whole body counting

Summary

Summary: Measurement of radioactivity in the entire human body.

Top Publications

  1. ncbi Calcium iodate-another effective blocker of radioiodine uptake by the thyroid gland
    D N Pahuja
    Laboratory Nuclear Medicine Section Isotope Group, B A R C, Tata Memorial Hospital Annexe, Bhabba Atomic Research Center, Parel, Mumbai 400 012, India
    Health Phys 89:92-4. 2005
  2. ncbi Performance characteristics of a commercially available whole body counting phantom measured experimentally and using Monte Carlo simulations
    Gary H Kramer
    Human Monitoring Laboratory, Radiation Protection Bureau, 775 Brookfield Road, Ottawa, Ontario, Canada K1A 1C1
    Health Phys 88:350-6. 2005
  3. ncbi Hiatal hernia in iodine-131 scintigraphy: a potential cause of false-positive midline thoracic uptake
    Mary Freeman
    Department of Nuclear Medicine, Royal North Shore Hospital, Sydney, Australia
    Clin Nucl Med 28:709-10. 2003
  4. ncbi Biodistribution and radiation dosimetry estimates of 1-(2'-deoxy-2'-(18)F-Fluoro-1-beta-D-arabinofuranosyl)-5-bromouracil: PET imaging studies in dogs
    Sridhar Nimmagadda
    Karmanos Cancer Institute, Wayne State University, Detroit, Michigan 48201 2013, USA
    J Nucl Med 46:1916-22. 2005
  5. ncbi Dose assessment for ingestion of a 330 kilobecquerel 60Co hot particle
    D W Whillans
    Health Physics Department, Ontario Power Generation, Whitby, Ontario, Canada L1 N 9E3
    Radiat Prot Dosimetry 127:90-2. 2007
  6. ncbi Whole-body distribution and dosimetry of O-(2-[18F]fluoroethyl)-L-tyrosine
    Dirk Pauleit
    Clinic of Nuclear Medicine, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Eur J Nucl Med Mol Imaging 30:519-24. 2003
  7. ncbi Collimator selection, acquisition speed, and visual assessment of 131I-tositumomab biodistribution in a phantom model
    Hung K Tan
    Division of Nuclear Medicine, Ottawa Hospital, Ottawa, Ontario, Canada
    J Nucl Med Technol 34:224-7. 2006
  8. ncbi A tomographic physical phantom of the newborn child with real-time dosimetry. II. Scaling factors for calculation of mean organ dose in pediatric radiography
    Robert J Staton
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 33:3283-9. 2006
  9. ncbi Biodistribution and radiation dosimetry of 18F-fluoro-A-85380 in healthy volunteers
    Michel Bottlaender
    Department of Medical Research, Division of Life Sciences, Service Hospitalier Frederic Joliot, French Atomic Agency, 4 Place du General Leclerc, F 91406 Orsay, France
    J Nucl Med 44:596-601. 2003
  10. ncbi Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[18F]FMeNER-D2 in non-human primates
    Nicholas Seneca
    Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden
    Nucl Med Commun 26:695-700. 2005

Detail Information

Publications230 found, 100 shown here

  1. ncbi Calcium iodate-another effective blocker of radioiodine uptake by the thyroid gland
    D N Pahuja
    Laboratory Nuclear Medicine Section Isotope Group, B A R C, Tata Memorial Hospital Annexe, Bhabba Atomic Research Center, Parel, Mumbai 400 012, India
    Health Phys 89:92-4. 2005
    ..We have not found any studies that examined the property of Ca(IO3)2 in blocking radioiodine uptake by the thyroid gland and the present study is an attempt in this direction...
  2. ncbi Performance characteristics of a commercially available whole body counting phantom measured experimentally and using Monte Carlo simulations
    Gary H Kramer
    Human Monitoring Laboratory, Radiation Protection Bureau, 775 Brookfield Road, Ottawa, Ontario, Canada K1A 1C1
    Health Phys 88:350-6. 2005
    The performance characteristics of a commercially available whole body counting phantom have been examined experimentally and using Monte Carlo simulations...
  3. ncbi Hiatal hernia in iodine-131 scintigraphy: a potential cause of false-positive midline thoracic uptake
    Mary Freeman
    Department of Nuclear Medicine, Royal North Shore Hospital, Sydney, Australia
    Clin Nucl Med 28:709-10. 2003
    ..Although this appearance could be seen with mediastinal, pulmonary, or prevertebral metastases, hiatal hernia should be considered in the differential diagnosis of uptake in the thoracic midline on I-131 scintigraphy...
  4. ncbi Biodistribution and radiation dosimetry estimates of 1-(2'-deoxy-2'-(18)F-Fluoro-1-beta-D-arabinofuranosyl)-5-bromouracil: PET imaging studies in dogs
    Sridhar Nimmagadda
    Karmanos Cancer Institute, Wayne State University, Detroit, Michigan 48201 2013, USA
    J Nucl Med 46:1916-22. 2005
    ..This study reports on the biodistribution and radiation estimates of 1-(2'-deoxy-2'-(18)F-fluoro-1-beta-d-arabinofuranosyl)-5-bromouracil ((18)F-FBAU), a potential tracer for imaging DNA synthesis...
  5. ncbi Dose assessment for ingestion of a 330 kilobecquerel 60Co hot particle
    D W Whillans
    Health Physics Department, Ontario Power Generation, Whitby, Ontario, Canada L1 N 9E3
    Radiat Prot Dosimetry 127:90-2. 2007
    ..The estimated committed effective dose was 1.4 mSv, and the equivalent dose to the maximally exposed 1 cm2 of skin, 81 mSv...
  6. ncbi Whole-body distribution and dosimetry of O-(2-[18F]fluoroethyl)-L-tyrosine
    Dirk Pauleit
    Clinic of Nuclear Medicine, Heinrich Heine University Dusseldorf, Dusseldorf, Germany
    Eur J Nucl Med Mol Imaging 30:519-24. 2003
    ..5.3% ID/h). The highest absorbed dose was found for the urinary bladder wall. The effective dose according to ICRP 60 was 16.5 micro Sv/MBq for adults, which would lead to an effective dose of 6.1 mSv in a PET study using 370 MBq FET...
  7. ncbi Collimator selection, acquisition speed, and visual assessment of 131I-tositumomab biodistribution in a phantom model
    Hung K Tan
    Division of Nuclear Medicine, Ottawa Hospital, Ottawa, Ontario, Canada
    J Nucl Med Technol 34:224-7. 2006
    ..The effect of scanning speed was also investigated, in an attempt to optimize the acquisition time...
  8. ncbi A tomographic physical phantom of the newborn child with real-time dosimetry. II. Scaling factors for calculation of mean organ dose in pediatric radiography
    Robert J Staton
    Department of Nuclear and Radiological Engineering, University of Florida, Gainesville, Florida 32611 8300, USA
    Med Phys 33:3283-9. 2006
    ..An comprehensive set of SF(POD) values is presented in this article for application in pediatric radiography of newborn patients...
  9. ncbi Biodistribution and radiation dosimetry of 18F-fluoro-A-85380 in healthy volunteers
    Michel Bottlaender
    Department of Medical Research, Division of Life Sciences, Service Hospitalier Frederic Joliot, French Atomic Agency, 4 Place du General Leclerc, F 91406 Orsay, France
    J Nucl Med 44:596-601. 2003
    ..This study reports on the biodistribution and radiation dosimetry of 2-(18)F-Fluoro-3-[2(S)-2-azetidinylmethoxy]pyridine ((18)F-fluoro-A-85380), a promising radioligand for the imaging of central nicotinic acetylcholine receptors (nAChRs)...
  10. ncbi Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[18F]FMeNER-D2 in non-human primates
    Nicholas Seneca
    Karolinska Institutet, Department of Clinical Neuroscience, Karolinska Hospital, Stockholm, Sweden
    Nucl Med Commun 26:695-700. 2005
    ..In this work, we quantified the biodistribution over time and radiation exposure to multiple organs with (S,S)-[F]FMeNER-D2...
  11. ncbi Biodistribution and radiation dosimetry of the dopamine D2 ligand 11C-raclopride determined from human whole-body PET
    Mark Slifstein
    Department of Psychiatry, Columbia University, New York, New York 10032, USA
    J Nucl Med 47:313-9. 2006
    ..Whole-body radiation dosimetry of 11C-raclopride was performed in healthy human volunteers...
  12. ncbi Biodistribution and radiation dosimetry of [123I]ADAM in healthy human subjects: preliminary results
    Tomi A Kauppinen
    Division of Nuclear Medicine, Helsinki University Central Hospital, P O Box 340, 00029 Helsinki, Finland
    Eur J Nucl Med Mol Imaging 30:132-6. 2003
    ..2.10(-2) mSv/MBq. The results suggest that [(123)I]ADAM is of potential value as a tracer for single-photon emission tomography imaging of serotonin receptors in humans, with acceptable dosimetry and high brain uptake...
  13. ncbi Biodistribution and radiation dosimetry of [11C]raclopride in healthy volunteers
    Maria Joao Ribeiro
    Service Hospitalier Frederic Joliot, Departement de Recherche Medicale, Direction des Sciences du Vivant, Commissariat a l Energie Atomique, Orsay Cedex, France
    Eur J Nucl Med Mol Imaging 32:952-8. 2005
    ..This study reports on the whole-body biodistribution and radiation dosimetry of [11C]raclopride, a dopamine D2 receptor antagonist...
  14. ncbi Dosimetry and toxicity of Quadramet for bone marrow ablation in multiple myeloma and other haematological malignancies
    Marissa L Bartlett
    Department of Nuclear Medicine, Royal Brisbane Hospital, Herston, Queensland, Q4209, Australia
    Eur J Nucl Med Mol Imaging 29:1470-7. 2002
    ..In addition, myelosuppression was achieved without evidence of myelofibrosis. The residual dose rate to marrow fell to a level acceptable for stem cell re-infusion by 2 weeks after administration...
  15. ncbi Dosimetric analysis of the carousel setup for the exposure of rats at 1.62 GHz
    Frank Schönborn
    Laboratory for Integrated Systems at the Swiss Federal Institute of Technology, Zurich, Switzerland
    Bioelectromagnetics 25:16-26. 2004
    ..e., 0.8-3 ghz...
  16. ncbi Biodistribution and radiation dosimetry of [N-methyl-11C]mirtazapine, an antidepressant affecting adrenoceptors
    Katalin Marthi
    PET Center, Aarhus University Hospital, Nørrebrogade 44, Aarhus C 8000, Denmark
    Appl Radiat Isot 59:175-9. 2003
    ..2 x 10(-2) mGy/MBq), and gallbladder wall (1.1 x 10(-2) mGy/MBq). The effective dose was estimated to be 6.8 x 10(-3) mSv/MBq, which is similar to that produced by several radioligands used routinely for neuroimaging...
  17. ncbi Repeated injections of 131I-rituximab show patient-specific stable biodistribution and tissue kinetics
    Cristian Antonescu
    Service of Nuclear Medicine, University Hospital of Lausanne, Lausanne, Switzerland
    Eur J Nucl Med Mol Imaging 32:943-51. 2005
    ..The aim of this study was to evaluate the evolution of the pharmacokinetics of repeated 131I-rituximab injections during treatment with unlabelled rituximab in patients with non-Hodgkin's lymphoma (NHL)...
  18. ncbi Measurement of the residual radioactivity induced in the front foil of a target assembly in a modern medical cyclotron
    R G O'Donnell
    Molecular Imaging Institute M2i, Blackrock Clinic, Blackrock, Co Dublin, Ireland
    Appl Radiat Isot 60:539-42. 2004
    ....
  19. ncbi Biokinetic models for the behaviour of carbon-14 from labelled compounds in the human body: can a single generic model be justified?
    David M Taylor
    Chemistry Department, Cardiff University, Cardiff, CF10 3TB, UK
    Radiat Prot Dosimetry 108:187-202. 2004
    ..However, a comparison of the biokinetic information indicates that the ICRP default model would not be reliable for the interpretation of bioassay data...
  20. ncbi Technologist radiation exposure in routine clinical practice with 18F-FDG PET
    Benjamin Guillet
    Unité de Radiopharmacie, Service Central de Medecine Nucleaire, CHU Timone, Marseille, France
    J Nucl Med Technol 33:175-9. 2005
    ....
  21. ncbi Doses to nuclear technicians in a dedicated PET/CT centre utilising 18F fluorodeoxyglucose (FDG)
    T Seierstad
    Buskerud University College, Faculty of Health, Konggate 51, N 3019 Drammen, Norway
    Radiat Prot Dosimetry 123:246-9. 2007
    ..Even a major increase in the number of patients will not result in individual doses near the ICRP dose limit...
  22. ncbi Safety, biodistribution, and dosimetry of 99mTc-HYNIC-annexin V, a novel human recombinant annexin V for human application
    Gerrit J Kemerink
    Department of Nuclear Medicine, University Hospital Maastricht, Maastricht, The Netherlands
    J Nucl Med 44:947-52. 2003
    ..The present study on humans was performed to investigate the safety of (99m)Tc-HYNIC-annexin V and to quantify the biodistribution and radiation dose...
  23. ncbi A generic biokinetic model for predicting the behaviour of the lanthanide elements in the human body
    D M Taylor
    Department of Chemistry, Cardiff University, PO Box 912, Cardiff CF10 3TB, Wales, UK
    Radiat Prot Dosimetry 105:193-8. 2003
    ..This report describes the use of the available biokinetic data for humans and animals to derive the parameters for each of the elements...
  24. ncbi A Monte Carlo-based method to estimate radiation dose from spiral CT: from phantom testing to patient-specific models
    G Jarry
    McGill University, Medical Physics Unit, Montreal General Hospital, Montreal, Canada
    Phys Med Biol 48:2645-63. 2003
    ..Results of initial testing are promising and application to patient models was shown to be feasible...
  25. ncbi Whole-body radiation dosimetry of 2-[18F]Fluoro-A-85380 in human PET imaging studies
    Sebastian L Obrzut
    Department of Radiology, Division of Nuclear Medicine, University of California San Diego, La Jolla, CA 92093, USA
    Nucl Med Biol 32:869-74. 2005
    ..184 rad/mCi) and the kidneys (0.0470 mGy/MBq, 0.174 rad/mCi). The mean effective dose equivalent is estimated to be 0.0278 mSv/MBq (0.103 rem/mCi), indicating that radiation dosimetry associated with 2-[18F]FA is within acceptable limits...
  26. ncbi Differentiated thyroid cancer: comparison of therapeutic iodine 131 biological elimination after discontinuation of levothyroxine versus administration of recombinant human thyrotropin
    Dimitris Papadimitriou
    Department of Nuclear Medicine, White Cross General Hospital, Piraeus, Greece
    Ann Nucl Med 20:63-7. 2006
    ....
  27. ncbi Safety, pharmacokinetic and dosimetry evaluation of the proposed thrombus imaging agent 99mTc-DI-DD-3B6/22-80B3 Fab'
    David J Macfarlane
    Department of Nuclear Medicine, Royal Brisbane and Women s Hospital, Australia
    Eur J Nucl Med Mol Imaging 33:648-56. 2006
    ..The purpose of this study was to evaluate the safety, pharmacokinetics and dosimetry of four increasing doses of (99m)Tc-DI-80B3 Fab' in healthy volunteers...
  28. ncbi Americium in the beagle dog: biokinetic and dosimetric model
    A Luciani
    ENEA Radiation Protection Institute, Via dei Colli, 16 40136 Bologna, Italy
    Health Phys 90:459-70. 2006
    ..For the skeletal tissues, the dose to the cortical endosteum by far exceeds the dose to the trabecular endosteum and the red marrow. The model provides the basis for statistical survival analyses and risk estimates...
  29. ncbi Determination of dose coefficients and urinary excretion function for inhalation of carbon-14-labelled benzene
    A Krins
    VKTA Nuclear Engineering and Analytics Rossendorf Inc, Postfach 510119, D 01314 Dresden, Germany
    Radiat Prot Dosimetry 104:139-52. 2003
    ..The uncertainty of the dose coefficients is estimated to be about 50% for the exposure range covered. A 14-day interval for the incorporation monitoring by urine activity counting seems to be reasonable...
  30. ncbi Biodistribution and dosimetry study of 123I-rh-annexin V in mice and humans
    C M M Lahorte
    Department of Radiopharmacy, Faculty of Pharmaceutical Sciences, Gent University, Belgium
    Nucl Med Commun 24:871-80. 2003
    ..The average effective dose of 123I-rh-annexin V was estimated to be 0.02 mSv.MBq-1. The amount of 123I-rh-annexin V required for in vivo imaging, results in an acceptable effective dose to the patient...
  31. ncbi Age-dependent protection quantities for external neutron irradiation
    D P Chou
    Institute of Nuclear Energy Research P O Box 3 10, Lungtan 325, Taiwan, ROC
    Radiat Prot Dosimetry 104:5-16. 2003
    ..The age-dependent equivalent doses behave similarly to the effective doses, with some exceptions caused by the influence of the organ position...
  32. ncbi Effective dose equivalent for point gamma sources located 10 cm near the body
    X George Xu
    Nuclear Engineering and Engineering Physics, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Health Phys 91:108-18. 2006
    ..Finally, this paper provides recommendations on how to apply the EPRI EDE methodology...
  33. ncbi 131I effective half-life (Teff) for patients with thyroid cancer
    J Willegaignon
    Radiological Protection Service, Instituto de Pesquisas Energéticas e Nucleares, Cidade Universitaria, Sao Paulo, Brazil
    Health Phys 91:119-22. 2006
    ..41 +/- 0.02 h; this information may be used in guidelines on the management of patients in thyroid cancer therapy and for general radioprotection practice...
  34. ncbi Preclinical studies on [11C]TMSX for mapping adenosine A2A receptors by positron emission tomography
    Kiichi Ishiwata
    Positron Medical Center, Tokyo Metropolitan Institute of Gerontology, Japan
    Ann Nucl Med 17:205-11. 2003
    ..We have concluded that [11C]TMSX is suitable for mapping adenosine A2A receptors in the human brain by PET...
  35. ncbi Evaluation of the potential absorbed doses from patients based on whole-body 131I clearance in thyroid cancer therapy
    J Willegaignon
    Radiological Protection Service, Instituto de Pesquisas Energéticas e Nucleares, Cidade Universitaria, Sao Paulo, Brazil
    Health Phys 91:123-7. 2006
    ..0 +/- 0.7 to 8.4 +/- 1.1 mSv at 1 m and 1.2 +/- 0.4 to 3.2 +/- 0.4 mSv at 2 m. The data reported here are important to radioprotection policy and to add to and improve on the guidelines reported in U.S. NRC Regulatory Guide 8.39...
  36. ncbi Management of the helpless patient after radioiodine ablation therapy - are we being too strict?
    Catherine E Williams
    Directorate of Medical Physics and Clinical Engineering, Singleton Hospital, Swansea, UK
    Nucl Med Commun 26:925-8. 2005
    ..Published data suggest that nursing staff may receive a total effective dose of 3400 microSv when dealing with such a patient for one 8 h shift per day for 7 days post-treatment...
  37. ncbi Japanese adult male voxel phantom constructed on the basis of CT images
    K Sato
    Tokai Research Establishment, Japan Atomic Energy Research Institute, 2 4 Shirakata Shirane, Tokai mura, Naka gun, Ibaraki ken 319 1195, Japan
    Radiat Prot Dosimetry 123:337-44. 2007
    ..In consequence, it was suggested that the mass, shape and thickness of organs are important factors for the determination of self-AFs...
  38. ncbi Dosimetry of the dopamine transporter radioligand 18F-FPCIT in human subjects
    William Robeson
    Center for Neurosciences, North Shore University Hospital, Manhasset, New York, USA
    J Nucl Med 44:961-6. 2003
    ..The goal was to determine a limiting dose consistent with accepted guidelines for use in clinical studies and to compare the radiation burden with other agents such as (123)I-FPCIT, (18)F-fluorodopa, and (18)F-FDG...
  39. ncbi A biokinetic model for carbon dioxide and bicarbonate
    R W Leggett
    Oak Ridge National Laboratory, 1060 Commerce Park, Oak Ridge, Tennessee 37831, USA
    Radiat Prot Dosimetry 108:203-13. 2004
    ..Model predictions of the time-dependent distribution and retention of carbon differ considerably from those of models recommended by the International Commission on Radiological Protection...
  40. ncbi Biodistribution and radiation dosimetry of the A1 adenosine receptor ligand 18F-CPFPX determined from human whole-body PET
    Hans Herzog
    Institute of Neuroscience and Biophysics Medicine, Forschungszentrum Juelich GmbH, D 52425, Juelich, Germany
    Eur J Nucl Med Mol Imaging 35:1499-506. 2008
    ..The purpose of this study was to determine the biodistribution and the radiation dose of (18)F-CPFPX by whole-body scans in humans...
  41. ncbi 5-[123I]Iodo-A-85380: assessment of pharmacological safety, radiation dosimetry and SPECT imaging of brain nicotinic receptors in healthy human subjects
    Masashi Ueda
    Department of Patho Functional Bioanalysis, Graduate School of Pharmaceutical Sciences, Kyoto University, Japan
    Ann Nucl Med 18:337-44. 2004
    ..These results suggest that [123I]5IA is a promising ligand for imaging nAChRs in humans, with an acceptable dosimetry and pharmacological safety at the dose required for adequate SPECT imaging...
  42. ncbi Narrow beam neutron dosimetry
    M Sutton Ferenci
    Emory University, School of Medicine, Department of Radiation Oncology, 1365 Clifton Road, NE, Atlanta, GA 30322, USA
    Radiat Prot Dosimetry 110:813-7. 2004
    ..The calculations were carried out using the Monte Carlo transport code MCNPX 2.5c...
  43. ncbi Specific absorbed fractions for internal photon emitters calculated for a tomographic model of a pregnant woman
    C Y Shi
    Nuclear Engineering and Engineering Physics Programs, Rensselaer Polytechnic Institute, Troy, NY 12180, USA
    Health Phys 87:507-11. 2004
    ..The main reasons for the differences are due to the variation of mass, geometry, and organ distances, and they demonstrate the influence of more realistic body models on dose calculations...
  44. ncbi Biodistribution and radiation dosimetry of the serotonin transporter ligand 11C-DASB determined from human whole-body PET
    Jian Qiang Lu
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892 0135, USA
    J Nucl Med 45:1555-9. 2004
    ..The goal of this study was to provide dosimetry estimates for 11C-DASB based on human whole-body PET...
  45. ncbi Quantitation of small-animal (124)I activity distributions using a clinical PET/CT scanner
    Dinko E González Trotter
    Functional Imaging Laboratory, General Electric Global Research, Niskayuna, NY 12309, USA
    J Nucl Med 45:1237-44. 2004
    ..The recovery coefficients found from the phantom data were applied to in vivo (124)I anti-HER2/neu C6.5 diabody PET data and compared with necropsy biodistribution data from the same tumor-bearing immunodeficient mouse...
  46. ncbi Radiation dose estimates in humans for (11)C-acetate whole-body PET
    Marc A Seltzer
    Department of Molecular and Medical Pharmacology, Ahmanson Biological Imaging Center, University of California at Los Angeles School of Medicine, Los Angeles, California, USA
    J Nucl Med 45:1233-6. 2004
    ..Dynamic whole-body (11)C-acetate PET was therefore performed on 6 healthy human volunteers. Measured dose estimates for all target organs were compared with the existing ORISE values...
  47. ncbi Radiolabeling, biodistribution, and dosimetry of (123)I-mAb 14C5: a new mAb for radioimmunodetection of tumor growth and metastasis in vivo
    Christophe M M Lahorte
    Department of Radiopharmacy, Faculty of Pharmaceutical Sciences, Gent University, Gent, Belgium
    J Nucl Med 45:1065-73. 2004
    ..This study reports on the in vitro evaluation, biodistribution, and dosimetry of (123)I-labeled monoclonal antibody (mAb) 14C5, a new antibody-based agent proposed for radioimmunodetection of tumor growth and metastasis in vivo...
  48. pmc Whole-body biodistribution and radiation dosimetry estimates for the PET dopamine transporter probe 18F-FECNT in non-human primates
    Dnyanesh N Tipre
    Molecular Imaging Branch, National Institute of Mental Health, National Institutes of Health, Bldg 1 Rm B3 10, 1 Center Drive, Bethesda, MD 20892 0135, USA
    Nucl Med Commun 25:737-42. 2004
    ..The aim of the current study was to quantify the distribution of radioactivity in three rhesus monkeys after the injection of approximately 185 MBq (5 mCi) of 18F-FECNT...
  49. ncbi A comparison of (111)In-DOTATOC and (111)In-DOTATATE: biodistribution and dosimetry in the same patients with metastatic neuroendocrine tumours
    F Forrer
    Institute of Nuclear Medicine, University Hospital, Petersgraben 4, 4031, Basel, Switzerland
    Eur J Nucl Med Mol Imaging 31:1257-62. 2004
    ....
  50. ncbi Myelotoxicity and RBE of 211At-conjugated monoclonal antibodies compared with 99mTc-conjugated monoclonal antibodies and 60Co irradiation in nude mice
    Jörgen Elgqvist
    Department of Radiation Physics, The Sahlgrenska Academy at Goteborg University, Goteborg, Sweden
    J Nucl Med 46:464-71. 2005
    ....
  51. ncbi Biodistribution and excretion of radioactivity after the administration of 166Ho-chitosan complex (DW-166HC) into the prostate of rat
    Seung Kyoo Seong
    Pharmacology and Toxicology Lab, Central Research Laboratories, Dong Wha Pharmaceutical Co, Ltd, Anyang, South Korea
    Eur J Nucl Med Mol Imaging 32:910-7. 2005
    ..The objective of this study was to determine the fate of the 166Ho-chitosan complex (DW-166HC) in rats by examining its absorption, distribution and excretion after administration into the prostate...
  52. ncbi Biodistribution and radiation dosimetry of [11C]DASB in baboons
    Marie Jose Belanger
    Department of Psychiatry, Columbia University College of Physicians and Surgeons, New York, NY 10032, USA
    Nucl Med Biol 31:1097-102. 2004
    ..We report on the biodistribution and dosimetry of [(11)C]DASB in the baboon as this species may be a more reliable surrogate for human dosimetry...
  53. ncbi Whole-body biodistribution and radiation dosimetry of the human cannabinoid type-1 receptor ligand 18F-MK-9470 in healthy subjects
    Koen Van Laere
    Division of Nuclear Medicine, University Hospital and K U Leuven, Leuven, Belgium
    J Nucl Med 49:439-45. 2008
    ..We have used whole-body PET/CT to characterize the biodistribution and dosimetry of a novel high-affinity, subtype-selective radioligand, (18)F-MK-9470, in healthy male and female subjects...
  54. ncbi Radiation-absorbed dose from 201Tl-thallous chloride
    Stephen R Thomas
    Department of Radiology, University of Cincinnati, College of Medicine, Cincinnati, OH 45267 0579, USA
    J Nucl Med 46:502-8. 2005
    ....
  55. ncbi Absorption of zinc from wheat products fortified with iron and either zinc sulfate or zinc oxide
    Daniel Lopez de Romaña
    Program in International Nutrition, Department of Nutrition, University of California, Davis, USA
    Am J Clin Nutr 78:279-83. 2003
    ..Several chemical forms of zinc have been proposed for food fortification, but information is needed on their absorption from common cereals having varied phytate content...
  56. ncbi Abnormalities of body composition in peritoneal dialysis patients
    Graham Woodrow
    Renal Unit, Leeds General Infirmary, England, United Kingdom
    Perit Dial Int 24:169-75. 2004
    ..We investigated abnormalities of nutrition and hydration in PD patients compared with healthy controls by measurement of total body potassium (TBK) and body water compartments...
  57. pmc The UF family of reference hybrid phantoms for computational radiation dosimetry
    Choonsik Lee
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institute of Health, Bethesda, MD 20852, USA
    Phys Med Biol 55:339-63. 2010
    ....
  58. ncbi Composition of gestational weight gain impacts maternal fat retention and infant birth weight
    Nancy F Butte
    U S Department of Agriculture Agriculture Research Service, Children s Nutrition Research Center, 1100 Bates Street, Houston, TX 77030, USA
    Am J Obstet Gynecol 189:1423-32. 2003
    ..The purpose of this study was to evaluate how changes in gestational weight and body composition affect infant birth weight and maternal fat retention after delivery in underweight, normal-weight and overweight women...
  59. ncbi Copper deficiency reduces iron absorption and biological half-life in male rats
    Philip G Reeves
    U S Department of Agriculture, ARS, Grand Forks Human Nutrition Research Center, Grand Forks, ND 58203, USA
    J Nutr 134:1953-7. 2004
    ..01) than in CuA rats. These findings suggest that Fe deficiency anemia in CuD male rats is caused at least in part by reductions in Fe absorption and retention...
  60. ncbi Differences in skeletal and muscle mass with aging in black and white women
    J F Aloia
    Department of Medicine, Winthrop University Hospital, Mineola 11501, New York, USA
    Am J Physiol Endocrinol Metab 278:E1153-7. 2000
    Previous cross-sectional studies using delayed gamma neutron activation analysis and whole body counting suggested that the relationship of total body calcium (TBCa) to total body potassium (TBK) (muscle mass, body cell mass) remained ..
  61. ncbi Hydrothermal treatment and malting of barley improved zinc absorption but not calcium absorption in humans
    K Fredlund
    Department of Food Science, Chalmers University of Technology, Box 5401, SE 402 29 Goteborg, Sweden
    Eur J Clin Nutr 57:1507-13. 2003
    ..To study whether hydrothermal treatment or malting of barley (cv. Blenheim) improves zinc and calcium absorption in humans...
  62. ncbi (111)Indium-transferrin for localization and quantification of gastrointestinal protein loss
    Jane Angel Simonsen
    Department of Nuclear Medicine, Odense University Hospital, Odense C, Denmark
    Scand J Gastroenterol 44:1191-7. 2009
    ..To evaluate the indium-111 ((111)In)-transferrin method as a means of localization and quantification of gastrointestinal protein loss...
  63. ncbi Older men and women efficiently absorb vitamin B-12 from milk and fortified bread
    R M Russell
    Jean Mayer U S Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, Massachusetts 02111, USA
    J Nutr 131:291-3. 2001
    ..0 microCi) (51)Cr as a stool marker. Whole body counting was performed 30 min after ingestion of the radioactive dose and at 7 and 14 d after dosing...
  64. ncbi Metallothionein induction is not involved in cadmium accumulation in the duodenum of mice and rats fed diets containing high-cadmium rice or sunflower kernels and a marginal supply of zinc, iron, and calcium
    Philip G Reeves
    U S Department of Agriculture, ARS, Grand Forks Human Nutrition Research Center, Grand Forks, ND 58203, USA
    J Nutr 135:99-108. 2005
    ..In addition, they support the hypothesis that marginal deficiencies of Fe, Zn, and Ca, commonly found in certain human populations subsisting on rice-based diets, play an important role in increasing the risk of dietary Cd exposure...
  65. ncbi Anthropomorphic models for checking the calibration of whole-body counters and activation analysis systems
    D K Bewley
    MRC Cyclotron Unit, Hammersmith Hospital, London, UK
    Phys Med Biol 33:805-13. 1988
    ..For K, differences did not exceed 17% but are still often greater than the expected uncertainty. The greatest errors usually occurred with the smallest manikin...
  66. ncbi The overview of internal exposure monitoring in Lithuania
    B Griciene
    Radiation Protection Centre, Kalvariju 153, Vilnius LT 08221, Lithuania
    Radiat Prot Dosimetry 127:398-401. 2007
    ..Radiation workers are assessed for internal exposures by direct methods--whole body counting or organ counting by gamma spectrometry at the Radiation Protection Centre and Ignalina Nuclear Power Plant ..
  67. ncbi Cellular potassium depletion predisposes to hypokalaemia after oral sodium phosphate
    A G Hill
    University Department of Surgery, Auckland Hospital, New Zealand
    Aust N Z J Surg 68:856-8. 1998
    ..The authors of the present study tested the hypothesis that patients with cellular depletion of potassium are at significant risk for hypokalaemia with oral sodium phosphate bowel preparation...
  68. pmc Antibody mass escalation study in patients with castration-resistant prostate cancer using 111In-J591: lesion detectability and dosimetric projections for 90Y radioimmunotherapy
    Neeta Pandit-Taskar
    Nuclear Medicine Service, Department of Radiology, Memorial Sloan Kettering Cancer Center, New York, New York 10021, USA
    J Nucl Med 49:1066-74. 2008
    ..An analysis was performed to assess lesion detectability by (111)In-J591 gamma-camera imaging compared with standard imaging methods and the effect of increasing antibody mass on lesion detectability, biodistribution, and dosimetry...
  69. ncbi Excretion of depleted uranium by Gulf War veterans
    R E Toohey
    Oak Ridge Institute for Science and Education, Oak Ridge, TN 37830, USA
    Radiat Prot Dosimetry 105:171-4. 2003
    ..Thus, human data available to date do not provide any basis for determining the effects of particle surface area, composition and solubility, and biological processes such as encapsulation, on the excretion rate...
  70. ncbi Influence of sodium selenite on 203Hg absorption, distribution, and elimination in male mice exposed to methyl203Hg
    A W Glynn
    Swedish National Food Administration, Uppsala
    Biol Trace Elem Res 39:91-107. 1993
    ..The results indicate that selenium treatment of MeHg-exposed mice may have a positive effect on the health of the animals by decreasing the total body burden of MeHg...
  71. ncbi Soybean ferritin: implications for iron status of vegetarians
    Bo Lonnerdal
    Department of Nutrition, University of California, Davis, CA, USA
    Am J Clin Nutr 89:1680S-1685S. 2009
    ..In conclusion, iron is well absorbed from ferritin and may represent a means of biofortification of staple foods such as soybeans...
  72. ncbi Age-related decline in body cell mass in elderly men and women, determined by a noninvasive nuclear technique: effects of physical activity and dietary potassium intake
    M Dittmar
    Institute of Anthropology, Department of Biology, J Gutenberg University, Mainz, Germany
    Am J Hum Biol 13:204-11. 2001
    ..In women, PAL was the only significant predictor of BCM, explaining 23% of the variance. The study supports the hypothesis that the level of physical activity is associated with the decline of BCM in the elderly...
  73. ncbi Nonheme-iron absorption, fecal ferritin excretion, and blood indexes of iron status in women consuming controlled lactoovovegetarian diets for 8 wk
    J R Hunt
    US Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, ND 58202 9034, USA
    Am J Clin Nutr 69:944-52. 1999
    ..The characteristics of vegetarian diets suggest that these diets would have lower dietary iron bioavailability than nonvegetarian diets, but there is no evidence of iron deficiency in vegetarians...
  74. ncbi The interference of medical radionuclides with occupational in vivo gamma spectrometry
    R Kol
    Nuclear Research Center Negev NRCN, Health Physics Department, PO Box 9001, Beer Sheva 84190, Israel
    Health Phys 84:756-63. 2003
    ..The monitoring of internal exposures involves gamma spectrometry of the whole body (whole body counting) and measurements of excreta samples...
  75. ncbi Effect of low zinc diet on (65)Zn turnover in non-insulin dependent diabetic mice
    Z Kechrid
    Department of Biochemistry, Faculty of Sciences, University of Annaba BP 12, El Hadjar, Annaba 23000, Algeria
    Diabetes Metab 27:580-3. 2001
    ..To investigate the effect of low-Zn diet on (65)Zn turnover and content in non-insulin dependent diabetes (NIDDM)...
  76. ncbi Controlled substitution of soy protein for meat protein: effects on calcium retention, bone, and cardiovascular health indices in postmenopausal women
    Zamzam K Roughead
    United States Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, North Dakota 58202 9034, USA
    J Clin Endocrinol Metab 90:181-9. 2005
    ..Substitution of 25 g high isoflavone soy protein for meat, in the presence of typical calcium intakes, did not improve or impair calcium retention or indicators of bone and cardiovascular health in postmenopausal women...
  77. ncbi Retrospective determination of the contamination in the HML's counting chambers
    Gary H Kramer
    Human Monitoring Laboratory, Radiation Surveillance and Health Assessment Division, Radiation Protection Bureau, 775 Brookfield Road, PL6302D1, Ottawa, Ontario, Canada
    Health Phys 95:346-51. 2008
    ..combined with experimental measurements to estimate the level of contamination in the steel of the HML's whole body counting chamber. A 24-h empty chamber background count showed the presence of 137Cs and 60Co...
  78. ncbi The german thorotrast study: recent results and assessment of risks
    G van Kaick
    Deutsches Krebsforschungszentrum, E0100, D 69120 Heidelberg, Germany
    Radiat Res 152:S64-71. 1999
    ..For hematopoietic malignancies, the cumulative risk was calculated to be about 7 per 10(4) person Sv (radiation weighting factor = 20). This risk estimate is lower by a factor of 10 compared to the results of the Life Span Study...
  79. pmc Transport of particles of colloidal gold within and from rat lung after local deposition by alveolar microinjection
    G Patrick
    Medical Research Council Radiobiology Unit, Chilton, Oxfordshire, UK
    Environ Health Perspect 97:47-51. 1992
    ..At the later times after microinjection, much of the gold colloid was associated with thickened pleura and adjoining septae...
  80. pmc Considerations in assigning dose based on uncertainties from in vivo counting
    G H Kramer
    National Calibration Reference Centre for In Vivo Monitoring, Human Monitoring Laboratory, Ottawa, Ontario, Canada
    Environ Health Perspect 105:1393-5. 1997
    ..If the measurement is done correctly, biases can usually be kept below 20%. However, if the measurement is made with a collimator or if the detector is in contact with the subject's neck, biases exceeding 200% can be obtained...
  81. ncbi Dietary manganese intake and type of lipid do not affect clinical or neuropsychological measures in healthy young women
    John W Finley
    US Department of Agriculture, Agricultural Research Service, Grand Forks Human Nutrition Research Center, Grand Forks, ND, USA
    J Nutr 133:2849-56. 2003
    ..Thus, dietary intakes of Mn from 0.8 to 20 mg for 8 wk likely do not result in Mn deficiency or toxicity signs in healthy adults...
  82. ncbi Mobilisation of cadmium by meso- and racemic-2,3-dimercaptosuccinic acid (DMSA) in rats
    M Blanusa
    Institute for Medical Research and Occupational Health, Zagreb, Croatia
    Pharmacol Toxicol 87:179-81. 2000
    ..3% to 3.5%). In conclusion, these results show modest reduction of cadmium in the body by two isoforms of DMSA with rac-DMSA being slightly more efficient than meso-DMSA...
  83. ncbi Sensitivity of a low energy Ge detector system for in vivo monitoring in the framework of ICRP 78 applications
    M A Lopez
    CIEMAT Internal Dosimetry Group, Avda Complutense 22, 28040 Madrid, Spain
    Radiat Prot Dosimetry 105:477-82. 2003
    ..The whole body counting (WBC) faculty at CIEMAT uses a low-energy Ge detector system with different available counting geometries ..
  84. ncbi The relationship between energy expenditure and lean tissue in monozygotic twins discordant for spinal cord injury
    William A Bauman
    Department of Veterans Affairs Rehabilitation Research and Development Center of Excellence, Spinal Cord Damage Research Center, Bronx, NY 10468, USA
    J Rehabil Res Dev 41:1-8. 2004
    ..In summary, twins with SCI had lower energy expenditure than their able-bodied co-twins. Regardless of paralysis, direct linear relationships existed between energy expenditure and measures of lean mass...
  85. ncbi Gastrointestinal absorption of neptunium and curium in humans
    D S Popplewell
    National Radiological Protection Board, Chilton, Didcot, Oxfordshire
    Health Phys 60:797-805. 1991
    ....
  86. ncbi Comparative deterministic effects of inhaled, insoluble alpha- and beta-particle-emitting radionuclides in dogs
    B A Muggenburg
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87185, USA
    Radiat Res 152:S23-6. 1999
    ..The greater tissue penetration of the beta-particle emissions from the cerium resulted in more uniform dose distribution over the lung and the atria of the heart than from the alpha-particle emissions from plutonium...
  87. ncbi A simplified method for determination of radioactive iron in whole-blood samples
    K Bukhave
    Centre for Advanced Food Studies, Department of Biochemistry and Nutrition, Technical University of Denmark, Lyngby
    J Trace Elem Med Biol 15:56-8. 2001
    ....
  88. ncbi Validation of different bioimpedance analyzers for predicting cell mass against whole-body counting of potassium (40K) as a reference method
    Manuela Dittmar
    Institute of Anthropology, Department of Biology, Gutenberg University, 55099 Mainz, Germany
    Am J Hum Biol 16:697-703. 2004
    ..This does not hold true for females. Because both BIA devices overestimate BCM, the newly developed device-specific equations which reduce bias and limits of agreement should be applied...
  89. ncbi The second international in-vivo monitoring intercomparison program for whole body counting facilities by Canadian and United States agencies
    G H Kramer
    Human Monitoring Laboratory, Radiation Protection Bureau, Ottawa, Ontario, Canada
    Health Phys 80:214-24. 2001
    ..States Department of Energy collaborated to offer a second international in vivo intercomparison program to whole body counting facilities in 1996...
  90. ncbi Low serum vitamin B12 levels in chronic high-flux haemodialysis patients
    S M Chandna
    Department of Renal Medicine, Lister Hospital, Stevenage, UK
    Nephron 75:259-63. 1997
    ..This study demonstrates that low serum B12 levels occur in high-flux haemodialysis patients and that losses during dialysis and dietary deficiency may be contributing factors...
  91. ncbi Assessment of total body potassium in healthy Italian men
    A De Lorenzo
    Human Nutrition Unit, Via Montpellier 1, University of Rome Tor Vergata, 00173 Rome, Italy
    Ann Hum Biol 31:381-8. 2004
    ..Whole-body (40)K counting is a valuable tool for assessing cellular changes in body composition with ageing...
  92. ncbi Usefulness of the simultaneous bioassay analysis method used for an intake estimation of a radionuclide
    Jong Il Lee
    Korea Atomic Energy Research Institute, PO Box 105, Yuseong Gu, Daejeon, Republic of Korea
    Radiat Prot Dosimetry 127:430-4. 2007
    ....
  93. ncbi Weight loss in postmenopausal obesity: no adverse alterations in body composition and protein metabolism
    D Gallagher
    Department of Medicine, Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University, New York, New York 10025, USA
    Am J Physiol Endocrinol Metab 279:E124-31. 2000
    ..and appendicular lean soft tissue (LST) by dual-energy X-ray absorptiometry; body cell mass (BCM) by (40)K whole body counting; total body water (TBW) by tritium dilution; skeletal muscle (SM) by whole body MRI; and fasting whole body ..
  94. ncbi Influence of zinc on the status of hepatic trace elements and biokinetics of 65Zn in ethanol treated rats
    D Dhawan
    Department of Biophysics, Panjab University, Chandigarh 160 014, India
    Indian J Exp Biol 43:259-63. 2005
    b>Whole body counting studies of 65Zn indicated that the Tb1 (the faster component) was significantly decreased while the slower component (Tb2) was increased significantly following ethanol treatment...
  95. ncbi Repletion of copper-deficient rats with dietary copper restores duodenal hephaestin protein and iron absorption
    Philip G Reeves
    USDA, ARS, Grand Forks Human Nutrition Research Center, 2420 Second Avenue North, Grand Forks, ND 58203, USA
    Exp Biol Med (Maywood) 230:320-5. 2005
    ..These findings suggest a strong association between duodenal Hp abundance and Fe absorption in the CuD rat, and that reduced Fe absorption is an important factor in the cause of anemia...
  96. ncbi Comparative stochastic effects of inhaled alpha- and beta-particle-emitting radionuclides in beagle dogs
    F F Hahn
    Lovelace Respiratory Research Institute, Albuquerque, New Mexico 87185, USA
    Radiat Res 152:S19-22. 1999
    ..In addition, inhaled beta-particle emitters can also induce cancers in lung-associated lymph nodes and heart at these larger absorbed radiation doses...
  97. ncbi A whole body counting facility in a remote Enewetak Island setting
    Thomas R Bell
    US Department of Energy, Office of Health Studies, Germantown, MD 20874 1290, USA
    Health Phys 83:S22-6. 2002
    ..The laboratory facility was completed in May 2001. The laboratory incorporates both a permanent whole body counting system to assess internal exposures to 137Cs, and clean living space for people providing 24-h void urine ..
  98. ncbi Incidence and consequences of total body potassium depletion in chronic hemodialysis patients
    George M Dolson
    Renal Section, Department of Medicine, Veterans Affairs Medical Center, 2002 Holcombe Blvd, Houston, TX 77030, USA
    Front Biosci 8:a126-32. 2003
    ..METHODOLOGY AND OUTCOME MEASURE: TBK by whole-body counting of 40K, dialysis potassium losses, and patient demographic characteristics were determined. Survival was evaluated retrospectively after seven years of follow-up...
  99. ncbi Dietary copper deficiency reduces iron absorption and duodenal enterocyte hephaestin protein in male and female rats
    Philip G Reeves
    U S Department of Agriculture, ARS, Grand Forks Human Nutrition Research Center, Grand Forks, ND 58203, USA
    J Nutr 135:92-8. 2005
    ..Liver Fe was much higher (<0.001) overall in females than males. The data suggest that Cu deficiency reduces Fe absorption in rats through reduced expression of duodenal Hp protein...
  100. ncbi Whole-body skeletal muscle mass: development and validation of total-body potassium prediction models
    ZiMian Wang
    Obesity Research Center, St Luke s Roosevelt Hospital, Columbia University College of Physicians and Surgeons, New York, USA
    Am J Clin Nutr 77:76-82. 2003
    ..There are now > 30 whole-body counters worldwide that have large cross-sectional and longitudinal TBK databases...
  101. ncbi An approach for the efficiency calibration of whole body counters
    L Venturini
    Instituto de Pesquisas Energéticas e Nucleares, Departamento de Radioproteção Ocupacional, Pinheiros, Sao Paulo, Brazil
    Health Phys 81:580-4. 2001
    ..The relative geometry dependence was found to be less than 9% for the "Reference Man" and "Reference 10-y-old Child" phantoms...

Research Grants36

  1. Exploring Specific Metabolic Rates of Major Cell Categories in Adiposity-Diverse
    ZiMian Wang; Fiscal Year: 2010
    ..The potential outcome of this study can be expected to improve our understanding of the inherent relations between REE and cellular level body composition and establishing energy requirement of obese adults. ..
  2. BLOCKING NEGATIVE SIGNALS TO NK CELLS TO TREAT LEUKEMIA
    Michael Bennett; Fiscal Year: 2003
    ..of growing tumors and for labeling leukemia cells that are infused so that survival can be determined by whole body counting. Aim 3...
  3. GA68 TC-99M BIFUNCTIONAL MOABS FOR PET AND SPECT IMAGING
    David Goodwin; Fiscal Year: 1990
    ..The methodology involves immunizing mice with specially designed antigens, screening by whole body counting of mice with radioactive antigens, organ distribution and gamma camera imaging in tumor mice and PET and ..
  4. Exploring Growth Energy Expenditure in Normal-Weight and Overweight Children
    ZiMian Wang; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  5. Virtual Patients for Computing Radiation Doses
    Xie Xu; Fiscal Year: 2007
    ..These two cores then support four parallel clinical projects. [unreadable] [unreadable] [unreadable]..
  6. 4D Visible Human Modeling for Radiation Dosimetry
    Xie George Xu; Fiscal Year: 2010
    ..4).To establish an internet-based information-sharing resource on virtual-human motion simulation and radiation dosimetry. ..
  7. Radiopharmaceutical Dosimetry Symposium
    Michael Stabin; Fiscal Year: 2002
    ..abstract_text> ..
  8. Biological Predictors of Response to Antidepressants
    Ramin V Parsey; Fiscal Year: 2010
    ..Our overall goal is to reduce the trial and error associated with finding an effective antidepressant by using data from pre-treatment quantification of 5-HT1A receptors and 5-HTT to guide antidepressant treatment selection. ..
  9. Mammalian Lactoferrin Receptors: Structure and Function
    Bo Lonnerdal; Fiscal Year: 2007
    ..Overall, our understanding of the physiological significance of Lf and its receptor will be increased. ..
  10. Imaging of Serotonin Transporters in Depression
    RAMIN PARSEY; Fiscal Year: 2005
    ..These goals will be met by a combination of didactic I course work and supervision. ..
  11. Realistic Phantom Series for OLINDA/EXM Version 2
    Michael Stabin; Fiscal Year: 2007
    ..unreadable] [unreadable]..
  12. New Methods for Improved Image-based Dosimetry
    Michael Stabin; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  13. Metabolic Effects of Differential Organ Growth Rates
    Dympna Gallagher; Fiscal Year: 2007
    ..The proposed studies will provide new insights into growth-related changes in REE and between-individual REE differences, notably those observed between race groups. ..
  14. The 8th International Symposium on In-Vivo Body Composition Studies
    Dympna Gallagher; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  15. FLT PET to Plan the Best Therapy for Lung Cancer
    Hubert Vesselle; Fiscal Year: 2008
    ..At the conclusion of this study, the insight gained in the response of stage III NSCLCs will allow clinicians to plan the best therapy for these patients. [unreadable] [unreadable]..
  16. Lung Cancer Prognosis: FLT PET and DNA Hypermethylation
    Hubert Vesselle; Fiscal Year: 2009
    ..This prognostic information will permit individualization and optimization of therapy for the 41,000 early stage NSCLC patients undergoing surgical resection each year in the United States. ..
  17. Thiazolidinediones as Thyroid Cancer Therapy
    BRYAN HAUGEN; Fiscal Year: 2009
    ....
  18. Two-dimensional MR Spectroscopic Characterization of HE
    Michael Thomas; Fiscal Year: 2006
    ..Minimal spectral overlap leading to less ambiguous assignment and better quantitation of glutamate/glutamine, GABA, myo-inositol, threonine, glucose, taurine and glutathione, will be a major outcome of this work. ..
  19. HEPATIC ENCEPHALOPATHY--NEUROPSYCHOLOGY & NEUROCHEMISTRY
    Michael Thomas; Fiscal Year: 2001
    ..This enhanced understanding of pathophysiology will improve our ability to diagnose and treat this condition, resulting in improved patient outcomes. ..
  20. Periodontal Disease and Rheumatoid Arthritis
    Michael McCracken; Fiscal Year: 2005
    ..Furthermore, it is hypothesized that among patients with rheumatoid arthritis, an association exists between the rate of progression of inflammatory arthritis and the progression of periodontal disease. ..
  21. Effect of Diabetes on Bone Integration of Implants
    Michael McCracken; Fiscal Year: 2002
    ..This knowledge may lead to bioengineered materials which will modify and improve bone healing response in diabetic patients who receive implants. ..
  22. VITAMIN D SUPPLEMENTATION IN POSTMENOPAUSAL WOMEN
    John Aloia; Fiscal Year: 2002
    ..If this randomized clinical trial demonstrates a positive effect on prevention of bone loss, a large scale multi-centered trial with fracture prevention as an endpoint will have merit. ..
  23. Pretargeting mouse tumor with anti-PSMA antibody-MORF
    Guozheng Liu; Fiscal Year: 2005
    ..Based on our experiences in this pretargeting strategy, we are confident that these investigations on the pretargeting imaging of prostate cancer models with MORFs will be successful. ..
  24. ROLE OF RETINOIDS AND RECEPTORS IN THYROTROPE FUNCTION
    BRYAN HAUGEN; Fiscal Year: 2004
    ....
  25. Thick scintillation detector with continuous positioning & DOI capability for PET
    Suleman Surti; Fiscal Year: 2008
    ..Hence, thick continuous detectors have the potential to significantly impact the clinical imaging situation and the resultant patient treatment. [unreadable] [unreadable] [unreadable]..
  26. MRI Derived Organ & Tissue Mass Changes With Weight Loss
    Dympna Gallagher; Fiscal Year: 2003
    ..The proposed studies promise to answer important body composition related questions regarding the composition of weight loss at the organ/tissue level. ..
  27. THE BIOLOGY OF LUNG CANCER-- FDG AND FLUOROTHYMIDINE PET
    Hubert Vesselle; Fiscal Year: 2004
    ..By performing a biologic grading of resectable NSCLC with FDG PET, we will predict which patients will have a worse outcome. This information will allow individualized therapy. ..
  28. {F18}paclitaxel: an in vivo marker for MDR in tumors
    Karen Kurdziel; Fiscal Year: 2004
    ..Microarray results will be used in combination with those described above to provide preliminary evidence for FPAC's use as an in vivo marker for MDR caused by Pgp. ..
  29. Micro Computerized Tomography Imaging System
    PETER CONTI; Fiscal Year: 2004
    ....
  30. Multimodality in vivo Molecular Imaging for Prostate PDT
    Baowei Fei; Fiscal Year: 2007
    ..The proposed imaging strategy has great potential to enhance public health by improving diagnosis and therapy of cancer. ..
  31. High Resolution Ultrasound Resource for Molecular Imaging Center
    PETER CONTI; Fiscal Year: 2007
    ..The discoveries and advancements made by these investigators will ultimately have a direct positive impact on public health. [unreadable] [unreadable] [unreadable]..
  32. Quantitative Assessment of Murine Tumors with MicroPET.
    Craig Abbey; Fiscal Year: 2004
    ..The third study proposes a study in which a well-known therapeutic agent, tamoxifen, is introduced. The data from this study will allow evaluation of the magnitude and statistical significance of a therapeutic effect. ..
  33. Non-Invasive Localization of Vulnerable Plaques
    Cynthia McCollough; Fiscal Year: 2009
    ....
  34. SMALL ANIMAL PET SCANNER FOR CANCER APPLICATIONS
    PETER CONTI; Fiscal Year: 2001
    ..USC has the leadership, scientific investigators, equipment and facilities necessary to provide an environment in which the potential benefits of a small animal PET scanner can be fully realized. ..
  35. Dose and image quality in adult and pediatric CT
    Walter Huda; Fiscal Year: 2006
    ..Determine the choice of kVp/mAs and PR/mAs that minimize patient doses with no loss of diagnostic performance. 3. Help the Radiology community to balance the confliciting requirements of image quality and patient doses in clinical CT. ..