sigmoidoscopy

Summary

Summary: Endoscopic examination, therapy or surgery of the sigmoid flexure.

Top Publications

  1. ncbi Screening sigmoidoscopy. Factors associated with utilization
    S F Lewis
    Department of Medicine, University of Wisconsin School of Medicine, Madison, USA
    J Gen Intern Med 11:542-4. 1996
  2. ncbi Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial
    Wendy S Atkin
    Department of Surgery and Cancer, Imperial College London, London, UK
    Lancet 375:1624-33. 2010
  3. pmc Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy
    Robert E Schoen
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    N Engl J Med 366:2345-57. 2012
  4. ncbi Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy
    L Hol
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Gut 59:62-8. 2010
  5. ncbi Once-only sigmoidoscopy in colorectal cancer screening: follow-up findings of the Italian Randomized Controlled Trial--SCORE
    Nereo Segnan
    Centro di Prevenzione Oncologica Piemonte and S Giovanni University Hospital, Turin, Italy
    J Natl Cancer Inst 103:1310-22. 2011
  6. pmc Effect of flexible sigmoidoscopy-based screening on incidence and mortality of colorectal cancer: a systematic review and meta-analysis of randomized controlled trials
    B Joseph Elmunzer
    Division of Gastroenterology and Hepatology, Department of Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
    PLoS Med 9:e1001352. 2012
  7. ncbi Acceptability and side-effects of colonoscopy and sigmoidoscopy in a screening setting
    Carlo Senore
    Centro Prevenzione Oncologica Regione Piemonte and Azienda Ospedaliero Universitaria S Giovanni Battista di Torino, V San Francesco da Paola 31, 10123 Torino, Italy
    J Med Screen 18:128-34. 2011
  8. ncbi Validity of self-reported colorectal cancer screening behavior
    M Baier
    American Medical Center Cancer Research Center, Lakewood, Colorado 80214, USA
    Cancer Epidemiol Biomarkers Prev 9:229-32. 2000
  9. ncbi Systematic review and meta-analysis of the evidence for flexible sigmoidoscopy as a screening method for the prevention of colorectal cancer
    C Littlejohn
    NHS Grampian, Institute of Applied Health Sciences, University of Aberdeen, School of Medicine and Dentistry, Foresterhill, Aberdeen, UK
    Br J Surg 99:1488-500. 2012
  10. pmc Screening colonoscopy and risk for incident late-stage colorectal cancer diagnosis in average-risk adults: a nested case-control study
    Chyke A Doubeni
    Department of Family Medicine and Community Health, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Gates 2, Philadelphia, PA 19104, USA
    Ann Intern Med 158:312-20. 2013

Detail Information

Publications329 found, 100 shown here

  1. ncbi Screening sigmoidoscopy. Factors associated with utilization
    S F Lewis
    Department of Medicine, University of Wisconsin School of Medicine, Madison, USA
    J Gen Intern Med 11:542-4. 1996
    Although screening sigmoidoscopy (SS) reduces colorectal cancer mortality, surveys indicate that fewer than half of primary care physicians routinely recommend SS and less than 10% of eligible patients receive this test...
  2. ncbi Once-only flexible sigmoidoscopy screening in prevention of colorectal cancer: a multicentre randomised controlled trial
    Wendy S Atkin
    Department of Surgery and Cancer, Imperial College London, London, UK
    Lancet 375:1624-33. 2010
    ..We tested the hypothesis that only one flexible sigmoidoscopy screening between 55 and 64 years of age can substantially reduce colorectal cancer incidence and mortality.
  3. pmc Colorectal-cancer incidence and mortality with screening flexible sigmoidoscopy
    Robert E Schoen
    Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA
    N Engl J Med 366:2345-57. 2012
    The benefits of endoscopic testing for colorectal-cancer screening are uncertain. We evaluated the effect of screening with flexible sigmoidoscopy on colorectal-cancer incidence and mortality.
  4. ncbi Screening for colorectal cancer: randomised trial comparing guaiac-based and immunochemical faecal occult blood testing and flexible sigmoidoscopy
    L Hol
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, s Gravendijkwal 230, 3015 CE Rotterdam, The Netherlands
    Gut 59:62-8. 2010
    ..We conducted a randomised trial comparing participation and detection rates (DR) per screenee of guaiac-based faecal occult blood test (gFOBT), immunochemical FOBT (FIT), and flexible sigmoidoscopy (FS) for CRC screening.
  5. ncbi Once-only sigmoidoscopy in colorectal cancer screening: follow-up findings of the Italian Randomized Controlled Trial--SCORE
    Nereo Segnan
    Centro di Prevenzione Oncologica Piemonte and S Giovanni University Hospital, Turin, Italy
    J Natl Cancer Inst 103:1310-22. 2011
    A single flexible sigmoidoscopy at around the age of 60 years has been proposed as an effective strategy for colorectal cancer (CRC) screening.
  6. pmc Effect of flexible sigmoidoscopy-based screening on incidence and mortality of colorectal cancer: a systematic review and meta-analysis of randomized controlled trials
    B Joseph Elmunzer
    Division of Gastroenterology and Hepatology, Department of Medicine, University of Michigan Medical Center, Ann Arbor, MI, USA
    PLoS Med 9:e1001352. 2012
    Randomized controlled trials (RCTs) have yielded varying estimates of the benefit of flexible sigmoidoscopy (FS) screening for colorectal cancer (CRC)...
  7. ncbi Acceptability and side-effects of colonoscopy and sigmoidoscopy in a screening setting
    Carlo Senore
    Centro Prevenzione Oncologica Regione Piemonte and Azienda Ospedaliero Universitaria S Giovanni Battista di Torino, V San Francesco da Paola 31, 10123 Torino, Italy
    J Med Screen 18:128-34. 2011
    ..Quantitative information on adverse reactions associated with colorectal cancer (CRC) screening tests is useful to estimate the balance between benefit and risk in different strategies...
  8. ncbi Validity of self-reported colorectal cancer screening behavior
    M Baier
    American Medical Center Cancer Research Center, Lakewood, Colorado 80214, USA
    Cancer Epidemiol Biomarkers Prev 9:229-32. 2000
    ..Cases who had received a fecal occult blood test (FOBT), flexible sigmoidoscopy, and/or colonoscopy, and controls who had no record of colorectal screening were identified among 40-75-year-..
  9. ncbi Systematic review and meta-analysis of the evidence for flexible sigmoidoscopy as a screening method for the prevention of colorectal cancer
    C Littlejohn
    NHS Grampian, Institute of Applied Health Sciences, University of Aberdeen, School of Medicine and Dentistry, Foresterhill, Aberdeen, UK
    Br J Surg 99:1488-500. 2012
    ..The aim of this review and meta-analysis was to determine whether flexible sigmoidoscopy (FS) is an effective population screening method for reducing mortality from colorectal cancer.
  10. pmc Screening colonoscopy and risk for incident late-stage colorectal cancer diagnosis in average-risk adults: a nested case-control study
    Chyke A Doubeni
    Department of Family Medicine and Community Health, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Gates 2, Philadelphia, PA 19104, USA
    Ann Intern Med 158:312-20. 2013
    ..The effectiveness of screening colonoscopy in average-risk adults is uncertain, particularly for right colon cancer...
  11. ncbi Measures for ascertaining use of colorectal cancer screening in behavioral, health services, and epidemiologic research
    Sally W Vernon
    Cancer Epidemiol Biomarkers Prev 13:898-905. 2004
  12. pmc Iron homeostasis and distal colorectal adenoma risk in the prostate, lung, colorectal, and ovarian cancer screening trial
    Amanda J Cross
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, Department of Health and Human Services, Rockville, MD 20852, USA
    Cancer Prev Res (Phila) 4:1465-75. 2011
    ....
  13. ncbi Perceived barriers to flexible sigmoidoscopy screening for colorectal cancer among UK ethnic minority groups: a qualitative study
    K L Austin
    UCL Health Behaviour Research Centre, Department of Epidemiology and Public Health, 1 19 Torrington Place, London WC1E 6BT, UK
    J Med Screen 16:174-9. 2009
    ..The aim of this study was to explore barriers to the uptake of flexible sigmoidoscopy (FS) screening among UK ethnic minority populations...
  14. ncbi [S3-Guidelines Conference "Colorectal Carcinoma" 2004]
    W Schmiegel
    Ruhr Universitat Bochum, Medizinische Universitatsklinik
    Z Gastroenterol 42:1129-77. 2004
  15. pmc Risk of colorectal cancer seven years after flexible sigmoidoscopy screening: randomised controlled trial
    Geir Hoff
    Norwegian Colorectal Cancer Prevention NORCCAP Centre, Cancer Registry of Norway, Montebello, NO 0310 Oslo, Norway
    BMJ 338:b1846. 2009
    To determine the risk of colorectal cancer after screening with flexible sigmoidoscopy.
  16. ncbi Colorectal cancer screening knowledge, attitudes, and beliefs among veterans: does literacy make a difference?
    Nancy C Dolan
    Midwest Center for Health Services and Policy Research, VA Chicago Healthcare System, Department of Medicine, Feinberg School of Medicine, Robert H Lurie Comprehensive Cancer Center, Northwestern University, Chicago, IL 60611, USA
    J Clin Oncol 22:2617-22. 2004
    ..To evaluate whether lower literacy is associated with poorer knowledge and more negative attitudes and beliefs toward colorectal cancer screening among veterans without recent colorectal cancer screening...
  17. ncbi American Cancer Society guidelines for the early detection of cancer
    Robert A Smith
    Cancer Control Department, American Cancer Society, Atlanta, GA, USA
    CA Cancer J Clin 52:8-22. 2002
    ....
  18. ncbi Which colon cancer screening test? A comparison of costs, effectiveness, and compliance
    S Vijan
    The Veterans Affairs Center for Practice Management and Outcomes Research, Ann Arbor, Michigan 48113 0170, USA
    Am J Med 111:593-601. 2001
    ..is expensive compared with other screening modalities, such as fecal occult blood testing and flexible sigmoidoscopy. We sought to determine the cost effectiveness of different screening strategies for colorectal cancer at ..
  19. ncbi Comparison of CT colonography, colonoscopy, sigmoidoscopy and faecal occult blood tests for the detection of advanced adenoma in an average risk population
    A Graser
    Department of Clinical Radiology, University of Munich, Klinikum Grosshadern, Munich, Germany
    Gut 58:241-8. 2009
    ..screening tests in parallel for the detection of advanced colonic neoplasia: CT colonography (CTC), colonoscopy (OC), flexible sigmoidoscopy (FS), faecal immunochemical stool testing (FIT) and faecal occult blood testing (FOBT).
  20. ncbi A prospective randomized trial comparing a virtual reality simulator to bedside teaching for training in sigmoidoscopy
    L B Gerson
    Division of Gastroenterology and Hepatology, Stanford University School of Medicine, Stanford, California 94305, USA
    Endoscopy 35:569-75. 2003
    ..A prospective randomized trial was conducted to compare the exclusive use of a virtual reality endoscopy simulator with bedside teaching for training in sigmoidoscopy.
  21. ncbi Colorectal cancer screening for persons at average risk
    William F Anderson
    Division of Cancer Prevention Gastrointestinal and Other Cancer Research Group, National Cancer Institute, Bethesda, MD 20892 7117, USA
    J Natl Cancer Inst 94:1126-33. 2002
  22. ncbi Stool screening for colorectal cancer: evolution from occult blood to molecular markers
    David A Ahlquist
    Division of Gastroenterology and Hepatology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Clin Chim Acta 315:157-68. 2002
    ..Participation rates for colorectal cancer screening remain low due, in part, to perceived discomfort, potential harm, and high costs with available tools...
  23. ncbi Risk of proximal and distal colorectal cancer following flexible sigmoidoscopy: a population-based cohort study
    Linda Rabeneck
    Department of Medicine, Management and Evaluation, University of Toronto, Toronto, Canada
    Am J Gastroenterol 103:2075-82. 2008
    Little is known about the risk of proximal and distal colorectal cancer (CRC) following flexible sigmoidoscopy (FS) in usual clinical practice...
  24. ncbi Utilization of lower gastrointestinal endoscopy and fecal occult blood test in 11 European countries: evidence from the Survey of Health, Aging and Retirement in Europe (SHARE)
    C Stock
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center DKFZ, Heidelberg, Germany
    Endoscopy 42:546-56. 2010
    Lower gastrointestinal endoscopy (sigmoidoscopy and colonoscopy) and the fecal occult blood test (FOBT) are thought to impact on colorectal cancer incidence and mortality...
  25. ncbi Rethinking patient satisfaction: patient experiences of an open access flexible sigmoidoscopy service
    A Dougall
    Department of Anthropology, University of Durham, UK
    Soc Sci Med 50:53-62. 2000
    ..The evidence from this research will be used to argue that standard consumer satisfaction questionnaires of health provision are inadequate indicators of patients' experience of health care delivery...
  26. ncbi Declining the offer of flexible sigmoidoscopy screening for bowel cancer: a qualitative investigation of the decision-making process
    K McCaffery
    Department of Epidemiology and Public Health, Royal Free and University College Medical School, London, UK
    Soc Sci Med 53:679-91. 2001
    ..were used to investigate decision-making among a group of older adults who declined the offer of flexible sigmoidoscopy screening for bowel cancer...
  27. pmc Cost-effectiveness of colorectal cancer screening - an overview
    Iris Lansdorp-Vogelaar
    Department of Public Health, Erasmus MC, University Medical Center, PO Box 2040, 3000 CA Rotterdam, The Netherlands
    Best Pract Res Clin Gastroenterol 24:439-49. 2010
    ..There is consensus that the new technologies of stool DNA testing, computed tomographic colonography and capsule endoscopy are not yet cost-effective compared with the established CRC screening tests...
  28. ncbi The topography of colorectal cancer varies by race/ethnicity and affects the utility of flexible sigmoidoscopy
    C P Theuer
    Department of Surgery, University of California, Irvine 92697-7550, USA
    Am Surg 67:1157-61. 2001
    ..Americans considered at "average" risk for the development of colorectal cancer either with flexible sigmoidoscopy and fecal occult blood testing (FOBT) or with colonoscopy...
  29. ncbi Colorectal cancer screening comparing no screening, immunochemical and guaiac fecal occult blood tests: a cost-effectiveness analysis
    Leo G M van Rossum
    Department of Epidemiology, Biostatistics and HTA, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
    Int J Cancer 128:1908-17. 2011
    ..I-FOBT also dominated in sensitivity analyses, varying uncertainty surrounding important effect and cost parameters. CRC screening with I-FOBT dominated G-FOBT and no screening with or without accounting for uncertainty...
  30. ncbi Assessment of the multiple components of the variability in the adenoma detection rate in sigmoidoscopy screening, and lessons for training
    M Fracchia
    Gastroenterology Unit, Mauriziano Umberto I Hospital, Turin, Italy
    Endoscopy 42:448-55. 2010
    ..The determinants of the observed variability of adenoma detection rate (ADR) in endoscopy screening have not yet been fully explained...
  31. ncbi Healthcare system factors and colorectal cancer screening
    Jane G Zapka
    Medical School, University of Massachusetts, Worcester 01655, USA
    Am J Prev Med 23:28-35. 2002
    ..Developing effective programs to promote colorectal cancer (CRC) screening requires understanding of the effect of healthcare system factors on access to screening and adherence to guidelines...
  32. pmc Variation in folate pathway genes and distal colorectal adenoma risk: a sigmoidoscopy-based case-control study
    A Joan Levine
    Department of Preventive Medicine, Genetic Epidemiology, University of Southern California Keck School of Medicine, Los Angeles, CA 90033, USA
    Cancer Causes Control 22:541-52. 2011
    ..Folate-associated one-carbon metabolism (FOCM) is an important pathway in colorectal neoplasia risk but data on genetic variation in this pathway are largely limited to studies of single SNPs in selected genes...
  33. ncbi Dietary fibre and colorectal adenoma in a colorectal cancer early detection programme
    Ulrike Peters
    Nutritional Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, US National Institutes of Health, DHHS, MD 20892 7273, USA
    Lancet 361:1491-5. 2003
    ..Although dietary fibre has been reported to have no association with colorectal adenoma and cancer, in some studies this topic remains controversial...
  34. ncbi Flexible sigmoidoscopy in the PLCO cancer screening trial: results from the baseline screening examination of a randomized trial
    Joel L Weissfeld
    University of Pittsburgh Cancer Institute, Pittsburgh, PA, USA
    J Natl Cancer Inst 97:989-97. 2005
    ..is a randomized clinical trial to test the effectiveness of cancer screening, including the effect of flexible sigmoidoscopy screening on colorectal cancer mortality...
  35. ncbi Asia Pacific consensus recommendations for colorectal cancer screening
    J J Y Sung
    The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong
    Gut 57:1166-76. 2008
    ..Faecal occult blood test (FOBT, guaiac-based and immunochemical tests), flexible sigmoidoscopy and colonoscopy are recommended for CRC screening...
  36. pmc Underuse of screening sigmoidoscopy and colonoscopy in a large cohort of US adults
    Ann Chao
    Epidemiology and Surveillance Research, American Cancer Society, 1599 Clifton Road NE, Atlanta, GA 30329 4251, USA
    Am J Public Health 94:1775-81. 2004
    We examined the prevalence of endoscopy (sigmoidoscopy or colonoscopy) by indication and by demographic and lifestyle factors.
  37. ncbi Persistent racial and ethnic disparities in up-to-date colorectal cancer testing in medicare enrollees
    Joshua J Fenton
    Department of Family and Community Medicine, School of Medicine, University of California, Davis, Sacramento, California 95817, USA
    J Am Geriatr Soc 57:412-8. 2009
    ....
  38. ncbi Computed tomography-based high-dose-rate intracavitary brachytherapy for uterine cervical cancer: preliminary demonstration of correlation between dose-volume parameters and rectal mucosal changes observed by flexible sigmoidoscopy
    Woong Sub Koom
    Research Institute and Hospital, National Cancer Center, Goyang, Gyeonggi, South Korea
    Int J Radiat Oncol Biol Phys 68:1446-54. 2007
    To compare the dose-volume histogram (DVH) parameters obtained by three-dimensional gynecologic brachytherapy planning with the rectosigmoid mucosal changes observed by flexible sigmoidoscopy.
  39. ncbi Delayed-release oral mesalamine 4.8 g/day (800-mg tablet) is effective for patients with moderately active ulcerative colitis
    William J Sandborn
    Inflammatory Bowel Disease Clinic, Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA
    Gastroenterology 137:1934-43.e1-3. 2009
    ..This study was conducted to determine the efficacy and safety of mesalamine 4.8 g/day compared with 2.4 g/day for the treatment of moderately active UC...
  40. ncbi Potential for colorectal cancer prevention of sigmoidoscopy versus colonoscopy: population-based case control study
    Hermann Brenner
    Department of Epidemiology, German Cancer Research Center, Bergheimer Strasse 20, D 69115 Heidelberg, Germany
    Cancer Epidemiol Biomarkers Prev 16:494-9. 2007
    We aimed to estimate the proportions of colorectal cancer cases that might be prevented by sigmoidoscopy compared with colonoscopy among women and men...
  41. pmc Primary care, economic barriers to health care, and use of colorectal cancer screening tests among Medicare enrollees over time
    Chyke A Doubeni
    Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Ann Fam Med 8:299-307. 2010
    ..The objective of this study was to examine the impact of primary care and economic barriers to health care on CRC testing relative to the 2001 Medicare expansion of screening coverage...
  42. ncbi Colon pathology detected after a positive screening flexible sigmoidoscopy: a prospective study in an ethnically diverse cohort
    Fritz Francois
    Department of Medicine and Division of Gastroenterology, VA New York Harbor Healthcare System and New York University School of Medicine, New York, New York 10010, USA
    Am J Gastroenterol 101:823-30. 2006
    Although the association between distal neoplasia on sigmoidoscopy and proximal colonic pathology on follow-up colonoscopy has been well-described, it is not known if these findings are consistent across ethnic groups...
  43. ncbi A 9-year follow-up study of participants and nonparticipants in sigmoidoscopy screening: importance of self-selection
    Johannes Blom
    Division of Surgery, Department for Clinical Science, Intervention and Technology, Karolinska Institutet at Karolinska University Hospital, K53, Huddinge, 141 86 Stockholm, Sweden
    Cancer Epidemiol Biomarkers Prev 17:1163-8. 2008
    ..Self-selection may compromise cost-effectiveness of screening programs. We hypothesized that nonparticipants have generally higher morbidity and mortality than participants...
  44. ncbi Cost-effectiveness of colorectal cancer screening: comparison of community-based flexible sigmoidoscopy with fecal occult blood testing and colonoscopy
    Beth A O'Leary
    The Lewin Group, a Division of Quintiles Australia, Sydney, New South Wales, Australia
    J Gastroenterol Hepatol 19:38-47. 2004
    To determine the cost-effectiveness of screening for colorectal cancer using flexible sigmoidoscopy once every 10 years, compared with annual and biennial rehydrated Hemoccult fecal occult blood testing and colonoscopy once every 10 ..
  45. ncbi Colonoscopic screening of average-risk women for colorectal neoplasia
    Philip Schoenfeld
    Division of Gastroenterology, University of Michigan School of Medicine and Veterans Affairs Center for Excellence in Health Services Research, Ann Arbor 48105, USA
    N Engl J Med 352:2061-8. 2005
    ..villous adenomas, adenomas with high-grade dysplasia, or cancer) in men would be missed with the use of flexible sigmoidoscopy but detected by colonoscopy. In a tandem study, we examined the yield of screening colonoscopy in women.
  46. ncbi Screening for colorectal cancer in average-risk Chinese population using a mixed strategy with sigmoidoscopy and colonoscopy
    Jyh Ming Liou
    Department of Internal Medicine, National Taiwan University Hospital, National Taiwan University College of Medicine, No 7, Chung Shan S Road, Taipei, Taiwan
    Dis Colon Rectum 50:630-40. 2007
    ..This study was designed to evaluate the efficacy of the mixed screening strategy with sigmoidoscopy and colonoscopy in the average-risk Chinese population.
  47. pmc Effect of screening sigmoidoscopy and screening colonoscopy on colorectal cancer incidence and mortality: systematic review and meta-analysis of randomised controlled trials and observational studies
    Hermann Brenner
    Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, INF 581, 69120 Heidelberg, Germany German Cancer Consortium, Heidelberg, Germany
    BMJ 348:g2467. 2014
    To review, summarise, and compare the evidence for effectiveness of screening sigmoidoscopy and screening colonoscopy in the prevention of colorectal cancer occurrence and deaths.
  48. ncbi Screening for colorectal neoplasms with new fecal occult blood tests: update on performance characteristics
    James E Allison
    Division of Research, Kaiser Permanente Northern California Region, 2000 Broadway, Oakland, CA 94612 2304, USA
    J Natl Cancer Inst 99:1462-70. 2007
    ..Thus, improving the sensitivity of FOBT should make colon cancer screening programs that use these tests more effective...
  49. pmc Uptake of population-based flexible sigmoidoscopy screening for colorectal cancer: a nurse-led feasibility study
    Hannah Brotherstone
    Cancer Research UK Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, London WC1E 6BT, UK
    J Med Screen 14:76-80. 2007
    To assess uptake of once-only flexible sigmoidoscopy (FS) in a community sample to determine whether FS would be viable as a method of population-based screening for colorectal cancer.
  50. ncbi Disparities despite coverage: gaps in colorectal cancer screening among Medicare beneficiaries
    Ann S O'Malley
    Cancer Control Program, Georgetown University Medical Center, Washington, DC, USA
    Arch Intern Med 165:2129-35. 2005
    ..Despite its effectiveness in reducing mortality, colorectal cancer (CRC) screening rates are low, especially among low-income and minority groups; however, physician recommendation can increase screening rates...
  51. ncbi Colorectal cancer screening in asymptomaic adults: comparison of colonoscopy, sigmoidoscopy and fecal occult blood tests
    Tsun I Cheng
    Department of Medicine, Koo Foundation Sun Yat Sen Cancer Center, Taipei, Taiwan
    J Formos Med Assoc 101:685-90. 2002
    Fecal occult blood tests (FOBT) and flexible sigmoidoscopy have previously been recommended for colon cancer screening...
  52. ncbi Racial disparities in the use of and indications for colorectal procedures in Medicare beneficiaries
    Gregory S Cooper
    Division of Gastroenterology, University Hospitals of Cleveland, 11100 Euclid Avenue, Cleveland, OH 44106 5066, USA
    Cancer 100:418-24. 2004
    ..African Americans are diagnosed more frequently with colorectal carcinoma at a later stage compared with Caucasians. One potential reason for the disparity is a lower rate of screening examinations...
  53. pmc Protective effect of faecal occult blood test screening for colorectal cancer: worse prognosis for screening refusers
    Y Niv
    Department of Gastroenterology, Rabin Medical Center, Beilinson Campus, Tel Aviv University, Israel
    Gut 50:33-7. 2002
    ..We tested the hypothesis that individuals offered FOBT screening but refused would have an increased incidence and worse prognosis for CRC compared with those tested and with controls...
  54. ncbi Predicting adherence to colonoscopy or flexible sigmoidoscopy on the basis of physician appointment-keeping behavior
    Barbara J Turner
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
    Ann Intern Med 140:528-32. 2004
    Poor patient attendance to scheduled flexible sigmoidoscopy or colonoscopy may contribute to deficient colorectal cancer screening.
  55. pmc Cost-effectiveness of population-based screening for colorectal cancer: a comparison of guaiac-based faecal occult blood testing, faecal immunochemical testing and flexible sigmoidoscopy
    L Sharp
    National Cancer Registry Ireland, Cork Airport Business Park, Building 6800, Kinsale Road, Cork, Ireland
    Br J Cancer 106:805-16. 2012
    ..Ireland based on (i) biennial guaiac-based faecal occult blood testing (gFOBT) at ages 55-74, with reflex faecal immunochemical testing (FIT); (ii) biennial FIT at ages 55-74; and (iii) once-only flexible sigmoidoscopy (FSIG) at age 60.
  56. pmc Patient preferences for colon cancer screening
    M Pignone
    Division of General Internal Medicine, University of North Carolina School of Medicine, Chapel Hill 27599-7110, USA
    J Gen Intern Med 14:432-7. 1999
    ..preferences for four different screening strategies: annual fecal occult blood testing (FOBT) alone; flexible sigmoidoscopy (FSIG) every 5 years alone; both annual FOBT and FSIG every 5 years; or no screening. DESIGN: Survey...
  57. ncbi Test performance of immunologic fecal occult blood testing and sigmoidoscopy compared with primary colonoscopy screening for colorectal advanced adenomas
    Carolina A J Khalid-de Bakker
    Division of Gastroenterology Hepatology, Department of Internal Medicine, Maastricht University Medical Center, The Netherlands
    Cancer Prev Res (Phila) 4:1563-71. 2011
    ..Advanced adenomas were detected in 38 (11.6%) of 329 subjects. Sensitivity for advanced adenomas of FIT and sigmoidoscopy were 15.8% (95% CI: 6.0-31.3) and 73.7% (95% CI: 56.9-86.6), respectively...
  58. ncbi What influences the decision to participate in colorectal cancer screening with faecal occult blood testing and sigmoidoscopy?
    L van Dam
    Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre Rotterdam, The Netherlands
    Eur J Cancer 49:2321-30. 2013
    ..Uptake is an important determinant of the effectiveness of population-based screening. Uptake of colorectal cancer (CRC) screening generally remains sub-optimal...
  59. ncbi Gender differences in utilization of colorectal cancer screening
    J Wardle
    Health Behaviour Unit Cancer Research UK, Department of Epidemiology and Public Health, University College London, UK
    J Med Screen 12:20-7. 2005
    To assess the demographic and psychological mediators of gender differences in uptake of flexible sigmoidoscopy (FS) screening for colorectal cancer.
  60. ncbi Exposure to colorectal examinations before a colorectal cancer diagnosis: a case-control study
    Sanna A Mulder
    Department of Gastroenterology and Hepatology, Erasmus University Medical Center, Rotterdam, s Gravendijkwal 230, Rotterdam 3015 CE, The Netherlands
    Eur J Gastroenterol Hepatol 22:437-43. 2010
    ....
  61. ncbi Risk of colorectal cancer after colonoscopy compared with flexible sigmoidoscopy or no lower endoscopy among older patients in the United States, 1998-2005
    Yize R Wang
    Cooper Digestive Health Institute, Mount Laurel, NJ 08054, USA
    Mayo Clin Proc 88:464-70. 2013
    To determine whether the risk of colorectal cancer (CRC) decreases after colonoscopy compared with sigmoidoscopy or no lower endoscopy.
  62. pmc Testing for faecal calprotectin (PhiCal) in the Norwegian Colorectal Cancer Prevention trial on flexible sigmoidoscopy screening: comparison with an immunochemical test for occult blood (FlexSure OBT)
    G Hoff
    The Cancer Registry of Norway, Montebello, N 0310 Oslo, Norway
    Gut 53:1329-33. 2004
    ..In search for improved non-invasive tests for screening, we compared a test for faecal calprotectin (PhiCal) with a human haemoglobin immunochemical FOBT (FlexSure OBT)...
  63. ncbi Cost-effectiveness of screening for colorectal cancer in the general population
    A L Frazier
    Channing Laboratory, 181 Longwood Ave, Boston, MA 02115, USA
    JAMA 284:1954-61. 2000
    ..A recent expert panel recommended that persons at average risk of colorectal cancer (CRC) begin screening for CRC at age 50 years using 1 of several strategies. However, many aspects of different CRC screening strategies remain uncertain...
  64. pmc Flexible sigmoidoscopy and the changing distribution of colorectal cancer: implications for screening
    K McCallion
    Department of Surgery, Royal Victoria Hospital, Queen s University of Belfast, Belfast, UK
    Gut 48:522-5. 2001
    ..The aim of this study was to investigate the potential implications of this proximal shift in CRC distribution on the efficacy of flexible sigmoidoscopy (FS) as a screening tool.
  65. ncbi Comparative effectiveness and cost-effectiveness of screening colonoscopy vs. sigmoidoscopy and alternative strategies
    Ravi N Sharaf
    Department of Gastroenterology, Department of Medicine, Hofstra University School of Medicine, North Shore Long Island Jewish Health System, Manhasset, NY, USA
    Am J Gastroenterol 108:120-32. 2013
    Fecal occult blood testing (FOBT) and sigmoidoscopy are proven to decrease colorectal cancer (CRC) incidence and mortality. Sigmoidoscopy's benefit is limited to the distal colon...
  66. pmc Does informed consent alter elderly patients' preferences for colorectal cancer screening? Results of a randomized trial
    A M Wolf
    Department of Medicine, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    J Gen Intern Med 15:24-30. 2000
    ..To assess the impact of informed consent on elderly patients' colorectal cancer (CRC) screening preferences...
  67. ncbi Colorectal cancer screening with flexible sigmoidoscopy-participants' experiences and technical feasibility
    J Blom
    Division of Surgery, Karolinska Institutet at Huddinge University Hospital, Stockholm, Sweden
    Eur J Surg Oncol 30:362-9. 2004
    To evaluate tolerability and technical feasibility of colorectal cancer screening with flexible sigmoidoscopy.
  68. ncbi Flexible sigmoidoscopy for colorectal cancer screening in the elderly
    Ajay Pabby
    Section of Gastroenterology, Boston University School of Medicine, 85 East Concord Street, Boston, Massachusetts 02118, USA
    Dig Dis Sci 50:2147-52. 2005
    Data on performance characteristics of flexible sigmoidoscopy (FS) between age groups are limited...
  69. ncbi A sigmoidoscopy-based case-control study of polyps: macronutrients, fiber and meat consumption
    R W Haile
    Department of Preventive Medicine, USC School of Medicine, University of Southern California, Los Angeles 90033 0800, USA
    Int J Cancer 73:497-502. 1997
    We conducted a large, sigmoidoscopy-based case-control study to examine the relation of intake of macronutrients, meat, and fiber to occurrence of adenomas of the large bowel...
  70. ncbi Colorectal cancer (CRC) screening using sigmoidoscopy followed by colonoscopy: a feasibility and efficacy study on a cancer institute based population
    H Bleiberg
    Gastroenterology Department and Epidemiology Clinic, Jules Bordet Institute, Brussels, Belgium
    Ann Oncol 17:1328-32. 2006
    Advanced distal neoplasia found at sigmoidoscopy could be the marker for more proximal lesions.
  71. ncbi Female gender and other factors predictive of a limited screening flexible sigmoidoscopy examination for colorectal cancer
    Mohamad A Eloubeidi
    Division of Gastroenterology and Hepatology, The University of Alabama at Birmingham, Birmingham, Alabama 35294, USA
    Am J Gastroenterol 98:1634-9. 2003
    Flexible sigmoidoscopy (FS) screening for colorectal cancer (CRC) is associated with reduced mortality from CRC...
  72. ncbi One-time screening for colorectal cancer with combined fecal occult-blood testing and examination of the distal colon
    D A Lieberman
    Veterans Affairs Medical Center in Portland, OR 97207, USA
    N Engl J Med 345:555-60. 2001
    Fecal occult-blood testing and sigmoidoscopy have been recommended for screening for colorectal cancer, but the sensitivity of such combined testing for detecting neoplasia is uncertain...
  73. ncbi Screening flexible sigmoidoscopy: patient attitudes and compliance
    B D McCarthy
    Evans Department of Clinical Research, University Hospital, Boston University Medical Center, Massachusetts
    J Gen Intern Med 8:120-5. 1993
    OBJECTIVE: To measure patients' expectations and attitudes about screening flexible sigmoidoscopy and their discomfort during the procedure, and to identify factors affecting compliance among patients scheduled for sigmoidoscopy...
  74. ncbi Why hasn't this patient been screened for colon cancer? An Iowa Research Network study
    Barcey T Levy
    Department of Family Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City 52242, USA
    J Am Board Fam Med 20:458-68. 2007
    ..The objective of this study was to describe physicians' reasons for screening or not screening specific patients for CRC and their approach to CRC testing discussions...
  75. ncbi Development of a flexible sigmoidoscopy training program for rural nurse practitioners and physician assistants to increase colorectal cancer screening among Alaska Native people
    Diana Redwood
    Alaska Native Epidemiology Center, Alaska Native Tribal Health Consortium, Anchorage, AK 99508, USA
    J Health Care Poor Underserved 20:1041-8. 2009
    ..Anchorage, colorectal cancer screening rates improved dramatically with the initiation of a dedicated flexible sigmoidoscopy screening program staffed by mid-level providers...
  76. pmc Quality in the technical performance of screening flexible sigmoidoscopy: recommendations of an international multi-society task group
    T R Levin
    Kaiser Permanente Division of Research, 2000 Broadway, 2nd Floor, Oakland, CA 94612, USA
    Gut 54:807-13. 2005
    Flexible sigmoidoscopy (FS) is a complex technical procedure performed in a variety of settings, by examiners with diverse professional backgrounds, training, and experience...
  77. ncbi Meat intake, cooking-related mutagens and risk of colorectal adenoma in a sigmoidoscopy-based case-control study
    Marc J Gunter
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, EPS, 6120 Executive Boulevard, Rockville, MD 20852, USA
    Carcinogenesis 26:637-42. 2005
    ..49 (95% CI, 0.28-0.85)]. We did not identify any association with consumption of individual HCAs and colorectal adenoma risk. These results support the hypothesis that BP contributes to colorectal carcinogenesis...
  78. ncbi Cost effectiveness and projected national impact of colorectal cancer screening in France
    C Hassan
    Digestive Endoscopy Unit, Catholic University, Rome, Italy
    Endoscopy 43:780-93. 2011
    ..Although immunochemical fecal tests (FIT) and guaiac-based fecal occult blood tests (g-FOBT) have been shown to be cost-effective in France, cost-effectiveness of endoscopic screening has not yet been addressed...
  79. ncbi Improving access to colorectal cancer screening through medical philanthropy: feasibility of a flexible sigmoidoscopy health fair for uninsured patients
    B Joseph Elmunzer
    Division of Gastroenterology, Department of Internal Medicine, University of Michigan Medical Center, Ann Arbor, 48109, USA
    Am J Gastroenterol 106:1741-6. 2011
    ..that the medical philanthropy platform may be effective in improving access to CRC screening, we aimed to demonstrate the feasibility of a flexible sigmoidoscopy (FS)-based CRC screening "health fair" for uninsured patients.
  80. ncbi The role of sigmoidoscopy and rectal biopsy in diagnosis and management of inflammatory bowel disease: personal experience
    S E Fochios
    Department of Medicine, Lenox Hill Hospital, New York, New York
    Am J Gastroenterol 83:114-9. 1988
    Conventional sigmoidoscopy and rectal biopsy are very useful in the diagnosis, differential diagnosis, and management of inflammatory bowel disease...
  81. ncbi A prospective national study on colonoscopy and sigmoidoscopy in 2000 in France
    Jean Marc Canard
    Centre Médico Chirurgical du Trocadéro, Paris
    Gastroenterol Clin Biol 29:17-22. 2005
    The aim of this study was to evaluate the practice of colonoscopy and sigmoidoscopy in France in 2000.
  82. ncbi [Screening for colorectal cancer by endoscopy: rectosigmoidoscopy or coloscopy?]
    M Adler
    Service de Gastro Entérologie Médicale, Hopital Erasme, U L B
    Rev Med Brux 22:A210-3. 2001
    ..However, consensus is lacking about the type of screening test. Flexible sigmoidoscopy followed by colonoscopy in the presence of adenoma(s), detect 70% of the neoplasms and should be recommended ..
  83. ncbi Costs of flexible sigmoidoscopy screening for colorectal cancer in the United Kingdom
    David K Whynes
    School of Economics, University of Nottingham, UK
    Int J Technol Assess Health Care 19:384-95. 2003
    ..Amongst the many possible protocols is once-only screening by means of flexible sigmoidoscopy. This protocol is currently being investigated in a UK multicenter trial and the study provides estimates of ..
  84. ncbi Factors associated with colon cancer screening: the role of patient factors and physician counseling
    Christina C Wee
    Division of General Medicine and Primary Care, Beth Israel Deaconess Medical Center, Harvard Medical School, Rose 115, Boston, MA 02215, USA
    Prev Med 41:23-9. 2005
    ..The prevalence of colon cancer screening is nationally low. The relative contribution of patient factors and physician counseling patterns to the low prevalence of screening is unclear...
  85. ncbi Screening for colorectal cancer with flexible sigmoidoscopy: is a 5-yr interval appropriate? A comparison of the detection of neoplasia 3 yr versus 5 yr after a normal examination
    Carol A Burke
    Department of Gastroenterology and Hepatology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am J Gastroenterol 101:1329-32. 2006
    The recommended interval for colorectal cancer screening with flexible sigmoidoscopy (FS) was recently lengthened from 3 to 5 yr. Direct evidence supporting the longer interval is lacking...
  86. ncbi Yield of advanced adenoma and cancer based on polyp size detected at screening flexible sigmoidoscopy
    Robert E Schoen
    Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvani 15213 2582, USA
    Gastroenterology 131:1683-9. 2006
    ..To examine the yield at colonoscopy when a given size lesion is observed, we assessed the yield of advanced adenoma and cancer at colonoscopy based on the size of the abnormality detected at flexible sigmoidoscopy (FSG).
  87. ncbi Prevalence of proximal adenomas after an adenoma is found on flexible sigmoidoscopy
    Kevin O'Brien
    Division of General Internal Medicine, Wilford Hall Medical Center, San Antonio, TX, USA
    Cancer Detect Prev 27:259-65. 2003
    Adenomatous polyps are a precursor of colorectal cancer and a frequent finding on screening flexible sigmoidoscopy (FS)...
  88. pmc Grading of distal colorectal adenomas as predictors for proximal colonic neoplasia and choice of endoscope in population screening: experience from the Norwegian Colorectal Cancer Prevention study (NORCCAP)
    G Gondal
    The Cancer Registry of Norway, Institute of Population Based Cancer Research, Montebello, Oslo, Norway
    Gut 52:398-403. 2003
    The purpose of this study was to evaluate the utility of easily measured clinical variables at flexible sigmoidoscopy (FS) screening that might predict a proximal advanced neoplasm (PAN).
  89. ncbi The incidence of colorectal cancer following a negative screening sigmoidoscopy: implications for screening interval
    V Paul Doria-Rose
    Department of Epidemiology, University of Washington, Seattle, Washington, USA
    Gastroenterology 127:714-22. 2004
    Current guidelines recommend a 5-year interval for colorectal cancer (CRC) screening by sigmoidoscopy. However, the optimal screening interval is uncertain...
  90. ncbi A prospective randomized single blind trial of Fleet phosphate enema versus glycerin suppositories as preparation for flexible sigmoidoscopy
    D Underwood
    Department of Surgery, Altnagelvin Area Hospital, Glenshane Road, Londonderry BT47 6SB, Northern Ireland, UK
    Ir J Med Sci 179:113-8. 2010
    This study compared the efficacy and patient acceptability of two methods of bowel preparation for flexible sigmoidoscopy.
  91. ncbi Clinical significance of small polyps found during screening with flexible sigmoidoscopy
    Francis A Farraye
    Section of Gastroenterology, Boston Medical Center, Boston University School of Medicine, Massachusetts 02118, USA
    Gastrointest Endosc Clin N Am 12:41-51. 2002
    ..strategies is beyond the scope of this article, rigorous comparisons by other authors have suggested that a sigmoidoscopy-based approach is more cost-effective than a colonoscopy-based approach...
  92. ncbi Prospective, randomized, single-blind comparison of two preparations for screening flexible sigmoidoscopy
    E J Bini
    Department of Medicine, Division of Gastroenterology, VA New York Harbor Healthcare System, New York, New York 10010, USA
    Gastrointest Endosc 52:218-22. 2000
    The best and most cost-effective bowel cleansing regimen for patients undergoing flexible sigmoidoscopy is not known...
  93. ncbi Value of fentanyl in flexible sigmoidoscopy
    Sanjoy Basu
    Endoscopy Unit, St Mary s Hospital, PO30 5TG Isle of Wight, UK
    World J Surg 28:930-4. 2004
    Studies have recorded significant patient discomfort during flexible sigmoidoscopy when it is performed without sedation/analgesia...
  94. ncbi Implementation of on-site screening sigmoidoscopy positively influences utilization by primary care providers
    P C Schroy
    Department of Medicine, Boston Medical Center, Boston, Massachusetts, USA
    Gastroenterology 117:304-11. 1999
    b>Sigmoidoscopy is an effective screening strategy for colorectal cancer that is not widely used by primary care providers...
  95. ncbi Predicting advanced proximal colonic neoplasia with screening sigmoidoscopy
    T R Levin
    Division of Research, Kaiser Permanente Medical Care Program, Oakland, Calif, USA
    JAMA 281:1611-7. 1999
    Indications are not well defined for follow-up colonoscopy for all patients with distal colonic tubular adenomas (TAs) found at screening sigmoidoscopy.
  96. ncbi Variability in flexible sigmoidoscopy performance among examiners in a screening trial
    Paul F Pinsky
    Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    Clin Gastroenterol Hepatol 3:792-7. 2005
    The efficacy of flexible sigmoidoscopy (FSG) in reducing colorectal cancer mortality is being evaluated in randomized trials. In 2 European trials, wide variability across examiners in FSG performance was noted...
  97. ncbi A randomized trial comparing three methods of bowel preparation for flexible sigmoidoscopy
    E Osgard
    Department of Internal Medicine, Madigan Army Medical Center, Tacoma, Washington, USA
    Am J Gastroenterol 93:1126-30. 1998
    The aim of this study was to assess the optimum method of bowel preparation for flexible sigmoidoscopy.
  98. ncbi Is there a role for sigmoidoscopy in symptomatic patients? Analysis of a study correlating distal and proximal colonic neoplasias detected by colonoscopy in a symptomatic population
    Vítor Binda
    Departamento de Gastroenterologia, Fundacao Faculdade Federal de Ciencias Medicas de Porto Alegre
    Arq Gastroenterol 44:2-7. 2007
    ..However, its availability is limited in developing countries. Sigmoidoscopy has been advocated as a first procedure in colorectal cancer screening strategies, in order to select those ..
  99. ncbi Inter-endoscopist variation in polyp and neoplasia pick-up rates in flexible sigmoidoscopy screening for colorectal cancer
    M Bretthauer
    NORCCAP Centres of Telemark Hospital, Skien, Norway
    Scand J Gastroenterol 38:1268-74. 2003
    The Norwegian Colorectal Cancer Prevention study is an ongoing flexible sigmoidoscopy (FS) screening trial for colorectal cancer...
  100. ncbi MTHFR (C677T and A1298C) polymorphisms and risk of sporadic distal colorectal adenoma in the UK Flexible Sigmoidoscopy Screening Trial (United Kingdom)
    Panagiota N Mitrou
    Dunn Human Nutrition Unit, MRC Wellcome Trust Building, Hills Road, Cambridge, CB2 2XY, UK
    Cancer Causes Control 17:793-801. 2006
    ..The purpose of this study was to further evaluate the role of low activity MTHFR variants as well as to explore interactive effects between alcoholic drink consumption and MTHFR variants and risk of distal colorectal adenomatous polyps...
  101. ncbi Use of flexible sigmoidoscopy to screen for colorectal cancer in HIV-infected patients 50 years of age and older
    Edmund J Bini
    Division of Gastroenterology, Veterans Affairs New York Harbor Healthcare System, 423 E 23rd Street, New York, NY 10010, USA
    Arch Intern Med 166:1626-31. 2006
    ..The aim of this study was to determine the utility of screening flexible sigmoidoscopy in patients with HIV.

Research Grants67

  1. Increasing Colon Cancer Screening in Primary Care
    Ronald Myers; Fiscal Year: 2004
    ..that men and women 50 or more years of age have a annual fecal occult blood test (FOBT) and a flexible sigmoidoscopy (FS) examination every five years to screen for colorectal cancer (CRC)...
  2. Effectiveness of Screening Colonoscopy in Reducing Deaths from Colorectal Cancer
    CHYKE ABADAMA DOUBENI; Fiscal Year: 2010
    ..did not reduce mortality from right-sided colon cancers, the part of the colon that is beyond the reach of sigmoidoscopy. However, those findings were controversial because that study was unable to distinguish screening from ..
  3. Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial
    Mona Fouad; Fiscal Year: 2013
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  4. Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial
    BARBARA O'BRIEN; Fiscal Year: 2013
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  5. A MicroRNA Approach to Screen for Sporadic Colon Cancer Exfoliately in Human Stoo
    Farid E Ahmed; Fiscal Year: 2010
    ..15). There are several other methods available for colon cancer screening [e.g., flexible sigmoidoscopy (16), CT colonography (virtual colonoscopy) (17), capsule endoscopy (18), double contrast barium enema (19), ..
  6. Interactive Multimedia Intervention to Improve Colonoscopy and Bowel Prep Adhere
    JOHN MATTHEW INADOMI; Fiscal Year: 2012
    ..Regardless of the primary strategy (fecal occult blood testing, sigmoidoscopy, colonoscopy, fecal DNA, computed tomographic colonography [virtual colonoscopy]) colonoscopy is required to ..
  7. PROSTATE, LUNG, COLORECTAL AND OVARIAN (PLCO) CANCER SCREENING TRIAL
    Claudine Isaacs; Fiscal Year: 2010
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  8. Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial
    BARBARA O apos BRIEN; Fiscal Year: 2010
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  9. Prostate, Lung, Colorectal and Ovarian (PLCO) Cancer Screening Trial - Lab
    Cheryl Robinson; Fiscal Year: 2009
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  10. PROSTATE, LUNG, COLORECTAL AND OVARIAN (PLCO) CANCER SCREENING TRIAL
    Claudine Isaacs; Fiscal Year: 2009
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  11. Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial
    BARBARA O apos BRIEN; Fiscal Year: 2009
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  12. Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial
    Saundra Buys; Fiscal Year: 2009
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  13. Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial
    Mona Fouad; Fiscal Year: 2010
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  14. Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial
    Mona Fouad; Fiscal Year: 2011
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  15. PROSTATE, LUNG, COLORECTAL AND OVARIAN (PLCO) CANCER SCREENING TRIAL
    KAREN STEINMETZ; Fiscal Year: 2011
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  16. Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial
    Mona Fouad; Fiscal Year: 2009
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  17. PROSTATE, LUNG, COLORECTAL AND OVARIAN (PLCO) CANCER SCREENING TRIAL
    Paul Kvale; Fiscal Year: 2010
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  18. Prostate, Lung, Colorectal and Ovarian (PLCO) Screening Trial
    BARBARA O'BRIEN; Fiscal Year: 2011
    ..PA) chest x-ray annually for four screens (except never smokers who received three annual screens), flexible sigmoidoscopy (FSG) at enrollment and again at the fourth or sixth annual screening interval depending on time of enrollment ..
  19. Colorectal Neoplasia in SELECT Participants
    M PETER LANCE; Fiscal Year: 2011
    ..the procedure and histopathology reports of SELECT participants who undergo lower gasatrointestinal endoscopy (sigmoidoscopy or colonoscopy) and removal of colorectal polyps as part of their usual clinical care while in the trial...
  20. MODELING SPATIAL ACCESSIBILITY TO LOWER ENDOSCOPY SERVICES IN THE UNITED STATES
    Min Lian; Fiscal Year: 2013
    ..Lower endoscopic examinations including flexible sigmoidoscopy and colonoscopy have been demonstrated to reduce the risks of incident CRC and CRC-specific mortality through ..
  21. Training African American Peers as Patient Navigators for Colon Cancer Screening
    Lina Jandorf; Fiscal Year: 2012
    ..More importantly, due to the preponderance of CRC in AAs beyond the reach of the flexible sigmoidoscopy, increased adherence to colonoscopy among AAs will save lives...
  22. Tailored Touchscreen Colorectal Cancer Prevention in Urban Core Clinics
    K Allen Greiner; Fiscal Year: 2010
    ..preference, be offered either an immunochemical fecal occult blood test (iFOBT-lnSure"), colonoscopy, or sigmoidoscopy. Participants will be randomized to either C (comparison group-computer delivered generic CRC information) or ..
  23. Improving Flexible Sigmoidoscopy in Women by Optical Analysis of Microvasculature
    HEMANT K contact ROY; Fiscal Year: 2010
    ..Flexible sigmoidoscopy (endoscopic evaluation of the distal colon) is performed in the community and has many advantages over other ..
  24. PEER OUTREACH TO FACILITATE COLORECTAL CANCER SCREENING IN SAFETY NET CLINICS
    Aimee S James; Fiscal Year: 2010
    ..The primary outcome of this study is completion of any acceptable CRC screen (FOBT, sigmoidoscopy, colonoscopy) at six-months after baseline, measured by chart review...
  25. CT Colonoscopy Screening for CRC:Comparative Effectiveness vs Traditional Models
    G Scott Gazelle; Fiscal Year: 2010
    ..reduce colorectal cancer incidence and mortality, and randomized controlled trials of screening with flexible sigmoidoscopy are currently in the field...
  26. PRE-VIEW An Interactive Video Doctor to Encourage Cancer Screening
    JUDITH MARY EILEEN WALSH; Fiscal Year: 2013
    ..cancer with Pap tests;or colorectal cancer with fecal occult blood tests, fecal immunochemical tests, sigmoidoscopy or colonoscopy when indicated and to engage in shared decision-making with primary care physicians about ..
  27. Preclinical assay development of a novel Colon Cancer Marker (CCSA-4)
    JACK CLEMENS; Fiscal Year: 2007
    ..Several methods are available for detection of colon cancer, including fecal occult blood testing, flexible sigmoidoscopy, double contrast barium enema and colonoscopy...
  28. HIV, Gut Mucosal Turnover and Inflammation, and the Risk of Colorectal Neoplasia
    Ma Somsouk; Fiscal Year: 2013
    ..NIH-sponsored HIV-infected cohort (SCOPE) of over 1,360 subjects where 186 subjects have already undergone sigmoidoscopy and biopsies...
  29. Computer Support for the Colon Cancer Screening in PLCO Cancer Screening Trials
    William Lake; Fiscal Year: 2009
    ..and annually for 5 years Digital rectal exam (men only), at initial visit and annually for 3 years Flexible sigmoidoscopy, at initial visit and after 5 years in study (colon cancer screening) Chest X-ray: smokers had test at entry ..
  30. Computer Support for Prostate Cancer Screening in the PLCO Cancer Screening Trial
    William Lake; Fiscal Year: 2010
    ..rectal exam (men only), at initial visit and annually for 3 years (screening for prostate cancer) Flexible sigmoidoscopy, at initial visit and after 5 years in study Chest X-ray: smokers had test at entry and annually for 3 years...
  31. Computer Support for Prostate Cancer Screening in the PLCO Cancer Screening Trial
    William Lake; Fiscal Year: 2012
    ..rectal exam (men only), at initial visit and annually for 3 years (screening for prostate cancer) Flexible sigmoidoscopy, at initial visit and after 5 years in study Chest X-ray: smokers had test at entry and annually for 3 years...
  32. Computer Support for Prostate Cancer Screening in the PLCO Cancer Screening Trial
    William Lake; Fiscal Year: 2011
    ..rectal exam (men only), at initial visit and annually for 3 years (screening for prostate cancer) Flexible sigmoidoscopy, at initial visit and after 5 years in study Chest X-ray: smokers had test at entry and annually for 3 years...
  33. Tailored Interactive Multimedia to Reduce Colorectal CA Screening Disparities
    ANTHONY FRANCIS JERANT; Fiscal Year: 2013
    ..Screening methods targeted will be fecal occult blood testing, flexible sigmoidoscopy, and colonoscopy...
  34. DNA METHYLATION AND COLORECTAL POLYPS
    Robert Haile; Fiscal Year: 2003
    ..We propose to accomplish our objective by adding a methylation component onto an existing sigmoidoscopy-based case-control study of environmental and genetic risk factors for adenomatous polyps of the large bowel ..
  35. Quantifying Risk to Target Screening Colonoscopy
    Thomas Imperiale; Fiscal Year: 2009
    ..polyps (collectively known as "advanced neoplasia") could allow use of different screening tests (CY, sigmoidoscopy, fecal occult blood) to be tailored to risk...
  36. Modeling Effective Health Policies for Colorectal Cancer
    ANN GRAHAM ZAUBER; Fiscal Year: 2013
    ..data on genomics, biomarkers, pathways, and the upcoming data from randomized controlled trials of flexible sigmoidoscopy screening...
  37. GENE-ENVIRONMENT EFFECTS AND COLON ADENOMAS
    Henry Lin; Fiscal Year: 2000
    ..The project will use subjects (1,000 cases and 1,000 controls) from an ongoing study titled, "A sigmoidoscopy-based case-control study of polyps...
  38. Telehealth Intervention for Colorectal Cancer Screening
    Susan Rawl; Fiscal Year: 2003
    ..Regular endoscopic screening with flexible sigmoidoscopy or colonoscopy leads to removal of precancerous polyps, which has been shown to decrease CRC incidence by 75% ..
  39. Role of Physicians and Their Groups in Cancer Screening
    George Wright; Fiscal Year: 2005
    ..claims files for the year 2002 will be analyzed to calculate rates for five screening tests (mammography, sigmoidoscopy, fecal occult blood, PAP smears, and PSA tests)...
  40. Association of PPAR gamma ligands & colonic neoplasia
    James Lewis; Fiscal Year: 2006
    ..be categorized according to the presence or absence of adenomatous neoplasia in the distal colon on the second sigmoidoscopy. Use of TZDs prior to the colonoscopy or second sigmoidoscopy will be compared among the groups...
  41. Colorectoral cancer screening decisions in primary care
    James Dolan; Fiscal Year: 2006
    ..screening guidelines for average risk patients endorse 5 options: annual fecal occult blood tests, flexible sigmoidoscopy every 5 years, combined annual fecal occult blood tests and flexible sigmoidoscopy every 5 years, double ..
  42. Increasing CRC Screening in Health Plan Members
    Karen Glanz; Fiscal Year: 2007
    ..that asymptomatic adults overage 50 periodically obtain screening by one of several modalities (FOBT, sigmoidoscopy,colonoscopy,or double contrast barium enema)...
  43. Adherence and the Economics of Colon Cancer Screening
    John Inadomi; Fiscal Year: 2009
    ..Strategies to be evaluated include fecal occult blood testing (FOBT), flexible sigmoidoscopy (FS), colonoscopy, and virtual colonoscopy (VC, when approved for CRC screening)...
  44. Structure M.tuberculosis Adenosine Kinase Design Antimicrobial Nucleoside Analogs
    Mark Dignan; Fiscal Year: 2009
    ..36% of respondents in Appalachian Kentucky reported screening for colorectal cancer (FOBT or flexible sigmoidoscopy or colonoscopy) in accordance with guidelines of the US Preventive Services Task Force compared to 43...
  45. ENHANCING DIAGNOSTIC EVALUATION IN COLORECTAL CANCER
    Ronald Myers; Fiscal Year: 1999
    ..Experts consider CDE as either colonoscopy or double air-contrast barium enema x-ray (BE) with flexible sigmoidoscopy. These procedures require primary care physician (PCP) referral(s) to gastroenterologists and colorectal ..
  46. PROSPECTIVE STUDY OF DIET AND COLORECTAL ADENOMAS
    Walter Willett; Fiscal Year: 1990
    ..The proposed study population will be restricted to subjects from both cohorts who have colonoscopy or sigmoidoscopy between 1986 and 1990, and will exclude persons who reported polyps before 1986...
  47. ADDING NEW FECAL OCCULT BLOOD TESTS TO SIGMOIDOSCOPY
    Theodore Levin; Fiscal Year: 2000
    ..reduces mortality, but it remains unclear whether the combination of a fecal occult blood test (FOBT) and sigmoidoscopy offers any advantage over either method used alone...
  48. RE-AIM Evaluation of Tailored Smoking Harm Reduction
    Russell Glasgow; Fiscal Year: 2007
    ..reaching and involving smokers about to have out-patient surgery or an invasive endoscopic medical procedure (sigmoidoscopy/colonoscopy) in Kaiser Permanente-Colorado, but who decline to participate in cessation-based smoking ..
  49. Predictors of Cancer Screening in Diverse Practices
    Richard Zimmerman; Fiscal Year: 2005
    ..6 percent reported fecal occult blood screening (FOBT) within the last year and 33.6 percent reported flexible sigmoidoscopy (FS) within the last five years...
  50. HEALTHTOUCH--COMPUTER-ASSISTED CANCER PREVENTION
    W MC CARTER; Fiscal Year: 1992
    ..of cancer prevention activities, including mammogram, BSE, physician breast examination, pap smears, flexible sigmoidoscopy, fecal occult blood tests, digital rectal exams, and oral examinations...
  51. Interval for colon cancer screening by sigmoidoscopy
    Noel Weiss; Fiscal Year: 2002
    Screening for colorectal cancer (CRC) by sigmoidoscopy results in the identification and removal of pre-cancerous lesions (adenomatous polyps), thus preventing incident cases of cancer...
  52. Repeat and Followup Tests (RAFTs) after Colonoscopy
    Robert Richards; Fiscal Year: 2006
    ..unreadable] Prior research by the candidate demonstrated that African Americans receive less colonoscopy and sigmoidoscopy than whites...
  53. INCREASING COLORECTAL CANCER SCREENING
    Jane Zapka; Fiscal Year: 2000
    ..However, rates of patient adherence with screening sigmoidoscopy recommendations are low and little research has been done to explain this limited compliance or to identify ..
  54. NEW STRATEGIES FOR COLORECTAL CANCER CONTROL
    Paul Schroy; Fiscal Year: 2000
    ..Provider attitudes and practice patterns will be monitored and compared using pre-post-educational surveys and sigmoidoscopy appointment schedules, respectively. Dr...
  55. CASE-CONTROL EVALUATIONS OF COLORECTAL CANCER SCREENING
    Joe Selby; Fiscal Year: 1990
    We propose to evaluate the efficacy of three screening tests - digital rectal examination, sigmoidoscopy, and fecal occult blood testing - in reducing mortality from colorectal cancer...
  56. PROSTATE, LUNG, COLORECTAL & OVARIAN CANCER
    Edward Gelmann; Fiscal Year: 2000
    ..In females and males (1) screening with flexible sigmoidoscopy (60 cm sigmoidoscope) can reduce mortality from colo-rectal cancer; and, (2) screening with chest x-ray can ..
  57. Molecular Biomarkers/Non-invasive Diagnosis Of Colon CA
    SMITI GUPTA; Fiscal Year: 2002
    ..However, FOBT screening suffers from large numbers of false positive and negative results. Whereas periodic sigmoidoscopy can significantly reduce mortality from colon cancer, currently only about 7 percent of eligible persons ..
  58. A New Marker for Colon Cancer Screening
    Robert Kinders; Fiscal Year: 2001
    ..suitable for use in a screening mode in which patients with a positive test result would be worked up by sigmoidoscopy or colonoscopy...
  59. GENES, ANTICARCINOGENS AND COLON NEOPLASMS
    Henry Lin; Fiscal Year: 2006
    ..Three case-control studies will be used to assess effects of genetic variation on colon neoplasms: a Kaiser sigmoidoscopy study of adenomas (1,700 subjects); a Univ...
  60. IMPROVING COLORECTAL CANCER SCREENING RATES
    Patricia Ganz; Fiscal Year: 2001
    ..will be to increase colorectal cancer screening rates with fecal occult blood testing (FOBT) and flexible sigmoidoscopy in men and women age greater than or equal to 50 years who are enrolled in the health plan...