaluation for concomitant thyroid nodules and primary hyperparathyroidism in patients undergoing parathyroidectomy or thyroidectomyShane Y Morita
Endocrine Surgery Section, Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, MD, USA
Surgery 144:862-6; discussion 866-8. 2008..In this article, we present a single-center experience with the incidence of concomitant thyroid nodular disease and primary hyperparathyroidism in patients who underwent parathyroidectomy or thyroidectomy.
- Evaluation of serum calcium levels in predicting hypoparathyroidism after total/near-total thyroidectomy or parathyroidectomyD J Bentrem
Division of Gastrointestinal and Endocrine Surgery, Northwestern University Medical School, Chicago, Illinois, USA
Am Surg 67:249-51; discussion 251-2. 2001..We analyzed 120 consecutive patients having total/near-total thyroidectomy and/or parathyroidectomy between April 1998 and October 1999...
- Evaluation of the performance and clinical impact of a rapid intraoperative parathyroid hormone assay in conjunction with preoperative imaging and concise parathyroidectomyL R Johnson
Washington University School of Medicine, Department of Pathology and Immunology, Barnes-Jewish Hospital, St. Louis, MO 63110, USA
Clin Chem 47:919-25. 2001..stay, and pre- and postoperative calcium values were compared between a group of 49 patients undergoing parathyroidectomy where the intraoperative PTH assay was used in conjunction with preoperative imaging, and a historical ..
- Total parathyroidectomy reduces elevated circulating fibroblast growth factor 23 in advanced secondary hyperparathyroidismTetsuhiko Sato
Department of Surgery, Renal Center, Nagoya Second Red Cross Hospital, Nagoya, Japan
Am J Kidney Dis 44:481-7. 2004..The aim of this study is to examine the association of advanced secondary hyperparathyroidism with circulating FGF-23 levels...
- Medical observation, compared with parathyroidectomy, for asymptomatic primary hyperparathyroidism: a prospective, randomized trialJens Bollerslev
Section of Endocrinology, Department of Medicine, Rikshospitalet Radiumhospitalet Medical Center, National University Hospital, N 0027 Oslo, Norway
J Clin Endocrinol Metab 92:1687-92. 2007..The clinical presentation of primary hyperparathyroidism (pHPT) has changed during the last half century, and the diagnosis is now more often made by chance in patients with no specific symptoms...
- Fracture risk after parathyroidectomy among chronic hemodialysis patientsKyle D Rudser
Division of Biostatistics, Harborview Medical Center, University of Washington, Seattle, WA 98104 2499, USA
J Am Soc Nephrol 18:2401-7. 2007The impact of parathyroidectomy (PTX) on the long-term risks for hip and other fractures is unknown. Uncontrolled case series have reported an increase in bone mineral density after PTX...
- Surgery for multiple endocrine neoplasia type 1-associated primary hyperparathyroidismJ Waldmann
Department of Visceral, Thoracic and Vascular Surgery, University Hospital Giessen and Marburg, Marburg, Germany
Br J Surg 97:1528-34. 2010..It is uncertain which operative procedure provides the best outcome with regard to long-term normocalcaemia...
- Unilateral versus bilateral neck exploration for primary hyperparathyroidism: a prospective randomized controlled trialAnders Bergenfelz
Department of Surgery, Lund University Hospital, Lund, Sweden
Ann Surg 236:543-51. 2002..To compare unilateral and bilateral neck exploration for primary hyperparathyroidism in a prospective randomized controlled trial...
- Evaluation of Halle, Miami, Rome, and Vienna intraoperative iPTH assay criteria in guiding minimally invasive parathyroidectomyMarcin Barczynski
Department of Endocrine Surgery, Jagiellonian University College of Medicine, 37 Pradnicka Street, 31 202, Krakow, Poland
Langenbecks Arch Surg 394:843-9. 2009Intraoperative parathyroid hormone assay (IOPTH) has been used during minimally invasive parathyroidectomy (MIP) to predict operative success...
- Is intraoperative parathyroid hormone assay mandatory for the success of targeted parathyroidectomy?Alejandra Gil-Cárdenas
Department of Surgery, Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City, Mexico
J Am Coll Surg 204:286-90. 2007Minimally invasive parathyroidectomy has become the first surgical option for patients with primary hyperparathyroidism (HPT) in many places...
- The surgeon's armamentarium to the surgical treatment of primary hyperparathyroidismJames A Lee
Department of Surgery, College of Physicians and Surgeons of Columbia University, New York Presbyterian Hospital, New York, New York, USA
J Surg Oncol 89:130-5. 2005b>Parathyroidectomy cures the vast majority of patients with primary hyperparathyroidism (HPT)...
- Reassessment of parathyroid hormone monitoring during parathyroidectomy for primary hyperparathyroidism after 2 preoperative localization studiesAtul A Gawande
Harvard School of Public Health, Boston, MA, USA
Arch Surg 141:381-4; discussion 384. 2006..with 2 localization studies showing the same single location of parathyroid disease, use of intraoperative parathyroid hormone (IOPTH) measurement does not significantly increase the success of minimally invasive parathyroidectomy.
- Phosphorus overload and PTH induce aortic expression of Runx2 in experimental uraemiaFabiana G Graciolli
Nephrology Division, Department of Internal Medicine, University of Sao Paulo, Sao Paulo, Brazil
Nephrol Dial Transplant 24:1416-21. 2009..In addition, Runx2 has been detected in calcified arteries of CKD patients. However, the in vivo effect of phosphate and PTH on Runx2 expression remains unknown...
- Up-to-date on parathyroid carcinoma: analysis of an experience of 19 casesMaurizio Iacobone
Endocrine Surgery Unit, Department of Surgical and Gastroenterological Sciences, University of Padua, School of Medicine, Padova, Italy
J Surg Oncol 88:223-8. 2004..Parathyroid carcinoma (PC) is a rare disease; experience with its management is limited. The aim of this retrospective study was to evaluate a relatively large series of patients suffering from PC...
- The optimal surgical treatment for primary hyperparathyroidism in MEN1 patients: a systematic reviewJennifer M J Schreinemakers
Department of Surgery, University Medical Center Utrecht, Heidelberglaan 100, 3584CX, Utrecht, The Netherlands
World J Surg 35:1993-2005. 2011..The optimal surgical approach for patients with primary hyperparathyroidism (pHPT) and multiple endocrine neoplasia 1 (MEN1) is controversial. We sought to determine the optimal type of surgery for pHPT in MEN1...
- Asymptomatic hyperparathyroidism: a medical misnomer?Nancy D Perrier
Department of Surgical Oncology, University of Texas M D Anderson Cancer Center, 1515 Holcombe Boulevard 444, Houston, TX 77030, USA
Surgery 137:127-31. 2005
- Focused cervical exploration for primary hyperparathyroidism without intraoperative parathyroid hormone monitoring or use of the gamma probeSteven R Jacobson
Division of Gastroenterologic and General Surgery, Mayo Clinic and Mayo Foundation, Rochester, Minnesota 55905, USA
World J Surg 28:1127-31. 2004..Further experience with this surgical approach seems warranted to determine the overall cure rate, operative morbidity, and the sensitivity and specificity of preoperative localization studies...
- Results of video-assisted parathyroidectomy: single institution's six-year experiencePaolo Miccoli
Department of Surgery, University of Pisa, Via Roma 67, 56100 Pisa, Italy
World J Surg 28:1216-8. 2004Endoscopic surgery for primary hyperparathyroidism (PHPT) started in 1996 with a parathyroidectomy performed by Michel Gagner...
- Surgery or surveillance for mild asymptomatic primary hyperparathyroidism: a prospective, randomized clinical trialElena Ambrogini
Department of Endocrinology, University of Pisa, Via Paradisa 2, 56124 Pisa, Italy
J Clin Endocrinol Metab 92:3114-21. 2007It is unclear whether patients with asymptomatic primary hyperparathyroidism (PHPT) do better with parathyroidectomy (PTx) as compared with conservative medical management.
- Effect of treatment with depot somatostatin analogue octreotide on primary hyperparathyroidism (PHP) in multiple endocrine neoplasia type 1 (MEN1) patientsAntongiulio Faggiano
Department of Molecular and Clinical Endocrinology and Oncology, Federico II University of Naples, Naples, Italy
Clin Endocrinol (Oxf) 69:756-62. 2008....
- Intraoperative parathyroid hormone monitoringWilliam B Inabnet
Department of Surgery, Section of Endocrine Surgery, College of Physicians and Surgeons of Columbia University, New York Presbyterian Hospital, 161 Fort Washington Avenue, Room 820, New York, NY 10032, USA
World J Surg 28:1212-5. 2004The principles of minimally invasive parathyroidectomy include the successful preoperative localization of a solitary adenoma, a targeted operative approach that does not disturb the normal parathyroid glands, and intraoperative ..
- Conventional bilateral cervical exploration versus open minimally invasive parathyroidectomy under local anaesthesia for primary hyperparathyroidismA Bergenfelz
Department of Surgery, Philipps University Marburg, Baldingerstrasse, D 35033 Marburg, Germany
Br J Surg 92:190-7. 2005Minimally invasive parathyroidectomy (MIP) has been introduced for the treatment of patients with primary hyperparathyroidism (pHPT)...
- Randomized controlled clinical trial of surgery versus no surgery in patients with mild asymptomatic primary hyperparathyroidismD Sudhaker Rao
Division Head, Bone and Mineral Metabolism, Department of Internal Medicine, Henry Ford Hospital, Room E 1607, 2799 West Grand Boulevard, Detroit, Michigan 48202 2689, USA
J Clin Endocrinol Metab 89:5415-22. 2004b>Parathyroidectomy is the definitive therapy for patients with symptomatic primary hyperparathyroidism. However, the role of surgery in mild asymptomatic primary hyperparathyroidism remains controversial...
- Metabolic abnormalities in patients with normocalcemic hyperparathyroidism detected at a population-based screeningEmil Hagström
Endocrine Unit, Department of Surgical Sciences, Uppsala University, University Hospital, SE 751 85 Uppsala, Sweden
Eur J Endocrinol 155:33-9. 2006..aim was to explore the occurrence of these metabolic abnormalities in individuals with normocalcemic pHPT identified in a population-based screening, and the effects of parathyroidectomy vs conservative treatment on metabolic variables.
- Minimally invasive parathyroidectomy without intraoperative parathyroid hormone monitoring in patients with primary hyperparathyroidismR Mihai
Department of Endocrine Surgery, John Radcliffe Hospital, Oxford, UK
Br J Surg 94:42-7. 2007Minimally invasive parathyroidectomy (MIP) is the preferred operation for patients with primary hyperparathyroidism (HPT) and positive preoperative imaging...
- Outpatient minimally invasive parathyroidectomy is safe for elderly patientsSusanna H Shin
Department of Surgery, Eastern Virginia Medical School, Norfolk, VA, USA
J Am Coll Surg 208:1071-6. 2009..Because PHPT is more common in the elderly, we sought to compare indications and complications of minimally invasive parathyroidectomy in patients 70 years of age and older (elderly) with their younger counterparts.
- Minimally invasive parathyroidectomy using the lateral focused mini-incision technique without intraoperative parathyroid hormone monitoringT Pang
University of Sydney Endocrine Surgical Unit, Royal North Shore Hospital, Sydney, New South Wales, Australia
Br J Surg 94:315-9. 2007Minimally invasive parathyroidectomy (MIP) involves scan-directed removal of a single adenoma through a 2.0-cm mini-incision without intraoperative monitoring...
- Hyperparathyroidism in patients over 80: clinical characteristics and their ability to undergo outpatient parathyroidectomyDouglas Politz
Norman Endocrine Surgery Clinic, Tampa, Florida 33613, USA
Thyroid 17:333-9. 2007..We evaluated the presentation of patients over 80 with primary hyperparathyroidism (PHPT) and their ability to tolerate outpatient, minimally invasive parathyroidectomy.
- What is the clinical significance of an elevated parathyroid hormone level after curative surgery for primary hyperparathyroidism?Li Ning
Endocrine Surgery Research Laboratories, Department of Surgery, University of Wisconsin, and the University of Wisconsin Paul P Carbone Comprehensive Cancer Center, Madison, Wisconsin, USA
Ann Surg 249:469-72. 2009..To determine the clinical significance of ePTH and if it is a potential risk factor for recurrent HPT, we reviewed our experience...
- What is the link between nonlocalizing sestamibi scans, multigland disease, and persistent hypercalcemia? A study of 401 consecutive patients undergoing parathyroidectomyBill Chiu
Department of Surgery, Division of Gastrointestinal and Endocrine Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA
Surgery 140:418-22. 2006..We hypothesized that nonlocalizing sestamibi scans would correlate with multigland disease and persistent primary hyperparathyroidism...
- Focused approach to parathyroidectomyTobias Carling
Department of Surgery, Yale University School of Medicine, 330 Cedar Street, FMB 102, Box 208062, New Haven, CT 06510, USA
World J Surg 32:1512-7. 2008Minimally invasive parathyroidectomy is performed after preoperative parathyroid localization-usually with high-quality sestamibi scans and/or ultrasonography-often under cervical block anesthesia during which a limited exploration is ..
- Video-assisted parathyroidectomy via the lateral approach vs conventional surgery in the treatment of sporadic primary hyperparathyroidism: results of a case-control studyJ F Henry
Department of General and Endocrine Surgery, University Hospital La Timone, Boulevard Jean Moulin, 13385 Marseilles Cedex 5, France
Surg Endosc 15:1116-9. 2001We previously demonstrated that minimally invasive video-assisted parathyroidectomy (VAP) can be performed via a lateral approach on the line of the sternocleidomastoid muscle...
- Minimally invasive video-assisted parathyroidectomy versus open minimally invasive parathyroidectomy for a solitary parathyroid adenoma: a prospective, randomized, blinded trialMarcin Barczynski
Department of Endocrine Surgery, 3rd Chair of General Surgery, Jagiellonian University College of Medicine, 37 Pradnicka Street, Krakow, 31 202, Poland
World J Surg 30:721-31. 2006A variety of minimally invasive parathyroidectomy (MIP) techniques have been currently introduced to surgical management of primary hyperparathyroidism (pHPT) caused by a solitary parathyroid adenoma...
- Effect of minimally invasive radioguided parathyroidectomy on efficacy, length of stay, and costs in the management of primary hyperparathyroidismR E Goldstein
Divisions of Surgical Oncology and Endocrinology and the Department of Nuclear Medicine, Vanderbilt University Medical Center, and the Nashville VA Medical Center, Nashville, Tennessee 37232, USA
Ann Surg 231:732-42. 2000....
- Radioguided parathyroidectomy for hyperparathyroidism in the reoperative neckSusan C Pitt
Section of Endocrine Surgery, Department of Surgery, University of Wisconsin, Madison, WI, USA
Surgery 146:592-8; discussion 598-9. 2009The purpose of this study was to determine if radioguided parathyroidectomy (RGP) is effective for hyperparathyroidism (HPT) in the reoperative neck.
- Management of calcium refilling post-parathyroidectomy in end-stage renal diseaseMario Cozzolino
Renal Unit, San Paolo Hospital, University of Milan, Milan, Italy
J Nephrol 17:3-8. 2004Management of post-parathyroidectomy hypocalcemia in dialysis patients is not well defined. We reviewed published approaches to treatment in an effort to define a clinical algorithm for controlling serum calcium levels post-operatively.
- The fall and rise of parathyroidectomy in U.S. hemodialysis patients, 1992 to 2002Robert N Foley
Chronic Disease Research Group, Minneapolis Medical Research Foundation, MN 55404, USA
J Am Soc Nephrol 16:210-8. 2005..the therapeutic approach to managing hyperparathyroidism has changed dramatically, it is unknown whether parathyroidectomy rates continue to decline in the United States...
- Minimally invasive video-assisted parathyroidectomy (MIVAP) for secondary hyperparathyroidism: report of initial experiencePiero F Alesina
Klinik für Chirurgie und Zentrum für Minimal Invasive Chirurgie, Kliniken Essen Mitte, Akademisches Lehrkrankenhaus der Universität Duisburg Essen, Essen, Germany
Am J Surg 199:851-5. 2010Minimally invasive video-assisted parathyroidectomy (MIVAP) has become a well-accepted procedure for patients with primary hyperparathyroidism...
- Intraoperative laryngeal nerve monitoring during thyroidectomy and parathyroidectomy: A prospective studyN Julien
Service d ORL et de Chirurgie Cervico faciale, Hopital Beaujon, AP HP, 100 Boulevard du General Leclerc, Clichy, France Clinique Bizet, 21 rue Georges Bizet, Paris, France
Eur Ann Otorhinolaryngol Head Neck Dis 129:69-76. 2012The aim of this study was to stimulate the recurrent laryngeal nerve during thyroidectomy or parathyroidectomy and to record the muscle responses in an attempt to predict postoperative vocal fold mobility.
- Improved long-term survival of dialysis patients after near-total parathyroidectomyJyotirmay Sharma
Department of Surgery, Emory University, Atlanta, GA 30322, USA
J Am Coll Surg 214:400-7; discussion 407-8. 2012..The aim of this study was to compare short- and long-term mortality in dialysis patients who underwent near-total parathyroidectomy (NTPTX) and matched nonoperated controls.
- How does the operative strategy for primary hyperparathyroidism impact the findings and cure rate? A comparison of 800 parathyroidectomiesJulie McGill
Department of Surgery, Division of Gastrointestinal and Endocrine Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA
J Am Coll Surg 207:246-9. 2008We hypothesized that a higher frequency of multigland disease and higher cure rate would result if routine four-gland exploration (4GL) was used as compared with focused parathyroidectomy (FP) for treatment of primary hyperparathyroidism.
- Mild primary hyperparathyroidism: vitamin D deficiency and cardiovascular risk markersParastou Farahnak
Section of Surgery, Department of Clinical Science and Education, Karolinska Institutet, Sodersjukhuset, Stockholm, Sweden
J Clin Endocrinol Metab 96:2112-8. 2011..The extent and clinical significance of cardiovascular (CV) abnormalities associated with mild primary hyperparathyroidism (PHPT) are still matters for discussion...
- Radioguided parathyroidectomy is equally effective for both adenomatous and hyperplastic glandsHerbert Chen
University of Wisconsin Medical School Department of Surgery, H4 750 CSC 600 Highland Avenue, Madison, WI, USA
Ann Surg 238:332-7; discussion 337-8. 2003To determine the utility of radioguided parathyroidectomy for patients with hyperparathyroidism, we studied the properties of 180 resected, hyperfunctioning parathyroid glands.
- Association between increased serum osteoprotegerin levels and improvement in bone mineral density after parathyroidectomy in hemodialysis patientsCai Mei Zheng
Division of Nephrology, Department of Medicine, Taipei Medical University Shuang Ho Hospital, Taipei Medical University, Taipei, Taiwan
Tohoku J Exp Med 226:19-27. 2012..HD patients with refractory SHPT can benefit from parathyroidectomy (PTX) treatment, but the changes of serum OPG, bone turnover markers and bone mineral density (BMD) ..
- Bone formation by minimodeling is more active than remodeling after parathyroidectomyAiji Yajima
Department of Nephrology, Towa Hospital, Adachi ku, Tokyo, Japan
Kidney Int 74:775-81. 2008..In patients undergoing parathyroidectomy for secondary hyperparathyroidism, we compared the contribution of minimodeling to remodeling during the ..
- [Radio-guided parathyroidectomy: successful intraoperative parathyroid localization diagnosis with 99mTc-sestamibi in primary and recurrent hyperparathyroidism]B Geissler
, Klinikum Augsburg
Chirurg 72:1179-85. 2001..0 to 1.2 in undetected adenomas. In 67% of these patients we performed a minimally invasive open parathyroidectomy. In two cases of recurrent HPT the scan-guided detection of ectopic parathyroid tissue was efficient...
- Non-Classical Manifestations of Primary HyperparathyroidismShonni J Silverberg; Fiscal Year: 2013..in cardiovascular structure or function in patients with asymptomatic PHPT are reversible after parathyroidectomy. SA2b...
- Skeletal Regulation of Cortical and Trabecular Bone by Parathyroid HormoneNatalie Cusano; Fiscal Year: 2013..or HypoPT before and after correction of the abnormal PTH state, either by normalization of PTH levels by parathyroidectomy (PHPT) or by administration of PTH (HypoPT)...
- GENETIC LINKAGE MAPPING OF FAMILIAL BENIGN HYPERCALCEMIAHunter Heath; Fiscal Year: 1991..Subtotal parathyroidectomy does not mitigate the biochemical abnormalities...
- REGULATION OF PARATHYROID HORMONE AND CALCITONIN GENESJustin Silver; Fiscal Year: 1991..iii) After unilateral parathyroidectomy there is marked compensatory hyperplasia of the contralateral parathyroid...
- DISORDERS OF MINERAL METABOLISM IN CHILDRENThomas Carpenter; Fiscal Year: 2003..study indicated successful suppression of autonomous hyperparathyroidism in 4 XLH patients considered for parathyroidectomy. Thus, a controlled trial evaluating efficacy and safety of 24,25(OH)2D3 in the management of autonomous ..
- INTERACTION OF ORAL CALCIUM WITH POTASSIUM IN HYPERTENSIJACOB PEULER; Fiscal Year: 1999..1,25D protects arteries from loss of EC relaxing activity during sustained culture in 1.25D free medium. Parathyroidectomy, which markedly lowers 1,25D, impairs arterial EC relaxing activity in hypertensive rats...
- SPECIALIZED CENTER OF RESEARCH IN OSTEOPOROSISRobert Lindsay; Fiscal Year: 2002..in post-menopausal women to characterize the effects of chronically increased PTH, and its reduction (after parathyroidectomy) on skeletal homeostasis...
- Regulating Neuroendocrine Phenotype in CancerHerbert Chen; Fiscal Year: 2010..Furthermore, these finding may permit development of components of raf-1 pathway as therapeutic targets in the treatment and palliation of NE tumors. ..
- Phase II Clinical Trial Utilizing Lithium for Patients with Neuroendocrine TumorsHerbert Chen; Fiscal Year: 2008..Besides surgery, there are limited curative and palliative treatments available to patients with metastatic NE tumors, emphasizing the need for development of other forms of therapy. [unreadable] [unreadable] [unreadable]..
- Novel Signaling Targets in GI Neuroendocrine TumorsHerbert Chen; Fiscal Year: 2005..The possibility that raf-l-mediated hormone suppression could be induced by a soluble factor would provide a plausible, therapeutic delivery method. ..
- Signaling Pathways in Medullary Thyroid CancerHerbert Chen; Fiscal Year: 2004..abstract_text> ..
- PRIMARY HYPERPARATHYROIDISM: NON-CLASSICAL MANIFESTATIONSShonni Silverberg; Fiscal Year: 2009..abstract_text> ..
- Developing Biomarker-Based Prognostics In Breast CancerJohn Olson; Fiscal Year: 2008..abstract_text> ..
- Improving genomic prediction models in breast cancerJohn Olson; Fiscal Year: 2005....
- Targeting Bone Remodeling For the Treatment of OsteoporosisJohn Bilezikian; Fiscal Year: 2008..The purpose of this meeting is to bring together experts from these interdisciplinary fields so as to define the direction of the future. ..
- Extracellular matrix and protease markers of malignant thyroid neoplasmElectron Kebebew; Fiscal Year: 2007..We will use these results to design a multicenter clinical trial evaluating the diagnostic and prognostic value of ECM1 and TMPRSS4 expression in patients with thyroid neoplasm. [unreadable] [unreadable] [unreadable]..
- The long-term consequences of postoperative acute kidney injuryAreef Ishani; Fiscal Year: 2008..Once the AKI- associated burden of CKD has been precisely estimated and modifiable factors have been identified, clinical trials can be performed that may reduce this disease burden. [unreadable] [unreadable] [unreadable]..
- EARLY HUSBANDRY INFLUENCES ON ADULT PHENOTYPEMICHAEL TORDOFF; Fiscal Year: 2009..The results will lead to better environmental controls in future work and, asa direct consequence, easierand more rapid progress with genetic analyses. ..
- Pharmacokinetics & Genomics in Glomerular DiseasesMELANIE JOY; Fiscal Year: 2008..The selection of collaborators with expertise in the areas of this grant will enhance the career development of Dr. Joy. ..
- Regulation of SMAD4 and BMPR1A Expression in Juvenile PolyposisJames R Howe; Fiscal Year: 2010..abstract_text> ..
- DIURNAL AND PULSATILE PTH SECRETION IN RENAL FAILUREWilliam Goodman; Fiscal Year: 2001....
- Mineral Metabolism and Cardiovascular Risk among Older AdultsBryan Kestenbaum; Fiscal Year: 2009..Proposed analyses aim to clarify the roles of individual mineral markers with respect to CV health among older adults and to pave the way for future trials that target these markers as a means to improve CV outcomes. ..
- REGULATION OF BONE TURNOVER IN RENAL OSTEODYSTROPHYM Langub; Fiscal Year: 2003..Altogether, the study and training will foster long term scientific productivity in the trainee's chosen field of bone pathology and biology. ..
- Cardiac Outcomes Associated with Renal OsteodystrophyBryan Kestenbaum; Fiscal Year: 2007..The proposed study aims to shed light on the relationship between a common renal related metabolic disorder and the epidemic burden of CVD found among this patient population. ..
- Tools for mapping transcriptional networksUri Alon; Fiscal Year: 2006..We expect that the analysis tools and concepts developed in E. coli will be very useful in mapping complex regulatory circuits in other cell types. [unreadable] [unreadable]..
- Influence of Tumor Immunogenicity to ImmunotherapyJeffrey Norton; Fiscal Year: 2006..unreadable] [unreadable]..
- Biology of Headpin (a novel serpin) in Oral CancerGary Clayman; Fiscal Year: 2006..Progress in this area could lead to development of new molecular based targets for the management of oral cancer. ..
- The Molecular Basis of Juvenile PolyposisJames Howe; Fiscal Year: 2005..These studies will also benefit JP patients by improving presymptomatic genetic testing, and identification of new therapeutic targets for polyp regression and cancer prevention in JP. ..
- Coronary calcification in hemodialysis patientsWilliam Goodman; Fiscal Year: 2005....
- PET Imaging of the Pancreas in Murine Models of DiabetesPaige Clark; Fiscal Year: 2005..The method could also be useful in evaluating the function of pancreatic transplants and successful engraftment of transplanted progenitor or beta cells. ..
- Molecular Mechanisms of Ectopic Bone FormationSTEVEN LIETMAN; Fiscal Year: 2006..abstract_text> ..