neuronavigation

Summary

Summary: Intraoperative computer-assisted 3D navigation and guidance system generally used in neurosurgery for tracking surgical tools and localize them with respect to the patient's 3D anatomy. The pre-operative diagnostic scan is used as a reference and is transferred onto the operative field during surgery.

Top Publications

  1. ncbi Resection of malignant brain tumors in eloquent cortical areas: a new multimodal approach combining 5-aminolevulinic acid and intraoperative monitoring
    Guenther C Feigl
    Department of Neurosurgery, University of Tuebingen Medical Center, Tuebingen, Germany
    J Neurosurg 113:352-7. 2010
  2. ncbi Transcranial magnetic stimulation and the challenge of coil placement: a comparison of conventional and stereotaxic neuronavigational strategies
    Roland Sparing
    Department of Medicine, Institute of Neuroscience and Biophysics, Research Center Juelich, Juelich, Germany
    Hum Brain Mapp 29:82-96. 2008
  3. ncbi Diffusion tensor-based fiber tracking and intraoperative neuronavigation for the resection of a brainstem cavernous angioma
    Xiaolei Chen
    Department of Neurosurgery, University of Erlangen Nurnberg, 91054 Erlangen, Germany
    Surg Neurol 68:285-91; discussion 291. 2007
  4. ncbi Multimodal navigation in the functional microsurgical resection of intrinsic brain tumors located in eloquent motor areas: role of tractography
    José M González-Darder
    Department of Neurosurgery, Hospital Clinico Universitario, Servicio Valenciano de Salud, 46010 Valencia, Spain
    Neurosurg Focus 28:E5. 2010
  5. ncbi Image-guided removal of supratentorial cavernomas in critical brain areas: application of neuronavigation and intraoperative magnetic resonance imaging
    J Gralla
    Department of Neurosurgery, University Erlangen Nurnberg, Erlangen, Germany
    Minim Invasive Neurosurg 46:72-7. 2003
  6. ncbi rTMS for the treatment of tinnitus: the role of neuronavigation for coil positioning
    B Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
    Neurophysiol Clin 40:45-58. 2010
  7. ncbi Virtual temporal bone: an interactive 3-dimensional learning aid for cranial base surgery
    Ralf A Kockro
    Department of Neurosurgery, University of Mainz, Mainz, Germany
    Neurosurgery 64:216-29; discussion 229-30. 2009
  8. ncbi Integration of functional neuronavigation and intraoperative MRI in surgery for drug-resistant extratemporal epilepsy close to eloquent brain areas
    Björn Sommer
    Department of Neurosurgery, University Hospital Erlangen, Erlangen 91054, Germany
    Neurosurg Focus 34:E4. 2013
  9. pmc Endoscopic transnasal resection of anterior skull base malignancy with a novel 3D endoscope and neuronavigation
    P Castelnuovo
    Dept of Otorhinolaryngology, Azienda Ospedaliero Universitaria, Ospedale di Circolo e Fondazione Macchi, University of Varese, Italy
    Acta Otorhinolaryngol Ital 32:189-91. 2012
  10. ncbi Multimodal navigation integrated with imaging
    Christopher Nimsky
    Department of Neurosurgery, University Marburg, Baldingerstrasse, 35033 Marburg, Germany
    Acta Neurochir Suppl 109:207-14. 2011

Detail Information

Publications289 found, 100 shown here

  1. ncbi Resection of malignant brain tumors in eloquent cortical areas: a new multimodal approach combining 5-aminolevulinic acid and intraoperative monitoring
    Guenther C Feigl
    Department of Neurosurgery, University of Tuebingen Medical Center, Tuebingen, Germany
    J Neurosurg 113:352-7. 2010
    ....
  2. ncbi Transcranial magnetic stimulation and the challenge of coil placement: a comparison of conventional and stereotaxic neuronavigational strategies
    Roland Sparing
    Department of Medicine, Institute of Neuroscience and Biophysics, Research Center Juelich, Juelich, Germany
    Hum Brain Mapp 29:82-96. 2008
    ..Very consistent results were also obtained with the "probabilistic" approach. In view of these findings, we discuss the methods and special characteristics of each localization strategy...
  3. ncbi Diffusion tensor-based fiber tracking and intraoperative neuronavigation for the resection of a brainstem cavernous angioma
    Xiaolei Chen
    Department of Neurosurgery, University of Erlangen Nurnberg, 91054 Erlangen, Germany
    Surg Neurol 68:285-91; discussion 291. 2007
    ..Integration of the tractography into neuronavigation system makes it possible for the intraoperative visualization of the major fiber tracts...
  4. ncbi Multimodal navigation in the functional microsurgical resection of intrinsic brain tumors located in eloquent motor areas: role of tractography
    José M González-Darder
    Department of Neurosurgery, Hospital Clinico Universitario, Servicio Valenciano de Salud, 46010 Valencia, Spain
    Neurosurg Focus 28:E5. 2010
    ....
  5. ncbi Image-guided removal of supratentorial cavernomas in critical brain areas: application of neuronavigation and intraoperative magnetic resonance imaging
    J Gralla
    Department of Neurosurgery, University Erlangen Nurnberg, Erlangen, Germany
    Minim Invasive Neurosurg 46:72-7. 2003
    ..The study indicates that the application of neuronavigation allows surgery on supratentorial cavernous hemangiomas in critical brain areas with low morbidity...
  6. ncbi rTMS for the treatment of tinnitus: the role of neuronavigation for coil positioning
    B Langguth
    Department of Psychiatry and Psychotherapy, University of Regensburg, Universitaetsstrasse 84, 93053 Regensburg, Germany
    Neurophysiol Clin 40:45-58. 2010
    ....
  7. ncbi Virtual temporal bone: an interactive 3-dimensional learning aid for cranial base surgery
    Ralf A Kockro
    Department of Neurosurgery, University of Mainz, Mainz, Germany
    Neurosurgery 64:216-29; discussion 229-30. 2009
    ..We have developed an interactive virtual model of the temporal bone for the training and teaching of cranial base surgery...
  8. ncbi Integration of functional neuronavigation and intraoperative MRI in surgery for drug-resistant extratemporal epilepsy close to eloquent brain areas
    Björn Sommer
    Department of Neurosurgery, University Hospital Erlangen, Erlangen 91054, Germany
    Neurosurg Focus 34:E4. 2013
    The authors performed a retrospective study to assess the impact of functional neuronavigation and intraoperative MRI (iMRI) on surgery of extratemporal epileptogenic lesions on postsurgical morbidity and seizure control.
  9. pmc Endoscopic transnasal resection of anterior skull base malignancy with a novel 3D endoscope and neuronavigation
    P Castelnuovo
    Dept of Otorhinolaryngology, Azienda Ospedaliero Universitaria, Ospedale di Circolo e Fondazione Macchi, University of Varese, Italy
    Acta Otorhinolaryngol Ital 32:189-91. 2012
    ..by means of a four-hand binarial endoscopic transnasal resection using a 3D endoscopic system and neuronavigation. Surgery was completed in 5 hours without significant complications...
  10. ncbi Multimodal navigation integrated with imaging
    Christopher Nimsky
    Department of Neurosurgery, University Marburg, Baldingerstrasse, 35033 Marburg, Germany
    Acta Neurochir Suppl 109:207-14. 2011
    ..With the help of intraoperative imaging navigation data can be updated, so that brain shift can be compensated for and initially missed tumor remnants can be localized reliably...
  11. ncbi Did survival improve after the implementation of intraoperative neuronavigation and 3D ultrasound in glioblastoma surgery? A retrospective analysis of 192 primary operations
    C A Sæther
    Faculty of Medicine, Norwegian University of Science and Technology, Trondheim, Norway
    J Neurol Surg A Cent Eur Neurosurg 73:73-8. 2012
    ..The aim of the present study was to examine if the introduction of 3D ultrasound and neuronavigation (i. e., the SonoWand® system) may have had an impact on overall survival.
  12. ncbi Fluorescence and image guided resection in high grade glioma
    Pier Paolo Panciani
    Division of Neurosurgery, Department of Neuroscience, University of Turin, Via Cherasco 15 10126 Torino, Italy
    Clin Neurol Neurosurg 114:37-41. 2012
    ..Furthermore, the role of 5-aminolevulinc acid and neuronavigation were reviewed...
  13. ncbi Brain shift compensation and neurosurgical image fusion using intraoperative MRI: current status and future challenges
    Daniela Kuhnt
    Department of Neurosurgery, University of Marburg, Germany
    Crit Rev Biomed Eng 40:175-85. 2012
    ..The following article summarizes the work flow and clinical impact of iMRI and functional navigation, as well as current problems and possible solutions...
  14. ncbi Volumetric assessment of glioma removal by intraoperative high-field magnetic resonance imaging
    Christopher Nimsky
    Department of Neurosurgery, University Erlangen Nurnberg, Erlangen, Germany
    Neurosurgery 55:358-70; discussion 370-1. 2004
    ..To investigate the contribution of high-field intraoperative magnetic resonance imaging (iMRI) for further reduction of tumor volume in glioma surgery...
  15. ncbi Clinical evaluation and follow-up outcome of presurgical plan by Dextroscope: a prospective controlled study in patients with skull base tumors
    De L Yang
    Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China
    Surg Neurol 72:682-9; discussion 689. 2009
    ....
  16. ncbi Virtual reality presurgical planning for cerebral gliomas adjacent to motor pathways in an integrated 3-D stereoscopic visualization of structural MRI and DTI tractography
    Tian ming Qiu
    Shanghai Neurosurgical Center, Department of Neurosurgery, Huashan Hospital, Shanghai Medical School, Fudan University, Shanghai, 200040, People s Republic of China
    Acta Neurochir (Wien) 152:1847-57. 2010
    ..The potential value of its clinical application was evaluated...
  17. ncbi Endoscopic management of arachnoid cysts: an advancing technique
    Konstantina Karabatsou
    Department of Neurosurgery, Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
    J Neurosurg 106:455-62. 2007
    ..cysts using endoscopic techniques and, more recently, the use of these techniques in combination with neuronavigation systems...
  18. ncbi Characterizing magnetic spike sources by using magnetoencephalography-guided neuronavigation in epilepsy surgery in pediatric patients
    Koji Iida
    Division of Neurology, The Hospital for Sick Children and University of Toronto, Ontario, Canada
    J Neurosurg 102:187-96. 2005
    The authors sought to validate magnetoencephalography spike sources (MEGSSs) in neuronavigation during epilepsy surgery in pediatric patients.
  19. ncbi Clinical evaluation and follow-up outcome of diffusion tensor imaging-based functional neuronavigation: a prospective, controlled study in patients with gliomas involving pyramidal tracts
    Jin Song Wu
    Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China
    Neurosurgery 61:935-48; discussion 948-9. 2007
    To evaluate diffusion tensor imaging (DTI)-based functional neuronavigation in surgery of cerebral gliomas with pyramidal tract (PT) involvement with respect to both perioperative assessment and follow-up outcome.
  20. ncbi Course of brain shift during microsurgical resection of supratentorial cerebral lesions: limits of conventional neuronavigation
    M H T Reinges
    Department of Neurosurgery, University of Technology RWTH Aachen, Germany
    Acta Neurochir (Wien) 146:369-77; discussion 377. 2004
    ..The authors have conducted a prospective study to evaluate the amount and course of brain shift during microsurgical removal of supratentorial cerebral lesions, and to assess factors which potentially influence these shifts...
  21. ncbi Neuronavigation: concept, techniques and applications
    O Ganslandt
    Department of Neurosurgery, University of Erlangen Nuremberg, Schwabachanlage 6, 91054, Erlangen, Germany
    Neurol India 50:244-55. 2002
    b>Neuronavigation provides intraoperative orientation to the surgeon, helps in planning a precise surgical approach to the targetted lesion and defines the surrounding neurovascular structures...
  22. ncbi Functional brain mapping and its applications to neurosurgery
    Suzanne Tharin
    Department of Neurosurgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts 02115, USA
    Neurosurgery 60:185-201; discussion 201-2. 2007
    ..Along the way, new insights on fundamental processes such as the biology of tumors and brain plasticity are likely to be revealed...
  23. ncbi Fiber-tracking does not accurately estimate size of fiber bundle in pathological condition: initial neurosurgical experience using neuronavigation and subcortical white matter stimulation
    Manabu Kinoshita
    Department of Neurosurgery, Osaka University Medical School, Yamadaoka, 2 2, Suita, Osaka 565 0871, Japan
    Neuroimage 25:424-9. 2005
    ..validation of tractography in human subjects harboring brain tumors by comparing the results produced by neuronavigation and electrical white matter stimulation in two patients with gliomas in the eloquent area...
  24. ncbi Intraoperative visualization for resection of gliomas: the role of functional neuronavigation and intraoperative 1.5 T MRI
    Christopher Nimsky
    Department of Neurosurgery, University Erlangen Nuremberg, Erlangen, Germany
    Neurol Res 28:482-7. 2006
    To investigate how functional neuronavigation and intraoperative high-field magnetic resonance imaging (MRI) influence glioma resection.
  25. ncbi Integrating magnetic resonance imaging postprocessing results into neuronavigation for electrode implantation and resection of subtle focal cortical dysplasia in previously cryptogenic epilepsy
    Jörg Wellmer
    Department of Epileptology, University Hospital Bonn, Sigmund Freud Strasse 25, 53105 Bonn, Germany
    Neurosurgery 66:187-94; discussion 194-5. 2010
    ..We describe how the results of normal database-based MRI postprocessing can be used to guide stereotactic electrode implantation and subsequent resection of lesions that are suspected to be FCDs...
  26. ncbi Multimodal image fusion in ultrasound-based neuronavigation: improving overview and interpretation by integrating preoperative MRI with intraoperative 3D ultrasound
    Frank Lindseth
    SINTEF Unimed, Ultrasound, Trondheim, Norway
    Comput Aided Surg 8:49-69. 2003
    ..investigated alternative ways to integrate intraoperative 3D ultrasound images and preoperative MR images in the same 3D scene for visualizing brain shift and improving overview and interpretation in ultrasound-based neuronavigation.
  27. ncbi Electromagnetic-guided neuroendoscopy in the pediatric population
    Meharpal Sangra
    Department of Neurosurgery, Royal Liverpool Children s Hospital National Health Service Trust, Liverpool, United Kingdom
    J Neurosurg Pediatr 3:325-30. 2009
    ..The authors present their series to date, define its role, and discuss its advantages over other forms of image-guided navigation...
  28. ncbi Pre-surgical planning and MR-tractography utility in brain tumour resection
    A Romano
    Department of Neuroradiology, S Andrea Hospital, University Sapienza, Rome, Italy
    Eur Radiol 19:2798-808. 2009
    ..1) to evaluate the possible identification of trajectories of fibre tracts, (2) to examine the useful of a neuronavigation system for presurgical planning, (3) to assess pre- and post-surgery patients' clinical condition and (4) to ..
  29. ncbi Visualization of the eloquent motor system by integration of MEG, functional, and anisotropic diffusion-weighted MRI in functional neuronavigation
    Kyousuke Kamada
    Department of Neurosurgery, Hokkaido University, Sapporo, Japan
    Surg Neurol 59:352-61; discussion 361-2. 2003
    ..we visualized the eloquent motor system including the somatosensory-motor cortex and corticospinal tract on a neuronavigation system, integrating magnetoencephalography (MEG), functional magnetic resonance imaging (fMRI), and ..
  30. ncbi Fiducial versus nonfiducial neuronavigation registration assessment and considerations of accuracy
    Wolfgang K Pfisterer
    Neurosurgery Research Laboratory, Division of Neurological Surgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona, USA
    Neurosurgery 62:201-7; discussion 207-8. 2008
    ..e., to determine the accuracy of registration techniques with and without FMs by examining the extent of agreement between the system-generated predicted value and physical measured values...
  31. ncbi Utility of neuronavigation and neuromonitoring in epilepsy surgery
    Scellig S D Stone
    Department of Surgery, Division of Neurosurgery, The Hospital for Sick Children, Toronto, Ontario, Canada
    Neurosurg Focus 25:E17. 2008
    ..In particular, image-based neuronavigation and electrophysiological neuromonitoring represent versatile and informative modalities that can assist a ..
  32. ncbi Sensor-based neuronavigation: evaluation of a large continuous patient population
    Bjoern Kuehn
    Klinik für Neurochirurgie, Charite Universitatsmedizin Berlin, Hindenburgdamm 30, 12203 Berlin, Germany
    Clin Neurol Neurosurg 110:1012-9. 2008
    Navigation systems enable neurosurgeons to guide operations with imaging data. Sensor-based neuronavigation uses an electromagnetic field and sensors to measure the positions of the patient's brain anatomy and the surgical instruments...
  33. ncbi Image fusion of MR images and real-time ultrasonography: evaluation of fusion accuracy combining two commercial instruments, a neuronavigation system and a ultrasound system
    J R Schlaier
    Department of Neurosurgery, University of Regensburg, Franz Josef Strauss Allee 11, 93052 Regensburg, Germany
    Acta Neurochir (Wien) 146:271-6; discussion 276-7. 2004
    ..The aim of our study was to evaluate MRI/Ultrasonography fusion accuracy depending on three ultrasonographic parameters...
  34. ncbi Three-dimensionally reconstructed magnetic source imaging and neuronavigation in pediatric epilepsy: technical note
    Stephanie A Holowka
    Department of Diagnostic Imaging, The Hospital for Sick Children, Toronto, Ontario, Canada
    Neurosurgery 55:1226. 2004
    To determine the role of reconstructing three-dimensional magnetic source imaging (MSI) data on cortical resections for children undergoing epilepsy surgery using neuronavigation.
  35. ncbi Impact of neuronavigation and image-guided extensive resection for adult patients with supratentorial malignant astrocytomas: a single-institution retrospective study
    M Kurimoto
    Department of Neurosurgery, Toyama Medical and Pharmaceutical University, 2630 Sugitani, Toyama 930 0194, Japan
    Minim Invasive Neurosurg 47:278-83. 2004
    b>Neuronavigation has become an effective therapeutic modality and is used routinely for intra-axial tumor removal...
  36. pmc Neuronavigation increases the physiologic and behavioral effects of low-frequency rTMS of primary motor cortex in healthy subjects
    S Bashir
    Berenson Allen Center for Noninvasive Brain Stimulation, Division of Cognitive Neurology, Department of Neurology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA
    Brain Topogr 24:54-64. 2011
    ..We aimed to assess whether neuronavigation enhances the physiologic and behavioral effects of low-frequency rTMS...
  37. ncbi Neurosurgical craniotomy localization using a virtual reality planning system versus intraoperative image-guided navigation
    Axel T Stadie
    Neurochirurgische Klinik und Poliklinik, Universitätsmedizin Mainz, Langenbeckstrasse 1, 55101 Mainz, Germany
    Int J Comput Assist Radiol Surg 6:565-72. 2011
    Accurate craniotomy placement is essential for frameless neuronavigation in minimally invasive neurosurgery. A craniotomy using virtual reality (VR) can be as accurate as neuronavigation.
  38. ncbi Influence of different registration modalities on navigation accuracy in ear, nose, and throat surgery depending on the surgical field
    Tanja D Grauvogel
    Department of Otorhinolaryngology Head and Neck Surgery, Albert Ludwigs University, Killianstrasse 5, 79106 Freiburg, Germany
    Laryngoscope 120:881-8. 2010
    ..The present study compared the registration and navigation accuracy of three different registration modalities in anatomical locations of special interest for ear, nose, and throat surgery...
  39. ncbi Classification and analysis of the errors in neuronavigation
    Man Ning Wang
    Digital Medical Research Center, Shanghai Medical School, Fudan University, and Shanghai Key Lab of Medical Image Computing and Computer Assisted Intervention, Shanghai, China
    Neurosurgery 68:1131-43; discussion 1143. 2011
    There are many different types of errors in neuronavigation, and the reasons and results of these errors are complex...
  40. ncbi A technical note on endonasal combined microscopic endoscopic with free head navigation technique of removal of pituitary adenomas
    Ossama Al-Mefty
    Department of Neurosurgery, University of Arkansas for Medical Sciences, 4301 W Markham, 507, Little Rock, AR 72205, USA
    Neurosurg Rev 33:243-8; discussion 248-9. 2010
    ....
  41. ncbi Supratentorial cavernomas in eloquent brain areas: application of neuronavigation and functional MRI in operative planning
    D Zotta
    Department of Neurosurgery, San Salvatore Hospital, L Aquila, Italy
    J Neurosurg Sci 49:13-9. 2005
    ..Aim of this study was to evaluate the usefulness of integration between standard magnetic resonance imaging (MRI) for neuronavigation and functional MRI (fMRI) in preoperative planning and intraoperative removal of cavernomas.
  42. ncbi Intraoperative MRI with integrated functional neuronavigation-guided resection of supratentorial cavernous malformations in eloquent brain areas
    Guo chen Sun
    Department of Neurosurgery, PLA General Hospital, 28 Fuxing Rd, Beijng 100853, China
    J Clin Neurosci 18:1350-4. 2011
    ..malformations in eloquent brain areas underwent surgery with the aid of intraoperative MRI (iMRI), functional neuronavigation, and electrocorticography (ECoG)...
  43. ncbi Intraoperative MRI and functional mapping
    Thomas Gasser
    Department of Neurosurgery, University of Duisburg Essen, Hufelandstr 55, 45147 Essen, Germany
    Acta Neurochir Suppl 109:61-5. 2011
    The integration of functional and anatomical data into neuronavigation is an established standard of care in many neurosurgical departments. Yet, this method has limitations as in most cases the data are acquired prior to surgery...
  44. ncbi Neuronavigation-guided focused ultrasound-induced blood-brain barrier opening: a preliminary study in swine
    K C Wei
    Department of Neurosurgery, Chang Gung University and Memorial Hospital, Taoyuan, Taiwan
    AJNR Am J Neuroradiol 34:115-20. 2013
    ..Here we propose the novel use of a neuronavigation system to guide the FUS-induced BBB opening procedure and investigate its feasibility in vivo in large animals...
  45. ncbi Neuronavigation and surgery of intracerebral tumours
    P W A Willems
    Department of Neurosurgery, University Medical Center, Utrecht, CX, The Netherlands
    J Neurol 253:1123-36. 2006
    ..Frameless stereotaxy, or neuronavigation, relies on one of several different localizing techniques to determine the position of an operative ..
  46. ncbi Technical refinements for validating functional MRI-based neuronavigation data by electrical stimulation during cortical language mapping
    F Signorelli
    Service de Neurochirurgie B, Hopital Neurologique, BP Lyon Monchat, 59 Boulevard Pinel, BP Lyon Monchat, 69394 Lyon Cedex 03, France
    Minim Invasive Neurosurg 46:265-8. 2003
    ..function by preoperative functional magnetic resonance imaging (fMRI), whose results were integrated into the neuronavigation device, and by intraoperative electrical stimulation mapping (ESM)...
  47. ncbi Brain surface reformatted images for fast and easy localization of perirolandic lesions
    Elke Hattingen
    Institute of Neuroradiology, Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    J Neurosurg 102:302-10. 2005
    ....
  48. ncbi Classical and real-time neuronavigation in pediatric neurosurgery
    Jonathan Roth
    Department of Pediatric Neurosurgery, Dana Children s Hospital, Tel Aviv Sourasky Medical Center, 64239 Tel Aviv, Israel
    Childs Nerv Syst 22:1065-71. 2006
    b>Neuronavigation has become a cornerstone of neurosurgery. Navigation systems are categorized into two main groups: those based on preoperative imaging and those based on real-time intraoperative acquired images.
  49. ncbi Navigated endoscopic surgery for multiloculated hydrocephalus in children
    Matthias Schulz
    Department of Pediatric Neurosurgery, Charite Universitatsmedizin Berlin, Germany
    J Neurosurg Pediatr 5:434-42. 2010
    ..In a retrospective study, the authors reviewed their experience with navigated endoscopy to treat multiloculated hydrocephalus in children...
  50. ncbi Neuronavigation: geneology, reality, and prospects
    Yavor Enchev
    Department of Neurosurgery, Medical University Sofia, Bulgaria
    Neurosurg Focus 27:E11. 2009
    Currently, neuronavigation is an indivisible and indispensable part of the neurosurgical reality with a significant potential impact in each neurosurgical procedure...
  51. ncbi Efficacy of endoport-guided endoscopic resection for deep-seated brain lesions
    Kwang Wook Jo
    Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University, School of Medicine, 50 Ir won dong, Kang Nam Ku, 135 71, Seoul, South Korea
    Neurosurg Rev 34:457-63. 2011
    ..determine the efficacy of endoport-guided endoscopic or microscopic removal for deep-seated lesions using the neuronavigation system. Between October 2008 and December 2009, 21 patients (17 men and 4 women; average age, 40...
  52. ncbi Functional neuronavigation and intraoperative MRI
    C Nimsky
    Department of Neurosurgery, University Erlangen Nurnberg, Erlangen, Germany
    Adv Tech Stand Neurosurg 29:229-63. 2004
    ..surgery is based on the combination of intraoperative magnetic resonance (MR) imaging with microscope-based neuronavigation, providing anatomical and functional guidance simultaneously...
  53. ncbi Endoscopic opening of the foramen of magendie using transaqueductal navigation for membrane obstruction of the fourth ventricle outlets. Technical note
    Pierluigi Longatti
    Neurosurgical Unit, Treviso Hospital, Padova University, Treviso, Italy
    J Neurosurg 105:924-7. 2006
    ..In these cases, endoscopic opening of the foramen of Magendie by transaqueductal navigation of the fourth ventricle is a suitable and feasible therapeutic option...
  54. ncbi Neuronavigation combined with electrophysiological monitoring for surgery of lesions in eloquent brain areas in 42 cases: a retrospective comparison of the neurological outcome and the quality of resection with a control group with similar lesions
    T Reithmeier
    Department of Neurosurgery, Academic Hospital Munich Bogenhausen, Technical University of Munich, Munich, Germany
    Minim Invasive Neurosurg 46:65-71. 2003
    ..radical resection of tumors in the area of the motor cortex via minimal craniotomy using a combination of neuronavigation and neurophysiological monitoring with direct electrical cortical stimulation and to compare retrospectively ..
  55. ncbi Use of 3D visualisation of medical images for planning and intraoperative localisation of superficial brain tumours: our experience
    Tilen Zele
    Faculty of Medicine, Institute of Pathophysiology, University of Ljubljana, Ljubljana, Slovenia
    Br J Neurosurg 24:555-60. 2010
    ..In the present article, we assessed the role, adequacy and application accuracy of intraoperative visual guidance based on the computer 3D visualisation of preoperative medical images in the surgery of superficial brain tumours...
  56. ncbi Functional magnetic resonance imaging and diffusion tensor tractography incorporated into an intraoperative 3-dimensional ultrasound-based neuronavigation system: impact on therapeutic strategies, extent of resection, and clinical outcome
    Erik Magnus Berntsen
    Department of Circulation and Medical Imaging, Faculty of Medicine, Norwegian University of Science and Technology, Department of Medical Imaging, St Olavs Hospital, Trondheim, Norway
    Neurosurgery 67:251-64. 2010
    Functional neuronavigation with intraoperative 3-dimensional (3D) ultrasound may facilitate safer brain lesion resections than conventional neuronavigation.
  57. ncbi Combination of functional magnetic resonance imaging-guided neuronavigation and intraoperative cortical brain mapping improves targeting of motor cortex stimulation in neuropathic pain
    Benoit Pirotte
    Department of Neurosurgery, Erasme Hospital, Universite Libre de Bruxelles, Brussels, Belgium
    Neurosurgery 56:344-59; discussion 344-59. 2005
    ....
  58. ncbi Updating of neuronavigation based on images intraoperatively acquired with a mobile computerized tomographic scanner: technical note
    N Nakao
    Department of Neurological Surgery, Wakayama Medical University, Wakayama, Japan
    Minim Invasive Neurosurg 46:117-20. 2003
    ....
  59. ncbi Carotid artery visualization during anterior skull base surgery: a novel protocol for neuronavigation
    Brent M McGrath
    Department of Surgery Neurosurgery, Dalhousie University, 1796 Summer Street, Halifax, NS, B3H 3A7, Canada
    Pituitary 13:215-22. 2010
    ..the Canadian and Austrian experiences using a novel protocol integrating MR angiography (MRA) into surgical neuronavigation to provide superior visualization of the carotid arteries...
  60. ncbi Brain tumour surgery in the vicinity of short-term memory representation--results of neuronavigation using fMRI images
    V Braun
    Department of Neurosurgery, Ev Jung Stilling Krankenhaus, Siegen, Germany
    Acta Neurochir (Wien) 148:733-9. 2006
    ..Obviously this information must be integrated into cranial neuronavigation for an appropriate intra-operative use...
  61. ncbi Intraoperative MRI for interventional neurosurgical procedures and tumor resection control in children
    Paul Kremer
    Neurosurgical Department, University of Heidelberg, Heidelberg, Germany
    Childs Nerv Syst 22:674-8. 2006
    ..Whereas most procedures with ioMRI were carried out in adults, we summarize 7 years of experience using ioMRI in children for interventional neurosurgical procedures or for tumor resection control...
  62. ncbi Accuracy of intraoperative registration during electromagnetic neuronavigation in intracranial procedures performed in children
    Sławomir Barszcz
    Department of Neurosurgery, Children s Memorial Health Institute, Warsaw
    Neurol Neurochir Pol 41:122-7. 2007
    ..The aim of the study was to evaluate registration accuracy in an electromagnetic navigation system applied to image-guided intracranial procedures in children...
  63. ncbi Use of a compact intraoperative low-field magnetic imager in pediatric neurosurgery
    Amer F Samdani
    Department of Neurosurgery, New Jersey Medical School, 90 Bergen Street, Newark, NJ 07103, USA
    Childs Nerv Syst 21:108-13; discussion 114. 2005
    ..The majority of investigations on the utility of and indications for intraoperative magnetic resonance imaging (iMRI) have been in adult patients. We report our initial experience utilizing low-field iMRI in pediatric patients...
  64. ncbi Advanced neuronavigation in skull base tumors and vascular lesions
    V Rohde
    Department of Neurosurgery, University of Aachen, Aachen, Germany
    Minim Invasive Neurosurg 48:13-8. 2005
    ..The purpose of this study was to describe the usefulness of recent advances of neuronavigational technology in the management of skull base tumors and of vascular lesions, treated via a skull base approach...
  65. ncbi Clinical impact of integrated functional neuronavigation and subcortical electrical stimulation to preserve motor function during resection of brain tumors
    Nobuhiro Mikuni
    Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan
    J Neurosurg 106:593-8. 2007
    The authors evaluated the clinical impact of combining functional neuronavigation with subcortical electrical stimulation to preserve motor function following the removal of brain tumors.
  66. ncbi Comparison of the reliability of brain lesion localization when using traditional and stereotactic image-guided techniques: a prospective study
    Carl J Spivak
    Division of Neurosurgery, Royal University Hospital, University of Saskatchewan, Saskatoon, Saskatchewan, Canada
    J Neurosurg 103:424-7. 2005
    ..Even though these systems have been found to be accurate, no studies have been conducted to investigate whether the systems provide improved localization accuracy compared with traditional methods...
  67. ncbi Cranial surgery with an expanded compact intraoperative magnetic resonance imager. Technical note
    Michael Schulder
    Department of Neurological Surgery, New Jersey Medical School, Newark, New Jersey 07103 2499, USA
    J Neurosurg 104:611-7. 2006
    ..Greater ease of positioning resulted in a decrease in added time in the OR and encouraged a larger number of imaging sessions...
  68. ncbi Application of neuronavigation system to brain tumor surgery with clinical experience of 420 cases
    T Y Jung
    Department of Neurosurgery, Chonnam National University Research Institute of Medical Sciences, Chonnam National University Hwasun Hospital and Medical School, Gwangju, Republic of Korea
    Minim Invasive Neurosurg 49:210-5. 2006
    A new era of neurosurgery has recently been unveiled with the advent of image-guided surgery. The use of neuronavigation is beginning to have a significant impact on a variety of intracranial procedures...
  69. ncbi Surgical target selection in cerebral glioma surgery: linking methionine (MET) PET image fusion and neuronavigation
    K Roessler
    Department of Neurosurgery, Medical University of Vienna, Vienna, Austria
    Minim Invasive Neurosurg 50:273-80. 2007
    ..The objective of this study was to investigate the histological correlate of (11)C-methionine (MET) PET uptake of brain gliomas by image fusion for navigated surgery...
  70. ncbi [Neuronavigation in transnasal endoscopic paranasal sinuses and cranial base surgery: comparison of the optical and electromagnetic systems]
    Andrzej Sieskiewicz
    Klinika Otolaryngologii Uniwersytetu Medycznego w Białymstoku
    Otolaryngol Pol 63:256-60. 2009
    ..The aim of this study was to compare (as basing on our own clinical experience), the advantages and limitations of the optical and electromagnetic neuronavigation systems.
  71. ncbi Intraoperative neurophysiological monitoring in an open low-field magnetic resonance imaging system: clinical experience and technical considerations
    Andrea Szelenyi
    Department of Neurosurgery, Johann Wolfgang Goethe University Hospital, Frankfurt, Germany
    Neurosurgery 63:268-75; discussion 275-6. 2008
    ..Methodological aspects and technical adaptations for this combination of methods and the experience in 29 patients with tumors in the central region are reported...
  72. ncbi Optimal transcranial magnetic stimulation coil placement for targeting the dorsolateral prefrontal cortex using novel magnetic resonance image-guided neuronavigation
    Pablo M Rusjan
    PET Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada
    Hum Brain Mapp 31:1643-52. 2010
    ..Our findings also suggest that the '10-20 method' is superior to the '5-cm method' in reducing inter-subject variability and that electrode F5 should be the stimulation location of choice when MRI co-registration is not available...
  73. ncbi Functional magnetic resonance imaging-integrated neuronavigation: correlation between lesion-to-motor cortex distance and outcome
    Rene Krishnan
    Department of Neurosurgery, Johann Wolfgang Goethe University, Frankfurt am Main, Germany
    Neurosurgery 55:904-14; discusssion 914-5. 2004
    The integration of functional magnetic resonance imaging (fMRI) data into neuronavigation is a new concept for surgery adjacent to the motor cortex. However, the clinical value remains to be defined...
  74. ncbi Automated three-dimensional volume rendering of helical computed tomographic angiography for aneurysms: an advanced application of neuronavigation technology
    Lucia Benvenuti
    Department of Neurosurgery, Livorno City Hospital, Livorno, Italy
    Neurosurgery 57:69-77; discussion 69-77. 2005
    ....
  75. ncbi Brain surgery in a stereoscopic virtual reality environment: a single institution's experience with 100 cases
    Paolo Ferroli
    Department of Neurosurgery, Fondazione Istituto Neurologico Carlo Besta, Milan, Italy
    Neurosurgery 67:ons79-84; discussion ons84. 2010
    ..A comprehensive understanding of the spatial relationships between intracranial anatomy and pathological features is a crucial element in neurosurgical planning...
  76. ncbi Intraoperative localization of subcortical brain lesions
    V Esposito
    Universita degli Studi di Roma Sapienza, Cattedra di Neurochirurgia IRCCS Neuromed, Pozzilli, Italy
    Acta Neurochir (Wien) 150:537-42; discussion 543. 2008
    ..We have developed MRI-based corticotopography (MRI-bct), to localize lesions during surgery, using simple, non-dedicated equipment, to match a three-dimensional reconstruction with the corresponding appearance of the brain cortex...
  77. ncbi Use of a minimally invasive tubular retraction system for deep-seated tumors in pediatric patients
    Pablo F Recinos
    Division of Pediatric Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 44195, USA
    J Neurosurg Pediatr 7:516-21. 2011
    ..The authors describe their experience utilizing a new tubular retractor system specifically designed for cranial applications in conjunction with frameless neuronavigation.
  78. ncbi CT-guided neurosurgery: preliminary experience
    G Broggi
    Department of Neurosurgery, Istituto Nazionale Neurologico C Besta, Milan, Italy
    Acta Neurochir Suppl 85:101-4. 2003
    ..With the possibility of CT systems becoming more handy and sophisticated, intraoperative CT was introduced in a few neurosurgical Centres with better results in lesion removal and surgical outcome...
  79. ncbi Microsurgical resection of deep-seated lesions using transparent tubular retractor: pediatric case series
    Kyung Il Jo
    Department of Neurosurgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Gangnam Gu, 135 710, Seoul, South Korea
    Childs Nerv Syst 27:1989-94. 2011
    ..To facilitate effective resection of deep-seated brain lesions without causing significant trauma to the overlying cortex, the authors used a transparent plastic tubular retractor to approach these lesions...
  80. ncbi Simultaneous use of functional tractography, neuronavigation-integrated subcortical white matter stimulation and intraoperative magnetic resonance imaging in glioma surgery: technical note
    Jaime Gasco
    Department of Neurosurgery, University of Texas M D Anderson Cancer Center, Houston, TX 77030 4009, USA
    Stereotact Funct Neurosurg 87:395-8. 2009
    ..number of techniques utilized including functional MRI, direct electrophysiological monitoring and functional neuronavigation to maximize and safely resect gliomas...
  81. ncbi Intraoperative low-field magnetic resonance imaging in pediatric neurosurgery
    Christopher Nimsky
    Department of Neurosurgery, University Erlangen Nuremberg, Erlangen, Germany
    Pediatr Neurosurg 38:83-9. 2003
    ..The majority of examinations were carried out in adults. The aim of this study was to summarize our experience of over 5 years of intraoperative MR imaging in pediatric neurosurgery...
  82. ncbi [Posterior spinal instrumentation image guided and assisted by neuronavigation. Experience in 120 cases]
    R Florensa
    Servicio de Neurocirugía Hospital Germans Trias i Pujol Barcelona
    Neurocirugia (Astur) 22:224-34. 2011
    ..The authors present the results of a series of 121 cases of posterior vertebral fixation carried out from Sept 2008 to Sept 2010 using Flouro 2D-TC assisted Vector Vision o Kolibri navigator. ( Brain LAB, Feldkirchen, Germany)...
  83. ncbi The use of noninvasive electromagnetic neuronavigation for slit ventricle syndrome and complex hydrocephalus in a pediatric population
    Simon Clark
    Department of Pediatric Neurosurgery, Royal Liverpool Children s NHS Trust, Walton Centre for Neurology and Neurosurgery, Liverpool, United Kingdom
    J Neurosurg Pediatr 2:430-4. 2008
    The aim of this study was to prospectively evaluate the use of noninvasive electromagnetic neuronavigation in children, in particular its use in complex hydrocephalus and slit ventricle syndrome.
  84. ncbi Effectiveness of neuronavigation in resecting solitary intracerebral contrast-enhancing tumors: a randomized controlled trial
    Peter W A Willems
    Department of Neurosurgery, University Medical Center Utrecht, The Netherlands
    J Neurosurg 104:360-8. 2006
    The goal of this study was to assess the impact of neuronavigation on the cytoreductive treatment of solitary contrast-enhancing intracerebral tumors and outcomes of this treatment in cases in which neuronavigation was preoperatively ..
  85. pmc Correlation of the extent of tumor volume resection and patient survival in surgery of glioblastoma multiforme with high-field intraoperative MRI guidance
    Daniela Kuhnt
    Department of Neurosurgery, University of Marburg, Marburg, Germany
    Neuro Oncol 13:1339-48. 2011
    ..Thus, maximum EOR should be the surgical goal in GBM surgery while preserving neurological function...
  86. ncbi Intraoperative high-field-strength MR imaging: implementation and experience in 200 patients
    Christopher Nimsky
    Department of Neurosurgery, University Erlangen Nurnberg, Schwabachanlage 6, 91054 Erlangen, Germany
    Radiology 233:67-78. 2004
    ..To review the initial clinical experience with intraoperative high-field-strength magnetic resonance (MR) imaging of brain lesions in 200 patients...
  87. ncbi Toward functional neuronavigation: implementation of functional magnetic resonance imaging data in a surgical guidance system for intraoperative identification of motor and language cortices. Technical note and illustrative case
    Geert Jan Rutten
    Department of Neurosurgery, and the Image Sciences Institute, University Medical Center Utrecht, The Netherlands
    Neurosurg Focus 15:E6. 2003
    ..years, surgical navigation systems have become equipped to allow incorporation of data such as functional neuronavigation data...
  88. ncbi Neuronavigation based on CT angiography for surgery of intracranial aneurysms: primary experience with unruptured aneurysms
    R Schmid-Elsaesser
    Department of Neurosurgery, Klinikum Grosshadern, Ludwig Maximilians University, Marchioninistrasse 15, 81377 Munich, Germany
    Minim Invasive Neurosurg 46:269-77. 2003
    ..In the present study we report our experience with neuronavigation based on CTA in 16 patients with unruptured anterior circulation aneurysms for 1) planning craniotomy; 2) ..
  89. ncbi Functional magnetic resonance imaging for neurosurgical planning in neurooncology
    Erik Jan Vlieger
    Department of Radiology, Academic Medical Center, P O Box 22660, 1100 DD Amsterdam, The Netherlands
    Eur Radiol 14:1143-53. 2004
    ..the blood oxygenation level-dependent (BOLD) signal, (3) post-processing the fMRI time course, (4) integration of fMRI results into neuronavigation systems, (5) the accuracy of fMRI and (6) fMRI compared to intra-operative mapping (IOM).
  90. ncbi Language functional magnetic resonance imaging in preoperative assessment of language areas: correlation with direct cortical stimulation
    Franck Emmanuel Roux
    Institut National de la Sante et de la Recherche Medicale, Unité 455, and Federation of Neurosurgery, University Hospitals, Hopital Purpan, F 31059 Toulouse, France
    Neurosurgery 52:1335-45; discussion 1345-7. 2003
    ..The aim of this study was to analyze the usefulness of preoperative language functional magnetic resonance imaging (fMRI), by correlating fMRI data with intraoperative cortical stimulation results for patients with brain tumors...
  91. ncbi Functional neurosurgery in the MRI environment
    A A F De Salles
    Division of Neurosurgery, School of Medicine, University of California Los Angeles, 200 UCLA Medical Plaza Suite 504, Los Angeles, CA 90095 7182, USA
    Minim Invasive Neurosurg 47:284-9. 2004
    ....
  92. ncbi Deep brain stimulation in intraoperative MRI environment - comparison of imaging techniques and electrode fixation methods
    M W Y Lee
    Division of Neurosurgery, University of California Los Angeles School of Medicine, Los Angeles, USA
    Minim Invasive Neurosurg 48:1-6. 2005
    ..Satisfactory microelectrode recording was feasible in low-field 0.2 T and high-field 1.5 T MRI environments. Further studies on performing DBS in real-time intraoperative MRI are warranted...
  93. ncbi A stereotactic method for image-guided transcranial magnetic stimulation validated with fMRI and motor-evoked potentials
    S F W Neggers
    Department of Psychonomics, Helmholtz Institute, Utrecht University, Utrecht, The Netherlands
    Neuroimage 21:1805-17. 2004
    ..The present results demonstrate that NeNa is a reliable method for image-guided TMS coil placement...
  94. ncbi Image fusion for skull base neuronavigation. Technical note
    Ulrich Sure
    Department of Neurosurgery, Philipps University Marburg, Germany
    Neurol Med Chir (Tokyo) 42:458-61; discussion 462. 2002
    ..Color display of the different data sets allows the tumor and the skull base to be distinguished easily. The fused CT data in bone window mode provides useful additional information on the osseous skull base...
  95. ncbi The performance of six pulse oximeters in the environment of neuronavigation
    Alexander M Mathes
    Department of Anesthesiology, Critical Care and Pain Medicine, Saarland University Hospital, Homburg Saar, Germany
    Anesth Analg 107:541-4. 2008
    ..Recently, it was suggested that neuronavigation equipment may interfere with pulse oximeter accuracy...
  96. ncbi An increased precision comparison of TMS-induced motor cortex BOLD fMRI response for image-guided versus function-guided coil placement
    Stewart Denslow
    Department of Radiology, Center for Advanced Imaging Research and Brain Stimulation Laboratories, Medical University of South Carolina, Charleston, South Carolina 29425, USA
    Cogn Behav Neurol 18:119-26. 2005
    ..To examine with high precision the differences between function-guided and image-guided transcranial magnetic stimulation (TMS)...
  97. ncbi Multiplanar MRI-CT fusion neuronavigation-guided serial stereotactic biopsy of human brain tumors: proof of a strong correlation between tumor imaging and histopathology by a new technical approach
    Susanne Antje Kuhn
    Department of Neurosurgery, Medical Center of Friedrich Schiller University, 07747 Jena, Germany
    J Cancer Res Clin Oncol 135:1293-302. 2009
    ....
  98. ncbi Functional neuronavigation combined with intra-operative 3D ultrasound: initial experiences during surgical resections close to eloquent brain areas and future directions in automatic brain shift compensation of preoperative data
    I A Rasmussen
    Norwegian University of Science and Technology, Trondheim, Norway
    Acta Neurochir (Wien) 149:365-78. 2007
    ..fMRI (functional magnetic resonance imaging) and DTI (diffusion tensor imaging) data in an ultrasound-based neuronavigation system...
  99. ncbi Computer-assisted 3D ultrasound-guided neurosurgery: technological contributions, including multimodal registration and advanced display, demonstrating future perspectives
    Toril A Nagelhus Hernes
    SINTEF, Trondheim, Norway
    Int J Med Robot 2:45-59. 2006
    Navigation systems are now frequently being used for guiding surgical procedures. Existing neuronavigation systems suffer from the lack of updated images when tissue changes during surgery as well as from user-friendly displays of all ..
  100. ncbi Brain surface reformatted imaging (BSRI) in surgical planning for resections around eloquent cortex
    David Araujo
    Department of Neurology, Hospital de Clínicas de Ribeirão Preto, Av Bandeirantes 3900, Ribeirao Preto, SP 14048 900, Brazil
    Childs Nerv Syst 22:1122-6. 2006
    ..Using brain surface reformatted imaging (BSRI) of 3-D MR images, we sought to obtain data for surgical planning in patients with lesions around the motor cortex...
  101. ncbi Thalamic cavernous angioma: paraculminar supracerebellar infratentorial transtentorial approach for the safe and complete surgical removal
    N Otani
    Department of Neurosurgery, Zurich University Hospital, Zurich, Switzerland
    Acta Neurochir Suppl 103:29-36. 2008
    ..We describe the advantage of the paraculminar supracerebellar approach to the lesions in the brainstem...

Research Grants26

  1. Precision Targeting of fMRI-Guided TMS Using a Robotic Arm System
    Bruce Luber; Fiscal Year: 2010
    ....
  2. Transcranial Magnetic Stimulation for Treatment of Obsessive Compulsive Disorder
    Antonio Mantovani; Fiscal Year: 2012
    ..protocol to target pre-SMA, in line with recent work suggesting the efficacy of rTMS may be improved through neuronavigation to individual anatomy...
  3. Real-Time Stereotactic Mass Spectrometry Tissue Analysis for Intraoperative Neuro
    NATHALIE YR AGAR; Fiscal Year: 2010
    ..This project aims to integrate a combined mass spectrometry and neuronavigation platform into the clinical environment for in vivo measurement of tumor boundaries...
  4. Clinical Translation of Deformation Compensation for Image-Guided Liver Surgery
    MICHAEL IAN MIGA; Fiscal Year: 2013
    ..It has only just recently found application within the neuronavigation community (although no commercial systems are available yet) and is still under investigation...
  5. Rapid Analysis of Intraoperatively Acquired DTI for Identification of Key White M
    LAUREN JEAN O'DONNELL; Fiscal Year: 2012
    ..take advantage of our new state-of-the-art, high field strength intraoperative 3T MRI system and our research neuronavigation software platform, 3D Slicer...
  6. Correcting for Soft Tissue Deformation in Image-Guided Liver Surgery
    MICHAEL MIGA; Fiscal Year: 2009
    ..It has only just recently found application within the neuronavigation community (although no commercial systems are available yet) and is still under investigation...
  7. Multimodal maps of human imitative behavior
    Marco Iacoboni; Fiscal Year: 2004
    ....
  8. TMS Intervention Development for Auditory Hallucinations
    Ralph Hoffman; Fiscal Year: 2003
    ..The results of these studies will be used to design an intervention algorithm for a full-scale trial of rTMS in a larger group of schizophrenic patients with medication-resistant AHs. ..
  9. MODELING OF BRAIN DEFORMATION DURING SURGERY
    Keith Paulsen; Fiscal Year: 2002
    ..the display of high resolution magnetic resonance (MR) images in the operating room (OR) has revolutionized neuronavigation, tissue motion during surgery compromises the value of preoperative image information for navigational ..
  10. Cortical Distinctions in Visual and Auditory Naming
    SANDRA SERAFINI; Fiscal Year: 2004
    ..abstract_text> ..
  11. Intraoperative 3T MRI Scanner for Minimally Invasive Therapy
    Ferenc Jolesz; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  12. IMAGE GUIDED THERAPY CENTER
    Ferenc Jolesz; Fiscal Year: 2009
    ..abstract_text> ..
  13. Gene methylation in glioma and normal glial cells
    Justin Smith; Fiscal Year: 2005
    ..Furthermore, comparison of methylation patterns may: 1) identify subtype-specific markers to aid in classifying gliomas and 2) provide clues to the cells of origin of gliomas. ..
  14. Post Traumatic Nonconvulsive Epileptiform Activity
    Paul Vespa; Fiscal Year: 2005
    ..The hypothesis and unique approach come at a crucial time of failed clinical trials and address an important new therapeutic target. ..
  15. MRS Detects Metabolic Dysfunction after Brain Injury
    Paul Vespa; Fiscal Year: 2009
    ..The knowledge from the proposed studies will have widespread application to critical care of neurotrauma patients. ..
  16. Continued Development and Maintenance of a Computational Morphometry Toolkit
    Torsten Rohlfing; Fiscal Year: 2010
    ..This project will enhance a proven soft- ware system for imaging-based morphometric studies and make it freely avail- able to the scientific community. ..
  17. PALLIDAL PHYSIOLOGY IN HUMAN AND PRIMATE DYSTONIA
    PHILIP STARR; Fiscal Year: 2005
    ..Development of an animal model in a large nonhuman primate will open the possibility for further detailed investigations of basal ganglia physiology in dystonia, beyond those which are possible during human surgery. ..
  18. LENTIVIRAL DELIVERY OF GDNF AND BCL-2 IN PD MODEL
    Marina Emborg; Fiscal Year: 2003
    ..These studies will serve as the preclinical foundation to determine whether this in vivo method to deliver these potent trophic factor and antiapoptotic genes will be suitable for testing in patients with PD. ..
  19. Myocardial Ischemia and Vasospasm in Aneurysmal SAH
    Michael Horowitz; Fiscal Year: 2008
    ....
  20. Therapeutic Studies of Primary CNS Malignancies-NABTT
    Gene Barnett; Fiscal Year: 2008
    ..abstract_text> ..
  21. Optical imaging of epilepsy in rat and human neocortex
    THEODORE SCHWARTZ; Fiscal Year: 2007
    ..These experiments will set the groundwork for implementing optical recordings in general clinical practice as a novel technique for mapping and predicting human seizures. ..
  22. Effect of vertebral endplate composition on disc health
    Frank Acosta; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  23. Purinergic control of medullary pain modulation
    Nathan Selden; Fiscal Year: 2006
    ..abstract_text> ..
  24. Neurofeedback functional MRI
    Seung Schik Yoo; Fiscal Year: 2006
    ....
  25. Improved Targeting in Minimally Invasive Image-Guided Radio Frequency Ablation
    Neculai Archip; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..