injury severity score

Summary

Summary: An anatomic severity scale based on the Abbreviated Injury Scale (AIS) and developed specifically to score multiple traumatic injuries. It has been used as a predictor of mortality.

Top Publications

  1. ncbi Scoring of anatomic injury after trauma: AIS 98 versus AIS 90--do the changes affect overall severity assessment?
    Nils O Skaga
    Department of Anaesthesiology, Ulleval University Hospital, 0407 Oslo, Norway
    Injury 38:84-90. 2007
  2. ncbi The coagulopathy of trauma: a review of mechanisms
    John R Hess
    Department of Pathology, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    J Trauma 65:748-54. 2008
  3. ncbi A modification of the injury severity score that both improves accuracy and simplifies scoring
    T Osler
    Department of Surgery, University of Vermont, Burlington 05405, USA
    J Trauma 43:922-5; discussion 925-6. 1997
  4. pmc Consensus statement on injury definitions and data collection procedures in studies of football (soccer) injuries
    C W Fuller
    Centre for Sports Medicine, University of Nottingham, Nottingham, UK
    Br J Sports Med 40:193-201. 2006
  5. pmc Thrombelastography and biomarker profiles in acute coagulopathy of trauma: a prospective study
    Sisse R Ostrowski
    Section for Transfusion Medicine, Capital Region Blood Bank, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Scand J Trauma Resusc Emerg Med 19:64. 2011
  6. ncbi Primary fibrinolysis is integral in the pathogenesis of the acute coagulopathy of trauma
    Jeffry L Kashuk
    Division of Trauma, Acute Care, and Critical Care Surgery, Department of Surgery, Penn State Hershey Medical Center, College of Medicine, Hershey, PA 17033, USA
    Ann Surg 252:434-42; discussion 443-4. 2010
  7. ncbi Acute traumatic coagulopathy
    Karim Brohi
    Trauma and Critical Care Unit, Royal London Hospital, United Kingdom
    J Trauma 54:1127-30. 2003
  8. ncbi The New Injury Severity Score: a more accurate predictor of in-hospital mortality than the Injury Severity Score
    Andre Lavoie
    Centre Hospitalier Affilie Universitaire De Quebec, Enfant Jésus Hospital, Quebec City, Quebec, Canada
    J Trauma 56:1312-20. 2004
  9. ncbi AIS 2005: a contemporary injury scale
    Thomas A Gennarelli
    Department of Neurosurgery, Medical College of Wisconsin, 9200 W, Wisconsin Avenue, Milwaukee, WI 53226, United States
    Injury 37:1083-91. 2006
  10. ncbi Prevalence of pelvic fractures, associated injuries, and mortality: the United Kingdom perspective
    Peter V Giannoudis
    Department of Orthopaedics and Trauma, Leeds General Infirmary, Leeds, United Kingdom
    J Trauma 63:875-83. 2007

Detail Information

Publications320 found, 100 shown here

  1. ncbi Scoring of anatomic injury after trauma: AIS 98 versus AIS 90--do the changes affect overall severity assessment?
    Nils O Skaga
    Department of Anaesthesiology, Ulleval University Hospital, 0407 Oslo, Norway
    Injury 38:84-90. 2007
    ..Our aim was to evaluate whether the use of different coding dictionaries affected estimation of Injury Severity Score (ISS), New Injury Severity Score (NISS) and probability of survival (Ps) according to TRISS in a hospital-..
  2. ncbi The coagulopathy of trauma: a review of mechanisms
    John R Hess
    Department of Pathology, University of Maryland Medical Center, Baltimore, Maryland 21201, USA
    J Trauma 65:748-54. 2008
    ..Coagulopathy associated with severe injury complicates the control of bleeding and is associated with increased morbidity and mortality in trauma patients. The causes and mechanisms are multiple and yet to be clearly defined...
  3. ncbi A modification of the injury severity score that both improves accuracy and simplifies scoring
    T Osler
    Department of Surgery, University of Vermont, Burlington 05405, USA
    J Trauma 43:922-5; discussion 925-6. 1997
    The Injury Severity Score (ISS) has served as the standard summary measure of anatomic injury for more than 20 years. Nevertheless, the ISS has an idiosyncrasy that both impairs its predictive power and complicates its calculation...
  4. pmc Consensus statement on injury definitions and data collection procedures in studies of football (soccer) injuries
    C W Fuller
    Centre for Sports Medicine, University of Nottingham, Nottingham, UK
    Br J Sports Med 40:193-201. 2006
    ..Recommendations are made on how the incidence of match and training injuries should be reported and a checklist of issues and information that should be included in published reports of studies of football injuries is presented...
  5. pmc Thrombelastography and biomarker profiles in acute coagulopathy of trauma: a prospective study
    Sisse R Ostrowski
    Section for Transfusion Medicine, Capital Region Blood Bank, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Scand J Trauma Resusc Emerg Med 19:64. 2011
    ..Severe injury induces an acute coagulopathy associated with increased mortality. This study compared the Thrombelastography (TEG) and biomarker profiles upon admission in trauma patients...
  6. ncbi Primary fibrinolysis is integral in the pathogenesis of the acute coagulopathy of trauma
    Jeffry L Kashuk
    Division of Trauma, Acute Care, and Critical Care Surgery, Department of Surgery, Penn State Hershey Medical Center, College of Medicine, Hershey, PA 17033, USA
    Ann Surg 252:434-42; discussion 443-4. 2010
    ..We hypothesized that postinjury PF occurs early in severe shock, leading to postinjury coagulopathy, and ultimately hemorrhage-related death...
  7. ncbi Acute traumatic coagulopathy
    Karim Brohi
    Trauma and Critical Care Unit, Royal London Hospital, United Kingdom
    J Trauma 54:1127-30. 2003
    ..Traumatic coagulopathy is thought to be caused primarily by fluid administration and hypothermia...
  8. ncbi The New Injury Severity Score: a more accurate predictor of in-hospital mortality than the Injury Severity Score
    Andre Lavoie
    Centre Hospitalier Affilie Universitaire De Quebec, Enfant Jésus Hospital, Quebec City, Quebec, Canada
    J Trauma 56:1312-20. 2004
    The purpose of this study was to determine whether the New Injury Severity Score (NISS) is a better predictor of mortality than the Injury Severity Score (ISS) in general and in subgroups according to age, penetrating trauma, and body ..
  9. ncbi AIS 2005: a contemporary injury scale
    Thomas A Gennarelli
    Department of Neurosurgery, Medical College of Wisconsin, 9200 W, Wisconsin Avenue, Milwaukee, WI 53226, United States
    Injury 37:1083-91. 2006
    ..In addition to a universal injury language, it provides measures of injury severity that can be used to stratify and classify injury severity in all body regions. Its revision, AIS 2005 will be discussed here...
  10. ncbi Prevalence of pelvic fractures, associated injuries, and mortality: the United Kingdom perspective
    Peter V Giannoudis
    Department of Orthopaedics and Trauma, Leeds General Infirmary, Leeds, United Kingdom
    J Trauma 63:875-83. 2007
    ....
  11. pmc Prevalence and predictors of sub-acute phase disability after injury among hospitalised and non-hospitalised groups: a longitudinal cohort study
    Sarah Derrett
    Injury Prevention Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, Dunedin, New Zealand
    PLoS ONE 7:e44909. 2012
    ..To date, few studies have investigated outcomes for both those who were hospitalised and those who were not...
  12. ncbi Helicopters and the civilian trauma system: national utilization patterns demonstrate improved outcomes after traumatic injury
    Joshua B Brown
    Department of Surgery, University of Rochester School of Medicine, Rochester, New York 14642 8410, USA
    J Trauma 69:1030-4; discussion 1034-6. 2010
    ..The objective of this study was to compare patient outcomes after transport from the scene of injury by HT and ground transport using a national patient sample...
  13. ncbi Prehospital airway and ventilation management: a trauma score and injury severity score-based analysis
    Daniel P Davis
    Department of Emergency Medicine, UC San Diego, San Diego, California, USA
    J Trauma 69:294-301. 2010
    ..However, recent evidence suggests that the procedure may be associated with increased mortality, possibly reflecting inadequate training, suboptimal patient selection, or inappropriate ventilation...
  14. ncbi The effect of an organized trauma system on mortality in major trauma involving serious head injury: a comparison of the United kingdom and victoria, australia
    Belinda J Gabbe
    Department of Epidemiology and Preventive Medicine, Monash University, The Alfred Hospital, Melbourne, Victoria, Australia
    Ann Surg 253:138-43. 2011
    ..To compare outcomes following major trauma involving serious head injury managed in an inclusive trauma system (Victoria, Australia) and a setting where rationalization of trauma services is absent (England/Wales)...
  15. ncbi Correlation between IL-6 levels and the systemic inflammatory response score: can an IL-6 cutoff predict a SIRS state?
    Peter V Giannoudis
    Academic Department of Trauma Surgery, Leeds University, Leeds, United Kingdom
    J Trauma 65:646-52. 2008
    ..The aim of this study was to investigate, in a group of adult trauma patients, the relationship between the interleukin-6 (IL-6) concentration, the systemic inflammatory response score (SIRS) and outcome...
  16. ncbi The impact of the AIS 2005 revision on injury severity scores and clinical outcome measures
    Kristin Salottolo
    Trauma Research Department, Swedish Medical Center, Englewood, CO 80113, USA
    Injury 40:999-1003. 2009
    ..The abbreviated injury scale (AIS) was updated in 2005 from the AIS 1998 version. The purpose of this study is to describe the effects of this change on injury severity scoring and outcome measures...
  17. ncbi Coagulopathy in severe traumatic brain injury: a prospective study
    Peep Talving
    Department of Surgery, Division of Trauma and Critical Care at the Los Angeles County, University of Southern California Medical Center, Los Angeles, California 90033, USA
    J Trauma 66:55-61; discussion 61-2. 2009
    ..The incidence and risk factors for traumatic brain injury (TBI)-associated coagulopathy after severe TBI (sTBI) and the effect of this complication on outcomes have not been evaluated in any large prospective studies...
  18. ncbi Cost, demographics and injury profile of adult pedestrian trauma in inner Sydney
    Timothy J Small
    Trauma Service, St Vincent s Hospital, University of New South Wales, Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    ANZ J Surg 76:43-7. 2006
    ..The objective of this study was to examine the demographics, injury profile, outcomes and cost of pedestrian versus motor vehicle accidents in a central city hospital in Sydney...
  19. ncbi Assessment of the clinical course with inflammatory parameters
    Hans Christoph Pape
    Department of Orthopaedic Surgery, University of Pittsburgh Medical Center, 3471 Fifth Avenue 1, 5213 Pittsburgh, PA, USA
    Injury 38:1358-64. 2007
    ..They precede the development of organ dysfunction and may be used for monitoring purposes. Among these, pro-inflammatory cytokines appear to be the most reliable parameters...
  20. pmc Causes of death in U.S. Special Operations Forces in the global war on terrorism: 2001-2004
    John B Holcomb
    U S Army Institute of Surgical Research, 3400 Rawley E Chambers Avenue, Fort Sam Houston, TX 78234, USA
    Ann Surg 245:986-91. 2007
    ..Effective combat trauma management strategies depend upon an understanding of the epidemiology of death on the battlefield...
  21. ncbi Cumulative incidence of achilles tendon rupture and tendinopathy in male former elite athletes
    Urho M Kujala
    Department of Health Sciences, University of Jyvaskyla, Jyvaskyla, Finland
    Clin J Sport Med 15:133-5. 2005
    ..To study the cumulative incidence of Achilles tendon rupture and tendinopathy among former top-level athletes...
  22. ncbi Determinants of long-term functional consequences after major trauma
    Herman R Holtslag
    Department of Rehabilitation, University Medical Center, The Netherlands
    J Trauma 62:919-27. 2007
    ..The purpose of this study was to describe the long-term functional consequences from major trauma and to quantify the effect of sociodemographic, injury-related, and physical determinants of its outcome...
  23. ncbi Acute coagulopathy of trauma: hypoperfusion induces systemic anticoagulation and hyperfibrinolysis
    Karim Brohi
    Department of Surgery, The Royal London Hospital, London, United Kingdom
    J Trauma 64:1211-7; discussion 1217. 2008
    ..The coagulopathy has recently been associated with systemic activation of the protein C pathway. This study was designed to characterize the thrombotic, coagulant and fibrinolytic derangements of trauma-induced shock...
  24. ncbi Multiple organ failure still a major cause of morbidity but not mortality in blunt multiple trauma
    D Nast-Kolb
    Department of Trauma Surgery, , Essen, Germany
    J Trauma 51:835-41; discussion 841-2. 2001
    ..METHODS: Blunt multiple trauma patients with an Injury Severity Score (ISS) > 15 points were included in this evaluation...
  25. ncbi Validation of length of hospital stay as a surrogate measure for injury severity and resource use among injury survivors
    Craig D Newgard
    Center for Policy and Research in Emergency Medicine, Department of Emergency Medicine, Oregon Health and Science University, Portland, OR, USA
    Acad Emerg Med 17:142-50. 2010
    ..This project sought to validate LOS as a proxy measure of injury severity and resource use in heterogeneous injury populations...
  26. ncbi Mortality in severely injured elderly trauma patients--when does age become a risk factor?
    Christian A Kuhne
    Department of Trauma Surgery, University Hospital Essen, Essen, Germany
    World J Surg 29:1476-82. 2005
    ..clinical study of a statewide trauma data set from 1993 through 2000 included 5375 patients with an Injury Severity Score (ISS) > or = 16 who were stratified by age...
  27. ncbi Seasonal variations in injury rates in children: evidence from a 10-year study in the Veneto Region, Italy
    Francesca Foltran
    a Unit of Biostatistics, Epidemiology and Public Health, Department of Cardiac, Thoracic and Vascular Sciences, University of Padova, Italy
    Int J Inj Contr Saf Promot 20:254-8. 2013
    ..8 for minor injuries to 2.0 for severe injuries (p <0.001). The observed pattern of increased admission in the summer months should guide resource planning and implementation of preventive strategies. ..
  28. ncbi Helicopter scene transport of trauma patients with nonlife-threatening injuries: a meta-analysis
    Bryan E Bledsoe
    The George Washington University Medical Center, Washington, DC, and Saint Johns Hospital, Minneapolis, MN, USA
    J Trauma 60:1257-65; discussion 1265-6. 2006
    ..The purpose of this study was to determine the percentage of patients transported by helicopter who have nonlife-threatening injuries...
  29. ncbi Predicting functional recovery and return to work after mutilating hand injuries: usefulness of Campbell's Hand Injury Severity Score
    Hironori Matsuzaki
    Department of Orthopaedic Surgery, Tsubame Rosai Hospital, Niigata, Japan
    J Hand Surg Am 34:880-5. 2009
    ..We investigated the effect of severity and form of mutilating hand injuries on functional recovery and return to work, and the usefulness of an injury-severity score in predicting these outcomes...
  30. ncbi Modification of the Trauma and Injury Severity Score (TRISS) method provides better survival prediction in Asian blunt trauma victims
    Akio Kimura
    Department of Emergency Medicine and Critical Care, National Center for Global Health and Medicine Hospital, Tokyo, Japan
    World J Surg 36:813-8. 2012
    ..study was to identify logistic regression models with better survival prediction than the Trauma and Injury Severity Score (TRISS) method in assessing blunt trauma (BT) victims in Japan and Thailand...
  31. pmc What are predictors of mortality in patients with pelvic fractures?
    Joerg H Holstein
    Department of Trauma, Hand, and Reconstructive Surgery, University of Saarland, Homburg, Germany
    Clin Orthop Relat Res 470:2090-7. 2012
    ..Our knowledge of factors influencing mortality of patients with pelvic ring injuries and the impact of associated injuries is currently based on limited information...
  32. ncbi Proportion of seriously injured patients admitted to hospitals in the US with a high annual injured patient volume: a metric of regionalized trauma care
    Brian S Diggs
    Department of Surgery, Center for Policy and Research in Emergency Medicine, Oregon Health and Science University, Portland, OR 97239, USA
    J Am Coll Surg 206:212-9. 2008
    ..Reliable measures are needed to evaluate the implementation of regionalized care nationally. The goal of this study was to measure the proportion of seriously injured patients treated at high injury-volume hospitals...
  33. ncbi Long-term multidimensional functional consequences of severe multiple injuries two years after trauma: a prospective longitudinal cohort study
    Helene Lundgaard Soberg
    Faculty of Medicine, University of Oslo, Department of Physical Medicine and Rehabilitation, Ulleval University Hospital, Norway
    J Trauma 62:461-70. 2007
    ..The purpose of this study was to assess functioning and quality of life after severe injuries using a prospective cohort design...
  34. ncbi Association of preexisting medical conditions with in-hospital mortality in multiple-trauma patients
    Sebastian Wutzler
    Institute for Research in Operative Medicine, University of Witten Herdecke, Cologne, Germany
    J Am Coll Surg 209:75-81. 2009
    ..The independent predictive value of specific PMCs for in-hospital mortality after adjustment for injury severity, injury pattern, age, and presence of other PMCs has not been fully elucidated...
  35. ncbi Assessment of a new trauma workflow concept implementing a sliding CT scanner in the trauma room: the effect on workup times
    P H Ping Fung Kon Jin
    Trauma Unit Department of Surgery, Academic Medical Center, VU University Medical Center, Amsterdam, The Netherlands
    J Trauma 64:1320-6. 2008
    ..This enables us to perform a complete diagnostic trauma workup, without leaving the shockroom. In this study, we assess the effect of the new Trauma Workflow Concept on the initial diagnostic workup times in the trauma room...
  36. pmc Collecting core data in severely injured patients using a consensus trauma template: an international multicentre study
    Kjetil Gorseth Ringdal
    Department of Research, Norwegian Air Ambulance Foundation, Holterveien 24, N 1440 Drøbak, Norway
    Crit Care 15:R237. 2011
    ..This study evaluated the feasibility of collecting the data variables of the international consensus-derived Utstein Trauma Template...
  37. pmc Disseminated intravascular coagulation or acute coagulopathy of trauma shock early after trauma? An observational study
    Pär I Johansson
    Section for Transfusion Medicine, Capital Region Blood Bank, Copenhagen University Hospital, Rigshospitalet, Blegdamsvej 9, DK 2100 Copenhagen, Denmark
    Crit Care 15:R272. 2011
    ..This study investigated the prevalence of overt DIC and ACoTS in trauma patients and characterized these conditions based on their biomarker profiles...
  38. ncbi Impact of helicopter transport and hospital level on mortality of polytrauma patients
    Achim Biewener
    Department of Trauma and Recontructive Surgery, University Hospital Dresden, Germany
    J Trauma 56:94-8. 2004
    ..Despite numerous studies analyzing this topic, specific advantages of helicopter transport of blunt polytrauma patients as compared with ground ambulances have not yet been identified unequivocally...
  39. pmc Medical pre-hospital management reduces mortality in severe blunt trauma: a prospective epidemiological study
    Jean Michel Yeguiayan
    Universite de Bourgogne, Service d Anesthésie et Réanimation SAMU 21, Hopital General, 3 rue Faubourg Raines, Centre Hospitalier Universitaire de Dijon, Faculte de Medecine, 21033 Dijon Cedex, France
    Crit Care 15:R34. 2011
    ..This study aimed to compare the impact of medical pre-hospital management performed by SMUR (Service Mobile d'Urgences et de Réanimation) with non-medical pre-hospital management provided by fire brigades (non-SMUR) on 30-day mortality...
  40. pmc Assessment of the effects and limitations of the 1998 to 2008 Abbreviated Injury Scale map using a large population-based dataset
    Cameron S Palmer
    Trauma Service, The Royal Children s Hospital Melbourne, Flemington Rd, Parkville 3052, Australia
    Scand J Trauma Resusc Emerg Med 19:1. 2011
    ..The Abbreviated Injury Scale (AIS) and derived scores such as the Injury Severity Score (ISS) are commonly used to quantify injury severities in trauma registries...
  41. ncbi The role of rotation thromboelastometry in early prediction of massive transfusion
    Harald Leemann
    Division of Surgery, Hospital Zug, Zug, Switzerland
    J Trauma 69:1403-8; discussion 1408-9. 2010
    ..Variables available early after injury including physiologic, laboratory, and rotation thromboelastometric (ROTEM) parameters were evaluated as predictors for the need of MT...
  42. ncbi Resuscitation before stabilization of femoral fractures limits acute respiratory distress syndrome in patients with multiple traumatic injuries despite low use of damage control orthopedics
    Robert V O'Toole
    Department of Orthopaedics, R Adams Cowley Shock Trauma Center, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
    J Trauma 67:1013-21. 2009
    ..Damage control orthopedics (DCO) with primary external fixation usually is reserved for those rare patients who do not respond to resuscitation. Our hypothesis was that this approach yields a low rate of ARDS...
  43. ncbi The clinical outcome of occult pulmonary contusion on multidetector-row computed tomography in blunt trauma patients
    Jaap Deunk
    Department of Surgery, Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands
    J Trauma 68:387-94. 2010
    ..MDCT often detects pulmonary contusion that is not visualized by CR, defined as occult pulmonary contusion (OPC). The aim of this study was to investigate whether OPC on MDCT has implications for the outcome in blunt trauma patients...
  44. ncbi The early IL-6 and IL-10 response in trauma is correlated with injury severity and mortality
    J Stensballe
    Department of Anaesthesia, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen University Hospital, 9 Blegdamsvej, Copenhagen, Denmark
    Acta Anaesthesiol Scand 53:515-21. 2009
    ..We wished to describe serum levels of IL-6 and IL-10 in the first 24 h after trauma and to assess the relationship with severity of injury and mortality...
  45. ncbi The impact of development of acute lung injury on hospital mortality in critically ill trauma patients
    Chirag V Shah
    Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA
    Crit Care Med 36:2309-15. 2008
    ..We assessed the contribution of acute lung injury to in-hospital mortality in critically ill trauma patients...
  46. ncbi Prehospital hypotension redefined
    Brandon Bruns
    Department of Surgery, Division of Burns, Trauma, and Critical Care, University of Texas Southwestern Medical School, Parkland Memorial Hospital, Dallas, Texas, USA
    J Trauma 65:1217-21. 2008
    ..However, Advanced Trauma Life Support recognizes this threshold as a late sign of shock. We undertook the current study to determine whether a higher PSBP threshold may identify patients at significant risk of death...
  47. ncbi A note on the disjointed nature of the injury severity score
    Patrick D Kilgo
    Department of Public Health Sciences, Wake Forest University School of Medicine, Winston Salem, North Carolina, USA
    J Trauma 57:479-85; discussion 486-7. 2004
    The Injury Severity Score (ISS) is widely used for anatomic severity assessments. The ISS is the sum of the squares of a patient's three worst Abbreviated Injury Scale (AIS) severities (1-6) from three specified body regions...
  48. ncbi Do trauma patients with a Glasgow Coma Scale score of 3 and bilateral fixed and dilated pupils have any chance of survival?
    Homer C Tien
    Trauma Program and the Department of Surgery, Sunnybrook and Women s College Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada
    J Trauma 60:274-8. 2006
    ..We then determined if trauma system or patient factors were responsible for the difference in mortality...
  49. ncbi Usefulness of the abbreviated injury score and the injury severity score in comparison to the Glasgow Coma Scale in predicting outcome after traumatic brain injury
    Brandon P Foreman
    University of Texas Southwestern Medical Center at Dallas, USA
    J Trauma 62:946-50. 2007
    ..We aimed to analyze the usefulness of the head abbreviated injury score (AIS), the injury severity score (ISS), and the Glasgow Coma Scale (GCS) as measures of injury severity and predictors of outcome after ..
  50. ncbi Acute coagulopathy in isolated blunt traumatic brain injury
    Arasch Wafaisade
    Department of Trauma and Orthopedic Surgery, University of Witten Herdecke, Cologne Merheim Medical Center, Ostmerheimerstr 200, 51109 Cologne, Germany
    Neurocrit Care 12:211-9. 2010
    ..This study was conducted to assess the frequency, outcome, and risk factors associated with this complication...
  51. ncbi Early use of vasopressors after injury: caution before constriction
    Jason L Sperry
    Division of Burn, Trauma, Critical Care, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    J Trauma 64:9-14. 2008
    ..We sought to characterize early vasopressor (EV) use and aggressive early crystalloid resuscitation (ECR) and their association with mortality in severely injured patients...
  52. ncbi Preperitonal pelvic packing for hemodynamically unstable pelvic fractures: a paradigm shift
    C Clay Cothren
    Department of Surgery, Denver Health Medical Center, Dencer, CO 80204, USA
    J Trauma 62:834-9; discussion 839-42. 2007
    ..We hypothesized that a modified technique of direct preperitoneal pelvic packing (PPP) would reduce the need for angiography, decrease blood transfusion requirements, and lower mortality...
  53. ncbi Assessing quality of care in a trauma referral center: benchmarking performance by TRISS-based statistics or by analysis of stratified ISS data?
    Nils O Skaga
    Department of Anesthesiology, Ulleval University Hospital, Oslo, Norway
    J Trauma 60:538-47. 2006
    ..Using prospectively collected data from Ulleval University Hospital in Norway, standard TRISS-based methods with case mix correction were compared with analysis based on ISS stratified data...
  54. ncbi A three decade analysis of factors affecting burn mortality in the elderly
    G T Lionelli
    Kansas University Medical Center, Burnett Burn Center, Kansas City, KS, USA
    Burns 31:958-63. 2005
    ..This data suggests major strides have been made in burn care, however similar success has not been achieved with inhalation injuries...
  55. ncbi Development and validation of an age-risk score for mortality predication after thermal injury
    Aimee R Moreau
    U S Army Institute of Surgical Research, Fort Sam Houston, Texas 78234 6315, USA
    J Trauma 58:967-72. 2005
    ..We hypothesized that a single "age-risk score" (AGESCORE), incorporating a cubic functional form, can be used in predictive models for mortality after burns...
  56. ncbi Time to laparotomy for intra-abdominal bleeding from trauma does affect survival for delays up to 90 minutes
    John R Clarke
    Department of Surgery, MCP Hahnemann, Philadelphia, Pennsylvania 19129, USA
    J Trauma 52:420-5. 2002
    ..We examined the relationship between survival and time in the emergency department (ED) before laparotomy for hypotensive patients bleeding from abdominal injuries...
  57. ncbi Prevalence and determinants of disabilities and return to work after major trauma
    Wouter J Vles
    Department of Surgery, St Elisabeth Hospital, Tilburg, The Netherlands
    J Trauma 58:126-35. 2005
    ..The purpose of this study was to assess the prevalence and determinants of disabilities and return to work after severe injury in a Dutch, Level I trauma center...
  58. ncbi Respiratory rate as a prehospital triage tool in rural trauma
    Hans Husum
    Department of Anesthesiology, Institute of Clinical Medicine, University Hospital of Northern Norway, Tromsoe
    J Trauma 55:466-70. 2003
    ..The present pilot study explored the accuracy of simple prehospital triage tools in the hands of nongraduate trauma care providers in the minefields of North Iraq and Cambodia...
  59. ncbi Football injuries at Asian tournaments
    Young Sul Yoon
    Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Korea
    Am J Sports Med 32:36S-42S. 2004
    ..To examine the incidences and patterns of injuries that required medical attention among Asian football players...
  60. ncbi Early coagulopathy in multiple injury: an analysis from the German Trauma Registry on 8724 patients
    Marc Maegele
    Department of Trauma and Orthopedic Surgery, University of Witten Herdecke, Cologne Merheim Medical Center, Ostmerheimerstr 200, D 51109 Cologne, Germany
    Injury 38:298-304. 2007
    ..There is increasing evidence for acute traumatic coagulopathy occurring prior to emergency room (ER) admission but detailed information is lacking...
  61. ncbi Characteristics and outcome of injured patients treated in urban trauma centers in Iran
    M Moini
    Department of Surgery, Sina Hospital, Tehran University of Medical Sciences, Iran
    J Trauma 48:503-7. 2000
    ..The Trauma and Injury Severity Score (TRISS) has been known as conventional method for this purpose...
  62. pmc UEFA Champions League study: a prospective study of injuries in professional football during the 2001-2002 season
    M Walden
    Department of Health and Society, Linkoping University, S 581 83 Linkoping, Sweden
    Br J Sports Med 39:542-6. 2005
    ..No previous study on adult football involving several different countries has investigated the incidence and pattern of injuries at the highest club competitive level...
  63. ncbi Effect of pre-existing medical conditions on in-hospital mortality: analysis of 20,257 trauma patients in Japan
    Tomohisa Shoko
    Shock Trauma and Emergency Medical Center, Tokyo Medical and Dental University Hospital of Medicine, Tokyo, Japan
    J Am Coll Surg 211:338-46. 2010
    ..The mortality rate from injury is increasing among older people. There have been no detailed reports on the relationship between pre-existing medical conditions (PMCs) and mortality from trauma among elderly people in Japan...
  64. ncbi Early inflammatory mediator response following isolated traumatic brain injury and other major trauma in humans
    M Arand
    Department of Trauma Surgery, Hand and Reconstructive Surgery, University of Ulm, Steinhovelstrasse 9, 89075 Ulm, Germany
    Langenbecks Arch Surg 386:241-8. 2001
    ..An early distinct decrease of MDA showed in patients who did not survive TBI, in contrast to survivor patients who exposed almost constant levels during the first 24 h...
  65. ncbi Whole-body multislice computed tomography as the first line diagnostic tool in patients with multiple injuries: the focus on time
    Thomas Erik Wurmb
    Department of Anesthesiology, University Hospital Wuerzburg, Wuerzburg, Germany
    J Trauma 66:658-65. 2009
    ....
  66. ncbi Hospital-based trauma registries in Uganda
    O C Kobusingye
    Makerere University, Kampala, Uganda
    J Trauma 48:498-502. 2000
    ..The registries are based on a minimal data set and a new injury severity instrument, the Kampala Trauma Score (KTS). The usefulness of the registry and the qualities of the KTS are presented...
  67. ncbi Triage and mortality in 2875 consecutive trauma patients
    R Meisler
    Department of Anaesthesia, HOC 4231, Copenhagen University Hospital, Rigshospitalet, Copenhagen, Denmark
    Acta Anaesthesiol Scand 54:218-23. 2010
    ..Most studies on trauma and trauma systems have been conducted in the United States. We aimed to describe the factors predicting mortality in European trauma patients, with focus on triage...
  68. ncbi Whole-body multislice computed tomography (MSCT) improves trauma care in patients requiring surgery after multiple trauma
    T E Wurmb
    Department of Anaesthesiology, University Hospital of Wuerzburg, Oberdürrbacherstrasse 6, 97080 Wurzburg, Germany
    Emerg Med J 28:300-4. 2011
    ..The second goal of the study was to investigate whether the diagnostic approach chosen has an impact on outcome...
  69. ncbi Major trauma CT scanning: the experience of a regional trauma centre in the UK
    Christopher M Smith
    Clinical Sciences Research Institute University of Warwick, University Hospitals Coventry and Warwickshire, Coventry, UK
    Emerg Med J 28:378-82. 2011
    ..Trauma remains a major cause of mortality and morbidity, particularly among young adults. A major trauma (whole-body) CT protocol based upon mechanism of injury was investigated in a busy emergency department...
  70. pmc Air versus ground transport of major trauma patients to a tertiary trauma centre: a province-wide comparison using TRISS analysis
    Alex D Mitchell
    Division of General Surgery, Queen Elizabeth II Health Sciences Centre, Dalhousie University, Halifax, NS
    Can J Surg 50:129-33. 2007
    ..purpose of this study was to compare the outcomes of adult (aged > 15 yr) blunt trauma patients with an Injury Severity Score (ISS) = 12 who were transported to a single tertiary trauma centre (TTC) by helicopter emergency medical ..
  71. ncbi Blunt cerebrovascular injury in patients with blunt multiple trauma: diagnostic accuracy of duplex Doppler US and early CT angiography
    Sven Mutze
    Institute of Radiology, Unfallkrankenhaus Berlin Trauma Center, Warener Str 7, 12683 Berlin, Germany
    Radiology 237:884-92. 2005
    ....
  72. ncbi Predictors of general health after major trauma
    Ian A Harris
    Orthopaedic Department, Liverpool Hospital, Liverpool, NSW, Australia
    J Trauma 64:969-74. 2008
    ..This study aims to explore possible predictors of general health after major physical trauma...
  73. ncbi Mortality of blunt polytrauma: a comparison between emergency physicians and emergency medical technicians--prospective cohort study at a level I hospital in eastern Switzerland
    Joseph J Osterwalder
    Emergency Department, Cantonal Hospital, St Gallen, Switzerland
    J Trauma 55:355-61. 2003
    ..Our objective was to establish whether the prehospital deployment of emergency physicians (EPs) rather than emergency medical technicians (EMTs) decreased mortality in blunt polytrauma patients...
  74. ncbi Double coding and mapping using Abbreviated Injury Scale 1998 and 2005: identifying issues for trauma data
    Cameron S Palmer
    Trauma Service, Royal Children s Hospital Melbourne, Flemington Rd, Parkville 3052, Australia
    Injury 41:948-54. 2010
    ..The present study aimed to assess the potential impact of adopting the AIS05 codeset in an established trauma system, and to identify issues associated with this change...
  75. ncbi Low incidence of multiple organ failure after major trauma
    Sven Laudi
    Department of Anesthesiology and Intensive Care Medicine, University of Leipzig Medical Faculty, 04103 Leipzig, Germany
    Injury 38:1052-8. 2007
    ..The purpose of this study was to determine if incidence of organ failure and mortality in multiple trauma patients can be reduced by implementation of lung-protective strategies...
  76. ncbi The use of Trauma Score-Injury Severity Score (TRISS) at Siriraj Hospital: how accurate is it?
    Preecha Siritongtaworn
    Department of Surgery, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand
    J Med Assoc Thai 92:1016-21. 2009
    Trauma Score-Injury Severity Score (TRISS) is one of the most universally deployed scores. It is based on both the physiologic Revised Trauma Score (RTS) and anatomic Injury Severity Score (ISS)...
  77. ncbi Initial clinical experience with a 64-MDCT whole-body scanner in an emergency department: better time management and diagnostic quality?
    Michael Rieger
    Department of Radiology, Innsbruck Medical University, Innsbruck, Austria
    J Trauma 66:648-57. 2009
    ..The objective of this study was to assess time management and diagnostic quality when using a 64-multidetector-row computed tomography (MDCT) whole-body scanner to evaluate polytraumatized patients in an emergency department...
  78. ncbi Acute coagulopathy of trauma: mechanism, identification and effect
    Karim Brohi
    Department of Surgery, The Royal London Hospital, London, UK
    Curr Opin Crit Care 13:680-5. 2007
    ..Developing early in the postinjury phase, it is associated with increased transfusion requirements and poor outcomes. This review examines the possible initiators, mechanism and clinical importance of acute coagulopathy...
  79. pmc Association between a single-pass whole-body computed tomography policy and survival after blunt major trauma: a retrospective cohort study
    Martin Hutter
    Department of Trauma and Orthopedic Surgery, Berufsgenossenschaftliche Unfallklinik Murnau, Prof Küntscher Str 8, 82418 Murnau, Germany
    Scand J Trauma Resusc Emerg Med 19:73. 2011
    ..We hypothesized that a liberal pan-scan policy is mainly an indicator of enhanced process quality of emergency care that may lead to improved survival regardless of the actual use of the method...
  80. ncbi The Injury Severity Score or the New Injury Severity Score for predicting intensive care unit admission and hospital length of stay?
    Andre Lavoie
    Unité de recherche en traumatologie, Centre Hospitalier Affilié Universitaire de Québec Enfant Jésus Hospital, 1401, 18ème rue, Quebec City QC, Que, Canada G1J 1Z4
    Injury 36:477-83. 2005
    To compare the New Injury Severity Score (NISS) and the Injury Severity Score (ISS) as predictors of intensive care unit (ICU) admission and hospital length of stay (LOS) in an urban North American trauma population and in a subset of ..
  81. ncbi Is interleukin 6 an early marker of injury severity following major trauma in humans?
    F Gebhard
    Department of Traumatology, Hand and Reconstructive Surgery, University of Ulm, Germany
    Arch Surg 135:291-5. 2000
    ..Therefore, we designed a prospective study starting as early as at the scene of the unintentional injury, to determine the trauma-related release of plasma IL-6 in multiple injured patients...
  82. ncbi [Cost analysis of acute therapy of polytrauma patients]
    D Ganzoni
    Departement für Chirurgie, Klinik für Unfallchirurgie, Universitatsspital Zurich
    Swiss Surg 9:268-74. 2003
    ..We analysed the exact treatment costs of 16 patients with an average Injury Severity Score (ISS) of 33.9...
  83. ncbi Child and youth traffic-related injuries: use of a trauma registry to identify priorities for prevention in the United Arab Emirates
    Michal Grivna
    Institute of Public Health, College of Medicine and Health Sciences, United Arab Emirates University, Al Ain, United Arab Emirates
    Traffic Inj Prev 14:274-82. 2013
    ....
  84. ncbi Lung Organ Failure Score (LOFS): probability of severe pulmonary organ failure after multiple injuries including chest trauma
    Sebastian Wutzler
    Department of Trauma, Hand and Reconstructive Surgery, Hospital of the Johann Wolfgang Goethe University, Frankfurt, Germany
    Injury 43:1507-12. 2012
    ..Pulmonary complications are common in multiple trauma patients with chest injury. Factors predisposing these critically ill patients to respiratory organ failure are not fully understood...
  85. ncbi Inefficiencies in a rural trauma system: the burden of repeat imaging in interfacility transfers
    Rajan Gupta
    Department of Surgery, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    J Trauma 69:253-5. 2010
    ..This study was performed to examine how frequently computed tomography (CT) scans were repeated in interfacility transfers in a rural trauma system and to identify the most common reason for repeating the studies...
  86. ncbi Prediction of mortality in pediatric trauma patients: new injury severity score outperforms injury severity score in the severely injured
    Thomas Sullivan
    Department of Surgery, New York Medical College, Valhalla, 10595, USA
    J Trauma 55:1083-7; discussion 1087-8. 2003
    The Injury Severity Score (ISS) is a widely accepted method of measuring severity of traumatic injury. A modification has been proposed--the New Injury Severity Score (NISS)...
  87. ncbi Correlation of revised trauma score and injury severity score (TRISS) predicted probability of survival with peer-reviewed determination of trauma deaths
    Christina M Shanti
    Department of Surgery, Detroit Receiving Hospital, 6C University Health Center, Detroit, Michigan 48201, USA
    Am Surg 69:257-60; discussion 260. 2003
    ..deaths (PRDs) as determined by our review committee and correlate them with the Revised Trauma Score and Injury Severity Score (TRISS) probability of survival (PS). A total of 10,002 patients were identified...
  88. ncbi Use of leukoreduced blood does not reduce infection, organ failure, or mortality following trauma
    Michael S Englehart
    Department of Surgery, Oregon Health and Science University, 3181 SW Sam Jackson Road L223A, Portland, OR 97239, USA
    World J Surg 33:1626-32. 2009
    ..The objective of the present study was to determine the effect of LR blood on morbidity and mortality. We hypothesized that the use of LR blood does not improve outcome in trauma patients...
  89. ncbi The adoption of a new classification system: time-dependent variation in interobserver reliability of the thoracolumbar injury severity score classification system
    Alpesh A Patel
    Department of Orthopaedic Surgery, University of Utah, Salt Lake City, UT 84108, USA
    Spine (Phila Pa 1976) 32:E105-10. 2007
    ..Prospective clinical assessment of the interobserver reliability of the Thoracolumbar Injury Classification and Severity Score (TLISS) in a series of consecutive patients...
  90. ncbi The relationship between serious injury and blood alcohol concentration (BAC) in fatal motor vehicle accidents: BAC = 0.01% is associated with significantly more dangerous accidents than BAC = 0.00%
    David P Phillips
    Department of Sociology, University of California at San Diego, San Diego, CA 92093 0533, USA
    Addiction 106:1614-22. 2011
    ..To analyze the severity of automotive injuries associated with blood alcohol concentration (BAC) in increments of 0.01%...
  91. ncbi Trauma mortality in mature trauma systems: are we doing better? An analysis of trauma mortality patterns, 1997-2008
    Richard P Dutton
    Program in Trauma, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Trauma 69:620-6. 2010
    ..We examined injury severity, mortality, and preventability in a mature trauma system during a 12-year period to assess the overall benefits of these and other improvements...
  92. ncbi Outcomes and costs of penetrating trauma injury in England and Wales
    Michael C Christensen
    Global Development, Novo Nordisk A S, Krogshøjvej 55, DK 2880 Bagsvaerd, Denmark
    Injury 39:1013-25. 2008
    ..Little information exists on the patient and treatment characteristics for penetrating trauma in England and Wales, and the acute outcomes and costs of care have not been documented and analysed in detail...
  93. ncbi Level I versus Level II trauma centers: an outcomes-based assessment
    Michael T Cudnik
    Department of Emergency Medicine, The Ohio State University, Columbus, Ohio, USA
    J Trauma 66:1321-6. 2009
    ..Level II hospitals) remains unclear. We sought to determine whether there was a difference in the patient outcome in trauma victims taken to Level I versus Level II trauma centers...
  94. ncbi A simple tool for mortality prediction in burns patients: APACHE III score and FTSA
    E C Moore
    Victorian Adult Burns Service, The Alfred Hospital, Commercial Rd, Prahran, 3181, Melbourne, Australia
    Burns 36:1086-91. 2010
    ..85, 95% CI 0.79-0.92). Likelihood of death for patients with severe thermal injury can be predicted with accuracy from APACHE III-j score and percent FTSA. Prospective validation of our model on different burn populations is necessary...
  95. ncbi Use of scene vital signs improves TRISS predicted survival in intubated trauma patients
    Igor V Voskresensky
    Department of Surgery, Vanderbilt University School of Medicine, Nashville, Tennessee 37212, USA
    J Surg Res 154:105-11. 2009
    The Trauma Related Injury Severity Score (TRISS) has been previously validated to predict outcomes in nonintubated, nonparalyzed trauma patients...
  96. ncbi Comparison of the new injury severity score and the injury severity score in multiple trauma patients
    Xiao Gang Zhao
    Department of Emergency Medicine, Second Affiliated Hospital, Medical School of Zhejiang University, Hangzhou 310009, China
    Chin J Traumatol 11:368-71. 2008
    ..of less misclassification and greater area under receiver operator characteristic (ROC) curve of the new injury severity score (NISS) are better than the injury severity score (ISS) as applying it to our multiple trauma patients ..
  97. ncbi Incorporating recent advances to make the TRISS approach universally available
    Patrick D Kilgo
    Department of Biostatistics, Emory University School of Public Health, GA 30322, USA
    J Trauma 60:1002-8; discussion 1008-9. 2006
    The Trauma and Injury Severity Score (TRISS), used to garner predictions of survival from the Injury Severity Score (ISS), the Revised Trauma Score (RTS, for physiologic reserve), and age is difficult for many trauma facilities to ..
  98. ncbi Randomized clinical trial comparing the effect of computed tomography in the trauma room versus the radiology department on injury outcomes
    T P Saltzherr
    Trauma Unit, Department of Surgery, Biostatistics and Bioinformatics, Academic Medical Centre, Amsterdam, The Netherlands
    Br J Surg 99:105-13. 2012
    ..It was hypothesized that CT in the trauma room would improve patient outcome and workflow...
  99. ncbi Comparison of the Sequential Organ Failure Assessment, Acute Physiology and Chronic Health Evaluation II scoring system, and Trauma and Injury Severity Score method for predicting the outcomes of intensive care unit trauma patients
    Seong Youn Hwang
    Department of Emergency Medicine, Samsung Changwon Hospital, Sungkyunkwan University School of Medicine, Changwon 630 522, South Korea
    Am J Emerg Med 30:749-53. 2012
    ..Organ Failure Assessment (SOFA), Acute Physiology and Chronic Health Evaluation (APACHE) II scoring system, and Trauma and Injury Severity Score (TRISS) method to predict group mortality for intensive care unit (ICU) trauma patients.
  100. ncbi Long-term survival and return on investment after nonneurologic injury: implications for the elderly trauma patient
    Ben L Zarzaur
    Department of Surgery, University of Tennessee Health Science Center, Memphis, Tennessee 38163, USA
    J Trauma 69:93-8. 2010
    ..The purpose of this study was to evaluate the cost per 2-year survivor stratified by age after moderate- to severe-nonneurologic injury...
  101. ncbi Association of direct helicopter versus ground transport and in-hospital mortality in trauma patients: a propensity score analysis
    Kenneth E Stewart
    Emergency Systems Division, Oklahoma State Department of Health, University of Oklahoma Health Sciences Center, Oklahoma City, USA
    Acad Emerg Med 18:1208-16. 2011
    ..The aim of this study was to examine whether mode of transport (HEMS vs. ground EMS) is independently associated with mortality among trauma patients transported directly from the scene of injury to definitive care...

Research Grants67

  1. GM-CSF for Immunomodulation Following Trauma (GIFT) Trial
    Mark W Hall; Fiscal Year: 2013
    ..For all Aims of this project we will screen severely injured children (those with an Injury Severity Score >10) for innate immune suppression as defined by an ex vivo LPS-induced TNF1 production capacity <..
  2. Field Triage of Head Injured Older Adults Taking Anticoagulants or Platelet Inhib
    DANIEL KIDEN NISHIJIMA; Fiscal Year: 2013
    ..will be determined by the primary outcome of immediate tICH and the secondary outcomes of serious injury (Injury Severity Score greater than 15) and trauma center resource use (ICU admission, major non-orthopedic surgery, and/or in-..
  3. Study of EMS Findings Predictive of Pediatric Trauma Center Need
    E Brooke Lerner; Fiscal Year: 2011
    ..2, Aim 3: The individual components of the Field Triage Decision Scheme are predictive of a patient Injury Severity Score >15. Study Design: A prospective, 19-month observational study is proposed...
  4. BRIEF STRATEGIES--ALCOHOL RELATED NONTRAFFIC
    Janice Dyehouse; Fiscal Year: 1999
    ..Severity of injury will be assessed using the Trauma Score, the Injury Severity Score, and a Burn Severity Score...
  5. Are Volume Standards Accurate Measures of Quality?
    Laurent Glance; Fiscal Year: 2005
    ..abstract_text> ..
  6. The Effect of Hypertonic Resuscitation for Blunt Trauma
    Eileen Bulger; Fiscal Year: 2005
    ..abstract_text> ..
  7. Hypertonic Modulation of Inflammation following Injury
    Eileen M Bulger; Fiscal Year: 2010
    ..The results of these studies will provide valuable information to determine the ultimate therapeutic use of the resuscitation strategy. ..
  8. TRAUMA-RELATED ERYTHROPOIETIC SUPPRESSION
    David Livingston; Fiscal Year: 2003
    ..Understanding the mechanisms behind post-trauma anemia will allow therapeutic interventions improving endogenous erythropoiesis to be targeted. ..
  9. Evaluating Hospital Outcomes for Injured Patients
    David Clark; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  10. A PROSPECTIVE STUDY OF RISK OF MORTALITY AFTER SCI
    James Krause; Fiscal Year: 2002
    ..Risk profiles will be generated to identify individuals at greatest risk for early mortality. Separate analyses and risk profiles will be generated based on injury severity, gender and race/ethnicity. ..
  11. Integrating Well-Woman and Well-Baby Care to Improve Parenting & Family Wellness
    JOHN LEVENTHAL; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  12. Risk of Adverse Outcomes after Spinal Cord Injury: A Longitudinal Study
    James S Krause; Fiscal Year: 2010
    ..abstract_text> ..
  13. URBAN TRAUMA--HEALTH SERVICES AND EFFECTIVENESS TRIALS
    Douglas Zatzick; Fiscal Year: 2002
    ..The award provide support for ongoing development as an investigator, clinical, and educator so that the applicant may ultimately become a productive clinical- scientist in an academic department of psychiatry. ..
  14. Early Combined Intervention After Traumatic Injury
    Douglas F Zatzick; Fiscal Year: 2010
    ..abstract_text> ..
  15. Feasibility Study of Soccer Injuries
    Melissa Schiff; Fiscal Year: 2007
    ..Findings from this research will be used to for the development of a large, prospective cohort study to evaluate potentially modifiable risk factors for injury among female youth soccer players. [unreadable] [unreadable]..
  16. Cellular Signaling Mechanisms in Macrophage Activation.
    Joseph Cuschieri; Fiscal Year: 2007
    ..Through an enhanced understanding of these mechanisms it is our goal that potential therapeutic targets may be discovered to regulate the inflammatory response following trauma/hemorrhage and ischemia/reperfusion. ..
  17. A NEURAL NETWORK APPROACH TO PEDIATRIC TRAUMA TRIAGE
    RANDALL BURD; Fiscal Year: 2004
    ..The classification accuracy of trained networks will be compared with that based on current triage strategies. The long-term goal of this project is to develop and implement a tool for triaging injured children based on neural networks. ..
  18. Injury from Sexual Assault: Addressing Health Disparity
    Marilyn S Sommers; Fiscal Year: 2010
    ..Public Health Relevance: Violence against women is a silent epidemic. The forensic exam used to collect evidence after rape needs to be equally sensitive for females with dark skin as well as females with light skin. ..
  19. GLUCOSE-6-PHOSPHATE DEHYDROGENASE DEFICIENCY AND SEPSIS
    Zoltan Spolarics; Fiscal Year: 2004
    ..abstract_text> ..
  20. STUDY OF FUNCTIONAL OUTCOME AFTER TRAUMA IN ADOLESCENTS
    Troy Holbrook; Fiscal Year: 2002
    ..The true efficacy of trauma care systems in this country can only be demonstrated by addressing whether these systems return trauma victims to active functional roles in society. ..
  21. Combined Intercostal and Diaphragm Pacing
    Anthony DiMarco; Fiscal Year: 2004
    ....
  22. Erythrocytes, immuno-modulation and G6PD deficiency
    Zoltan Spolarics; Fiscal Year: 2007
    ..Elucidation of macrophage and T-cell cytokine responses to infection in G6PD deficiency may also be important in providing a mechanism of malaria protection alternative to currently accepted notions. [unreadable] [unreadable]..
  23. Trauma Center Brief Alcohol Treatments and Cost Effectivenes
    Thomas J Esposito; Fiscal Year: 2010
    ..New knowledge of the effectiveness, benefits and costs of these two Bl approaches would allow surgeons and trauma centers to make informed choices about alcohol interventions in trauma settings. ..
  24. Spinal Cord Stimulation to Restore Cough In Humans
    Anthony DiMarco; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  25. EXPIRATORY MUSCLE ACTIVATION TO PRODUCE COUGH
    Anthony DiMarco; Fiscal Year: 2003
    ..Restoration of affective cough mechanism may allow patients with spinal cord injury to clear secretions more easily, reduce the incidence of respiratory complication and, ultimately, improve their life quality. ..
  26. Back Disorders in Union Carpenters
    Hester Lipscomb; Fiscal Year: 2006
    ..The project addresses a number of areas of expressed interest to NIOSH including construction workers, back disorders, surveillance methods and health services research. [unreadable] [unreadable]..
  27. BACTERIAL MEMBRANE PROTEINS IN GRAM-NEGATIVE SEPSIS
    H Warren; Fiscal Year: 2008
    ..The experiments are designed to evaluate the importance that physiologically relevant forms of MLP and PAL play in the pathophysiology of sepsis during infection. ..
  28. Diffuse optical imaging of intracranial pressure changes
    Gary Strangman; Fiscal Year: 2004
    ....
  29. EMERGENCY DEPARTMENT OVERCROWDING AND QUALITY OF ACUTE ASTHMA CARE FOR CHILDREN
    Marion Sills; Fiscal Year: 2008
    ..Because the study centers on a priority population-children-it also [unreadable] addresses the AHRQ mission of assessing the quality of care for vulnerable populations. [unreadable] [unreadable] [unreadable] [unreadable]..
  30. Pharmacological fMRI to Identify New Anxiolytics: A Human Bioassay
    Murray Stein; Fiscal Year: 2008
    ..Enhancing the development of new treatments for anxiety is a public health priority. The projects proposed in this application have the potential to achieve this important aim. [unreadable] [unreadable] [unreadable]..
  31. OUTCOMES FOLLOWING LIMB RECONSTRUCTION VS AMPUTATION
    Ellen Mackenzie; Fiscal Year: 2003
    ..In addition, they propose to extend analysis of the 2-year data to address several important clinical and methodological issues. ..
  32. Improving Trauma Outcomes:A Patient Centered Approach
    Ellen Mackenzie; Fiscal Year: 2008
    ..unreadable]..
  33. DYNAMIC FEEDBACK CONTROL OF THE GH AXIS
    LEON FARHI; Fiscal Year: 2004
    ..abstract_text> ..
  34. ACTIVITY-DEPENDENT PLASTICITY AFTER SPINAL CORD INJURY
    Andrea Behrman; Fiscal Year: 2004
    ..abstract_text> ..
  35. 'Costs & Effectiveness of Trauma Care in the Elderly'
    Ellen Mackenzie; Fiscal Year: 2004
    ....
  36. Preventing Pressure Ulcers: A Multi-site RCT in Nursing Facilities
    NANCY I BERGSTROM; Fiscal Year: 2010
    ..Less frequent repositioning would allow residents longer periods of sleep, would reduce staff time for repositioning, and allow more efficient allocation of time. ..
  37. Susceptibility Weighted Imaging (SWI)
    EWART MARK HAACKE; Fiscal Year: 2010
    ..Recently, SWI has also become available to the clinical world for every day use and therefore its continued technical development is of paramount importance for the proper diagnosis of these diseases in patients. ..
  38. SYMPATHETIC FIBER MODULATION OF NEUROGENIC INFLAMMATION
    Kenneth Hargreaves; Fiscal Year: 2003
    ....
  39. ALCOHOL ABUSE AND DEPENDENCE IN TRAUMA PATIENTS
    Patricia Dischinger; Fiscal Year: 2002
    ..The validity of self reports will be assessed by interviewing collaterals from 100 randomly selected patients in each of the intervention and control groups at 6 and 12 months. ..
  40. Acupuncture for treatment of acute spinal cord injury
    Amitabh Jha; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  41. PS06-003, Opt-out HIV Testing in Emergency Dept settings
    Jason Haukoos; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  42. VENTILATOR-ASSOCIATED ALVEOLAR EPITHELIAL INJURY
    James Frank; Fiscal Year: 2006
    ..This research and comprehensive career development plan will prepare me to become an independent investigator in the mechanisms of alveolar epithelial injury and ventilator-associated lung injury. ..
  43. Gut Ischemia/Reperfusion Injury: Modulation by Nutrients
    Rosemary Kozar; Fiscal Year: 2006
    ..The sponsors are an integral part of this arrangement and are especially suited to ensure success of the proposed project...
  44. Prevention Unintentional Mechanical Birth Injuries
    Edith Gurewitsch; Fiscal Year: 2006
    ..to conduct a small, randomized clinical trial comparing clinician-applied forces following McRoberts' maneuver (a maternal manipulation) and following Rubin's maneuver (a fetal manipulation). ..
  45. Evaluation of New Imaging Methodologies at 7T
    EWART HAACKE; Fiscal Year: 2007
    ..Many of the approaches developed and applied on this animal system are expected to have important clinical impact. All of these projects will substantially benefit from the proposed acquisition. [unreadable] [unreadable] [unreadable]..
  46. Major Depression Following Minor Injury
    Therese Richmond; Fiscal Year: 2006
    ..Minor injury will be defined by the Injury Severity Score for anatomic severity and the triage-Revised Trauma Score for physiologic severity...
  47. Hemorrhagic Shock and Pancreatic Enzyme Products
    David Hoyt; Fiscal Year: 2007
    ..The results of this research provide not only an approach to examine the different enzymatic and inflammatory processes in hemorrhagic shock but also to directly serve as the basis for possible intervention in patients. ..
  48. Work-related Injuries Among Immigrant Workers
    Huiyun Xiang; Fiscal Year: 2008
    ..unreadable] [unreadable]..
  49. Cognitive Recovery after Traumatic Brain Injury
    Maureen Schmitter Edgecombe; Fiscal Year: 2007
    ....
  50. Diffuse optical brain imaging for stroke rehabilitation
    Gary Strangman; Fiscal Year: 2007
    ..Importantly, use of the DOT technology in such a research program is expected to enable the investigation of tasks and populations that are otherwise beyond the reach of existing brain imaging technologies. [unreadable] [unreadable]..
  51. Work injury and young people: A prospective survey
    F Breslin; Fiscal Year: 2005
    ..No study to date has examined the impact of work injuries on earnings losses among young workers, thereby addressing a notable gap in this research area. ..
  52. Mechanisms of Nicotine Induced Neurogenic Inflammation
    Kenneth Hargreaves; Fiscal Year: 2005
    ....
  53. Reducing the Disproportionate Burden of Orofacial Injury
    Vivek Shetty; Fiscal Year: 2007
    ..abstract_text> ..
  54. Epidemiology of Traumatic Brain Injury
    Jeffrey Bazarian; Fiscal Year: 2005
    ....
  55. OPTIMAL PREHOSPITAL CARE OF CHILDHOOD CARDIAC ARREST
    Ian Stiell; Fiscal Year: 2004
    ..The PIs propose to conduct a large feasibility review in five urban areas and to conduct four study planning workshops. ..
  56. Physical Work Capacity After Traumatic Brain Injury
    KURT MOSSBERG; Fiscal Year: 2009
    ..The latter is of particular importance from a public health perspective since the individual with TBI is usually young and will endure the permanent disabling effects of TBI for many years. ..
  57. IMPROVING CARE FOR PANIC DISORDER IN PRIMARY CARE
    Murray Stein; Fiscal Year: 2002
    ..abstract_text> ..
  58. MEDICATION ADHERENCE INTERVENTION FOR HIV+ PERSONS
    Debra Murphy; Fiscal Year: 2002
    ....
  59. Ventilator-Induced Lung Injury:Mechanisms & Consequences
    Scott Sinclair; Fiscal Year: 2005
    ..Aim 3A: Document cyclical airway collapse and reopening via changes in regional ventilation distribution. Aim 3B: Validate a method to estimate appropriate PEEP level to prevent cyclical airway collapse. ..
  60. Preventing Psychiatric Sequelae of Traumatic Injury
    Murray Stein; Fiscal Year: 2003
    ..Findings will provide justification for and information about optimal parameters (e.g., subject selection; sample size; dose and duration) for a future randomized controlled trial (RCT). ..
  61. Self-Regulation in Co-Occurring TBI and Substance Abuse
    Jennifer Bogner; Fiscal Year: 2006
    ..abstract_text> ..
  62. Maternal HIV: Intervention to Assist Disclosure to Children
    Debra Murphy; Fiscal Year: 2009
    ..Few interventions, other than for prevention or medication adherence, are available for women living with HIV;this study will evaluate an intervention that will help HIV-positive mothers deal with a serious family issue. ..
  63. Improving Outcomes in Pharmacotherapy of Social Phobia
    Murray Stein; Fiscal Year: 2009
    ..It thus directly addresses a critical public health issue that adversely affects a substantial proportion of the population. ..