Genomes and Genes
Summary: The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.
Articles from Journal RESEARCH
Articles from Journal RESEARCH1
Publications323 found, 100 shown here
- Preoperative biliary drainage for cancer of the head of the pancreasNiels A van der Gaag
Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
N Engl J Med 362:129-37. 2010..The benefits of preoperative biliary drainage, which was introduced to improve the postoperative outcome in patients with obstructive jaundice caused by a tumor of the pancreatic head, are unclear...
- Pancreatogastrostomy with gastric partition after pylorus-preserving pancreatoduodenectomy versus conventional pancreatojejunostomy: a prospective randomized studyLaureano Fernandez-Cruz
ICMDM Department of Surgery, Hospital Clinic de Barcelona, Barcelona, Spain
Ann Surg 248:930-8. 2008..the results of postoperative morbidity rate of a new pancreatogastrostomy technique, pylorus-preserving pancreaticoduodenectomy (PPPD) with gastric partition (PPPD-GP) with the conventional technique of pancreaticojejunostomy (PJ).
- One thousand consecutive pancreaticoduodenectomiesJohn L Cameron
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
Ann Surg 244:10-5. 2006To trace the evolution of pancreaticoduodenectomy from the decade of the 1960s through the first decade of the new Millenium, through the experience of one surgeon doing 1000 consecutive operations.
- Reconstruction by pancreaticojejunostomy versus pancreaticogastrostomy following pancreatectomy: results of a comparative studyClaudio Bassi
Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, Hospital G B Rossi, University of Verona, 37134 Verona, Italy
Ann Surg 242:767-71, discussion 771-3. 2005To compare the results of pancreaticogastrostomy versus pancreaticojejunostomy following pancreaticoduodenectomy in a prospective and randomized setting.
- Conventional versus binding pancreaticojejunostomy after pancreaticoduodenectomy: a prospective randomized trialShu You Peng
General Surgery Department, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jie Fang Road, Hangzhou 310009, China
Ann Surg 245:692-8. 2007This study compared the postoperative pancreatic anastomosis leakage rate of a new binding technique with the conventional technique of pancreaticojejunostomy after pancreaticoduodenectomy.
- Most pancreatic cancer resections are R1 resectionsIrene Esposito
Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 220, 69120 Heidelberg, Germany
Ann Surg Oncol 15:1651-60. 2008..Although general guidelines for the processing of pancreatic specimens have been established, there is currently no widely accepted standardized protocol for pathological examination, especially with respect to resection margins...
- Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trialClaudio Bassi
Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, Hospital G B Rossi University of Verona, Piazzale L A Scuro, 37134 Verona, Italy
Surgery 134:766-71. 2003Anastomotic failure is still a significant problem that affects the outcome of pancreaticoduodenectomy. There have been many techniques proposed for the reconstruction of pancreatic digestive continuity, but there have been few ..
- Pancreaticoduodenectomy with vascular resection for local advanced pancreatic head cancer: a single center retrospective studyChunyou Wang
Pancreatic Center, Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Ave 1277, Wuhan City, Hubei Province, 430022, China
J Gastrointest Surg 12:2183-90. 2008b>Pancreaticoduodenectomy with vascular resection remains a controversial approach for patients with local advanced pancreatic head cancer for the lack of evidences of survival and quality of life benefits...
- Binding pancreaticojejunostomy is a new technique to minimize leakageShuyou Peng
Department of Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Province, People s Republic of, 310009, Hangzhou, China
Am J Surg 183:283-5. 2002b>Pancreaticoduodenectomy (Whipple procedure) has been the standard treatment for periampullary and pancreatic carcinoma...
- Pylorus ring resection reduces delayed gastric emptying in patients undergoing pancreatoduodenectomy: a prospective, randomized, controlled trial of pylorus-resecting versus pylorus-preserving pancreatoduodenectomyManabu Kawai
Second Department of Surgery, Wakayama Medical University School of Medicine, Wakayama, Japan
Ann Surg 253:495-501. 2011....
- Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma, part 2: randomized controlled trial evaluating survival, morbidity, and mortalityCharles J Yeo
Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
Ann Surg 236:355-66; discussion 366-8. 2002To evaluate, in a prospective, randomized single-institution trial, the end points of operative morbidity, operative mortality, and survival in patients undergoing standard versus radical (extended) pancreaticoduodenectomy.
- Laparoscopic pancreaticoduodenectomy: technique and outcomesChinnasamy Palanivelu
Department of Gastrointestinal and Minimally Invasive Surgery, GEM Hospital, Coimbatore, India
J Am Coll Surg 205:222-30. 2007We describe our experience with laparoscopic pancreaticoduodenectomy, including 5-year actuarial survival rates.
- Pancreaticoduodenectomy with vascular resection: margin status and survival durationJennifer F Tseng
Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
J Gastrointest Surg 8:935-49; discussion 949-50. 2004Major vascular resection performed at the time of pancreaticoduodenectomy (PD) for adenocarcinoma remains controversial...
- Laparoscopic pancreaticoduodenectomy for benign and malignant diseasesJ L Dulucq
Department of Abdominal Surgery, ILS, Maison de Santé Protestante, Bagatelle, MSPB, Route de Toulouse 203, 33401, Talence Bordeaux, France
Surg Endosc 20:1045-50. 2006..To the best of the authors' knowledge, their series of laparoscopic pancreatoduodenectomies is the largest reported to date...
- Defining morbidity after pancreaticoduodenectomy: use of a prospective complication grading systemStephen R Grobmyer
Gastric and Mixed Tumor Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
J Am Coll Surg 204:356-64. 2007..Improving surgical quality of care requires accurate reporting of postoperative complications...
- Complications after pancreatoduodenectomy: imaging and imaging-guided interventional proceduresD A Gervais
Department of Radiology, Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
Radiographics 21:673-90. 2001....
- Laparoscopic pancreatoduodenectomy: a review of 285 published casesAndrew A Gumbs
Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
Ann Surg Oncol 18:1335-41. 2011..As the technique becomes more diffuse, issues regarding the adequacy of oncologic margins and lymph node retrieval need to be addressed...
- Serum CA 19-9 as a marker of resectability and survival in patients with potentially resectable pancreatic cancer treated with neoadjuvant chemoradiationMatthew H G Katz
Department of Surgery, The University of California, Orange, CA, USA
Ann Surg Oncol 17:1794-801. 2010..We evaluated CA 19-9 as a marker of therapeutic response, completion of therapy, and survival in patients enrolled on two recently reported clinical trials...
- A surgical and pathological based classification of resective treatment of pancreatic cancer. Summary of an international workshop on surgical procedures in pancreatic cancerS Pedrazzoli
Dipartimento di Scienze Mediche e Chirurgiche, Semeiotica Chirurgica, University of Padova, Italy
Dig Surg 16:337-45. 1999..The extent of pancreatic resection and lymphadenectomy, both for Kausch-Whipple pancreatoduodenectomy and for left pancreatectomy, is variable between surgeons, according to their training...
- Can laparoscopic pancreaticoduodenectomy be safely implemented?Amer H Zureikat
Department of Surgery, Division of Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
J Gastrointest Surg 15:1151-7. 2011The implementation of laparoscopic pancreaticoduodenectomy (LPD) has been appropriately met with apprehension, and concerns exist regarding outcomes early in a program's experience. We reviewed our early experience and outcomes of LPD.
- External pancreatic duct stent decreases pancreatic fistula rate after pancreaticoduodenectomy: prospective multicenter randomized trialPatrick Pessaux
Pôle des Pathologies Digestives, Hépatiques et de la Transplantation, Hopital de Hautepierre, Universite de Strasbourg, France
Ann Surg 253:879-85. 2011Pancreatic fistula (PF) is a leading cause of morbidity and mortality after pancreaticoduodenectomy (PD)...
- Fatty pancreas and increased body mass index are risk factors of pancreatic fistula after pancreaticoduodenectomySebastien Gaujoux
Department of Hepato pancreato biliary Surgery, Pôle des Maladies de l Appareil Digestif PMAD, Paris, France
Surgery 148:15-23. 2010..Pancreatic fistula (PF) after pancreatoduodenectomy (PD) remains a challenging problem. The only commonly accepted risk factor is the soft consistency of the pancreatic remnant...
- Pancreaticogastrostomy decreased relaparotomy caused by pancreatic fistula after pancreaticoduodenectomy compared with pancreaticojejunostomyElie Oussoultzoglou
Centre de Chirurgie Viscerale et de Transplantation, Hôpital Universitaire de Hautepierre, Strasbourg, Strasbourg Cedex, France
Arch Surg 139:327-35. 2004Pancreaticogastrostomy (PG) is associated with a lower relaparotomy rate following pancreaticoduodenectomy (PD) than pancreaticojejunostomy (PJ).
- Does pancreatic duct stenting decrease the rate of pancreatic fistula following pancreaticoduodenectomy? Results of a prospective randomized trialJordan M Winter
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Gastrointest Surg 10:1280-90; discussion 1290. 2006..duct stenting remains an attractive strategy to reduce the incidence of pancreatic fistulas following pancreaticoduodenectomy (PD) with encouraging results in both retrospective and prospective studies...
- Risk of malignancy in resected cystic tumors of the pancreas < or =3 cm in size: is it safe to observe asymptomatic patients? A multi-institutional reportC J Lee
University of Michigan Medical Center, Ann Arbor, MI 48109, USA
J Gastrointest Surg 12:234-42. 2008..3%. This study suggests that a group of patients with small cystic pancreatic neoplasms who have low risk of malignancy can be identified, and selective resection of these lesions may be appropriate...
- Pancreatic anastomoses after pancreaticoduodenectomy: do we need further studies?Shailesh V Shrikhande
Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Dr Ernest Borges Marg, Parel, Mumbai, 400 012, India
World J Surg 29:1642-9. 2005..the single most important factor responsible for the considerable morbidity and mortality associated with pancreaticoduodenectomy. Management of the pancreatic remnant is controversially discussed, reflecting the complexity of ..
- Assessment of complications after pancreatic surgery: A novel grading system applied to 633 patients undergoing pancreaticoduodenectomyMichelle L DeOliveira
Swiss HPB Hepato Pancreato Biliary Center, Department of Visceral and Transplantation Surgery, Zurich University Hospital, Zurich, Switzerland
Ann Surg 244:931-7; discussion 937-9. 2006To define a simple and reproducible classification of complications following pancreaticoduodenectomy (PD) based on a therapy-oriented severity grading system.
- External drainage of pancreatic duct with a stent to reduce leakage rate of pancreaticojejunostomy after pancreaticoduodenectomy: a prospective randomized trialRonnie T P Poon
Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
Ann Surg 246:425-33; discussion 433-5. 2007Pancreatic fistula is a leading cause of morbidity and mortality after pancreaticoduodenectomy. External drainage of pancreatic duct with a stent has been shown to reduce pancreatic fistula rate of pancreaticojejunostomy in a few ..
- Risk factors of pancreatic leakage after pancreaticoduodenectomyYin Mo Yang
Department of Surgery, The First Teaching Hospital, Health Science Center, Beijing University, Beijing 100034, China
World J Gastroenterol 11:2456-61. 2005To analyze the risk factors for pancreatic leakage after pancreaticoduodenectomy (PD) and to evaluate whether duct-to-mucosa pancreaticojejunostomy could reduce the risk of pancreatic leakage.
- Pylorus preserving pancreaticoduodenectomy versus standard Whipple procedure: a prospective, randomized, multicenter analysis of 170 patients with pancreatic and periampullary tumorsKhe T C Tran
Department of General Surgery, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
Ann Surg 240:738-45. 2004..randomized multicenter study was performed to assess whether the results of pylorus-preserving pancreaticoduodenectomy (PPPD) equal those of the standard Whipple (SW) operation, especially with respect to duration of surgery,..
- Total laparoscopic pancreaticoduodenectomy: feasibility and outcome in an early experienceMichael L Kendrick
Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Arch Surg 145:19-23. 2010Total laparoscopic pancreaticoduodenectomy is a safe and effective therapeutic approach.
- Preoperative CA19-9 levels and lymph node ratio are independent predictors of survival in patients with resected pancreatic ductal adenocarcinomaR A Smith
Division of Surgery and Oncology, School of Cancer Studies, University of Liverpool, Liverpool, UK
Dig Surg 25:226-32. 2008....
- Pylorus-preserving pancreaticoduodenectomy versus conventional pancreaticoduodenectomy for pancreatic adenocarcinomaMasaji Tani
Second Department of Surgery, Wakayama Medical University, School of Medicine, 811 1 Kimiidera, Wakayama, 641 8510, Japan
Surg Today 39:219-24. 2009A few randomized controlled trials have questioned the justification of pylorus-preserving pancreaticoduodenectomy (PpPD) for pancreatic cancer and periampullary cancer...
- Laparoscopic robotic-assisted pancreaticoduodenectomy: a case-matched comparison with open resectionS Chalikonda
Department of General Surgery, Cleveland Clinic Foundation, A100, 9500 Euclid Avenue A100, Cleveland, OH 44195, USA
Surg Endosc 26:2397-402. 2012Minimally invasive procedures have expanded recently to include pancreaticoduodenectomy (PD), but the efficacy of a laparoscopic robotic-assisted approach has not been demonstrated...
- Effect of neoadjuvant chemoradiation on operative mortality and morbidity for pancreaticoduodenectomyTsung Yen Cheng
Department of Surgery, Duke University Medical Center, Box 3118, Durham, North Carolina 27710, USA
Ann Surg Oncol 13:66-74. 2006Neoadjuvant chemoradiotherapy (neo-CRT) is being used with increasing frequency for periampullary tumors, but how it alters the complication rate of pancreaticoduodenectomy (PD) is unclear.
- Early versus late drain removal after standard pancreatic resections: results of a prospective randomized trialClaudio Bassi
Department of Surgery, G B Rossi Hospital, University of Verona, Verona, Italy
Ann Surg 252:207-14. 2010..The role of surgically placed intra-abdominal drainages after pancreatic resections has not been clearly established. In particular, their effect on morbidity rates and the optimal timing for their removal remains controversial...
- Subtotal stomach-preserving pancreaticoduodenectomy (SSPPD) prevents postoperative delayed gastric emptyingHiroshi Kurahara
Department of Surgical Oncology and Digestive Surgery, Graduate School of Medical Sciences, Kagoshima University, Japan
J Surg Oncol 102:615-9. 2010Delayed gastric emptying (DGE) is one of main complications after pylorus-preserving pancreaticoduodenectomy (PPPD) with regional lymph node dissection (RLND)...
- Randomized clinical trial to assess the efficacy of ulinastatin for postoperative pancreatitis following pancreaticoduodenectomyKenichiro Uemura
Department of Surgery, Graduate School of Biochemical Sciences, Hiroshima University, Hiroshima, Japan
J Surg Oncol 98:309-13. 2008..The aim of this study was to assess the efficacy of ulinastatin for postoperative pancreatitis following pancreaticoduodenectomy in a randomized clinical trial.
- Prognostic relevance of lymph node ratio following pancreaticoduodenectomy for pancreatic cancerTimothy M Pawlik
Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD 22187 6681, USA
Surgery 141:610-8. 2007..investigated the ratio of the number of lymph nodes harboring metastatic cancer to the total number of lymph nodes examined (lymph node ratio [LNR]) with regard to outcome after pancreaticoduodenectomy for ductal cancer of the pancreas.
- Pancreaticoduodenectomy for pancreatic head cancer: PPPD versus Whipple procedurePin Wen Lin
Department of Surgery, Institute of Clinical Medicine, School of Medicine National Cheng Kung University, Tainan, Taiwan
Hepatogastroenterology 52:1601-4. 2005Resectable carcinoma of the head of the pancreas can be treated with either standard (the Whipple) or pylorus-preserving pancreaticoduodenectomy (PPPD). Only a few reports compared the differences between these two procedures.
- Survival after pancreaticoduodenectomy is not improved by extending resections to achieve negative marginsJonathan Hernandez
Center for Digestive Disorders, Department of Surgery, University of South Florida, Tampa General Hospital, Tampa, Florida 33601, USA
Ann Surg 250:76-80. 2009..This study was undertaken to determine the survival benefit of extending resections to obtain microscopically negative margins after positive intraoperative frozen sections...
- Current status of robot-assisted laparoscopic pancreaticoduodenectomy and distal pancreatectomy: a comprehensive reviewEric C H Lai
Department of Surgery, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China
Asian J Endosc Surg 6:158-64. 2013This article reviews the current status of robot-assisted laparoscopic pancreaticoduodenectomy and distal pancreatectomy.
- Chronic pancreatitis: early results of pancreatoduodenectomy and analysis of risk factorsFelix Ruckert
Department of General, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany
Pancreas 40:925-30. 2011....
- Robot-assisted laparoscopic pancreaticoduodenectomy versus open pancreaticoduodenectomy--a comparative studyEric C H Lai
Department of Surgery, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong SAR, China
Int J Surg 10:475-9. 2012..The recently developed robotic technology allows surgeons to perform pancreaticoduodenectomy. A comparative study was undertaken to study outcomes between robotic approach and open approach.
- Clinical significance of pathologic subtype in curatively resected ampulla of vater cancerWoo Seok Kim
Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
J Surg Oncol 105:266-72. 2012..The aims of this study were to identify those factors that affect recurrence after curative resection and to investigate differences between the clinicopathologic features of these two pathologic subtypes...
- Preoperative serum C-reactive protein levels and post-operative lymph node ratio are important predictors of survival after pancreaticoduodenectomy for pancreatic ductal adenocarcinomaPandanaboyana Sanjay
Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom
JOP 13:199-204. 2012..There is paucity of data on the prognostic value of pre-operative inflammatory response and post-operative lymph node ratio on patient survival after pancreatic-head resection for pancreatic ductal adenocarcinoma...
- Quality of life in patients after pancreaticoduodenectomy for chronic pancreatitisFelix Ruckert
Department of General, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
J Gastrointest Surg 15:1143-50. 2011b>Pancreaticoduodenectomy (PD) is the most frequently performed resectional procedure in chronic pancreatitis. Only a few studies have evaluated quality of life (QOL) after PD for chronic pancreatitis...
- Perineural and intraneural invasion in posttherapy pancreaticoduodenectomy specimens predicts poor prognosis in patients with pancreatic ductal adenocarcinomaDeyali Chatterjee
Departments of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
Am J Surg Pathol 36:409-17. 2012..However, the prognostic significance of PNI in patients with PDAC who received neoadjuvant therapy and pancreaticoduodenectomy is not clear...
- Laparoscopic vs open pancreaticoduodenectomy: overall outcomes and severity of complications using the Accordion Severity Grading SystemHoracio J Asbun
Department of General Surgery, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USA
J Am Coll Surg 215:810-9. 2012Minimal access surgery techniques have evolved to include complex surgical procedures. Laparoscopic pancreaticoduodenectomy (LPD) is a complex operation that pancreas surgeons have been slow to adopt...
- Evolution of the Whipple procedure at the Massachusetts General HospitalCarlos Fernandez-del Castillo
Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
Surgery 152:S56-63. 2012..The goal of this study was to investigate the evolution of pancreatoduodenectomy at the Massachusetts General Hospital (MGH)...
- Robotic versus open pancreaticoduodenectomy: a comparative study at a single institutionNicolas Christian Buchs
Division of General, Minimally Invasive and Robotic Surgery, Department of Surgery, University of Illinois at Chicago, 840 S Wood Street, Suite 435 E, Chicago, IL 60612, USA
World J Surg 35:2739-46. 2011Minimally invasive pancreaticoduodenectomy (PD) remains one of the most challenging abdominal procedures, and its application is poorly reported in the literature so far...
- A prospective randomized trial comparing standard pancreatoduodenectomy with pancreatoduodenectomy with extended lymphadenectomy in resectable pancreatic head adenocarcinomaMichael B Farnell
Mayo Clinic, Rochester, Minnesota 55905, USA
Surgery 138:618-28; discussion 628-30. 2005..To compare operative morbidity, mortality, quality of life, and survival after pancreatoduodenectomy (PD) versus pancreatoduodenectomy with extended lymphadenectomy (PD/ELND) in patients with resectable pancreatic cancer...
- A systematic review and meta-analysis of pylorus-preserving versus classical pancreaticoduodenectomy for surgical treatment of periampullary and pancreatic carcinomaMarkus K Diener
University of Heidelberg, Department of General, Visceral and Trauma Surgery, Heidelberg, Germany
Ann Surg 245:187-200. 2007Comparison of effectiveness between the pylorus-preserving pancreaticoduodenectomy ("pylorus-preserving Whipple" [PPW]) and the classic Whipple (CW) procedure.
- Laparoscopic pancreaticoduodenectomy: a retrospective review of 19 casesRaffaele Pugliese
Department of Surgery, Niguarda Hospital, Milan, Italy
Surg Laparosc Endosc Percutan Tech 18:13-8. 2008..This study was designed to assess the feasibility and results of laparoscopic pancreaticoduodenectomy for neoplasms of the pancreatic head, analyzing steps of learning curve, conversion rate, and short-term ..
- Low-dose erythromycin reduces delayed gastric emptying and improves gastric motility after Billroth I pylorus-preserving pancreaticoduodenectomyS Ohwada
Second Department of Surgery, Gunma University Faculty of Medicine, Maebashi, Japan
Ann Surg 234:668-74. 2001..that early and low doses of erythromycin reduce the incidence of early delayed gastric emptying (DGE) and induce phase 3 of the migratory motor complex in the stomach after Billroth I pylorus-preserving pancreaticoduodenectomy (PPPD).
- Clinical and economic validation of the International Study Group of Pancreatic Fistula (ISGPF) classification schemeWande B Pratt
Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
Ann Surg 245:443-51. 2007The authors sought to validate the ISGPF classification scheme in a large cohort of patients following pancreaticoduodenectomy (PD) in a pancreaticobiliary surgical specialty unit.
- Prevention and management of pancreatic fistulaMark P Callery
Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, ST 9, Boston, MA 02215, USA
J Gastrointest Surg 13:163-73. 2009..Key citations from the past seventeen years have been scrutinized, and together with personal experience, provide the basis for this review...
- Risk factors of pancreatic fistula and delayed gastric emptying after pancreaticoduodenectomy with pancreaticogastrostomyEmilie Lermite
Department of Digestive Surgery, University Hospital, Angers, France
J Am Coll Surg 204:588-96. 2007..gastric emptying (DGE) are, respectively, the most frightening and most frequent complications after pancreaticoduodenectomy (PD)...
- Development of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) after pancreaticoduodenectomy: proposal of a postoperative NAFLD scoring systemHiroyuki Kato
Department of Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Mie, 514 8507, Japan
J Hepatobiliary Pancreat Sci 17:296-304. 2010The main etiology of NAFLD and NASH after pancreatic resection is still unclear, and the therapeutic strategy has yet to be established. The focus of this review is how predict and prevent NAFLD/NASH after pancreaticoduodenectomy.
- Survival analysis after pancreatic resection for ampullary and pancreatic head carcinoma: an analysis of clinicopathological factorsC A M Sommerville
Division of Surgery and Cancer, HPB Unit, Hammersmith Hospital, Imperial College, London, England
J Surg Oncol 100:651-6. 2009Surgery remains the only curative option for the treatment of pancreatic and ampullary carcinomas. To examine the survival differences between ampullary and pancreatic head carcinomas after pancreaticoduodenectomy.
- Diagnostic ascertainment of suspicious pancreatic mass: a threshold analysisAmnon Sonnenberg
Portland VA Medical Center, Portland, Oregon 97239, USA
Clin Gastroenterol Hepatol 6:1162-6. 2008..It is frequently difficult to differentiate between a benign and malignant pancreatic mass. The aim of this study was to assess the parameters that affect the decision to perform surgery on a suspicious pancreatic head lesion...
- Very high serum CA 19-9 levels: a contraindication to pancreaticoduodenectomy?O Turrini
Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
J Gastrointest Surg 13:1791-7. 2009..To assess the outcome of patients with resectable pancreatic adenocarcinoma (PA) associated with high serum CA 19-9 levels...
- Conservative management of pancreatic fistula after pancreaticoduodenectomy with pancreaticogastrostomyNicolas Munoz-Bongrand
Department of Digestive Surgery, Hopital Beaujon, AP HP, University Paris VII, Clichy, France
J Am Coll Surg 199:198-203. 2004Pancreatic fistula (PF), which is a major complication of pancreaticoduodenectomy (PD), can be treated conservatively or by reoperation...
- A simple scoring system based on clinical factors related to pancreatic texture predicts postoperative pancreatic fistula preoperativelyUlrich Friedrich Wellner
Department of General and Visceral Surgery Institute of Pathology, University Hospital Freiburg, Freiburg, Germany
HPB (Oxford) 12:696-702. 2010..Postoperative pancreatic fistula (POPF) is regarded as the most serious complication of pancreatic surgery. The preoperative risk stratification of patients by simple means is of interest in perioperative clinical management...
- Decreasing the pancreatic leak rate after pancreaticoduodenectomyRonnie T P Poon
Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
Adv Surg 42:33-48. 2008Although pancreaticoduodenectomy has become a safe and effective procedure for benign and malignant pancreatic diseases in recent years, leakage of pancreaticoenteric anastomosis still remains a major cause of morbidity and even ..
- Large-cell neuroendocrine carcinoma of the ampulla of VaterZ Stojsic
Institute of Pathology, School of Medicine, University of Belgrade, Dr Subotica 1 II, 11000, Belgrade, Serbia
Med Oncol 27:1144-8. 2010..3 and 61%, respectively. Two months after surgery, liver metastases occurred, confirming highly aggressive behavior of large-cell neuroendocrine carcinoma...
- Endovascular management of hepatic artery pseudoaneurysm hemorrhage complicating pancreaticoduodenectomyJohn Harvey
Vascular Surgery Service, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
J Vasc Surg 43:613-7. 2006Gastrointestinal bleeding is a morbid complication of pancreaticoduodenectomy. Determining its etiology is often a daunting challenge in that both common and unusual mechanisms may be operative...
- Delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy: validation of International Study Group of Pancreatic Surgery classification and analysis of risk factorsGiuseppe Malleo
Department of Surgery, General Surgery B Unit, G B Rossi Hospital, University of Verona, Verona, Italy
HPB (Oxford) 12:610-8. 2010..study evaluates the incidence and clinical features and associated risk factors of delayed gastric emptying (DGE) after pancreaticoduodenectomy, employing the International Study Group of Pancreatic Surgery (ISGPS) consensus definition.
- Pancreaticoduodenectomy: role of interventional radiologists in managing patients and complicationsTaylor A Sohn
Department of Surgery, The Johns Hopkins Medical Institutions, 600 North Wolfe Street, Blalock 606, Baltimore, MD 21287 4606, USA
J Gastrointest Surg 7:209-19. 2003Although the mortality rate after pancreaticoduodenectomy has decreased, the morbidity rate remains high. Major morbidity is often managed with the aid of interventional radiologists...
- Evaluation of the International Study Group of Pancreatic Surgery definition of delayed gastric emptying after pancreatoduodenectomy in a high-volume centreT Welsch
Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, Heidelberg, Germany
Br J Surg 97:1043-50. 2010..Delayed gastric emptying (DGE) is a common complication after pancreatoduodenectomy. The International Study Group of Pancreatic Surgery (ISGPS) definition of DGE has not been evaluated and validated in a high-volume centre...
- A simple and safe anastomosis in pancreaticogastrostomy using mattress suturesHiroaki Ohigashi
Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
Am J Surg 196:130-4. 2008..Postoperative amylase levels in the drainage fluid decreased significantly and none of the 17 patients developed pancreatic fistula formation. The technique is simple and shortens the time required for anastomosis...
- Does type of pancreaticojejunostomy after pancreaticoduodenectomy decrease rate of pancreatic fistula? A randomized, prospective, dual-institution trialAdam C Berger
Department of Surgery, Thomas Jefferson University, Jefferson Pancreas, Biliary and Related Cancer Center, Philadelphia, PA 19107, USA
J Am Coll Surg 208:738-47; discussion 747-9. 2009Pancreatic fistula (PF) is one of the most common complications after pancreaticoduodenectomy. There have been no large prospective randomized trials evaluating PF rates comparing invagination versus duct to mucosa pancreaticojejunostomy...
- Clinical characteristics of de novo nonalcoholic fatty liver disease following pancreaticoduodenectomyNaoki Tanaka
Department of Metabolic Regulation, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, Asahi 3 1 1, Matsumoto 390 8621, Japan
J Gastroenterol 46:758-68. 2011..We explored the clinical characteristics of newly appearing nonalcoholic fatty liver disease (NAFLD) after pancreaticoduodenectomy (PD), designated as de novo NAFLD after PD.
- Long-term pancreatic endocrine function following pancreatoduodenectomy with pancreaticogastrostomyYoshiaki Murakami
Department of Surgery, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Minami Ku, Hiroshima, Japan
J Surg Oncol 97:519-22. 2008..The aim of this study was to evaluate long-term pancreatic endocrine function following pancreatoduodenectomy with pancreaticogastrostomy...
- Omental flap in pancreaticoduodenectomy for protection of splanchnic vesselsAtsuyuki Maeda
Division of Hepato Biliary Pancreatic Surgery, Shizuoka Cancer Center Hospital, 1007 Shimo Nagakubo, 411 8777 Sunto Nagaizumi, Shizuoka, Japan
World J Surg 29:1122-6. 2005Intraabdominal bleeding, the most life-threatening complication following pancreaticoduodenectomy (PD), most often is associated with failure of a pancreaticojejunostomy anastomosis or with intraabdominal infection...
- Incidence of pancreatic anastomotic failure and delayed gastric emptying after pancreatoduodenectomy in 507 consecutive patients: use of a web-based calculator to improve homogeneity of definitionYasushi Hashimoto
Section of General, Vascular, and Thoracic Surgery, Virginia Mason Medical Center, Seattle, WA 98111, USA
Surgery 147:503-15. 2010..The solution might be to create a web-based calculator, test it for ambiguity and reliability with a large number of cases, and then make it available to the public...
- Early perioperative outcomes and pancreaticoduodenectomy in a general surgery residency training programCraig P Fischer
Department of Surgery, The Methodist Hospital, Weill Medical College of Cornell University, Houston, TX 77030, USA
J Gastrointest Surg 10:478-82. 2006..b>Pancreaticoduodenectomy (PD) is a complex procedure performed infrequently by most surgical graduates...
- Effect of hospital volume on margin status after pancreaticoduodenectomy for cancerKarl Y Bilimoria
Cancer Programs, American College of Surgeons, Chicago, IL 60611, USA
J Am Coll Surg 207:510-9. 2008..Our objective was to evaluate the effect of hospital pancreatectomy volume on margin status...
- A pancreaticoduodenectomy is acceptable for periampullary tumors in the elderly, even in patients over 80 years of ageMasaji Tani
Second Department of Surgery, Wakayama Medical University, School of Medicine, 811 1 Kimiidera, Wakayama, 641 8510, Japan
J Hepatobiliary Pancreat Surg 16:675-80. 2009Although the mortality rates for pancreaticoduodenectomy have been reported to be low for periampullary tumors at high-volume centers, postoperative results still remain unclear for elderly patients over 80 years of age.
- 1423 pancreaticoduodenectomies for pancreatic cancer: A single-institution experienceJordan M Winter
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Gastrointest Surg 10:1199-210; discussion 1210-1. 2006b>Pancreaticoduodenectomy (PD) with the possible addition of neoadjuvant or adjuvant therapy is the standard of care in the United States for adenocarcinoma originating in the pancreatic head, neck, and uncinate process...
- Outcome of pancreaticoduodenectomy and impact of adjuvant therapy for ampullary carcinomasJ H Lee
Departments of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
Int J Radiat Oncol Biol Phys 47:945-53. 2000..To determine the clinical outcomes and potential impact of adjuvant chemoradiation in patients undergoing surgical resection of ampullary carcinoma...
- Long-term results of partial pancreaticoduodenectomy for ductal adenocarcinoma of the pancreatic head: 25-year experienceAxel Richter
Department of Surgery, University Hospital Mannheim, University of Heidelberg, Theodor Kutzer Ufer, 68167, Mannheim, Germany
World J Surg 27:324-9. 2003..We concluded that surgical treatment is "as good as it gets," as extended techniques have not proved to produce better results...
- Artificial nutrition after pancreaticoduodenectomyL Gianotti
Department of Surgery, Scientific Institute San Raffaele Hospital, Milan, Italy
Pancreas 21:344-51. 2000Patients undergoing pancreaticoduodenectomy (PD) often require postoperative artificial nutrition...
- An evidence-based approach to the surgical management of resectable pancreatic adenocarcinomaAlexander Stojadinovic
Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
J Am Coll Surg 196:954-64. 2003..We conducted a comprehensive review of prospective randomized clinical trials and summarized the contemporary treatment of resectable pancreatic carcinoma...
- A comparison of pancreaticogastrostomy and pancreaticojejunostomy following pancreaticoduodenectomyGerard V Aranha
Department of Surgery and Oncology Institute, Loyola University Stritch School of Medicine, Maywood, IL, USA
J Gastrointest Surg 7:672-82. 2003..Between the years of June 1995 and June 2001, 214 patients underwent pancreaticoduodenectomy (PD) at our institution. Of these 177 had PG and 97 had pancreatojejunostomy (PJ). There were 117 (54...
- Pancreaticoduodenectomy (Whipple resections) in patients without malignancy: are they all 'chronic pancreatitis'?Susan C Abraham
Department of Pathology, Mayo Clinic, Rochester, Minnesota, 55905, USA
Am J Surg Pathol 27:110-20. 2003b>Pancreaticoduodenectomy (Whipple resection) has evolved into a safe procedure in major high-volume medical centers for the treatment of pancreatic adenocarcinoma and refractory chronic pancreatitis...
- Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma--part 3: update on 5-year survivalTaylor S Riall
Departments of Surgery, The Sol Goldman Pancreas Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
J Gastrointest Surg 9:1191-204; discussion 1204-6. 2005..update the survival analysis at the 5-year mark of patients undergoing standard versus radical (extended) pancreaticoduodenectomy (PD) for periampullary adenocarcinoma (cancers of the pancreas, ampulla, common bile duct, and duodenum)...
- Effect of preoperative biliary decompression on pancreaticoduodenectomy-associated morbidity in 300 consecutive patientsP W Pisters
Pancreatic Tumor Study Group, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4095, USA
Ann Surg 234:47-55. 2001To examine the relationship between preoperative biliary drainage and the morbidity and mortality associated with pancreaticoduodenectomy.
- Management of complications after pancreaticoduodenectomy in a high volume centre: results on 150 consecutive patientsC Bassi
Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, University of Verona, Hospital G B Rossi, Verona, Italy
Dig Surg 18:453-7; discussion 458. 2001b>Pancreaticoduodenectomy (PD) is still a difficult procedure with significant morbidity. We report 150 consecutive PDs performed during a 3-year period. All the cases have been prospectively evaluated with regard to the surgical outcome...
- Outcome after pancreaticoduodenectomy for cancer in elderly patientsRadu Scurtu
From the Centre de Chirurgie Viscérale et de Transplantation, Hopitaux Universitaires de Strasbourg, CHU Hautepierre, France
J Gastrointest Surg 10:813-22. 2006During the last decade, the outcome after pancreaticoduodenectomy (PD) for cancer showed a continuous improvement. Therefore, an increasing number of patients, especially elderly patients, have been considered for this procedure...
- [A pancreas suture-less type II binding pancreaticogastrostomy]Shu You Peng
Department of Surgery, the Sir Run Run Shaw Affiliated Hospital, Zhejiang University of Medicine, Hangzhou 310016, China
Zhonghua Wai Ke Za Zhi 47:1764-6. 2009To explore the feasibility and safety of type II binding pancreaticogastrostomy (BPG) in pancreaticoduodenectomy and mid-segmentectomy of pancreas.
- Risk factors and outcomes in postpancreaticoduodenectomy pancreaticocutaneous fistulaJohn W Lin
Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287 4606, USA
J Gastrointest Surg 8:951-9. 2004A significant fraction of patients undergoing pancreaticoduodenectomy develop a postoperative pancreaticocutaneous fistula...
- Delayed hemorrhage after pancreaticoduodenectomySeong Ho Choi
Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea South Korea
J Am Coll Surg 199:186-91. 2004Postoperative hemorrhage, particularly delayed hemorrhage after pancreaticoduodenectomy, is a serious complication and one of the most common causes of mortality after pancreaticoduodenectomy.
- Determining pattern of recurrence following pancreaticoduodenectomy and adjuvant 5-flurouracil-based chemoradiation therapy: effect of number of metastatic lymph nodes and lymph node ratioBolanle Asiyanbola
Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, Baltimore, MD 22187 6681, USA
J Gastrointest Surg 13:752-9. 2009There are limited data on patterns of recurrence and factors associated with local recurrence following pancreaticoduodenectomy for pancreatic adenocarcinoma and adjuvant 5-flurouracil-based chemoradiation therapy.
- Systematic review of minimally invasive pancreatic resectionChristopher D Briggs
Cancer Biomarkers and Prevention Group, Department of Cancer Studies and Molecular Medicine, Bio centre, University of Leicester, University Road, Leicester LE1 7RH, UK
J Gastrointest Surg 13:1129-37. 2009..This article reviews the current published literature on the safety and efficacy of minimally invasive surgery of the pancreas...
- A new technique for pancreaticogastrostomy for the soft pancreas: the transfixing suture methodHiroyuki Shinchi
Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School, 8 35 1 Sakuragaoka, Kagoshima, 890 8520, Japan
J Hepatobiliary Pancreat Surg 13:212-7. 2006Pancreatic anastomotic leakage remains a persistent problem after pancreaticoduodenectomy (PD). The presence of soft, nonfibrotic pancreatic tissue is one of the most important risk factors for pancreatic leakage...
- Prevention of pancreatic anastomotic leakage after pancreaticoduodenectomyRonnie Tung Ping Poon
Department of Surgery, Centre for Study of Liver Disease, University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Rd, Hong Kong, China
Am J Surg 183:42-52. 2002Leakage at the pancreaticoenteric anastomosis remains a common and serious complication after pancreaticoduodenectomy. Over the past decade, various measures directed towards prevention of pancreatic leakage have been studied...
- Occlusion of the pancreatic duct versus pancreaticojejunostomy: a prospective randomized trialKhe Tran
Departments of General Surgery, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
Ann Surg 236:422-8; discussion 428. 2002Using a prospective randomized study to assess postoperative morbidity and pancreatic function after pancreaticoduodenectomy with pancreaticojejunostomy and duct occlusion without pancreaticojejunostomy.
- Meta-analysis of pancreaticojejunostomy versus pancreaticogastrostomy reconstruction after pancreaticoduodenectomyA McKay
Department of Surgery, University of Calgary, Calgary, Canada
Br J Surg 93:929-36. 2006b>Pancreaticoduodenectomy is the primary treatment for periampullary cancer. Associated morbidity is high and often related to pancreatic anastomotic failure...
- Duodenum-preserving pancreatic head resection versus pancreatoduodenectomy for surgical treatment of chronic pancreatitis: a systematic review and meta-analysisMarkus K Diener
Department of General, Visceral and Trauma Surgery, University of Heidelberg, Heidelberg, Germany
Ann Surg 247:950-61. 2008....
- Treatment guidelines for branch duct type intraductal papillary mucinous neoplasms of the pancreas: when can we operate or observe?Jin Young Jang
Department of Surgery, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul, South Korea
Ann Surg Oncol 15:199-205. 2008..However, no definite treatment guideline (with respect to surgery or observation) has been issued on the management of branch duct type IPMN...
- Validation of potential early diagnostic and prognostic markers for pancreatic caPaul Chiao; Fiscal Year: 2007..survival of patients with pancreatic cancer can be improved by using therapeutic approaches such as pancreaticoduodenectomy plus chemoradiation. The most promising approach for the early diagnosis of cancer utilizes tumor markers...
- CORRELATES AND TREATMENT OF PANCREATIC CARCINOMACharles Yeo; Fiscal Year: 1993..of patients present with incurable disease, and of those that are candidates for surgical resection by pancreaticoduodenectomy, few survive five-years...
- ALLOGENIC PANCREATIC TUMOR VACCINE CELL LINEElizabeth Jaffee; Fiscal Year: 2003..radiation and chemotherapy are only palliative with small effects on disease- free survival following pancreaticoduodenectomy. Moreover, no methods are available for primary prevention or early screening...
- Biomarkers of COX-2 inhibitors in intraductal papillary mucinous neoplasm (IPMN)Christian Schmidt; Fiscal Year: 2007..unreadable] [unreadable] [unreadable]..
- Influence of Tumor Immunogenicity to ImmunotherapyJeffrey Norton; Fiscal Year: 2006..unreadable] [unreadable]..
- INJURY TO LIVER SINUSOIDAL ENDOTHELIAL CELLSSteven Strasberg; Fiscal Year: 2003..A potentially beneficial improvements in preservation solutions are identified they will be tested in whole isolated livers and by transplantation in the rat. ..
- Hepatic Arterial Flouridine and IV Bevacizumab for Primary Hepatic MalignancyWilliam Jarnagin; Fiscal Year: 2008..Furthermore, several important clinical issues are addressed by the proposed correlative studies, the results of which would be of broad general interest in clinical oncology. [unreadable] [unreadable] [unreadable]..
- Role of Somatostatin Receptors in Pancreatic CancerWilliam Fisher; Fiscal Year: 2003..Since somatostatin expression has been demonstrated in other tumor types, the findings may also be relevant to other cancers. ..
- Increasing Functional Liver Mass in Health and DiseaseLeonidas Koniaris; Fiscal Year: 2005..2) Determine the extent to which and mechanisms by which co-administrating HCF and Follistatin along with IL-6 facilitates the liver growth response and reduces IL-6 associated toxicity. ..
- The Role of GDF-15 in Organ InjuryLeonidas Koniaris; Fiscal Year: 2005..The completion of this mentored research training will further the candidate?s goal of applying bench-derived scientific discovery to the treatment of surgical disease as an independent investigator. ..
- MMP-9 mediates cerebral edema in fulminant liver failureJustin Nguyen; Fiscal Year: 2004..2. To determine whether cerebral edema is attenuated in MMP-9 knockout mice following experimentally induced FHF. ..
- Tracked Laparoscopic Ultrasound for Use in Liver SurgeryPhilip Bao; Fiscal Year: 2004..Ultimately, the success of this project may improve care for and expand the population who will benefit from surgical therapy of liver cancer. ..
- MMP-9 in Blood-Brain Barrier Failure in Fulminant Hepatic FailureJustin Nguyen; Fiscal Year: 2009..Specific Aim 2: To determine if inhibition of MMP-9 results in an increase in survival in experimentally induced FHF. ..