Genomes and Genes
Summary: Endoscopic examination, therapy or surgery of the luminal surface of the colon.
Articles from Journal RESEARCH
Articles from Journal RESEARCH1
Publications368 found, 100 shown here
- Colonoscopic polypectomy and long-term prevention of colorectal-cancer deathsAnn G Zauber
Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
N Engl J Med 366:687-96. 2012..In the National Polyp Study (NPS), colorectal cancer was prevented by colonoscopic removal of adenomatous polyps. We evaluated the long-term effect of colonoscopic polypectomy in a study on mortality from colorectal cancer...
- Screening and surveillance for the early detection of colorectal cancer and adenomatous polyps, 2008: a joint guideline from the American Cancer Society, the US Multi-Society Task Force on Colorectal Cancer, and the American College of RadiologyBernard Levin
The University of Texas MD Anderson Cancer Center, Houston, TX, USA
CA Cancer J Clin 58:130-60. 2008..It is the strong opinion of these 3 organizations that colon cancer prevention should be the primary goal of screening...
- Polyp miss rate determined by tandem colonoscopy: a systematic reviewJeroen C van Rijn
Department of Clinical Epidemiology and Biostatistics, Academic Medical Center University of Amsterdam, Amsterdam, The Netherlands
Am J Gastroenterol 101:343-50. 2006b>Colonoscopy is the best available method to detect and remove colonic polyps and therefore serves as the gold standard for less invasive tests such as virtual colonoscopy...
- CT colonography versus colonoscopy for the detection of advanced neoplasiaDavid H Kim
Department of Radiology, University of Wisconsin Medical School, Madison 53792 3252, USA
N Engl J Med 357:1403-12. 2007Advanced neoplasia represents the primary target for colorectal-cancer screening and prevention. We compared the diagnostic yield from parallel computed tomographic colonography (CTC) and optical colonoscopy (OC) screening programs.
- Protection from colorectal cancer after colonoscopy: a population-based, case-control studyHermann Brenner
German Cancer Research Center, University Clinic Heidelberg, University of Heidelberg, Germany
Ann Intern Med 154:22-30. 2011b>Colonoscopy with detection and removal of adenomas is considered a powerful tool to reduce colorectal cancer (CRC) incidence...
- Accuracy of CT colonography for detection of large adenomas and cancersC Daniel Johnson
Mayo Clinic Arizona, Scottsdale, AZ, USA
N Engl J Med 359:1207-17. 2008..Computed tomographic (CT) colonography is a noninvasive option in screening for colorectal cancer. However, its accuracy as a screening tool in asymptomatic adults has not been well defined...
- American College of Gastroenterology guidelines for colorectal cancer screening 2009 [corrected]Douglas K Rex
Indiana University Medical Center, IU Hospital, Indianapolis 46202, USA
Am J Gastroenterol 104:739-50. 2009..The CRC screening tests are now grouped into cancer prevention tests and cancer detection tests. Colonoscopy every 10 years, beginning at age 50, remains the preferred CRC screening strategy...
- Protection from right- and left-sided colorectal neoplasms after colonoscopy: population-based studyHermann Brenner
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Bergheimer Str 20, D 69115 Heidelberg, Germany
J Natl Cancer Inst 102:89-95. 2010b>Colonoscopy is used for early detection and prevention of colorectal cancer, but evidence on the magnitude of overall protection and protection according to anatomical site through colonoscopy performed in the community setting is sparse...
- Asia Pacific consensus recommendations for colorectal cancer screeningJ J Y Sung
The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, NT, Hong Kong
Gut 57:1166-76. 2008..Faecal occult blood test (FOBT, guaiac-based and immunochemical tests), flexible sigmoidoscopy and colonoscopy are recommended for CRC screening. Double-contrast barium enema and CT colonography are not preferred...
- Quality indicators for colonoscopyDouglas K Rex
Am J Gastroenterol 101:873-85. 2006
- Fecal transplantation, through colonoscopy, is effective therapy for recurrent Clostridium difficile infectionEero Mattila
Department of Infectious Diseases, Helsinki University Central Hospital, Helsinki, Finland
Gastroenterology 142:490-6. 2012..Treatment of recurrent Clostridium difficile infection (CDI) with antibiotics leads to recurrences in up to 50% of patients. We investigated the efficacy of fecal transplantation in treatment of recurrent CDI...
- Factors determining the quality of screening colonoscopy: a prospective study on adenoma detection rates, from 12,134 examinations (Berlin colonoscopy project 3, BECOP-3)Andreas Adler
Central Interdisciplinary Endoscopy, Charité Medical University, Campus Virchow Hospital, Berlin, Germany
Gut 62:236-41. 2013Screening colonoscopy (SC) outcome quality is best determined by the adenoma detection rate (ADR). The substantial variability in the ADRs between endoscopists may reflect different skills, experience and/or equipment.
- Efficacy in standard clinical practice of colonoscopic polypectomy in reducing colorectal cancer incidenceF Citarda
Regina Elena Cancer Institute, Rome, Italy
Gut 48:812-5. 2001..aged 40-69 years, enrolled between 1980 and 1987 following a total colon examination (TCE) (that is, total colonoscopy or colonoscopy and double contrast barium enema), with removal of at least one adenoma larger than 5 mm in ..
- A randomized trial of aspirin to prevent colorectal adenomasJohn A Baron
Norris Cotton Cancer Center, Dartmouth Hitchcock Medical Center, Lebanon, NH, USA
N Engl J Med 348:891-9. 2003..Laboratory and epidemiologic data suggest that aspirin has an antineoplastic effect in the large bowel...
- High yields of small and flat adenomas with high-definition colonoscopes using either white light or narrow band imagingDouglas K Rex
Division of Gastroenterology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Gastroenterology 133:42-7. 2007Detection of adenomas is an important goal of colonoscopy. Narrow band imaging (NBI) might highlight adenomas and lead to higher rates of adenoma detection.
- Location of adenomas missed by optical colonoscopyPerry J Pickhardt
Department of Radiology, University of Wisconsin Medical School, E3 311 Clinical Science Center, 600 Highland Avenue, Madison, WI 53792 3252, USA
Ann Intern Med 141:352-9. 2004Previous estimates of the adenoma miss rate with optical colonoscopy (OC) are hindered by the use of OC as its own reference standard.
- Guidelines for colonoscopy surveillance after polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer and the American Cancer SocietySidney J Winawer
Memorial Sloan Kettering Cancer Center, New York, New York, USA
Gastroenterology 130:1872-85. 2006..In 2003 these guidelines were updated and colonoscopy was recommended as the only follow-up examination, stratification at baseline into low risk and higher risk for ..
- Association of colonoscopy and death from colorectal cancerNancy N Baxter
Li Ka Shing Knowledge Institute, St Michael s Hospital, University Health Network, University of Toronto, Toronto, Ontario, Canada
Ann Intern Med 150:1-8. 2009b>Colonoscopy is advocated for screening and prevention of colorectal cancer (CRC), but randomized trials supporting the benefit of this practice are not available.
- Analysis of administrative data finds endoscopist quality measures associated with postcolonoscopy colorectal cancerNancy N Baxter
Department of Surgery and Keenan Research Centre, Li Ka Shing Knowledge Institute, St Michael s Hospital, University of Toronto, Toronto, Ontario, Canada
Gastroenterology 140:65-72. 2011Most quality indicators for colonoscopy measure processes; little is known about their relationship to patient outcomes...
- Colonoscopic withdrawal times and adenoma detection during screening colonoscopyRobert L Barclay
Rockford Gastroenterology Associates, IL 61107, USA
N Engl J Med 355:2533-41. 2006b>Colonoscopy is commonly used to screen for neoplasia...
- Miss rate for colorectal neoplastic polyps: a prospective multicenter study of back-to-back video colonoscopiesD Heresbach
Department of Gastroenterology, Hospital Pontchaillou, Rennes, France
Endoscopy 40:284-90. 2008Polyp miss rates during colonoscopy have been calculated in a few tandem or back-to-back colonoscopy studies. Our objective was to assess the adenoma miss rate while limiting technique or operator expertise biases, i. e...
- Guidelines for colorectal cancer screening and surveillance in moderate and high risk groups (update from 2002)Stuart R Cairns
Digestive Diseases Centre, Brighton and Sussex University Hospitals, Royal Sussex County Hospital, Eastern Road, Brighton, UK
Gut 59:666-89. 2010..In other areas guidance is relatively unchanged, but the recent literature was reviewed and is included where appropriate...
- Efficacy of a nationwide screening colonoscopy program for colorectal cancerChristian P Pox
Department of Medicine, Ruhr Universitat Bochum, Knappschaftskrankenhaus, Bochum, Germany
Gastroenterology 142:1460-7.e2. 2012Screening colonoscopy examinations for colorectal cancer are offered in the United States and some European countries. Data on results and adverse effects of screening colonoscopy are limited...
- Screening colonoscopy for colorectal cancer in asymptomatic people: a meta-analysisYaron Niv
Department of Gastroenterology, Rabin Medical Center, Beilinson Hospital, Petach Tikva, 49100, Israel
Dig Dis Sci 53:3049-54. 2008The preferred method for screening asymptomatic people for colorectal cancer (CRC) is colonoscopy, according to the new American guidelines...
- Prevalence and variable detection of proximal colon serrated polyps during screening colonoscopyCharles J Kahi
Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA
Clin Gastroenterol Hepatol 9:42-6. 2011b>Colonoscopy may have a greater protective effect for distal colorectal cancer (CRC) than proximal CRC. Serrated polyps are frequently located in the proximal colon, can be missed during colonoscopy, and may progress to CRC...
- Results from the first three rounds of the Scottish demonstration pilot of FOBT screening for colorectal cancerR J C Steele
Department of Surgery, University of Dundee, Dundee, UK
Gut 58:530-5. 2009..To assess the effects of the first three rounds of a pilot colorectal screening programme based on guaiac faecal occult blood testing (gFOBT) and their implications for a national population-based programme...
- Appearance of enhanced tissue features in narrow-band endoscopic imagingKazuhiro Gono
Olympus Co, Ishikawa cho, Hachioji shi, Tokyo 192 8507, Japan
J Biomed Opt 9:568-77. 2004..The results of clinical tests in colonoscopy and esophagoscopy indicated that NBI will be useful as a supporting method for observation of the endoscopic ..
- Diagnosis and management of dysplasia in patients with inflammatory bowel diseasesSteven H Itzkowitz
The Dr Henry D Janowitz Division of Gastroenterology, Department of Medicine, The Mount Sinai School of Medicine, New York, New York 10029, USA
Gastroenterology 126:1634-48. 2004..The main objective of regular colonoscopy is to detect neoplasia at a surgically curative and preferably preinvasive stage, i.e., dysplasia...
- Activation of the mucosal immune system in irritable bowel syndromeVinton S Chadwick
Wakefield Gastroenterology Centre and Research Institute, Wakefield Hospital, Wellington, New Zealand
Gastroenterology 122:1778-83. 2002..A role for the mucosal immune system in the pathogenesis of irritable bowel syndrome is suggested by its association with intestinal infections...
- Screening for colorectal cancer: random comparison of guaiac and immunochemical faecal occult blood testing at different cut-off levelsL Hol
Department of Gastroenterology and Hepatology, Erasmus MC, University Medical Centre, Rotterdam, The Netherlands
Br J Cancer 100:1103-10. 2009..testing (FIT) provides quantitative test results, which allows optimisation of the cut-off value for follow-up colonoscopy. We conducted a randomised population-based trial to determine test characteristics of FIT (OC-Sensor micro, ..
- Maximizing detection of adenomas and cancers during colonoscopyDouglas K Rex
Indiana University Medical Center, Indianapolis, Indiana 46202, USA
Am J Gastroenterol 101:2866-77. 2006Some patients who undergo colonoscopy that appeared to have cleared the colorectum of neoplasia return within a short interval (1-3 yr) with colorectal cancer...
- Colonoscopy quality measures: experience from the NHS Bowel Cancer Screening ProgrammeThomas J W Lee
University Hospital of North Tees, Stockton on Tees, UK
Gut 61:1050-7. 2012b>Colonoscopy is central to colorectal cancer (CRC) screening. Success of CRC screening is dependent on colonoscopy quality...
- Participation and yield of colonoscopy versus non-cathartic CT colonography in population-based screening for colorectal cancer: a randomised controlled trialEsther M Stoop
Department of Gastroenterology and Hepatology, Erasmus University Medical Centre, Rotterdam, Netherlands
Lancet Oncol 13:55-64. 2012Screening for colorectal cancer is widely recommended, but the preferred strategy remains unidentified. We aimed to compare participation and diagnostic yield between screening with colonoscopy and with non-cathartic CT colonography.
- Colonoscopy and fecal occult blood test use in Germany: results from a large insurance-based cohortC Stock
Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany
Endoscopy 43:771-81. 2011b>Colonoscopy and guaiac-based fecal occult blood tests (FOBT) are recommended and offered for colorectal cancer (CRC) screening in Germany. We aimed to explore their utilization in a large insurance-based cohort.
- Effect of rising chemotherapy costs on the cost savings of colorectal cancer screeningIris Lansdorp-Vogelaar
Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
J Natl Cancer Inst 101:1412-22. 2009..We examined whether colorectal cancer screening would become cost saving with the widespread use of the newer, more expensive chemotherapies...
- Prevalence of missed adenomas in patients with inadequate bowel preparation on screening colonoscopyReena V Chokshi
Division of Gastroenterology, Washington University School of Medicine, St Louis, Missouri, USA
Gastrointest Endosc 75:1197-203. 2012The prevalence of missed polyps in patients with inadequate bowel preparation on screening colonoscopy is unknown.
- Acceptability and side-effects of colonoscopy and sigmoidoscopy in a screening settingCarlo Senore
Centro Prevenzione Oncologica Regione Piemonte and Azienda Ospedaliero Universitaria S Giovanni Battista di Torino, V San Francesco da Paola 31, 10123 Torino, Italy
J Med Screen 18:128-34. 2011..Quantitative information on adverse reactions associated with colorectal cancer (CRC) screening tests is useful to estimate the balance between benefit and risk in different strategies...
- High definition colonoscopy combined with i-Scan is superior in the detection of colorectal neoplasias compared with standard video colonoscopy: a prospective randomized controlled trialA Hoffman
I Med Clinic, Johannes Gutenberg University of Mainz, Langenbeckstrasse 1, Mainz, Germany
Endoscopy 42:827-33. 2010b>Colonoscopy is the accepted gold standard for the detection of colorectal cancer. The aim of the current study was to prospectively compare high definition plus (HD+) colonoscopy with I-Scan functionality (electronic staining) vs...
- Colonoscopic screening of average-risk women for colorectal neoplasiaPhilip Schoenfeld
Division of Gastroenterology, University of Michigan School of Medicine and Veterans Affairs Center for Excellence in Health Services Research, Ann Arbor 48105, USA
N Engl J Med 352:2061-8. 2005..villous adenomas, adenomas with high-grade dysplasia, or cancer) in men would be missed with the use of flexible sigmoidoscopy but detected by colonoscopy. In a tandem study, we examined the yield of screening colonoscopy in women.
- Randomized, controlled trial of standard-definition white-light, high-definition white-light, and narrow-band imaging colonoscopy for the detection of colon polyps and prediction of polyp histologyAmit Rastogi
University of Kansas School of Medicine, Veterans Affairs Medical Center, Kansas City, Missouri 64128 2295, USA
Gastrointest Endosc 74:593-602. 2011Missing adenomas and the inability to accurately differentiate between polyp histology remain the main limitations of standard-definition white-light (SD-WL) colonoscopy.
- Association between colonoscopy rates and colorectal cancer mortalityLinda Rabeneck
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Am J Gastroenterol 105:1627-32. 2010Although colonoscopy use has increased in the United States and Canada since the early 1990s, it is unclear whether this has been associated with benefit at the population level...
- The impact of suboptimal bowel preparation on adenoma miss rates and the factors associated with early repeat colonoscopyBenjamin Lebwohl
Department of Medicine, Division of Digestive and Liver Diseases, College of Physicians and Surgeons, Columbia University, New York, New York, USA
Gastrointest Endosc 73:1207-14. 2011There are no guidelines for the recommended interval to the next examination after colonoscopy with suboptimal bowel preparation.
- Utilization and yield of surveillance colonoscopy in the continued follow-up study of the polyp prevention trialAdeyinka O Laiyemo
Cancer Prevention Fellowship Program, Office of Preventive Oncology, National Cancer Institute, Bethesda, Maryland 20892, USA
Clin Gastroenterol Hepatol 7:562-7; quiz 497. 2009Prospective information on the use and yield of surveillance colonoscopy is limited...
- High accuracy of narrow band imaging without magnification for the real-time characterization of polyp histology and its comparison with high-definition white light colonoscopy: a prospective studyAmit Rastogi
Division of Gastroenterology and Hepatology, University of Kansas School of Medicine, Veterans Affairs Medical Center, Kansas City, Missouri 64128, USA
Am J Gastroenterol 104:2422-30. 2009Standard white light colonoscopy has limited ability to differentiate between polyp types (adenomatous vs. hyperplastic)...
- Sex-specific prevalence of adenomas, advanced adenomas, and colorectal cancer in individuals undergoing screening colonoscopyMonika Ferlitsch
Quality Assurance Working Group, Austrian Society for Gastroenterology and Hepatology, Vienna, Austria
JAMA 306:1352-8. 2011Although some studies have shown that men are at greater age-specific risk for advanced colorectal neoplasia than women, the age for referring patients to screening colonoscopy is independent of sex and usually recommended to be 50 years.
- Effect of repeated invitations on uptake of colorectal cancer screening using faecal occult blood testing: analysis of prevalence and incidence screeningR J C Steele
Department of Surgery, University of Dundee, UK
BMJ 341:c5531. 2010..To analyse the effects of prevalence and incidence screening on uptake and detection of cancer in an ongoing, dynamic programme for colorectal screening using faecal occult blood testing...
- High-definition chromocolonoscopy vs. high-definition white light colonoscopy for average-risk colorectal cancer screeningCharles J Kahi
Division of Gastroenterology and Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Am J Gastroenterol 105:1301-7. 2010..High-definition chromoscopy is used to increase the yield of colonoscopy for flat and depressed neoplasms; however, its role in average-risk patients undergoing routine screening ..
- Rates of new or missed colorectal cancers after colonoscopy and their risk factors: a population-based analysisBrian Bressler
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Gastroenterology 132:96-102. 2007The rate of new or missed colorectal cancer (CRC) after colonoscopy and their risk factors in usual practice are unknown. Our objective was to evaluate the rate and risk factors in a population-based study.
- Risk of developing colorectal cancer following a negative colonoscopy examination: evidence for a 10-year interval between colonoscopiesHarminder Singh
Department of Internal Medicine, Cancer Care Manitoba, University of Manitoba, Winnipeg
JAMA 295:2366-73. 2006Limited evidence exists to guide the optimal frequency of repeat endoscopic examination for colorectal cancer screening after a negative colonoscopy.
- Surveillance guidelines after removal of colorectal adenomatous polypsW S Atkin
Cancer Research UK, Colorectal Cancer Unit, St Mark s Hospital, Harrow, Middlesex HA1 3UJ, UK
Gut 51:V6-9. 2002
- Quality indicators for colonoscopy and the risk of interval cancerMichal F Kaminski
Department of Gastroenterology, Maria Sklodowska Curie Memorial Cancer Center and Institute of Oncology, Warsaw, Poland
N Engl J Med 362:1795-803. 2010..of detection of adenomatous lesions (tumors or polyps) and cecal intubation are recommended for use as quality indicators for screening colonoscopy, these measurements have not been validated, and their importance remains uncertain.
- A comparison of the immunochemical fecal occult blood test and total colonoscopy in the asymptomatic populationTamiya Morikawa
Department of Medicine and Medical Science, Okayama University Graduate School of Medicine and Dentistry, Japan
Gastroenterology 129:422-8. 2005..The aim of this study was to analyze the sensitivity of immunochemical FOBT and to compare the results with the findings from complete colonoscopy.
- Colorectal cancer: CT colonography and colonoscopy for detection--systematic review and meta-analysisPerry J Pickhardt
Department of Radiology, University of Wisconsin School of Medicine and Public Health, E3 311 Clinical Science Center, 600 Highland Ave, Madison, WI 53792 3252, USA
Radiology 259:393-405. 2011To perform a systematic review and meta-analysis of published studies assessing the sensitivity of both computed tomographic (CT) colonography and optical colonoscopy (OC) for colorectal cancer detection.
- Impact of colonic cleansing on quality and diagnostic yield of colonoscopy: the European Panel of Appropriateness of Gastrointestinal Endoscopy European multicenter studyFlorian Froehlich
Department of Gastroenterology PMU CHUV, Institute of Social and Preventive Medicine, University of Lausanne, Rue du Bugnon 44, CH 1011 Lausanne, Switzerland
Gastrointest Endosc 61:378-84. 2005The quality of colon cleansing is a major determinant of quality of colonoscopy. To our knowledge, the impact of bowel preparation on the quality of colonoscopy has not been assessed prospectively in a large multicenter study...
- Long term outcome of patients with active Crohn's disease exhibiting extensive and deep ulcerations at colonoscopyMatthieu Allez
Service de Gastroenterologie, Hopital Saint Louis, Paris, France
Am J Gastroenterol 97:947-53. 2002..Prediction of the clinical course of Crohn's disease (CD) is difficult in the long term. Our aim was to determine whether the presence of severe endoscopic lesions (SELs) may predict a higher risk of colectomy and penetrating complications...
- Detecting diminutive colorectal lesions at colonoscopy: a randomised controlled trial of pan-colonic versus targeted chromoscopyD P Hurlstone
Gastroenterology and Liver Unit, Royal Hallamshire Hospital, Sheffield, UK
Gut 53:376-80. 2004..Previous data have suggested that pan-chromoscopy may improve detection rates. No randomised control trial has been performed examining detection rates of such lesions while controlling for extubation time and lavage effect...
- ASGE guideline: colorectal cancer screening and surveillanceRaquel E Davila
American Society for Gastrointestinal Endoscopy, 1520 Kensington Road, Ste 202, Oak Brook, IL 60523, USA
Gastrointest Endosc 63:546-57. 2006
- Colorectal cancer in patients under close colonoscopic surveillanceDouglas J Robertson
Section of Gastroenterology, VA Medical Center, White River Junction, Vermont 05009, USA
Gastroenterology 129:34-41. 2005..We determined the incidence of CRC in patients under colonoscopic surveillance and examined the circumstances and risk factors for CRC and adenoma with high-grade dysplasia...
- Barriers to colorectal cancer screening among Medicare consumersCarrie N Klabunde
Health Services and Economics Branch, Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland, USA
Am J Prev Med 30:313-9. 2006..Few studies have examined lack of physician recommendation and other reasons for under-utilization of colorectal cancer (CRC) screening in the Medicare population...
- The impact of colon cleanliness assessment on endoscopists' recommendations for follow-up colonoscopyShomron Ben-Horin
Department of Gastroenterology, Sheba Medical Center, and Sackler School of Medicine, Tel Aviv University, Tel Hashomer, Israel
Am J Gastroenterol 102:2680-5. 2007Repeat colonoscopy is advocated for low-quality preparations. However, there are few data on how endoscopists assess the quality of bowel preparation...
- The advanced adenoma as the primary target of screeningSidney J Winawer
Department of Medicine, Memorial Sloan Kettering Cancer Center, and Weill Medical College of Cornell University, New York, New York 10021, USA
Gastrointest Endosc Clin N Am 12:1-9, v. 2002....
- Trends in colorectal cancer test use among vulnerable populations in the United StatesCarrie N Klabunde
Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, MD 20892 7344, USA
Cancer Epidemiol Biomarkers Prev 20:1611-21. 2011..This study examines recent national trends in CRC test use, including among vulnerable populations...
- Quality in the technical performance of colonoscopy and the continuous quality improvement process for colonoscopy: recommendations of the U.S. Multi-Society Task Force on Colorectal CancerDouglas K Rex
Department of Medicine Gastroenterology, Indiana University Medical Center, Indianapolis, USA
Am J Gastroenterol 97:1296-308. 2002
- Colonoscopy versus fecal immunochemical testing in colorectal-cancer screeningEnrique Quintero
Department of Gastroenterology, Hospital Universitario de Canarias, Tenerife, Spain
N Engl J Med 366:697-706. 2012b>Colonoscopy and fecal immunochemical testing (FIT) are accepted strategies for colorectal-cancer screening in the average-risk population.
- Colorectal cancer screening: scientific reviewJudith M E Walsh
Division of General Internal Medicine, Department of Medicine, Women s Health Clinical Research Center, University of California San Francisco, Campus Box 1793, 1635 Divisadero Suite 600, San Francisco, CA 94115, USA
JAMA 289:1288-96. 2003..Clinicians are challenged to ensure that eligible patients undergo colorectal cancer screening and to guide patients in choosing what tests to receive...
- Proximal and large hyperplastic and nondysplastic serrated polyps detected by colonoscopy are associated with neoplasiaMitchal A Schreiner
Portland VA Medical Center and Oregon Health and Science University, Portland, Oregon, USA
Gastroenterology 139:1497-502. 2010..We investigated whether detection of proximal nondysplastic serrated polyps (ND-SP) at screening and surveillance colonoscopies is associated with advanced neoplasia...
- Quality indicators for colonoscopyDouglas K Rex
ASGE Communications Department, 1520 Kensington Road, Suite 202, Oak Brook, IL 60523, USA
Gastrointest Endosc 63:S16-28. 2006
- Computed virtual chromoendoscopy versus standard colonoscopy with targeted indigocarmine chromoscopy: a randomised multicentre trialJ Pohl
Department of Internal Medicine II, Dr Horst Schmidt Klinik, Weisbaden, Germany
Gut 58:73-8. 2009b>Colonoscopy is the accepted gold standard for screening of neoplastic colorectal lesions, but the substantial miss rate remains a challenge...
- Higher adenoma detection rates with cap-assisted colonoscopy: a randomised controlled trialAmit Rastogi
Gastroenterology and Hepatology, Veterans Affairs Medical Center, Kansas City, Missouri 64128 2295, USA
Gut 61:402-8. 2012Cap-assisted colonoscopy (CAC) uses a small plastic transparent cap attached to the tip of the colonoscope that can depress and flatten colonic folds and thus improve visualisation of their proximal aspects...
- The use of screening colonoscopy for patients cared for by the Department of Veterans AffairsHashem B El-Serag
Houston Center for Quality of Care and Utilization Studies, Michael E DeBakey VA Medical Center, Baylor College of Medicine, Houston, TX 77030, USA
Arch Intern Med 166:2202-8. 2006Medicare data indicate an increase in colorectal cancer (CRC) screening using colonoscopy and a decline in fecal occult blood testing, flexible sigmoidoscopy, and double-contrast barium enema...
- Physician and patient factors associated with ordering a colon evaluation after a positive fecal occult blood testBarbara Turner
Division of General Internal Medicine BT, University of Pennsylvania, Philadelphia, PA, USA
J Gen Intern Med 18:357-63. 2003Successful colorectal cancer screening relies in part on physicians ordering a complete diagnostic evaluation of the colon (CDE) with colonoscopy or barium enema plus sigmoidoscopy after a positive screening fecal occult blood test (FOBT).
- Narrow-band imaging without high magnification to differentiate polyps during real-time colonoscopy: improvement with experienceJason N Rogart
Section of Digestive Diseases, Yale University School of Medicine, New Haven, Connecticut 06520 8019, USA
Gastrointest Endosc 68:1136-45. 2008There is no widely adopted, easily applied method for distinguishing between adenomatous and nonadenomatous polyps during real-time colonoscopy.
- High colonoscopic prevalence of proximal colon serrated polyps in average-risk men and womenCharles J Kahi
Department of Medicine, Division of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
Gastrointest Endosc 75:515-20. 2012Proximal colon serrated polyps likely contribute to the decreased protection of colonoscopy against right-sided colorectal cancer.
- Screening colonoscopy and risk for incident late-stage colorectal cancer diagnosis in average-risk adults: a nested case-control studyChyke A Doubeni
Department of Family Medicine and Community Health, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce Street, Gates 2, Philadelphia, PA 19104, USA
Ann Intern Med 158:312-20. 2013The effectiveness of screening colonoscopy in average-risk adults is uncertain, particularly for right colon cancer.
- Value of magnifying endoscopy in classifying colorectal polyps based on vascular patternJ J W Tischendorf
Department of Gastroenterology, Hepatology and Metabolic Diseases, University Hospital Aachen, D 52074 Aachen, Germany
Endoscopy 42:22-7. 2010..The aim of this study was to evaluate the diagnostic accuracy of NBI endoscopy with and without high magnification for the differentiation of neoplastic from non-neoplastic colorectal polyps...
- Terminal ileal photography or biopsy to verify total colonoscopy: does the endoscope agree with the microscope?Nick Powell
Department of Gastroenterology, Queen Elizabeth Hospital, Woolwich, London, UK
Gastrointest Endosc 66:320-5. 2007Various modalities exist to document the extent of colonoscopy, including a terminal ileum (TI) biopsy, which is considered the criterion standard by some authorities...
- Diagnosis of depth of invasion for early colorectal cancer using magnifying colonoscopyHisatomo Ikehara
Endoscopy Division, National Cancer Center Hospital, Tokyo, Japan
J Gastroenterol Hepatol 25:905-12. 2010..m.-d.) invasion should not be treated with endoscopic mucosal resection due to the higher incidence of lymph-node metastasis. It is, therefore, clinically important to accurately diagnose s.m.-d. lesions before treatment...
- Narrow-band imaging magnification predicts the histology and invasion depth of colorectal tumorsHiroyuki Kanao
Department of Medicine and Molecular Science, Hiroshima University, Hiroshima, Japan
Gastrointest Endosc 69:631-6. 2009..There are several reports concerning the differential diagnosis of non-neoplastic and neoplastic colorectal lesions by narrow-band imaging (NBI). However, there are only a few NBI articles that assessed invasion depth...
- Prevalence of advanced histological features in diminutive and small colon polypsNeil Gupta
Division of Gastroenterology, Kansas City Veterans Affairs Medical Center, Kansas City, Missouri, USA
Gastrointest Endosc 75:1022-30. 2012..resect, and discard" strategies for diminutive (≤ 5 mm) or small (6-9 mm) polyps to reduce screening colonoscopy costs...
- Cap-fitted colonoscopy: a randomized, tandem colonoscopy study of adenoma miss ratesDavid G Hewett
Division of Gastroenterology Hepatology, Department of Medicine, Indiana University School of Medicine, Indianapolis, Indiana, USA
Gastrointest Endosc 72:775-81. 2010Failures of adenoma detection diminish the effectiveness of colonoscopy.
- Colorectal endoscopy, advanced adenomas, and sessile serrated polyps: implications for proximal colon cancerAndrea N Burnett-Hartman
Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
Am J Gastroenterol 107:1213-9. 2012b>Colonoscopy is associated with a decreased risk of colorectal cancer but may be more effective in reducing the risk of distal than proximal malignancies...
- Cost-effectiveness of mass screening for colorectal cancer: choice of fecal occult blood test and screening strategyIradj Sobhani
Gastroenterology Unit, Albert Chenevier Henri Mondor Hospital, Assistance Publique Hopitaux de Paris, Paris, France
Dis Colon Rectum 54:876-86. 2011..A positive test selects those who should undergo colonoscopy to ensure early detection of colorectal cancer. Guaiac fecal occult blood test has low sensitivity...
- Cost-effectiveness analysis of a quantitative immunochemical test for colorectal cancer screeningJanneke A Wilschut
Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, Rotterdam, The Netherlands
Gastroenterology 141:1648-55.e1. 2011..We aimed to identify the most cost-effective FIT cutoff level for referral to colonoscopy based on data from these trials and allowing for differences in screening ages.
- Patients' experiences and reported barriers to colonoscopy in the screening context--a systematic review of the literatureSue Anne McLachlan
Oncology Department, St Vincent s Hospital, Melbourne, Australia
Patient Educ Couns 86:137-46. 2012A systematic review of the literature was conducted to characterise patients' own experience of colonoscopy in the screening context.
- Accuracy of in vivo optical diagnosis of colon polyp histology by narrow-band imaging in predicting colonoscopy surveillance intervalsNeil Gupta
Division of Gastroenterology, Kansas City Veterans Affairs Medical Center, Kansas City, Missouri 64128, USA
Gastrointest Endosc 75:494-502. 2012..Narrow-band imaging (NBI) has been shown to predict polyp histology with moderate to high accuracy in several studies...
- Risk stratification for colon neoplasia: screening strategies using colonoscopy and computerized tomographic colonographyOtto S Lin
Gastroenterology Section, Virginia Mason Medical Center, 1100 Ninth Avenue, Seattle, WA 98101, USA
Gastroenterology 131:1011-9. 2006We developed a risk index to identify low-risk patients who may be screened for colorectal cancer with computerized tomographic colonography (CTC) instead of colonoscopy.
- Diagnostic value of CT-colonography as compared to colonoscopy in an asymptomatic screening population: a meta-analysisMargriet C de Haan
Department of Radiology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
Eur Radiol 21:1747-63. 2011..Previous meta-analyses on CT-colonography included both average and high risk individuals, which may overestimate the diagnostic value in screening. A meta-analysis was performed to obtain the value of CT-colonography for screening...
- Accuracy for optical diagnosis of small colorectal polyps in nonacademic settingsTeaco Kuiper
Department of Gastroenterology and Hepatology, Academic Medical Centre, Amsterdam, The Netherlands
Clin Gastroenterol Hepatol 10:1016-20; quiz e79. 2012..We performed a prospective study to assess the accuracy of optical diagnosis of small colorectal polyps in a nonacademic setting (the DISCOUNT trial) by using high-resolution endoscopy (HRE) and narrow-band imaging (NBI)...
- The Asia-Pacific Colorectal Screening score: a validated tool that stratifies risk for colorectal advanced neoplasia in asymptomatic Asian subjectsKhay Guan Yeoh
Department of Medicine, National University of Singapore
Gut 60:1236-41. 2011..To develop and validate a clinical risk score predictive of risk for colorectal advanced neoplasia for Asia...
- Validity of self-reported colorectal cancer screening behaviorM Baier
American Medical Center Cancer Research Center, Lakewood, Colorado 80214, USA
Cancer Epidemiol Biomarkers Prev 9:229-32. 2000..Cases who had received a fecal occult blood test (FOBT), flexible sigmoidoscopy, and/or colonoscopy, and controls who had no record of colorectal screening were identified among 40-75-year-old members of the ..
- Development and validation of a training module on the use of narrow-band imaging in differentiation of small adenomas from hyperplastic colorectal polypsAna Ignjatovic
Wolfson Unit for Endoscopy, St Mark s Hospital, Harrow, Middlesex, United Kingdom
Gastrointest Endosc 73:128-33. 2011Experts are accurate in differentiating small adenomas from hyperplastic polyps at colonoscopy by using narrow-band imaging (NBI).
- Ascertainment of colonoscopy indication using administrative dataDeborah A Fisher
Center for Health Services Research in Primary Care, Durham Veterans Affairs Medical Center, Durham, NC, USA
Dig Dis Sci 55:1721-5. 2010Administrative procedure code data can estimate colonoscopy utilization; however, determining colonoscopy indication is more difficult as procedure codes do not inherently reflect the purpose (screening, surveillance, diagnosis) of the ..
- Double-balloon endoscopy versus magnet-imaging enhanced colonoscopy for difficult colonoscopies, a randomized studyT Suzuki
Division of Gastroenterology and Hepatology, Department of Internal Medicine, Tokai University School of Medicine, Isehara, Kanagawa, Japan
Endoscopy 44:38-42. 2012Studies have estimated that failure of cecal intubation occurs with conventional colonoscopy in up to 10 % of cases...
- Diagnostic accuracy of narrow-band imaging for the differentiation of neoplastic from non-neoplastic colorectal polyps: a meta-analysisL Wu
Department of Colorectal and Anal Surgery, First Affiliated Hospital, Guangxi Medical University, Nanning, Guangxi, China
Colorectal Dis 15:3-11. 2013..However, the real accuracy for the differentiation of neoplastic from non-neoplastic polyps by NBI for the colorectum is still unknown...
- Utilization of surveillance colonoscopy in community practiceRobert E Schoen
Department of Medicine, University of Pittsburgh Medical Center, and University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania 15213 2582, USA
Gastroenterology 138:73-81. 2010The recommended timing of surveillance colonoscopy for individuals with adenomatous polyps is based on adenoma histology, size, and number. The burden and cost of surveillance colonoscopy are significant...
- Low adherence to colonoscopy in the screening of first-degree relatives of patients with colorectal cancerLuis Bujanda
Department of Gastroenterology, Donostia Hospital, San Sebastian, Spain
Gut 56:1714-8. 2007b>Colonoscopy is one of the methods of choice for screening relatives of patients with colorectal cancer.
- Memories of colonoscopy: a randomized trialDonald A Redelmeier
Department of Medicine, University of Toronto, Toronto, Ontario, Canada
Pain 104:187-94. 2003..We studied consecutive outpatients undergoing colonoscopy who were medically stable, mentally competent, and able to speak English (n=682)...
- Computer-aided classification of colorectal polyps based on vascular patterns: a pilot studyJ J W Tischendorf
Medical Department III Gastroenterology, Hepatology and Metabolic Diseases, Aachen University Hospital, RWTH Aachen University, 52074 Aachen, Germany
Endoscopy 42:203-7. 2010..The aim of the present study was to develop and evaluate a computer-based method for automated classification of colorectal polyps on the basis of vascularization features...
- Prevalence of nonpolypoid (flat and depressed) colorectal neoplasms in asymptomatic and symptomatic adultsRoy M Soetikno
Gastroenterology Section, Veterans Affairs Palo Alto Health Care System, Palo Alto, California 94304, USA
JAMA 299:1027-35. 2008..Prevention has focused on the detection and removal of polypoid neoplasms. Data are limited on the significance of nonpolypoid colorectal neoplasms (NP-CRNs)...
- Pancolonic chromoendoscopy with indigo carmine versus standard colonoscopy for detection of neoplastic lesions: a randomised two-centre trialJürgen Pohl
Department of Internal Medicine II, Dr Horst Schmidt Klinik, Wiesbaden, Germany
Gut 60:485-90. 2011b>Colonoscopy is the accepted gold standard for detecting colorectal adenomas, but the miss rate, especially for small and flat lesions, remains unacceptably high...
- Endoscopic band ligation with a water-jet scope for the treatment of colonic diverticular hemorrhageNaoki Ishii
Department of Gastroenterology, St Luke s International Hospital, Kyoto, Japan
Dig Endosc 22:232-5. 2010..EBL with a water-jet scope is considered to be a safe and effective endoscopic treatment for colonic diverticular hemorrhage...
- Understanding/ Treating Neuropsychiatric Symptoms of Pediatric Physical IllnessEva Szigethy; Fiscal Year: 2009..abstract_text> ..
- A MicroRNA Approach to Screen for Sporadic Colon Cancer Exfoliately in Human StooFarid E Ahmed; Fiscal Year: 2010..shows higher sensitivity than FOBT, and results in better compliance &is more economical than invasive colonoscopy. We studied the expression of 15 mature miRNAs by stem-loop RT primers and TaqMan minor grove binding probes in ..
- Real-Time Optical Diagnosis of Inflammatory Bowel Disease using SFDISylvain Gioux; Fiscal Year: 2013..real-time quantification of tissue optical properties, inclding perfusion, hydration, and metabolism during colonoscopy, thus improving IBD detection...
- Interactive Multimedia Intervention to Improve Colonoscopy and Bowel Prep AdhereJOHN MATTHEW INADOMI; Fiscal Year: 2012..Regardless of the primary strategy (fecal occult blood testing, sigmoidoscopy, colonoscopy, fecal DNA, computed tomographic colonography [virtual colonoscopy]) colonoscopy is required to evaluate ..
- Lipid genotypes, phenotypes, and colorectal adenomas: Elucidating mechanismsPolly A Newcomb; Fiscal Year: 2013..We will utilize extant biospecimens and questionnaire data from a completed colonoscopy study among enrollees of Group Health (GH), a large healthcare provider in Washington State...
- Faith-Based Approaches to Treating Hypertension and Colon Cancer PreventionHayley S Thompson; Fiscal Year: 2013..have been successfully tested in increasing CRC screening rates, few have focused on improving use of screening colonoscopy among black men in a non- practice community-based setting...
- Characterization of the Plasma Proteome in Mouse Models of Colon CancerKenneth E Hung; Fiscal Year: 2010..Early diagnosis of colorectal cancer by colonoscopy increases the probability of survival...
- DEVELOPING VIRTUAL COLONOSCOPY FOR CANCER SCREENINGJEROME Z LIANG; Fiscal Year: 2013..Computed tomography colonography (CTC) or CT-based virtual colonoscopy (VC) has shown a comparable performance to the gold-standard optical colonoscopy (OC) for detecting polyps of ..
- Long-Chain Fatty Acids, Oxidative Stress and Colorectal Neoplasm RiskHarvey J Murff; Fiscal Year: 2013..needed for the study have been collected as part of the on-going Tennessee Colorectal Polyp Study, the largest colonoscopy-based adenoma case-control study in the United States...
- Calcium/Vitamin D, Biomarkers & Colon Polyp PreventionRoberd Bostick; Fiscal Year: 2009..of normal-appearing rectal mucosa are being obtained from 1,328 of participants at their 3- or 5-year follow-up colonoscopy. Also, on a subset (n = 112) of these participants, biopsies of normal-appearing rectal mucosa are being taken "..
- Development of a Urine Test for the Early Detection of Colon CancerWei Song; Fiscal Year: 2012..Despite the availability of colonoscopy, the current standard of care for CRC screening, CRC remains the nation's second leading cause of cancer ..
- Eleventh Annual AACR International Conference on Frontiers in Cancer Prevention RMARGARET FOTI; Fiscal Year: 2012..Examples of this type of prevention include pap test (for cervical cancer), mammography (for breast cancer), colonoscopy (for colorectal cancer) and emerging new imaging techniques to detect breast and lung cancer...
- Impact of Family History of Colon Cancer on Adenomas in 40-49 Year OldsPhilip S Schoenfeld; Fiscal Year: 2012..advanced adenomas defined as adenomas >10 mm, villous adenomas, adenomas with high-grade dysplasia) during colonoscopy. Current guidelines from academic societies and VA Directives provide different recommendations about the need ..
- Optimizing Survivorship and Surveillance after Treatment for Colorectal CancerMARVELLA ELIZABETH FORD; Fiscal Year: 2012..e., office visits, carcionoembryonic antigen (CEA) tests, colonoscopy) or adherence to lifestyle-related surveillance guidelines for weight, exercise, alcohol and tobacco use...
- Colon Cancer Family Registry CohortNORALANE MOREY LINDOR; Fiscal Year: 2013..selected centers that are able to accomplish this in a cost-effective manner;and (ii) strategically collecting colonoscopy and pathology reports of colonic polyps when possible for high-risk participants (i.e...
- Great Lakes/New England Clinical Validation CenterDean E Brenner; Fiscal Year: 2013..stool DNA panel, and fecal immunochemical test (FIT) for the early detection of colorectal neoplasia using colonoscopy as the gold standard;2...
- Engineered imaging nanoparticles for real-time detection of cancer in the tumor bW David Lee; Fiscal Year: 2013..In a pilot study, we will also test our imaging technology to improve the detection of lesions during routine colonoscopy examination...
- Selenium Colorectal Cancer Chemoprevention TrialsPATRICIA ANN THOMPSON; Fiscal Year: 2013..Although most CRAs can be removed at colonoscopy, 20-50% of individuals undergoing repeat colonoscopy 3-5 years later have metachronous, i.e. new, CRAs...
- Analyses of Progression to Colon Cancer in a Spectrum of PathwaysWILLIAM FRANKLIN DOVE; Fiscal Year: 2012Observation of human colonic polyps by virtual colonoscopy has indicated several possible fates: regression, stasis, growth, or progression...
- Fecal Bacteriotherapy for Relapsing Clostridium difficile InfectionCOLLEEN RENEE KELLY; Fiscal Year: 2013..We propose to conduct a randomized, controlled clinical trial of FMT delivered at colonoscopy for treatment of relapsing CDI with the goal of establishing efficacy and safety data...
- Colorectal Neoplasia in SELECT ParticipantsM PETER LANCE; Fiscal Year: 2011..histopathology reports of SELECT participants who undergo lower gasatrointestinal endoscopy (sigmoidoscopy or colonoscopy) and removal of colorectal polyps as part of their usual clinical care while in the trial...
- INFLAMMATION, OBESITY AND RISK OF COLORECTAL ADENOMASRobert S Sandler; Fiscal Year: 2010..Blood samples will be collected immediately before routine colonoscopy and pinch biopsies of normal rectal mucosa will be collected during colonoscopy...
- Modifiers of Intestinal Tumor ProgressionLinda D Siracusa; Fiscal Year: 2012..Although the number of people having colonoscopy screenings is increasing, the incidence of colorectal cancer has not decreased...
- Tenth Annual AACR International Conference on Frontiers in Cancer Prevention ReseMARGARET FOTI; Fiscal Year: 2011..Examples of this type of prevention include colonoscopy and polypectomy...
- MODELING SPATIAL ACCESSIBILITY TO LOWER ENDOSCOPY SERVICES IN THE UNITED STATESMin Lian; Fiscal Year: 2013..Lower endoscopic examinations including flexible sigmoidoscopy and colonoscopy have been demonstrated to reduce the risks of incident CRC and CRC-specific mortality through detection and ..
- A Cohort Study of Sessile Serrated Polyps and Subsequent Colorectal NeoplasiaPolly A Newcomb; Fiscal Year: 2013..Men and women, aged 24-74, who received a baseline colonoscopy from 1998-2007 and had a clinical diagnosis of HPs (N=3,900) and a comparison group of colonoscopy patients ..
- Colon cancer disparity elimination: a faith-based participatory partnershipJohn R Ureda; Fiscal Year: 2012..have an adequate provider base to satisfy the increased demand resulting from this faith oriented barrier-free colonoscopy screening initiative...
- Racial Disparity in Colorectal Cancer: Molecular MechanismsADHIP N MAJUMDAR; Fiscal Year: 2013..specifically the proportion of CD44+CD166- phenotype, was markedly higher in colonic effluent, collected during colonoscopy, of AAs with adenomas than their CA counterparts...
- Conjoint analysis to measure physician discrimination toward African AmericansSarah Miller; Fiscal Year: 2013..e., colonoscopy, FOBT, FIT)...
- In Viro Detection of Neoplasia in the Digestive TractThomas D Wang; Fiscal Year: 2012..Peptides will be topically applied to the local mucosa via a spray catheter during routine screening colonoscopy to demonstrate the proof of concept of this novel imaging methodology for future applications that provide ..
- Training African American Peers as Patient Navigators for Colon Cancer ScreeningLina Jandorf; Fiscal Year: 2012..due to the preponderance of CRC in AAs beyond the reach of the flexible sigmoidoscopy, increased adherence to colonoscopy among AAs will save lives...
- IBDPROMISE: A Web-based Patient-centric Model to Improve Quality and OutcomesAshish Atreja; Fiscal Year: 2013..in which patients with inflammatory bowel disease (IBD) measure their quality of care metrics (such as colonoscopy surveillance) as well as quality of life in waiting rooms and at home;and physicians use this information at ..
- Biomarkers of Methionine Metabolism and Risk for Colorectal AdenomaMartha J Shrubsole; Fiscal Year: 2010..using plasma samples collected as part of the Tennessee Colorectal Polyp Study (TCPS;P50CA95103), an on-going colonoscopy-based case-control study of colorectal adenoma...
- Mitochondria proteome of ulcerative colitis associated dysplasiaRu Chen; Fiscal Year: 2013..knowledge for improved, more cost effective surveillance-to differentiate the subset of UC patients who need colonoscopy from those who do not...
- Measurement of Inappropriate Screening Tests (MIST)Melissa R Partin; Fiscal Year: 2013..that are shorter than recommended by guidelines, screening high-risk patients with a method other than colonoscopy, and screening when the patient is unlikely to benefit because they are under age 50 over age 85 or of have a ..
- Pretreatment Assessment of Cognitive and Immune Function in Individuals Newly DiaMoira Visovatti; Fiscal Year: 2013..newly diagnosed with CRC and a comparison group of 50 individuals without CRC having a negative screening colonoscopy. Objective measures of attention and memory;serum levels of pro-inflammatory cytokines and selected biomarkers ..
- Tailored Touchscreen Colorectal Cancer Prevention in Urban Core ClinicsK Allen Greiner; Fiscal Year: 2010..depending on stated preference, be offered either an immunochemical fecal occult blood test (iFOBT-lnSure"), colonoscopy, or sigmoidoscopy...
- Diet &Activity Community Trial: High-Risk Colon PolypsJames R Hebert; Fiscal Year: 2012..It also is the one most amenable to primary prevention by screening, with colonoscopy being the most effective screening procedure by far...
- Risk Factors for Asymptomatic DiverticulosisRobert S Sandler; Fiscal Year: 2013..characteristics of asymptomatic diverticulosis among a group of individuals undergoing first time screening colonoscopy. (2) To determine dietary and lifestyle risk factors for diverticulosis...
- Mitochondria as a novel biomarker of colorectal adenomaBharat Thyagarajan; Fiscal Year: 2013..in 392 colorectal adenoma cases and 565 controls collected from three methodologically very similar, colonoscopy-based case-control studies of incident, sporadic colorectal adenomas...
- High-resolution optical imaging assessment of microbicide toxicityMassoud Motamedi; Fiscal Year: 2011..Unfortunately, current imaging technology such as white light colposcopy or colonoscopy cannot provide high resolution images of epithelial injury and cannot probe below the surface where epithelial ..
- Patient Navigation for CRC Screening with Low-Income MinoritiesWilliam H Redd; Fiscal Year: 2011..Recent data indicate that the removal of precancerous polyps (via colonoscopy) decreases CRC incidence by 75-90 percent...
- Improving Flexible Sigmoidoscopy in Women by Optical Analysis of MicrovasculatureHEMANT K contact ROY; Fiscal Year: 2010..g. colonoscopy, CT colography) such as being relatively inexpensive, more widely available (performed by primary care ..
- Genetic interactions in colorectal cancer susceptibilityAmanda Ewart Toland; Fiscal Year: 2013..Since cancer mortality for CRC can be significantly reduced by the removal of precursor polyps during screening colonoscopy, identification of at risk individuals will decrease the incidence and mortality of this disease...
- Inhibition of Wnt/B-Catenin Signaling in Colorectal Cancer TherapyWei Chen; Fiscal Year: 2013..inhibitory activity of niclosamide in polyps will be evaluated histochemically after a run-in phase prior to colonoscopy. Given the long-standing efforts and gap in biochemical targets amenable to drug discovery, the finding that a ..
- Time lapse to cancer: defining transition from polyp to colorectal cancer (PQ14)LISA ALLYN BOARDMAN; Fiscal Year: 2013DESCRIPTION (provided by applicant): Colonoscopy screening is an effective intervention for identifying and removing precursor lesions for colorectal cancer (CRC). CRC has declined in incidence by 30% in the U.S...
- Chemoprevention of Colitis-Associated Neoplasia by 5-ASAMargie L Clapper; Fiscal Year: 2012..These data will be complemented by the use of MRI, colonoscopy and whole-body fluorescence imaging with biologically activated probes to monitor both the degree of ..
- Veteran and Staff Perceptions of VHA Large Scale Adverse Event CommunicationsANASHUA RANI ELWY; Fiscal Year: 2013..low), and different types of large scale adverse events (dental vs. colonoscopy) which will vary by the notification medium (phone call, letter or both from VHA facilities)...
- In Vivo Detection of Flat Colorectal Neoplasms with CT ColonographyJANNE JOHANNES NAPPI; Fiscal Year: 2010..were thought to be rare outside Japan, where they are reported relatively often on state-of-the-art optical colonoscopy (OC) examinations...
- Reducing VA No-Shows: Evaluation of Predictive Overbooking Applied to ColonoscopyBRENNAN MASON ROSS SPIEGEL; Fiscal Year: 2013..provided by applicant): Background: The VA has committed extensive resources to ensure that timely screening colonoscopy is readily available for eligible Veterans...
- Improving Gastrointestinal Disease Outcomes in Vulnerable PopulationsJOHN MATTHEW INADOMI; Fiscal Year: 2012..development of polyps in which subjects receive counseling about screening using fecal occult blood testing or colonoscopy or their choice of either test...
- Nanocytological Fecal Assessment to Personalize Colonoscopic SurveillanceHemant K Roy; Fiscal Year: 2013..The medico-legal and clinical consequences of interval CRCs lead to vast overuse of surveillance colonoscopy engendering unnecessary cost, complications etc...
- Comparative efficacy of water &indigo carmine vs water or air methodJoseph W Leung; Fiscal Year: 2013..Asymptomatic veterans referred for sedated colonoscopy for CRC screening at the Sacramento VAMC will be considered for enrollment. Over a 2...
- Circulating microRNA as a novel biomarker for inflammatory bowel diseaseADAM MATTHEW ZAHM; Fiscal Year: 2013..Due to a lack of conclusive biomarkers, the gold standard for diagnosis and evaluation of IBD is endoscopy/colonoscopy, although this invasive and costly procedure is associated with risks to the patient...
- Twelfth Annual AACR International Conference on Frontiers in Cancer Prevention ReMARGARET FOTI; Fiscal Year: 2013..Examples of this type of prevention include colonoscopy and polypectomy...
- Computerized Detection of Polyps in CT ColonographyHiroyuki Yoshida; Fiscal Year: 2013..Computed tomographic colonography (CTC), or virtual colonoscopy, has become an alternative technique for providing mass screening for colorectal carcinoma due to recent large-..
- Communication Patterns in Cancer Screening Navigation with African AmericansHayley S Thompson; Fiscal Year: 2010..through collaboration with a funded R01 parent study that is investigating the impact of PN on adherence to colonoscopy referral among AA primary care patients (R01- CA120658)...
- Cost-Effectiveness Analysis of Age-and Gender-Based Colorectal Cancer ScreeningNan Kong; Fiscal Year: 2013..The rationale for the proposed research is that by incorporating screening colonoscopy clinical data into CRC natural history modeling and comparing incremental cost-effectiveness ratios among ..
- Neoadjuvant photodynamic immunomodulation for colon cancerEdward L Nelson; Fiscal Year: 2011..the central hypothesis that it is safe and feasible to administer intraluminal PDT to colon cancers, via colonoscopy, in the neoadjuvant setting to induce localized tumor cell death and an inflammatory/immune response with an ..
- PEER OUTREACH TO FACILITATE COLORECTAL CANCER SCREENING IN SAFETY NET CLINICSAimee S James; Fiscal Year: 2010..The primary outcome of this study is completion of any acceptable CRC screen (FOBT, sigmoidoscopy, colonoscopy) at six-months after baseline, measured by chart review...
- Impact of a Novel Patient Educational Booklet on Colonoscopy QualityBRENNAN MASON ROSS SPIEGEL; Fiscal Year: 2013Impact of a Novel Patient Educational Booklet on Achievement of Quality Indicators in Screening Colonoscopy Project Summary/Abstract Project Background: Colorectal cancer (CRC) is the second leading cause of cancer death in the U.S...
- Vitamin D and Colorectal CancerRichard V Benya; Fiscal Year: 2012..In contrast, we use magnification chromo-colonoscopy (MCC) for CRC screening, allowing us to routinely enumerate ACF number in humans...
- Preclinical assay development of a novel Colon Cancer Marker (CCSA-4)JACK CLEMENS; Fiscal Year: 2007..of colon cancer, including fecal occult blood testing, flexible sigmoidoscopy, double contrast barium enema and colonoscopy. However, costs, risk of complications and discomfort have limited the general use of these methods...
- Improving Colonoscopy Quality through Automated MonitoringPiet C de Groen; Fiscal Year: 2010..b>Colonoscopy is currently the preferred screening modality for colorectal cancer...
- Colon Barrier Breakdown in the ElderlyJames Mullin; Fiscal Year: 2005..Aim 1: We will administer to consenting healthy patients undergoing colonoscopy cancer screening, a solution of either marmitol/lactulose or rbamuose/cellobiose to consume at bedtime...
- Managed Care Penetration and Cancer CareNancy Keating; Fiscal Year: 2003..for patients diagnosed with stage II or III rectal cancer; recommended surveillance activities (for example, colonoscopy within one year of diagnosis) for patients diagnosed with colorectal cancer; and PSA testing within one year of ..
- Quantifying Risk to Target Screening ColonoscopyThomas Imperiale; Fiscal Year: 2009DESCRIPTION (provided by applicant): Despite calls for universal colonoscopy (CY) for colorectal cancer (CRC) screening, its clinical application will be limited by issues of cost, safety, constrained resources, and patient acceptance...
- Cost-effectiveness of genetic screening for colon cancerSandeep Vijan; Fiscal Year: 2006..screening can improve the efficiency of screening programs by reducing demand for the limited resource of colonoscopy. Methods: Study Design: Simulation modeling...
- PROSPECTIVE COMPARISON OF COLONIC IMAGING TESTDon Rockey; Fiscal Year: 2001..The most common tests used to image the colon include air contrast barium enema and colonoscopy, each of which is associated with its own sets of benefits and limitations...
- Insulin Resistance and Adenomas of the ColorectumRALPH DAGOSTINO; Fiscal Year: 2003..All surviving cohort members (estimated 1518) will be invited to have a screening colonoscopy. Feasibility data indicate that 1000 will agree to have a colonoscopic exam, among whom we estimate 240 (range ..
- Insulin Resistance and Adenomas of the ColorectumTim Byers; Fiscal Year: 2003..All surviving cohort members (estimated 1518) will be invited to have a screening colonoscopy. Feasibility data indicate that 1000 will agree to have a colonoscopic exam, among whom we estimate 240 (range ..
- Insulin Resistance and Adenomas of the ColorectumSteven Haffner; Fiscal Year: 2003..All surviving cohort members (estimated 1518) will be invited to have a screening colonoscopy. Feasibility data indicate that 1000 will agree to have a colonoscopic exam, among whom we estimate 240 (range ..
- Insulin Resistance and Adenomas of the ColorectumMohammed Saad; Fiscal Year: 2003
- Insulin Resistance and Adenomas of the ColorectumTheodore Levin; Fiscal Year: 2003
- Oxidative Stress, DNA Repair & Colorectal Adenoma RiskMichael Goodman; Fiscal Year: 2009..biological samples and questionnaire data from a two previously conducted, and methodologically very similar, colonoscopy-based case-control studies of sporadic colorectal adenoma (Parent studies): one conducted in North Carolina and ..
- IMPROVING VIRTUAL COLONOSCOPY WITH COMPUTER DETECTIONPeter Santago; Fiscal Year: 2001..mortality, Congress recently included a provision in the Balanced Budget Act of 1997 to support screening colonoscopy as a means for early detection and removal of colorectal polyps, the precursors to cancer...
- EXPERIMENTAL AND CLINICAL STUDIES IN COLORECTAL CANCERThomas McGarrity; Fiscal Year: 1993..In a prospective study, biopsies of normal rectum, sigmoid and ascending colon will be obtained during colonoscopy. Regional differences in mucus glycoproteins (lectin binding), calcium activated proteins and cellular ..
- Increasing Colon Cancer Screening in Primary CareRonald Myers; Fiscal Year: 2004..screening regimens that are recommended include having a barium enema X-ray (BE) at five- year intervals or a colonoscopy (CX) every 10 years. Compliance with CRC screening guidelines is low...
- Colon Polyp Surveillance with DNA Analysis of StoolPhilip Schoenfeld; Fiscal Year: 2003..practice guidelines state that individuals with a history of colon adenomas should undergo surveillance colonoscopy to identify and remove newly formed colon adenomas...
- RECTAL MUCOSAL PROLIFERATION INDICES--EFFECTS OF CALCIUMJohn Baron; Fiscal Year: 1992..polyp immediately prior to entry, and have been judged free of remaining polyps in the large bowel by colonoscopy. They are randomized to receive either daily calcium carbonate supplementation (1200 mg calcium) or placebo, ..
- Critical evaluation of LPCs markers for colorectal cancerYan Xu; Fiscal Year: 2010..While colonoscopy has reported sensitivity and specificity values exceeding 95%, the degree of adherence is low due to the cost, ..
- Colonoscopy in Rural Oregon Practice (CROP)David Lieberman; Fiscal Year: 2009..Services Task Force recommends that all adults age 50 and older be screened for colorectal cancer with colonoscopy increasingly being utilized as the primary screening method...
- Colorectoral cancer screening decisions in primary careJames Dolan; Fiscal Year: 2006..occult blood tests and flexible sigmoidoscopy every 5 years, double contrast barium enema every 5 years, and colonoscopy every 10 years...