Genomes and Genes
substance abuse detection
Summary: Detection of drugs that have been abused, overused, or misused, including legal and illegal drugs. Urine screening is the usual method of detection.
Publications223 found, 100 shown here
- Evaluation of the DRI oxycodone immunoassay for the detection of oxycodone in urineRonald C Backer
Ameritox Limited, Midland, Texas, USA
J Anal Toxicol 29:675-7. 2005..From the presented study, the sensitivity of the DRI-Oxy was 0.991 and the selectivity 0.998. The DRI-Oxy assay provided a highly reliable method for the detection of oxycodone and/or oxymorphone in urine specimens...
- Determination of ketamine and norketamine in hair by gas chromatography/mass spectrometry using two-step derivatizationJin Young Kim
Rapid Commun Mass Spectrom 20:3159-62. 2006
- Barriers to implementing screening and brief interventions in general practice: findings from a qualitative study in NorwayPeter Nygaard
1Norwegian Institute for Alcohol and Drug Research SIRUS, P B 565 Sentrum, 0105 Oslo, Norway
Alcohol Alcohol 46:52-60. 2011....
- A review of the methods, interpretation, and limitations of the urine drug screenE Claire Markway
Department of Pharmacy Services, University of Kentucky, Lexington, Kentucky, USA
Orthopedics 34:877-81. 2011..Either gas chromatography or high-performance liquid chromatography can be used to confirm positive results...
- Assessment of exposure to opiates and cocaine during pregnancy in a Mediterranean city: preliminary results of the "Meconium Project"Simona Pichini
Drug Research and Evaluation Department, Istituto Superiore di Sanita, Rome, Italy
Forensic Sci Int 153:59-65. 2005..Of the four newborns exposed to arecoline, one showed a low birth weight, low intrauterine growth, hyporeflexia and hypotonia...
- Naltrexone for the treatment of amphetamine dependence: a randomized, placebo-controlled trialNitya Jayaram-Lindström
Department of Clinical Neuroscience, Division of Psychiatry, Karolinska Institutet, Stockholm, Sweden
Am J Psychiatry 165:1442-8. 2008..The aim of this study was to investigate the efficacy of naltrexone in comparison with placebo in reducing relapse to amphetamine use in amphetamine-dependent patients...
- How to screen for problematic cannabis use in population surveys: an evaluation of the Cannabis Use Disorders Identification Test (CUDIT) in a Swiss sample of adolescents and young adultsB Annaheim
Swiss Institute for the Prevention of Alcohol and Drug Problems, Lausanne, Switzerland
Eur Addict Res 14:190-7. 2008..The Cannabis Use Disorders Identification Test (CUDIT) is a 10-item questionnaire used for screening cannabis abuse and dependency. The present study evaluated that screening instrument...
- Driving under the influence of drugs -- evaluation of analytical data of drugs in oral fluid, serum and urine, and correlation with impairment symptomsStefan W Toennes
Institute of Forensic Toxicology, Center of Legal Medicine, Kennedyallee 104, D 60596 Frankfurt Main, Germany
Forensic Sci Int 152:149-55. 2005..7%). The data demonstrate that oral fluid is superior to urine in correlating with serum analytical data and impairment symptoms of drivers under the influence of drugs of abuse...
- Oral fluid testing for drugs of abuseWendy M Bosker
Maastricht University, Neuropsychology and Psychopharmacology, Experimental Psychopharmacology Unit, Maastricht, The Netherlands
Clin Chem 55:1910-31. 2009..Although OF testing is now commonplace in many monitoring programs, the greatest current limitation is the scarcity of controlled drug administration studies available to guide interpretation...
- Detection times of drugs of abuse in blood, urine, and oral fluidAlain G Verstraete
Clinical Biology Laboratory, Ghent University Hospital, B 9000 Ghent, Belgium
Ther Drug Monit 26:200-5. 2004..The duration of detection of GHB is much shorter. After a single dose of 1 or 2 ng of flunitrazepam, the most sensitive methods can detect 7-aminoflunitrazepam for up to 4 weeks in urine...
- Drug use in English professional footballI Waddington
University College Chester, UK
Br J Sports Med 39:e18; discussion e18. 2005....
- Developing limits for driving under cannabisFranjo Grotenhermen
Nova Institut, Hürth, Germany
Addiction 102:1910-7. 2007..Development of a rational and enforceable basis for controlling the impact of cannabis use on traffic safety...
- Development of a self-report screening instrument for assessing potential opioid medication misuse in chronic pain patientsLaura L Adams
The Eugene McDermott Center for Pain, The University of Texas Southwestern Medical Center at Dallas, 75390, USA
J Pain Symptom Manage 27:440-59. 2004..Future psychometric analyses will consider predictive validity and examine shortened versions of the instrument...
- Oral fluid testing for driving under the influence of drugs: history, recent progress and remaining challengesAlain G Verstraete
Laboratory of Clinical Biology, Ghent University Hospital and Faculty of Medicine and Health Sciences, Ghent University, De Pintelaan 185, B 9000 Ghent, Belgium
Forensic Sci Int 150:143-50. 2005....
- Cannabis use and the GP: brief motivational intervention increases clinical enquiry by GPs in a pilot studyJim McCambridge
National Addiction Centre, Maudsley Institute of Psychiatry, Addiction Sciences Building, 4 Windsor Walk, Denmark Hill, London SE5 8AF
Br J Gen Pract 53:637-9. 2003..Substantially more positive attitudes and greater clinical activity were observed following receipt of intervention...
- The relationship between performance on the standardised field sobriety tests, driving performance and the level of Delta9-tetrahydrocannabinol (THC) in bloodK Papafotiou
Swinburne Centre for Neuropsychology, Swinburne University of Technology, PO Box 218, Hawthorn, Vic 3122, Australia
Forensic Sci Int 155:172-8. 2005....
- Prevalence of illicit drug use among the Italian athlete population with special attention on drugs of abuse: a 10-year reviewSabina Strano Rossi
Laboratorio Antidoping, Federazione Medico Sportiva Italiana, Rome, Italy
J Sports Sci 29:471-6. 2011..However, due to the particular population studied, it must be considered an underestimation of the phenomenon among elite athletes with respect to the general population...
- Toward a more parsimonious approach to drug recognition expert evaluationsAmy J Porath-Waller
Canadian Centre on Substance Abuse, Ottawa, Ontario K1P 5E7, Canada
Traffic Inj Prev 10:513-8. 2009..The purpose of this study is to statistically identify the set of drug-related cues from Drug Evaluation and Classification (DEC) evaluations that significantly predict the substance used by suspected drug-impaired drivers...
- Analytical toxicologyHans H Maurer
Department of Experimental and Clinical Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Saarland University, Homburg, Germany
EXS 100:317-37. 2010..The importance of quality control and possibilities and limitations of interpretation of the analytical result are also discussed...
- Evaluation of on-site oral fluid screening using Drugwipe-5(+), RapidSTAT and Drug Test 5000 for the detection of drugs of abuse in driversSarah M R Wille
Federal Public Service Justice, National Institute of Criminalistics and Criminology, Vilvoordsesteenweg 100, Brussels, Belgium
Forensic Sci Int 198:2-6. 2010..They believe that their ease of use and diminished amount of false positive results in comparison with urine screening will lead to more roadside tests and more appropriate juridical measures...
- Using molecular similarity to highlight the challenges of routine immunoassay-based drug of abuse/toxicology screening in emergency medicineMatthew D Krasowski
Department of Pathology, University of Pittsburgh, Pittsburgh, PA, USA
BMC Emerg Med 9:5. 2009..For immunoassays targeted at a particular class of drugs, there can also be false negatives if there is failure to detect some drugs or their metabolites within that class...
- Impact of a reduction in heroin availability on patterns of drug use, risk behaviour and incidence of hepatitis C virus infection in injecting drug users in New South Wales, AustraliaLisa Maher
National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, St Vincent s Medical Centre, 376 Victoria Street, Darlinghurst, Sydney, NSW 10, Australia
Drug Alcohol Depend 89:244-50. 2007....
- Development of a metabolomic approach based on liquid chromatography-high resolution mass spectrometry to screen for clenbuterol abuse in calvesFrédérique Courant
Laboratoire d Etude des Résidus et Contaminants dans les Aliments LABERCA, Ecole Nationale Vétérinaire de Nantes ENVN, USC INRA 2013, BP 50707, F 44307 Nantes Cedex 3, France
Analyst 134:1637-46. 2009..This new approach may be considered of valuable interest to overcome current limitations in the control of growth promoters' abuse, with promising perspectives in terms of screening...
- Validation of an ELISA-based screening assay for the detection of amphetamine, MDMA and MDA in blood and oral fluidMarleen Laloup
Federal Public Service Justice, National Institute of Criminalistics and Criminology NICC, Section Toxicology, Vilvoordsesteenweg 98, 1120 Brussels, Belgium
Forensic Sci Int 153:29-37. 2005..It should be emphasized that method validation should be performed for each type of biological matrix...
- Testing for substance use in trauma patients: are we doing enough?Jason A London
Division of Trauma and Emergency Surgery, Department of Surgery, University of California, Davis Medical Center, Sacramento, CA 95817, USA
Arch Surg 142:633-8. 2007..Only a fraction of trauma patients are being tested for substance use, and the proportion of those tested may have decreased over time...
- The 3-metros study of drugs and crime in South Africa: findings and policy implicationsCharles D Parry
Alcohol and Drug Abuse Research Group, Medical Research Council, P O Box 19070, Tygerberg Cape Town, 7505, South Africa
Am J Drug Alcohol Abuse 30:167-85. 2004....
- Testing for fetal exposure to illicit drugs using umbilical cord tissue vs meconiumD Montgomery
Department of Women and Newborns, Intermountain Health Care and McKay Dee Hospital, Ogden, UT 84403, and Department of Family and Preventive Medicine, University of Utah, Salt Lake City, UT, USA
J Perinatol 26:11-4. 2006..We assessed the agreement of testing for fetal exposure to illicit drugs contrasting paired specimens of meconium vs umbilical cord tissue...
- Evaluation of indirect biomarkers for detecting corticosteroids used as illegal growth promoters in beef cattleM Vascellari
Department of Histopathology, Istituto Zooprofilattico Sperimentale delle Venzie, Via dell Università 10, 35020 Legnaro, Padova, Italy
Vet Rec 163:147-51. 2008..The samples that were positive by chemical analysis had cortisol concentrations of less than 2.0 ng/ml, whereas the mean cortisol concentration of the negative samples was 10.3 ng/ml...
- Drug screening of preserved oral fluid by liquid chromatography-tandem mass spectrometryElisabeth Leere Øiestad
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, Oslo, Norway
Clin Chem 53:300-9. 2007..Development of methods for extensive drug screening in oral fluid is warranted...
- Biological markers of drug use in the club settingBrenda A Miller
Prevention Research Center, Pacific Institute for Research and Evaluation PIRE, 1995 University Avenue, Suite 450, Berkeley, California 94704, USA
J Stud Alcohol Drugs 70:261-8. 2009..The prevalence of drug and alcohol use among patrons of clubs featuring electronic music dance events was determined by using biological assays at entrance and exit...
- Identification of prenatal amphetamines exposure by maternal interview and meconium toxicology in the Infant Development, Environment and Lifestyle (IDEAL) studyTeresa R Gray
Chemistry and Drug Metabolism, National Institute on Drug Abuse, National Institutes of Health, Baltimore, MD, USA
Ther Drug Monit 31:769-75. 2009..Low confirmation rates in meconium reinforce the need for confirmatory testing following positive screening results and additional research to identify alternative biomarkers...
- Toxicology screening results: injury associations among hospitalized trauma patientsRichard D Blondell
Department of Family Medicine, State University of New York, University at Buffalo, 14215 3021, USA
J Trauma 58:561-70. 2005..Substance abuse is associated with injuries, but these associations have not been well characterized by type of substance and injury type...
- A search for guidance: examining prenatal substance exposure protocolsGail L Zellman
RAND, Santa Monica, California 90407 2138, USA
Matern Child Health J 6:205-12. 2002..To describe key elements of a set of hospital prenatal substance exposure protocols, and to relate variations in protocol content to the state legislative environment and hospital characteristics...
- Neonatal illicit drug screening practices in Iowa: the impact of utilization of a structured screening protocolR Oral
Department of Pediatrics, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
J Perinatol 26:660-6. 2006..The purpose of the study was to determine the neonatal illicit drug screening practices of Iowa birthing hospitals...
- Using umbilical cord tissue to detect fetal exposure to illicit drugs: a multicentered study in Utah and New JerseyD P Montgomery
Department of Women and Newborns, Intermountain Healthcare, Salt Lake City, UT 84403, USA
J Perinatol 28:750-3. 2008..We assessed umbilical cord tissue as a means of detecting fetal exposure to five classes of drugs of abuse...
- Unsuspected exposure to cocaine in preschool children from a Mediterranean city detected by hair analysisXavier Joya
Unitat de Recerca Infancia i Entorn, Institut Municipal d Investigació Mèdica Hospital del Mar, Barcelona, Spain
Ther Drug Monit 31:391-5. 2009..In the light of these results, we advocate general hair screening to disclose exposure to cocaine and other drugs of abuse in children from risky environments, which could provide the basis for specific social and health interventions...
- Substance abuse treatment linked with prenatal visits improves perinatal outcomes: a new standardN C Goler
Department of Obstetrics and Gynecology, The Permanente Medical Group, Northern California Region, Vallejo, CA 94590 2406, USA
J Perinatol 28:597-603. 2008..To evaluate the impact of Early Start, an obstetric clinic-based prenatal substance abuse treatment program, on perinatal outcomes...
- Multi-residue screening of a minimum package of anabolic steroids in urine with GC-MSP R Kootstra
RIVM, National Institute of Public Health and the Environment, Laboratory for Food and Residue Analyses, European Union Community Reference Laboratory, P O Box 1, 3720 BA Bilthoven, The Netherlands
Anal Chim Acta 586:82-92. 2007..Results of validation experiments are presented. The method is flexible and due to the non-specific sample clean-up more and new anabolic compounds can be easily added in order to new monitoring requirements...
- Amphetamine excretion profile following multidose administration of mixed salt amphetamine preparationJohn T Cody
Academy of Health Sciences, MCCS HMP PA Branch, Fort Sam Houston, Texas 78234 6138, USA
J Anal Toxicol 28:563-74. 2004..Coupling this data with drug concentration makes it possible for forensic toxicologists and MROs to come to an informed decision regarding the involvement of this drug in a positive drug test result...
- Fast gas chromatographic/mass spectrometric determination of diuretics and masking agents in human urine: Development and validation of a productive screening protocol for antidoping analysisV Morra
Consorzio Piemontese per la Prevenzione e Repressione del Doping e di altri Usi Illeciti dei Farmaci, Regione Gonzole 10, 10043 Orbassano, Turin, Italy
J Chromatogr A 1135:219-29. 2006..Fast quadrupole MS electronics allows high scan rates and effective data acquisition both in scan and selected ion monitoring modes...
- Metabolism and excretion of anabolic steroids in doping control--new steroids and new insightsPeter Van Eenoo
Doping control laboratory DoCoLab, Ghent University Ugent, Technologiepark 30, B 9052 Zwijnaarde, Belgium
J Steroid Biochem Mol Biol 101:161-78. 2006..Additionally an update and insight on new aspects for "older" steroids with respect to doping control is given...
- Urine benzodiazepine screening using Roche Online KIMS immunoassay with beta-glucuronidase hydrolysis and confirmation by gas chromatography- mass spectrometryKevin L Klette
Navy Drug Screening Laboratory, 320 B Street, Great Lakes, Illinois 60088 2815, USA
J Anal Toxicol 29:193-200. 2005..The Online BZD IA modified by the automatic addition of beta-glucuronidase appears well adapted for the rapid detection of BZDs and their metabolites in human urine...
- Erythropoietin and blood dopingN Robinson
Swiss Laboratory for Doping Analyses, Institute of Legal Medicine, Lausanne, Switzerland
Br J Sports Med 40:i30-4. 2006..To outline the direct and indirect approaches in the fight against blood doping in sports, the different strategies that have been used and are currently being used to fight efficiently against blood doping are presented and discussed...
- Use of isotope ratio mass spectrometry to detect doping with oral testosterone undecanoate: inter-individual variability of 13C/12C ratioNorbert Baume
Laboratoire Suisse d Analyse du Dopage, Institut Universitaire de Medecine Legale, Lausanne, Switzerland
Steroids 71:364-70. 2006..According to T/E ratios and delta(13)C-values, the washout period after 80 mg TU intake was less than 48 h for all subjects and no accumulation phenomenon was observed upon chronic oral administration...
- Injectable, sustained-release naltrexone for the treatment of opioid dependence: a randomized, placebo-controlled trialSandra D Comer
Division on Substance Abuse, New York State Psychiatric Institute, and Department of Psychiatry, College of Physicians and Surgeons of Columbia University, New York 10032, USA
Arch Gen Psychiatry 63:210-8. 2006..Oral naltrexone can completely antagonize the effects produced by opioid agonists. However, poor compliance with naltrexone has been a major obstacle to the effective treatment of opioid dependence...
- Validation and application of a screening method for beta2-agonists, anti-estrogenic substances and mesocarb in human urine using liquid chromatography/tandem mass spectrometryMin Jung Kang
Bioanalysis and Biotransformation Center, Korea Institute of Science and Technology, 130 650, Hawolgokdong 39 1, Seoul, Korea
Rapid Commun Mass Spectrom 21:252-64. 2007..8%. The limit of detection was below 10 ng/mL except formestane (300 ng/mL) and aminoglutethimide (100 ng/mL). The validated method was applied for the analysis of excretion samples...
- Detection and quantification of glucuro- and sulfoconjugated metabolites in human urine following oral administration of xenobiotic 19-norsteroidsY L Tseng
Institute of Pharmacology and Toxicology, Tzu Chi University, 701 Chung Yan Road, Sec 3, Hualien 970, Taiwan
Steroids 71:817-27. 2006..Results from the excretion studies demonstrate significance of sulfate-conjugated metabolites on interpretation of misuse of the 19-norsteroids...
- Distribution of methylenedioxymethamphetamine (MDMA) and methylenedioxyamphetamine (MDA) in postmortem and antemortem specimensRay H Liu
Department of Forensic Toxicology, Institute of Forensic Medicine, Ministry of Justice, Taipei, Taiwan
J Anal Toxicol 30:545-50. 2006..This observation is consistent with the relative drug/metabolite incorporation rates reported for cocaine/benzoylecgonine, tetrahydrocannabinol/tetrahydrocannabinoic acid, and MDMA/MDA...
- False positive phencyclidine results caused by venlafaxinePatricio Molero Santos
Am J Psychiatry 164:349. 2007
- Urine drug screening: practical guide for cliniciansKaren E Moeller
University of Kansas Medical Center, Kansas City, KS 66160 7231, USA
Mayo Clin Proc 83:66-76. 2008..Other pitfalls, such as adulteration, substitution, and dilution of urine samples, are discussed. Pragmatic concepts summarized in this article should minimize the potential risks of misinterpreting urine drug screens...
- Cocaine and metabolites urinary excretion after controlled smoked administrationMarilyn A Huestis
Chemistry and Drug Metabolism, Intramural Research Program, National Institute on Drug Abuse, National Institutes of Health, Baltimore, Maryland 21224, USA
J Anal Toxicol 31:462-8. 2007..T(max) was not dose-dependent. All metabolites were detected in some subjects within 2 h. EC concentrations were significantly higher after smoked cocaine in a precise delivery coil compared to a glass "crack" pipe...
- Introduction of HPLC/orbitrap mass spectrometry as screening method for doping controlE D Virus
Moscow Antidoping Center, Elizavetynsky10, 105005, Moscow, Russia
J Mass Spectrom 43:949-57. 2008..The relative standard deviation (RSD) of the intraday precision (n = 6) ranged from RSD = 16-22%, whereas the interday precision (n = 18), ranged from RSD = 17-26%, depending on the solute concentration investigated...
- Elimination of 7-aminoclonazepam in urine after a single dose of clonazepamAdam Negrusz
Department of Biopharmaceutical Sciences M C 865, College of Pharmacy, University of Illinois at Chicago, 833 South Wood Street, Chicago, IL 60612, USA
Anal Bioanal Chem 376:1198-204. 2003..The range of concentrations detected was from 73.0 pg x mL(-1) to 183.2 ng x mL(-1). CLO was not detected in any of the samples...
- Sports drug testing--an analyst's perspectiveGraham J Trout
Australian Sports Drug Testing Laboratory, Australian Government Analytical Laboratories, Sydney, Australia
Chem Soc Rev 33:1-13. 2004..The contest between those who wish to cheat and those who wish to maintain fair play in sport is an ongoing one...
- National academy of clinical biochemistry laboratory medicine practice guidelines: recommendations for the use of laboratory tests to support poisoned patients who present to the emergency departmentAlan H B Wu
Department of Pathology and Laboratory Medicine, Hartford Hospital, Hartford, CT 06102, USA
Clin Chem 49:357-79. 2003..Exposure to drugs and toxins is a major cause for patients' visits to the emergency department (ED)...
- Screening for 18 diuretics and probenecid in doping analysis by liquid chromatography-tandem mass spectrometryK Deventer
Ghent University, Doping Control Unit, Faculty of Veterinary Medicine, Salisburylaan 133, B 9820 Merelbeke, Belgium
Biomed Chromatogr 16:529-35. 2002..All diuretics could be detected for periods up to 96 h after the intake of therapeutic amounts...
- Doping: a paradigm shift has taken place in testingPierre Edouard Sottas
Nature 455:166. 2008
- Carbon isotope ratio (delta13C) values of urinary steroids for doping control in sportAdam T Cawley
Australian Sports Drug Testing Laboratory ASDTL, National Measurement Institute NMI, 1 Suakin Street, Pymble, NSW 2073, Australia
Steroids 74:379-92. 2009....
- Quinolones and false-positive urine screening for opiates by immunoassay technologyL R Baden
Division of Infectious Diseases, Brigham and Women s Hospital, 15 Francis St, PBB A400, Boston, MA 02115, USA
JAMA 286:3115-9. 2001..Millions of assays are performed each year to monitor for substance abuse in various settings. When common medications cross-react with frequently used testing assays, false-positive results can lead to invalid conclusions...
- Urine drug screening in the medical settingCatherine A Hammett-Stabler
Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC, USA
Clin Chim Acta 315:125-35. 2002..The reasons for these include the drugs involved, the sample, the methods utilized to perform the tests, and the level of understanding of the physician using the data, all of which are closely related to the other...
- Analysis of exogenous dehydroepiandrosterone excretion in urine by gas chromatography/combustion/isotope ratio mass spectrometryM Ueki
Doping Control Laboratory, Mitsubishi Kagaku Bio Clinical Laboratories, Inc, 3 30 1 Shimura, Itabashi ku, Tokyo 174 8555, Japan
Rapid Commun Mass Spectrom 13:2237-43. 1999..Thus, the deviations in delta-values of DHEA and its diol metabolites are considered to be conclusive evidence for detecting doping with DHEA. Some successful cases of detection of doping with DHEA from athletes are also reported...
- Evaluation of testosterone/epitestosterone ratio influential factors as determined in doping analysisD H van de Kerkhof
Utrecht Institute of Pharmaceutical Sciences, Department of Human Toxicology, University of Utrecht, The Netherlands
J Anal Toxicol 24:102-15. 2000....
- A marijuana screening inventory (experimental version): description and preliminary psychometric propertiesDale Alexander
Graduate School of Social Work, University of Houston, Houston, Texas 77204 4013, USA
Am J Drug Alcohol Abuse 29:619-46. 2003..This article describes the Marijuana Screening Inventory (MSI-X) and its preliminary psychometric reliability, factor analyses, and factor structure...
- Identification and measurement of illicit drugs and their metabolites in urban wastewater by liquid chromatography-tandem mass spectrometrySara Castiglioni
Department of Environmental Health Sciences, Mario Negri Institute for Pharmacological Research, Via Eritrea 62, 20157 Milan, Italy
Anal Chem 78:8421-9. 2006..As previously reported for cocaine, this method could be useful to estimate and monitor drug consumption in the population in real time, helping social scientists and authorities to combat drug abuse...
- Analytical techniques for drug detection in oral fluidPirjo Lillsunde
National Public Health Institute, Drug Research Unit, Helsinki, Finland
Ther Drug Monit 30:181-7. 2008..Several sensitive methods for drug testing in OF have been developed during the last years...
- The reliability and validity of the Severity of Dependence Scale for detecting cannabis dependence in psychosisL Hides
School of Applied Psychology, Griffith University, Australia
Addiction 102:35-40. 2007..To determine the reliability and validity of the Severity of Dependence Scale (SDS) for detecting cannabis dependence in a large sample of in-patients with a schizophrenia spectrum disorder...
- Prevalence of cocaine and marijuana use in the last trimester of adolescent pregnancy: socio-demographic, psychosocial and behavioral characteristicsSandro Sendin Mitsuhiro
Alcohol and Drug Research Unit UNIAD, Psychiatry Department, Federal University of Sao Paulo, Rua Botucatu, 394, 04023 061, Brazil
Addict Behav 32:392-7. 2007....
- A high-throughput multicomponent screening method for diuretics, masking agents, central nervous system (CNS) stimulants and opiates in human urine by UPLC-MS/MSJohn Olof Thorngren
Doping Control Laboratory, Karolinska University Hospital, Huddinge, Sweden
J Mass Spectrom 43:980-92. 2008..The report can also be processed automatically using an application software, which interpret the data and indicate if there is a suspicious sample. One 96-well plate can be analyzed within 16 h...
- Mass spectrometry in sports drug testing: Structure characterization and analytical assaysMario Thevis
Institute of Biochemistry and Center for Preventive Doping Research, German Sport University Cologne, Carl Diem Weg 6, 50933 Cologne, Germany
Mass Spectrom Rev 26:79-107. 2007....
- Isotopic pattern and accurate mass determination in urine drug screening by liquid chromatography/time-of-flight mass spectrometrySuvi Ojanperä
Department of Forensic Medicine, University of Helsinki, Helsinki, Finland
Rapid Commun Mass Spectrom 20:1161-7. 2006..The results show that isotopic pattern matching by SigmaFit is a powerful means of identification in addition to accurate mass measurement...
- Performance characteristics of a carbon isotope ratio method for detecting doping with testosterone based on urine diols: controls and athletes with elevated testosterone/epitestosterone ratiosR Aguilera
UCLA Olympic Analytical Laboratory, Department of Molecular and Medical Pharmacology, University of California at Los Angeles, Los Angeles, CA 90025, USA
Clin Chem 47:292-300. 2001..Carbon isotope ratio methods are used in doping control to determine whether urinary steroids are endogenous or pharmaceutical...
- Behavioral monitoring and urine toxicology testing in patients receiving long-term opioid therapyNathaniel P Katz
Pain Trials Center, Brigham and Women s Hospital, Boston, Massachusetts, USA
Anesth Analg 97:1097-102, table of contents. 2003..Requiring a report of behavioral issues and urine toxicology screens for patients receiving chronic opioids creates a more comprehensive monitoring system than either alone...
- From population- to subject-based limits of T/E ratio to detect testosterone abuse in elite sportsPierre Edouard Sottas
Swiss Laboratory for Doping Analyses, Institut de Medecine Legale, Universite de Lausanne, Chemin des Croisettes 22, 1066 Epalinges, Switzerland
Forensic Sci Int 174:166-72. 2008..We found that this screening test heightens drastically the capacity to detect testosterone abuse, at no additional financial and administrative expenses for anti-doping authorities...
- A general screening method for doping agents in human urine by solid phase extraction and liquid chromatography/time-of-flight mass spectrometryMarjo Kolmonen
Forensic Toxicology Division, Department of Forensic Medicine, University of Helsinki, Finland
Anal Chim Acta 585:94-102. 2007..The suitability of the LC/TOFMS method for doping control was demonstrated with authentic urine samples...
- Multi-detection of corticosteroids in sports doping and veterinary control using high-resolution liquid chromatography/time-of-flight mass spectrometryM E Touber
RIKILT Institute of Food Safety, P O Box 230, Wageningen, 6700 AE, The Netherlands
Anal Chim Acta 586:137-46. 2007..4 microg L(-1), respectively. The method can be easily extended with other banned substances of interest, as demonstrated by the addition of 21 beta2-agonists to the original analyte mixture in urine, without causing any interferences...
- Cocaine detection in maternal and neonatal hair: implications to fetal toxicologyFacundo Garcia-Bournissen
Motherisk Program, Division of Clinical Pharmacology and Toxicology, Hospital for Sick Children, University of Toronto, Toronto, Canada
Ther Drug Monit 29:71-6. 2007..More research is needed to understand the mechanisms leading to placental defense against cocaine...
- Effects of a community-based drug use prevention program targeting licensed premisesJohanna Gripenberg
Department of Public Health Sciences, Karolinska Institute, Stockholm, Sweden
Subst Use Misuse 42:1883-98. 2007..Further research is necessary to explore the effectiveness of community-based drug use prevention programs targeting licensed premises...
- Broad-spectrum toxicological analysis of hair based on capillary zone electrophoresis-time-of-flight mass spectrometryRossella Gottardo
Department of Medicine and Public Health, Unit of Forensic Medicine, University of Verona, Verona, Italy
J Chromatogr A 1159:190-7. 2007..A single liquid-liquid extraction procedure was applied for all analytes, allowing the detection of a broad spectrum of basic drugs and their major metabolites...
- Prevalence of psychoactive substances in truck drivers in the Nord-Pas-de-Calais region (France)Laurence Labat
Laboratoire Toxicologie et Génopathies, CHRU de Lille, Av Professeur J Leclercq, 59037 Lille Cedex, France
Forensic Sci Int 174:90-4. 2008..In conclusion, the authors think that it will be of a great interest to test urine of truck drivers for other classes of psychoactive drugs, using a liquid chromatography-mass spectrometry method...
- Driving under the influence in Greece: a 7-year survey (1998-2004)Stavroula A Papadodima
Department of Forensic Medicine and Toxicology, School of Medicine, University of Athens, M Asias 75, Goudi, Athens 115 27, Greece
Forensic Sci Int 174:157-60. 2008..The above values were compared with those of a previous study concerning the period 1995-1997 and the reasons for the reduction of the number of alcohol-related traffic accidents during the last years are discussed...
- Patterns in drug use in the United Kingdom as revealed through analysis of hair in a large population sampleLolita Tsanaclis
TrichoTech, No 1 Pentwyn Business Centre, Cardiff, United Kingdom
Forensic Sci Int 170:121-8. 2007..This means that the chances of identifying people on drugs in the workplace by testing hair samples are twice as likely than urine samples...
- Validation of a procedure for the gas chromatography-mass spectrometry analysis of cocaine and metabolites in pericardial fluidMaria Teresa Contreras
Pharmacology Research Unit, Institut Municipal d Investigacio Medica IMIM, Barcelona, Spain
J Anal Toxicol 31:75-80. 2007..In this study, the procedure has been successfully applied to a number of forensic cases involving cocaine intoxication...
- Rapid quantification of buprenorphine-glucuronide and norbuprenorphine-glucuronide in human urine by LC-MS-MSS Hegstad
Norwegian Institute of Public Health, Division of Forensic Toxicology and Drug Abuse, P O Box 4404 Nydalen, NO 0403 Oslo, Norway
J Anal Toxicol 31:214-9. 2007..The LC-MS-MS method proved to be robust and specific for the determination of BUP-G and NBUP-G in urine...
- Recent paramethoxymethamphetamine (PMMA) deaths in TaiwanDong Liang Lin
Institute of Forensic Medicine, Ministry of Justice, Taipei, Taiwan
J Anal Toxicol 31:109-13. 2007..The corresponding data for PMMA were 4.312, 4.806, and 1.208-15.824 microg/mL, respectively. Other drugs, such as MDA, MDMA, ketamine, norketamine, hydroxymidazolam, methamphetamine, and pentobarbital, were also found in these cases...
- Evaluation of the IDS One-Step ELISA kits for the detection of illicit drugs in hairMarie Laure Pujol
Laboratoire ChemTox, Illkirch, France
Forensic Sci Int 170:189-92. 2007..This technology should find interest in workplace drug testing or driving license regranting, especially when many samples have to be tested with a high rate of negative samples, as ELISA is an easy and high-throughput method...
- Distribution of drugs of abuse within specific regions of the human brainT Stimpfl
Department of Forensic Medicine, Medical University of Vienna, Vienna, Austria
Forensic Sci Int 170:179-82. 2007....
- Simultaneous quantification of opiates, amphetamines, cocaine and metabolites and diazepam and metabolite in a single hair sample using GC-MSRosa Cordero
Toxicology Unit, Imperial College London, St Dunstan s Road, London W6 8RP, United Kingdom
J Chromatogr B Analyt Technol Biomed Life Sci 850:423-31. 2007..The results of the analysis of hair taken from four patients attending a drug treatment clinic and six hair samples including head hair, pubic hair, axial hair and beard taken at post-mortem are presented...
- Differentiation between drug use and environmental contamination when testing for drugs in hairLolita Tsanaclis
TrichoTech, No 1 Pentwyn Business Centre, Cardiff CF23 7HB, United Kingdom
Forensic Sci Int 176:19-22. 2008....
- Hair analysis of anabolic steroids in connection with doping control-results from horse samplesP Anielski
Institute of Doping Analysis and Sports Biochemistry, Dresdner Strasse 12, D 01731 Kreischa, Germany
J Mass Spectrom 43:1001-8. 2008..Trimethylsilyl (TMS) and tert-butyl dimethylsilyl derivatives were detected by gas chromatography-high-resolution mass spectrometry (GC-HRMS) and gas chromatography-tandem mass spectrometry (GC-MS/MS)...
- Hair analysis for illicit drugs by using capillary zone electrophoresis-electrospray ionization-ion trap mass spectrometryRossella Gottardo
Department of Medicine and Public Health, Unit of Forensic Medicine, University of Verona, Verona, Italy
J Chromatogr A 1159:185-9. 2007..47% for areas in real samples, in both intra-day and day-to-day experiments. On these grounds, the described method can be proposed for rapid, selective and accurate toxicological hair analysis for both clinical and forensic purposes...
- Results of hair analyses for drugs of abuse and comparison with self-reports and urine testsF Musshoff
Institute of Legal Medicine, Rheinische Friedrich Wilhelms University, Stiftsplatz 12, 53111 Bonn, Germany
Forensic Sci Int 156:118-23. 2006....
- Validation of an ELISA method for screening methadone in postmortem bloodMatthew Juhascik
UMass Memorial Forensic Toxicology Laboratory, Worcester, Massachusetts 01605, USA
J Anal Toxicol 30:617-20. 2006..The Venture Labs methadone assay demonstrated a sensitivity of 96.7%+/-2.3% and a specificity of 98.3%+/-1.7% relative to the GC-MS method...
- [Drug addiction in the medico-legal certification of the Department of Forensic Medicine of Medical University of Gdańsk in the years 1996-2005]Katarzyna Galer-Tatarowicz
Z Katedry i Zakfadu Medycyny Sedowej Akademii Medycznej w Gdarisku Kierownik dr hab med Z Jankowski
Arch Med Sadowej Kryminol 57:277-84. 2007..The presence of both ethanol and drugs was detected and confirmed mainly in post-mortem biological materials...
- Roadside oral fluid testing: comparison of the results of drugwipe 5 and drugwipe benzodiazepines on-site tests with laboratory confirmation results of oral fluid and whole bloodAnna Pehrsson
National Public Health Institute, Drug Research Unit, Mannerheimintie 166, FI 00300 Helsinki, Finland
Forensic Sci Int 175:140-8. 2008....
- Biological, clinical, and forensic analysis using comprehensive two-dimensional gas chromatographyNicholas H Snow
Department of Chemistry and Biochemistry, Seton Hall University, South Orange, New Jersey, USA
Adv Chromatogr 45:215-43. 2007
- Detection of cocaine analytes and opiates in nails from postmortem casesDavid A Engelhart
Office of the Cuyahoga County Coroner, Cleveland, Ohio 44106, USA
J Anal Toxicol 26:489-92. 2002..These results demonstrate the usefulness of nails as postmortem specimens in detecting drugs of abuse...
- Value of hair analysis in postmortem toxicologyPascal Kintz
Institut de Medecine Legale, 11, rue Humann, F 67000 Strasbourg, France
Forensic Sci Int 142:127-34. 2004..Moreover, the window of drug detection is dramatically extended to weeks, months or even years. The aim of this review is to document the current status of hair analysis in postmortem toxicology...
- On-site testing of illicit drugs: the use of the drug-testing device "Toxiquick"T Biermann
Department of Forensic Medicine, University Erlangen Nuremberg, Universitaetsstrasse 22, D 91054 Erlangen, Germany
Forensic Sci Int 143:21-5. 2004..Except for cannabinoids, the number of false negative results was relatively small, whereas false positive results ranged between 32.2% for opiates and 10.7% for benzoylecgonine...
- Evaluation of the One-Step ELISA kit for the detection of buprenorphine in urine, blood, and hair specimensV Cirimele
Laboratoire de Toxicologie, Institut de Medecine Legale, 11 rue Humann, F 67085 Strasbourg, France
Forensic Sci Int 143:153-6. 2004..3-15.6 ng/mL), did not cause a false negative response by the immunoassay...
- Development of a screening method for the most commonly abused anticholinergic drugs in Jordan; trihexyphenidyl, procyclidine and biperidenKamal A Hadidi
Forensic Medicine and Toxicology Division, Faculty of Medicine, University of Jordan, Amman 11942, Jordan
Leg Med (Tokyo) 6:233-41. 2004..The method will offer the clinicians and the legal authority the right diagnosis regarding the anticholinergic involved in any case of abuse with less than 1 h per sample (plasma or urine) from the time of receiving...
- PARAMETRIC STUDIES OF DRUG ABUSE ABSTINENCE INCENTIVESMaxine Stitzer; Fiscal Year: 2004..The information to be obtained will further advance our understanding of incentive therapies and how these can be tailored for improved efficacy in specific populations. ..
- Experimental Analysis of Smoking RelapseMaxine Stitzer; Fiscal Year: 2006..Further, valuable information will be obtained about the potentially powerful effects of smoking after brief periods of abstinence (lapse) using these new models. ..
- Methadone maintenance and HIV risk in UkraineGeorge Woody; Fiscal Year: 2007..unreadable] [unreadable]..
- Prescription Psychotherapeutic Drug Use Among Older AdultsYu Ping Chang; Fiscal Year: 2011..Clinicians need to routinely screen medication-taking behaviors among older adults who are prescribed psychotherapeutic drug in order to practice prevention and early intervention. ..
- Computerized alcohol screening for children and adolescents (cASCA) in primary caJohn R Knight; Fiscal Year: 2013..g., those with/without friends who drink); and explore the possible effects of the cASCA system on drinking at 3-, 6-, 9-, and 12-month follow-ups. ..
- Enhanced brief Intervention for linking opiate abusing EMS patients to treatmentAmy Knowlton; Fiscal Year: 2013..The academic-interagency collaboration builds on study team members'decades of successful relevant research with the study population. . ..
- Interactive Simulation to Train Prescription Drug Abuse ScreeningDale Olsen; Fiscal Year: 2009..Screening patients for prescription drug abuse in primary care settings may help identify abuse sooner and lead to life-changing interventions which could reduce the negative impact of prescription and other drug abuse and addiction. ..
- PARTNER VIOLENCE DURING TRANSITIONS IN PREGNANCYSandra Martin; Fiscal Year: 2001..These newly developed procedures are appropriate for the analysis of longitudinal data (both continuous and categorical outcomes) and will allow for the inclusion of potentially important time-dependent covariates in the study models. ..
- IDENTIFYING SUBSTANCE ABUSE DISORDERS IN MENTALLY ILLStanley Rosenberg; Fiscal Year: 1999....
- WEB-BASED DRUG-FREE WORKPLACE DEVELOPMENTJ Walsh; Fiscal Year: 2004..Furthermore, we intend to develop a mechanism to evaluate the use of the website and utilize the information to demonstrate the feasibility and commercial viability of the concept. ..
- Six Programs for the Future of Alcohol SafetyRobert Voas; Fiscal Year: 2007..Voas to become involved in a broader range of programs than if he otherwise were limited by taking on the full management of individual R01 projects. For this effort we are requesting 5 years of support for 75% of Dr. Voas' time. ..
- Campuses selling alcohol--Profit of Problem?Robert Voas; Fiscal Year: 2005....
- Lowering the drinking age: The New Zealand exampleRobert Voas; Fiscal Year: 2005..abstract_text> ..
- EVALUATION OF EFFORTS TO REDUCE BORDER BINGE DRINKINGRobert Voas; Fiscal Year: 2002..El Paso/Juarez, a border town with a similar border-binge drinking problem will, serve as a comparison site. ..
- ENVIRONMENTAL PREVENTION OF COLLEGE ALCOHOL PROBLEMSRobert Voas; Fiscal Year: 2003..abstract_text> ..
- Drivers with Alcohol Use Disorders: At high risk for crashes?Robert B Voas; Fiscal Year: 2010..It will determine the prevalence of drivers with alcohol use disorders in traffic crashes and provide information to policymakers concerned with treatment and prevention programs. ..
- Campuses selling alcohol--Profit of Problem?Robert Voas; Fiscal Year: 2001....
- ENHANCING ALCOHOL INTERLOCK EFFECTS ON 1ST DUI OFFENDERSRobert Voas; Fiscal Year: 2004..This research builds on experience gained in a 5-year RO1-funded program in Alberta, Canada. ..
- Improving Care Continuity in Drug Abuse TreatmentMaxine L Stitzer; Fiscal Year: 2010..Overall, the project will provide valuable new data that can be used by policy makers to select treatment transition options that will maximize continuity of care within a drug abuse treatment services delivery system. ..
- RECOVERY HOUSING AND DRUG ABUSE TREATMENT OUTCOMESMaxine Stitzer; Fiscal Year: 2005..Thus, the project has both scientific value for services research and practical value for clinical application. ..
- TREATMENT FOR DUALLY DEPENDENT METHADONE PATIENTSNancy Petry; Fiscal Year: 2002....
- SOCIETY FOR RESEARCH ON NICOTINE AND TOBACCO ANN MEETINGMaxine Stitzer; Fiscal Year: 2002..Partial support of this meeting by NIDA would further highlight the agency's commitment to the importance of nicotine and tobacco research. ..
- Employment-Based Addiction PharmacotherapyKenneth Silverman; Fiscal Year: 2009..abstract_text> ..
- AFTERCARE FOR SUBSTANCE ABUSERSJames McKay; Fiscal Year: 2008..The cost-effectiveness and benefit cost of each of the enhanced interventions will also be determined, through a collaboration with Dr. Michael French. [unreadable] [unreadable] [unreadable] [unreadable]..
- Contingency Management: Duration EffectsJohn Roll; Fiscal Year: 2007..This is timely, given the burgeoning rates of methamphetamine abuse being reported. ..
- Protective Influence of Residential Learning CommunitiesSEAN MCCABE; Fiscal Year: 2006..At each measurement point, participants will complete a set of measures that assess substance use behaviors and constructs addressed by RLCs. ..
- Effectiveness of extended treatments for drug dependenceJames R McKay; Fiscal Year: 2010..Other analyses will test mediation hypotheses, examine potential moderator effects, and test the impact of disease management on HIV risk behaviors. ..
- Epidemiology of Prescription Drug Abuse in the United StatesSEAN MCCABE; Fiscal Year: 2007..It will help identify risk factors for substance abuse. Most importantly, the findings will provide guidance for the prevention, assessment, and treatment of prescription drug abuse. [unreadable] [unreadable]..
- A REINFORCEMENT-BASED THERAPEUTIC WORKPLACEKenneth Silverman; Fiscal Year: 2006..This research could provide firm scientific foundation for the dissemination of Therapeutic Workplace businesses in the long-term treatment of cocaine addiction and unemployment. ..
- Alcohol in Aviation and Motor CarriersGuohua Li; Fiscal Year: 2010..Findings from theproposed research couldprovide much-neededscientific evidence for informing important policy decisions relevant to transportation safety andprotection of the traveling public. ..
- Counseling for Primary Care Office-Based BuprenorphineDavid Fiellin; Fiscal Year: 2009..The results of this study will help define the role of professional evidence-based drug counseling in expanding access to treatment with Bup. ..
- Effectiveness of Extended Telephone MonitoringJames McKay; Fiscal Year: 2007..Economic analyses will determine the cost-effectiveness and benefit-cost of TMC and TMF relative to TAU, andto ach other. ..
- Treatment System Impact & Outcomes of Proposition 36Yih Ing Hser; Fiscal Year: 2006..The project will produce recommendations to improve treatment strategies and inform future policy and practice at the national, state, and local levels. ..
- Reducing Cocaine/Heroin Abuse with SR-Amphetamine and BuprenorphineMark Greenwald; Fiscal Year: 2009..The innovative aims, rigorous methods and clinical/public health significance of this project (i.e. whether SR-AMP has potential efficacy for reducing cocaine use) is highly concordant with this RFA. ..
- AFTERCARE FOR COCAINE PATIENTS--EFFECTIVENESS AND COSTSJames McKay; Fiscal Year: 2001..However, it is expected that MIN aftercare will be cost-effective for low problem severity ("good prognosis") patients, whereas IND aftercare will be cost-effective for high problem severity ("poor prognosis") patients. ..
- A THERAPEUTIC WORKPLACE FOR HOMELESS ALCOHOLICSKenneth Silverman; Fiscal Year: 2004..abstract_text> ..
- Effectiveness and Costs of Enhanced Cocaine TreatmentsJames McKay; Fiscal Year: 2005..voucher reinforcement. Additional analyses will identify predictors of response to the TAU+V and TAU+S conditions, and test predictions regarding possible mechanisms of action. ..
- Readiness for Implementation of Research to PracticeYih Ing Hser; Fiscal Year: 2004..abstract_text> ..
- Sexual Orientation, Substance Use and Mental HealthSEAN MCCABE; Fiscal Year: 2008..unreadable] [unreadable] [unreadable] [unreadable]..
- ADOLESCENT SMOKING CESSATIONJohn Roll; Fiscal Year: 2002..Secondarily, the proposed study will provide valuable information on the nicotine withdrawal syndrome in adolescents, a topic about which relatively little is known. ..
- THERAPEUTIC WORKPLACE TO PREVENT HIV TRANSMISSIONKenneth Silverman; Fiscal Year: 2003..abstract_text> ..
- Nonmedical Prescription Drug Use among College StudentsSEAN MCCABE; Fiscal Year: 2005..Findings from this research will have important implications for the understanding of the epidemiology, prevention and treatment of prescription drug abuse. ..
- A 12 YEAR FOLLOW UP OF A COCAINE DEPENDENT SAMPLEYih Ing Hser; Fiscal Year: 2003..abstract_text> ..
- A Long-term Follow-up Study of Drug-Dependent Mothers and ChildrenYih Ing Hser; Fiscal Year: 2010..The study will also lay the foundation for future in-depth investigation of the children of these mothers with histories of substance abuse. ..
- Human Methamphetamine Use: A ModelJohn Roll; Fiscal Year: 2002..Studies using laboratory models of human drug use can inform subsequent clinical trials and help to focus them on those variables which are likely to be important. ..
- Human Behavorial Pharmacology of GHBJohn Roll; Fiscal Year: 2002....
- DRUG ABUSE: EPIDEMIOLOGY, TREATMENT PROCESS, & OUTCOMESYih Ing Hser; Fiscal Year: 2003..The applicant also expects to grow professionally as Associate Director of the UCLA Drug Abuse Research Center. ..
- Reducing HIV/AIDS and Drug Abuse: Linking Compulsory Rehabilitation to Methadone Yih Ing Hser; Fiscal Year: 2008..If proven effective, the program can be widely applied in China and in other parts of the world to reduce heroin use and related HIV risk behaviors. [unreadable] [unreadable] [unreadable]..
- Behavior Change: Reinforcemnt Schedule EffectsJohn Roll; Fiscal Year: 2006..Based on the widespread success of contingency management across many different applications, we believe that the results of the proposed study will have 9enerality beyond the field of substance abuse treatment. ..
- Human Laboratory Model of Cocaine Treatment: Behavioral Economic AnalysisMark K Greenwald; Fiscal Year: 2010....
- Topiramate for alcohol and cocaine dependenceKyle Kampman; Fiscal Year: 2008..abstract_text> ..
- TRANSFERRING DRUG ABUSE TREATMENT AND ASSESSMENT RESOURCD Simpson; Fiscal Year: 2008..abstract_text> ..
- Prescription Drug Abuse Among College StudentsSEAN MCCABE; Fiscal Year: 2005....
- Alcohol and Injury: New Knowledge from ER StudiesCheryl Cherpitel; Fiscal Year: 2005....
- Effective Treatment for Prescription Opioid AbuseSTACEY SIGMON; Fiscal Year: 2009..Development of efficacious treatments for this emerging population will help to reduce the vast economic and societal costs associated with prescription opioid abuse. ..
- Trazodone for Sleep Disturbance - Early Alcohol RecoveryPeter Friedmann; Fiscal Year: 2004..Our extensive contacts with community agencies and substance abuse treatment facilities should enhance follow-up rates. ..
- Naltrexone for Bipolar Disorder and Alcohol DependenceE Sherwood Brown; Fiscal Year: 2006..Alcohol use is the primary outcome, and alcohol craving is the secondary outcome. Manic and depressive symptom severity and the relationship between changes in alcohol use and changes in mood will be expIored. ..
- Consequences of Prenatal Cocaine Exposure in AdolescenceVirginia Delaney Black; Fiscal Year: 2006..The proposed research will provide data critical to understanding the impact of prenatal cocaine exposure in adolescence, and to shape future studies of problem behaviors in late adolescence and early adulthood. ..
- Diffusion of Drug Prevention Curricula NationwideChristopher Ringwalt; Fiscal Year: 2007..abstract_text> ..
- Promoting Fidelity Using Remote and Onsite SupportChristopher Ringwalt; Fiscal Year: 2006..Study results will inform the prevention field concerning the potential for personalized coaching and technical assistance to promote curriculum fidelity and affect key student-level mediating variables. ..
- Fetal and Infant Neurobehavior in Opiate Dependent WomenLauren Jansson; Fiscal Year: 2009..Information gained from this proposal has the potential to significantly impact the way in which we treat the difficult and high-risk population of opiate dependent pregnant women. ..
- CHARACTERIZING PSYCHOACTIVE EFFECTS OF INHALANTSJames Zacny; Fiscal Year: 2004..In short, in our two proposed series of studies, we are developing a human laboratory model of inhalant abuse by studying potential determinants of abuse liability of inhalants (volatile and gaseous) in healthy volunteers. ..
- METHADONE, BUPRENORPHINE AND FETAL DEVELOPMENTLauren Jansson; Fiscal Year: 2004..Upon completing the 5-year funding period, Dr. Jansson plans to have written an RO1 grant application to pursue research ideas identified during KO8 funding. ..
- Abuse-Related Effects of Opioids and Adjuvant Drug Used by Chronic Pain PatientsJames P Zacny; Fiscal Year: 2010..g., muscle relaxant B) would be the preferred drug to prescribe when treating chronic nonmalignant pain patients. ..
- "Engaging Moms." An Intervention for Family Drug CourtGAYLE DAKOF; Fiscal Year: 2006..abstract_text> ..
- Pathways From Subtypes of Aggression to Substance UsePaula Fite; Fiscal Year: 2007....
- Behavior Therapy Development of Group CM in Methadone TxKimberly Kirby; Fiscal Year: 2008..e., number of behaviors targeted, frequency of urine testing). While developing this Group CM intervention will not by itself result in improved dissemination of CM, it is a critical first step in this direction. ..