colectomy

Summary

Summary: Excision of a portion of the colon or of the whole colon. (Dorland, 28th ed)

Top Publications

  1. ncbi Laparoscopic vs. open colectomy in cancer patients: long-term complications, quality of life, and survival
    Marco Braga
    Department of Surgery, San Raffaele University, Milan, Italy
    Dis Colon Rectum 48:2217-23. 2005
  2. ncbi Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group
    David G Jayne
    Academic Unit of Surgery, St James s University Hospital, Leeds, United Kingdom
    J Clin Oncol 25:3061-8. 2007
  3. ncbi Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial
    Antonio M Lacy
    Department of Surgery, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, 08036 Barcelona, Spain
    Lancet 359:2224-9. 2002
  4. ncbi Single-incision versus standard multiport laparoscopic colectomy: a multicenter, case-controlled comparison
    Bradley J Champagne
    Case Medical Center, Cleveland, OH, USA
    Ann Surg 255:66-9. 2012
  5. ncbi Laparoscopic colectomy for cancer is not inferior to open surgery based on 5-year data from the COST Study Group trial
    James Fleshman
    Department of Surgery, Washington University School of Medicine, MO, and Department of General and Colorectal Surgery, St Joseph Mercy Hospital, MI, USA
    Ann Surg 246:655-62; discussion 662-4. 2007
  6. ncbi Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial
    Ruben Veldkamp
    Erasmus Medical Center, Rotterdam, Netherlands
    Lancet Oncol 6:477-84. 2005
  7. ncbi Oncologic results of laparoscopic versus conventional open surgery for stage II or III left-sided colon cancers: a randomized controlled trial
    Jin Tung Liang
    Department of Surgery, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan
    Ann Surg Oncol 14:109-17. 2007
  8. ncbi Early multi-institution experience with single-incision laparoscopic colectomy
    H Ross
    Riverview Medical Center, Red Bank, New Jersey 07701, USA
    Dis Colon Rectum 54:187-92. 2011
  9. ncbi Laparoscopic versus open surgery for rectal cancer: long-term oncologic results
    Christophe Laurent
    Department of Colorectal Surgery, Saint Andre Hospital, University of Bordeaux, Bordeaux 33075, France
    Ann Surg 250:54-61. 2009
  10. ncbi Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial
    Jane C Weeks
    Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    JAMA 287:321-8. 2002

Detail Information

Publications273 found, 100 shown here

  1. ncbi Laparoscopic vs. open colectomy in cancer patients: long-term complications, quality of life, and survival
    Marco Braga
    Department of Surgery, San Raffaele University, Milan, Italy
    Dis Colon Rectum 48:2217-23. 2005
    ..This study was designed to evaluate long-term complications, quality of life, and survival rate in a series of colorectal cancer patients randomized to laparoscopic or open surgery...
  2. ncbi Randomized trial of laparoscopic-assisted resection of colorectal carcinoma: 3-year results of the UK MRC CLASICC Trial Group
    David G Jayne
    Academic Unit of Surgery, St James s University Hospital, Leeds, United Kingdom
    J Clin Oncol 25:3061-8. 2007
    ..Few data are available on rectal cancer, and long-term data on survival and recurrence are now required...
  3. ncbi Laparoscopy-assisted colectomy versus open colectomy for treatment of non-metastatic colon cancer: a randomised trial
    Antonio M Lacy
    Department of Surgery, Institut de Malalties Digestives, Hospital Clinic, Institut d Investigacions Biomediques August Pi i Sunyer, University of Barcelona, 08036 Barcelona, Spain
    Lancet 359:2224-9. 2002
    Although early reports on laparoscopy-assisted colectomy (LAC) in patients with colon cancer suggested that it reduces perioperative morbidity, its influence on long-term results is unknown...
  4. ncbi Single-incision versus standard multiport laparoscopic colectomy: a multicenter, case-controlled comparison
    Bradley J Champagne
    Case Medical Center, Cleveland, OH, USA
    Ann Surg 255:66-9. 2012
    The aim of this study was to compare single-incision laparoscopic colectomy (SILC) to multiport laparoscopic colectomy (MLC) when performed by experienced laparoscopic surgeons.
  5. ncbi Laparoscopic colectomy for cancer is not inferior to open surgery based on 5-year data from the COST Study Group trial
    James Fleshman
    Department of Surgery, Washington University School of Medicine, MO, and Department of General and Colorectal Surgery, St Joseph Mercy Hospital, MI, USA
    Ann Surg 246:655-62; discussion 662-4. 2007
    ..high wound recurrence rates prompted a multi-institutional randomized trial to test the hypothesis that disease-free and overall survival are equivalent, regardless of whether patients receive laparoscopic-assisted or open colectomy.
  6. ncbi Laparoscopic surgery versus open surgery for colon cancer: short-term outcomes of a randomised trial
    Ruben Veldkamp
    Erasmus Medical Center, Rotterdam, Netherlands
    Lancet Oncol 6:477-84. 2005
    The safety and short-term benefits of laparoscopic colectomy for cancer remain debatable...
  7. ncbi Oncologic results of laparoscopic versus conventional open surgery for stage II or III left-sided colon cancers: a randomized controlled trial
    Jin Tung Liang
    Department of Surgery, National Taiwan University Hospital and College of Medicine, Taipei, Taiwan
    Ann Surg Oncol 14:109-17. 2007
    ..However, the oncologic outcome for cancer is still a concern. This study aims to compare the oncologic outcome between laparoscopic and open methods in the curative resection of Stage II or III left-sided colon cancers...
  8. ncbi Early multi-institution experience with single-incision laparoscopic colectomy
    H Ross
    Riverview Medical Center, Red Bank, New Jersey 07701, USA
    Dis Colon Rectum 54:187-92. 2011
    Single-incision laparoscopic colectomy represents a potential advance in minimally invasive surgical approaches to colorectal disease. Although widely promoted, outcome data are virtually absent...
  9. ncbi Laparoscopic versus open surgery for rectal cancer: long-term oncologic results
    Christophe Laurent
    Department of Colorectal Surgery, Saint Andre Hospital, University of Bordeaux, Bordeaux 33075, France
    Ann Surg 250:54-61. 2009
    ..The goal was to assess long-term oncologic outcome after laparoscopic versus open surgery for rectal cancer and to evaluate the impact of conversion...
  10. ncbi Short-term quality-of-life outcomes following laparoscopic-assisted colectomy vs open colectomy for colon cancer: a randomized trial
    Jane C Weeks
    Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA
    JAMA 287:321-8. 2002
    Laparoscopic-assisted colectomy (LAC) has emerged as the preferred minimally invasive surgical strategy for diseases of the colon...
  11. ncbi Single-port laparoscopy in colorectal surgery
    F H Remzi
    Department of Colorectal Surgery, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Colorectal Dis 10:823-6. 2008
    ....
  12. ncbi Laparoscopic resection of rectosigmoid carcinoma: prospective randomised trial
    Ka Lau Leung
    Department of Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong
    Lancet 363:1187-92. 2004
    ..We aimed to test the null hypothesis that there was no difference in survival after laparoscopic and open resection for rectosigmoid cancer...
  13. ncbi Single-incision laparoscopically assisted colectomy using standard laparoscopic instrumentation
    Nicholas A Rieger
    The Queen Elizabeth Hospital and The University of Adelaide, 11 Woodville Road, Woodville, South Australia 5011, Australia
    Surg Endosc 24:888-90. 2010
    ..A prospective case series of transumbilical single-incision laparoscopic colectomies using conventional laparoscopic trocars and instruments is described...
  14. ncbi Single port access laparoscopic right hemicolectomy
    Pascal Bucher
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Int J Colorectal Dis 23:1013-6. 2008
    ..We report in this paper a new technique of umbilical SPA right hemicolectomy with conventional surgical oncologic principle and technique of minimally invasive colectomy.
  15. ncbi Short-term outcomes of the Australasian randomized clinical study comparing laparoscopic and conventional open surgical treatments for colon cancer: the ALCCaS trial
    Peter J Hewett
    Division of Surgery, The Queen Elizabeth Hospital, Woodville South, Australia
    Ann Surg 248:728-38. 2008
    Laparoscopy has revolutionized many abdominal surgical procedures. Laparoscopic colectomy has become increasingly popular...
  16. ncbi Single-incision vs straight laparoscopic segmental colectomy: a case-controlled study
    B J Champagne
    Division of Colorectal Surgery, University Hospitals Case Medical Center, 11100 Euclid Avenue, Cleveland, OH 44106 5047, USA
    Dis Colon Rectum 54:183-6. 2011
    ..laparoscopic surgery is gaining momentum in general surgery but it is essentially unstudied for laparoscopic colectomy. The aim of our study was to compare outcomes for single-incision laparoscopic colectomy with laparoscopic-..
  17. pmc Anastomotic leakage is predictive of diminished survival after potentially curative resection for colorectal cancer
    Kenneth G Walker
    Department of Colorectal Surgery, University of Sydney, Concord Hospital, Sydney, Australia
    Ann Surg 240:255-9. 2004
    ..The aim of this study was to determine whether anastomotic leakage has an independent association with overall survival and cancer-specific survival...
  18. pmc Short-term and medium-term clinical outcomes of laparoscopic-assisted and open surgery for colorectal cancer: a single center retrospective case-control study
    Jing Sun
    Department of General Surgery, Rui Jin Hospital, Shanghai Jiao Tong University School of Medicine, 197 Rui Jin Er Road, Shanghai, 200025, China
    BMC Gastroenterol 11:85. 2011
    ..In this investigation we aim at assessing the diversities of short-term and medium-term clinical outcomes of laparoscopic-assisted versus open surgery for colorectal cancer...
  19. ncbi Hand-assisted laparoscopic colectomy vs open colectomy: a prospective randomized study
    J C Kang
    Division of Colorectal Surgery, Tri Service General Hospital, National Defense Medical Center, 325 Section 2, Cheng Kong Road, Nei Hu Dis 114, Taipei, Taiwan, ROC
    Surg Endosc 18:577-81. 2004
    We compared the perioperative parameters and outcomes achieved with hand-assisted laparoscopic colectomy (HALC) vs open colectomy (OC) for the management of benign and malignant colorectal disease, including cancer patients treated with ..
  20. ncbi Primary colectomy in patients with stage IV colon cancer and unresectable distant metastases improves overall survival: results of a multicentric study
    Mehdi Karoui
    Department of GI Oncology and Laboratory of Clinical Investigation 4393, Universite Paris Est Créteil UPEC, Creteil, France
    Dis Colon Rectum 54:930-8. 2011
    Whether patients with stage IV colon cancer and unresectable distant metastases should be managed by primary colectomy followed by chemotherapy or immediate chemotherapy without resection of the primary tumor is still controversial.
  21. pmc Functional recovery after open versus laparoscopic colonic resection: a randomized, blinded study
    Linda Basse
    Department of Surgical Gastroenterology, Copenhagen University Hospital, Hvidovre, Kettegaard Alle 30, DK 2650 Hvidovre, Denmark
    Ann Surg 241:416-23. 2005
    ..Since no comparative data between laparoscopic and open colonic resection with multimodal rehabilitation are available, the value of laparoscopy per se is unknown...
  22. ncbi Long-term consequences of not closing the mesenteric defect after laparoscopic right colectomy
    Jennifer C Cabot
    Section of Colon and Rectal Surgery, Department of Surgery, New York Presbyterian Hospital Columbia Campus, New York, New York 10032, USA
    Dis Colon Rectum 53:289-92. 2010
    The controversy regarding closing the mesenteric defect after laparoscopic right colectomy remains a subject of debate. This study describes the consequences of not closing the mesenteric defect.
  23. ncbi Single incision ("scarless") laparoscopic total abdominal colectomy with end ileostomy for ulcerative colitis
    Alessandro Fichera
    Department of Surgery, University of Chicago Medical Center, 5841 S Maryland Ave, MC 5095, Chicago, IL 60637, USA
    J Gastrointest Surg 15:1247-51. 2011
    Total abdominal colectomy with ileal pouch-anal anastomosis is the intervention of choice for patients with medically uncontrolled ulcerative colitis. A three-stage approach is preferred in particularly debilitated patients...
  24. ncbi Papillary adenocarcinoma arising in a duplication of the cecum
    Jiwon Lee
    Department of Radiology, Kangwon National University College of Medicine, 192 1 Hyoja 2 Dong, Chuncheon si, Kangwon Do, 200 701, South Korea
    Abdom Imaging 33:601-3. 2008
    ..We describe a papillary adenocarcinoma, arising from a duplication of the colon, seen as a cyst with an enhancing papillary projection nodule located adjacent to the wall of the ascending colon and cecum on computed tomography...
  25. ncbi Single-incision laparoscopic right hemicolectomy for a colon mass
    Aziz M Merchant
    Department of Surgery, Emory Endosurgery Unit, Emory University, Atlanta, Georgia 30322, USA
    Dis Colon Rectum 52:1021-4. 2009
    ..Single-incision laparoscopy is being performed for a wide variety of procedures. We describe our technique of single-incision laparoscopic right hemicolectomy for a colon mass...
  26. ncbi Laparoendoscopic single-site surgery is feasible in complex colorectal resections and could enable day case colectomy
    K J Gash
    North Bristol NHS Trust, Frenchay Hospital, Bristol, BS16 1LE, UK
    Surg Endosc 25:835-40. 2011
    ..This report describes the largest case series of LESS colorectal surgery and its effects on recovery...
  27. ncbi The long-term results of a randomized clinical trial of laparoscopy-assisted versus open surgery for colon cancer
    Antonio M Lacy
    Department of Surgery, Centro de Investigaciones Biomédicas Esther Koplowitz, IMDiM, IDIBAPS, Hospital Clinic, University of Barcelona, Spain
    Ann Surg 248:1-7. 2008
    The aim of this study was to compare the long-term outcome of laparoscopy-assisted colectomy (LAC) and open colectomy (OC) for nonmetastatic colon cancer.
  28. ncbi Robotic-assisted single-incision right colectomy: early experience
    Matthew B Ostrowitz
    Department of Surgery, North Shore University Hospital, Manhasset, NY, USA
    Int J Med Robot 5:465-70. 2009
    ..We describe our early experience with three robotic single-incision right hemicolectomies...
  29. ncbi Single-incision laparoscopic colectomy: early experience
    Wai Lun Law
    Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    Dis Colon Rectum 53:284-8. 2010
    ..Its application in colectomy has been published only in case reports...
  30. ncbi Single-incision laparoscopic surgery (SILS) in complex colorectal surgery: a technique offering potential and not just cosmesis
    W M Chambers
    SPIRE Bristol Hospital, Bristol, UK
    Colorectal Dis 13:393-8. 2011
    ..The literature contains two reports of SILS right hemicolectomy, and we report our experience of this technique...
  31. ncbi Single-access laparoscopic sigmoidectomy as definitive surgical management of prior diverticulitis in a human patient
    Joel Leroy
    Department of Surgery, Institut de Recherche contre les Cancers de l Appareil Digestif European Institute of TeleSurgery, Strasbourg, France
    Arch Surg 144:173-9; discussion 179. 2009
    ..It is enhanced by both innovative port technology and technical expertise learned by developing natural orifice transluminal endoscopic surgery (NOTES)...
  32. ncbi Single-incision laparoscopic right colectomy: experience with 17 consecutive cases and comparison with multiport laparoscopic right colectomy
    James Adair
    Department of Surgery, Section of Minimally Invasive Surgery, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA
    Dis Colon Rectum 53:1549-54. 2010
    ..However, there have been a limited number of reports of single-incision procedures in colorectal disease...
  33. ncbi Single incision laparoscopic right colectomy
    Luigi Boni
    Minimally Invasive Surgery Research Center, Department of Surgical Sciences, University of Insubria Azienda Ospedaliera Macchi, Viale Borri n 57, 21100, Varese, Italy
    Surg Endosc 24:3233-6. 2010
    This study was designed to describe the surgical technique for single-incision laparoscopic right colectomy and present preliminary short-term results...
  34. ncbi Prospective multicenter trial of staging adequacy in colon cancer: preliminary results
    Anton J Bilchik
    John Wayne Cancer Institute and Saint Johns Health Center, Santa Monica, CA 90404, USA
    Arch Surg 141:527-33; discussion 533-4. 2006
    ..A 25% recurrence rate in patients with node-negative CRC suggests that current staging practices are inadequate. Focused analysis of the sentinel node (SN) by multiple sectioning and immunohistochemistry improves staging accuracy...
  35. ncbi Laparoscopic total colectomy for acute colitis: a case-control study
    P W Marcello
    Department of Colon and Rectal Surgery, Labey Clinic, Burlington, Massachusetts, USA
    Dis Colon Rectum 44:1441-5. 2001
    INTRODUCTION: There are no previous comparative studies of total abdominal colectomy by laparoscopic methods in ulcerative colitis and Crohn's disease patients requiring urgent colectomy...
  36. ncbi Impact of conversion on the long-term outcome in laparoscopic resection of colorectal cancer
    Albert C Y Chan
    Department of Surgery, Queen Mary Hospital, University of Hong Kong Medical Centre, Pokfulam Road, Kowloon, Hong Kong
    Surg Endosc 22:2625-30. 2008
    ..This study aimed to evaluate the impact of conversion on the operative outcome and survival of patients who underwent laparoscopic resection for colorectal malignancy...
  37. ncbi Randomized clinical trial of multimodal optimization and standard perioperative surgical care
    A D G Anderson
    Combined Gastroenterology Unit, Scarborough Hospital, Woodlands Drive, Scarborough YO12 6QL, UK
    Br J Surg 90:1497-504. 2003
    ..The aim of this randomized trial was to compare multimodal optimization with standard care in patients undergoing colonic resection...
  38. ncbi Five-year follow-up of the Medical Research Council CLASICC trial of laparoscopically assisted versus open surgery for colorectal cancer
    D G Jayne
    Section of Translational Anaesthesia and Surgery, Leeds Institute of Molecular Medicine, St James s University Hospital, Leeds, UK
    Br J Surg 97:1638-45. 2010
    ..The UK Medical Research Council CLASICC trial assessed the safety and efficacy of laparoscopically assisted surgery in comparison with open surgery for colorectal cancer. The results of the 5-year follow-up analysis are presented...
  39. ncbi Diverting loop ileostomy and colonic lavage: an alternative to total abdominal colectomy for the treatment of severe, complicated Clostridium difficile associated disease
    Matthew D Neal
    Department of Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Ann Surg 254:423-7; discussion 427-9. 2011
    To determine whether a minimally invasive, colon-preserving approach could serve as an alternative to total colectomy in the treatment of severe, complicated Clostridium difficile-associated disease (CDAD).
  40. ncbi Readmission rates and cost following colorectal surgery
    Elizabeth C Wick
    Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    Dis Colon Rectum 54:1475-9. 2011
    ..Hospital readmission is emerging as a quality indicator by the state, federal, and private payors with the goal of denying payment for select readmissions...
  41. ncbi Prospective randomized trial comparing conventional laparoscopic colectomy with hand-assisted laparoscopic colectomy: applicability, immediate clinical outcome, inflammatory response, and cost
    E M Targarona
    Department of General and Digestive Surgery, Hospital de Sant Pau, Autonomous University of Barcelona, C Padre Claret 167, 08025 Barcelona, Spain
    Surg Endosc 16:234-9. 2002
    ..Therefore, we set out to study the applicability, immediate clinical outcome, inflammatory response, and cost of HALS compared with conventional LS using colectomy as a model.
  42. ncbi Robotic versus laparoscopic colectomy
    A L Rawlings
    Division of Minimally Invasive Surgery, Department of Surgery, University of Illinois College of Medicine at Peoria, 420 NE Glen Oak Avenue, Suite 301, Peoria, IL 61603, USA
    Surg Endosc 21:1701-8. 2007
    ..This study compared the experience and cost of the DaVinci Robotic system and laparoscopy for colon resections...
  43. ncbi Single-incision versus conventional laparoscopic sigmoid colectomy: a case-matched series
    Diego I Ramos-Valadez
    Division of Minimally Invasive Colon and Rectal Surgery, Department of Surgery, University of Texas Medical School at Houston, 7900 Fannin Street, Suite 2700, Houston, TX 77054, USA
    Surg Endosc 26:96-102. 2012
    ..We evaluated the efficacy of single-incision laparoscopic colectomy (SILC) for the treatment of sigmoid disease through a matched-case comparison with conventional laparoscopic ..
  44. ncbi Quality of life in colorectal cancer patients with colectomy and the validation of the Functional Assessment of Cancer Therapy-Colorectal (FACT-C), Version 4
    Hee Jung Yoo
    Department of Psychiatry, Asan Medical Center, Ulsan University College of Medicine, Seoul, Korea
    J Pain Symptom Manage 30:24-32. 2005
    ..the assessment at baseline and 52 of these patients completed the instrument at one month and six months after colectomy. In addition to the FACT-C, the shortened forms of the Profile of Mood States, the Eastern Cooperative Oncology ..
  45. ncbi Single-incision versus conventional laparoscopic colectomy for colonic neoplasm: a randomized, controlled trial
    Jensen T C Poon
    Division of Colorectal Surgery, Department of Surgery, Queen Mary Hospital, The University of Hong Kong, 102 Pok Fu Lam Road, Hong Kong, Hong Kong
    Surg Endosc 26:2729-34. 2012
    Single-incision laparoscopic colectomy (SILC) is a newly developed procedure with the benefit of better cosmetic outcome and potentially reduced wound pain compared with conventionally laparoscopic colectomy (CLC)...
  46. ncbi Laparoscopic colorectal surgery: a better look into the latest trends
    Celeste Y Kang
    Department of Surgery, University of California, Irvine School of Medicine, Irvine, CA, USA
    Arch Surg 147:724-31. 2012
    ..This study evaluates LCRS trends before and after the application of specific codes for LCRS...
  47. ncbi Single-port laparoscopic right hemicolectomy: a safe alternative to conventional laparoscopy
    Joshua A Waters
    Indiana University Department of Surgery, Indianapolis, Indiana, USA
    Dis Colon Rectum 53:1467-72. 2010
    ..Limited data exist comparing single-port with conventional laparoscopy for right colectomy. Our aim is to compare single-port with laparoscopic colectomy with regard to safety and feasibility...
  48. ncbi Hospital variation in 30-day mortality after colorectal cancer surgery in denmark: the contribution of hospital volume and patient characteristics
    Merete Osler
    Research Center for Prevention and Health, Glostrup University Hospital, Denmark
    Ann Surg 253:733-8. 2011
    ..This study examines variation between hospitals in 30-day mortality after surgery for colorectal cancer (CRC) in Denmark and explores whether hospital volume and patient characteristics contribute to any variation between hospitals...
  49. ncbi Prospective randomised study to evaluate the use of DERMABOND ProPen (2-octylcyanoacrylate) in the closure of abdominal wounds versus closure with skin staples in patients undergoing elective colectomy
    Julian Ong
    Department of Colorectal Surgery, Singapore General Hospital, Singapore, Singapore
    Int J Colorectal Dis 25:899-905. 2010
    ..The use of 2-OCA in the closure of abdominal laparotomy wounds has not been thoroughly evaluated. Our aim was to compare 2-OCA with conventional skin stapling devices in colorectal surgery...
  50. ncbi Laparoscopy decreases postoperative complication rates after abdominal colectomy: results from the national surgical quality improvement program
    Gregory D Kennedy
    Colon and Rectal Surgery, Department of Surgery, University of Wisconsin SMPH, Madison, WI 53792, USA
    Ann Surg 249:596-601. 2009
    ..Compare outcomes of non-emergent laparoscopic to open colon surgery...
  51. pmc Teaching hospital status and operative mortality in the United States: tipping point in the volume-outcome relationship following colon resections?
    Awori J Hayanga
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Arch Surg 145:346-50. 2010
    ..To compare risk- and volume-adjusted outcomes of colon resections performed at teaching hospitals (THs) vs non-THs to assess whether benign disease may influence the volume-outcome effect...
  52. ncbi Nonelective excisional colorectal surgery in English National Health Service Trusts: a study of outcomes from Hospital Episode Statistics Data between 1996 and 2007
    Omar Faiz
    Department of Colorectal Surgery, St Mark s Hospital, Middlesex, UK
    J Am Coll Surg 210:390-401. 2010
    ..This study sought to describe the practice of emergency colorectal surgery in the United Kingdom during an 11-year period using the Hospital Episode Statistics (HES) database...
  53. ncbi Outcomes and costs of elective surgery for diverticular disease: a comparison with other diseases requiring colectomy
    Kyle J Van Arendonk
    Department of Surgery, The Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    JAMA Surg 148:316-21. 2013
    To compare outcomes and costs of elective surgery for diverticular disease (DD) with those of other diseases commonly requiring colectomy.
  54. ncbi Intra-abdominal desmoid tumor mimicking locoregional recurrence after colectomy in a patient with sporadic colon cancer: report of a case
    Rei Mizuno
    Gastroenterological Center, Department of Gastroenterological Surgery, Cancer Institute Hospital, 3 10 6 Ariake, Koto ku, Tokyo, 135 8550, Japan
    Surg Today 41:730-2. 2011
    ..The patient remains well 24 months after his last operation. Differentiating between the desmoid tumor and locoregional recurrent tumor was difficult, and surgical resection was the optimal treatment...
  55. ncbi A comparison of epidural analgesia and traditional pain management effects on survival and cancer recurrence after colectomy: a population-based study
    Kenneth C Cummings
    Department of General Anesthesiology, Anesthesiology Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Anesthesiology 116:797-806. 2012
    ..This study compared survival and cancer recurrence rates for resection of colorectal cancer between patients who received perioperative epidurals and those who did not...
  56. ncbi Postoperative complications and mortality following colectomy for ulcerative colitis
    Shanika De Silva
    Inflammatory Bowel Disease Clinic, University of Calgary, Calgary, Alberta, Canada
    Clin Gastroenterol Hepatol 9:972-80. 2011
    Complications after colectomy for ulcerative colitis (UC) have not been well characterized in large, population-based studies...
  57. ncbi Randomized clinical trial of robot-assisted versus standard laparoscopic right colectomy
    J S Park
    Colorectal Cancer Centre, Kyungpook National University Medical Centre, School of Medicine, Kyungpook National University, 474 Hakjeongdong, Buk Gu, Daegu 702 210, Korea
    Br J Surg 99:1219-26. 2012
    ..However, it is unclear whether robot-assisted colectomy (RAC) has significant clinical advantages over laparoscopically assisted colectomy (LAC) in treating colonic ..
  58. ncbi A comparison of short-term outcome after laparoscopic, transverse, and midline right-sided colectomy
    E Tanis
    Department of Surgery, Tergooiziekenhuizen, P O Box 10016, 1201 DA, Hilversum, The Netherlands
    Int J Colorectal Dis 27:797-802. 2012
    ..The aim of the present study was to compare the laparoscopy, transverse, and midline laparotomy in right-sided colectomies with respect to short- and long-term outcome...
  59. ncbi Single-incision laparoscopic colectomy for cancer: assessment of oncologic resection and short-term outcomes in a case-matched comparison with standard laparoscopy
    Harry T Papaconstantinou
    Department of Surgery, Section of Colon and Rectal Surgery, Scott and White Memorial Hospital and Clinic, Texas A and M University System Health Science Center College of Medicine, Temple, TX 76508, USA
    Surgery 150:820-7. 2011
    To compare single-incision laparoscopic (SIL) with multiport laparoscopic (LAP) colectomy in patients with colon cancer to assess oncologic resection and 1-year outcomes.
  60. ncbi Single-incision laparoscopic surgery for ileocolic resection in Crohn's disease
    Emile Rijcken
    Department of General and Visceral Surgery, Muenster University Hospital, Waldeyerstrasse 1, Muenster, Germany
    Dis Colon Rectum 55:140-6. 2012
    ..Single-incision laparoscopic surgery is a development in the field of minimally invasive surgery that is being increasingly used for colorectal procedures...
  61. ncbi Intravenous lidocaine infusion facilitates acute rehabilitation after laparoscopic colectomy
    Abdourahamane Kaba
    Department of Anesthesia and Intensive Care Medicine, Centre Hospitalier Universitaire CHU de Liège, University of Liege, Belgium
    Anesthesiology 106:11-8; discussion 5-6. 2007
    ..The authors therefore tested the hypothesis that perioperative lidocaine infusion facilitates acute rehabilitation protocol in patients undergoing laparoscopic colectomy.
  62. pmc Predicting survival after curative colectomy for cancer: individualizing colon cancer staging
    Martin R Weiser
    Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
    J Clin Oncol 29:4796-802. 2011
    ..The purpose of this study was to extend the seventh edition of the AJCC staging system for colon cancer to incorporate additional information available from tumor registries, thereby improving prognostic accuracy...
  63. ncbi Single incision laparoscopic total abdominal colectomy with ileorectal anastomosis for synchronous colon cancer
    O Bardakcioglu
    Section of Colon and Rectal Surgery, Department of Surgery, Saint Louis University, 3635 Vista Ave, Desloge Tower 3rd Floor, Saint Louis, MO 63110, USA
    Tech Coloproctol 14:257-61. 2010
    ..A single incision laparoscopic total abdominal colectomy with an ileorectal anastomosis and intraoperative CO(2) colonoscopy was performed for a patient with synchronous ..
  64. ncbi Single-port laparoscopic total colectomy for medically uncontrolled colitis
    Ronan A Cahill
    Department of Colorectal Surgery, John Radcliffe and Churchill Hospitals, Oxford, United Kingdom
    Dis Colon Rectum 53:1143-7. 2010
    ..Here, we detail how laparoscopic total colectomy can be safely performed within the constraints of such single site operating.
  65. ncbi Single incision laparoscopic left colectomy for carcinoma of distal transverse colon
    W L Law
    Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong
    Colorectal Dis 12:698-701. 2010
    We report a single-incision laparoscopic left colectomy for a patient with a distal transverse colon cancer.
  66. ncbi Single-incision laparoscopic colectomy: outcomes of an emerging minimally invasive technique
    Diego I Ramos-Valadez
    Division of Minimally Invasive Colon and Rectal Surgery, Department of Surgery, University of Texas Medical School at Houston, 7900 Fannin Street, Suite 2700, Houston, TX 77054, USA
    Int J Colorectal Dis 26:761-7. 2011
    Single-incision laparoscopic colectomy (SILC) is an emerging procedure in the field of minimally invasive colon and rectal surgery. The purpose of this study was to evaluate the safety and feasibility of this procedure.
  67. ncbi Single-incision laparoscopic colectomy for malignant disease
    Megan E McNally
    Department of Surgery, University of Missouri Kansas City, Kansas City, MO 64110, USA
    Surg Endosc 25:3559-65. 2011
    Laparoscopic colectomy has been shown to confer equivalent disease-free and overall survival compared to traditional open colectomy. Patients experience benefit in length of hospital stay as well as diminished narcotic use...
  68. ncbi Management of the rectal stump after emergency sub-total colectomy: which surgical option is associated with the lowest morbidity?
    J P Trickett
    Department of Colorectal Surgery, Frimley Park Hospital, Frimley, UK
    Colorectal Dis 7:519-22. 2005
    To identify the preferred surgical management of the rectal stump after emergency subtotal colectomy (ESC) for acute severe colitis by assessing the morbidity associated with each option.
  69. pmc Bowel preparation for colectomy and risk of Clostridium difficile infection
    GRETA L KRAPOHL
    School of Nursing, University of Michigan, Ann Arbor, Michigan, USA
    Dis Colon Rectum 54:810-7. 2011
    Mechanical bowel preparation before colectomy is controversial for several reasons, including a theoretically increased risk of Clostridium difficile infection.
  70. ncbi Outcomes for case-matched single-port colectomy are comparable with conventional laparoscopic colectomy
    A M Wolthuis
    Department of Abdominal Surgery, University Hospital Gasthuisberg, and Belgium Interuniversity Centre for Biostatistics and Statistical Bioinformatics, Leuven, Belgium
    Colorectal Dis 14:634-41. 2012
    ..The aim of this study was to compare early outcomes of single-port colectomy with those of conventional laparoscopic colectomy.
  71. ncbi Laparoscopically assisted colectomy: a study of risk factors and predictors of open conversion
    P Y Tan
    Colorectal Unit, Division of Surgery, The Queen Elizabeth Hospital, 28 Woodville Road, Woodville South, SA, 5011, Australia
    Surg Endosc 22:1708-14. 2008
    ..This study aimed to audit the authors' experience with laparoscopically assisted colectomy and to assess the clinical outcomes of patients undergoing conversion.
  72. ncbi Medical and surgical management of chronic ulcerative colitis
    Robert R Cima
    Division of Colon and Rectal Surgery, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
    Arch Surg 140:300-10. 2005
  73. ncbi Single-incision laparoscopic versus conventional laparoscopic right hemicolectomy: a comparison of short-term surgical results
    William Tzu Liang Chen
    Division of Colorectal Surgery, Department of Surgery, Center of Minimally Invasive Surgery, China Medical University Hospital, China Medical University, No 2, Yu Der Road, Taichung, 404, Taiwan
    Surg Endosc 25:1887-92. 2011
    Since the introduction of laparoscopic colectomy, improved short-term surgical results have been noted in the literature...
  74. ncbi Surgical management of mesenteric lymph node metastasis in patients undergoing rectosigmoid colectomy for locally advanced ovarian carcinoma
    Ritu Salani
    The Kelly Gynecologic Oncology Service, Department of Gynecology and Obstetrics, The Sidney Kimmel Comprehensive Cancer Center, The Johns Hopkins Medical Institutions, 600 N Wolfe St Phipps 281, Baltimore, Maryland 21224, USA
    Ann Surg Oncol 14:3552-7. 2007
    ....
  75. ncbi Subtotal colectomy for severe acute colitis: a 20-year experience of a tertiary care center with an aggressive and early surgical policy
    Arnaud Alves
    Department of Surgery, Lariboisiere Hospital, Paris, France
    J Am Coll Surg 197:379-85. 2003
    ..The aim of this study was to report a 20-year experience with subtotal colectomy (STC) performed for SAC.
  76. ncbi Laparoscopic colectomy for Crohn's colitis. A large prospective comparative study
    Konstantin Umanskiy
    Department of Surgery, MC 5095, University of Chicago Hospitals, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    J Gastrointest Surg 14:658-63. 2010
    The purpose of this study was to compare short-term outcomes of laparoscopic (LC) vs open colectomy (OC) in patients with Crohn's colitis.
  77. ncbi Impact of hospital volume on postoperative morbidity and mortality following a colectomy for ulcerative colitis
    Gilaad G Kaplan
    Inflammatory Bowel Disease Clinic, University of Calgary, Calgary, Alberta, Canada
    Gastroenterology 134:680-7. 2008
    Postoperative morbidity and mortality following a colectomy for ulcerative colitis (UC) has been primarily reported from tertiary care referral centers that perform a high volume of operations; however, the postoperative outcomes among ..
  78. ncbi Single-incision laparoscopic right hemicolectomy: safety and feasibility in a series of consecutive cases
    Diego I Ramos-Valadez
    Division of Minimally Invasive Colon and Rectal Surgery, Department of Surgery, University of Texas Medical School at Houston, 7900 Fannin Street, Suite 2700, Houston, TX 77054, USA
    Surg Endosc 24:2613-6. 2010
    Single-incision laparoscopic colectomy (SILC) is rapidly emerging in the field of minimally invasive colon and rectal surgery...
  79. ncbi Prognostic impact of micrometastases in colon cancer: interim results of a prospective multicenter trial
    Anton J Bilchik
    Department of Gastrointestinal Oncology, John Wayne Cancer Institute at Saint John s Health Center, Santa Monica, CA 90404, and Michigan State University McLaren Regional Medical Center, Flint, MI, USA
    Ann Surg 246:568-75; discussion 575-7. 2007
    ..6% rate of micrometastases (MM) identified by immunohistochemical staining (IHC) of H&E-negative SNs in CC. We hypothesized that these MM have prognostic importance...
  80. ncbi Laparoscopic-assisted vs. open colectomy for colon cancer: a prospective randomized trial
    Andreas M Kaiser
    Department of Colorectal Surgery, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    J Laparoendosc Adv Surg Tech A 14:329-34. 2004
    Although laparoscopic-assisted colectomy (LAC) has evolved as a technical option in the treatment of benign colonic diseases, its role in the treatment of malignancies remains controversial...
  81. ncbi Hand-assisted laparoscopic colectomy: the learning curve is for operative speed, not for quality
    E Ozturk
    Department of Colon and Rectal Surgery, Cleveland Clinic, Cleveland, Ohio 44195, USA
    Colorectal Dis 12:e304-9. 2010
    We aimed to define the learning curve for hand-assisted laparoscopic colectomy (HALC).
  82. ncbi Single-incision laparoscopic right colectomy: a case-matched comparison with standard laparoscopic and hand-assisted laparoscopic techniques
    Harry T Papaconstantinou
    Department of Surgery, Section of Colon and Rectal Surgery, Scott and White Memorial Hospital and Clinic, Texas A and M University System Health Science Center College of Medicine, Temple, TX 76508, USA
    J Am Coll Surg 213:72-80; discussion 80-2. 2011
    Single-incision laparoscopic (SIL) colectomy is an advance in minimally invasive colorectal surgical techniques. Feasibility and safety of SIL colectomy has been reported; however, benefits and outcomes are not well-defined...
  83. pmc The ladies trial: laparoscopic peritoneal lavage or resection for purulent peritonitis and Hartmann's procedure or resection with primary anastomosis for purulent or faecal peritonitis in perforated diverticulitis (NTR2037)
    Hilko A Swank
    Department of Surgery, Academic Medical Centre, Amsterdam, The Netherlands
    BMC Surg 10:29. 2010
    ....
  84. ncbi Consequences of conversion in laparoscopic colorectal surgery
    Rodrigo Gonzalez
    Emory Endosurgery Unit, Emory University School of Medicine, Atlanta, Georgia, USA
    Dis Colon Rectum 49:197-204. 2006
    ..Laparoscopic colorectal resections have relatively high conversion rates compared with other laparoscopic procedures. This study was designed to evaluate outcomes of conversions compared with laparoscopic and open colorectal resections...
  85. pmc Defunctioning stoma reduces symptomatic anastomotic leakage after low anterior resection of the rectum for cancer: a randomized multicenter trial
    Peter Matthiessen
    Department of Surgery, Orebro University Hospital, Orebro, Sweden
    Ann Surg 246:207-14. 2007
    ....
  86. ncbi Further reduction of hospital stay for laparoscopic colon resection by modifications of the fast-track care plan
    Gavish N Patel
    Department of Surgery, University of Illinois College of Medicine at Peoria, 624 Glen Oak Ave, Peoria, IL 61603, USA
    Am J Surg 199:391-4; discussion 394-5. 2010
    Fast-track surgery has been described as a plan to facilitate early recovery. We present one surgeon's modifications to fast-track surgery for laparoscopic colectomy patients.
  87. ncbi Predictors of mortality after colectomy for fulminant Clostridium difficile colitis
    John C Byrn
    Department of Surgery, Mount Sinai School of Medicine, 5 E 98th St, 15th Floor, Box 1259, New York, NY 10029, USA
    Arch Surg 143:150-4; discussion 155. 2008
    To present, to our knowledge, the largest experience with colectomy for fulminant Clostridium difficile colitis and to propose factors significant in predicting mortality.
  88. ncbi Endolaparoscopic approach vs conventional open surgery in the treatment of obstructing left-sided colon cancer: a randomized controlled trial
    Hester Yui Shan Cheung
    Department of Surgery, Pamela Youde Nethersole Eastern Hospital, Chai Wan, Hong Kong, China
    Arch Surg 144:1127-32. 2009
    ..To compare self-expanding metal stents with emergency open surgery in the treatment of obstructing left-sided colon cancer...
  89. ncbi 'Fast-track' multimodal rehabilitation program improves outcome after laparoscopic sigmoidectomy: a controlled prospective evaluation
    W Raue
    Department of General, Visceral, Vascular, and Thoracic Surgery, Medical Faculty, Humboldt University, Charite, Campus Mitte, Schumannstrasse 20 21, 10117, Berlin, Germany
    Surg Endosc 18:1463-8. 2004
    ....
  90. ncbi Can elderly patients with colorectal cancer tolerate planned surgical treatment? A practical approach to a common dilemma
    G Ugolini
    Department of General Surgery, Emergency Surgery and Organ Transplantation, University of Bologna, Policlinico S Orsola Malpighi, Bologna, Italy
    Colorectal Dis 11:750-5. 2009
    ....
  91. ncbi Economic burden of postoperative ileus associated with colectomy in the United States
    Shrividya Iyer
    Wyeth Pharmaceuticals, 500 Arcola Road, Collegeville, PA 19403, USA
    J Manag Care Pharm 15:485-94. 2009
    ..b>Colectomy surgery patients who develop postoperative ileus could have greater health care resource utilization, including ..
  92. pmc Length of stay: an inappropriate readout of the success of enhanced recovery programs
    J M C Maessen
    Department of Surgery, University Hospital Maastricht, PO Box 5800, 6202 AZ, Maastricht, The Netherlands
    World J Surg 32:971-5. 2008
    ..This study was designed to assess the influence of an ERAS program on the proportion, appropriateness, and extent of delay in discharge...
  93. ncbi Single-port access laparoscopic radical left colectomy in humans
    Pascal Bucher
    Department of Surgery, University Hospital Geneva, Geneva, Switzerland
    Dis Colon Rectum 52:1797-801. 2009
    ..We report our experience with the first transumbilical single-port access radical left colectomy conforming to surgical oncologic principle and minimally invasive colectomy technique.
  94. ncbi Hand-assisted laparoscopic versus open right colectomy: a randomized controlled trial
    Chi Chiu Chung
    Department of Surgery, Pamela Youde Nethersole Eastern Hospital, 3 Lok Man Road, Chai Wan, Hong Kong SAR, China
    Ann Surg 246:728-33. 2007
    Laparoscopic colectomy has been proved to be both technically and oncologically feasible...
  95. ncbi Visceral obesity predicts surgical outcomes after laparoscopic colectomy for sigmoid colon cancer
    Shingo Tsujinaka
    Department of Surgery, Jichi Medical University Saitama Medical Center, Saitama, Japan
    Dis Colon Rectum 51:1757-65; discussion 1765-7. 2008
    This study was designed to assess whether visceral obesity is a more useful predictor of surgical outcomes compared with body mass index after laparoscopic colectomy.
  96. ncbi Postoperative ileus: it costs more than you expect
    Theodor Asgeirsson
    Department of Surgery, Michigan State University, Grand Rapids, MI, USA
    J Am Coll Surg 210:228-31. 2010
    The clinical impact of postoperative ileus (POI) after colectomy is difficult to quantify financially because of administrative coding limitations...
  97. pmc Colorectal cancer outcomes, recurrence, and complications in persons with and without diabetes mellitus: a systematic review and meta-analysis
    Kelly B Stein
    Division of General Internal Medicine, Johns Hopkins School of Medicine, Baltimore, MD 21205, USA
    Dig Dis Sci 55:1839-51. 2010
    ....
  98. ncbi Colectomy rate comparison after treatment of ulcerative colitis with placebo or infliximab
    William J Sandborn
    Division of Gastroenterology and Hepatology, Mayo Clinic, Rochester, Minnesota, USA
    Gastroenterology 137:1250-60; quiz 1520. 2009
    ..The efficacy of infliximab for treating patients with ulcerative colitis has been established...
  99. ncbi Randomized clinical trial of multimodal optimization of surgical care in patients undergoing major colonic resection
    M Gatt
    Combined Gastroenterology Research Unit, Scarborough General Hospital, Scarborough, UK
    Br J Surg 92:1354-62. 2005
    ..The aim of this trial was to compare multimodal optimization with conventional perioperative management in a consecutive series of patients undergoing a wide range of colorectal procedures...
  100. ncbi Enhanced recovery in colorectal resections: a systematic review and meta-analysis
    C J Walter
    Academic Surgical Unit, The University of Hull, Castle Hill Hospital, Cottingham, Hull, UK
    Colorectal Dis 11:344-53. 2009
    ..The study aimed to produce a comprehensive up-to-date meta-analysis exploring the safety and efficacy of enhanced recovery (ER) programmes after colorectal resection...
  101. ncbi Systematic evaluation of surgical strategies for acute malignant left-sided colonic obstruction
    S Breitenstein
    Department of Visceral and Transplantation Surgery, Zurich, Switzerland
    Br J Surg 94:1451-60. 2007
    ..Surgical strategy for acute colorectal obstruction due to colorectal cancer remains controversial. One-, two- and three-stage surgical procedures, and preoperative stenting of the stenosis as a bridge to surgery, are available...

Research Grants63

  1. Chemoprevention of colitis-associated colon cancer
    E Thompson; Fiscal Year: 2007
    ..inflammation to CAC, will identify the role of PKC(ll and PPAR( in CAC, and may ultimately provide an alternative means of chemoprevention to patients who presently have no alternative to colectomy. [unreadable] [unreadable] [unreadable]
  2. Th2 Cytokines and Signaling in Pediatric Inflammatory Bowel Disease
    Michael J Rosen; Fiscal Year: 2013
    ..This distinction may explain the disease refractoriness of many UC patients and the 20% colectomy rate for pediatric UC...
  3. Fecal Bacteriotherapy for Relapsing Clostridium difficile Infection
    COLLEEN RENEE KELLY; Fiscal Year: 2013
    ..This rise has been accompanied by increasing rates of severe disease resulting in colectomy and/or death...
  4. Curcumin chemoprevention in familial adenomatous polyposis
    Francis M Giardiello; Fiscal Year: 2013
    ..Virtually all affected patients will develop colorectal cancer if prophylactic colectomy is not performed...
  5. MyFAP: A Multimedia Intervention for Adolescents and Young Adults with FAP
    JEFFERY MCLAUGHLIN; Fiscal Year: 2012
    ..screening by endoscopy beginning in their adolescent years, and will need to consider having a prophylactic colectomy by their late teens or early twenties...
  6. The role of stromal APC haploinsufficiency in colorectal tumorigenesis
    JAMES PETER ROBINSON; Fiscal Year: 2013
    ..Prophylactic colectomy is usually performed as a preventative measure...
  7. The Role of the Gut Microbiota in Ulcerative Colitis
    Vincent B Young; Fiscal Year: 2012
    ..We will characterize the gut microbiota in human patients who have undergone total colectomy with the construction of an ileal pouch anal anastomosis for treatment of ulcerative colitis...
  8. Differentiating Ulcerative Colitis and Crohns Colitis Through Proteomic Patterns
    AMOSY EPHREIM M'KOMA; Fiscal Year: 2013
    ..This is called indeterminate colitis (IC). About 90% o IC is diagnosed at the time of colectomy for fulminant colitis and subsequent management critically depends on the correct diagnosis...
  9. Acupuncture to aid post-colectomy recovery in colorectal cancer patients
    Gary Deng; Fiscal Year: 2007
    ..patient blinded intervention trial, colorectal cancer patients undergoing segmental or subtotal colectomy with primary anastomosis will receive acupuncture or sham acupuncture twice daily for 4 days after surgery...
  10. Local Warming: Effects on Wound Infection and Healing
    JoAnne Whitney; Fiscal Year: 2007
    ..Warming incisions immediately after surgery and intermittently for two days after gastric bypass or colectomy surgery reduced infection rates, but systematic study of clinical outcomes and potential mechanisms is lacking...
  11. GENETIC LINKAGE BETWEEN UC AND THE HLA CLASS II LOCI
    Richard Duerr; Fiscal Year: 1999
    ..for perinuclear antineutrophil cytoplasmic antibodies, extent of colonic involvement with UC, or need for colectomy because of medically refractory disease in the affected relative pairs with UC; and stratify the linkage ..
  12. Intestinal Microbiota in Diverticular Disease
    Lisa L Strate; Fiscal Year: 2013
    ..However, few risk factors have been identified, and no preventative strategies exist short of segmental colectomy. The role of human intestinal microbiota in disease is increasingly being recognized...
  13. Cost and Quality of Cancer Surgery
    Vivian Ho; Fiscal Year: 2012
    ..exists for complex operations such as pancreatic resection, and for more commonly performed procedures such as colectomy. We recently published a study that found that relative to low-volume surgeons, treatment by high-volume ..
  14. Predicting Clostridium difficile infection: Preoperative risk factors
    GRETA L KRAPOHL; Fiscal Year: 2011
    ..a retrospective, cohort design, we will determine the preoperative risk factors of CDI from over two years of colectomy surgical patients data (1800 patients) from the 23 hospitals enrolled in the Michigan Surgical Quality ..
  15. Chemoprevention of Duodenal Polyps in FAP
    James DiSario; Fiscal Year: 2003
    ..polyps and on adenoma and mucosal apoptosis assays in Familial Adenomatous Polyposis (FAP) patients who have had colectomy or Attenuated Adenomatous Polyposis Coli (AAPC) patients whom may or may not have undergone colectomy...
  16. PHASE III TRIAL--LAPAROSCOPIC COLECTOMY FOR COLON CANCER
    Heidi Nelson; Fiscal Year: 2000
    ..Although oncologic results from open colectomy are well-established, these traditional resective and staging techniques are challenged by the introduction of ..
  17. ROLE OF PROXIMAL COLONIC LYMPHOID TISSUE IN IMMUNITY
    Greg Perry; Fiscal Year: 1991
    ..PCLT in irradiated individuals, 7) examine the effects of lymphokines on PCLT, and 8) determine whether proximal colectomy might cure autoimmune disease in animals whose autoimmune disease is associated with high levels of Ly-1 B cells...
  18. Prophylactic colectomy intentions in HNPCC patients
    Karen Hurley; Fiscal Year: 2005
    ..risk of developing colorectal cancer and a 40 to 50 percent chance of a metachronous tumor after partial colectomy for the disease...
  19. The Role of the Gut Microbiota in Ulcerative Colitis
    Vincent Young; Fiscal Year: 2009
    ..We will characterize the gut microbiota in human patients who have undergone total colectomy with the construction of an ileal pouch anal anastomosis for treatment of ulcerative colitis...
  20. SEARCHING FOR EVIDENCE OF INFECTION IN CROHN'S DISEASE
    Zhiheng Pei; Fiscal Year: 2001
    ..To identify a viral agent, a serosal window will be opened on fresh ileectomy/colectomy specimens resected from CD patients, and a biopsy of the muscularis will be obtained through the window...
  21. NEOPLASTIC PROGRESSION IN ULCERATIVE COLITIS
    Frederic Waldman; Fiscal Year: 1999
    ..genomic hybridization (CGH) and fluorescence in situ hybridization (FISH), to archival UC-related cancer colectomy specimens to define the earliest and most important genetic changes in UC-related neoplasia...
  22. MARKERS FOR STEM CELL-LIKE COLONIC CRYPT BASE CELLS
    Bruce Boman; Fiscal Year: 2004
    ..Tissue samples from surgical colectomy specimens will be collected, colonic crypts purified, and microarray analysis done to characterize SCE ..
  23. CANCER SCREENING COMPLIANCE IN HEREDITARY COLON CANCER
    Sapna Syngal; Fiscal Year: 2005
    ..Intensive surveillance beginning at age 25 and/or prophylactic colectomy and annual endometrial cancer screening are recommended in at-risk family members...
  24. Preventing Neoplastic Progression in Ulcerative Colitis
    Thomas Ullman; Fiscal Year: 2009
    ..no published report demonstrates a mortality benefit for surveillance, but the lack of appeal for prophylactic colectomy or waiting for a symptomatic cancer to arise has led to near universal acceptance of this unproven practice...
  25. PHASE II CLINICAL TRIAL OF CELECOXIB IN PERSONS WITH GE
    Patrick Lynch; Fiscal Year: 2000
    ..Although the standard of care has long been considered to be colectomy at diagnosis, practitioners and patients have been increasingly willing to undergo surveillance until there is ..
  26. Disparities in Surgical Outcomes and Hospital Volume
    Leslie Boxer; Fiscal Year: 2005
    ..surgical care procedures (pancreatectomy for pancreatic cancer, esophageal resection for esophageal cancer, colectomy for colon cancer and lung resection for lung cancer) done at both high and low volume hospitals and examine the ..
  27. PHENOTYPIC AND PSYCHOSOCIAL STUDY OF THE L1307K MUTATION
    Henry Lynch; Fiscal Year: 2004
    ....
  28. ALPHA 2 ADRENERGIC CONTROL IN IRRITABLE BOWEL SYNDROME
    Michael Camilleri; Fiscal Year: 2008
    ..Significance: This project will characterize pharmacogenetic mechanisms determining the response to clonidine through studies of candidate genes that control alpha2-adrenoreceptor function and norepinephrine transport in IBS. ..
  29. IMURAN Dose Ranging Study in Crohn's Disease
    BRUCE SANDS; Fiscal Year: 2005
    ..Abstract Not Provided ..
  30. ALPHA-2 ADRENERGIC CONTROL OF COLONIC FUNCTION IN IBS
    Michael Camilleri; Fiscal Year: 2007
    ..abstract_text> ..
  31. OSCCAR: A Novel, Population-based Prospective Inception Cohort of Inflammatory Bo
    BRUCE SANDS; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  32. INCREASING COLORECTAL CANCER SCREENING
    Randall Burt; Fiscal Year: 2005
    ..abstract_text> ..
  33. Racial Disparities in Inflammatory Bowel Disease
    GEOFFREY NGUYEN; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  34. IMMUNOMODULATION IN INFLAMMATORY BOWEL DISEASE
    BRUCE SANDS; Fiscal Year: 2004
    ..The principal investigator seeks to become an independent clinical investigator by completing the didactic and scientific portions of this proposal. ..
  35. Clinical Approaches to Ileal Pouch Dysfunction
    Bo Shen; Fiscal Year: 2005
    ..The AIMS of study are to 1) investigate visceral hypersensitivity using barostat examination of the pouch; 2) conduct a randomized, placebo-controlled clinical trial evaluating the use of amitriptyline in IPS. ..
  36. Cannabinoid Mechanisms in Human Gastrointestinal Motor and Sensory Functions
    MICHAEL L CAMILLERI; Fiscal Year: 2010
    ..These actions may be relevant to develop new treatments for IBS. The studies will also provide further understanding of the potential of medications like medical marijuana on stomach function that may be relevant to appetite control. ..
  37. HIGH RISK FAMILIAL COLON CANCER- GENETICS AND PHENOTYPE
    Randall Burt; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  38. TFF3 GENE EXPRESSION IN METASTATIC COLON CANCER
    Steven Itzkowitz; Fiscal Year: 2001
    ..The use of the TFF3 gene to drive expression of suicide genes offers a novel approach which should result in more targetted, safer gene therapy for metastatic colon cancer. ..
  39. COST EFFECTIVENESS OF GENETIC SCREENING FOR COLON CANCER
    Scott Ramsey; Fiscal Year: 2002
    ....
  40. Lung/Colon Cancer Outcomes--Cancer Research Network
    Jane Weeks; Fiscal Year: 2008
    ..abstract_text> ..
  41. BENEFITS OF REGIONALIZING SURGERY FOR MEDICARE PATIENTS
    John Birkmeyer; Fiscal Year: 2002
    ..The investigators will then estimate the change in mortality, by assuming that the patient will acquire the average predicted mortality for a similar patient at the larger volume hospital. ..
  42. Structure, Process and Outcomes in Cancer Surgery
    John D Birkmeyer; Fiscal Year: 2010
    ..We will then identify the resources and processes of care that account for differences in hospital outcomes, with the ultimate goal of identifying best practices and improving care in all settings. ..
  43. CLINICAL AND BIOLOGICAL BASIS OF 18F-FDG PET IN CANCER
    Yuman Fong; Fiscal Year: 2001
    ..abstract_text> ..
  44. TRIAL TO REDUCE DELIRIUM IN AGED POST ACUTE PATIENTS
    Edward Marcantonio; Fiscal Year: 2004
    ..If the DAP is successful in reducing delirium and improving functional recovery, our findings will serve as a model of a targeted approach to improve the care of elders in the post-acute setting. ..
  45. MEDICAL OUTCOMES IN THE PRICING OF HOSPITAL PROCEDURES
    Avi Dor; Fiscal Year: 2001
    ..However, based on 1994 frequencies, final samples are expected to range from 900 to 2,400 per year, depending on the procedure and elective/emergency setting. ..
  46. INJURY TO LIVER SINUSOIDAL ENDOTHELIAL CELLS
    Steven Strasberg; Fiscal Year: 2003
    ..A potentially beneficial improvements in preservation solutions are identified they will be tested in whole isolated livers and by transplantation in the rat. ..
  47. Epidemiology of Marginal Zone Lymphoma
    Lisa Herrinton; Fiscal Year: 2003
    ..abstract_text> ..
  48. Intl Pediatric Inflammatory Bowel Disease (IBD) Meeting
    Claudio Fiocchi; Fiscal Year: 2003
    ..abstract_text> ..
  49. Vein wall remodeling after DVT is matrix metalloproteinase dependent
    Peter Henke; Fiscal Year: 2009
    ..This proposal will provide important mechanistic insight into the pathophysiology of post-phelbitic syndrome with real potential translation to decreasing the morbidity from this under-acknowledged disease. ..
  50. Influence of Tumor Immunogenicity to Immunotherapy
    Jeffrey Norton; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  51. Thrombus resolution is CXC chemokine dependent
    Peter Henke; Fiscal Year: 2006
    ..abstract_text> ..
  52. Genetic Analysis of DAF-18/PTEN Signaling in C.elegans
    PATRICK HU; Fiscal Year: 2006
    ..elegans, the well- annotated and complete genome sequence, and the recent adaptation of RNAi to h i gh-throughput analysis, this approach should greatly accelerate our understanding of DAF-18/PTEN signaling. ..
  53. A Genetic Screening Policy Model for Colorectal Cancer
    Scott Ramsey; Fiscal Year: 2006
    ..The model will incorporate QOL information from Aim 2, along with family history, clinical, and screening information from the Seattle CFR. ..
  54. CLOTRIMAZOLE ENEMAS FOR POUCHITIS IN CHILDREN AND ADULTS
    PAUL RUFO; Fiscal Year: 2005
    ..Abstract Not Provided ..
  55. Neoadjuvant Cytokine Immunotherapy by PLA Microspheres
    Michael Sabel; Fiscal Year: 2007
    ..I will pursue this area of investigation as a full-time faculty member, with full commitment from the Department of General Surgery and the Division of Surgical Oncology at the University of Michigan Medical Center. ..
  56. Donepezil-enhanced management of delirium in aged hip fracture patients
    Edward Marcantonio; Fiscal Year: 2007
    ..This study is the first in the PI's long-term goal to better understand the pathophysiological mechanisms of delirium and to develop and test therapies targeted to address these mechanisms. [unreadable] [unreadable] [unreadable]..
  57. Caregiver-based Intervention for Persistent Delirium
    Edward Marcantonio; Fiscal Year: 2007
    ..If promising, our findings will serve as pilot data for a definitive trial to test this novel strategy to improve the health of a vulnerable population of elders and their caregivers. [unreadable] [unreadable] [unreadable]..
  58. Career Development in Cancer Prevention Research at FCCC
    Paul Engstrom; Fiscal Year: 2007
    ..An Education Advisory Committee will monitor recruitment procedures, provide oversite of the program, certify completion of candidate training, and evaluate effectiveness of the program. ..
  59. Mechanisms of Bone Loss in Pediatric Crohn Disease
    Francisco Sylvester; Fiscal Year: 2008
    ..abstract_text> ..
  60. Liver Regeneration in Man--Effects or Adjuvant Therapy
    Yuman Fong; Fiscal Year: 2005
    ....
  61. SACRAL CREST CELLS AND ENTERIC NEURODEVELOPMENT
    Raj Kapur; Fiscal Year: 2005
    ..The results of this study will further our understanding of normal enteric neurodevelopment and congenital disorders of intestinal motility. ..