Genomes and Genes
coronary artery bypass
Summary: Surgical therapy of ischemic coronary artery disease achieved by grafting a section of saphenous vein, internal mammary artery, or other substitute between the aorta and the obstructed coronary artery distal to the obstructive lesion.
Publications295 found, 100 shown here
- Remote ischemic preconditioning in human coronary artery bypass surgery: from promise to disappointment?Ishtiaq A Rahman
Department of Cardiothoracic Surgery, University Hospital Birmingham NHS Trust, Edgbaston, Birmingham, UK
Circulation 122:S53-9. 2010..We assessed whether remote ischemic preconditioning (RIPC) improves myocardial, renal, and lung protection after on-pump coronary surgery...
- Cardioprotective and prognostic effects of remote ischaemic preconditioning in patients undergoing coronary artery bypass surgery: a single-centre randomised, double-blind, controlled trialMatthias Thielmann
Department of Thoracic and Cardiovascular Surgery, Universitatsklinikum Essen, Essen, Germany
Lancet 382:597-604. 2013Remote ischaemic preconditioning has been associated with reduced risk of myocardial injury after coronary artery bypass graft (CABG) surgery. We investigated the safety and efficacy of this procedure.
- Percutaneous coronary intervention versus coronary-artery bypass grafting for severe coronary artery diseasePatrick W Serruys
Erasmus University Medical Center Rotterdam, Rotterdam, The Netherlands
N Engl J Med 360:961-72. 2009..Our trial compared PCI and CABG for treating patients with previously untreated three-vessel or left main coronary artery disease (or both)...
- Coronary revascularization trends in the United States, 2001-2008Andrew J Epstein
Department of Veterans Affairs Center for Health Equity Research and Promotion, Philadelphia, Pennsylvania, USA
JAMA 305:1769-76. 2011..It is uncertain how new revascularization technologies, new clinical evidence from trials, and updated clinical guidelines have influenced the volume and distribution of coronary revascularizations over the past decade...
- Effect of remote ischaemic preconditioning on myocardial injury in patients undergoing coronary artery bypass graft surgery: a randomised controlled trialDerek J Hausenloy
The Hatter Cardiovascular Institute, University College London Hospital, London, UK
Lancet 370:575-9. 2007..organ protects remote organs from a sustained episode of ischaemia, is beneficial for patients undergoing coronary artery bypass graft surgery is unknown...
- Strategies for multivessel revascularization in patients with diabetesMichael E Farkouh
Mount Sinai School of Medicine, New York, NY 10029, USA
N Engl J Med 367:2375-84. 2012..We sought to discover whether aggressive medical therapy and the use of drug-eluting stents could alter the revascularization approach for patients with diabetes and multivessel coronary artery disease...
- N-3 Fatty acids for the prevention of atrial fibrillation after coronary artery bypass surgery: a randomized, controlled trialLeonardo Calo
Department of Cardiac Diseases, San Filippo Neri Hospital, Rome, Italy
J Am Coll Cardiol 45:1723-8. 2005..of this study was to assess the efficacy of preoperative and postoperative treatment with n-3 polyunsaturated fatty acids (PUFAs) in preventing the occurrence of atrial fibrillation (AF) after coronary artery bypass graft surgery (CABG).
- Transfusion in coronary artery bypass grafting is associated with reduced long-term survivalColleen Gorman Koch
Department of Cardiothoracic Anesthesia, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
Ann Thorac Surg 81:1650-7. 2006..we examined the influence of PRBC transfusion and component therapy on long-term survival after isolated coronary artery bypass grafting after controlling for the effect of demographics, comorbidities, operative factors, and the early ..
- Omega-3 fatty acid supplementation does not reduce risk of atrial fibrillation after coronary artery bypass surgery: a randomized, double-blind, placebo-controlled clinical trialPalaniappan Saravanan
University of Manchester, Manchester, United Kingdom
Circ Arrhythm Electrophysiol 3:46-53. 2010..Omega-3 polyunsaturated fatty acids (n-3 PUFA) have been reported to reduce the risk of sudden cardiac death presumed to be due to fatal ventricular arrhythmias, but their effect on atrial arrhythmias is unclear...
- Use of cardiac rehabilitation by Medicare beneficiaries after myocardial infarction or coronary bypass surgeryJose A Suaya
Schneider Institutes for Health Policy, Heller School MS 035, Brandeis University, Waltham, MA 02454 9110, USA
Circulation 116:1653-62. 2007..Cardiac rehabilitation (CR) is effective in prolonging survival and reducing disability in patients with coronary heart disease. However, national use patterns and predictors of CR use have not been evaluated thoroughly...
- Off-pump or on-pump coronary-artery bypass grafting at 30 daysAndre Lamy
Population Health Research Institute, Hamilton Health Sciences, McMaster University, Hamilton, ON, Canada
N Engl J Med 366:1489-97. 2012..The relative benefits and risks of performing coronary-artery bypass grafting (CABG) with a beating-heart technique (off-pump CABG), as compared with cardiopulmonary bypass (on-pump CABG), are not clearly established...
- Protection by remote ischemic preconditioning during coronary artery bypass graft surgery with isoflurane but not propofol - a clinical trialE Kottenberg
Klinik für Anästhesiologie und Intensivmedizin, Universitat Duisburg Essen, Universitatsklinikum Essen, Germany
Acta Anaesthesiol Scand 56:30-8. 2012..Specifically, we hypothesized that RIPC during isoflurane anesthesia attenuates myocardial injury in patients undergoing coronary artery bypass graft (CABG) surgery, and that effects may be different during propofol anesthesia.
- Impact of preoperative anemia on outcome in patients undergoing coronary artery bypass graft surgeryAlexander Kulier
Department of Anesthesiology and Intensive Care Medicine, Medical University of Graz, Graz, Austri
Circulation 116:471-9. 2007..Thus, we determined the effects of low preoperative hemoglobin and comorbidities on postoperative adverse outcomes in patients with coronary artery bypass graft in a large comprehensive multicenter study.
- Remote ischemic preconditioning reduces myocardial injury after coronary artery bypass surgery with crystalloid cardioplegic arrestMatthias Thielmann
Department of Thoracic and Cardiovascular Surgery, West German Heart Center Essen, University Hospital Essen, Germany
Basic Res Cardiol 105:657-64. 2010..RIPC) with transient upper limb ischemia reduces myocardial injury in patients undergoing on-pump coronary artery bypass grafting (CABG) with cross-clamp fibrillation or blood cardioplegia for myocardial protection...
- Improved survival with radial artery versus vein conduits in coronary bypass surgery with left internal thoracic artery to left anterior descending artery graftingAnoar Zacharias
Division of Cardiovascular Surgery, St Vincent Mercy Medical Center, Toledo, Ohio 43608, USA
Circulation 109:1489-96. 2004..This grafting also led to increased use of other arterial conduits, of which the radial artery is most popular. Whether radial grafting improves survival beyond that achieved by LITA-LAD alone is not known...
- A comparison of on-pump and off-pump coronary bypass surgery in low-risk patientsHendrik M Nathoe
Department of Cardiology, University Medical Center Utrecht, Utrecht, The Netherlands
N Engl J Med 348:394-402. 2003....
- Effect of remote ischemic preconditioning on clinical outcomes in patients undergoing coronary artery bypass graft surgery (ERICCA): rationale and study design of a multi-centre randomized double-blinded controlled clinical trialDerek J Hausenloy
The Hatter Cardiovascular Institute, University College London, London, UK
Clin Res Cardiol 101:339-48. 2012..Novel cardioprotective strategies are required to improve clinical outcomes in high risk patients undergoing coronary artery bypass graft (CABG) ± valve surgery...
- Reappraisal of a 20-year experience with the radial artery as a conduit for coronary bypass graftingPaul Achouh
Department of Cardiovascular Surgery, Hôpital Georges Pompidou, Paris, France
Eur J Cardiothorac Surg 41:87-92. 2012..This study aimed at evaluating the clinical and angiographic results of the radial artery (RA) used as a coronary bypass graft over 20 years...
- The impact of deep sternal wound infection on long-term survival after coronary artery bypass graftingIoannis K Toumpoulis
St Luke s Roosevelt Hospital Center at Columbia University, 45 East Eighty Ninth St, New York, NY 10128, USA
Chest 127:464-71. 2005To identify the impact of deep sternal wound infection (DSWI) on long-term survival after coronary artery bypass grafting (CABG).
- An alternative scoring system to predict risk for surgical site infection complicating coronary artery bypass graft surgeryN Deborah Friedman
Victorian Hospital Acquired Infection Surveillance System, Melbourne, Victoria, Australia
Infect Control Hosp Epidemiol 28:1162-8. 2007To analyze the risk factors for surgical site infection (SSI) complicating coronary artery bypass graft (CABG) surgery and to create an alternative SSI risk score based on the results of multivariate analysis.
- Presurgical depression predicts medical morbidity 6 months after coronary artery bypass graft surgeryMatthew M Burg
VA Connecticut Healthcare System, West Haven Campus, West Haven, CT 06516, USA
Psychosom Med 65:111-8. 2003..to poor medical prognosis in patients with coronary artery disease and to diminished quality of life after coronary artery bypass graft surgery (CABG)...
- Coronary artery bypass graft surgery versus percutaneous coronary intervention in patients with three-vessel disease and left main coronary disease: 5-year follow-up of the randomised, clinical SYNTAX trialFriedrich W Mohr
Herzzentrum Universität Leipzig, Leipzig, Germany
Lancet 381:629-38. 2013We report the 5-year results of the SYNTAX trial, which compared coronary artery bypass graft surgery (CABG) with percutaneous coronary intervention (PCI) for the treatment of patients with left main coronary disease or three-vessel ..
- Acute kidney injury following coronary artery bypass surgery and long-term risk of heart failureDaniel Olsson
Department of Emergency Medicine, Karolinska University Hospital, Stockholm, Sweden
Circ Heart Fail 6:83-90. 2013Acute kidney injury (AKI) after coronary artery bypass grafting (CABG) is common and increases the risk of postoperative complications and mortality...
- The influence of propofol or desflurane on postoperative cognitive dysfunction in patients undergoing coronary artery bypass surgeryC F Royse
Anaesthesia and Pain Management Unit, Department of Pharmacology, University of Melbourne, Carlton, Victoria
Anaesthesia 66:455-64. 2011..on the incidence of postoperative cognitive dysfunction in a randomised trial of 180 patients undergoing coronary artery bypass surgery...
- Preoperative proteinuria predicts adverse renal outcomes after coronary artery bypass graftingTao Min Huang
Division of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, 7 Chung Shan South Road, Zhong Zheng District, Taipei 100, Taiwan
J Am Soc Nephrol 22:156-63. 2011..Here, we performed a secondary analysis of a prospectively enrolled cohort of adult patients undergoing coronary artery bypass grafting (CABG) at a medical center and its two affiliate hospitals between 2003 and 2007...
- Neutrophil gelatinase associated lipocalin as a biomarker for acute kidney injury in patients undergoing coronary artery bypass grafting with cardiopulmonary bypassA Prabhu
Department of Biochemistry, MMM Academy of Medical Sciences, Mogapair, Chennai 600037, India
Ann Vasc Surg 24:525-31. 2010..plasma neutrophil gelatinase associated lipocalin (NGAL) levels as a predictor of renal injury in patients undergoing coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB) along with markers of oxidative stress.
- Usefulness of neutrophil/lymphocyte ratio as predictor of new-onset atrial fibrillation after coronary artery bypass graftingPatrick H Gibson
Department of Cardiology, University of Aberdeen and Aberdeen Royal Infirmary, Aberdeen, United Kingdom
Am J Cardiol 105:186-91. 2010..the relation between the N/L ratio and postoperative atrial fibrillation (AF) in patients undergoing coronary artery bypass grafting...
- Plasma n-3 and n-6 fatty acids and the incidence of atrial fibrillation following coronary artery bypass graft surgeryGudrun V Skuladottir
Department of Physiology, School of Health Sciences, University of Iceland, Reykjavik, Iceland
Eur J Clin Invest 41:995-1003. 2011..We examined the association between n-3 LC-PUFA and n-6 LC-PUFA in plasma phospholipids (PL) and POAF in patients undergoing coronary artery bypass grafting (CABG).
- Meta-analysis of randomised trials comparing the effectiveness of miniaturised versus conventional cardiopulmonary bypass in adult cardiac surgeryF Biancari
Division of Cardio Thoracic and Vascular Surgery, Department of Surgery, Oulu University Hospital, Oulu, Finland
Heart 95:964-9. 2009..The aim of this meta-analysis is to summarise the results of prospective, randomised studies comparing miniaturised (Mini-CPB) versus conventional cardiopulmonary bypass (C-CPB)...
- Results of percutaneous coronary intervention of the unprotected left main coronary artery in 143 patients and comparison of 30-day mortality to results of coronary artery bypass graftingChristophe Dubois
Department of Cardiology, University Hospitals Leuven, Leuven, Belgium
Am J Cardiol 101:75-81. 2008..Mortality remains high in very high-risk patients unsuitable for surgery. However, in selected indications, PCI of the LMCA can offer an alternative to surgery, especially when using drug-eluting stents...
- The clinical and economic impact of deep chest surgical site infections following coronary artery bypass graft surgeryC S Hollenbeak
Pennsylvania State College of Medicine, Hershey 17033, USA
Chest 118:397-402. 2000To examine how deep chest surgical site infections following coronary artery bypass graft (CABG) surgery impact hospital inpatient length of stay (LOS), costs, and mortality.
- Cellular, molecular and immunological mechanisms in the pathophysiology of vein graft intimal hyperplasiaAmit K Mitra
Department of Biomedical Sciences, Creighton University School of Medicine, Omaha, NE 68178, USA
Immunol Cell Biol 84:115-24. 2006..Invasive techniques such as coronary artery bypass grafting are used to alleviate the sequelae of arterial occlusion...
- Transit-time flow measurement is essential in coronary artery bypass graftingDerek K H Leong
Faculty of Medicine, National University of Singapore, Singapore, Singapore
Ann Thorac Surg 79:854-7; discussion 857-8. 2005Patent bypass grafts are fundamental to successful coronary artery bypass grafting. Intraoperative flow measurement through newly constructed grafts is a test of patency...
- ACC/AHA 2004 guideline update for coronary artery bypass graft surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1999 Guidelines for Coronary Artery Bypass Graft SKim A Eagle
Circulation 110:e340-437. 2004
- Effect of arterial revascularisation on survival: a systematic review of studies comparing bilateral and single internal mammary arteriesD P Taggart
Oxford Heart Centre, John Radcliffe Hospital, OX3 9DU, Oxford, UK
Lancet 358:870-5. 2001b>Coronary artery bypass grafting (CABG) is the commonest major operation in most developed countries...
- Aerobic interval training versus continuous moderate exercise after coronary artery bypass surgery: a randomized study of cardiovascular effects and quality of lifeTrine T Moholdt
Department of Circulation and Medical Imaging, Norwegian University of Science and Technology NTNU, Trondheim, Norway
Am Heart J 158:1031-7. 2009..We compared the effects of aerobic interval training (AIT) versus moderate continuous training (MCT) on Vo(2peak) and quality of life after coronary artery bypass grafting (CABG).
- Age-dependent depression in circulating endothelial progenitor cells in patients undergoing coronary artery bypass graftingRobert J Scheubel
Department of Cardiothoracic Surgery, and Institute of Epidemiology, Biostatistics and Informatics, Martin Luther University Halle Wittenberg, Halle Saale, Germany
J Am Coll Cardiol 42:2073-80. 2003The effect of patient age on circulating endothelial progenitor cells (EPCs) and their mobilization during coronary artery bypass grafting (CABG) was assessed.
- Efficacy and safety of edifoligide, an E2F transcription factor decoy, for prevention of vein graft failure following coronary artery bypass graft surgery: PREVENT IV: a randomized controlled trialJohn H Alexander
Duke University Medical Center, Duke Clinical Research Institute, Durham, NC 27715, USA
JAMA 294:2446-54. 2005b>Coronary artery bypass graft (CABG) surgery with autologous vein grafting is commonly performed. Progressive neointimal hyperplasia, however, contributes to considerable vein graft failure...
- Long-term patency of saphenous vein and left internal mammary artery grafts after coronary artery bypass surgery: results from a Department of Veterans Affairs Cooperative StudySteven Goldman
Southern Arizona VA Health Care System and the University of Arizona Sarver Heart Center, Tucson, Arizona, USA
J Am Coll Cardiol 44:2149-56. 2004..This study defined long-term patency of saphenous vein grafts (SVG) and internal mammary artery (IMA) grafts...
- Beneficial effects of intravenously administered N-3 fatty acids for the prevention of atrial fibrillation after coronary artery bypass surgery: a prospective randomized studyM C Heidt
Cardiology, University Clinic Giessen, 35392 Giessen, Germany
Thorac Cardiovasc Surg 57:276-80. 2009Atrial fibrillation (AF) is a common complication after coronary artery bypass grafting operation (CABG). Experimental data have shown antiarrhythmic effects of n-3 polyunsaturated fatty acids (PUFA) on myocardial cells...
- Morbid results of prolonged intubation after coronary artery bypass surgeryA J Cohen
Department of Cardiothoracic Surgery, Wolfson Medical Center, Holon affiliated with Sackler Faculty of Medicine, Tel Aviv University, Ramat Aviv, Israel
Chest 118:1724-31. 2000This study evaluated the morbid results of prolonged intubation after coronary artery bypass grafting (CABG).
- Effects of storage time of red blood cell transfusions on the prognosis of coronary artery bypass graft patientsLeo van de Watering
Department of Immunohematology and Blood Transfusion, Leiden University Medical Center, Leiden, The Netherlands
Transfusion 46:1712-8. 2006..The aim in this study was to investigate the possible role of the storage time of RBC transfusions on the outcome of coronary artery bypass graft (CABG) surgery patients.
- Intramyocardial delivery of CD133+ bone marrow cells and coronary artery bypass grafting for chronic ischemic heart disease: safety and efficacy studiesChristof Stamm
Department of Cardiac Surgery, University of Rostock, Rostock, Germany
J Thorac Cardiovasc Surg 133:717-25. 2007..assessed the feasibility and safety of intramyocardial CD133+ bone marrow cell injection together with coronary artery bypass grafting (CABG)...
- Remote ischaemic preconditioning in coronary artery bypass surgery: a meta-analysisFabrizio D'Ascenzo
Division of Cardiology, University of Turin, Turin, Italy
Heart 98:1267-71. 2012Randomised trials exploring remote ischaemic preconditioning (RIPC) in patients undergoing coronary artery bypass graft (CABG) surgery have yielded conflicting data regarding potential cardiovascular and renal protection, and are ..
- Do off-pump techniques reduce the incidence of postoperative atrial fibrillation in elderly patients undergoing coronary artery bypass grafting?Thanos Athanasiou
The National Heart and Lung Institute, Imperial College of Science, Technology and Medicine, Department of Cardiothoracic Surgery, St Mary s Hospital and Royal Brompton Hospital, London, United Kingdom
Ann Thorac Surg 77:1567-74. 2004Atrial fibrillation is the most common postoperative complication in patients undergoing coronary artery bypass grafting (CABG) with advancing age having been shown to have a significant association with its incidence...
- Storage time of allogeneic red blood cells is associated with risk of severe postoperative infection after coronary artery bypass graftingJan Jesper Andreasen
Department of Cardiothoracic Surgery, Center for Cardiovascular Research, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark
Eur J Cardiothorac Surg 39:329-34. 2011..We therefore examined the association between the age of transfused RBCs and development of severe postoperative infection following coronary artery bypass grafting (CABG) in a large population-based cohort study.
- Delirium after coronary artery bypass graft surgery and late mortalityRebecca F Gottesman
Department of Neurology, Johns Hopkins University, 600 N Wolfe Street, Baltimore, MD 21287, USA
Ann Neurol 67:338-44. 2010..The primary goal of this study was to determine whether patients with delirium after coronary artery bypass graft (CABG) surgery have higher long-term out-of-hospital mortality when compared with CABG patients ..
- Lack of protective role of HDL-C in patients with coronary artery disease undergoing elective coronary artery bypass graftingEmiliano Angeloni
Department of Cardiac Surgery, University of Rome Sapienza, Ospedale Sant Andrea, Rome, Italy
Eur Heart J 34:3557-62. 2013..In the present study, we hypothesize that HDL-C may lose their protective role in the secondary prevention of coronary artery disease (CAD)...
- Measurement of post-operative cognitive dysfunction after cardiac surgery: a systematic reviewJ L Rudolph
Geriatric Research Education and Clinical Center, VA Boston Healthcare System, Division of Aging, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02130, USA
Acta Anaesthesiol Scand 54:663-77. 2010..There is marked variability in the measurement and definition of POCD. This heterogeneity may impede progress by reducing the ability to compare studies on the causes and treatment of POCD...
- Impact of off-pump coronary artery bypass surgery on systemic inflammation: current best available evidenceShahzad G Raja
Department of Cardiac Surgery, Western Infirmary Glasgow, Glasgow, United Kingdom
J Card Surg 22:445-55. 2007The systemic inflammatory response after coronary artery bypass grafting using cardiopulmonary bypass (CPB) contributes substantially to postoperative organ dysfunction and coagulation disorders...
- Six-year follow-up of a randomised controlled trial examining hospital versus home-based exercise training after coronary artery bypass graft surgeryKelly M Smith
Department of Medicine, University of Illinois College of Medicine at Chicago, Section of Health Promotion Research, Chicago, Illinois, USA
Heart 97:1169-74. 2011..To compare the long-term effectiveness of hospital versus telephone-monitored home-based exercise training during cardiac rehabilitation (CR) on exercise capacity and habitual physical activity...
- Hypoxaemia after cardiac surgery: clinical application of a model of pulmonary gas exchangeS Kjaergaard
Aalborg Hospital, Department of Anaesthesiology, Aalborg, Denmark
Eur J Anaesthesiol 21:296-301. 2004..Ventilation/perfusion mismatch is quantified by deltaPO2, which is the drop in oxygen pressure from alveoli to lung capillaries. Shunt and deltaPO2 were used to describe changes in oxygenation after coronary artery bypass grafting.
- Effect of duration of red blood cell storage on early and late mortality after coronary artery bypass graftingAlbert H M van Straten
Department of Cardio Thoracic Surgery, Catharina Hospital, Eindhoven, The Netherlands
J Thorac Cardiovasc Surg 141:231-7. 2011..We tested the hypothesis that longer storage of transfused red blood cells increases the risk of early and late mortality in patients who undergo coronary artery bypass grafting.
- Induced remote ischemic pre-conditioning on ischemia-reperfusion injury in patients undergoing coronary artery bypassNasir Ali
Department of Cardiac Surgery, Armed Forces Institute of Cardiology, National Institute of Heart Diseases, Rawalpindi, Pakistan
J Coll Physicians Surg Pak 20:427-31. 2010To determine the role of remote ischemic pre-conditioning (rIPC) on myocardium, against ischemia reperfusion injury in patients undergoing coronary artery bypass graft (CABG) surgery by measuring CKMB levels.
- Cardiac surgery in Germany during 2011: a report on behalf of the German Society for Thoracic and Cardiovascular SurgeryAnne Kathrin Funkat
Department of Cardiac Surgery, Herzzentrum, University of Leipzig, Leipzig, Germany
Thorac Cardiovasc Surg 60:371-82. 2012..4% in 2010. Hospital mortality in 41,976 isolated coronary artery bypass graft procedures (14.7% off-pump) was 2.9%...
- Predictors of atrial fibrillation following coronary artery bypass surgeryMarijana Tadic
Clinical Centre of Serbia, Clinic for Cardiology, Belgrade, Serbia
Med Sci Monit 17:CR48-55. 2011New-onset atrial fibrillation is the most common form of rhythm disturbance following coronary artery bypass grafting surgery (CABG). It is still unclear which factors have a significant impact on its occurrence after this procedure...
- Psychological risk factors for increased post-operative length of hospital stay following coronary artery bypass graft surgeryMelissa Oxlad
School of Psychology, Flinders University, Adelaide, South Australia, Australia
J Behav Med 29:179-90. 2006To date, researchers have examined the role of psychological factors in longer-term adaptation to coronary artery bypass graft surgery (CABG), but few have investigated the role of such factors in the immediate post-operative period...
- Depression is associated with increased mortality 10 years after coronary artery bypass surgeryIngrid Connerney
Division of Quality and Safety, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
Psychosom Med 72:874-81. 2010To determine if depression is independently associated with cardiac and all-cause mortality 10 years after coronary artery bypass graft (CABG) surgery...
- Does location of the second internal thoracic artery graft influence outcome of coronary artery bypass grafting?Joseph F Sabik
Department of Thoracic and Cardiovascular Surgery, Cleveland Clinic, 9500 Euclid Avenue Desk F24, Cleveland, OH 44195, USA
Circulation 118:S210-5. 2008....
- Impact of chronic obstructive pulmonary disease severity on surgical outcomes in patients undergoing non-emergent coronary artery bypass graftingHesham Z Saleh
Department of Cardiothoracic Surgery, Liverpool Heart and Chest Hospital, Liverpool, UK
Eur J Cardiothorac Surg 42:108-13; discussion 113. 2012..Our objective was to analyse the prognostic implication of COPD stages as defined by the Global Initiative for Chronic Obstructive Lung Disease...
- Short-term effects of inspiratory muscle training in coronary artery bypass graft surgery: a randomized controlled trialSema Savci
School of Physical Therapy and Rehabilitation, Dokuz Eylul University, Izmir, Turkey
Scand Cardiovasc J 45:286-93. 2011To investigate the efficiency of inspiratory muscle training (IMT) on postoperative respiratory muscle strength, functional capacity, quality of life, and psychosocial status in patients with coronary artery bypass graft (CABG) surgery.
- Variation in coronary artery bypass grafting, angioplasty, cataract surgery, and hip replacement rates among primary care groups in London: association with population and practice characteristicsAzeem Majeed
School of Public Policy, University College London
J Public Health Med 24:21-6. 2002..However, no studies in the United Kingdom have yet examined the variation in the use of important groups of surgical procedures among primary care groups...
- Prognostic value of chronic obstructive pulmonary disease in coronary artery bypass graftingRafael García Fuster
University General Hospital of Valencia, Valencia 46010, Spain
Eur J Cardiothorac Surg 29:202-9. 2006..Our objective was to analyze its prognostic relevance considering preoperative pulmonary function parameters...
- Off-pump vs. on-pump coronary artery bypass surgery: an updated meta-analysis and meta-regression of randomized trialsJonathan Afilalo
Division of Cardiology, Department of Medicine, SMBD Jewish General Hospital, McGill University, 3755 Cote Ste Catherine, Montreal, Quebec, Canada
Eur Heart J 33:1257-67. 2012The benefits of off-pump coronary artery bypass (OPCAB) continue to be debated, in part due to the fact that pooled effects fail to consider differences in trial and patient characteristics...
- Subclinical changes in serum creatinine and mortality after coronary artery bypass graftingDaniel A Tolpin
Division of Cardiovascular Anesthesiology, The Texas Heart Institute, St Luke s Episcopal Hospital, Houston, TX 77030, USA
J Thorac Cardiovasc Surg 143:682-688.e1. 2012....
- Does preoperative hemoglobin independently predict short-term outcomes after coronary artery bypass graft surgery?Melanie L Bell
Department of Preventive and Social Medicine, University of Otago, Dunedin, New Zealand
Ann Thorac Surg 86:1415-23. 2008The role of preoperative hemoglobin in predicting short-term coronary artery bypass graft (CABG) surgery outcomes has not been well established...
- Location of the second internal mammary artery graft does not influence outcome of coronary artery bypass graftingPaul A Kurlansky
Florida Heart Research Institute, Miami, Florida 33137, USA
Ann Thorac Surg 91:1378-83; discussion 1383-4. 2011Although the use of two internal mammary arteries (IMA) in coronary artery bypass graft surgery has been associated with improved patient survival and clinical status, the optimal use of the second IMA graft remains controversial...
- Compliant model of a coupled sequential coronary arterial bypass graft: effects of vessel wall elasticity and non-Newtonian rheology on blood flow regime and hemodynamic parameters distributionFoad Kabinejadian
School of Mechanical and Aerospace Engineering, Nanyang Technological University, 50 Nanyang Avenue, Singapore 639798, Singapore
Med Eng Phys 34:860-72. 2012..Hence, the inclusion of wall compliance and non-Newtonian rheology in flow simulation of blood vessels can be essential in quantitative and comparative investigations...
- Comparative survival of dialysis patients in the United States after coronary angioplasty, coronary artery stenting, and coronary artery bypass surgery and impact of diabetesCharles A Herzog
Cardiovascular Special Studies Center, United States Renal Data System, Minneapolis, Minn, USA
Circulation 106:2207-11. 2002..The optimal method of coronary revascularization in dialysis patients is controversial. The purpose of this study was to compare the long-term survival of dialysis patients in the United States after PTCA, coronary stenting, or CABG...
- Coronary artery bypass surgery compared with percutaneous coronary interventions for multivessel disease: a collaborative analysis of individual patient data from ten randomised trialsMark A Hlatky
Stanford University School of Medicine, Stanford, CA, USA
Lancet 373:1190-7. 2009b>Coronary artery bypass graft (CABG) and percutaneous coronary intervention (PCI) are alternative treatments for multivessel coronary disease...
- Intramyocardial bone marrow stem cell transplantation during coronary artery bypass surgery: a meta-analysisPeter Donndorf
Department of Cardiac Surgery, University of Rostock, Rostock, Germany
J Thorac Cardiovasc Surg 142:911-20. 2011..clinical studies have suggested that intramyocardial bone marrow stem cell transplantation combined with coronary artery bypass grafting might improve left ventricular function in the setting of chronic ischemic heart disease...
- N-3 polyunsaturated fatty acids reduces post-operative atrial fibrillation incidence in patients undergoing "on-pump" coronary artery bypass graft surgeryMario Sorice
Department of Cardiac Surgery, S Anna e S Sebastiano Hospital, Caserta, Italy Via F Palasciano, 81100 CE, Italy
Monaldi Arch Chest Dis 76:93-8. 2011The aim of this study was to evaluate the efficacy of preoperative and postoperative therapy with n-3 polyunsaturated fatty acids in reducing the incidence of atrial fibrillation after coronary artery bypass graft surgery.
- Aspirin plus clopidogrel versus aspirin alone after coronary artery bypass grafting: the clopidogrel after surgery for coronary artery disease (CASCADE) TrialAlexander Kulik
Lynn Heart and Vascular Institute, University of Ottawa Heart Institute, Ontario, Canada
Circulation 122:2680-7. 2010..in animal studies and therefore may reduce saphenous vein graft (SVG) intimal hyperplasia after coronary artery bypass grafting...
- Meta-analysis of clinical studies comparing coronary artery bypass grafting with percutaneous coronary intervention and drug-eluting stents in patients with unprotected left main coronary artery narrowingsMichael S Lee
Division of Cardiology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA
Am J Cardiol 105:1070-5. 2010The aim of this study was to compare the safety and efficacy of coronary artery bypass grafting (CABG) with percutaneous coronary intervention (PCI) using drug-eluting stents (DES) in patients with unprotected left main coronary artery (..
- A decade of change--risk profiles and outcomes for isolated coronary artery bypass grafting procedures, 1990-1999: a report from the STS National Database Committee and the Duke Clinical Research Institute. Society of Thoracic SurgeonsT Bruce Ferguson
The Society of Thoracic Surgeons National Database Committee, Chicago, Illinois, USA
Ann Thorac Surg 73:480-9; discussion 489-90. 2002..Using this database we examined changes in the risk profile of patients undergoing isolated coronary artery bypass grafting (CABG) and their outcomes during the decade 1990 to 1999.
- The effect of biventricular pacing after coronary artery bypass grafting: a prospective randomized trial of different pacing modes in patients with reduced left ventricular functionFrank Eberhardt
Medical Clinic II, University of Lubeck, Lubeck, Germany
J Thorac Cardiovasc Surg 137:1461-7. 2009..of biventricular pacing immediately after weaning from cardiopulmonary bypass in patients undergoing coronary artery bypass grafting, but whether these effects can be maintained for the early postoperative period is unclear...
- The effect of biventricular pacing on cardiac function after weaning from cardiopulmonary bypass in patients with reduced left ventricular function: a pressure-volume loop analysisThorsten Hanke
Department of Cardiac and Thoracic Vascular Surgery, University of Lubeck, Lubeck, Germany
J Thorac Cardiovasc Surg 138:148-56. 2009Patients with severely reduced left ventricular function undergoing coronary artery bypass grafting have increased complication rates...
- Vasoconstrictor potential of coronary aspirate from patients undergoing stenting of saphenous vein aortocoronary bypass grafts and its pharmacological attenuationPetra Kleinbongard
FRCP, Institut fur Pathophysiologie, Universitatsklinikum Essen, Hufelandstr 55, 45122 Essen, Germany
Circ Res 108:344-52. 2011..Stent implantation into atherosclerotic plaques releases, apart from particulate debris, soluble substances that contribute to impaired microvascular perfusion...
- Superiority of moderate control of hyperglycemia to tight control in patients undergoing coronary artery bypass graftingCastigliano M Bhamidipati
Division of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
J Thorac Cardiovasc Surg 141:543-51. 2011..We sought to determine whether tight control or moderate glycemic control is optimal after coronary artery bypass grafting.
- Multiple arterial grafts improve late survival of patients undergoing coronary artery bypass graft surgery: analysis of 8622 patients with multivessel diseaseChaim Locker
Division of Cardiovascular Surgery, Mayo Clinic, 200 First St SW, Rochester, MN 55905, USA
Circulation 126:1023-30. 2012Use of the left internal mammary artery (LIMA) in multivessel coronary artery disease improves survival after coronary artery bypass graft surgery; however, the survival benefit of multiple arterial (MultArt) grafts is debated.
- Determinant factors of renal failure after coronary artery bypass grafting with on-pump techniqueHossein Ahmadi
Department of Cardiovascular Surgery, Medical Sciences, Tehran Heart Center, University of Tehran, North Kargar Street, Tehran, Iran
Med Princ Pract 18:300-4. 2009The aim of the present study was to investigate the determinant factors of acute renal failure (ARF) after isolated on-pump coronary artery bypass grafting (CABG).
- 30-day readmissions after coronary artery bypass graft surgery in New York StateEdward L Hannan
University at Albany, State University of New York, Albany 12144 3456, USA
JACC Cardiovasc Interv 4:569-76. 2011..The aim of this study was to identify reasons for and predictors of readmission...
- Anti-inflammatory effects of alkaline phosphatase in coronary artery bypass surgery with cardiopulmonary bypassSuzanne Kats
Catharina Hospital, Department of Cardiothoracic Surgery, Eindhoven, The Netherlands
Recent Pat Inflamm Allergy Drug Discov 3:214-20. 2009..administration of bovine intestinal alkaline phosphatase on surgical complications in patients undergoing coronary artery bypass grafting...
- Outcomes in patients with de novo left main disease treated with either percutaneous coronary intervention using paclitaxel-eluting stents or coronary artery bypass graft treatment in the Synergy Between Percutaneous Coronary Intervention with TAXUS and CMarie Claude Morice
Institut Hospitalier Jacques Cartier, 6 avenue du Noyer Lambert, Massy, France
Circulation 121:2645-53. 2010..SYNTAX) trial was designed to assess the optimal revascularization strategy between percutaneous coronary intervention (PCI) and coronary artery bypass grafting (CABG), for patients with left main (LM) and/or 3-vessel coronary disease.
- Long-term safety and efficacy of percutaneous coronary intervention with stenting and coronary artery bypass surgery for multivessel coronary artery disease: a meta-analysis with 5-year patient-level data from the ARTS, ERACI-II, MASS-II, and SoS trialsJoost Daemen
Thoraxcenter, Ba 583, Dr Molewaterplein 40, 3015 GD Rotterdam, Netherlands
Circulation 118:1146-54. 2008..studied clinical outcomes after percutaneous coronary intervention (PCI) with bare metal stenting versus coronary artery bypass grafting (CABG) are underpowered to properly assess safety end points like death, stroke, and myocardial ..
- Effect of intravenous N-acetylcysteine on outcomes after coronary artery bypass surgery: a randomized, double-blind, placebo-controlled clinical trialIsmail El-Hamamsy
Research Center and Department of Surgery, Montreal Heart Institute and Universite de Montreal, Montreal, Quebec, Canada
J Thorac Cardiovasc Surg 133:7-12. 2007..The objective of this study was to evaluate the effects of intravenous N-acetylcysteine on clinical and biochemical outcomes after coronary artery bypass surgery with cardiopulmonary bypass.
- The role of temporary biventricular pacing in the cardiac surgical patient with severely reduced left ventricular systolic functionRudolph F Evonich
William Beaumont Hospital, Royal Oak, Michigan 48073, USA
J Thorac Cardiovasc Surg 136:915-21. 2008..The objective was to evaluate the effects of atrial synchronous biventricular pacing in postoperative patients with severe cardiomyopathy...
- Remote ischaemic preconditioning reduces myocardial injury in patients undergoing cardiac surgery with cold-blood cardioplegia: a randomised controlled trialV Venugopal
The Hatter Cardiovascular Institute, University College London Hospital, 67 Chenies Mews, London WC1E 6HX, UK
Heart 95:1567-71. 2009..preconditioning (RIPC) induced by brief ischaemia and reperfusion of the arm reduces myocardial injury in coronary artery bypass (CABG) surgery patients receiving predominantly cross-clamp fibrillation for myocardial protection...
- Preoperative C-reactive protein levels predict 9-month mortality after coronary artery bypass grafting surgery for the treatment of left main coronary artery stenosisTullio Palmerini
Department of Cardiology, Policlinico S Orsola, University of Bologna, Italy
Eur J Cardiothorac Surg 31:685-90. 2007..However, there are no data regarding the impact of C-reactive protein on mid-term mortality in patients with unprotected left main coronary artery stenosis treated with coronary artery bypass graft.
- The combination of propranolol and magnesium does not prevent postoperative atrial fibrillationA J Solomon
Department of Medicine, Georgetown University Medical Center, Washington, DC 20007, USA
Ann Thorac Surg 69:126-9. 2000..However, the use of magnesium is more controversial. It was our hypothesis that adjunctive magnesium sulfate would improve the efficacy of beta-blockers alone in the prevention of postoperative atrial fibrillation...
- Achieving and sustaining improved quality: lessons from New York State and cardiac surgeryMark R Chassin
Department of Health Policy, Mount Sinai School of Medicine, New York City, USA
Health Aff (Millwood) 21:40-51. 2002..the New York State Department of Health has published annual data on risk-adjusted mortality following coronary artery bypass graft surgery by hospital and surgeon...
- Acute renal failure following open heart surgery: risk factors and prognosisIlknur Bahar
Department of Cardiovascular Surgery, Turkiye Yuksek Ihtisas Hospital, Ankara, Turkey
Perfusion 20:317-22. 2005..Acute renal failure (ARF) development after cardiac surgery carries high mortality and morbidity...
- Medication adherence following coronary artery bypass graft surgery: assessment of beliefs and attitudesUjjaini Khanderia
College of Pharmacy, University of Michigan, Ann Arbor, MI 48109, USA
Ann Pharmacother 42:192-9. 2008The medication management of patients following coronary artery bypass graft (CABG) surgery may include antiplatelet agents, beta-blockers, angiotensin-converting enzyme inhibitors, and statins...
- Outcomes and perioperative hyperglycemia in patients with or without diabetes mellitus undergoing coronary artery bypass graftingCarlos A Estrada
Department of Internal Medicine, The Brody School of Medicine, East Carolina University, Greenville, North Carolina 27858, USA
Ann Thorac Surg 75:1392-9. 2003..between perioperative hyperglycemia and outcomes in patients with and without diabetes mellitus undergoing coronary artery bypass grafting is not well defined...
- The impact of epiaortic ultrasonographic scanning on the risk of perioperative strokeBartolo Zingone
Division of Cardiac Surgery, Ospedali Riuniti, Strada di Fiume 447, 34100 Trieste, Italy
Eur J Cardiothorac Surg 29:720-8. 2006..To assess the impact of epiaortic scanning on the incidence of perioperative stroke in patients undergoing cardiac surgery...
- Clinical implications of the new definition of myocardial infarctionJohn K French
Cardiology Department, Green Lane Hospital, Auckland, New Zealand
Heart 90:99-106. 2004
- Daily comparison of respiratory functions between on-pump and off-pump patients undergoing CABGSerdar Cimen
Thoracic and Cardiovascular Surgery Department, Dr Siyami Ersek Thoracic and Cardiovascular Surgery Center, Istanbul, Turkey
Eur J Cardiothorac Surg 23:589-94. 2003....
- 10-year follow-up of patients with and without mediastinitisJohn H Braxton
Maine Medical Center, Portland, ME, USA
Semin Thorac Cardiovasc Surg 16:70-6. 2004..86,2.58; P < 0.001). The adjusted hazard ratios for patients who survived 6 months postsurgery was 1.70 (CI95% = 1.36,2.13; P < 0.001). Mediastinitis is associated with a marked increase in both acute and long-term mortality rates...
- Influence of tidal volume on left ventricular stroke volume variation measured by pulse contour analysis in mechanically ventilated patientsDaniel A Reuter
Department of Anesthesiology, University of Munich, Marchioninistrasse 15, 81377 Munich, Germany
Intensive Care Med 29:476-80. 2003..This study investigated the influence of the depth of tidal volume (V(t)) on SVV both during the state of fluid responsiveness and after fluid loading in mechanically ventilated patients...
- Effect of diabetes on early and late survival after isolated first coronary bypass surgery in multivessel diseaseAntonio Maria Calafiore
Department of Cardiology and Cardiac Surgery, University G D Annunzio, Chieti, Italy
J Thorac Cardiovasc Surg 125:144-54. 2003..Diabetes has not yet been investigated as a risk factor for early and late cardiac-related death...
- The Society of Thoracic Surgeons 2008 cardiac surgery risk models: part 1--coronary artery bypass grafting surgeryDavid M Shahian
Massachusetts General Hospital, Boston, Massachusetts 02114, USA
Ann Thorac Surg 88:S2-22. 2009..To adjust for these and other changes, all STS risk models have undergone periodic revisions. This report provides a detailed description of the 2008 STS risk model for coronary artery bypass grafting surgery (CABG).
- Transfusion Trigger Trial in Coronary Artery Disease: A Pilot StudyJEFFREY LEE CARSON; Fiscal Year: 2010..recurrent myocardial infarction, emergent percutaneous intervention (angioplasty or stent insertion) or coronary artery bypass graft surgery within 30 days of enrollment compared to a restrictive transfusion strategy...
- Inhibition of GRK2 to Prevent Ventricular Remodeling and Heart Failure After CABGShahab A Akhter; Fiscal Year: 2013DESCRIPTION (provided by applicant): Despite complete revascularization by coronary artery bypass grafting (CABG), long-term survival is markedly inferior for patients who present with depressed left ventricular function post-myocardial ..
- PTEN Gene Therapy for Vein Graft DiseaseChristopher D Kontos; Fiscal Year: 2010..E2F transcription factor demonstrated no benefit for the prevention of vein graft failure in peripheral or coronary artery bypass grafting (CABG). Thus, there is a critical need for novel approaches to prevent vein graft failure...
- The Fat1 Cadherin in Atherosclerotic Vascular DiseaseNICHOLAS E SIBINGA; Fiscal Year: 2013..process in the pathogenesis of clinically important vascular diseases such as atherosclerosis, restenosis, coronary artery bypass graft failure, and arteriosclerosis that occurs in transplanted hearts and kidneys...
- Treatment and Risk Factor Determinants of Cardiovascular Outcomes in BARI 2DMaria Mori Brooks; Fiscal Year: 2013..When coronary artery bypass surgery (CABG) was pre-specified as the intended method of revascularization, prompt revascularization ..
- SMOOTH MUSCLE CELL PROLIFERATION IN HUMAN CORONARY ARTERY BYPASS GRAFTSDevendra K Agrawal; Fiscal Year: 2012..Invasive techniques such as coronary artery bypass grafting (CABG) using the saphenous vein (SV) or internal mammary artery (IMA) are used to alleviate the ..
- Acute Coronary Syndrome Outcomes for Medicare PatientsSALLY STEARNS; Fiscal Year: 2009..early mechanical myocardial revascularization with either percutaneous intervention with stents (PCIS) or coronary artery bypass grafting (CABG)...
- Prasugrel for prevention of early saphenous vein graft thrombosisEmmanouil Brilakis; Fiscal Year: 2013..However, in patients who undergo coronary artery bypass graft surgery, it remains unknown whether prasugrel may decrease thrombus formation in saphenous vein ..
- ACCF-STS Database Collaboration on the Comparative Effectiveness of PCI and CABGWilliam S Weintraub; Fiscal Year: 2010..of the two forms of coronary revascularization therapy, percutaneous coronary intervention (PCI) and coronary artery bypass graft (CABG) surgery...
- Autogeneic Mitochondria: Surgical CardioprotectionJames D McCully; Fiscal Year: 2013..a time frame reasonable within the clinical interventions of both coronary artery bypass grafting (CABG) and percutaneous coronary intervention for coronary revascularization for ST segment ..
- Hepcidin Lateral Flow Device for Prediction of Acute Kidney InjuryMARK EDWARD WESTERMAN; Fiscal Year: 2013..AKI) is a common, severe complication of cardiopulmonary bypass (CPB) assisted surgeries, and include coronary artery bypass grafts, valve replacements, aortic aneurisms, and organ transplants...
- Activation of sirtuins to prevent adverse cardiac remodeling after CABGMahesh P Gupta; Fiscal Year: 2013..Even after complete revascularization by coronary artery bypass grafting (CABG) patients with MI (myocardial infarction) often develop adverse ventricular remodeling in ..
- Antithrombotic Aptamers and AntidotesBRUCE ALAN SULLENGER; Fiscal Year: 2013..a number of clinical procedures including percutaneous coronary interventions (PCI, "angioplasties"), coronary artery bypass graft (CABG) surgery and other surgeries, as well as dialysis...
- Mitochondrial Dysfunction and Susceptibility to Atrial Fibrillation in the ElderlArshad Jahangir; Fiscal Year: 2013..These aims will be achieved using atrial tissue obtained from patients undergoing coronary artery bypass surgery without or with risk factors for AF (heart failure, hypertension, or mitral regurgitation) or a ..
- Prolonged Clopidogrel Use After Drug-Eluting and Bare-Metal Coronary StentingScott Kinlay; Fiscal Year: 2013..on the secondary endpoints of cardiac death, ischemic stroke, coronary revascularization with PCI or coronary artery bypass surgery, and major bleeding...
- Methods To Reduce Vein Harvest InjuryJoyce Cheung-Flynn; Fiscal Year: 2013..human saphenous vein (HSV) continues to be the most widely used conduit for approximately 1,000,000 coronary artery bypass grafting (CABG) and peripheral vascular (PV) revascularization procedures performed each year...
- Racial disparities in access to high quality hospitals for coronary heart diseaseIoana Popescu; Fiscal Year: 2013..are less likely to receive care for acute myocardial infarction, percutaneous coronary intervention, and coronary artery bypass surgery in high quality hospitals...
- Biomarkers in Acute Kidney InjuryJoseph Bonventre; Fiscal Year: 2009..aims in the R21 phase, we propose in the R33 phase a prospective study involving 400 patients undergoing coronary artery bypass graft surgery and 350 patients admitted to the medical intensive care unit...
- MYOCARDIAL PROTECTION: REPERFUSION INJURY AMELIORATIONJames D McCully; Fiscal Year: 2010Demographic studies have shown that the mean age of patients requiring coronary artery bypass surgery (CABG) is 68 years with approximately 44% of these patients being female...
- Moral Hazard in Less Invasive Surgical Technology for Coronary Artery DiseaseMichael Grossman; Fiscal Year: 2011..Percutaneous coronary intervention (PCI)--the newer and less invasive procedure-- and coronary artery bypass graft (CABG) surgery are the surgical interventions for CAD considered...
- Small heat shock proteins in surgically-induced myocardial stunningRichard T Clements; Fiscal Year: 2012The majority of coronary artery bypass grafting (CABG) and valve repair surgeries use cardioplegia and cardiopulmonary bypass (CP/CPB) to respectively arrest the heart and systemically circulate oxygenated blood...
- CaMKII regulates key mechanisms of vascular response to injury in vivoISABELLA MARIA GRUMBACH; Fiscal Year: 2013..Neointima formation and remodeling occur in vein graft failure after coronary artery bypass surgery, after balloon angioplasty and surgical endarterectomy and have a significant impact in terms of ..
- Smart Polymer Based MK2 Inhibitor to Suppress Vascular Graft Intimal HyperplasiaCRAIG LEWIS DUVALL; Fiscal Year: 2012DESCRIPTION (provided by applicant): Coronary artery bypass grafting (CABG) with autologous conduits effectively alleviates ischemic heart disease, but long-term graft patency is problematic...
- Miniaturized Distal Vibration System for Penetration of Vascular OcclusionsSTEPHANIE ADI HARRINGTON; Fiscal Year: 2010..to the patient including reduced angina symptoms, improved left ventricular function, reduced need for Coronary Artery Bypass Graft (CABG), and a lower incidence of death or Myocardial Infarction (MI), but success rates are still ..
- STICH Trial-Statistical and Data Coordinatiing CenterKerry L Lee; Fiscal Year: 2010..LV) dysfunction who have coronary artery disease (CAD) amenable to surgical revascularization: 1) Coronary artery bypass grafting (CABG) with intensive medical therapy (MED) improves long-term survival compared to MED alone; 2) ..
- STICH Trial-Coordinating CenterRobert H Jones; Fiscal Year: 2011..LV) dysfunction who have coronary artery disease (CAD) amenable to surgical revascularization: 1) Coronary artery bypass grafting (CABG) with intensive medical therapy (MED) improves long-term survival compared to MED alone; 2) ..
- PRESERVATION OF ENDOTHELIAL DEPENDENT RELAXATIONColleen M Brophy; Fiscal Year: 2013..b>Coronary artery bypass grafting (CABG) is one of the most effective treatments for advanced coronary artery disease (CAD) and ..
- Differences in Quality, Cost, and Access between VA and Fee Basis CABG and PCITHOMAS MCMILLIN MADDOX; Fiscal Year: 2013..Background. VHA purchases 19% of the elective Coronary Artery Bypass Graft (CABG) and 22% of the elective Percutaneous Coronary Intervention (PCI) that it sponsors for ..
- Pulmonary Rehabiltation before Lung Cancer ResectionROBERTO PABLO BENZO; Fiscal Year: 2013..ultimately translate these improvements to all thoracic surgical procedures (such as esophageal cancer, coronary artery bypass surgery, etc...
- Comparative Effectiveness of Coronary StentsEdward Hannan; Fiscal Year: 2013..are to compare longer-term mortality, myocardial infarction, and subsequent revascularization (PCI or coronary artery bypass graft surgery) for different pairs of coronary stents including BMS and the two generations of DES...
- Development of a Microstructurally Inspired and Compliance Matched Tissue EngineeJONATHAN PIETER VANDE GEEST; Fiscal Year: 2013..In 2006 alone, CAD killed 425,245 people, and 176,138 coronary artery bypass grafts were implanted in patients ...
- Mussel-inspired self-healing hydrogels for vascular tissue repairDOMINIC EDWARD FULLENKAMP; Fiscal Year: 2012..Currently, no synthetic materials exist that are ideal for small vessel grafts such as those used in coronary artery bypass. PUBLIC HEALTH RELEVANCE: For those patients who do not have suitable grafts (usually from veins in the ..
- Physician Referral &Mental-Disorder Related Disparities in CABG QualityYue Li; Fiscal Year: 2011..infarction, patients with mental disorders tend to under-use invasive cardiac procedures including coronary artery bypass graft (CABG) surgery...
- Using Clinically-Enhanced Claims Data to Guide Selection of Coronary ProceduresHAROLD KILBURN; Fiscal Year: 2010..provided by applicant): The goal of this research program is to examine the comparative effectiveness of coronary artery bypass graft (CABG) procedures and percutaneous coronary artery interventions (PCI)...
- Hormones and Sexual Function Predict Outcomes in Revascularized Men with DiabetesMARY A MCLAUGHLIN; Fiscal Year: 2013..study is a multi-institutional randomized controlled trial comparing revascularization with either coronary artery bypass graft surgery (CABG) or with drug eluting stents in 2,400 patients with DM and multi-vessel CAD...
- Intracranial Atherosclerosis and predictors of Post-CABG DepressionHochang B Lee; Fiscal Year: 2013DESCRIPTION (provided by applicant): Depression after coronary artery bypass graft (CABG) surgery is common (up to 40%) and increases risk of cardiac morbidity and mortality in the first year by more than two fold...
- A Bioactive Prosthetic Vascular GraftMATTHEW DOUGLAS PHANEUF; Fiscal Year: 2012..grafts could be utilized in peripheral bypass (specifically below-knee reconstruction) as well as for coronary artery bypass. Thus, the potential annual market value for an "off-the-shelf" bioactive synthetic arterial bypass graft ..
- Blended Collaborative Care for Heart Failure and Co-Morbid DepressionBRUCE LAWRENCE ROLLMAN; Fiscal Year: 2013..and we recently demonstrated its clinical and cost-effectiveness at treating depression following coronary artery bypass graft surgery...
- Cell Instructive Materials For Engineering Vascular GraftsRobert E Akins; Fiscal Year: 2013..are significant post-procedure problems with nearly 50% of autologous vein grafts used in peripheral or coronary artery bypass surgery failing over time due to maladaptive vessel remodeling...
- Cleveland Clinic Cardiothoracic Collaborative Clinical Center - C6Eugene Blackstone; Fiscal Year: 2013..For 30+ years, the specialty has been dominated by coronary artery bypass grafting (CABG)...
- Optimizing Prevention of Healthcare-Acquired Infections After Cardiac SurgeryDonald S Likosky; Fiscal Year: 2013DESCRIPTION (provided by applicant): More than 400,000 coronary artery bypass grafting (CABG) procedures are performed every year in the United States (U.S.)...
- National Claims-Based Quality Measures for Surgical Site InfectionsRichard Platt; Fiscal Year: 2013..We will 1) extend our previously successful claims-based surveillance following coronary artery bypass graft (CABG) surgery and hip arthroplasty to identify hospitals with an unusually high risk of SSI ..
- Mitral Regurgitation, Heart Failure and Coronary Disease: Benefits to MV Repair?Robert Michler; Fiscal Year: 2012..second clinical trial will evaluate the appropriateness of current clinical practice which maintains that coronary artery bypass surgery (CABG) alone is sufficient to treat patients with coronary artery disease (CAD) and mild to ..
- Mannose binding lectin and outcomes following CABGGREGORY L contact STAHL; Fiscal Year: 2010..occurs following successful thrombolytic therapy, percutaneous transluminal coronary angioplasty and coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB)...
- Myocardial Salvage With a Novel Reperfusion TherapyCONSTANCE WILSON; Fiscal Year: 2005..Reperfusion injury of the heart following angioplasty procedures and coronary artery bypass graft surgery can affect the length of hospitalization, cost of hospitalization, functional capacity of ..
- Statistical Methods for Complex Data in Cardiovascular DiseaseAnastasios A Tsiatis; Fiscal Year: 2013..g., in a study to compare endoscopic vs. open vein graft harvesting in patients undergoing coronary artery bypass graft surgery, Medicare claims data may misclassify the technique used in some pro- portion of patients...
- Biodegradable Synthetic Vascular GraftYadong Wang; Fiscal Year: 2013..immediately as a non-thrombogenic conduit for blood flow in a similar fashion as a saphenous vein in coronary artery bypass surgery...
- Long-Term Survival Following Coronary RevascularizationsEdward Hannan; Fiscal Year: 2010..Coronary revascularization procedures (i.e., coronary artery bypass graft (CABG) surgery and percutaneous coronary interventions (PCI)) are among the most frequently ..
- Minimally Invasive Ventricular Polymeric Injection for Treatment of Heart FailureGhassan S Kassab; Fiscal Year: 2013..mathematical (finite element models of failing left ventricles that have been treated with Algisyl-LVR + coronary artery bypass grafting or Algisyl-LVR alone...
- Operative Strategies To Reduce Cerebral Embolic Events During CABGMichael Halkos; Fiscal Year: 2013DESCRIPTION (provided by applicant): One of the most devastating complications of coronary artery bypass surgery (CABG) is postoperative stroke...
- Improved Estimates of the Comparative Treatment Effects of CABG and PCIMark A Hlatky; Fiscal Year: 2010..several statistical approaches to derive reliable treatment comparisons from observational data using coronary artery bypass graft surgery and coronary angioplasty as the test case...
- Hybrid revascularization vs percutaneous coronary intervention: A Planning GrantJOHN DANIEL contact PUSKAS; Fiscal Year: 2010..The enormous and increasing prevalence of coronary artery disease (CAD), ongoing innovation in coronary artery bypass grafting (CABG), percutaneous coronary intervention (PCI) and medical therapy, as well as the costs of ..
- EQUITY OF INPATIENT SURGERY UTILIZATION IN CALIFORNIAMita Giacomini; Fiscal Year: 1992..The utilization of seven surgical procedures will be analyzed: coronary artery bypass, pacemaker implant, carotid endarterectomy, hip arthroplasty/replacement, lithotripsy, kidney ..
- Implantable construct for architectural control of re-vascularization of ischemicMichael Yang; Fiscal Year: 2013..MicroBridge will serve as an adjunct delivered during coronary artery bypass surgery that would direct vascularization in the microvasculature to reperfuse regions of ischemia not ..
- Dynamic MRI for Myocardial Perfusion and ViabilityEDWARD VR DI BELLA; Fiscal Year: 2010..the methods to longitudinal studies of patients undergoing bone marrow stem cell therapy as an adjunct to coronary artery bypass grafting...
- Enhancing vein graft viabilityMICHAEL JAMES OSGOOD; Fiscal Year: 2012..Preliminary data has shown that 40% of HSV harvested for coronary artery bypass procedures have no functional viability...
- Development of an antidote-controlled FIXa inhibitorChristopher Rusconi; Fiscal Year: 2004Anticoagulant therapy is required to perform a number of clinical procedures including coronary artery bypass graft (CABG) surgery and other "open-heart" surgeries, percutaneous coronary interventions (PCI, "angioplasties"), and dialysis; ..
- Prevention of Vein Graft Intimal Hyperplasia with Optimized Human ApyraseRidong Chen; Fiscal Year: 2012DESCRIPTION (provided by applicant): The saphenous vein is the most commonly used graft for coronary artery bypass and peripheral bypass surgery, but has poor patency...
- Bradykinin Receptor Antagonism During Cardiopulmonary BypassMias Pretorius; Fiscal Year: 2010..In fact, approximately 20% of all blood products transfused are associated with coronary artery bypass grafting procedures...
- Cleveland Clinic Cardiothoracic Collaborative Clinical Center (C6)Bruce Lytle; Fiscal Year: 2013..During the nearly 50-year history of cardiac surgery, 30+ years were dominated by coronary artery bypass grafting (CABG)...
- Reducing Risk in Cardiac Rehabilitation: Partners Together in Health (PaTH) InterBernice Yates; Fiscal Year: 2009..by applicant): Long-term maintenance of lifestyle changes to reduce cardiovascular risk factors after coronary artery bypass graft (CABG) surgery is essential to positively influence health outcomes...
- Microparticles in stored RBC as potential mediators in transfusion complicationsWenche Jy; Fiscal Year: 2012..is a clinical study to directly test the hypothesis by administering to randomized patients scheduled for coronary artery bypass surgery either conventional PC (Group 1) or PC washed prior to transfusion to deplete MP (Group 2)...
- UTILIZATION OF RESEARCH ON CARDIOVASCULAR TECHNOLOGIESPAUL WORTMAN; Fiscal Year: 1990The proposed research seeks to use meta-analytic methods to exploit the rather considerable databases on coronary artery bypass graft surgery, lytic agents for myocardial infarction, carotid endarterectomy, and drug interventions for ..
- Simulation of Coronary Artery Bypass Graft and Surgical Ventricular RestorationJULIUS MATTEO GUCCIONE; Fiscal Year: 2010..b>Coronary artery bypass grafting (CABG) and surgical ventricular restoration (SVR) are the two surgical options included in the ..
- Post Coronary Bypass Atrial Arrhythmic Prediction RuleRod Passman; Fiscal Year: 2006The proposed study seeks to develop and validate a clinical prediction rule for post-coronary artery bypass grafting (CABG) atrial fibrillation and atrial flutter (AF)...
- RECEPTOR KINASE GENE THERAPY FOR NEOINTIMAL HYPERPLASIANeil Freedman; Fiscal Year: 2002Percutaneous transluminal coronary angioplasty (PTCA) and coronary artery bypass graft surgery (CABG) are each used to treat approximately 400,000 coronary artery disease patients annually in the United States...
- CORONARY ARTERY BYPASS ENDARTERECTOMY STAGING TRIALJohn Ricotta; Fiscal Year: 2002..From 5-12 percent of patients who present for Coronary Artery Bypass Grafting (CABG) will have significant stenosis at the carotid bifurcation...
- ASSESSING RISK FACTORS AND HOSPITAL QUALITY FOR CABGEdward Hannan; Fiscal Year: 1992..are (1) to determine which preoperative risk factors are significantly related to the probability of a coronary artery bypass graft (CABG) patient experiencing an in-hospital mortality or perioperative complication, and (b) to use ..