pancreaticoduodenectomy

Summary

Summary: The excision of the head of the pancreas and the encircling loop of the duodenum to which it is connected.

Top Publications

  1. ncbi Preoperative biliary drainage for cancer of the head of the pancreas
    Niels A van der Gaag
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    N Engl J Med 362:129-37. 2010
  2. ncbi Pancreatogastrostomy with gastric partition after pylorus-preserving pancreatoduodenectomy versus conventional pancreatojejunostomy: a prospective randomized study
    Laureano Fernandez-Cruz
    ICMDM Department of Surgery, Hospital Clinic de Barcelona, Barcelona, Spain
    Ann Surg 248:930-8. 2008
  3. pmc One thousand consecutive pancreaticoduodenectomies
    John L Cameron
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Ann Surg 244:10-5. 2006
  4. pmc Reconstruction by pancreaticojejunostomy versus pancreaticogastrostomy following pancreatectomy: results of a comparative study
    Claudio Bassi
    Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, Hospital G B Rossi, University of Verona, 37134 Verona, Italy
    Ann Surg 242:767-71, discussion 771-3. 2005
  5. pmc Conventional versus binding pancreaticojejunostomy after pancreaticoduodenectomy: a prospective randomized trial
    Shu You Peng
    General Surgery Department, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jie Fang Road, Hangzhou 310009, China
    Ann Surg 245:692-8. 2007
  6. ncbi Most pancreatic cancer resections are R1 resections
    Irene Esposito
    Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 220, 69120 Heidelberg, Germany
    Ann Surg Oncol 15:1651-60. 2008
  7. ncbi Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trial
    Claudio Bassi
    Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, Hospital G B Rossi University of Verona, Piazzale L A Scuro, 37134 Verona, Italy
    Surgery 134:766-71. 2003
  8. ncbi Pancreaticoduodenectomy with vascular resection for local advanced pancreatic head cancer: a single center retrospective study
    Chunyou Wang
    Pancreatic Center, Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Ave 1277, Wuhan City, Hubei Province, 430022, China
    J Gastrointest Surg 12:2183-90. 2008
  9. ncbi Binding pancreaticojejunostomy is a new technique to minimize leakage
    Shuyou Peng
    Department of Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Province, People s Republic of, 310009, Hangzhou, China
    Am J Surg 183:283-5. 2002
  10. ncbi Pylorus ring resection reduces delayed gastric emptying in patients undergoing pancreatoduodenectomy: a prospective, randomized, controlled trial of pylorus-resecting versus pylorus-preserving pancreatoduodenectomy
    Manabu Kawai
    Second Department of Surgery, Wakayama Medical University School of Medicine, Wakayama, Japan
    Ann Surg 253:495-501. 2011

Detail Information

Publications323 found, 100 shown here

  1. ncbi Preoperative biliary drainage for cancer of the head of the pancreas
    Niels A van der Gaag
    Department of Surgery, Academic Medical Center, Amsterdam, The Netherlands
    N Engl J Med 362:129-37. 2010
    ..The benefits of preoperative biliary drainage, which was introduced to improve the postoperative outcome in patients with obstructive jaundice caused by a tumor of the pancreatic head, are unclear...
  2. ncbi Pancreatogastrostomy with gastric partition after pylorus-preserving pancreatoduodenectomy versus conventional pancreatojejunostomy: a prospective randomized study
    Laureano Fernandez-Cruz
    ICMDM Department of Surgery, Hospital Clinic de Barcelona, Barcelona, Spain
    Ann Surg 248:930-8. 2008
    ..the results of postoperative morbidity rate of a new pancreatogastrostomy technique, pylorus-preserving pancreaticoduodenectomy (PPPD) with gastric partition (PPPD-GP) with the conventional technique of pancreaticojejunostomy (PJ).
  3. pmc One thousand consecutive pancreaticoduodenectomies
    John L Cameron
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Ann Surg 244:10-5. 2006
    To trace the evolution of pancreaticoduodenectomy from the decade of the 1960s through the first decade of the new Millenium, through the experience of one surgeon doing 1000 consecutive operations.
  4. pmc Reconstruction by pancreaticojejunostomy versus pancreaticogastrostomy following pancreatectomy: results of a comparative study
    Claudio Bassi
    Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, Hospital G B Rossi, University of Verona, 37134 Verona, Italy
    Ann Surg 242:767-71, discussion 771-3. 2005
    To compare the results of pancreaticogastrostomy versus pancreaticojejunostomy following pancreaticoduodenectomy in a prospective and randomized setting.
  5. pmc Conventional versus binding pancreaticojejunostomy after pancreaticoduodenectomy: a prospective randomized trial
    Shu You Peng
    General Surgery Department, Second Affiliated Hospital, School of Medicine, Zhejiang University, 88 Jie Fang Road, Hangzhou 310009, China
    Ann Surg 245:692-8. 2007
    This study compared the postoperative pancreatic anastomosis leakage rate of a new binding technique with the conventional technique of pancreaticojejunostomy after pancreaticoduodenectomy.
  6. ncbi Most pancreatic cancer resections are R1 resections
    Irene Esposito
    Institute of Pathology, University of Heidelberg, Im Neuenheimer Feld 220, 69120 Heidelberg, Germany
    Ann Surg Oncol 15:1651-60. 2008
    ..Although general guidelines for the processing of pancreatic specimens have been established, there is currently no widely accepted standardized protocol for pathological examination, especially with respect to resection margins...
  7. ncbi Duct-to-mucosa versus end-to-side pancreaticojejunostomy reconstruction after pancreaticoduodenectomy: results of a prospective randomized trial
    Claudio Bassi
    Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, Hospital G B Rossi University of Verona, Piazzale L A Scuro, 37134 Verona, Italy
    Surgery 134:766-71. 2003
    Anastomotic failure is still a significant problem that affects the outcome of pancreaticoduodenectomy. There have been many techniques proposed for the reconstruction of pancreatic digestive continuity, but there have been few ..
  8. ncbi Pancreaticoduodenectomy with vascular resection for local advanced pancreatic head cancer: a single center retrospective study
    Chunyou Wang
    Pancreatic Center, Department of General Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Jiefang Ave 1277, Wuhan City, Hubei Province, 430022, China
    J Gastrointest Surg 12:2183-90. 2008
    b>Pancreaticoduodenectomy with vascular resection remains a controversial approach for patients with local advanced pancreatic head cancer for the lack of evidences of survival and quality of life benefits...
  9. ncbi Binding pancreaticojejunostomy is a new technique to minimize leakage
    Shuyou Peng
    Department of Surgery, Second Affiliated Hospital, School of Medicine, Zhejiang University, Zhejiang Province, People s Republic of, 310009, Hangzhou, China
    Am J Surg 183:283-5. 2002
    b>Pancreaticoduodenectomy (Whipple procedure) has been the standard treatment for periampullary and pancreatic carcinoma...
  10. ncbi Pylorus ring resection reduces delayed gastric emptying in patients undergoing pancreatoduodenectomy: a prospective, randomized, controlled trial of pylorus-resecting versus pylorus-preserving pancreatoduodenectomy
    Manabu Kawai
    Second Department of Surgery, Wakayama Medical University School of Medicine, Wakayama, Japan
    Ann Surg 253:495-501. 2011
    ....
  11. pmc Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma, part 2: randomized controlled trial evaluating survival, morbidity, and mortality
    Charles J Yeo
    Department of Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland 21287, USA
    Ann Surg 236:355-66; discussion 366-8. 2002
    To evaluate, in a prospective, randomized single-institution trial, the end points of operative morbidity, operative mortality, and survival in patients undergoing standard versus radical (extended) pancreaticoduodenectomy.
  12. ncbi Laparoscopic pancreaticoduodenectomy: technique and outcomes
    Chinnasamy Palanivelu
    Department of Gastrointestinal and Minimally Invasive Surgery, GEM Hospital, Coimbatore, India
    J Am Coll Surg 205:222-30. 2007
    We describe our experience with laparoscopic pancreaticoduodenectomy, including 5-year actuarial survival rates.
  13. ncbi Pancreaticoduodenectomy with vascular resection: margin status and survival duration
    Jennifer F Tseng
    Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    J Gastrointest Surg 8:935-49; discussion 949-50. 2004
    Major vascular resection performed at the time of pancreaticoduodenectomy (PD) for adenocarcinoma remains controversial...
  14. ncbi Laparoscopic pancreaticoduodenectomy for benign and malignant diseases
    J L Dulucq
    Department of Abdominal Surgery, ILS, Maison de Santé Protestante, Bagatelle, MSPB, Route de Toulouse 203, 33401, Talence Bordeaux, France
    Surg Endosc 20:1045-50. 2006
    ..To the best of the authors' knowledge, their series of laparoscopic pancreatoduodenectomies is the largest reported to date...
  15. ncbi Defining morbidity after pancreaticoduodenectomy: use of a prospective complication grading system
    Stephen R Grobmyer
    Gastric and Mixed Tumor Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA
    J Am Coll Surg 204:356-64. 2007
    ..Improving surgical quality of care requires accurate reporting of postoperative complications...
  16. ncbi Complications after pancreatoduodenectomy: imaging and imaging-guided interventional procedures
    D A Gervais
    Department of Radiology, Division of Abdominal Imaging and Intervention, Massachusetts General Hospital, 55 Fruit St, Boston, MA 02114, USA
    Radiographics 21:673-90. 2001
    ....
  17. ncbi Laparoscopic pancreatoduodenectomy: a review of 285 published cases
    Andrew A Gumbs
    Department of Surgical Oncology, Fox Chase Cancer Center, Philadelphia, PA, USA
    Ann Surg Oncol 18:1335-41. 2011
    ..As the technique becomes more diffuse, issues regarding the adequacy of oncologic margins and lymph node retrieval need to be addressed...
  18. pmc Serum CA 19-9 as a marker of resectability and survival in patients with potentially resectable pancreatic cancer treated with neoadjuvant chemoradiation
    Matthew H G Katz
    Department of Surgery, The University of California, Orange, CA, USA
    Ann Surg Oncol 17:1794-801. 2010
    ..We evaluated CA 19-9 as a marker of therapeutic response, completion of therapy, and survival in patients enrolled on two recently reported clinical trials...
  19. ncbi A surgical and pathological based classification of resective treatment of pancreatic cancer. Summary of an international workshop on surgical procedures in pancreatic cancer
    S Pedrazzoli
    Dipartimento di Scienze Mediche e Chirurgiche, Semeiotica Chirurgica, University of Padova, Italy
    Dig Surg 16:337-45. 1999
    ..The extent of pancreatic resection and lymphadenectomy, both for Kausch-Whipple pancreatoduodenectomy and for left pancreatectomy, is variable between surgeons, according to their training...
  20. ncbi Can laparoscopic pancreaticoduodenectomy be safely implemented?
    Amer H Zureikat
    Department of Surgery, Division of Surgical Oncology, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    J Gastrointest Surg 15:1151-7. 2011
    The implementation of laparoscopic pancreaticoduodenectomy (LPD) has been appropriately met with apprehension, and concerns exist regarding outcomes early in a program's experience. We reviewed our early experience and outcomes of LPD.
  21. ncbi External pancreatic duct stent decreases pancreatic fistula rate after pancreaticoduodenectomy: prospective multicenter randomized trial
    Patrick Pessaux
    Pôle des Pathologies Digestives, Hépatiques et de la Transplantation, Hopital de Hautepierre, Universite de Strasbourg, France
    Ann Surg 253:879-85. 2011
    Pancreatic fistula (PF) is a leading cause of morbidity and mortality after pancreaticoduodenectomy (PD)...
  22. ncbi Fatty pancreas and increased body mass index are risk factors of pancreatic fistula after pancreaticoduodenectomy
    Sebastien Gaujoux
    Department of Hepato pancreato biliary Surgery, Pôle des Maladies de l Appareil Digestif PMAD, Paris, France
    Surgery 148:15-23. 2010
    ..Pancreatic fistula (PF) after pancreatoduodenectomy (PD) remains a challenging problem. The only commonly accepted risk factor is the soft consistency of the pancreatic remnant...
  23. ncbi Pancreaticogastrostomy decreased relaparotomy caused by pancreatic fistula after pancreaticoduodenectomy compared with pancreaticojejunostomy
    Elie Oussoultzoglou
    Centre de Chirurgie Viscerale et de Transplantation, Hôpital Universitaire de Hautepierre, Strasbourg, Strasbourg Cedex, France
    Arch Surg 139:327-35. 2004
    Pancreaticogastrostomy (PG) is associated with a lower relaparotomy rate following pancreaticoduodenectomy (PD) than pancreaticojejunostomy (PJ).
  24. ncbi Does pancreatic duct stenting decrease the rate of pancreatic fistula following pancreaticoduodenectomy? Results of a prospective randomized trial
    Jordan M Winter
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Gastrointest Surg 10:1280-90; discussion 1290. 2006
    ..duct stenting remains an attractive strategy to reduce the incidence of pancreatic fistulas following pancreaticoduodenectomy (PD) with encouraging results in both retrospective and prospective studies...
  25. ncbi Risk of malignancy in resected cystic tumors of the pancreas < or =3 cm in size: is it safe to observe asymptomatic patients? A multi-institutional report
    C J Lee
    University of Michigan Medical Center, Ann Arbor, MI 48109, USA
    J Gastrointest Surg 12:234-42. 2008
    ..3%. This study suggests that a group of patients with small cystic pancreatic neoplasms who have low risk of malignancy can be identified, and selective resection of these lesions may be appropriate...
  26. ncbi Pancreatic anastomoses after pancreaticoduodenectomy: do we need further studies?
    Shailesh V Shrikhande
    Department of Gastrointestinal Surgical Oncology, Tata Memorial Hospital, Dr Ernest Borges Marg, Parel, Mumbai, 400 012, India
    World J Surg 29:1642-9. 2005
    ..the single most important factor responsible for the considerable morbidity and mortality associated with pancreaticoduodenectomy. Management of the pancreatic remnant is controversially discussed, reflecting the complexity of ..
  27. pmc Assessment of complications after pancreatic surgery: A novel grading system applied to 633 patients undergoing pancreaticoduodenectomy
    Michelle L DeOliveira
    Swiss HPB Hepato Pancreato Biliary Center, Department of Visceral and Transplantation Surgery, Zurich University Hospital, Zurich, Switzerland
    Ann Surg 244:931-7; discussion 937-9. 2006
    To define a simple and reproducible classification of complications following pancreaticoduodenectomy (PD) based on a therapy-oriented severity grading system.
  28. pmc External drainage of pancreatic duct with a stent to reduce leakage rate of pancreaticojejunostomy after pancreaticoduodenectomy: a prospective randomized trial
    Ronnie T P Poon
    Department of Surgery, Queen Mary Hospital, The University of Hong Kong, Hong Kong, China
    Ann Surg 246:425-33; discussion 433-5. 2007
    Pancreatic fistula is a leading cause of morbidity and mortality after pancreaticoduodenectomy. External drainage of pancreatic duct with a stent has been shown to reduce pancreatic fistula rate of pancreaticojejunostomy in a few ..
  29. ncbi Risk factors of pancreatic leakage after pancreaticoduodenectomy
    Yin Mo Yang
    Department of Surgery, The First Teaching Hospital, Health Science Center, Beijing University, Beijing 100034, China
    World J Gastroenterol 11:2456-61. 2005
    To analyze the risk factors for pancreatic leakage after pancreaticoduodenectomy (PD) and to evaluate whether duct-to-mucosa pancreaticojejunostomy could reduce the risk of pancreatic leakage.
  30. pmc Pylorus preserving pancreaticoduodenectomy versus standard Whipple procedure: a prospective, randomized, multicenter analysis of 170 patients with pancreatic and periampullary tumors
    Khe T C Tran
    Department of General Surgery, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
    Ann Surg 240:738-45. 2004
    ..randomized multicenter study was performed to assess whether the results of pylorus-preserving pancreaticoduodenectomy (PPPD) equal those of the standard Whipple (SW) operation, especially with respect to duration of surgery,..
  31. ncbi Total laparoscopic pancreaticoduodenectomy: feasibility and outcome in an early experience
    Michael L Kendrick
    Department of Surgery, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
    Arch Surg 145:19-23. 2010
    Total laparoscopic pancreaticoduodenectomy is a safe and effective therapeutic approach.
  32. ncbi Preoperative CA19-9 levels and lymph node ratio are independent predictors of survival in patients with resected pancreatic ductal adenocarcinoma
    R A Smith
    Division of Surgery and Oncology, School of Cancer Studies, University of Liverpool, Liverpool, UK
    Dig Surg 25:226-32. 2008
    ....
  33. ncbi Pylorus-preserving pancreaticoduodenectomy versus conventional pancreaticoduodenectomy for pancreatic adenocarcinoma
    Masaji Tani
    Second Department of Surgery, Wakayama Medical University, School of Medicine, 811 1 Kimiidera, Wakayama, 641 8510, Japan
    Surg Today 39:219-24. 2009
    A few randomized controlled trials have questioned the justification of pylorus-preserving pancreaticoduodenectomy (PpPD) for pancreatic cancer and periampullary cancer...
  34. ncbi Laparoscopic robotic-assisted pancreaticoduodenectomy: a case-matched comparison with open resection
    S Chalikonda
    Department of General Surgery, Cleveland Clinic Foundation, A100, 9500 Euclid Avenue A100, Cleveland, OH 44195, USA
    Surg Endosc 26:2397-402. 2012
    Minimally invasive procedures have expanded recently to include pancreaticoduodenectomy (PD), but the efficacy of a laparoscopic robotic-assisted approach has not been demonstrated...
  35. ncbi Effect of neoadjuvant chemoradiation on operative mortality and morbidity for pancreaticoduodenectomy
    Tsung Yen Cheng
    Department of Surgery, Duke University Medical Center, Box 3118, Durham, North Carolina 27710, USA
    Ann Surg Oncol 13:66-74. 2006
    Neoadjuvant chemoradiotherapy (neo-CRT) is being used with increasing frequency for periampullary tumors, but how it alters the complication rate of pancreaticoduodenectomy (PD) is unclear.
  36. ncbi Early versus late drain removal after standard pancreatic resections: results of a prospective randomized trial
    Claudio Bassi
    Department of Surgery, G B Rossi Hospital, University of Verona, Verona, Italy
    Ann Surg 252:207-14. 2010
    ..The role of surgically placed intra-abdominal drainages after pancreatic resections has not been clearly established. In particular, their effect on morbidity rates and the optimal timing for their removal remains controversial...
  37. ncbi Subtotal stomach-preserving pancreaticoduodenectomy (SSPPD) prevents postoperative delayed gastric emptying
    Hiroshi Kurahara
    Department of Surgical Oncology and Digestive Surgery, Graduate School of Medical Sciences, Kagoshima University, Japan
    J Surg Oncol 102:615-9. 2010
    Delayed gastric emptying (DGE) is one of main complications after pylorus-preserving pancreaticoduodenectomy (PPPD) with regional lymph node dissection (RLND)...
  38. ncbi Randomized clinical trial to assess the efficacy of ulinastatin for postoperative pancreatitis following pancreaticoduodenectomy
    Kenichiro Uemura
    Department of Surgery, Graduate School of Biochemical Sciences, Hiroshima University, Hiroshima, Japan
    J Surg Oncol 98:309-13. 2008
    ..The aim of this study was to assess the efficacy of ulinastatin for postoperative pancreatitis following pancreaticoduodenectomy in a randomized clinical trial.
  39. ncbi Prognostic relevance of lymph node ratio following pancreaticoduodenectomy for pancreatic cancer
    Timothy M Pawlik
    Department of Surgery, The Sol Goldman Pancreatic Cancer Research Center, The Johns Hopkins University School of Medicine, Baltimore, MD 22187 6681, USA
    Surgery 141:610-8. 2007
    ..investigated the ratio of the number of lymph nodes harboring metastatic cancer to the total number of lymph nodes examined (lymph node ratio [LNR]) with regard to outcome after pancreaticoduodenectomy for ductal cancer of the pancreas.
  40. ncbi Pancreaticoduodenectomy for pancreatic head cancer: PPPD versus Whipple procedure
    Pin Wen Lin
    Department of Surgery, Institute of Clinical Medicine, School of Medicine National Cheng Kung University, Tainan, Taiwan
    Hepatogastroenterology 52:1601-4. 2005
    Resectable carcinoma of the head of the pancreas can be treated with either standard (the Whipple) or pylorus-preserving pancreaticoduodenectomy (PPPD). Only a few reports compared the differences between these two procedures.
  41. ncbi Survival after pancreaticoduodenectomy is not improved by extending resections to achieve negative margins
    Jonathan Hernandez
    Center for Digestive Disorders, Department of Surgery, University of South Florida, Tampa General Hospital, Tampa, Florida 33601, USA
    Ann Surg 250:76-80. 2009
    ..This study was undertaken to determine the survival benefit of extending resections to obtain microscopically negative margins after positive intraoperative frozen sections...
  42. ncbi Current status of robot-assisted laparoscopic pancreaticoduodenectomy and distal pancreatectomy: a comprehensive review
    Eric C H Lai
    Department of Surgery, Pamela Youde Nethersole Eastern Hospital, Hong Kong SAR, China
    Asian J Endosc Surg 6:158-64. 2013
    This article reviews the current status of robot-assisted laparoscopic pancreaticoduodenectomy and distal pancreatectomy.
  43. ncbi Chronic pancreatitis: early results of pancreatoduodenectomy and analysis of risk factors
    Felix Ruckert
    Department of General, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany
    Pancreas 40:925-30. 2011
    ....
  44. ncbi Robot-assisted laparoscopic pancreaticoduodenectomy versus open pancreaticoduodenectomy--a comparative study
    Eric C H Lai
    Department of Surgery, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong SAR, China
    Int J Surg 10:475-9. 2012
    ..The recently developed robotic technology allows surgeons to perform pancreaticoduodenectomy. A comparative study was undertaken to study outcomes between robotic approach and open approach.
  45. ncbi Clinical significance of pathologic subtype in curatively resected ampulla of vater cancer
    Woo Seok Kim
    Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea
    J Surg Oncol 105:266-72. 2012
    ..The aims of this study were to identify those factors that affect recurrence after curative resection and to investigate differences between the clinicopathologic features of these two pathologic subtypes...
  46. ncbi Preoperative serum C-reactive protein levels and post-operative lymph node ratio are important predictors of survival after pancreaticoduodenectomy for pancreatic ductal adenocarcinoma
    Pandanaboyana Sanjay
    Ninewells Hospital and Medical School, University of Dundee, Dundee, United Kingdom
    JOP 13:199-204. 2012
    ..There is paucity of data on the prognostic value of pre-operative inflammatory response and post-operative lymph node ratio on patient survival after pancreatic-head resection for pancreatic ductal adenocarcinoma...
  47. ncbi Quality of life in patients after pancreaticoduodenectomy for chronic pancreatitis
    Felix Ruckert
    Department of General, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Technische Universitat Dresden, Fetscherstrasse 74, 01307 Dresden, Germany
    J Gastrointest Surg 15:1143-50. 2011
    b>Pancreaticoduodenectomy (PD) is the most frequently performed resectional procedure in chronic pancreatitis. Only a few studies have evaluated quality of life (QOL) after PD for chronic pancreatitis...
  48. pmc Perineural and intraneural invasion in posttherapy pancreaticoduodenectomy specimens predicts poor prognosis in patients with pancreatic ductal adenocarcinoma
    Deyali Chatterjee
    Departments of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Am J Surg Pathol 36:409-17. 2012
    ..However, the prognostic significance of PNI in patients with PDAC who received neoadjuvant therapy and pancreaticoduodenectomy is not clear...
  49. ncbi Laparoscopic vs open pancreaticoduodenectomy: overall outcomes and severity of complications using the Accordion Severity Grading System
    Horacio J Asbun
    Department of General Surgery, Mayo Clinic, 4500 San Pablo Rd, Jacksonville, FL 32224, USA
    J Am Coll Surg 215:810-9. 2012
    Minimal access surgery techniques have evolved to include complex surgical procedures. Laparoscopic pancreaticoduodenectomy (LPD) is a complex operation that pancreas surgeons have been slow to adopt...
  50. pmc Evolution of the Whipple procedure at the Massachusetts General Hospital
    Carlos Fernandez-del Castillo
    Department of Surgery, Massachusetts General Hospital, Boston, MA 02114, USA
    Surgery 152:S56-63. 2012
    ..The goal of this study was to investigate the evolution of pancreatoduodenectomy at the Massachusetts General Hospital (MGH)...
  51. ncbi Robotic versus open pancreaticoduodenectomy: a comparative study at a single institution
    Nicolas Christian Buchs
    Division of General, Minimally Invasive and Robotic Surgery, Department of Surgery, University of Illinois at Chicago, 840 S Wood Street, Suite 435 E, Chicago, IL 60612, USA
    World J Surg 35:2739-46. 2011
    Minimally invasive pancreaticoduodenectomy (PD) remains one of the most challenging abdominal procedures, and its application is poorly reported in the literature so far...
  52. ncbi A prospective randomized trial comparing standard pancreatoduodenectomy with pancreatoduodenectomy with extended lymphadenectomy in resectable pancreatic head adenocarcinoma
    Michael B Farnell
    Mayo Clinic, Rochester, Minnesota 55905, USA
    Surgery 138:618-28; discussion 628-30. 2005
    ..To compare operative morbidity, mortality, quality of life, and survival after pancreatoduodenectomy (PD) versus pancreatoduodenectomy with extended lymphadenectomy (PD/ELND) in patients with resectable pancreatic cancer...
  53. pmc A systematic review and meta-analysis of pylorus-preserving versus classical pancreaticoduodenectomy for surgical treatment of periampullary and pancreatic carcinoma
    Markus K Diener
    University of Heidelberg, Department of General, Visceral and Trauma Surgery, Heidelberg, Germany
    Ann Surg 245:187-200. 2007
    Comparison of effectiveness between the pylorus-preserving pancreaticoduodenectomy ("pylorus-preserving Whipple" [PPW]) and the classic Whipple (CW) procedure.
  54. ncbi Laparoscopic pancreaticoduodenectomy: a retrospective review of 19 cases
    Raffaele Pugliese
    Department of Surgery, Niguarda Hospital, Milan, Italy
    Surg Laparosc Endosc Percutan Tech 18:13-8. 2008
    ..This study was designed to assess the feasibility and results of laparoscopic pancreaticoduodenectomy for neoplasms of the pancreatic head, analyzing steps of learning curve, conversion rate, and short-term ..
  55. pmc Low-dose erythromycin reduces delayed gastric emptying and improves gastric motility after Billroth I pylorus-preserving pancreaticoduodenectomy
    S Ohwada
    Second Department of Surgery, Gunma University Faculty of Medicine, Maebashi, Japan
    Ann Surg 234:668-74. 2001
    ..that early and low doses of erythromycin reduce the incidence of early delayed gastric emptying (DGE) and induce phase 3 of the migratory motor complex in the stomach after Billroth I pylorus-preserving pancreaticoduodenectomy (PPPD).
  56. pmc Clinical and economic validation of the International Study Group of Pancreatic Fistula (ISGPF) classification scheme
    Wande B Pratt
    Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA
    Ann Surg 245:443-51. 2007
    The authors sought to validate the ISGPF classification scheme in a large cohort of patients following pancreaticoduodenectomy (PD) in a pancreaticobiliary surgical specialty unit.
  57. ncbi Prevention and management of pancreatic fistula
    Mark P Callery
    Department of Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, 330 Brookline Avenue, ST 9, Boston, MA 02215, USA
    J Gastrointest Surg 13:163-73. 2009
    ..Key citations from the past seventeen years have been scrutinized, and together with personal experience, provide the basis for this review...
  58. ncbi Risk factors of pancreatic fistula and delayed gastric emptying after pancreaticoduodenectomy with pancreaticogastrostomy
    Emilie Lermite
    Department of Digestive Surgery, University Hospital, Angers, France
    J Am Coll Surg 204:588-96. 2007
    ..gastric emptying (DGE) are, respectively, the most frightening and most frequent complications after pancreaticoduodenectomy (PD)...
  59. ncbi Development of nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis (NASH) after pancreaticoduodenectomy: proposal of a postoperative NAFLD scoring system
    Hiroyuki Kato
    Department of Hepatobiliary Pancreatic and Transplant Surgery, Mie University Graduate School of Medicine, Tsu, Mie, 514 8507, Japan
    J Hepatobiliary Pancreat Sci 17:296-304. 2010
    The main etiology of NAFLD and NASH after pancreatic resection is still unclear, and the therapeutic strategy has yet to be established. The focus of this review is how predict and prevent NAFLD/NASH after pancreaticoduodenectomy.
  60. ncbi Survival analysis after pancreatic resection for ampullary and pancreatic head carcinoma: an analysis of clinicopathological factors
    C A M Sommerville
    Division of Surgery and Cancer, HPB Unit, Hammersmith Hospital, Imperial College, London, England
    J Surg Oncol 100:651-6. 2009
    Surgery remains the only curative option for the treatment of pancreatic and ampullary carcinomas. To examine the survival differences between ampullary and pancreatic head carcinomas after pancreaticoduodenectomy.
  61. ncbi Diagnostic ascertainment of suspicious pancreatic mass: a threshold analysis
    Amnon Sonnenberg
    Portland VA Medical Center, Portland, Oregon 97239, USA
    Clin Gastroenterol Hepatol 6:1162-6. 2008
    ..It is frequently difficult to differentiate between a benign and malignant pancreatic mass. The aim of this study was to assess the parameters that affect the decision to perform surgery on a suspicious pancreatic head lesion...
  62. ncbi Very high serum CA 19-9 levels: a contraindication to pancreaticoduodenectomy?
    O Turrini
    Department of Surgery, Indiana University School of Medicine, Indianapolis, IN, USA
    J Gastrointest Surg 13:1791-7. 2009
    ..To assess the outcome of patients with resectable pancreatic adenocarcinoma (PA) associated with high serum CA 19-9 levels...
  63. ncbi Conservative management of pancreatic fistula after pancreaticoduodenectomy with pancreaticogastrostomy
    Nicolas Munoz-Bongrand
    Department of Digestive Surgery, Hopital Beaujon, AP HP, University Paris VII, Clichy, France
    J Am Coll Surg 199:198-203. 2004
    Pancreatic fistula (PF), which is a major complication of pancreaticoduodenectomy (PD), can be treated conservatively or by reoperation...
  64. pmc A simple scoring system based on clinical factors related to pancreatic texture predicts postoperative pancreatic fistula preoperatively
    Ulrich Friedrich Wellner
    Department of General and Visceral Surgery Institute of Pathology, University Hospital Freiburg, Freiburg, Germany
    HPB (Oxford) 12:696-702. 2010
    ..Postoperative pancreatic fistula (POPF) is regarded as the most serious complication of pancreatic surgery. The preoperative risk stratification of patients by simple means is of interest in perioperative clinical management...
  65. ncbi Decreasing the pancreatic leak rate after pancreaticoduodenectomy
    Ronnie T P Poon
    Department of Surgery, The University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Road, Hong Kong, China
    Adv Surg 42:33-48. 2008
    Although pancreaticoduodenectomy has become a safe and effective procedure for benign and malignant pancreatic diseases in recent years, leakage of pancreaticoenteric anastomosis still remains a major cause of morbidity and even ..
  66. ncbi Large-cell neuroendocrine carcinoma of the ampulla of Vater
    Z Stojsic
    Institute of Pathology, School of Medicine, University of Belgrade, Dr Subotica 1 II, 11000, Belgrade, Serbia
    Med Oncol 27:1144-8. 2010
    ..3 and 61%, respectively. Two months after surgery, liver metastases occurred, confirming highly aggressive behavior of large-cell neuroendocrine carcinoma...
  67. ncbi Endovascular management of hepatic artery pseudoaneurysm hemorrhage complicating pancreaticoduodenectomy
    John Harvey
    Vascular Surgery Service, Englewood Hospital and Medical Center, Englewood, NJ 07631, USA
    J Vasc Surg 43:613-7. 2006
    Gastrointestinal bleeding is a morbid complication of pancreaticoduodenectomy. Determining its etiology is often a daunting challenge in that both common and unusual mechanisms may be operative...
  68. pmc Delayed gastric emptying after pylorus-preserving pancreaticoduodenectomy: validation of International Study Group of Pancreatic Surgery classification and analysis of risk factors
    Giuseppe Malleo
    Department of Surgery, General Surgery B Unit, G B Rossi Hospital, University of Verona, Verona, Italy
    HPB (Oxford) 12:610-8. 2010
    ..study evaluates the incidence and clinical features and associated risk factors of delayed gastric emptying (DGE) after pancreaticoduodenectomy, employing the International Study Group of Pancreatic Surgery (ISGPS) consensus definition.
  69. ncbi Pancreaticoduodenectomy: role of interventional radiologists in managing patients and complications
    Taylor A Sohn
    Department of Surgery, The Johns Hopkins Medical Institutions, 600 North Wolfe Street, Blalock 606, Baltimore, MD 21287 4606, USA
    J Gastrointest Surg 7:209-19. 2003
    Although the mortality rate after pancreaticoduodenectomy has decreased, the morbidity rate remains high. Major morbidity is often managed with the aid of interventional radiologists...
  70. ncbi Evaluation of the International Study Group of Pancreatic Surgery definition of delayed gastric emptying after pancreatoduodenectomy in a high-volume centre
    T Welsch
    Department of General, Visceral and Transplantation Surgery, University Hospital Heidelberg, Heidelberg, Germany
    Br J Surg 97:1043-50. 2010
    ..Delayed gastric emptying (DGE) is a common complication after pancreatoduodenectomy. The International Study Group of Pancreatic Surgery (ISGPS) definition of DGE has not been evaluated and validated in a high-volume centre...
  71. ncbi A simple and safe anastomosis in pancreaticogastrostomy using mattress sutures
    Hiroaki Ohigashi
    Department of Surgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
    Am J Surg 196:130-4. 2008
    ..Postoperative amylase levels in the drainage fluid decreased significantly and none of the 17 patients developed pancreatic fistula formation. The technique is simple and shortens the time required for anastomosis...
  72. ncbi Does type of pancreaticojejunostomy after pancreaticoduodenectomy decrease rate of pancreatic fistula? A randomized, prospective, dual-institution trial
    Adam C Berger
    Department of Surgery, Thomas Jefferson University, Jefferson Pancreas, Biliary and Related Cancer Center, Philadelphia, PA 19107, USA
    J Am Coll Surg 208:738-47; discussion 747-9. 2009
    Pancreatic fistula (PF) is one of the most common complications after pancreaticoduodenectomy. There have been no large prospective randomized trials evaluating PF rates comparing invagination versus duct to mucosa pancreaticojejunostomy...
  73. ncbi Clinical characteristics of de novo nonalcoholic fatty liver disease following pancreaticoduodenectomy
    Naoki Tanaka
    Department of Metabolic Regulation, Institute on Aging and Adaptation, Shinshu University Graduate School of Medicine, Asahi 3 1 1, Matsumoto 390 8621, Japan
    J Gastroenterol 46:758-68. 2011
    ..We explored the clinical characteristics of newly appearing nonalcoholic fatty liver disease (NAFLD) after pancreaticoduodenectomy (PD), designated as de novo NAFLD after PD.
  74. ncbi Long-term pancreatic endocrine function following pancreatoduodenectomy with pancreaticogastrostomy
    Yoshiaki Murakami
    Department of Surgery, Division of Clinical Medical Science, Graduate School of Biomedical Sciences, Hiroshima University, Minami Ku, Hiroshima, Japan
    J Surg Oncol 97:519-22. 2008
    ..The aim of this study was to evaluate long-term pancreatic endocrine function following pancreatoduodenectomy with pancreaticogastrostomy...
  75. ncbi Omental flap in pancreaticoduodenectomy for protection of splanchnic vessels
    Atsuyuki Maeda
    Division of Hepato Biliary Pancreatic Surgery, Shizuoka Cancer Center Hospital, 1007 Shimo Nagakubo, 411 8777 Sunto Nagaizumi, Shizuoka, Japan
    World J Surg 29:1122-6. 2005
    Intraabdominal bleeding, the most life-threatening complication following pancreaticoduodenectomy (PD), most often is associated with failure of a pancreaticojejunostomy anastomosis or with intraabdominal infection...
  76. ncbi Incidence of pancreatic anastomotic failure and delayed gastric emptying after pancreatoduodenectomy in 507 consecutive patients: use of a web-based calculator to improve homogeneity of definition
    Yasushi Hashimoto
    Section of General, Vascular, and Thoracic Surgery, Virginia Mason Medical Center, Seattle, WA 98111, USA
    Surgery 147:503-15. 2010
    ..The solution might be to create a web-based calculator, test it for ambiguity and reliability with a large number of cases, and then make it available to the public...
  77. ncbi Early perioperative outcomes and pancreaticoduodenectomy in a general surgery residency training program
    Craig P Fischer
    Department of Surgery, The Methodist Hospital, Weill Medical College of Cornell University, Houston, TX 77030, USA
    J Gastrointest Surg 10:478-82. 2006
    ..b>Pancreaticoduodenectomy (PD) is a complex procedure performed infrequently by most surgical graduates...
  78. ncbi Effect of hospital volume on margin status after pancreaticoduodenectomy for cancer
    Karl Y Bilimoria
    Cancer Programs, American College of Surgeons, Chicago, IL 60611, USA
    J Am Coll Surg 207:510-9. 2008
    ..Our objective was to evaluate the effect of hospital pancreatectomy volume on margin status...
  79. ncbi A pancreaticoduodenectomy is acceptable for periampullary tumors in the elderly, even in patients over 80 years of age
    Masaji Tani
    Second Department of Surgery, Wakayama Medical University, School of Medicine, 811 1 Kimiidera, Wakayama, 641 8510, Japan
    J Hepatobiliary Pancreat Surg 16:675-80. 2009
    Although the mortality rates for pancreaticoduodenectomy have been reported to be low for periampullary tumors at high-volume centers, postoperative results still remain unclear for elderly patients over 80 years of age.
  80. ncbi 1423 pancreaticoduodenectomies for pancreatic cancer: A single-institution experience
    Jordan M Winter
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Gastrointest Surg 10:1199-210; discussion 1210-1. 2006
    b>Pancreaticoduodenectomy (PD) with the possible addition of neoadjuvant or adjuvant therapy is the standard of care in the United States for adenocarcinoma originating in the pancreatic head, neck, and uncinate process...
  81. ncbi Outcome of pancreaticoduodenectomy and impact of adjuvant therapy for ampullary carcinomas
    J H Lee
    Departments of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Int J Radiat Oncol Biol Phys 47:945-53. 2000
    ..To determine the clinical outcomes and potential impact of adjuvant chemoradiation in patients undergoing surgical resection of ampullary carcinoma...
  82. ncbi Long-term results of partial pancreaticoduodenectomy for ductal adenocarcinoma of the pancreatic head: 25-year experience
    Axel Richter
    Department of Surgery, University Hospital Mannheim, University of Heidelberg, Theodor Kutzer Ufer, 68167, Mannheim, Germany
    World J Surg 27:324-9. 2003
    ..We concluded that surgical treatment is "as good as it gets," as extended techniques have not proved to produce better results...
  83. ncbi Artificial nutrition after pancreaticoduodenectomy
    L Gianotti
    Department of Surgery, Scientific Institute San Raffaele Hospital, Milan, Italy
    Pancreas 21:344-51. 2000
    Patients undergoing pancreaticoduodenectomy (PD) often require postoperative artificial nutrition...
  84. ncbi An evidence-based approach to the surgical management of resectable pancreatic adenocarcinoma
    Alexander Stojadinovic
    Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY 10021, USA
    J Am Coll Surg 196:954-64. 2003
    ..We conducted a comprehensive review of prospective randomized clinical trials and summarized the contemporary treatment of resectable pancreatic carcinoma...
  85. ncbi A comparison of pancreaticogastrostomy and pancreaticojejunostomy following pancreaticoduodenectomy
    Gerard V Aranha
    Department of Surgery and Oncology Institute, Loyola University Stritch School of Medicine, Maywood, IL, USA
    J Gastrointest Surg 7:672-82. 2003
    ..Between the years of June 1995 and June 2001, 214 patients underwent pancreaticoduodenectomy (PD) at our institution. Of these 177 had PG and 97 had pancreatojejunostomy (PJ). There were 117 (54...
  86. ncbi Pancreaticoduodenectomy (Whipple resections) in patients without malignancy: are they all 'chronic pancreatitis'?
    Susan C Abraham
    Department of Pathology, Mayo Clinic, Rochester, Minnesota, 55905, USA
    Am J Surg Pathol 27:110-20. 2003
    b>Pancreaticoduodenectomy (Whipple resection) has evolved into a safe procedure in major high-volume medical centers for the treatment of pancreatic adenocarcinoma and refractory chronic pancreatitis...
  87. ncbi Pancreaticoduodenectomy with or without distal gastrectomy and extended retroperitoneal lymphadenectomy for periampullary adenocarcinoma--part 3: update on 5-year survival
    Taylor S Riall
    Departments of Surgery, The Sol Goldman Pancreas Cancer Research Center, Johns Hopkins Medical Institutions, Baltimore, Maryland, USA
    J Gastrointest Surg 9:1191-204; discussion 1204-6. 2005
    ..update the survival analysis at the 5-year mark of patients undergoing standard versus radical (extended) pancreaticoduodenectomy (PD) for periampullary adenocarcinoma (cancers of the pancreas, ampulla, common bile duct, and duodenum)...
  88. pmc Effect of preoperative biliary decompression on pancreaticoduodenectomy-associated morbidity in 300 consecutive patients
    P W Pisters
    Pancreatic Tumor Study Group, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030 4095, USA
    Ann Surg 234:47-55. 2001
    To examine the relationship between preoperative biliary drainage and the morbidity and mortality associated with pancreaticoduodenectomy.
  89. ncbi Management of complications after pancreaticoduodenectomy in a high volume centre: results on 150 consecutive patients
    C Bassi
    Surgical and Gastroenterological Department, Endocrine and Pancreatic Unit, University of Verona, Hospital G B Rossi, Verona, Italy
    Dig Surg 18:453-7; discussion 458. 2001
    b>Pancreaticoduodenectomy (PD) is still a difficult procedure with significant morbidity. We report 150 consecutive PDs performed during a 3-year period. All the cases have been prospectively evaluated with regard to the surgical outcome...
  90. ncbi Outcome after pancreaticoduodenectomy for cancer in elderly patients
    Radu Scurtu
    From the Centre de Chirurgie Viscérale et de Transplantation, Hopitaux Universitaires de Strasbourg, CHU Hautepierre, France
    J Gastrointest Surg 10:813-22. 2006
    During the last decade, the outcome after pancreaticoduodenectomy (PD) for cancer showed a continuous improvement. Therefore, an increasing number of patients, especially elderly patients, have been considered for this procedure...
  91. ncbi [A pancreas suture-less type II binding pancreaticogastrostomy]
    Shu You Peng
    Department of Surgery, the Sir Run Run Shaw Affiliated Hospital, Zhejiang University of Medicine, Hangzhou 310016, China
    Zhonghua Wai Ke Za Zhi 47:1764-6. 2009
    To explore the feasibility and safety of type II binding pancreaticogastrostomy (BPG) in pancreaticoduodenectomy and mid-segmentectomy of pancreas.
  92. ncbi Risk factors and outcomes in postpancreaticoduodenectomy pancreaticocutaneous fistula
    John W Lin
    Department of Surgery, Johns Hopkins Medical Institutions, Baltimore, MD 21287 4606, USA
    J Gastrointest Surg 8:951-9. 2004
    A significant fraction of patients undergoing pancreaticoduodenectomy develop a postoperative pancreaticocutaneous fistula...
  93. ncbi Delayed hemorrhage after pancreaticoduodenectomy
    Seong Ho Choi
    Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea South Korea
    J Am Coll Surg 199:186-91. 2004
    Postoperative hemorrhage, particularly delayed hemorrhage after pancreaticoduodenectomy, is a serious complication and one of the most common causes of mortality after pancreaticoduodenectomy.
  94. ncbi Determining pattern of recurrence following pancreaticoduodenectomy and adjuvant 5-flurouracil-based chemoradiation therapy: effect of number of metastatic lymph nodes and lymph node ratio
    Bolanle Asiyanbola
    Department of Surgery, Johns Hopkins Hospital, 600 North Wolfe Street, Halsted 614, Baltimore, MD 22187 6681, USA
    J Gastrointest Surg 13:752-9. 2009
    There are limited data on patterns of recurrence and factors associated with local recurrence following pancreaticoduodenectomy for pancreatic adenocarcinoma and adjuvant 5-flurouracil-based chemoradiation therapy.
  95. ncbi Systematic review of minimally invasive pancreatic resection
    Christopher D Briggs
    Cancer Biomarkers and Prevention Group, Department of Cancer Studies and Molecular Medicine, Bio centre, University of Leicester, University Road, Leicester LE1 7RH, UK
    J Gastrointest Surg 13:1129-37. 2009
    ..This article reviews the current published literature on the safety and efficacy of minimally invasive surgery of the pancreas...
  96. ncbi A new technique for pancreaticogastrostomy for the soft pancreas: the transfixing suture method
    Hiroyuki Shinchi
    Department of Surgical Oncology and Digestive Surgery, Kagoshima University Graduate School, 8 35 1 Sakuragaoka, Kagoshima, 890 8520, Japan
    J Hepatobiliary Pancreat Surg 13:212-7. 2006
    Pancreatic anastomotic leakage remains a persistent problem after pancreaticoduodenectomy (PD). The presence of soft, nonfibrotic pancreatic tissue is one of the most important risk factors for pancreatic leakage...
  97. ncbi Prevention of pancreatic anastomotic leakage after pancreaticoduodenectomy
    Ronnie Tung Ping Poon
    Department of Surgery, Centre for Study of Liver Disease, University of Hong Kong, Queen Mary Hospital, 102 Pokfulam Rd, Hong Kong, China
    Am J Surg 183:42-52. 2002
    Leakage at the pancreaticoenteric anastomosis remains a common and serious complication after pancreaticoduodenectomy. Over the past decade, various measures directed towards prevention of pancreatic leakage have been studied...
  98. pmc Occlusion of the pancreatic duct versus pancreaticojejunostomy: a prospective randomized trial
    Khe Tran
    Departments of General Surgery, Erasmus Medical Center Rotterdam, Rotterdam, The Netherlands
    Ann Surg 236:422-8; discussion 428. 2002
    Using a prospective randomized study to assess postoperative morbidity and pancreatic function after pancreaticoduodenectomy with pancreaticojejunostomy and duct occlusion without pancreaticojejunostomy.
  99. ncbi Meta-analysis of pancreaticojejunostomy versus pancreaticogastrostomy reconstruction after pancreaticoduodenectomy
    A McKay
    Department of Surgery, University of Calgary, Calgary, Canada
    Br J Surg 93:929-36. 2006
    b>Pancreaticoduodenectomy is the primary treatment for periampullary cancer. Associated morbidity is high and often related to pancreatic anastomotic failure...
  100. ncbi Duodenum-preserving pancreatic head resection versus pancreatoduodenectomy for surgical treatment of chronic pancreatitis: a systematic review and meta-analysis
    Markus K Diener
    Department of General, Visceral and Trauma Surgery, University of Heidelberg, Heidelberg, Germany
    Ann Surg 247:950-61. 2008
    ....
  101. ncbi Treatment guidelines for branch duct type intraductal papillary mucinous neoplasms of the pancreas: when can we operate or observe?
    Jin Young Jang
    Department of Surgery, Seoul National University College of Medicine, 28 Yongon Dong, Chongno Gu, Seoul, South Korea
    Ann Surg Oncol 15:199-205. 2008
    ..However, no definite treatment guideline (with respect to surgery or observation) has been issued on the management of branch duct type IPMN...

Research Grants13

  1. Validation of potential early diagnostic and prognostic markers for pancreatic ca
    Paul Chiao; Fiscal Year: 2007
    ..survival of patients with pancreatic cancer can be improved by using therapeutic approaches such as pancreaticoduodenectomy plus chemoradiation. The most promising approach for the early diagnosis of cancer utilizes tumor markers...
  2. CORRELATES AND TREATMENT OF PANCREATIC CARCINOMA
    Charles Yeo; Fiscal Year: 1993
    ..of patients present with incurable disease, and of those that are candidates for surgical resection by pancreaticoduodenectomy, few survive five-years...
  3. ALLOGENIC PANCREATIC TUMOR VACCINE CELL LINE
    Elizabeth Jaffee; Fiscal Year: 2003
    ..radiation and chemotherapy are only palliative with small effects on disease- free survival following pancreaticoduodenectomy. Moreover, no methods are available for primary prevention or early screening...
  4. Biomarkers of COX-2 inhibitors in intraductal papillary mucinous neoplasm (IPMN)
    Christian Schmidt; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  5. Influence of Tumor Immunogenicity to Immunotherapy
    Jeffrey Norton; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  6. INJURY TO LIVER SINUSOIDAL ENDOTHELIAL CELLS
    Steven Strasberg; Fiscal Year: 2003
    ..A potentially beneficial improvements in preservation solutions are identified they will be tested in whole isolated livers and by transplantation in the rat. ..
  7. Hepatic Arterial Flouridine and IV Bevacizumab for Primary Hepatic Malignancy
    William Jarnagin; Fiscal Year: 2008
    ..Furthermore, several important clinical issues are addressed by the proposed correlative studies, the results of which would be of broad general interest in clinical oncology. [unreadable] [unreadable] [unreadable]..
  8. Role of Somatostatin Receptors in Pancreatic Cancer
    William Fisher; Fiscal Year: 2003
    ..Since somatostatin expression has been demonstrated in other tumor types, the findings may also be relevant to other cancers. ..
  9. Increasing Functional Liver Mass in Health and Disease
    Leonidas Koniaris; Fiscal Year: 2005
    ..2) Determine the extent to which and mechanisms by which co-administrating HCF and Follistatin along with IL-6 facilitates the liver growth response and reduces IL-6 associated toxicity. ..
  10. The Role of GDF-15 in Organ Injury
    Leonidas Koniaris; Fiscal Year: 2005
    ..The completion of this mentored research training will further the candidate?s goal of applying bench-derived scientific discovery to the treatment of surgical disease as an independent investigator. ..
  11. MMP-9 mediates cerebral edema in fulminant liver failure
    Justin Nguyen; Fiscal Year: 2004
    ..2. To determine whether cerebral edema is attenuated in MMP-9 knockout mice following experimentally induced FHF. ..
  12. Tracked Laparoscopic Ultrasound for Use in Liver Surgery
    Philip Bao; Fiscal Year: 2004
    ..Ultimately, the success of this project may improve care for and expand the population who will benefit from surgical therapy of liver cancer. ..
  13. MMP-9 in Blood-Brain Barrier Failure in Fulminant Hepatic Failure
    Justin Nguyen; Fiscal Year: 2009
    ..Specific Aim 2: To determine if inhibition of MMP-9 results in an increase in survival in experimentally induced FHF. ..