myocardial revascularization

Summary

Summary: The restoration of blood supply to the myocardium. (From Dorland, 28th ed)

Top Publications

  1. ncbi Complete myocardial revascularization: between myth and reality
    Marco Zimarino
    Institute of Cardiology and Centre of Excellence on Aging, G D Annunzio University, Ospedale S Camillo de Lellis, Via Forlanini, 50, 66100 Chieti, Italy
    Eur Heart J 26:1824-30. 2005
  2. ncbi Hibernating myocardium: another piece of the puzzle falls into place
    Shahbudin H Rahimtoola
    J Am Coll Cardiol 47:978-80. 2006
  3. ncbi Strict glycemic control reduces EuroSCORE expected mortality in diabetic patients undergoing myocardial revascularization
    Cosimo D'Alessandro
    Institute of Cardiology, Division of Thoracic and Cardiovascular Surgery, Centre Hospitalier Universitaire Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Université Pierre et Marie Curie Paris, Paris, France
    J Thorac Cardiovasc Surg 134:29-37. 2007
  4. ncbi Early invasive vs conservative treatment strategies in women and men with unstable angina and non-ST-segment elevation myocardial infarction: a meta-analysis
    Michelle O'Donoghue
    TIMI Study Group, Brigham and Women s Hospital, 350 Longwood Ave, First Floor, Boston, MA 02115, USA
    JAMA 300:71-80. 2008
  5. ncbi Hypoxemia after myocardial revascularization: analysis of risk factors
    Tais Felix Szeles
    Serviço de Anestesiologia e Terapia Intensiva Cirúrgica do Instituto do Coração InCor Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo HC FMUSP, Sao Paulo, SP
    Rev Bras Anestesiol 58:124-36. 2008
  6. ncbi The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction
    R J Kim
    Feinberg Cardiovascular Research Institute, and Department of Medicine, Northwestern University Medical School, Chicago, IL 60611 3008, USA
    N Engl J Med 343:1445-53. 2000
  7. ncbi ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise th
    Jeffrey L Anderson
    J Am Coll Cardiol 50:e1-e157. 2007
  8. ncbi Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD)
    Lars Ryden
    Department of Cardiology, Karolinska University Hospital, Sweden
    Eur Heart J 28:88-136. 2007
  9. ncbi Effect of arterial revascularisation on survival: a systematic review of studies comparing bilateral and single internal mammary arteries
    D P Taggart
    Oxford Heart Centre, John Radcliffe Hospital, OX3 9DU, Oxford, UK
    Lancet 358:870-5. 2001
  10. ncbi 5-year outcome of an interventional strategy in non-ST-elevation acute coronary syndrome: the British Heart Foundation RITA 3 randomised trial
    K A A Fox
    Centre for Cardiovascular Science, Department of Medical and Radiological Sciences, University of Edinburgh, Edinburgh EH16 4SB, UK
    Lancet 366:914-20. 2005

Research Grants

  1. Acute Coronary Syndrome Outcomes for Medicare Patients
    SALLY STEARNS; Fiscal Year: 2009
  2. STICHES
    Eric J Velazquez; Fiscal Year: 2013
  3. Molecular regulation of vein graft adapation
    Alan Dardik; Fiscal Year: 2013
  4. SKELETAL MUSCLE FOR MYOCARDIAL ASSISTANCE
    JOHN MANNION; Fiscal Year: 1993
  5. Imaging and Laser Revascularization in Hibernation
    Lynne Johnson; Fiscal Year: 2003
  6. IMPROVING OUTCOMES AND QUALITY OF LIFE AFTER CABG
    Mary Charlson; Fiscal Year: 1999
  7. CARDIAC SURGERY AND CEREBROVASCULAR COMPLICATIONS
    TODD TROOST; Fiscal Year: 1993
  8. Vector Identification and Gene Delivery Approach in Pigs
    JUDITH GWATHMEY; Fiscal Year: 2007
  9. Vector Identification and Gene Delivery Approach in Pigs
    JUDITH GWATHMEY; Fiscal Year: 2005
  10. NONINVASIVE PROTON BEAM MYOCARDIAL REVASCULARIZATION
    Keith March; Fiscal Year: 2000

Detail Information

Publications248 found, 100 shown here

  1. ncbi Complete myocardial revascularization: between myth and reality
    Marco Zimarino
    Institute of Cardiology and Centre of Excellence on Aging, G D Annunzio University, Ospedale S Camillo de Lellis, Via Forlanini, 50, 66100 Chieti, Italy
    Eur Heart J 26:1824-30. 2005
    b>Myocardial revascularization in patients with multi-vessel coronary artery disease may be accomplished, by percutaneous interventions or surgery, either on all diseased lesions or directed to selectively targeted coronary segments...
  2. ncbi Hibernating myocardium: another piece of the puzzle falls into place
    Shahbudin H Rahimtoola
    J Am Coll Cardiol 47:978-80. 2006
  3. ncbi Strict glycemic control reduces EuroSCORE expected mortality in diabetic patients undergoing myocardial revascularization
    Cosimo D'Alessandro
    Institute of Cardiology, Division of Thoracic and Cardiovascular Surgery, Centre Hospitalier Universitaire Pitie Salpetriere, Assistance Publique Hopitaux de Paris, Université Pierre et Marie Curie Paris, Paris, France
    J Thorac Cardiovasc Surg 134:29-37. 2007
    We sought to evaluate the effect of a strict glycemic control protocol on a series of diabetic patients undergoing surgical myocardial revascularization.
  4. ncbi Early invasive vs conservative treatment strategies in women and men with unstable angina and non-ST-segment elevation myocardial infarction: a meta-analysis
    Michelle O'Donoghue
    TIMI Study Group, Brigham and Women s Hospital, 350 Longwood Ave, First Floor, Boston, MA 02115, USA
    JAMA 300:71-80. 2008
    ..Although an invasive strategy is frequently used in patients with non-ST-segment elevation acute coronary syndromes (NSTE ACS), data from some trials suggest that this strategy may not benefit women...
  5. ncbi Hypoxemia after myocardial revascularization: analysis of risk factors
    Tais Felix Szeles
    Serviço de Anestesiologia e Terapia Intensiva Cirúrgica do Instituto do Coração InCor Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo HC FMUSP, Sao Paulo, SP
    Rev Bras Anestesiol 58:124-36. 2008
    Severe hypoxemia is complication frequently seen in the immediate postoperative period of myocardial revascularization (MR), increasing the duration of mechanical ventilation, the incidence of pulmonary infections, hospital costs, and ..
  6. ncbi The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction
    R J Kim
    Feinberg Cardiovascular Research Institute, and Department of Medicine, Northwestern University Medical School, Chicago, IL 60611 3008, USA
    N Engl J Med 343:1445-53. 2000
    ..We hypothesized that the results of contrast-enhanced MRI can be used to predict whether regions of abnormal ventricular contraction will improve after revascularization in patients with coronary artery disease...
  7. ncbi ACC/AHA 2007 guidelines for the management of patients with unstable angina/non-ST-Elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise th
    Jeffrey L Anderson
    J Am Coll Cardiol 50:e1-e157. 2007
  8. ncbi Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD)
    Lars Ryden
    Department of Cardiology, Karolinska University Hospital, Sweden
    Eur Heart J 28:88-136. 2007
  9. ncbi Effect of arterial revascularisation on survival: a systematic review of studies comparing bilateral and single internal mammary arteries
    D P Taggart
    Oxford Heart Centre, John Radcliffe Hospital, OX3 9DU, Oxford, UK
    Lancet 358:870-5. 2001
    ..We systematically reviewed published studies of bilateral versus single IMA grafts in CABG to assess any differences in survival...
  10. ncbi 5-year outcome of an interventional strategy in non-ST-elevation acute coronary syndrome: the British Heart Foundation RITA 3 randomised trial
    K A A Fox
    Centre for Cardiovascular Science, Department of Medical and Radiological Sciences, University of Edinburgh, Edinburgh EH16 4SB, UK
    Lancet 366:914-20. 2005
    ..We tested whether an interventional strategy (routine angiography followed by revascularisation) was better than a conservative strategy (ischaemia-driven or symptom-driven angiography) over 5 years' follow-up...
  11. ncbi Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology
    Kim Fox
    Department of Cardiology, Royal Brompton Hospital, London, UK
    Eur Heart J 27:1341-81. 2006
  12. ncbi Incremental prognostic value of multi-slice computed tomography coronary angiography over coronary artery calcium scoring in patients with suspected coronary artery disease
    Jacob M van Werkhoven
    Department of Cardiology, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Eur Heart J 30:2622-9. 2009
    ..The purpose of this study was to assess the relationship between calcium scoring (CS) and multi-slice computed tomography coronary angiography (MSCTA) and to determine if MSCTA has an incremental prognostic value to CS...
  13. ncbi 5-year clinical outcomes in the ICTUS (Invasive versus Conservative Treatment in Unstable coronary Syndromes) trial a randomized comparison of an early invasive versus selective invasive management in patients with non-ST-segment elevation acute coronary
    Peter Damman
    Department of Cardiology, Cardiac Catheterization Laboratory B2 137, Academic Medical Center University of Amsterdam, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands
    J Am Coll Cardiol 55:858-64. 2010
    ..We present the 5-year clinical outcomes according to treatment strategy with additional risk stratification of the ICTUS (Invasive versus Conservative Treatment in Unstable coronary Syndromes) trial...
  14. ncbi Effect of an invasive strategy on in-hospital outcome in elderly patients with non-ST-elevation myocardial infarction
    Timm Bauer
    Herzzentrum Ludwigshafen, Department of Cardiology, Medizinische Klinik B, Bremserstrasse 79, D 67063 Ludwigshafen, Germany
    Eur Heart J 28:2873-8. 2007
    ..We sought to investigate the impact of an invasive treatment in elderly patients presenting with non-ST elevation myocardial infarction (NSTEMI) in clinical practice...
  15. ncbi Left internal thoracic artery-radial artery composite grafts as the technique of choice for myocardial revascularization in elderly patients: a prospective randomized evaluation
    Claudio Muneretto
    Division of Cardiac Surgery, University of Brescia Medical School, Italy
    J Thorac Cardiovasc Surg 127:179-84. 2004
    The technique of choice for myocardial revascularization in elderly patients remains a debated issue...
  16. ncbi Socioeconomic inequities in invasive cardiac procedures among patients with incident angina pectoris or myocardial infarction
    Tiina Hetemaa
    National Research and Development Centre for Welfare and Health STAKES, Outcomes and Equity Research, Helsinki, Finland
    Scand J Public Health 34:116-23. 2006
    ..This study prospectively examined socioeconomic differences in the use of cardiac procedures in a national cohort of incident coronary patients...
  17. ncbi Five-year outcomes of surgical or percutaneous myocardial revascularization in diabetic patients
    Giovanni Andrea Contini
    Unita Operativa di Cardiochirurgia, Dipartimento Cardio Nefro Polmonare, Azienda Ospedaliero Universitaria di Parma, Italy Electronic address
    Int J Cardiol 168:1028-33. 2013
    ..The study compares five-year clinical outcomes of CABG vs PCI in a real world population of diabetic patients with multivessel coronary disease since it is not clear whether to prefer surgical or percutaneous revascularization...
  18. ncbi Re-OPCAB vs. Re-CABG for myocardial revascularization
    A Schutz
    Department of Cardiac Surgery, Herzklinik am Augustinum, Munchen, Germany
    Thorac Cardiovasc Surg 49:144-8. 2001
    ..The present study compared redo coronary artery bypass grafting (Re-OPCAB) techniques with conventional redo coronary artery bypass grafting (Re-CABG) with particular focus on myocardial damage and clinical outcome parameters...
  19. ncbi The salvaged area at risk in reperfused acute myocardial infarction as visualized by cardiovascular magnetic resonance
    Matthias G Friedrich
    Stephenson Cardiovascular Magnetic Resonance Centre at the Libin Cardiovascular Institute of Alberta, Department of Cardiac Sciences, University of Calgary, Alberta, Canada
    J Am Coll Cardiol 51:1581-7. 2008
    ..We aimed to characterize the tissue changes within the perfusion bed of infarct-related vessels in patients with acutely reperfused myocardial infarction (MI) using cardiovascular magnetic resonance (CMR)...
  20. ncbi Comparison of the prognostic value of normal regadenoson with normal adenosine myocardial perfusion imaging with propensity score matching
    Fahad M Iqbal
    Tulane University Heart and Vascular Institute, New Orleans, LA 70112, USA
    JACC Cardiovasc Imaging 5:1014-21. 2012
    ..The aim of this study was to test the hypothesis that patients with normal regadenoson myocardial perfusion imaging (MPI) have a low rate of cardiac events, similar to patients with normal adenosine MPI...
  21. ncbi Impact of ischaemia and scar on the therapeutic benefit derived from myocardial revascularization vs. medical therapy among patients undergoing stress-rest myocardial perfusion scintigraphy
    Rory Hachamovitch
    Section of Cardiovascular Imaging, Department of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH, USA
    Eur Heart J 32:1012-24. 2011
    ..Although pre-revascularization ischaemia testing is recommended, the interaction between the extent of ischaemia and myocardial scar with performance of revascularization on patient survival is unclear...
  22. pmc Intervention in acute coronary syndromes: do patients undergo intervention on the basis of their risk characteristics? The Global Registry of Acute Coronary Events (GRACE)
    K A A Fox
    Cardiovascular Research, Division of Medical and Radiological Sciences, University of Edinburgh, Edinburgh EH16 4SB, UK
    Heart 93:177-82. 2007
    ..To determine whether revascularisation is more likely to be performed in higher-risk patients and whether the findings are influenced by hospitals adopting more or less aggressive revascularisation strategies...
  23. ncbi [Heart rate variability and pulmonary infections after myocardial revascularization]
    Paulo Rogério Corrêa
    Fundação Faculdade Regional de Medicina de São José do Rio Preto, Sao Paulo, Brasil
    Arq Bras Cardiol 95:448-56. 2010
    ..The assessment of HRV using nonlinear dynamics methods in the preoperative period of surgical myocardial revascularization could be predictive of morbidity such as pulmonary infections in the postoperative period.
  24. ncbi 5-year clinical outcomes after sirolimus-eluting stent implantation insights from a patient-level pooled analysis of 4 randomized trials comparing sirolimus-eluting stents with bare-metal stents
    Adriano Caixeta
    Columbia University Medical Center and the Cardiovascular Research Foundation, New York, New York, USA
    J Am Coll Cardiol 54:894-902. 2009
    ..Five-year clinical follow-up has been scheduled per protocol by the 4 Cypher (Cordis/Johnson & Johnson, Warren, New Jersey) sirolimus-eluting stent (SES) versus bare-metal stent (BMS) randomized trials...
  25. ncbi Impact of completeness of percutaneous coronary intervention revascularization on long-term outcomes in the stent era
    Edward L Hannan
    State University of New York, University at Albany, Rensselaer, NY 12144 3456, USA
    Circulation 113:2406-12. 2006
    ....
  26. ncbi Outcomes in patients with diabetes mellitus undergoing percutaneous coronary intervention in the current era: a report from the Prevention of REStenosis with Tranilast and its Outcomes (PRESTO) trial
    Verghese Mathew
    Mayo Clinic, Gonda 5 South MS 130, 200 First Street SW, Rochester, Minn 55905, USA
    Circulation 109:476-80. 2004
    ..The aim of this study was to determine the influence of diabetes on 9-month outcomes of patients undergoing PCI in the current era...
  27. ncbi Percutaneous coronary intervention versus conservative therapy in nonacute coronary artery disease: a meta-analysis
    Demosthenes G Katritsis
    Department of Cardiology, Athens Euroclinic, Athens, Greece
    Circulation 111:2906-12. 2005
    ..Therefore, we performed a meta-analysis of 11 randomized trials comparing PCI to conservative treatment in patients with stable CAD...
  28. ncbi Shifting the open-artery hypothesis downstream: the quest for optimal reperfusion
    M T Roe
    Duke Clinical Research Institute, Durham, North Carolina 27715, USA
    J Am Coll Cardiol 37:9-18. 2001
    ..Thus, as the reperfusion era moves into the next millennium, the open-artery hypothesis is expected to shift downstream and guide efforts to further improve myocardial salvage and clinical outcomes after acute MI...
  29. pmc Early outcomes in the elderly: a meta-analysis of 4921 patients undergoing coronary artery bypass grafting--comparison between off-pump and on-pump techniques
    S S Panesar
    Department of Surgical Oncology and Technology, Imperial College, London, UK
    Heart 92:1808-16. 2006
    ..To assess early outcomes in the elderly population undergoing coronary revascularisation with and without cardiopulmonary bypass (CPB)...
  30. pmc A comparison of bare-metal and drug-eluting stents for off-label indications
    Oscar C Marroquin
    Cardiovascular Institute, University of Pittsburgh, Pittsburgh, USA
    N Engl J Med 358:342-52. 2008
    ..Recent reports suggest that off-label use of drug-eluting stents is associated with an increased incidence of adverse events. Whether the use of bare-metal stents would yield different results is unknown...
  31. ncbi Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy
    Leslee J Shaw
    Emory University School of Medicine, Atlanta, GA 30306, USA
    Circulation 117:1283-91. 2008
    ....
  32. ncbi The effect of completeness of revascularization on event-free survival at one year in the ARTS trial
    Marcel J B M van den Brand
    Thoraxcenter, Department of Cardiology, University Hospital Dijkzigt, Rotterdam, The Netherlands
    J Am Coll Cardiol 39:559-64. 2002
    ..We sought to assess the relationship between completeness of revascularization and adverse events at one year in the ARTS (Arterial Revascularization Therapies Study) trial...
  33. ncbi Hypotheses, design, and methods for the Bypass Angioplasty Revascularization Investigation 2 Diabetes (BARI 2D) Trial
    Maria Mori Brooks
    Department of Epidemiology, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA
    Am J Cardiol 97:9G-19G. 2006
    ....
  34. ncbi Plasma concentration of C-reactive protein and risk of developing peripheral vascular disease
    P M Ridker
    Department of Medicine, Brigham and Women s Hospital, Boston, Mass 02115 1204, USA
    Circulation 97:425-8. 1998
    ..Whether increased levels of CRP are also associated with the development of symptomatic peripheral arterial disease (PAD) is unknown...
  35. ncbi Prognostic value of coronary computed tomographic angiography for prediction of cardiac events in patients with suspected coronary artery disease
    Martin Hadamitzky
    Klinik für Herz und Kreislauferkrankungen, Deutsches Herzzentrum Munchen, Technische Universitat Munchen, Munich, Germany
    JACC Cardiovasc Imaging 2:404-11. 2009
    ..We assessed the rate of cardiac events after detection or exclusion of obstructive coronary artery disease (CAD) by coronary computed tomography angiography (CCTA)...
  36. pmc Early revascularization and long-term survival in cardiogenic shock complicating acute myocardial infarction
    Judith S Hochman
    Cardiovascular Clinical Research Center, New York University School of Medicine, New York 10016, USA
    JAMA 295:2511-5. 2006
    ....
  37. ncbi Prognostic value of cardiac computed tomography angiography: a systematic review and meta-analysis
    Edward A Hulten
    Cadiology Service, Walter Reed Army Medical Center, Washington, DC, USA
    J Am Coll Cardiol 57:1237-47. 2011
    ..The purpose of this study was to systematically review and perform a meta-analysis of the ability of cardiac computed tomography angiography (CCTA) to predict future cardiovascular events and death...
  38. ncbi Heart rate recovery and impact of myocardial revascularization on long-term mortality
    Michael S Chen
    Department of Cardiovascular Medicine, Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Circulation 110:2851-7. 2004
    ..We sought to determine whether HRR can identify patients likely to have improved survival after revascularization...
  39. ncbi Does the completeness of revascularization contribute to an improved early survival in patients up to 70 years of age?
    B R Osswald
    Department of Cardiac Surgery, University of Heidelberg, Im Neuenheimer Feld 110, 69120 Heidelberg, Germany
    Thorac Cardiovasc Surg 49:373-7. 2001
    ..However, for the younger patient group, there is no conclusive information available so far. The aim of our study was to investigate the effect of complete vs. incomplete revascularization in patients up to 70 years of age...
  40. ncbi Laser myocardial revascularization modulates expression of angiogenic, neuronal, and inflammatory cytokines in a porcine model of chronic myocardial ischemia
    Shmuel Fuchs
    Cardiovascular Research Institute, Washington Hospital Center, Washington, DC 20010, USA
    J Card Surg 17:413-24. 2002
    ..Accordingly, we performed a time-course analysis of the expression of angiogenic and neuronal factors following experimental percutaneous TMR...
  41. ncbi Influence of obesity on in-hospital and early mortality and morbidity after myocardial revascularization
    Ariena H Lindhout
    Department of Thoracic and Cardiac Surgery, 414, Heart Center, Nijmegan University Hospital, St Radboud, P O Box 9101, 6500 HB Nijmegen, The Netherlands
    Eur J Cardiothorac Surg 26:535-41. 2004
    ..The aim of this study is to evaluate the in-hospital and early (one year) mortality and morbidity in obese and non-obese patients after a CABG in the UMC St Radboud...
  42. ncbi Emboli formation rather than inflammatory mediators are responsible for increased cerebral water content after conventional and assisted beating-heart myocardial revascularization in a porcine model
    Benjamin Bierbach
    Department of Cardiothoracic and Vascular Surgery, University Hospital Mainz, Mainz, Germany
    Stroke 39:213-9. 2008
    ..A microaxial blood pump can augment cardiac output...
  43. ncbi Survival after coronary revascularization in the elderly
    Michelle M Graham
    Department of Medicine, University of Alberta, Canada
    Circulation 105:2378-84. 2002
    ..We studied survival by prescribed treatment (CABG, PCI, or medical therapy) for patients in 3 age categories: <70 years, 70 to 79 years, and > or =80 years of age...
  44. ncbi [Return to occupational and sexual activity after myocardial revascularization surgery]
    R A Dantas
    Escola de Enfermagem de Ribeirão Preto da Universidade de São Paulo
    Rev Lat Am Enfermagem 9:26-31. 2001
    ..016), and 10 had returned to sexual activity (p = 0.0625). There was change in the subjects' attitudes leading to not returning to work and tendency to not resuming sexual activity in this population...
  45. ncbi Single versus bilateral internal mammary artery for isolated first myocardial revascularization in multivessel disease: long-term clinical results in medically treated diabetic patients
    Antonio Maria Calafiore
    Division of Cardiac Surgery, University Hospital, Turin, Italy
    Ann Thorac Surg 80:888-95. 2005
    ..increases the quality of the results of coronary bypass grafting in medically treated diabetic patients who undergo first myocardial revascularization, when compared with the use of a single left internal mammary artery (LIMA) and SVG.
  46. ncbi Safety and usefulness of composite grafts for total arterial myocardial revascularization: a prospective randomized evaluation
    Claudio Muneretto
    Department of Cardiac Surgery, University of Brescia Medical School, Brescia, Italy
    J Thorac Cardiovasc Surg 125:826-35. 2003
    To evaluate the results of total arterial revascularization with composite grafts compared with the results of conventional coronary surgery, we enrolled 200 consecutive patient undergoing myocardial revascularization.
  47. ncbi Can pulsatile cardiopulmonary bypass prevent perioperative renal dysfunction during myocardial revascularization in elderly patients?
    Pierangela Presta
    Nephrology Unit, Magna Graecia University, Viale Europa, Catanzaro, Italy
    Nephron Clin Pract 111:c229-35. 2009
    ..Since older subjects have a higher risk of acute renal failure, we have extended our study to evaluate the specific impact of pulsatile CPB on the perioperative renal function in elderly patients...
  48. ncbi Respiratory physiotherapy in the pre and postoperative myocardial revascularization surgery
    Simone Cavenaghi
    Hospital de Base de São José do Rio Preto FUNFARME
    Rev Bras Cir Cardiovasc 26:455-61. 2011
    ..In spite of several alternatives for the treatment of the coronary artery disease; the surgery of the myocardial revascularization is an option with proper indications of medium and long-term with good results...
  49. ncbi Incomplete revascularization reduces survival benefit of coronary artery bypass grafting: role of off-pump surgery
    Mats J Synnergren
    Department of Molecular and Clinical Medicine Cardiothoracic Surgery, Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    J Thorac Cardiovasc Surg 136:29-36. 2008
    ..We sought to analyze the influence, if any, of incomplete revascularization and on/off-pump techniques on long-term mortality after coronary artery bypass grafting...
  50. ncbi Advantages of myocardial revascularization after admission for critical limb ischemia in diabetic patients with coronary artery disease: data of a cohort of 564 consecutive patients
    Ezio Faglia
    Diabetology Centre Diabetic Foot Centre, IRCCS Multimedica, Sesto San Giovanni, Italy
    J Cardiovasc Med (Hagerstown) 9:1030-6. 2008
    To evaluate the survival benefit from myocardial revascularization in diabetic patients with critical limb ischemia and coronary artery disease (CAD) in a consecutive series of 564 diabetic patients hospitalized from 1999 to 2003 and ..
  51. ncbi Surgical myocardial revascularization versus percutaneous coronary intervention with drug-eluting stents in octogenarian patients
    Yanai Ben-Gal
    Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Heart Surg Forum 15:E204-9. 2012
    ..Our goal was to compare the clinical outcomes of octogenarian (or older) patients who are referred for either surgical or percutaneous coronary revascularization...
  52. ncbi Ischemic preconditioning suppresses ventricular tachyarrhythmias after myocardial revascularization
    Zhong Kai Wu
    Division of Cardiac Surgery, Department of Surgery, Tampere University Hospital, Tampere, Finland
    Circulation 106:3091-6. 2002
    ..Ischemic preconditioning (IP) has been proved effective in reducing ischemia reperfusion arrhythmia in animals and humans. Whether IP is effective in suppressing postoperative VF/VT in patients with CABG has not been studied...
  53. ncbi Current status and clinical applications of cardiac multidetector computed tomography
    David A Halon
    Department of Cardiovascular Medicine, Lady Davis Carmel Medical Center, Haifa, Israel
    Cardiology 109:73-84. 2008
    ..MDCT is expected to become an integral part of our diagnostic armamentarium in the cardiac patient...
  54. ncbi Temporal trends in the use of percutaneous coronary intervention and coronary artery bypass surgery in New York State and Ontario
    Dennis T Ko
    Institute for Clinical Evaluative Sciences, Schulich Heart Centre, Sunnybrook Health Sciences Centre, Department of Medicine, University of Toronto, Ontario, Canada
    Circulation 121:2635-44. 2010
    ..Although New York State (NYS) historically has had twice as many coronary revascularizations performed as Ontario, the relative evolution of coronary revascularization patterns in both jurisdictions over time is unknown...
  55. ncbi Functional renal outcome in on-pump and off-pump coronary revascularization: a propensity-based analysis
    Arjuna Weerasinghe
    Department of Cardiothoracic Surgery, St Mary s Hospital, London, United Kingdom
    Ann Thorac Surg 79:1577-83. 2005
    ..Renal adverse outcome was defined as minor (20% increase in serum creatinine from preoperative) or major (composite end point of postoperative serum creatinine >200 mumol/L or postoperative mechanical renal support)...
  56. ncbi Transplantation of the free gastroepiploic artery graft for myocardial revascularization: long-term clinical and angiographic results
    Tadahito Eda
    Department of Cardiovascular Surgery, Aichi Cardiovascular and Respiratory Center, Aichi, Japan
    Ann Thorac Surg 85:880-4. 2008
    ..We here assess the clinical result and the angiographic patency of the free GEA graft in our method in the late postoperative period...
  57. ncbi Current management of non-ST-segment-elevation acute coronary syndrome: reconciling the results of randomized controlled trials
    Abhiram Prasad
    Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA
    Eur Heart J 24:1544-53. 2003
    ..The choice of one approach over another is guided largely by local practice patterns and the availability of invasive facilities...
  58. ncbi Myocardial revascularization with radial and mammary arteries: initial and mid-term results
    E E Weinschelbaum
    Department of Cardiovascular Surgery, Institute of Cardiology and Cardiovascular Surgery, Favaloro Foundation, Buenos Aires, Argentina
    Ann Thorac Surg 70:1378-83. 2000
    ..We analyzed the in-hospital and midterm results in patients undergoing coronary artery bypass surgery in whom a combination of arterial grafts was used, including radial artery and one or both internal mammary arteries...
  59. ncbi 'No touch' techniques for porcelain ascending aorta: comparison between cardiopulmonary bypass with femoral artery cannulation and off-pump myocardial revascularization
    Oren Lev-Ran
    Department of Cardiothoracic Surgery, Tel Aviv Sourasky Medical Center, Tel Aviv, Sackler Faculty of Medicine, Tel Aviv University, Israel
    J Card Surg 17:370-6. 2002
    ..Off-pump coronary artery bypass grafting (OPCAB) confers the benefits of avoiding aortic cannulation and clamping, and may therefore attenuate this risk...
  60. ncbi [Off-pump coronary artery bypass grafting in patients over the age of seventy]
    Song Xue
    Department of Cardiovascular Surgery, Shanghai First People s Hospital, Shanghai 200080, China
    Zhonghua Wai Ke Za Zhi 42:661-3. 2004
    ..To discuss the choice of surgical methods and the safety and efficacy of off-pump coronary artery bypass grafting (OPCAB) in elderly patients...
  61. ncbi Medical therapy versus myocardial revascularization in chronic coronary syndrome and stable angina
    Prakash C Deedwania
    Division of Cardiology, Department of Medicine, Veterans Affairs Central California Health Care System, University of California, San Francisco, School of Medicine, Fresno, USA
    Am J Med 124:681-8. 2011
    ..angina include antianginal drugs: nitrates, beta-blockers, calcium channel blockers, ranolazine, and myocardial revascularization. Recent trials have shown that although revascularization is slightly better in controlling symptoms, ..
  62. ncbi Midterm outcomes of myocardial revascularization in children
    Nicola Viola
    The Labatt Family Heart Centre, The Hospital for Sick Children and the University of Toronto, Ontario, Canada
    J Thorac Cardiovasc Surg 139:333-8. 2010
    ..Pediatric coronary artery bypass grafting is uncommon. Small target vessels and appropriate conduit choice are the main technical challenges...
  63. ncbi Joint ESC/EACTS guidelines on myocardial revascularization
    Philippe Kolh
    Cardiovascular Surgery Department, University Hospital, CHU, ULg of Liege, Liege, Belgium
    J Cardiovasc Med (Hagerstown) 12:264-7. 2011
    The Guidelines for Myocardial Revascularization of the European Society of Cardiology (ESC) and European Association for Cardio-Thoracic Surgery (EACTS) are the very first reported consensus document, by a writing committee balanced ..
  64. pmc Arterial myocardial revascularization using bilateral radial artery 17 years after right pneumonectomy
    Nevzat Erdil
    Department of Cardiovascular Surgery, Inonu University, Turgut Ozal Medical Center, 44315 Malatya, Turkey
    Tex Heart Inst J 31:96-8. 2004
    We report the case of a 51-year-old man who underwent arterial myocardial revascularization with the use of bilateral radial arteries, 17 years after undergoing a right pneumonectomy...
  65. ncbi Off-pump coronary artery bypass surgery technique for total arterial myocardial revascularization: a prospective randomized study
    Claudio Muneretto
    Division of Cardiac Surgery, University of Brescia Medical School, Brescia, Italy
    Ann Thorac Surg 76:778-82; discussion 783. 2003
    We investigated whether off-pump coronary artery bypass (OPCAB) surgery should be the procedure of choice in total arterial myocardial revascularization with composite grafts.
  66. ncbi Endothelin-1 and acute myocardial infarction: a no-reflow mediator after successful percutaneous myocardial revascularization
    Giampaolo Niccoli
    Institute of Cardiology, Catholic University of the Sacred Heart, 00168 Rome, Italy
    Eur Heart J 27:1793-8. 2006
    ..We aimed to investigate the relationship between systemic ET-1 plasma levels and no-reflow in a group of AMI patients treated by primary PCI...
  67. ncbi All-cause readmission and repeat revascularization after percutaneous coronary intervention in a cohort of medicare patients
    Jeptha P Curtis
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut, USA
    J Am Coll Cardiol 54:903-7. 2009
    ..The purpose of this study was to report on the all-cause readmission and repeat revascularization rates after percutaneous coronary intervention (PCI)...
  68. pmc The association between socioeconomic position, use of revascularization procedures and five-year survival after recovery from acute myocardial infarction
    Maria Rosvall
    Social Epidemiology, Department of Clinical Sciences, Malmo University Hospital, Lund University, Malmo, Sweden
    BMC Public Health 8:44. 2008
    ..In this Swedish nation-wide longitudinal study we wanted to evaluate long-term survival after AMI in relation to socioeconomic position (SEP) and use of revascularization...
  69. ncbi The effects of intermittent positive pressure and incentive spirometry in the postoperative of myocardial revascularization
    Walmir Romanini
    Pontificia Universidade Catolica do Parana, Curitiba, PR, Brasil
    Arq Bras Cardiol 89:94-9, 105-10. 2007
    ..Pulmonary complications are important causes of morbidity and fatalities among patients subject to cardiac surgery. The respiratory physiotherapy has been aiding in the recovery of these patient ones...
  70. ncbi Inflammation and long-term mortality after non-ST elevation acute coronary syndrome treated with a very early invasive strategy in 1042 consecutive patients
    Christian Mueller
    Herz Zentrum Bad Krozingen, Germany
    Circulation 105:1412-5. 2002
    ..This study sought to evaluate the predictive value of C-reactive protein (CRP) on long-term mortality in non-ST-elevation acute coronary syndromes (NSTACS) that were treated with a very early aggressive revascularization strategy...
  71. ncbi A score proposal to evaluate surgical risk in patients submitted to myocardial revascularization surgery
    Michel Pereira Cadore
    Unidade de Tratamento Intensivo Cardiovascular, Pós Operatório de Cirurgia Cardíaca, Hospital São Lucas da PUC RS, Porto Alegre, Rio Grande do Sul, Brazil
    Rev Bras Cir Cardiovasc 25:447-56. 2010
    Scores to predict surgical risk in patients submitted to myocardial revascularization surgery are broadly used.
  72. ncbi Effects of milrinone versus epinephrine on left ventricular relaxation after cardiopulmonary bypass following myocardial revascularization: assessment by color m-mode and tissue Doppler
    Emilio B Lobato
    Department of Anesthesiology, University of Florida College of Medicine and Veterans Affairs Medical Center, Gainesville, 32610, USA
    J Cardiothorac Vasc Anesth 19:334-9. 2005
    ..The purpose of this study was to evaluate the left ventricular lusitropic effects of epinephrine versus milrinone after cardiopulmonary bypass...
  73. ncbi Patients with hibernating myocardium show altered left ventricular volumes and shape, which revert after revascularization: evidence that dyssynergy might directly induce cardiac remodeling
    Erberto Carluccio
    Department of Cardiology, University of Perugia School of Medicine, Perugia, Italy
    J Am Coll Cardiol 47:969-77. 2006
    ..e., in the absence of transmural necrosis) and whether this phenomenon is potentially reversible after contractile recovery...
  74. ncbi Ministernotomy in myocardial revascularization preserves postoperative pulmonary function
    Solange Guizilini
    Escola Paulista de Medicina, Universidade Federal de Sao Paulo, Sao Paulo, SP, Brasil
    Arq Bras Cardiol 95:587-93. 2010
    ..In coronary artery bypass graft (CABG) surgery, the need to perform a midsternotomy has been considered a factor for the decrease in postoperative pulmonary function...
  75. ncbi Increasing resources effected equity in access to revascularizations for patients with diabetes
    Tuulikki Vehko
    National Institute for Health and Welfare THL, Helsinki, Finland
    Scand Cardiovasc J 44:237-44. 2010
    ....
  76. ncbi Neovascularization of ischemic myocardium by human bone-marrow-derived angioblasts prevents cardiomyocyte apoptosis, reduces remodeling and improves cardiac function
    A A Kocher
    Department of Surgery, Columbia University, New York, New York, USA
    Nat Med 7:430-6. 2001
    ....
  77. ncbi Guidelines for percutaneous coronary interventions. The Task Force for Percutaneous Coronary Interventions of the European Society of Cardiology
    Sigmund Silber
    Kardiologische Praxis und Praxisklinik, Munchen, Germany
    Eur Heart J 26:804-47. 2005
    ....
  78. ncbi Acute coronary care in the elderly, part II: ST-segment-elevation myocardial infarction: a scientific statement for healthcare professionals from the American Heart Association Council on Clinical Cardiology: in collaboration with the Society of Geriatric
    Karen P Alexander
    Duke University Medical Center, USA
    Circulation 115:2570-89. 2007
    ....
  79. pmc Angiotensin-converting-enzyme inhibition in stable coronary artery disease
    Eugene Braunwald
    Harvard Medical School and Brigham and Women s Hospital, Boston, MA 02115, USA
    N Engl J Med 351:2058-68. 2004
    ..ACE inhibitors have also been shown to reduce atherosclerotic complications in patients who have vascular disease without heart failure...
  80. ncbi Effects of pretreatment with clopidogrel and aspirin followed by long-term therapy in patients undergoing percutaneous coronary intervention: the PCI-CURE study
    S R Mehta
    Division of Cardiology, the Population Health Research Institute and the Canadian Cardiovascular Collaboration Project Office, McMaster University, Hamilton, Canada
    Lancet 358:527-33. 2001
    ..We aimed to find out whether, in addition to aspirin, pretreatment with clopidogrel followed by long-term therapy after PCI is superior to a strategy of no pretreatment and short-term therapy for only 4 weeks after PCI...
  81. pmc Trends in coronary artery revascularisation procedures in Western Australia, 1980-2001
    M S T Hobbs
    School of Population Health, University of Western Australia, 35 Stirling Highway, Crawley WA 6009, Australia
    Heart 90:1036-41. 2004
    ..To describe trends in the use of coronary artery revascularisation procedures (CARPs) and to determine whether or when CARP rates will stabilise...
  82. ncbi Tranexamic acid reduces bleeding and the need for blood transfusion in primary myocardial revascularization
    Deeb Zabeeda
    Department of Anesthesia, The Edith Wolfson Medical Center, Holon, Israel
    Ann Thorac Surg 74:733-8. 2002
    ..The objective of this study was to study the effect of low-dose tranexamic acid (TA) on postoperative bleeding and coagulation variables after coronary artery bypass grafting operation...
  83. ncbi Time course of functional recovery of stunned and hibernating segments after surgical revascularization
    J J Bax
    Department of Cardiology, Leiden University Medical Center, Leiden
    Circulation 104:I314-8. 2001
    ..Accordingly, the time courses of functional recovery in hibernating and stunned myocardium were compared...
  84. ncbi EuroSCORE as predictor of in-hospital mortality after percutaneous coronary intervention
    E Romagnoli
    Institute of Cardiology, Universita Cattolica del Sacro Cuore, Rome, Italy
    Heart 95:43-8. 2009
    ..Thus, we sought to assess the European System for Cardiac Operative Risk Evaluation (EuroSCORE) validity to predict in-hospital mortality after percutaneous coronary intervention (PCI)...
  85. ncbi Usefulness of 64-slice cardiac computed tomographic angiography for diagnosing acute coronary syndromes and predicting clinical outcome in emergency department patients with chest pain of uncertain origin
    Ronen Rubinshtein
    Department of Cardiovascular Medicine, Lady Davis Carmel Medical Center and the Ruth and Bruce Rappaport School of Medicine, Technion Israel Institute of Technology, Haifa, Israel
    Circulation 115:1762-8. 2007
    ....
  86. ncbi Troponin I and lactate from coronary sinus predict cardiac complications after myocardial revascularization
    Francesco Onorati
    Cardiac Surgery Unit, Magna Graecia University, Catanzaro, Italy
    Ann Thorac Surg 83:1016-23. 2007
    Postoperative troponin I and lactate elevation are related to cardiac complications after myocardial revascularization. We sought to evaluate earlier predictive value for acute myocardial infarction (AMI) and myocardial damage of troponin ..
  87. pmc Short-term and long-term outcomes in 133,429 emergency patients admitted with angina or myocardial infarction in Scotland, 1990-2000: population-based cohort study
    S Capewell
    Department of Public Health, University of Liverpool, Liverpool, UK
    Heart 92:1563-70. 2006
    ..To analyse short- and long-term outcomes and prognostic factors in a large population-based cohort of unselected patients with a first emergency admission for suspected acute coronary syndrome between 1990 and 2000 in Scotland...
  88. ncbi [Differences between women's and men's access to interventional cardiovascular procedures at public hospitals in Andalusia (Spain)]
    María J Aguado-Romeo
    Agencia de Evaluación de Tecnología Sanitaria, Consejeria de Salud, Junta de Andalucia, Sevilla, Espana
    Rev Esp Cardiol 59:785-93. 2006
    ..The aim of this study was to determine whether there are differences between women's and men's access to coronary revascularization procedures for acute coronary syndrome in Andalusia, Spain...
  89. ncbi Coronary CT angiography and myocardial perfusion imaging to detect flow-limiting stenoses: a potential gatekeeper for coronary revascularization?
    Oliver Gaemperli
    Cardiac Imaging, University Hospital Zurich, Ramistrasse 100, CH 8091 Zurich, Switzerland
    Eur Heart J 30:2921-9. 2009
    ....
  90. ncbi Clinical and angiographic risk assessment in patients with left main stem lesions
    Scot Garg
    Department of Interventional Cardiology, Erasmus Medical Center, Rotterdam, The Netherlands
    JACC Cardiovasc Interv 3:891-901. 2010
    ..This paper reviews contemporary and newly proposed risk models for patients undergoing left main stem revascularization...
  91. ncbi Outcomes in patients with de novo left main disease treated with either percutaneous coronary intervention using paclitaxel-eluting stents or coronary artery bypass graft treatment in the Synergy Between Percutaneous Coronary Intervention with TAXUS and C
    Marie Claude Morice
    Institut Hospitalier Jacques Cartier, 6 avenue du Noyer Lambert, Massy, France
    Circulation 121:2645-53. 2010
    ....
  92. ncbi Nonstress delayed-enhancement magnetic resonance imaging of the myocardium predicts improvement of function after revascularization for chronic ischemic heart disease with left ventricular dysfunction
    Paulo R Schvartzman
    Department of Radiology Section of Cardiovascular Imaging, Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA
    Am Heart J 146:535-41. 2003
    ..This investigation assessed the use of DE-MRI for predicting functional improvement after coronary artery bypass grafting (CABG) in patients with CIHD and significant LV dysfunction...
  93. ncbi Nonrandomized comparison of coronary artery bypass surgery and percutaneous coronary intervention for the treatment of unprotected left main coronary artery disease in octogenarians
    Josep Rodes-Cabau
    Department of Cardiology and Cardiac Surgery, Quebec Heart Institute, Laval Hospital, Quebec, Canada
    Circulation 118:2374-81. 2008
    ....
  94. ncbi The role of ascorbic acid in the prevention of atrial fibrillation after elective on-pump myocardial revascularization surgery: a single-center experience--a pilot study
    Pavlos Papoulidis
    Department of Cardiothoracic Surgery, General Hospital G Papanikolaou, Exohi, 57010 Thessaloniki, Greece
    Interact Cardiovasc Thorac Surg 12:121-4. 2011
    ..5±2.8 days vs. 6.7±1.9, P=0.034). Supplementation of vitamin C reduces the incidence of postCABG AF, and decreases the time needed for rhythm restoration and length of hospital stay...
  95. ncbi Current state of surgical myocardial revascularization
    Frank W Sellke
    Department of Cardiothoracic Surgery, Alpert Medical School of Brown University, Providence, RI, USA
    Circ J 74:1031-7. 2010
    ..This review article provides a brief historical perspective on the procedure, and examines the current state of modern variations including off-pump, limited-access, and robotic-assisted CABG...
  96. ncbi Early and midterm results after coronary artery bypass grafting with and without cardiopulmonary bypass: which patient population benefits the most?
    Tobias Deuse
    Department of Cardiac Surgery, Grosshadern Medical Center, Ludwig Maximilians University, Munich, Germany
    Heart Surg Forum 6:77-83. 2003
    ..We present our early and midterm results with off-pump coronary artery bypass grafting (OPCAB) on the beating heart and with conventional coronary artery bypass grafting (CABG) and compare patient outcomes for both procedures...
  97. ncbi Socioeconomic inequities in invasive cardiac procedures after first myocardial infarction in Finland in 1995
    Tiina Hetemaa
    National Research and Development Centre for Welfare and Health STAKES, Outcome and Equity Research, Lintulahdenkuja 4, 00530, Helsinki, Finland
    J Clin Epidemiol 57:301-8. 2004
    ..We examined socioeconomic disparities in coronary procedure rates after first events among hospitalized myocardial infarction (MI) patients...
  98. ncbi Immediate results of right internal thoracic artery and radial artery as the second arterial graft in myocardial revascularization
    Leonardo Augusto Miana
    Cardiovascular Surgery Service of Santa Casade Misericórdia in Juiz de Fora, Juiz de Fora MG
    Rev Bras Cir Cardiovasc 22:60-7. 2007
    We sought to compare early clinical outcomes in patients receiving a right internal thoracic artery or a radial artery as the second arterial graft in myocardial revascularization.
  99. pmc Inequalities in coronary revascularisation during the 1990s: evidence from the British regional heart study
    R W Morris
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London NW3 2PF, UK
    Heart 91:635-40. 2005
    ..To investigate the influence of age and social circumstances on probability of revascularisation among British men...
  100. pmc Degree of risk related to procedures performed in conjunction with surgical myocardial revascularization in octogenarians
    Jose Carlos Rossini Iglezias
    InCor, Hospital das Clinicas, Faculdade de Medicina, Universidade de Sao Paulo, Sao Paulo, SP, Brazil
    Clinics (Sao Paulo) 64:387-92. 2009
    We determined the degree of risk produced by the association of other surgical procedures with surgical myocardial revascularization in octogenarian patients and identified the risk factors that best explain hospital mortality.
  101. ncbi Quality of life after surgical myocardial revascularization, angioplasty or medical treatment
    Myrthes Emy Takiuti
    Instituto do Coracao, Hospital das Clinicas, FM, USP, Sao Paulo, SP, Brazil
    Arq Bras Cardiol 88:537-44. 2007
    ..Although the clinical benefits of coronary interventions seem to be confirmed, their effects on quality of life (QoL) are still scarcely studied...

Research Grants65

  1. Acute Coronary Syndrome Outcomes for Medicare Patients
    SALLY STEARNS; Fiscal Year: 2009
    ..The gold standard therapy for acute coronary syndrome (ACS) is early mechanical myocardial revascularization with either percutaneous intervention with stents (PCIS) or coronary artery bypass grafting (CABG)...
  2. STICHES
    Eric J Velazquez; Fiscal Year: 2013
    DESCRIPTION (provided by applicant): The STICH Myocardial Revascularization Hypothesis completed enrollment of 1212 subjects in whom the responsible physicians were at equipoise regarding the benefits of myocardial revascularization in ..
  3. Molecular regulation of vein graft adapation
    Alan Dardik; Fiscal Year: 2013
    ..Improving results of long-term myocardial revascularization and limb salvage remain critically dependent on understanding the mechanisms of excessive intimal ..
  4. SKELETAL MUSCLE FOR MYOCARDIAL ASSISTANCE
    JOHN MANNION; Fiscal Year: 1993
    ..objectives of this proposed research: the first is to evaluate the potential for an indirect method of myocardial revascularization using chronically electrically stimulated skeletal muscle as a rich source of collateral blood supply; ..
  5. Imaging and Laser Revascularization in Hibernation
    Lynne Johnson; Fiscal Year: 2003
    ..for CABG or PICA are now being considered for new methods of revascularization such as direct myocardial revascularization with laser channels using catheter based approach (DMR)...
  6. IMPROVING OUTCOMES AND QUALITY OF LIFE AFTER CABG
    Mary Charlson; Fiscal Year: 1999
    Surgical myocardial revascularization (CABG) is an effective treatment for triple vessel and left main coronary artery disease used for thousands of patients annually in the United States...
  7. CARDIAC SURGERY AND CEREBROVASCULAR COMPLICATIONS
    TODD TROOST; Fiscal Year: 1993
    ..In patients undergoing myocardial revascularization, Project 1 will determine if careful avoidance of hyperglycemia, which worsens experimental ischemic ..
  8. Vector Identification and Gene Delivery Approach in Pigs
    JUDITH GWATHMEY; Fiscal Year: 2007
    ..Despite advances in traditional approaches to its treatment, including pharmacological management, myocardial revascularization, mechanical assist devices, and transplantation, heart failure remains a leading cause of death ..
  9. Vector Identification and Gene Delivery Approach in Pigs
    JUDITH GWATHMEY; Fiscal Year: 2005
    ..Despite advances in traditional approaches to its treatment, including pharmacologic management, myocardial revascularization, mechanical assist devices, and transplantation, CHF remains a leading cause of death worldwide...
  10. NONINVASIVE PROTON BEAM MYOCARDIAL REVASCULARIZATION
    Keith March; Fiscal Year: 2000
    ..This exploratory study will examine the feasibility of using external proton radiation to induce myocardial revascularization.
  11. TOSCA-2 An Angiographic Substudy of the Occluded Arter*
    Vladimir Dzavik; Fiscal Year: 2004
    ..The Data Coordinating Center (DCC) is the Maryland Medical Research Institute, the DCC of OAT. The An2iogiraphic Core Laboratory is at the University of British Columbia. ..
  12. Safer Antithrombotic Therapy for Elderly ACS Patients
    Eric Peterson; Fiscal Year: 2006
    ..Finally, we will use established relations with professional societies and the VHA to widely disseminate our study's major findings. ..
  13. Genetic Predictors of Outcome in Acute MI
    Marc Sabatine; Fiscal Year: 2005
    ..Genomic control will be employed to detect and control for population stratification. Interaction terms will be incorporated into regression models to explore gene-environment and pharmacogenomic interactions. ..
  14. Impact of CHD Risk Perception on Health Behaviors and O*
    Janice Barnhart; Fiscal Year: 2005
    ....
  15. Retrograde In Situ Isolated Cardiac Gene Delivery
    Charles Bridges; Fiscal Year: 2004
    ..Further development of this approach may ultimately lead to the development of clinically relevant techniques of therapeutic cardiac gene delivery for the treatment of heart failure of diverse etiologies. ..
  16. Inflammation, Procoagulation, and Plaque Vulnerability
    Burton Sobel; Fiscal Year: 2005
    ..abstract_text> ..
  17. Evaluating reasons for variations in LDL levels
    P Ho; Fiscal Year: 2003
    ..abstract_text> ..
  18. Whole Genome Association Study of Migraine in Women
    ROBERT YUK LUNG ZEE; Fiscal Year: 2010
    ..Thus, we request funding to study the genomic of migraine using a whole genome approach and to evaluate gene-environment interactions. ..
  19. Neighborhood Disparities and Access to Cardiac Care
    Jing Fang; Fiscal Year: 2003
    ..This would be important for policy to eliminate the health disparity. ..
  20. Novel Imaging to Predict Cardiovascular Events in Diabetes
    Zahi A Fayad; Fiscal Year: 2010
    ..It is our expectation that our data will be utilized to evaluate and improve existent treatment and develop effective new therapies to decrease the burden of atherosclerotic disease in diabetes. ..
  21. BARI II - FIBRINOLYSIS AND COAGULATION CORE
    Burton Sobel; Fiscal Year: 2006
    ..The investigators further expect that this collaborative effort will translate into a new practical clinical paradigm that will be used for treatment of Type II diabetic patients. ..
  22. Restless Legs Syndrome, Cardiovascular Risk Factors, and Cardiovascular Events
    Tobias Kurth; Fiscal Year: 2010
    ..Thus, this grant proposal request funding to study the association between RLS, CVD risk factors as well as CVD events. ..
  23. Mechanism of Myocardial Angiogenesis in Transgenic/Knockout Animals
    Nilanjana Maulik; Fiscal Year: 2010
    ..This proposal will provide and will identify important new insights into the cellular and molecular mechanisms of the cardioprotection provided by VEGF signaling through important candidate genes. ..
  24. Family Cardiac Caregiver Investigation to Evaluate Outcomes (FIT-O)
    Lori J Mosca; Fiscal Year: 2010
    ..Improved adherence to evidence-based preventive therapies could have a substantial public health benefit. ..
  25. Retinopathy in Chronic Renal Insufficiency
    Juan E Grunwald; Fiscal Year: 2010
    ....
  26. Activating Consumers to Exercise in Community Psychiatry Through Peer Support.
    Gail Daumit; Fiscal Year: 2008
    ..This study will provide important data for future work to reduce cardiovascular risk and improve health in persons with SMI. [unreadable] [unreadable] [unreadable]..
  27. Cardiac care in specialty and general hospitals
    Peter M Cram; Fiscal Year: 2010
    ..Together these analyses will provide much needed information on the relative quality of care provided by specialty cardiac hospitals to policy makers, payors, providers and patients. ..
  28. The significance of racial segregation for CV disease
    Mary Vaughan Sarrazin; Fiscal Year: 2007
    ..The knowledge gained from this study about the significance of segregation as a determinant of racial disparity will be essential for designing effective strategies for eliminating disparities. [unreadable] [unreadable] [unreadable]..
  29. New Cardiac Surgery Programs: Patients, Outcomes, Access
    FRANCES LUCAS; Fiscal Year: 2008
    ..procedures or result in an overall increase in the population-based rates of care, including CABG and total revascularization (either CABG or percutaneous coronary interventions) as additional capacity is brought online? ..
  30. Genetics Myocardial Adverse Outcomes/Graft Failure-CABG
    Mihai Podgoreanu; Fiscal Year: 2008
    ....
  31. Angiogenesis in a model of diabetes and endothelial dysfunction
    Frank Sellke; Fiscal Year: 2009
    ..We hope that the results of these studies will bring important insights about the mechanisms inhibiting chronic ischemia induced endogenous angiogenesis and the response to exogenous factors in more relevant animal models of diabetes. ..
  32. Pain Medication Use & Risk Factors for Opioid Dependence
    Daniel Solomon; Fiscal Year: 2004
    ..Our goal is to use the results of the proposed research to inform a future intervention to improve opioid prescribing within this large pharmacy benefits program. ..
  33. Randomized Control Trial of Mifepristone for Fibroids
    Kevin Fiscella; Fiscal Year: 2004
    ..The study may also offer valuable insight into a mechanism by which mifepristone reduces fibroid size. ..
  34. OPIOID HIBERNATION FACTORS FOR MYOCARDIAL PROTECTION
    Steven Bolling; Fiscal Year: 2002
    ..The ability of the delta opioids to effect myocardial protection suggests that the use of these molecules may be valuable in many clinical scenarios resulting in ischemia. ..
  35. MAGNETIC RESONANCE CORONARY ANGIOGRAPHY
    John Oshinski; Fiscal Year: 2001
    ....
  36. Bone Marrow Angioblasts For Cardiac Regeneration
    Silviu Itescu; Fiscal Year: 2004
    ....
  37. Impact of Certificate of Need on the Use of Revascularization for AMI
    Mary Vaughan Sarrazin; Fiscal Year: 2006
    ..g., revascularization, mortality) and Cox regression with stratification for time-to-event outcomes (e.g., time to readmission). [unreadable] [unreadable]..
  38. Choroidal circulation in age related macular degeneration
    Juan Grunwald; Fiscal Year: 2008
    ..In addition, the knowledge gained through this investigation could also help in the identification of patients at risk of developing choroidal neovascularization, thus enabling earlier treatment. [unreadable] [unreadable] [unreadable]..
  39. OCULAR HEMODYNAMICS IN GLAUCOMA
    Juan Grunwald; Fiscal Year: 2001
    ..If hemodynamic abnormalities are present, then attention can be focused on altering the optic nerve circulation as a means of treating glaucoma. ..
  40. OBESITY IN BLACK WOMEN
    Jeanine Albu; Fiscal Year: 2001
    ....
  41. THROMBOTIC, INFLAMMATORY & GENE MARKERS OF CVD IN WOMEN
    Paul Ridker; Fiscal Year: 2002
    ....
  42. Randomized Controlled Testing of Osteoporosis Education
    Daniel Solomon; Fiscal Year: 2006
    ..A multi-disciplinary Training Advisory Board will review the applicants progress regularly to ensure that the proposed training goals are met. ..
  43. HEART RATE RECOVERY AND MORTALITY
    Michael Lauer; Fiscal Year: 2002
    ..All the data needed for this project are already electronically available; that fact, along with the work already done, lends confidence to the feasibility of this project. ..
  44. Transforming PCI Informed Consent into an Evidence-based Decision-making Tool
    John A Spertus; Fiscal Year: 2010
    ..We will then estimate the cost-savings associated with more rational BAT use to test the hypothesis that PRISM will improve the cost-effectiveness of PCI. ..
  45. OBSERVATIONAL COHORT STUDY OF SODIUM, WEIGHT AND CVD
    Nancy Cook; Fiscal Year: 2003
    ..This cohort provides a unique resource to address the impact in a normotensive population of salt restriction and weight change on subsequent cardiovascular events. ..
  46. MENTAL & SOMATIC ILLNESS: NEEDS, SERVICES, AND OUTCOMES
    Gail Daumit; Fiscal Year: 2004
    ..Daumit the experience and tools she needs to develop into an independent clinician research in the epidemiology and health services research of mental disorders. ..
  47. The Effectiveness of Treatment for Adult Periodontitis
    Philippe Hujoel; Fiscal Year: 2006
    ..This information can help determine in what area of periodontal research definitive clinical trials may offer the greatest contribution. ..
  48. Bone Marrow Angioblasts for Myocardial Vasculogenesis
    Silviu Itescu; Fiscal Year: 2006
    ..abstract_text> ..
  49. Modified Late Infarct Reperfusion to Prevent Post MI CHF
    Robert Gorman; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  50. Mechanisms of Cardioprotection
    Roberto Bolli; Fiscal Year: 2007
    ....
  51. MESA Family Study
    Karol Watson; Fiscal Year: 2007
    ..abstract_text> ..
  52. Intramyocellular Lipid: Effects of Race and Diet
    Jeanine Albu; Fiscal Year: 2007
    ..In this regard these studies may help to identify mechanisms for race-ethnic disparities in the incidence of type 2 diabetes mellitus and therefore respond to the NIH PA number 04-074. [unreadable] [unreadable] [unreadable]..
  53. Cardiovascular Development and Disease in the Young
    Michael Rosen; Fiscal Year: 2008
    ..abstract_text> ..
  54. Mechanistic Determinants of Pacing-induced Cardiac Memory
    Michael R Rosen; Fiscal Year: 2010
    ..Rather than being reductionist, the approach attempts to synthesize information so that we can better comprehend and impact on a clinically important problem. ..
  55. LONGITUDINAL METHODS IN CANCER RESEARCH
    Therese Stukel; Fiscal Year: 2002
    ..The methods we propose will circumvent many of the above technical difficulties and would not require either special software or high performance computer workstations. ..
  56. SHOCK TRIAL: LONG-TERM SURVIVAL AND STATISTICAL SUPPORT
    Lynn Sleeper; Fiscal Year: 2004
    ..abstract_text> ..
  57. CHD Incidence: Depression & Inflammation Risk
    Karina Davidson; Fiscal Year: 2006
    ..We propose to assay plasma samples for CRP, IL-6 and ICAM-1 and then to statistically model the associations among depression, inflammation and CHD incidence. ..
  58. SECONDARY PREVENTION TRIAL OF VENOUS THROMBOSIS
    Paul Ridker; Fiscal Year: 2002
    ....
  59. Utility of a New Database to Study Drug Safety during Pregnancy
    SOKO SETOGUCHI IWATA; Fiscal Year: 2008
    ..This database based on large population-based follow-up data with linkable clinical birth data has the potential to enhance the safety of prescription drug use in pregnant women and their children. [unreadable] [unreadable] [unreadable]..
  60. Assisted Patient-Selection for Thrombolytics in Stroke
    David Kent; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  61. Improving Treatment of Newly Diagnosed Osteoporosis
    Peter Cram; Fiscal Year: 2009
    ..Finally, this work will serve as a model for examining the barriers to and improving treatment of other chronic diseases identified through screening. ..