Genomes and Genes
cardiac surgical procedures
Summary: Surgery performed on the heart.
Articles from Journal RESEARCH
Articles from Journal RESEARCH1
Publications316 found, 100 shown here
- Neutrophil gelatinase-associated lipocalin (NGAL) as a biomarker for acute renal injury after cardiac surgeryJaya Mishra
Division of Nephrology and Hypertension, Cincinnati Children s Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH 45229 3039, USA
Lancet 365:1231-8. 2005..We tested the hypothesis that neutrophil gelatinase-associated lipocalin (NGAL) is an early biomarker for ischaemic renal injury after cardiopulmonary bypass...
- Acute kidney injury associated with cardiac surgeryMitchell H Rosner
Division of Nephrology, Department of Internal Medicine, University of Virginia Health System, Box 800133, Charlottesville, VA 22908, USA
Clin J Am Soc Nephrol 1:19-32. 2006..Several compounds such as atrial natriuretic peptide and N-acetylcysteine have shown promise, but large-scale trials are needed...
- European system for cardiac operative risk evaluation (EuroSCORE)S A Nashef
Papworth Hospital, Cambridge, UK
Eur J Cardiothorac Surg 16:9-13. 1999..To construct a scoring system for the prediction of early mortality in cardiac surgical patients in Europe on the basis of objective risk factors...
- Risk factors and outcome in European cardiac surgery: analysis of the EuroSCORE multinational database of 19030 patientsF Roques
Service de chirurgie cardiovasculaire, CHU de Fort de France, Martinique, France
Eur J Cardiothorac Surg 15:816-22; discussion 822-3. 1999..To assess risk factors for mortality in cardiac surgical adult patients as part of a study to develop a European System for Cardiac Operative Risk Evaluation (EuroSCORE)...
- Transfusion requirements after cardiac surgery: the TRACS randomized controlled trialLudhmila A Hajjar
Surgical Intensive Care Unit and Department of Anesthesiology, Heart Institute InCor, Hospital das Clinicas da Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo, Brazil
JAMA 304:1559-67. 2010....
- The development of cardiac surgery in West Africa--the case of GhanaFrank Edwin
National Cardiothoracic Center, Korle Bu Teaching Hospital, P O Box KB 846, Accra, Ghana
Pan Afr Med J 9:15. 2011..It aims to dispel the notion that there are no major active cardiothoracic centers in the West African sub-region...
- Serum interleukin-6 and interleukin-8 are early biomarkers of acute kidney injury and predict prolonged mechanical ventilation in children undergoing cardiac surgery: a case-control studyKathleen D Liu
Divisions of Nephrology and Critical Care Medicine, Departments of Medicine and Anesthesia, University of California, San Francisco, San Francisco, CA, USA
Crit Care 13:R104. 2009..The purpose of this study was to test the role of serum cytokines as biomarkers for AKI and prolonged mechanical ventilation...
- Risk factors for perioperative acute kidney injury after adult cardiac surgery: role of perioperative managementAlessandro Parolari
Department of Cardiovascular Sciences, Unit for Clinical Research in Atherothrombosis, Centro Cardiologico Monzino IRCCS, University of Milan, Milan, Italy
Ann Thorac Surg 93:584-91. 2012..Our aim was to assess the risk factors for postoperative AKI and whether the addition of perioperative management variables can improve AKI prediction...
- Predicting acute kidney injury after cardiac surgery: a systematic reviewSarah C Huen
Department of Medicine, Section of Nephrology, Yale University School of Medicine, New Haven, Connecticut, USA
Ann Thorac Surg 93:337-47. 2012..Standardizing risk factor and AKI definitions will facilitate the development and validation of risk models predicting AKI...
- Inflammatory response to cardiopulmonary bypassJerrold H Levy
Department of Anesthesiology, Emory University School of Medicine, Division of Cardiothoracic Anesthesiology and Critical Care, Emory Healthcare, Atlanta, Georgia, USA
Ann Thorac Surg 75:S715-20. 2003..Novel agents are under investigation to further improve outcomes in cardiac surgical patients...
- RIFLE criteria for cardiac surgery-associated acute kidney injury: risk factors and outcomesAugusto D'Onofrio
Division of Cardiac Surgery, San Bortolo Hospital, Vicenza, Italy
Congest Heart Fail 16:S32-6. 2010..In conclusion, patients who develop CSA-AKI have a higher preoperative risk profile, more complex surgery, and worse clinical outcomes...
- Improvements in health-related quality of life before and after isolated cardiac operationsKathleen L Grady
Division of Cardiac Surgery, Bluhm Cardiovascular Institute of Northwestern Memorial Hospital, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA
Ann Thorac Surg 91:777-83. 2011....
- Prediction models for prolonged intensive care unit stay after cardiac surgery: systematic review and validation studyRoelof G A Ettema
University of Applied Science Utrecht, Faculty of Health Care, Bolognalaan 101 3584 CJ Utrecht, Netherlands
Circulation 122:682-9, 7 p following p 689. 2010..However, no extensive quantitative validation of these models has yet been conducted. This study sought to identify and validate existing prediction models for prolonged ICU length of stay after cardiac surgery...
- Relationship of a common polymorphism of the glucocorticoid receptor gene to traumatic memories and posttraumatic stress disorder in patients after intensive care therapyDaniela Hauer
Departments of Anaesthesiology, Ludwig Maximilians University, Munich, Germany
Crit Care Med 39:643-50. 2011....
- Cardiac surgical experience in northern NigeriaJ Nwiloh
Section of Cardiothoracic Surgery, St Joseph s Hospital, Atlanta, GA, USA
Cardiovasc J Afr 23:432-4. 2012..This preliminary result has further stimulated the interest of all stakeholders on the urgency to establish open-heart surgery as part of the armamentarium to combat the ravages of heart diseases in northern Nigeria...
- Treatment of gram-positive deep sternal wound infections in cardiac surgery--experiences with daptomycinAron F Popov
Department of Thoracic Cardiovascular Surgery, University of Gottingen, Germany
J Cardiothorac Surg 6:112. 2011..Based on these observations, daptomycin may offer a new treatment option for expediting surgical management of DSWI after cardiac surgery...
- Acute kidney injury after cardiac surgery: focus on modifiable risk factorsKeyvan Karkouti
Department of Anesthesia and Health Policy, Management, and Evaluation, Toronto General Hospital, University of Toronto, 200 Elizabeth St, EN 3 402, Toronto, Ontario, Canada M5G 2C4
Circulation 119:495-502. 2009..Lacking effective therapies, risk factor modification may offer a means of preventing this complication. The objective of the present study was to identify and determine the prognostic importance of such risk factors...
- Wound complications after median sternotomy: a single-centre studyClaudia Heilmann
Department of Cardiovascular Surgery, Heart Center Freiburg University, Freiburg, Germany
Interact Cardiovasc Thorac Surg 16:643-8. 2013..Changes in both patient profile and type of operations have been observed in recent years. Therefore, we analysed current wound healing complications after median sternotomy at our centre...
- Surgical treatment of cardiac hydatid disease in 13 patientsEylem Tuncer
Department of Cardiovascular Surgery, Kosuyolu Heart and Research Hospital, 34846 Kartal, Istanbul, Turkey
Tex Heart Inst J 37:189-93. 2010..One patient experienced a recurrence 1 year postoperatively. We discuss our surgical approaches, the outcomes in our patients, and diagnostic and therapeutic recommendations...
- Aprotinin in cardiac surgery patients: is the risk worth the benefit?Sotiris C Stamou
Department of Thoracic and Cardiovascular Surgery, Carolinas Heart and Vascular Institute, Carolinas Medical Center, Charlotte, NC 28203, USA
Eur J Cardiothorac Surg 36:869-75. 2009..Our study sought to compare the efficacy, early and late mortality and major morbidity associated with aprotinin compared with e-aminocaproic acid (EACA) in cardiac surgery operations...
- Do antioxidant vitamins have an anti-arrhythmic effect following cardiac surgery? A meta-analysis of randomised controlled trialsLeanne Harling
Department of Surgery and Cancer, Imperial College London, 10th Floor QEQM Building, St Mary s Hospital, London W2 1NY, UK
Heart 97:1636-42. 2011..This study aims to provide a quantitative summary of the current evidence surrounding antioxidant vitamins and POAF prevention...
- Pharmacologic prophylaxis for atrial fibrillation following cardiac surgery: a systematic reviewIoanna Koniari
Cardiothoracic Surgery Department, Patras University, School of Medicine, Rion Patras, Greece
J Cardiothorac Surg 5:121. 2010....
- Relationship between exercise tolerance and muscle strength following cardiac rehabilitation: comparison of patients after cardiac surgery and patients with myocardial infarctionTakahiro Sumide
Juntendo Sports Clinic, Juntendo University Hospital, 3 1 3 Hongo, Bunkyo ku, Tokyo 113 8431, Japan
J Cardiol 54:273-81. 2009..The purpose of the present study was to assess the relationship between exercise tolerance and muscle strength following CR in patients after cardiac surgery and patients with MI...
- The concept of negative pressure wound therapy (NPWT) after poststernotomy mediastinitis--a single center experience with 54 patientsIna C Ennker
Mediclin Herzzentrum Lahr Baden, Abteilung Herzchirurgie, Hohbergweg 2, 77933 Lahr, Germany
J Cardiothorac Surg 4:5. 2009..We report about our experiences and complications using this therapy in a set of 54 patients out of 3668 patients undergoing cardiac surgery in our institution between January 2005 and April 2007...
- Delirium: an independent predictor of functional decline after cardiac surgeryJames L Rudolph
Geriatric Research, Education, and Clinical Center, Veterans Affairs Boston Healthcare System, Boston, Massachusetts 02130, USA
J Am Geriatr Soc 58:643-9. 2010..To determine whether patients who developed delirium after cardiac surgery were at risk of functional decline...
- Prolonged intensive care unit stay in cardiac surgery: risk factors and long-term-survivalOrtrud Vargas Hein
Department of Anesthesiology and Intensive Care Medicine, Campus Charite Mitte, Charite University Medicine Berlin, Berlin, Germany
Ann Thorac Surg 81:880-5. 2006....
- EuroSCORE: a systematic review of international performanceA Gogbashian
The Royal College of Surgeons of England, 35 43 Lincoln s Inn Fields, London WC2A 3PN, UK
Eur J Cardiothorac Surg 25:695-700. 2004..Overall, however, EuroSCORE is the most rigorously evaluated scoring system in cardiac surgery...
- Coagulation disorders of cardiopulmonary bypass: a reviewDomenico Paparella
Division of Cardiac Surgery, Dipartimento di Emergenza e Trapianti di Organo, University of Bari, Piazza Giulio Cesare 11, 70100 Bari, Italy
Intensive Care Med 30:1873-81. 2004..Postoperative bleeding is one of the most common complications of cardiac surgery...
- Phase II, randomized, controlled trial of high-dose N-acetylcysteine in high-risk cardiac surgery patientsMichael Haase
Department of Intensive Care, Austin Hospital, University of Melbourne, Australia
Crit Care Med 35:1324-31. 2007..To assess the effect of high-dose N-acetylcysteine on renal function in cardiac surgery patients at higher risk of postoperative renal failure...
- Health-related quality of life and post-traumatic stress disorder in patients after cardiac surgery and intensive care treatmentC Stoll
Departments of Anaesthesiology, Cardiac Surgery, and Psychiatry, Ludwig Maximilians University, Munich, Germany
J Thorac Cardiovasc Surg 120:505-12. 2000....
- Readmission to the intensive care unit after "fast-track" cardiac surgery: risk factors and outcomesAlexander Kogan
Cardiothoracic Surgery, Rabin Medical Center, Beilinson Campus, Sackler School of Medicine, Tel Aviv University, Petah Tiqva, Israel
Ann Thorac Surg 76:503-7. 2003..Readmission to the ICU, traditionally used as a quality index, has not been investigated in these patients. The aim of this study was to assess the causes, risk factors, and outcomes associated with readmission to the ICU...
- Percutaneous versus surgical closure of secundum atrial septal defect: comparison of early results and complicationsGianfranco Butera
Pediatric Cardiology, Istituto Policlinico San Donato, San Donato Milanese MI, Italy
Am Heart J 151:228-34. 2006..Surgical closure of atrial septal defect (ASD) provides excellent results. Given the increasing popularity of percutaneous techniques, a comparison between the 2 methods is needed...
- Continuous mixed venous and central venous oxygen saturation in cardiac surgery with cardiopulmonary bypassPierre Yves Lequeux
Department of Anesthesiology, Intensive Care Unit, CHU Tivoli, La Louviere, Belgium
Eur J Anaesthesiol 27:295-9. 2010..The influence of surgery, cardiopulmonary bypass and anaesthesia drugs on the relationship between SvO2 and ScvO2 has never been studied...
- Pulmonary abnormalities after cardiac surgery are better explained by atelectasis than by increased permeability oedemaJ Verheij
Department of Intensive Care, Institute for Cardiovascular Research, Vrije Universiteit Medical Centre, Amsterdam, The Netherlands
Acta Anaesthesiol Scand 49:1302-10. 2005..Cardiac surgery can be complicated by pulmonary abnormalities, but it is unclear how various manifestations interrelate...
- Ketamine attenuates delirium after cardiac surgery with cardiopulmonary bypassJudith A Hudetz
Department of Anesthesiology, Medical College of Wisconsin and Clement J Zablocki Veterans Administration Medical Center, Milwaukee, WI, USA
J Cardiothorac Vasc Anesth 23:651-7. 2009..To determine if ketamine attenuates postoperative delirium concomitant with an anti-inflammatory effect in patients undergoing cardiac surgery using cardiopulmonary bypass...
- Atrial fibrillation correction surgery: lessons from the Society of Thoracic Surgeons National Cardiac DatabaseJames S Gammie
Division of Cardiac Surgery, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
Ann Thorac Surg 85:909-14. 2008..We also examined the subset of patients having mitral valve surgery to determine whether concurrent surgical AF correction procedures were associated with an increased risk of morbidity or mortality...
- Preoperative C-reactive protein predicts mid-term outcome after cardiac surgeryGiangiuseppe Cappabianca
Division of Cardiac Surgery, Dipartimento d Emergenza e Trapianti d Organo, University of Bari, Bari, Italy
Ann Thorac Surg 82:2170-8. 2006..The study objective was to evaluate the effect of CRP on short-term and mid-term outcome after cardiac surgery...
- Is right ventricular systolic function reduced after cardiac surgery? A two- and three-dimensional echocardiographic studyGloria Tamborini
Centro Cardiologico Monzino, I R C C S, Institute of Cardiology, University of Milan, Via Parea 4, 20138 Milan, Italy
Eur J Echocardiogr 10:630-4. 2009..Aims of this study were to evaluate RV function in patients with mitral valve prolapse undergoing surgical valvular repair and to compare and correlate 3D RV ejection fraction (RVEF) with TAPSE and PSV before and after surgery...
- Guidelines for reporting data and outcomes for the surgical treatment of atrial fibrillationRichard J Shemin
Division of Cardiothoracic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, California, USA
Ann Thorac Surg 83:1225-30. 2007..Thus, more reliable evaluation and comparisons of results will advance our knowledge and further the development and application of these procedures...
- Long-term effects of surgical septal myectomy on survival in patients with obstructive hypertrophic cardiomyopathySteve R Ommen
Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
J Am Coll Cardiol 46:470-6. 2005..This study sought to determine the impact of surgical myectomy on long-term survival in hypertrophic cardiomyopathy (HCM)...
- Postoperative atrial fibrillation is not correlated to C-reactive proteinAnders J Ahlsson
Department of Cardiothoracic Surgery and Anesthesiology, Orebro University Hospital, Orebro, Sweden
Ann Thorac Surg 83:1332-7. 2007..The aim of this study was to investigate differences between patients with and without postoperative AF with special regard to C-reactive protein (CRP) serum levels...
- The incidence, risk factors, and outcome of transfusion-related acute lung injury in a cohort of cardiac surgery patients: a prospective nested case-control studyAlexander P J Vlaar
Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
Blood 117:4218-25. 2011..In conclusion, the incidence of TRALI is high in cardiac surgery patients and associated with adverse outcome. Our results suggest that cardiac surgery patients may benefit from exclusion of blood products containing HLA/HNA antibodies...
- Late complications in patients after repair of aortic coarctation: implications for managementJoris W J Vriend
Department of Cardiology, Academic Medical Centre, Amsterdam, The Netherlands
Int J Cardiol 101:399-406. 2005..In this review, these complications, with particular reference to late hypertension, are discussed and strategies for the clinical management of post-coarctectomy patients are described...
- Risk adjustment for congenital heart surgery: the RACHS-1 methodKathy J Jenkins
Department of Cardiology, Children s Hospital, Boston, MA, USA
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 7:180-4. 2004..Underlying assumptions about RACHS-1 risk categories, inclusion and exclusion criteria, and appropriate and inappropriate uses are discussed...
- Epidemiology, mechanisms, and risks: American College of Chest Physicians guidelines for the prevention and management of postoperative atrial fibrillation after cardiac surgeryCharles W Hogue
Department of Anesthesiology, Washington University School of Medicine, 660 South Euclid Ave, Box 8054, St Louis, MO 63110, USA
Chest 128:9S-16S. 2005....
- Postoperative mediastinitis in cardiac surgery - microbiology and pathogenesisB Gardlund
Department of Infectious Diseases, Karolinska Hospital, Stockholm, Sweden
Eur J Cardiothorac Surg 21:825-30. 2002..32%) of 9557 consecutive cardiac surgery procedures. The study was done to describe the variation in clinical characteristics and microbiological etiology in mediastinitis...
- Transfusion of blood components and postoperative infection in patients undergoing cardiac surgeryS R Leal-Noval
Critical Care Division, Hospital Universitario Virgen del Rocio, Seville, Spain
Chest 119:1461-8. 2001..To investigate the influence of blood derivatives on the acquisition of severe postoperative infection (SPI) in patients undergoing heart surgery...
- Cardiac surgery-associated acute kidney injury: a comparison of two consensus criteriaAlina M Robert
Internal Medicine, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
Ann Thorac Surg 90:1939-43. 2010..We sought to estimate the ability of both the RIFLE and and AKIN criteria to predict the risk of in-hospital mortality in the setting of cardiac surgery...
- A novel hydroxyethyl starch (Voluven) for effective perioperative plasma volume substitution in cardiac surgeryR C Gallandat Huet
Department of Anesthesiology, University Hospital Groningen, The Netherlands
Can J Anaesth 47:1207-15. 2000..To compare the new hydroxyethyl starch HES 130/0.4 (Voluven) and the standard HES 200/0.5 (pentastarch) regarding effectiveness for plasma volume substitution and safety of large volumes in heart surgery...
- Hemodynamic effects of vacuum-assisted closure therapy in cardiac surgery: assessment using magnetic resonance imagingRainer Petzina
Department of Medicine, Lund University Hospital, Lund, Sweden
J Thorac Cardiovasc Surg 133:1154-62. 2007....
- Open heart surgery in Nigeria; a work in progressBode Falase
Cardiothoracic Division, Lagos State University College of Medicine, Lagos State University Teaching Hospital, Ikeja, Lagos, Nigeria
J Cardiothorac Surg 8:6. 2013..The aim of this study is to review the experience with Open Heart Surgery at the Lagos State University Teaching Hospital and highlight the challenges encountered in developing this programme...
- Cognitive function after sevoflurane- vs propofol-based anaesthesia for on-pump cardiac surgery: a randomized controlled trialJ Schoen
Department of Anesthesiology, University of Luebeck, Ratzeburger Allee 160, D 23538 Luebeck, Germany
Br J Anaesth 106:840-50. 2011..This study was designed to determine cognitive and clinical outcomes after sevoflurane- compared with propofol-based anaesthesia for on-pump cardiac surgery and the impact of decreases in under different anaesthesia regimens...
- N-3 polyunsaturated fatty acids to prevent atrial fibrillation: updated systematic review and meta-analysis of randomized controlled trialsJavier Mariani
Fundación GESICA Grupo de Estudio de Investigación Clínica en Argentina, Buenos Aires, Argentina
J Am Heart Assoc 2:e005033. 2013..We aimed to assess the effects of therapy with n-3 PUFAs on the incidence of recurrent AF and on postoperative AF...
- Hybrid procedures: adverse events and procedural characteristics--results of a multi-institutional registryRalf Holzer
Department of Cardiology, Nationwide Children s Hospital, Columbus, Ohio 43205, USA
Congenit Heart Dis 5:233-42. 2010....
- Risk factors for nonocclusive mesenteric ischemia after elective cardiac surgeryHeinrich Volker Groesdonk
Department of Thoracic and Cardiovascular Surgery, Saarland University Medical Center, Homburg Saar, Germany
J Thorac Cardiovasc Surg 145:1603-10. 2013..It is crucial to early identify patients who are at risk of developing this complication. The aim of this prospective study was to evaluate perioperative risk factors in a large cohort of patients undergoing elective cardiac surgery...
- Update on acute kidney injury after cardiac surgeryAndrew Shaw
Department of Anesthesiology, Duke University Medical Center, Durham, NC 27710, USA
J Thorac Cardiovasc Surg 143:676-81. 2012..To review the current state of clinical practice and discuss recent advances in the diagnosis and management of acute kidney injury (AKI) in the context of cardiac surgery...
- Daptomycin as supportive treatment option in patients developing mediastinitis after open cardiac surgeryFlorian Weis
Department of Anaesthesiology, University of Munich LMU, Marchioninistrasse 15, 81377, Munich, Germany
J Cardiothorac Surg 7:81. 2012..Within this study, we report the successful use of daptomycin as supportive therapy in patients developing mediastinitis after open cardiac surgery...
- The association of preoperative glycemic control, intraoperative insulin sensitivity, and outcomes after cardiac surgeryHiroaki Sato
Department of Anaesthesia, Royal Victoria Hospital, McGill University Health Center, Montreal, Quebec, Canada H3A 1A1
J Clin Endocrinol Metab 95:4338-44. 2010..The impairment of insulin sensitivity, a marker of surgical stress, is important for outcomes...
- Treatment outcomes of postoperative mediastinitis in cardiac surgery; negative pressure wound therapy versus conventional treatmentHayati Deniz
Gaziantep University Medical Faculty, Department of Cardiovascular Surgery, Sehitkamil, Gaziantep, Turkey
J Cardiothorac Surg 7:67. 2012..The aim of the present study is to compare negative pressure wound therapy versus conventional treatment outcomes at postoperative mediastinitis after cardiac surgery...
- Outcome and survival analysis of intestinal ischaemia following cardiac surgeryPhilip Y K Pang
Department of Cardiothoracic Surgery, National Heart Centre, Singapore, Singapore
Interact Cardiovasc Thorac Surg 15:215-8. 2012..The purpose of this study was to analyse the outcomes and prognostic factors in patients who develop intestinal ischaemia following cardiac surgery...
- The effect of blood transfusion on pulmonary permeability in cardiac surgery patients: a prospective multicenter cohort studyAlexander P J Vlaar
Department of Intensive Care Medicine, Academic Medical Center, Amsterdam, The Netherlands
Transfusion 52:82-90. 2012..Mediators of increased pulmonary vascular leakage after transfusion are unknown. We hypothesized that factors may include antibodies or bioactive lipids, which have been implicated in transfusion-related acute lung injury...
- The pathophysiology of cardiac surgery-associated acute kidney injury (CSA-AKI)R Bellomo
Department of Intensive Care, Austin Hospital, Melbourne, Australia
Int J Artif Organs 31:166-78. 2008..The administration of N-acetylcysteine to protect the kidney from oxidative stress is not recommended. There is marked lack of randomised controlled trials in this field...
- Gastrointestinal complications in patients undergoing heart operation: an analysis of 8709 consecutive cardiac surgical patientsAbeel A Mangi
Division of General and Gastrointestinal Surgery, Department of Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Ann Surg 241:895-901; discussion 901-4. 2005..Systematic analysis of risk factors to allow early identification of patients at risk for GI complication may lead to the development of strategies to mitigate this complication as well as to optimize management after its occurrence...
- Myocardial Assistance by Grafting a New Bioartificial Upgraded Myocardium (MAGNUM trial): clinical feasibility studyJuan C Chachques
Department of Cardiovascular Surgery, Pompidou Hospital, Paris, France
Ann Thorac Surg 85:901-8. 2008..We evaluated the feasibility and safety of intrainfarct cell therapy associated with a cell-seeded collagen scaffold grafted onto infarcted ventricles...
- Postoperative white blood cell count predicts atrial fibrillation after cardiac surgeryGudrun Lamm
Department of Cardiology and Intensive Care, General Hospital Wels, Wels, Austria
J Cardiothorac Vasc Anesth 20:51-6. 2006..The purpose of the present study was to investigate the correlation between the postoperative white blood cell (WBC) count as a marker of inflammation and the development of postoperative AF after cardiac surgery...
- Acute hemodynamic effects of cardiac resynchronization therapy in patients with poor left ventricular function during cardiac surgeryMohamed A Soliman Hamad
Department of Cardiothoracic Surgery, Catharina Hospital, Eindhoven, The Netherlands
J Card Surg 24:585-90. 2009..We investigated the acute hemodynamic response using LVdP/dt(max) in patients with depressed LV function and conduction disturbances undergoing cardiac surgery...
- Corticosteroids and outcome in children undergoing congenital heart surgery: analysis of the Pediatric Health Information Systems databaseSara K Pasquali
Department of Pediatrics, Duke University Medical Center, Duke Clinical Research Institute, Durham, NC 27715, USA
Circulation 122:2123-30. 2010..Children undergoing congenital heart surgery often receive corticosteroids with the aim of reducing the inflammatory response after cardiopulmonary bypass; however, the value of this approach is unclear...
- Cross-clamp time is an independent predictor of mortality and morbidity in low- and high-risk cardiac patientsNael Al-Sarraf
Department of Cardiothoracic Surgery, St James s Hospital, Dublin 8, Ireland
Int J Surg 9:104-9. 2011..We sought to assess the effects of aortic cross-clamp time (XCL) on outcome following cardiac surgery in low- and high-risk patients...
- Changing from aprotinin to tranexamic acid results in increased use of blood products and recombinant factor VIIa for aortic surgery requiring hypothermic arrestRoman M Sniecinski
Department of Anesthesiology, Emory University School of Medicine, Atlanta, GA 30322, USA
J Cardiothorac Vasc Anesth 24:959-63. 2010..This study was undertaken to determine what, if any, the impact of changing antifibrinolytic agents (from aprotinin to tranexamic acid) for deep hypothermic circulatory arrest cases would have on blood bank resource utilization...
- Major infection after pediatric cardiac surgery: a risk estimation modelGregory M Barker
Duke University Medical Center, Durham, North Carolina, USA
Ann Thorac Surg 89:843-50. 2010..In pediatric cardiac surgery, infection is a leading cause of morbidity and mortality. We created a model to predict risk of major infection in this population...
- Mild-to-moderate COPD as a risk factor for increased 30-day mortality in cardiac surgeryM Ried
Department of Cardiothoracic Surgery, University Medical Center Regensburg, Regensburg, Germany
Thorac Cardiovasc Surg 58:387-91. 2010..Chronic obstructive pulmonary disease (COPD) is still a serious comorbidity in surgical procedures. We assessed the impact of mild to moderate COPD in a modern cardiac surgery unit...
- Left atrial radiofrequency ablation during mitral valve surgery: a prospective randomized multicentre study (SAFIR)Philippe Chevalier
Department of Cardiology Rythmology, Hospices Civils de Lyon, Hopital Cardiologique Louis Pradel, CHU Louis Pradel, avenue du doyen Lepine, Lyon Cedex 03, France
Arch Cardiovasc Dis 102:769-75. 2009..Randomized studies evaluating left atrial radiofrequency ablation (RFA) in patients with persistent atrial fibrillation undergoing mitral valve surgery are scarce and monocentric...
- Management of intraoperative fluid balance and blood conservation techniques in adult cardiac surgeryGeorge Vretzakis
Cardiac Anaesthesia Unit, University Hospital of Larissa, Greece
Heart Surg Forum 14:E28-39. 2011....
- Vacuum-assisted wound closure is superior to primary rewiring in patients with deep sternal wound infectionA Assmann
Department of Cardiovascular Surgery, University Hospital, Duesseldorf, Germany
Thorac Cardiovasc Surg 59:25-9. 2011..The study additionally focuses on defining predictors for the failure of primary rewiring and its impact on postoperative outcome...
- Prevention of atrial fibrillation in cardiac surgery: time to consider a multimodality pharmacological approachKwok M Ho
Department of Intensive Care Medicine, Royal Perth Hospital and School of Population Health, University of Western Australia, Perth, WA 6000, Australia
Cardiovasc Ther 28:59-65. 2010..Randomized controlled trials evaluating the effectiveness of a multimodality pharmacological approach in patients at high-risk of AF after cardiac surgery are needed...
- Cardiovascular magnetic resonance and PET-CT of left atrial paragangliomaAnderanik Tomasian
Department of Radiological Sciences, University of California at Los Angeles, USA
J Cardiovasc Magn Reson 12:1. 2010....
- Prevalence of left ventricular systolic dysfunction in adults with repaired tetralogy of fallotCraig S Broberg
Oregon Health and Science University, Portland, Oregon
Am J Cardiol 107:1215-20. 2011..Severity or duration of pulmonary regurgitation was not different. In conclusion, LV systolic dysfunction was found in 21% of adult patients with TOF and was associated with shunt duration, RV dysfunction, and arrhythmia...
- Improved outcomes associated with intraoperative steroid use in high-risk pediatric cardiac surgeryNadia A Clarizia
The Labatt Family Heart Centre, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada
Ann Thorac Surg 91:1222-7. 2011..Corticosteroids are commonly administered perioperatively in pediatric cardiac surgery to reduce cardiopulmonary bypass induced inflammation. However, their effects on outcomes and potential for adverse events are not well defined...
- Increased central aortic stiffness and left ventricular mass in normotensive young subjects after successful coarctation repairPhalla Ou
Department of Pediatric Radiology, Hopital Necker Enfants Malades, University Rene Descartes Paris 5, Paris, France
Am Heart J 155:187-93. 2008..Hypertension occurs in 20% to 40% of survivors of anatomically successful repair of aortic coarctation (CoA). The aim of the present study was to examine the role of central aortic function in this setting...
- Minimally invasive perventricular device closure of an isolated perimembranous ventricular septal defect with a newly designed delivery system: preliminary experienceXing Quansheng
Pediatric Cardiovascular Centre, Qingdao Children s Hospital, Qingdao, China
J Thorac Cardiovasc Surg 137:556-9. 2009..We sought to summarize the preliminary clinical experience of minimally invasive transthoracic device closure of perimembranous ventricular septal defects with a new delivery system without cardiopulmonary bypass...
- Intraoperative device closure of doubly committed subarterial ventricular septal defects: initial experienceQiang Chen
Department of Cardiovascular Surgery, Union Hospital, Fujian Medical University, Fuzhou, People s Republic of China
Ann Thorac Surg 90:869-73. 2010..The purpose of this study was to evaluate the safety and feasibility of intraoperative device closure of the doubly committed subarterial ventricular septal defect (VSD)...
- A comparison of aprotinin and lysine analogues in high-risk cardiac surgeryDean A Fergusson
Ottawa Health Research Institute, Ottawa, Canada
N Engl J Med 358:2319-31. 2008..We sought to determine whether aprotinin was superior to either tranexamic acid or aminocaproic acid in decreasing massive postoperative bleeding and other clinically important consequences...
- Impact of postoperative hyperglycemia following surgical repair of congenital cardiac defectsGermano Falcao
Department of Pediatrics, Driscoll Children s Hospital, Corpus Christi, TX 78411, USA
Pediatr Cardiol 29:628-36. 2008..Hyperglycemia is common in children following surgical repair or palliation of congenital cardiac defects. Postoperative hyperglycemia is associated with increased morbidity and mortality in these patients...
- Impact of stroke on therapeutic decision making in infective endocarditisLaurent Derex
Unité de Soins Intensifs Neurovasculaires, Department of Neurology, Hopital Neurologique, University of Lyon, 59 Boulevard Pinel, 69003, Lyon, France
J Neurol 257:315-21. 2010..Early surgery appears safe in patients presenting transient ischemic attacks or "silent" cerebral embolism...
- Association between intraoperative and early postoperative glucose levels and adverse outcomes after complex congenital heart surgeryAngelo Polito
Department of Cardiology, Children s Hospital Boston, Harvard Medical School, Boston, MA 02115, USA
Circulation 118:2235-42. 2008..This study sought to determine whether associations exist between perioperative glucose exposure, prolonged hospitalization, and morbid events after complex congenital heart surgery...
- The impact of nosocomial infections on patient outcomes following cardiac surgeryM H Kollef
Department of Internal Medicine, Pulmonary and Critical Care, Washington University School of Medicine, St Louis, MO 63110, USA
Chest 112:666-75. 1997..To evaluate the relationship between nosocomial infections and clinical outcomes following cardiac surgery, and to identify risk factors for the development of nosocomial infections in this patient population...
- Aortic arch shape deformation after coarctation surgery: effect on blood pressure responsePhalla Ou
INSERM UMR_S678, Faculté de Médecine Pitié Salpêtrière, Paris, France
J Thorac Cardiovasc Surg 132:1105-11. 2006..We sought to investigate the effect of particular deformations of aortic arch shape on blood pressure response in children who had undergone successful repair of coarctation of the aorta...
- Interleukin-10 and its role in clinical immunoparalysis following pediatric cardiac surgeryMeredith L Allen
Critical Care Group Portex Unit, Institute of Child Health, University College London, UK
Crit Care Med 34:2658-65. 2006....
- Tetralogy of fallot: yesterday and todayJoanne P Starr
Department of Surgery, University of Medicine and Dentistry of New Jersey, Newark, NJ, 07103, USA
World J Surg 34:658-68. 2010..This article presents a review of TOF, including the history of surgical treatment, present-day approaches, and long-term outcomes...
- Postoperative cognitive dysfunction after cardiac surgeryLan Gao
Laboratory of Anesthesia, Department of Anesthesia and Research Centre, Centre Hospitalier de l University de Montreal, Hospital Notre Dame, QC, Canada
Chest 128:3664-70. 2005..The purpose of this review is to discuss recent developments in our understanding of the pathophysiologic mechanisms, prevention, and treatments that have been designed to ameliorate brain dysfunction after cardiac surgery...
- A small post-operative rise in serum creatinine predicts acute kidney injury in children undergoing cardiac surgeryMichael Zappitelli
Department of Pediatrics, McGill University Health Centre, Montreal Children s Hospital, Quebec, Canada
Kidney Int 76:885-92. 2009..65). Our study shows that AKI after pediatric heart surgery is common and is a risk factor for poorer outcome. Small post-operative increases in serum creatinine may assist in the early prediction of AKI...
- [Nosocomial infections in pediatric patients following cardiac surgery]M T Guardia Camí
Servicio de Pediatria, Unidad Integrada Hospital Sant Joan de Déu Hospital Clínic i Provincial de Barcelona, Barcelona, Spain
An Pediatr (Barc) 69:34-8. 2008..This study was undertaken to determine the NI rate, main risk factors, and microbial spectrum in a paediatric intensive care unit (PICU) for this group of patients...
- Primary cardiac tumours: eighteen years of surgical experience on 21 patientsNicolo Piazza
McGill University, 3755 Cote Ste Catherine Road, Montreal, Quebec H3T 1E2, Canada
Can J Cardiol 20:1443-8. 2004..The literature on primary cardiac tumours is relatively limited because of their rare occurrence...
- Does the choice of risk-adjustment model influence the outcome of surgeon-specific mortality analysis? A retrospective analysis of 14,637 patients under 31 surgeonsS W Grant
University Hospital of South Manchester NHS Foundation Trust, Southmoor Road, Manchester M23 9LT, UK
Heart 94:1044-9. 2008..To compare implications of using the logistic EuroSCORE and a locally derived model when analysing individual surgeon mortality outcomes...
- Preoperative cerebral oxygen saturation and clinical outcomes in cardiac surgeryMatthias Heringlake
Cardiac Anesthesia Unit, Department of Anesthesiology, University of Lubeck, Lubeck, Germany
Anesthesiology 114:58-69. 2011..The current study was designed to determine the relation between preoperative cerebral oxygen saturation (Sco2), variables of cardiopulmonary function, mortality, and morbidity in a heterogeneous cohort of cardiac surgery patients...
- Clinical management of infants with hypoplastic left heart syndrome in the United States, 1988-1997Ruey Kang R Chang
Division of Cardiology, Department of Pediatrics, Harbor UCLA Medical Center, Torrance, California 90509, USA
Pediatrics 110:292-8. 2002..To evaluate changes in the clinical management of infants with hypoplastic left heart syndrome (HLHS) over a 10-year period...
- Deep sternal wound infections following open heart surgery in Iceland: a population-based studySteinn Steingrimsson
Department of Cardiothoracic Surgery, Landspitali University Hospital, Reykjavik, Iceland
Scand Cardiovasc J 42:208-13. 2008..The aim of this nationwide case-control study was to study the epidemiology and identify risk factors of deep sternal wound infections (DSWI) in Iceland...
- Errors and the burden of errors: attitudes, perceptions, and the culture of safety in pediatric cardiac surgical teamsAgnes Bognar
Department of Ophthalmology, School of Medicine, University of Szeged, Szeged, Hungary
Ann Thorac Surg 85:1374-81. 2008..We assessed the perceptions and attitudes of surgical teams relative to committing errors, the impact of errors, and the culture of safety...
- Temporary biventricular pacing postcardiopulmonary bypass in patients with reduced ejection fractionJochen D Muehlschlegel
Department of Anesthesiology, Perioperative and Pain Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Card Surg 23:324-30. 2008..This study analyzed the response of BiV versus single ventricle lead pacing on hemodynamics and left ventricular (LV) function immediately following CPB...
- Myths about surgical myectomy: rumors of its death have been greatly exaggeratedBarry J Maron
Am J Cardiol 101:887-9. 2008
- Nosocomial infections in pediatric cardiac surgery, ItalyM Valera
Department of Immuno-Infectivology, University of Turin, Italy
Infect Control Hosp Epidemiol 22:771-5. 2001..The higher NI incidence in patients with an open chest postoperatively suggests that an alternative antibiotic strategy should be considered for these patients...
- Development of a Surgical and Transcatheter Polymeric Heart ValveJACK CABELL GRIFFIS; Fiscal Year: 2012..In this application, we propose the development and testing of a novel polymeric heart valve, prepared from a resilient, highly durable material with exquisite shape memory properties. ..
- CLINICAL LEFT VENTRICULAR BYPASS STUDIESWILLIAM BERNHARD; Fiscal Year: 1980..They will include those who cannot be adequately resuscitated at the end of a cardiac surgical operation, and others who develop cardiogenic shock within 72 hours following an uncomplicated cardiac surgical procedure. ..
- Stroke Prevention Through Atrial Appendage OcclusionJON SHERMAN; Fiscal Year: 2005..Phase II will focus on adapting the canine design for use in humans. ..
- High Dose Erythropoetin Neuroprotection Trial for Neonatal Cardiac SurgeryDean Andropoulos; Fiscal Year: 2008..This study will show if babies that are given erythropoetin have fewer delays in development than babies that do not receive the drug. [unreadable] [unreadable] [unreadable]..
- Long-term White Matter Changes Resulting from Delirium after SurgeryJames Rudolph; Fiscal Year: 2008..If the hypotheses are confirmed, this will alter our fundamental understanding of delirium as a short-term disorder and future studies can use imaging to prevent, identify, and treat delirium. [unreadable] [unreadable] [unreadable]..
- Estradiol For Neurocognitive Dysfunction After CABGCharles Hogue; Fiscal Year: 2005..The results of this study will evaluate the efficacy and safety of an easily implemented therapy for improving neurologic outcome and quality of life after CABG surgery for postmenopausal women. ..
- Modified Late Infarct Reperfusion to Prevent Post MI CHFRobert Gorman; Fiscal Year: 2006..unreadable] [unreadable]..
- APOE Genotype and Sequelae of Infant Cardiac SurgeryJames Gaynor; Fiscal Year: 2007..unreadable] [unreadable]..
- STICH Trial Radionuclide Core LaboratoryRobert Bonow; Fiscal Year: 2007..abstract_text> ..
- Cardiac Parasympathetic Effect in Exercise and RecoveryJeffrey Goldberger; Fiscal Year: 2006..abstract_text> ..
- Logical Analysis of Data and Cardiac Surgery RiskEugene Blackstone; Fiscal Year: 2006..Hence, the applicability of this work goes beyond determination of risk of patients undergoing cardiac surgery. ..
- MECHANISMS OF COMPLEMENT INDUCED MYOCARDIAL ISCHEMIAGREGORY STAHL; Fiscal Year: 2007..abstract_text> ..
- Fatty Acids and Cardiovascular HealthDariush Mozaffarian; Fiscal Year: 2007..End of Abstract) [unreadable] [unreadable] [unreadable] [unreadable] [unreadable]..
- Angiogenesis and Cardiac Growth as Heart Failure TherapyY Woo; Fiscal Year: 2008..The candidate's institution, sponsor, and chairman provide a uniquely supportive, high-caliber, educationally stimulating environment highly conducive to the achievement of these goals. ..
- Enhancing Recovery After Cardiac SurgeryLynn Doering; Fiscal Year: 2008..abstract_text> ..
- Interdisciplinary Training: Neurodevelopmental Toxicology(RMI)David Bellinger; Fiscal Year: 2008..Members of the faculty currently conduct a wealth of multidisciplinary research, which will provide trainees with ready opportunities to apply their training in ongoing research projects. [unreadable] [unreadable]..
- Vessel Remodeling During Ductus Arteriosus ClosureRonald I Clyman; Fiscal Year: 2010..These studies should increase our understanding of the mechanisms that prevent the preterm DA from closing and remodeling after birth. ..
- Strain Controlled LVAD Unloading and Post MI RemodelingBARTLEY PERRY GRIFFITH; Fiscal Year: 2010..Accordingly, we will learn the impact of controlled strain after large infarction with an interventionally applied micro VAD. ..
- Bradykinin Receptor Antagonism During Cardiopulmonary BypassMias Pretorius; Fiscal Year: 2010..These studies promise to provide important information regarding the effects of drugs that interrupt the RAS and generate new strategies to reduce morbidity in patients undergoing CPB. ..
- DEVELOPMENT OF A CHRONIC ARTIFICIAL LUNGBartley Griffith; Fiscal Year: 2001..5) Develop and validate a closed-loop, flow control algorithm to ensure fail-safe pumping by the CAL spinning disc(s); incorporate algorithm into a controller unit to be part of the overall CAL system. ..
- QUALITY OF LIFE OUTCOMES >= 5 YRS POST HEART TRANSPLANTKathleen Grady; Fiscal Year: 2004..Health-Related Implications. These data will provide information regarding (1) long-term benefits versus risks of HT, (2) patients at risk for poor outcomes, (3) and targets for interventions to improve outcomes. ..
- BIOENGINEERING-BIOLOGIC STUDY OF NON-PULSATILE PERFUSIONBartley Griffith; Fiscal Year: 2002..From these experiments, we believe that we will provide significant new information regarding tissue perfusion and arterial adaptation to, and possible impairment from, diminished or non-existent flow pulse. ..
- INNATE IMMUNITY AND MYOCARDIAL INJURYGREGORY STAHL; Fiscal Year: 2003..abstract_text> ..
- Controlled Reperfusion for Whole Body Ischemic InjuryGerald Buckberg; Fiscal Year: 2005..If this novel method of management is correct, the scheme of diagnosis and management of this almost always fatal cardiac arrest complex will change markedly. ..
- VENTRICULAR FUNCTION DURING CARDIAC SURGERYHENRY SPOTNITZ; Fiscal Year: 2005....
- BIOENGINEERING-BIOLOGIC STUDY OF NON-PULSATILE PERFUSIONBartley Griffith; Fiscal Year: 2003..From these experiments, we believe that we will provide significant new information regarding tissue perfusion and arterial adaptation to, and possible impairment from, diminished or non-existent flow pulse. ..
- The Effect of cGMP on Pulmonary Endothelial ApoptosisRobert Stephens; Fiscal Year: 2008..An understanding of how this phenomenon is regulated in acute lung injury may lead to new therapies for this severe illness. [unreadable] [unreadable] [unreadable] [unreadable]..
- SEVERE DEPRESSION IN WOMEN AFTER CARDIAC SURGERYLynn Doering; Fiscal Year: 2002..The research proposed as part of the award is designed to completed the applicant's formal and laboratory training. ..
- NEUROBEHAVIORAL SEQUELAE OF CARDIAC SURGERYDavid Bellinger; Fiscal Year: 2005..abstract_text> ..
- Neuroprotection with serpins during cardiac surgeryRichard A Jonas; Fiscal Year: 2010..The final phase will study mechanisms of vascular protection afforded by aprotinin. The proposed study has the potential to reduce the risk of brain injury in children and adults undergoing heart surgery. ..
- Bacteremia from Dental Extraction vs. Oral HygienePeter Lockhart; Fiscal Year: 2004..Additionally, we will have unique and critical data for the development of both future research and evidence-based guidelines concerning antibiotic prophylaxis for individuals currently felt to be at risk for DSI. ..
- Retrograde In Situ Isolated Cardiac Gene DeliveryCharles Bridges; Fiscal Year: 2004..Further development of this approach may ultimately lead to the development of clinically relevant techniques of therapeutic cardiac gene delivery for the treatment of heart failure of diverse etiologies. ..
- Quality Improvement and Outcomes for Strokes After CABGDONALD LIKOSKY; Fiscal Year: 2004..abstract_text> ..
- Mitral Annular Remodeling for MR TherapyKiyotaka Fukamachi; Fiscal Year: 2005..Therefore, this proposed research program is an important first step in this novel procedure's development as one potential therapeutic option for high-risk CHF patients with functional MR. ..
- Role of IGF-1 In Diastolic Dysfunction of AgingLeanne Groban; Fiscal Year: 2003..This study will provide the groundwork for future studies examining how IGF-1 signaling may modulate the programming and gene expression of the senescent myocardium. ..
- Robotically Assisted Mouse InterventionsKevin Cleary; Fiscal Year: 2008..3. Perform a feasibility study using 10 mice to demonstrate the ability of the robot to biopsy the mouse flank as selected on the MRI images and evaluate the accuracy of the system. [unreadable] [unreadable] [unreadable]..
- OR2020 Workshop: Operating Room of the FutureKevin Cleary; Fiscal Year: 2004..The workshop is currently scheduled to be held from April 16-17, 2004, at Turf Valley Conference Center in Ellicot City, Maryland. ..
- Software Toolkit for Image Guided SurgeryKevin Cleary; Fiscal Year: 2005..Dissemination activities will be undertaken with the aim of fostering the use of the toolkit in research and clinical applications. ..
- Continued Development for The Image-guided Surgical Toolkit Project (IGSTK)Kevin Cleary; Fiscal Year: 2009....
- CT fluoroscopy guided robotically assisted lung biopsyKevin Cleary; Fiscal Year: 2005..The system will be validated in phantom and animal studies. The R33 phase will result in a system that is ready for clinical trials. ..