Genomes and Genes
glasgow outcome scale
Summary: A scale that assesses the outcome of serious craniocerebral injuries, based on the level of regained social functioning.
Publications262 found, 100 shown here
- Reliability of postal questionnaires for the Glasgow Outcome ScaleJ T L Wilson
Department of Psychology, University of Stirling, Stirling, United Kingdom
J Neurotrauma 19:999-1005. 2002..study was to investigate if a questionnaire sent by mail can give a reliable assessment of outcome on the Glasgow Outcome Scale. A questionnaire was developed for the Glasgow Outcome Scale (GOS) and a second questionnaire for the ..
- Pressure reactivity as a guide in the treatment of cerebral perfusion pressure in patients with brain traumaTim Howells
Department of Neurosurgery, Uppsala University Hospital, Uppsala, Sweden
J Neurosurg 102:311-7. 2005..One protocol was primarily oriented toward reducing intracranial pressure (ICP), and the other primarily on maintaining cerebral perfusion pressure (CPP)...
- Determinants of long-term functional consequences after major traumaHerman R Holtslag
Department of Rehabilitation, University Medical Center, The Netherlands
J Trauma 62:919-27. 2007..The purpose of this study was to describe the long-term functional consequences from major trauma and to quantify the effect of sociodemographic, injury-related, and physical determinants of its outcome...
- Adjustment for strong predictors of outcome in traumatic brain injury trials: 25% reduction in sample size requirements in the IMPACT studyAdrian V Hernandez
Department of Public Health, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
J Neurotrauma 23:1295-303. 2006..The primary outcome was the dichotomized Glasgow Outcome Scale at 6 months (favorable/unfavorable)...
- Functional outcome scales in traumatic brain injury: a comparison of the Glasgow Outcome Scale (Extended) and the Functional Status ExaminationAnne M Hudak
Department of Physical Medicine and Rehabilitation, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9055, USA
J Neurotrauma 22:1319-26. 2005..The most widely used of these measures, the Glasgow Outcome Scale (GOS) and the GOS-Extended (GOS-E), have been criticized as suffering from ceiling effects...
- Reliability of a telephone-based Glasgow Outcome Scale assessment using a structured interview in a heterogenous population of patients and examinersScott A LeGrand
Department of Anesthesia, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA
J Neurotrauma 24:1437-46. 2007A reliable telephone-based Glasgow Outcome Scale (GOS) assessment would be advantageous to both patients and investigators...
- Increased levels of serum MAP-2 at 6-months correlate with improved outcome in survivors of severe traumatic brain injuryStefania Mondello
University of Florida, Department of Anesthesiology, Gainesville, FL, USA
Brain Inj 26:1629-35. 2012..To evaluate microtubule-associated proteins (MAP-2), a dendritic marker of both acute damage and chronic neuronal regeneration after injury, in serum of survivors after severe TBI and examine the association with long-term outcome...
- Outcome measures for traumatic brain injuryDhaval Shukla
Department of Neurosurgery, National Institute of Mental Health and Neurosciences, Bangalore, India
Clin Neurol Neurosurg 113:435-41. 2011..A few, commonly used are Glasgow Outcome Scale (GOS) with or without extended scores, Disability Rating Scale (DRS), Functional Independence Measure (FIM)..
- Relating quality of life to Glasgow outcome scale health statesJennifer Kosty
Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania, USA
J Neurotrauma 29:1322-7. 2012..quality-of-life (QOL) values are available for intermediate outcomes, such as those described by the Glasgow Outcome Scale Extended (GOSE). Our objective was therefore to determine QOL for the health states described by the GOSE...
- Cerebrospinal fluid biomarkers versus glasgow coma scale and glasgow outcome scale in pediatric traumatic brain injury: the role of young age and inflicted injuryPaul M Shore
Department of Pediatrics, University of Texas Southwestern Medical Center, Division of Critical Care Services, Children s Medical Center of Dallas, 1935 Motor Street, Dallas, TX 73235, USA
J Neurotrauma 24:75-86. 2007The Glasgow Coma Scale (GCS) and Glasgow Outcome Scale (GOS) are widely used clinical scoring systems to measure the severity of neurologic injury after traumatic brain injury (TBI), but have recognized limitations in infants and small ..
- Outcomes of early endovascular versus surgical treatment of ruptured cerebral aneurysms. A prospective randomized studyT Koivisto
Departments of Neurosurgery, Kuopio University Hospital, Kuopio, Finland
Stroke 31:2369-77. 2000..This prospective study was conducted to compare the outcomes of surgical clipping and endovascular treatment in acute (<72 hours) aneurysmal subarachnoid hemorrhage (SAH)...
- IL-6 polymorphism associated with fatal outcome in patients with severe traumatic brain injuryAndré Luiz Dalla Libera
Programa de Pós Graduação em Genética e Toxicologia Aplicada, Universidade Luterana do Brasil ULBRA, Canoas, Brazil
Brain Inj 25:365-9. 2011....
- Prevalence and determinants of disabilities and return to work after major traumaWouter J Vles
Department of Surgery, St Elisabeth Hospital, Tilburg, The Netherlands
J Trauma 58:126-35. 2005..The purpose of this study was to assess the prevalence and determinants of disabilities and return to work after severe injury in a Dutch, Level I trauma center...
- Increased matrix metalloproteinase-9 in blood in association with activation of interleukin-6 after traumatic brain injury: influence of hypothermic therapyEiichi Suehiro
Department of Neurosurgery, Clinical Neuroscience, Yamaguchi University School of Medicine, Ube, Yamaguchi 755 8505, Japan
J Neurotrauma 21:1706-11. 2004..The elevation of MMP-9 is associated with inflammatory events following TBI. Hypothermic intervention may suppress the elevation of MMP-9 with suppression of the inflammatory response, affording neuroprotection in TBI...
- Anxiety and depression after spontaneous subarachnoid hemorrhagePaul Graham Morris
Section of Clinical and Health Psychology, University of Edinburgh, Edinburgh, Scotland
Neurosurgery 54:47-52; discussion 52-4. 2004..Relatively little attention has been paid to emotional outcome after subarachnoid hemorrhage (SAH). This study assessed levels of anxiety and depression among SAH survivors and related these to clinical indices...
- Glasgow Coma Scale, brain electric activity mapping and Glasgow Outcome Scale after hyperbaric oxygen treatment of severe brain injuryH Ren
Department of Neurosurgery, Second Affiliated Hospital, Lanzhou Medical Collage, Lanzhou 730030, China
Chin J Traumatol 4:239-41. 2001..alteration of clinic GCS (Glasgow Coma Scale), brain electric activity mapping (BEAM), prognosis and GOS (Glasgow Outcome Scale) before a nd after hyperbaric oxygen treatment...
- Basal ganglia haematomas in non-comatose patients: subacute stereotactic aspiration improves long-term outcome in comparison to purely medical treatmentGerhard Marquardt
Neurosurgical Clinic, Johann Wolfgang Goethe University, Schleusenweg 2 16, 60528, Frankfurt am Main, Germany
Neurosurg Rev 28:64-9. 2005..Compared with medical patients, the median Glasgow Outcome Scale score was 1 point higher (P<0...
- Design and analysis of phase III trials with ordered outcome scales: the concept of the sliding dichotomyGordon D Murray
Public Health Sciences, University of Edinburgh Medical School, Edinburgh, United Kingdom
J Neurotrauma 22:511-7. 2005..The approach raises issues of clinical, statistical, and regulatory importance, and we initiate what we believe needs to become a widespread debate amongst the community involved in clinical research in head injury and stroke...
- Frameless stereotactic aspiration and thrombolysis of deep intracerebral hemorrhage is associated with reduction of hemorrhage volume and neurological improvementPaul Vespa
University of California, Los Angeles, David Geffen School of Medicine, USA
Neurocrit Care 2:274-81. 2005..This is a phase-2 safety trial to demonstrate the ability of frameless stereotactic aspiration and thrombolysis of ICH to safely remove blood...
- Hybrid outcome prediction model for severe traumatic brain injuryBoon Chuan Pang
Acute Brain Injury Research Laboratory, Department of Neurosurgery, National Neuroscience Institute, 11 Jalan Tan Tock Seng, 308433 Singapore
J Neurotrauma 24:136-46. 2007..Combining both logistic regression and decision tree models, a hybrid prediction model was then developed. This hybrid model would more accurately predict the 6-month post-severe head injury outcome using baseline admission parameters...
- The impact of aneurysmal subarachnoid hemorrhage on functional outcomeCatherine J Kirkness
University of Washington, Box 357266, Seattle, WA 98195 7266, USA
J Neurosci Nurs 34:134-41. 2002..This article describes outcome at 3 months after aneurysmal SAH in 61 patients, using the Extended Glasgow Outcome Scale (GOSE) and the Functional Status Examination (FSE)...
- Glasgow Coma Scale on admission is correlated with postoperative Glasgow Outcome Scale in chronic subdural hematomaAbbass Amirjamshidi
Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
J Clin Neurosci 14:1240-1. 2007To evaluate the correlation between admission Glasgow Coma Scale (GCS) and Glasgow Outcome Scale (GOS) in chronic subdural hematoma (CSDH).
- Psychosocial functioning during the year following severe traumatic brain injuryD A Kersel
Department of Psychological Medicine, University of Glasgow, Scotland, UK
Brain Inj 15:683-96. 2001..There was also a significant and ongoing decrease in all five aspects of social and leisure activities...
- Predicting outcome after traumatic brain injury: development and validation of a prognostic score based on admission characteristicsChantal W P M Hukkelhoven
Center for Clinical Decision Sciences, Department of Public Health, Erasmus MC, Rotterdam, The Netherlands
J Neurotrauma 22:1025-39. 2005..evaluated mortality and unfavorable outcome, that is, death, and vegetative or severe disability on the Glasgow Outcome Scale (GOS), at 6 months post-injury...
- Epidemiology, severity classification, and outcome of moderate and severe traumatic brain injury: a prospective multicenter studyTeuntje M J C Andriessen
Department of Neurology, Radboud University Nijmegen Medical Center, Nijmegen, The Netherlands
J Neurotrauma 28:2019-31. 2011..Our results confirm that TBI epidemiology and injury patterns have changed in recent years whereas case fatality rates remain high...
- Early Glasgow Outcome Scale scores predict long-term functional outcome in patients with severe traumatic brain injuryJoseph T King
Section of Neurosurgery, VA Connecticut Healthcare System 112, West Haven, Connecticut 06516, USA
J Neurotrauma 22:947-54. 2005..We examined the association between Glasgow Outcome Scale (GOS) assessed at 3 months and long-term outcomes at 12 months after TBI...
- Validity and sensitivity to change of the extended Glasgow Outcome Scale in mild to moderate traumatic brain injuryH S Levin
Department of Physical Medicine and Rehabilitation, Baylor College of Medicine, Houston, Texas 77030, USA
J Neurotrauma 18:575-84. 2001Using a structured outcome interview, this study addressed the validity and sensitivity to change of the Glasgow Outcome Scale (GOS) and the Extended GOS (GOSE) in a prospective study of patients who sustained mild (n = 30) to moderate (..
- Use of the Oxford Handicap Scale at hospital discharge to predict Glasgow Outcome Scale at 6 months in patients with traumatic brain injuryPablo Perel
Department of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK
BMC Med Res Methodol 8:72. 2008..The Glasgow Outcome Scale (GOS) is the most widely used outcome measure in randomised controlled trials (RCTs) in TBI patients...
- Blood pressure and outcome after severe pediatric traumatic brain injuryMonica S Vavilala
Department of Anesthesiology, Harborview Medical Center, University of Washington, Seattle, USA
J Trauma 55:1039-44. 2003..We examined the relationship between age-appropriate systolic blood pressure (AASBP) percentile and outcome after severe pediatric TBI...
- Spectrin breakdown products in the cerebrospinal fluid in severe head injury--preliminary observationsO Farkas
Department of Neurosurgery, Center for Medical and Health Sciences, Pecs University, Pecs, Hungary
Acta Neurochir (Wien) 147:855-61. 2005....
- Association between interleukin-1 beta (IL-1beta) gene polymorphism and outcome after head injury: an early reportM Uzan
Department of Neurosurgery, Istanbul University Cerrahpasa Medical Faculty, Istanbul, Turkey
Acta Neurochir (Wien) 147:715-20; discussion 720. 2005..Therefore, the aim of this paper was to search for the possible association between the outcome and IL-1beta gene polymorphism in human HI...
- Intracranial hypertension: what additional information can be derived from ICP waveform after head injury?M Balestreri
Department of Neurosurgery, Addenbrooke s Hospital, Cambridge, UK
Acta Neurochir (Wien) 146:131-41. 2004..We have studied whether the value of ICP monitoring can be augmented by indices describing cerebrovascular pressure-reactivity and pressure-volume compensatory reserve derived from ICP and arterial blood pressure (ABP) waveforms...
- Hyperglycemia and outcomes from pediatric traumatic brain injuryAmalia Cochran
Department of Surgery, University of Utah, Salt Lake City, USA
J Trauma 55:1035-8. 2003..The clinical significance of hyperglycemia after pediatric traumatic brain injury is controversial. This study addresses the relationship between hyperglycemia and outcomes after traumatic brain injury in pediatric patients...
- Alteration in brain natriuretic peptide (BNP) plasma concentration following severe traumatic brain injuryG E Sviri
Department of Neurosurgery, Rambam Maimonides Medical Center, Technion Israel Institute of Technology, Haifa, Israel
Acta Neurochir (Wien) 148:529-33; discussion 533. 2006..The purpose of the present study was to evaluate trends in BNP plasma concentrations during the acute phase following severe (traumatic brain injury) TBI...
- Raised parenchymal interleukin-6 levels correlate with improved outcome after traumatic brain injuryCraig D Winter
Neurosurgical Department, Wessex Neurological Centre, Southampton, University Hospitals NHS Trust, School of Medicine, University of Southampton, SO16 7PX, UK
Brain 127:315-20. 2004..were assessed initially using the Glasgow coma score, and survivors were assessed after 6 months using the Glasgow outcome scale. Significantly (P = 0...
- Intracranial pressure levels and single wave amplitudes, Glasgow Coma Score and Glasgow Outcome Score after subarachnoid haemorrhageP K Eide
Department of Neurosurgery, The National Hospital, Rikshospitalet, Oslo, Norway
Acta Neurochir (Wien) 148:1267-75; discussion 1275-6. 2006..To relate intracranial pressure (ICP) levels and single ICP wave amplitudes to the acute clinical state (Glasgow Coma Score, GCS) and final clinical outcome (Glasgow Outcome Score, GOS) in patients with subarachnoid haemorrhage (SAH)...
- Increased serum-GFAP in patients with severe traumatic brain injury is related to outcomeK Nylen
Department of Neurology, Institute of Clinical Neuroscience, Sahlgrenska University Hospital, University of Goteborg, S 413 45 Goteborg, Sweden
J Neurol Sci 240:85-91. 2006..However, a more specific marker is required and glial fibrillary acidic protein (GFAP) is considered to be a good candidate...
- Superior orbital rim approach for anterior communicating artery aneurysms: a surgical series of 27 patientsByung Chan Jeon
Division of Minimally Invasive Neurosurgery, Kosin University Gospel Hospital, Busan, Korea
J Korean Med Sci 18:566-72. 2003..1%) were from 29 to 79 yr in age. The mean aneurysm size was 6.2 mm ranging from 4 to 12 mm. A favorable Glasgow outcome scale (GOS) of 4 or 5 was achieved in 92.6%, a GOS score of 3 in 3.7%, and 1 death (GOS 1) occurred in 3...
- Intracranial aneurysms in Sarawak General Hospital over a 30-month periodJ S Wong
Hospital Umum Sarawak, Jalan Tun Ahmad Zaidi Adruce, Kuching, Sarawak, Malaysia
J Clin Neurosci 11:254-8. 2004..Good results can be achieved in developing countries with early diagnosis and intensive management...
- Outcome of moderate and severe traumatic brain injury amongst the elderly in SingaporeB K Gan
Department of Neurosurgery, National Neuroscience Institute, Singapore
Ann Acad Med Singapore 33:63-7. 2004..In line with other established protocols, our unit has instituted a standardised protocol for the management of moderate and severe traumatic brain injury since 1996 in our neurointensive care unit...
- Endovascular treatment of posterior cerebral artery aneurysmsW J van Rooij
Department of Radiology, St Elisabeth Ziekenhuis, Tilburg, Netherlands
AJNR Am J Neuroradiol 27:300-5. 2006..The purpose of this study was to report the incidence, clinical presentation, endovascular treatment, and outcome of aneurysms of the posterior cerebral artery (PCA)...
- Absolutely no hope? Some ambiguity of futility of care in devastating acute strokeEelco F M Wijdicks
Neurological Neurosurgical Intensive Care Unit, Saint Marys, Mayo Clinic College of Medicine, Rochester, MN 55905, USA
Crit Care Med 32:2332-42. 2004..There has not been a critical review of the data used to make decisions of withdrawal of care in patients with severe strokes...
- Glial fibrillary acidic protein in serum after traumatic brain injury and multiple traumaLinda E Pelinka
Ludwig Boltzmann Institute for Experimental and Clinical Traumatology and Research Unit of the Austrian Worker s Compensation Board, Vienna, Austria
J Trauma 57:1006-12. 2004....
- Surgical management of ruptured and unruptured symptomatic posterior inferior cerebellar artery aneurysmsDonald Liew
Department of Neurosurgery, National Neuroscience Institute, Singapore
Br J Neurosurg 18:608-12. 2004..In aneurysms that cannot be clipped, sacrifice of the PICA without revascularisation procedures in proximally located PICA aneurysms may still be feasible if the occlusion is done distal to the perforators...
- Early decompressive craniectomy may be effective in the treatment of refractory intracranial hypertension after traumatic brain injuryV A Josan
Department of Paediatric Neurosurgery, Birmingham Children s Hospital, Steelhouse Lane, Birmingham, B4 6NH, UK
Childs Nerv Syst 22:1268-74. 2006..We compared the effect of early decompressive craniectomy (<24 h) vs non-operative treatment on the outcome of children with refractory intracranial hypertension after severe traumatic brain injury...
- Decompressive laparotomy to treat intractable intracranial hypertension after traumatic brain injuryD Andrea K Joseph
Program in Trauma, University of Maryland School of Medicine, Baltimore, Maryland 21201, USA
J Trauma 57:687-93; discussion 693-5. 2004..Recently, we noticed that abdominal fascial release could be useful in treating intracranial hypertension (ICH) after traumatic brain injury (TBI). We added this as an option in our treatment of TBI...
- Therapeutic hypothermia in traumatic brain injuryJoanna E Wright
Critical Care Services, Scripps Mercy Hospital, San Diego, CA 92103, USA
Crit Care Nurs Q 28:150-61. 2005..Also included is a review of 2 major randomized, controlled trials of hypothermia for traumatic brain injury that have been instrumental in establishing guidelines and directing further research...
- Traumatic brain injury: a reviewScot Nolan
Critical Care Department, Scripps Mercy Hospital, San Diego, CA 92103, USA
Crit Care Nurs Q 28:188-94. 2005..This article describes the classification, mechanism of injury, pathophysiology, and clinical therapeutic management strategies identified as best practice for TBI...
- [Functional outcome at discharge of patients with severe traumatic brain injury admitted to a brain damage unit]F Orient-López
Unidad de Daño Cerebral, Institut Guttmann, Hospital de Neurorehabilitació, Badalona, Barcelona, Spain
Rev Neurol 39:901-6. 2004....
- Decompressive craniectomy in traumatic brain injury: outcome following protocol-driven therapyI Timofeev
Department of Neurosurgery, Addenbrooke s Hospital, Cambridge, UK
Acta Neurochir Suppl 96:11-6. 2006..Outcome was assessed at an interval of at least 6 months following injury using the Glasgow Outcome Scale (GOS) score and the SF-36 quality of life questionnaire...
- Angiography and aneurysmsAlfonso Lagares
J Neurosurg 100:982-3; author reply 983-4. 2004
- Decompressive craniectomy in traumatic brain injury: the randomized multicenter RESCUEicp study (www.RESCUEicp.com)P J Hutchinson
Department of Neurosurgery, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
Acta Neurochir Suppl 96:17-20. 2006..We describe the concept of decompressive craniectomy in traumatic brain injury and the rationale and protocol of the RESCUEicp study...
- Predictive value of initial computerized tomography scan, intracranial pressure, and state of autoregulation in patients with traumatic brain injuryMagdalena Hiler
Academic Neurosurgical Unit, Department of Clinical Neuroscience, University of Cambridge, Addenbrooke s NHS Trust, Cambridge, United Kingdom
J Neurosurg 104:731-7. 2006....
- Neurologic outcome of posttraumatic refractory intracranial hypertension treated with external lumbar drainageJosep M Abadal-Centellas
Servicio de Medicina Intensiva, Hospital Universitario Son Dureta, Palma de Mallorca, Spain
J Trauma 62:282-6; discussion 286. 2007..The use of external lumbar drainage (ELD) has been described in these patients. We report our experience with the use of ELD in 17 cases of refractory ICH after severe TBI...
- Alpha-melanocyte-stimulating hormone is decreased in plasma of patients with acute brain injurySandra Magnoni
Department of Anesthesia and Intensive Care, Ospedale Maggiore di Milano IRCCS, Milano, Italy
J Neurotrauma 20:251-60. 2003..The data raise the possibility that restoration of normal circulating alpha-MSH through administration of the peptide could be beneficial in patients with brain injury...
- Angiographic follow-up of vertebrobasilar artery aneurysms treated with detachable coilsC Groden
Department of Neuroradiology, University Hospital Hamburg Eppendorf, Martinistrasse 52, 20251, Hamburg, Germany
Neuroradiology 45:435-40. 2003..Within the entire second observation period, three (5%) of the 59 patients had a further haemorrhage and were retreated with GDC. Rebleeding proved to be the only factor influencing the clinical outcome of retreated patients...
- Excitatory amino acid concentrations in ventricular cerebrospinal fluid after severe traumatic brain injury in infants and children: the role of child abuseR A Ruppel
Department of Anesthesiology, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA
J Pediatr 138:18-25. 2001..Young age and child abuse were associated with extremely high CSF glutamate concentrations after TBI. A possible role for excitotoxicity after pediatric TBI is supported...
- Posttraumatic rehabilitation and one year outcome following acute traumatic brain injury (TBI): data from the well defined population based German Prospective Study 2000-2002K R H von Wild
Medical Faculty, Westphälische Wilhelms University, Munster, Germany
Acta Neurochir Suppl 101:55-60. 2008..Early outcome after rehabilitation is assessed by the Glasgow Outcome Scale (GOS) score of patients following rehabilitation and of 63% of all TBI with the aid of follow-up ..
- The effect of haematoma, brain injury, and secondary insult on brain swelling in traumatic acute subdural haemorrhageS Sawauchi
Department of Neurosurgery, Jikei University School of Medicine, Tokyo, Japan
Acta Neurochir (Wien) 150:531-6; discussion 536. 2008..The purpose of this study was to investigate the pathophysiology of brain swelling associated with ASDH in traumatic brain injury...
- Time course of intracranial hypertension after traumatic brain injuryNino Stocchetti
Anesthesia and Intensive Care Medicine, Milan University, Neuroscience ICU, Fondazione IRCCS Ospedale Maggiore Policlinico, Mangiagalli, e Regina Elena, Milan, Italy
J Neurotrauma 24:1339-46. 2007..In these cases, HICP was significantly worse and required more intense therapies...
- Hyponatremia in patients with traumatic brain injury: incidence, mechanism, and response to sodium supplementation or retention therapy with hydrocortisoneNobuhiro Moro
Department of Neurological Surgery, Nihon University School of Medicine, Itabashi ku, Tokyo 173 8610, Japan
Surg Neurol 68:387-93. 2007..For sodium retention therapy, hydrocortisone was administered, expecting its mineralocorticoid effect, when the hyponatremia was associated with excess natriuresis...
- Impact of age on long-term recovery from traumatic brain injuryCarlos D Marquez de la Plata
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
Arch Phys Med Rehabil 89:896-903. 2008..To determine whether older persons are at increased risk for progressive functional decline after traumatic brain injury (TBI)...
- [Craniocerebral gunshot wounds: a study of outcome predictors]G Paradot
Service de neurochirurgie du Kremlin Bicêtre, 78, Avenue du General Leclerc, 94270 Le Kremlin Bicetre, France
Neurochirurgie 54:79-83. 2008..A retrospective study about craniocerebral gunshot wounds was done to better identify outcome predictors...
- The treatment of refractory intracranial hypertension and its control by means of external lumbar drainage (ELD)Hazem Akil
J Trauma 63:720-1; author reply 721. 2007
- [Idiopathic subarachnoid hemorrhage; comparison of different bleeding patterns and long-term outcome]A Lagares
Servicio de Neurocirugia, Hospital 12 de Octubre, Madrid
Neurocirugia (Astur) 13:110-9. 2002..This classification could permit the establishment of differences in the management and prognosis...
- Severe traumatic brain injury in children--are the results improving?Jurg Pfenninger
Pediatric Intensive Care Unit, University Children s Hospital, Inselspital, Bern, Switzerland
Swiss Med Wkly 132:116-20. 2002..Medical management is constantly being refined, and thus results should improve. The aim of the present study was to analyse our data of recent years and to compare them with previous series (1978-83 and 1988-92)...
- Significance of computed tomography mixed density in traumatic extra-axial hemorrhageS K Subramanian
Department of Radiology, Wayne State University School of Medicine, Detroit Receiving Hospital, Detroit, MI, USA
Neurol Res 24:125-8. 2002..Nevertheless, we conclude clinical exam and other published CT criteria are better indicators of injury severity and outcome...
- Curative effect of wilsonii injecta on severe head injuryLigang Chen
Department of Neurosurgery, General Hospital of Chengdu Military Command, Chengd u 610083, China
Chin J Traumatol 5:82-5. 2002..To study the curative effect of wilsonii injecta on severe head injury (SHI)...
- Endovascular treatment of ruptured intracranial aneurysms in patients aged 65 years and older: follow-up of 52 patients after 1 yearJ Sedat
Department of Interventional Neuroradiology, Centre Hospitalier Universitaire Nice, Nice, France
Stroke 33:2620-5. 2002..We compared endovascular therapy results in patients aged > or =65 and <65 years...
- Continuation of poor surgical outcome after elderly brain injurySandeep Mohindra
Department of Neurosurgery, Postgraduate Institute of Medical Education and Research, Chandigarh, India
Surg Neurol 69:474-7. 2008..In spite of the decline in mortality among trauma patients, with advanced trauma care, the outcome for elderly patients remains poor. Both operative and nonoperative outcome for elderly patients after head trauma has resisted improvement...
- Severe traumatic brain injury in Austria V: CT findings and surgical managementJohannes Leitgeb
University Department of Trauma Surgery, General Hospital Vienna, Vienna, Austria
Wien Klin Wochenschr 119:56-63. 2007..The aim of this paper is to describe CT findings and surgical management of patients with severe traumatic brain injury (TBI) in Austria...
- Severe head injury in early infancy: analysis of causes and possible predictive factors for outcomeElisabetta Marton
Neurosurgery Department, Padova University, Ca Foncello Hospital, 31100 Treviso, Italy
Childs Nerv Syst 23:873-80. 2007..The aim of this study was to analyse the causes and prognostic factors for outcome in severe traumatic brain injuries (TBI) in early infancy...
- Diffuse alterations in synaptic protein expression following focal traumatic brain injury in the immature ratG T Gobbel
Department of Neurological Surgery, University of Pittsburgh, Suite B 400, UPMC Presbyterian, 200 Lothrop Street, Pittsburgh, PA 15213, USA
Childs Nerv Syst 23:1171-9. 2007..The present study examined the potential role of synaptic alterations in this process by using an animal model of immature head injury to define the impact of TBI on expression of the synaptic protein, synaptophysin...
- Traumatic acute subdural haematomas of the posterior fossa: clinicoradiological analysis of 24 patientsD D'Avella
Clinica Neurochirurgica, Universita di Messina, Messina, Italy
Acta Neurochir (Wien) 145:1037-44; discussion 1044. 2003..We report 24 patients with a traumatic acute subdural haematoma of the posterior fossa managed between 1997 and 1999 at 8 Italian neurosurgical centres...
- [Subarachnoid hemorrhage without aneurysm]W Muller-Forell
Institut für Neuroradiologie des Universitätsklinikums Mainz, Germany
Radiologe 42:871-9. 2002....
- Relatives' reports of long term problems following traumatic brain injury or subarachnoid haemorrhageD J Hellawell
Rehabilitation Studies Unit, The University of Edinburgh, UK
Disabil Rehabil 23:300-5. 2001..The Glasgow Outcome Scale (GOS) and the Relative's Questionnaire (RQ) were used...
- Predictive value of initial clinical status, intracranial pressure and transcranial Doppler pulsatility after subarachnoid haemorrhageM Soehle
Department of Anaesthesiology and Intensive Care Medicine, University of Bonn, Bonn, Germany
Acta Neurochir (Wien) 149:575-83. 2007....
- Intracranial pressure and cerebral perfusion pressure as risk factors in children with traumatic brain injuriesAlbert Català-Temprano
Pediatric Intensive Care Unit, Pediatrics Department, Integrated Unit Sant Joan de Déu Clínic, Hospital Universitari Sant Joan de Deu, Universitat de Barcelona, Esplugues, Barcelona, Spain
J Neurosurg 106:463-6. 2007..The authors evaluated the initial intracranial pressure (ICP) and cerebral perfusion pressure (CPP) as prognostic factors in severe head injury in children and tried to determine the optimal CPP range...
- Does intensive rehabilitation improve the functional outcome of patients with traumatic brain injury (TBI)? A randomized controlled trialX L Zhu
Division of Neurosurgery, Department of Surgery, Prince of Wales Hospital, Chinese University of Hong Kong, Hong Kong, PR China
Brain Inj 21:681-90. 2007..To evaluate the effects of an increase in the intensity of rehabilitation on the functional outcome of patients with traumatic brain injury (TBI)...
- Increases in cerebrospinal fluid caffeine concentration are associated with favorable outcome after severe traumatic brain injury in humansKathleen T Sachse
Department of Critical Care Medicine, Safar Center for Resuscitation Research, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15260, USA
J Cereb Blood Flow Metab 28:395-401. 2008..Demographics, Glasgow Coma Scale (GCS) score, admission blood alcohol level, and 6-month dichotomized Glasgow Outcome Scale (GOS) score were assessed. Mean time from injury to initial CSF sampling was 10.77+/-3.13 h...
- Effects of fentanyl and S(+)-ketamine on cerebral hemodynamics, gastrointestinal motility, and need of vasopressors in patients with intracranial pathologies: a pilot studyMarc D Schmittner
Department of Anesthesiology and Critical Care Medicine, University Hospital Mannheim, University of Heidelberg, Mannheim, Germany
J Neurosurg Anesthesiol 19:257-62. 2007..Our results indicate that S(+)-ketamine does not increase ICP and that its use in neurosurgical patients should not be discouraged on the basis of ICP-related concerns...
- Multiple interstitial substances measured by microdialysis in patients with subarachnoid hemorrhageF Staub
Department of Neurosurgery, University of Cologne, Germany
Neurosurgery 47:1106-15; discussion 1115-6. 2000....
- Attenuated cerebrospinal fluid leukocyte count and sepsis in adults with pneumococcal meningitis: a prospective cohort studyMartijn Weisfelt
Department of Neurology, Centre of Infection and Immunity Amsterdam CINIMA, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands
BMC Infect Dis 6:149. 2006..Whereas a low CSF WBC indicates the presence of sepsis with early meningitis in patients with meningococcal infections, the relation between CSF WBC and outcome in patients with pneumococcal meningitis is not understood...
- Differential responses in three thalamic nuclei in moderately disabled, severely disabled and vegetative patients after blunt head injuryWilliam L Maxwell
Laboratory of Human Anatomy, Thomson Building, Institute of Biomedical and Life Sciences, University of Glasgow, Glasgow G12 8QQ, UK
Brain 127:2470-8. 2004..the dorsomedial, ventral posterior and lateral posterior thalamic nuclei in patients assessed by the Glasgow Outcome Scale as moderately disabled (n = 9), severely disabled (n = 12) and vegetative (n = 10) head-injured patients ..
- Clinical features and prognostic factors in adults with bacterial meningitisDiederik van de Beek
Department of Neurology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands
N Engl J Med 351:1849-59. 2004..We conducted a nationwide study in the Netherlands to determine clinical features and prognostic factors in adults with community-acquired acute bacterial meningitis...
- Role of decompressive craniectomy in the management of severe head injury with refractory cerebral edema and intractable intracranial pressure. Our experience with 48 casesSalvatore Chibbaro
Department of Neurosurgery, University Hospital, 34100 Trieste, Italy
Surg Neurol 68:632-8. 2007..Only very few randomized studies relating to this topic exist in the literature, including a very small number of patients with no class I evidence...
- Effects of tissue plasminogen activator for acute ischemic stroke at one year. National Institute of Neurological Disorders and Stroke Recombinant Tissue Plasminogen Activator Stroke Study GroupT G Kwiatkowski
Department of Emergency Medicine, Long Island Jewish Medical Center, New Hyde Park, NY 11040, USA
N Engl J Med 340:1781-7. 1999..It was unknown, however, whether the benefit would be sustained for longer periods...
- Influence of blood pressure variability on short-term outcome in patients with subarachnoid hemorrhageK Beseoglu
Heinrich Heine Universitat, Neurochirurgische Klinik, Dusseldorf, Germany
Cent Eur Neurosurg 71:69-74. 2010..The present study was conducted to evaluate the effect of blood pressure, intracranial pressure and cerebral perfusion pressure variation on short-term outcome in patients after severe subarachnoid hemorrhage (SAH)...
- Amantadine to improve neurorecovery in traumatic brain injury-associated diffuse axonal injury: a pilot double-blind randomized trialJay M Meythaler
Department of Physical Medicine and Rehabilitation, Spain Rehabilitation Center R157, School of Medicine, University of Alabama at Birmingham, 619 6th Avenue, Birmingham, AL 35249 7330, USA
J Head Trauma Rehabil 17:300-13. 2002..Because of its affect on both dopamine and N-methyl-D-aspartate (NMDA) channels, amantadine has been the subject of considerable interest and clinical use in acute TBI...
- The role of hypothermia in the management of severe brain injury: a meta-analysisOdette A Harris
Department of Neurosurgery, Stanford University Medical Center, 300 Pasteur Dr, Edwards Bldg, Second Floor, Stanford, CA 94305, USA
Arch Neurol 59:1077-83. 2002..Hypothermia is utilized in the management of severe traumatic brain injury despite the lack of unequivocal evidence supporting its use. Because of its widespread use, the effects of hypothermia are a concern...
- Incidence and prognostic significance of fever following intracerebral hemorrhageS Schwarz
Department of Neurology, University of Heidelberg, Germany
Neurology 54:354-61. 2000..To investigate the incidence and prognostic significance of fever on presentation and during the subsequent 72 hours in patients with spontaneous supratentorial intracerebral hemorrhage (ICH)...
- Effects of intraoperative hypothermia on neuropsychological outcomes after intracranial aneurysm surgerySteven W Anderson
Department of Neurology, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA
Ann Neurol 60:518-27. 2006..improve neurological outcome in good-grade surgical subarachnoid hemorrhage patients, as assessed by the Glasgow Outcome Scale score or other neurological and functional measures (National Institutes of Health Stroke Scale, Rankin ..
- Immediate administration of tranexamic acid and reduced incidence of early rebleeding after aneurysmal subarachnoid hemorrhage: a prospective randomized studyJan Hillman
Neurosurgical Department, University Hospital Linkoping, University Hospital Lund, Sweden
J Neurosurg 97:771-8. 2002..The object of this randomized, prospective, multicenter study was to assess the efficacy of short-term antifibrinolytic treatment with tranexamic acid in preventing rebleeding...
- Post-operative hematoma after surgery for intracranial meningiomas: causes, avoidable risk factors and clinical outcomeRüdiger Gerlach
Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
Neurol Res 26:61-6. 2004..Outcome of patients with post-operative hematoma was assessed according to the Glasgow Outcome Scale (GOS) at discharge and at three months. 21 patients (7...
- Implications of excessive fibrinolysis and alpha(2)-plasmin inhibitor deficiency in patients with severe head injuryS Kushimoto
Department of Emergency and Critical Care Medicine, Nippon Medical School, 1 1 5 Sendagi, Bunkyo ku, Tokyo, 113 8603, Japan
Neurosurgery 49:1084-9; discussion 1089-90. 2001..To evaluate the involvement of the fibrinolytic system, especially focused on alpha(2)-plasmin inhibitor, in patients with head injury...
- Fibered electrolytically detachable platinum coils used for the endovascular treatment of intracranial aneurysms. Initial experiences and mid-term results in 474 aneurysmsT Liebig
Klinik für Radiologie und Neuroradiologie, Alfried Krupp von Bohlen und Halbach Krankenhaus, Essen Germany
Interv Neuroradiol 10:5-26. 2004..use and percentage of fibered coils, occlusion rate, procedural complications, early clinical outcome and Glasgow Outcome Scale (GOS) scores...
- Diagnostic MR imaging features of craniocerebral Aspergillosis of sino-nasal origin in immunocompetent patientsA A Siddiqui
Division of Neurosurgery, The Aga Khan University Hospital, Karachi, Pakistan
Acta Neurochir (Wien) 148:155-66; discussion 166. 2006..This retrospective study focuses on characteristic MR imaging features of Aspergillosis (of sinonasal origin) in immunocompetent patients...
- Pneumococcal meningitis in adults: spectrum of complications and prognostic factors in a series of 87 casesStefan Kastenbauer
Department of Neurology, Klinikum Grosshadern, Ludwig Maximilians University, Munich, Germany
Brain 126:1015-25. 2003..The in-hospital mortality was 24.1%. Only 48.3% of the patients had a good outcome at discharge [Glasgow Outcome Scale Score (GOS) = 5]...
- Neuropsychological sequelae of bacterial and viral meningitisH Schmidt
Georg August University Gottingen, Department of Neurology, Gottingen, Germany
Brain 129:333-45. 2006..Patients with a Glasgow Outcome Scale (GOS) of <5 had more frequently impaired test results for non-verbal learning and memory...
- The prognostic value of NSE and S100B from serum and cerebrospinal fluid in patients with spontaneous subarachnoid hemorrhageStefan Moritz
Department of Anesthesiology, University of Regensburg, Medical Center, RegensburgGermany
J Neurosurg Anesthesiol 22:21-31. 2010..At ICU discharge patients' outcome was assessed by the Glasgow outcome scale and occurrence of cerebral infarction, vasospasm and intracranial hypertension were registered...
- Outcome in patients with blunt head trauma and a Glasgow Coma Scale score of 3 at presentationRoukoz B Chamoun
Department of Neurosurgery, Baylor College of Medicine, Houston, Texas 77030, USA
J Neurosurg 111:683-7. 2009..In this paper, the authors' purpose is to report their experience in the management of this patient population, analyzing the mortality rate, prognostic factors, and functional outcome of survivors...
- Treatment of Subarachnoid Hemorrhage with Human AlbuminJose I Suarez; Fiscal Year: 2010..The three-month functional outcome determined',by Glasgow Outcome Scale, Barthel Index, modified Rankin Scale, NIH Stroke Scale and Stroke Impact Scale will be;measured to obtain ..
- Impact of Temperature Profile on Outcome After Traumatic Brain InjuryLori Kennedy Madden; Fiscal Year: 2013..is to examine the association between body temperature and neurologic outcome as measured by Extended Glasgow Outcome Scale (GOS-E) in patients ages 16 years and older after blunt moderate or severe TBI...
- Phase II, randomized controlled trial of brain tissue oxygen monitoringNancy R Temkin; Fiscal Year: 2011..4). Non-futility hypothesis. A relative risk of good outcome measured by the Glasgow Outcome Scale-Extended 6-months after injury of 2.0 is consistent with the results of this phase II study...
- HYPOTHERMIA DURING INTRACRANIAL ANEURYSM SURGERYMichael Todd; Fiscal Year: 2003..limited to the intraoperative period, will result in an improvement in neurologic outcome as measured by Glasgow Outcome Scale at 3months following surgery, and will also result in more rapid improvement during the first ..
- EARLY HEMICRANIECTOMY TO MANAGE TRAUMATIC BRAIN INJURYWilliam Coplin; Fiscal Year: 1999..The primary outcome measure is the six-month Glasgow Outcome Scale. Secondary outcome measures include the Disability Rating Scale, Functional Independence Measures, and the ..
- An Acute Neurobehavioral Program for Improving Functional Status after TBIJanet P Niemeier; Fiscal Year: 2012..will secondarily compare scores on the Disability Rating Scale (DRS), Neurobehavioral Rating Scale (NRS), Glasgow Outcome Scale-Extended (GOSE), Rehabilitation Intensity of Therapy Scale (RITS), and the Frontal Systems Behavior Scale (..
- ANGIOPLASTY IN ANEURYSMAL SUBARACHNOID HEMORRHAGEJ Muizelaar; Fiscal Year: 2005..Primary outcome will be the dichotomized Glasgow Outcome Scale (GOS) at three months...
- DATA MANAGEMENT CENTER--TRIAL OF ORG 10172 IN STROKERobert Woolson; Fiscal Year: 2000..stroke, ORG 10172 is more efficacious than placebo in improving the likelihood of a favorable outcome (Glasgow Outcome Scale of I or II and Barthel Index of 12 or more) at three months after stroke...
- THE EFFECT OF APOE ON OUTCOMES IN TBI ADULTSYvette Conley; Fiscal Year: 2003..a difference in the functional outcomes (mortality, and neuropsychologic evaluation measured using the Glasgow Outcome Scale, Disability Rating Scale and the Neurobehavioral rating scale) at 3 and 6 months after TBI between ..
- HYPERTONIC SALINE FOR INCREASED ICP FOLLOWING HEAD INJU*Lawrence Marshall; Fiscal Year: 2002..the 6-month Glasgow Outcome Scale, the COAT (Children's Orientation Amnesia Test), and the Divided Attention Test.
- Quality of Life in Patients with Brain MetastasesJoseph King; Fiscal Year: 2005..abstract_text> ..
- Clinical trial design and analysis in traumatic brain injuryAndrew Maas; Fiscal Year: 2009..IMPACT: International Mission on Prognosis and Analysis of Clinical Trials in TBI. ..
- CPP Management Information Feedback and NursingCatherine Kirkness; Fiscal Year: 2007..abstract_text> ..
- Gender Differences in Dopamine Function after TBIAmy Wagner; Fiscal Year: 2003....
- Dopamine Genetic Variants Modulating Recovery After TBIAmy Wagner; Fiscal Year: 2008..Through neurolmaging, we hope to better understand how genetics Influences who may benefit from a relevant rehabilitation-based pharmacological treatment strategy. [unreadable] [unreadable] [unreadable]..
- Dopamine Function in TBI--Therapeutic InterventionAmy Wagner; Fiscal Year: 2005..The Departments of Physical Medicine and Rehabilitation, Neurosurgery, Anesthesia/Critical Care Medicine, and Safar Center for Resuscitation Research provide the environment for this study of experimental and clinical brain injury. ..
- Measuring Striatal Neurotransmission in Behaving Rats after Experimental TBIAmy Wagner; Fiscal Year: 2008..The overarching goal is to gain insight into potential mechanisms of action and efficacy of these interventions on cognition and recovery for the clinical population with TBI. [unreadable] [unreadable] [unreadable]..
- Hemodynamics and Outcome in Pediatric Brain InjuryMONICA VAVILALA; Fiscal Year: 2007..The proposed research will be carried out at the University of Washington, well-known known for mentored patient-oriented research. ..
- Cerebral Edema in Pediatric Diabetic KetoacidosisMONICA VAVILALA; Fiscal Year: 2006..unreadable] [unreadable]..
- Glucose Regulation in Acute Stroke Patients (GRASP)Karen Johnston; Fiscal Year: 2007....
- PREDICTIVE RISK MODEL IN ACUTE ISCHEMIC STROKEKaren Johnston; Fiscal Year: 2004..This will be valuable to patients with stroke, providers, payers and developers of new drug therapies. ..
- Post Traumatic Nonconvulsive Epileptiform ActivityPaul Vespa; Fiscal Year: 2005..The hypothesis and unique approach come at a crucial time of failed clinical trials and address an important new therapeutic target. ..
- MRS Detects Metabolic Dysfunction after Brain InjuryPaul Vespa; Fiscal Year: 2009..The knowledge from the proposed studies will have widespread application to critical care of neurotrauma patients. ..
- RADIATION ARTERIOPATHY IN A TRANSGENIC AV FISTULA MODELMichael Lawton; Fiscal Year: 2004..If NO and TGF-01 are involved in the radiation arteriopathy of AVMs, they might be used to enhance the efficacy of conventional stereotactic radiosurgery as part of a gene therapy for high-grade cerebral AVMs. ..
- Genetic factors in outcome from traumatic brain injuryRamon Diaz Arrastia; Fiscal Year: 2008..These studies may provide genetic evidence for a role of specific genes in tissue response after TBI, and may identify novel targets for therapeutic intervention. ..
- Long Term Outcomes in ICU Patients: Delirium & Apolipoprotein ESheila Alexander; Fiscal Year: 2009..This would likely lead to decreased time in the ICU and hospital. ..
- EARLY DETERMINATION OF STROKE SUBTYPE: CT ANGIOGRAPHYScott Kasner; Fiscal Year: 2003..This approach will, for the first time, formally evaluate CTA as a tool for early stroke diagnosis and selection of patients with specific stroke mechanisms for specific mechanism-directed stroke therapies. ..
- Candidate genetic polymorphisms/ HIV-associated dementiaRamon Diaz Arrastia; Fiscal Year: 2002..These studies, is if successful, will provide genetic evidence for a role of specific inflammatory mediators in HAD, and may identify novel targets for therapeutic intervention. ..
- Improving Activity and Participation After Limb Loss: PALS-PlusStephen Wegener; Fiscal Year: 2008..unreadable] [unreadable] [unreadable]..
- Hyperhomocysteinemia in Alzheimer's DiseaseRamon Diaz Arrastia; Fiscal Year: 2003..Each of these specific aims is essential to rationally design a large multicenter trial to determine whether polyvitamin therapy lowers AD risk. ..
- Efficacy of Hypothermia in Pediatric TBIP David Adelson; Fiscal Year: 2004..Parallel clinical specific aims will define the effect of neurotransmitter release in response to treatment with HYPO and the age-related impact of HYPO on early and delayed cell death in children. ..
- Neurorehabilitation with Progesterone & PregnenoloneDavid Wright; Fiscal Year: 2005..Therefore, we will examine two delayed treatment paradigms (7 days & 28 days post injury) on the recovery process at the behavioral and morphological levels of analysis. ..
- ProTECT II: Progesterone for TBI, MCCT Planning GrantDavid Wright; Fiscal Year: 2007..The primary functional outcome will be determined by Glasgow Outcome Scale - Enhanced (GOSE) measured at 6 months after injury...
- Using Biochemical Markers to Detect Abusive Head TraumaRachel Berger; Fiscal Year: 2007..abstract_text> ..
- PATHOPHYSIOLOGY OF CHRONIC CEREBRAL VASOSPASMRobert MacDonald; Fiscal Year: 2005..abstract_text> ..
- TRAUMA-RELATED ERYTHROPOIETIC SUPPRESSIONDavid Livingston; Fiscal Year: 2003..Understanding the mechanisms behind post-trauma anemia will allow therapeutic interventions improving endogenous erythropoiesis to be targeted. ..
- Post Traumatic Brain Injury (TBI) DepressionVani Rao; Fiscal Year: 2008..All three hypotheses will hold true at each time point, even when gender, personal past psychiatric history, family history, and alcohol/substance abuse/depedence are adjusted for in the analysis. [unreadable] [unreadable]..
- Modeling and Assessment of Cerebrovascular AutoregulationMichael Daley; Fiscal Year: 2006..Simulation of ICP with a third order windkessel model of intracranial pressure dynamics will be used to examine the biomechanical mechanisms underlying active and passive regulation of cerebral blood flow. [unreadable] [unreadable]..