radiometry

Summary

Summary: The measurement of radiation by photography, as in x-ray film and film badge, by Geiger-Mueller tube, and by SCINTILLATION COUNTING.

Top Publications

  1. ncbi On the dosimetric behaviour of photon dose calculation algorithms in the presence of simple geometric heterogeneities: comparison with Monte Carlo calculations
    Antonella Fogliata
    Oncology Institute of Southern Switzerland, Medical Physics Unit, Bellinzona, Switzerland
    Phys Med Biol 52:1363-85. 2007
  2. ncbi IMRT commissioning: multiple institution planning and dosimetry comparisons, a report from AAPM Task Group 119
    Gary A Ezzell
    Department of Radiation Oncology, Mayo Clinic Scottsdale, 5777 East Mayo Boulevard, MCSB Concourse, Phoenix, Arizona 89054, USA
    Med Phys 36:5359-73. 2009
  3. ncbi Analysis of radiation-induced liver disease using the Lyman NTCP model
    Laura A Dawson
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 53:810-21. 2002
  4. ncbi Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997
    Dale L Preston
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 160:381-407. 2003
  5. pmc Tangential beam IMRT versus tangential beam 3D-CRT of the chest wall in postmastectomy breast cancer patients: a dosimetric comparison
    Volker Rudat
    Department of Radiation Oncology, Saad Specialist Hospital, Saudi Arabia
    Radiat Oncol 6:26. 2011
  6. ncbi Testing of the analytical anisotropic algorithm for photon dose calculation
    Ann Van Esch
    7Sigma, QA team in Radiotherapy Physics, Belgium and Clinique Ste Elisabeth, Namur, Belgium
    Med Phys 33:4130-48. 2006
  7. pmc Intensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and clinical implications
    Leire Arbea
    Department of Oncology, Clinica Universidad de Navarra, Pamplona, Spain
    Radiat Oncol 5:17. 2010
  8. ncbi Calculation and prediction of the effect of respiratory motion on whole breast radiation therapy dose distributions
    Junsheng Cao
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA
    Med Dosim 34:126-32. 2009
  9. ncbi Secondary neutron doses for several beam configurations for proton therapy
    Dongho Shin
    Proton Therapy Center, National Cancer Center, Goyang, Korea
    Int J Radiat Oncol Biol Phys 74:260-5. 2009
  10. ncbi RapidArc treatment verification in 3D using polymer gel dosimetry and Monte Carlo simulation
    Sofie Ceberg
    Department of Medical Radiation Physics, Lund University, Skane University Hospital, Malmo, Sweden
    Phys Med Biol 55:4885-98. 2010

Detail Information

Publications342 found, 100 shown here

  1. ncbi On the dosimetric behaviour of photon dose calculation algorithms in the presence of simple geometric heterogeneities: comparison with Monte Carlo calculations
    Antonella Fogliata
    Oncology Institute of Southern Switzerland, Medical Physics Unit, Bellinzona, Switzerland
    Phys Med Biol 52:1363-85. 2007
    ..035 g cm(-3)), enhanced for the most energetic beam. For denser, and more clinical, densities a better agreement among the sophisticated algorithms with respect to MC was observed...
  2. ncbi IMRT commissioning: multiple institution planning and dosimetry comparisons, a report from AAPM Task Group 119
    Gary A Ezzell
    Department of Radiation Oncology, Mayo Clinic Scottsdale, 5777 East Mayo Boulevard, MCSB Concourse, Phoenix, Arizona 89054, USA
    Med Phys 36:5359-73. 2009
    ..Other facilities can use the test protocol and results as a basis for comparison to this group. Locally derived confidence limits that substantially exceed these baseline values may indicate the need for improved IMRT commissioning...
  3. ncbi Analysis of radiation-induced liver disease using the Lyman NTCP model
    Laura A Dawson
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI 48109 0010, USA
    Int J Radiat Oncol Biol Phys 53:810-21. 2002
    ..To describe the dose-volume tolerance for radiation-induced liver disease (RILD) using the Lyman-Kutcher-Burman (LKB) normal tissue complication probability (NTCP) model...
  4. ncbi Studies of mortality of atomic bomb survivors. Report 13: Solid cancer and noncancer disease mortality: 1950-1997
    Dale L Preston
    Department of Statistics, Radiation Effects Research Foundation, Hiroshima, Japan
    Radiat Res 160:381-407. 2003
    ..Lifetime risk summaries are used to examine uncertainties of the LSS noncancer disease findings...
  5. pmc Tangential beam IMRT versus tangential beam 3D-CRT of the chest wall in postmastectomy breast cancer patients: a dosimetric comparison
    Volker Rudat
    Department of Radiation Oncology, Saad Specialist Hospital, Saudi Arabia
    Radiat Oncol 6:26. 2011
    ..planned tangential beam intensity modulated radiotherapy (IMRT) compared to standard wedged tangential beam three-dimensionally planned conformal radiotherapy (3D-CRT) of the chest wall in unselected postmastectomy breast cancer patients..
  6. ncbi Testing of the analytical anisotropic algorithm for photon dose calculation
    Ann Van Esch
    7Sigma, QA team in Radiotherapy Physics, Belgium and Clinique Ste Elisabeth, Namur, Belgium
    Med Phys 33:4130-48. 2006
    ..Particular progress was made with respect to the penumbra and low dose regions. In heterogeneous materials, improvements are substantial and more pronounced for high (18 MV) than for low (6 MV) energies...
  7. pmc Intensity-modulated radiation therapy (IMRT) vs. 3D conformal radiotherapy (3DCRT) in locally advanced rectal cancer (LARC): dosimetric comparison and clinical implications
    Leire Arbea
    Department of Oncology, Clinica Universidad de Navarra, Pamplona, Spain
    Radiat Oncol 5:17. 2010
    ....
  8. ncbi Calculation and prediction of the effect of respiratory motion on whole breast radiation therapy dose distributions
    Junsheng Cao
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, IL, USA
    Med Dosim 34:126-32. 2009
    ..With this model, the dosimetric coverage difference introduced by respiratory motion could be evaluated during patient CT simulation. An appropriate treatment method can be chosen after the simulation...
  9. ncbi Secondary neutron doses for several beam configurations for proton therapy
    Dongho Shin
    Proton Therapy Center, National Cancer Center, Goyang, Korea
    Int J Radiat Oncol Biol Phys 74:260-5. 2009
    ..To compare possible neutron doses produced in scanning and scattering modes, with the latter assessed using a newly built passive-scattering proton beam line...
  10. ncbi RapidArc treatment verification in 3D using polymer gel dosimetry and Monte Carlo simulation
    Sofie Ceberg
    Department of Medical Radiation Physics, Lund University, Skane University Hospital, Malmo, Sweden
    Phys Med Biol 55:4885-98. 2010
    ..Using MC simulations and gel measurements, this verification study successfully demonstrated that the RapidArc plan was both accurately calculated and delivered as planned...
  11. ncbi Relation between lineal energy distribution and relative biological effectiveness for photon beams according to the microdosimetric kinetic model
    Hiroyuki Okamoto
    Department of Energy Sciences, Tokyo Institute of Technology, Kanagawa, Japan
    J Radiat Res 52:75-81. 2011
    ..As a result, the RBE of the photon beams (y(D): 2~5 keV/µm) in arbitrary conditions can be derived by the measurements only or the calculations only of the dose-mean lineal energy...
  12. ncbi EPR dosimetry with tooth enamel: A review
    Paola Fattibene
    Istituto Superiore di Sanita, Department of Technology and Health, Viale Regina Elena, Rome, Italy
    Appl Radiat Isot 68:2033-116. 2010
    ..Results of and problems encountered in international intercomparisons and epidemiological studies are also dealt with. In the final section the future of EPR dosimetry with tooth enamel is analyzed...
  13. pmc Intensity modulated proton therapy treatment planning using single-field optimization: the impact of monitor unit constraints on plan quality
    X R Zhu
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Med Phys 37:1210-9. 2010
    ..To investigate the effect of monitor unit (MU) constraints on the dose distribution created by intensity modulated proton therapy (IMPT) treatment planning using single-field optimization (SFO)...
  14. ncbi Treatment planning for a scanned carbon beam with a modified microdosimetric kinetic model
    Taku Inaniwa
    Medical Physics Research Group, Research Center for Charged Particle Therapy, National Institute of Radiological Sciences, 4 9 1 Anagawa, Inage Ku, Chiba 263 8555, Japan
    Phys Med Biol 55:6721-37. 2010
    ..Good agreement between the two curves proves that the proposed method is a candidate for calculating the biological effects in treatment planning for ion irradiation...
  15. ncbi Feasibility of CBCT-based dose calculation: comparative analysis of HU adjustment techniques
    Irina Fotina
    Department of Radiotherapy, Medical University Vienna AKH Wien, Austria
    Radiother Oncol 104:249-56. 2012
    ..The aim of this work was to compare the accuracy of different HU adjustments for CBCT-based dose calculation...
  16. ncbi Development and evaluation of an efficient approach to volumetric arc therapy planning
    Karl Bzdusek
    Philips Healthcare, Fitchburg, Wisconsin 53711, USA
    Med Phys 36:2328-39. 2009
    ..Optimization and final dose calculation took between 5 and 35 min depending on plan complexity...
  17. ncbi 3D-Conformal versus intensity-modulated postoperative radiotherapy of vaginal vault: A dosimetric comparison
    Savino Cilla
    Department of Oncology, John Paul II Center for High Technology Research and Education in Biomedical Sciences, Catholic University, Campobasso, Italy
    Med Dosim 35:135-42. 2010
    ..A significant dosimetric advantage of IMRT over 3D-RT in the adjuvant treatment of vaginal vault alone in terms of treatment conformity and rectum and bladder sparing is shown...
  18. pmc Comparison of therapeutic dosimetric data from passively scattered proton and photon craniospinal irradiations for medulloblastoma
    Rebecca M Howell
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Radiat Oncol 7:116. 2012
    ....
  19. ncbi 3D Dosimetric verification of volumetric-modulated arc therapy by portal dosimetry
    Anton Mans
    Department of Radiation Oncology, The Netherlands Cancer Institute Antoni van Leeuwenhoek Hospital, Amsterdam, The Netherlands
    Radiother Oncol 94:181-7. 2010
    ..To demonstrate the feasibility of back-projection portal dosimetry for accurate 3D dosimetric verification of volumetric-modulated arc therapy (VMAT), pre-treatment as well as in vivo...
  20. ncbi EGSnrc Monte Carlo calculated dosimetry parameters for 192Ir and 169Yb brachytherapy sources
    R E P Taylor
    Carleton Laboratory for Radiotherapy Physics, Ottawa Carleton Institute of Physics, Carleton University Campus Ottawa, Ontario KIS 5B6, Canada
    Med Phys 35:4933-44. 2008
    ..physics.carleton.ca/clrp/seed_database/)...
  21. pmc Bone marrow dosimetry in peptide receptor radionuclide therapy with [177Lu-DOTA(0),Tyr(3)]octreotate
    Flavio Forrer
    Department of Nuclear Medicine, Erasmus MC Rotterdam, Dr Molewaterplein 40, NL 3015 GD, Rotterdam, The Netherlands
    Eur J Nucl Med Mol Imaging 36:1138-46. 2009
    ..Also, we evaluated the absorbed cross-dose from the source organs (liver, spleen, kidneys and blood), tumours and the so-called "remainder of the body" to the bone marrow...
  22. ncbi Effects of pulsed, spatially fractionated, microscopic synchrotron X-ray beams on normal and tumoral brain tissue
    E Brauer-Krisch
    European Synchrotron Radiation Facility, B P 220, 38043 Grenoble, France
    Mutat Res 704:160-6. 2010
    ..Details on experimental and theoretical dosimetry of microbeams, core issues and possible therapeutic applications of MRT are presented...
  23. ncbi A new homogeneity index based on statistical analysis of the dose-volume histogram
    Myonggeun Yoon
    Research Institute and Hospital, National Cancer Center, Goyang, Korea
    J Appl Clin Med Phys 8:9-17. 2007
    ..A guideline for evaluating the dose homogeneity of treatment plans based on the S-index and its relation to equivalent uniform dose is discussed...
  24. ncbi Dosimetry of yttrium-labelled radiopharmaceuticals for internal therapy: 86Y or 90Y imaging?
    Stephan Walrand
    Center of Nuclear Medicine, Universite Catholique de Louvain, Brussels, Belgium
    Eur J Nucl Med Mol Imaging 38:S57-68. 2011
    ..The potential imaging capabilities with the radioisotopes (87)Y and (88)Y are also considered. Additional studies required to assess specific unaddressed issues are also identified...
  25. ncbi Radiobiological characterization of proton beam at the National Cancer Center in Korea
    Hye Jung Baek
    Radiation Medicine Branch, National Cancer Center, Goyang, Korea
    J Radiat Res 49:509-15. 2008
    ..1 for protons of the majority of centers. Due to the recommendation of a generic RBE of 1.1 for protons, a representative RBE value of 1.1 was assigned for clinical application for proton beams at the NCCPTC...
  26. ncbi Tolerances for the accuracy of photon beam dose calculations of treatment planning systems
    J Venselaar
    Department of Radiotherapy, Dr. B. Verbeeten Institute, P.O. Box 90120, 5000 LA, Tilburg, The Netherlands
    Radiother Oncol 60:191-201. 2001
    ..The new set of tolerances and the quantity confidence limit have proven to be useful tools for the acceptance of photon beam dose calculation algorithms of treatment planning systems...
  27. ncbi Dosimetry for treatment with radiolabelled somatostatin analogues. A review
    M Cremonesi
    Medical Physics, European Institute of Oncology, Milan, Italy
    Q J Nucl Med Mol Imaging 54:37-51. 2010
    ..Special focus is given on recent improvements and indications for critical organ protection that light up challenging perspectives for PRRT...
  28. pmc Accuracy of out-of-field dose calculations by a commercial treatment planning system
    Rebecca M Howell
    The University of Texas Health Science Center Houston, Graduate School of Biomedical Sciences, Houston, TX 77030, USA
    Phys Med Biol 55:6999-7008. 2010
    ..Studies that require accurate out-of-field dose should use other dose reconstruction methods, such as direct measurements or Monte Carlo calculations...
  29. ncbi Secondary neutron dose during proton therapy using spot scanning
    Uwe Schneider
    Division of Medical Physics, Department of Radiation Oncology and Nuclear Medicine, City Hospital Triemli, CH 8063 Zurich, Switzerland
    Int J Radiat Oncol Biol Phys 53:244-51. 2002
    ..In this study, we estimated the neutron dose in patients from a spot scanning beam line by performing measurements and Monte Carlo simulations...
  30. ncbi Dosimetric validation of Acuros XB with Monte Carlo methods for photon dose calculations
    K Bush
    Department of Medical Physics, British Columbia Cancer Agency Vancouver Island Center, Victoria, British Columbia V8R 6V5, Canada
    Med Phys 38:2208-21. 2011
    ....
  31. ncbi Optimizing breast cancer treatment efficacy with intensity-modulated radiotherapy
    Frank A Vicini
    Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, MI 48073, USA
    Int J Radiat Oncol Biol Phys 54:1336-44. 2002
    ..To present our clinical experience using intensity-modulated radiation therapy (IMRT) to improve dose uniformity and treatment efficacy in patients with early-stage breast cancer treated with breast-conserving therapy...
  32. ncbi Influence of CT contrast agents on dose calculations in a 3D treatment planning system
    U Ramm
    Universitatsklinikum, ZRad, Klinik f Strahlentherapie, Frankfurt Main, Germany
    Phys Med Biol 46:2631-5. 2001
    ..4% and 5.4% for 6 MV and 25 MV photon beams, respectively. However, since the CA concentration and its expansion are rather low the effect on dose calculation in treatment planning is negligible...
  33. pmc Patient study of in vivo verification of beam delivery and range, using positron emission tomography and computed tomography imaging after proton therapy
    Katia Parodi
    Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA
    Int J Radiat Oncol Biol Phys 68:920-34. 2007
    ..To investigate the feasibility and value of positron emission tomography and computed tomography (PET/CT) for treatment verification after proton radiotherapy...
  34. ncbi Combined approach of hematological biomarkers and plasma protein SAA for improvement of radiation dose assessment triage in biodosimetry applications
    Natalia I Ossetrova
    AFRRI, SRD, 8901 Wisconsin Avenue, Bethesda, MD 20889 5603, USA
    Health Phys 98:204-8. 2010
    ....
  35. pmc The use of gamma-H2AX as a biodosimeter for total-body radiation exposure in non-human primates
    Christophe E Redon
    Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, USA
    PLoS ONE 5:e15544. 2010
    ..However, knowledge of individual exposures is essential for early triage during radiological incidents to provide optimum possible life-sparing medical procedures to each person...
  36. ncbi Entrance and exit dose measurements with semiconductors and thermoluminescent dosemeters: a comparison of methods and in vivo results
    T Loncol
    Cliniques Universitaires Saint Luc, Service de radiothérapie oncologique, Universite Catholique de Louvain, Bruxelles, Belgique
    Radiother Oncol 41:179-87. 1996
    ....
  37. ncbi The influence of different IMRT techniques on the peripheral dose: a comparison between sMLM-IMRT and helical tomotherapy
    Tilo Wiezorek
    Department of Radiotherapy, University Hospital Jena, Jena, Germany
    Strahlenther Onkol 185:696-702. 2009
    ..To investigate how segmented multileaf modulation-(sMLM-)based intensity-modulated radiotherapy (IMRT) and dynamic helical tomotherapy (ToTh) affect the peripheral dose (PD) outside the treated region...
  38. ncbi The management of respiratory motion in radiation oncology report of AAPM Task Group 76
    Paul J Keall
    Virginia Commonwealth University, USA
    Med Phys 33:3874-900. 2006
    ..Respiratory motion management is also appropriate when the procedure will increase normal tissue sparing. Respiratory motion management involves further resources, education and the development of and adherence to QA procedures...
  39. ncbi Comparison of dose calculation algorithms for treatment planning in external photon beam therapy for clinical situations
    Tommy Knöös
    Radiation Physics, Lund University Hospital, S 221 85 Lund, Sweden
    Phys Med Biol 51:5785-807. 2006
    ..The more sophisticated models in the type b group exhibit changes in both absorbed dose and its distribution which are congruent with the simulations performed by Monte Carlo-based virtual accelerator...
  40. ncbi The risk of radiation-induced cerebrovascular disease in Chernobyl emergency workers
    V K Ivanov
    Medical Radiological Research Center of Russian Academy of Medical Sciences, Obninsk, Russia
    Health Phys 90:199-207. 2006
    ..002, with 95% CI = (-0.004; -0.001). The radiation risks in this large-scale cohort study were not adjusted for recognized risk factors such as excessive weight, hypercholesterolemia, smoking, alcohol consumption, and others...
  41. ncbi The effect of different lung densities on the accuracy of various radiotherapy dose calculation methods: implications for tumour coverage
    Lasse Rye Aarup
    Department of Radiation Oncology, Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark
    Radiother Oncol 91:405-14. 2009
    ..To evaluate against Monte-Carlo the performance of various dose calculations algorithms regarding lung tumour coverage in stereotactic body radiotherapy (SBRT) conditions...
  42. pmc The risk of developing a second cancer after receiving craniospinal proton irradiation
    Wayne D Newhauser
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX, 77030, USA
    Phys Med Biol 54:2277-91. 2009
    ..Simulations revealed that both passively scattered and scanned-beam proton therapies confer significantly lower risks of second cancers than 6 MV conventional and intensity-modulated photon therapies...
  43. ncbi Evaluation of the gamma dose distribution comparison method
    Daniel A Low
    Department of Radiation Oncology, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Med Phys 30:2455-64. 2003
    ..For clinical cases, the calculation time is typically 5 minutes for a 1 x 1 mm2 interpolated resolution on an 800 MHz Pentium 4 for a 14.1 x 15.2 cm2 radiographic film...
  44. ncbi Optimizing the accuracy of a helical diode array dosimeter: a comprehensive calibration methodology coupled with a novel virtual inclinometer
    Jakub Kozelka
    Sun Nuclear Corp, Melbourne, FL 32940, USA
    Med Phys 38:5021-32. 2011
    ..This work introduces enhancements to the measurement accuracy of a 3D dosimeter comprised of a helical plane of diodes in a volumetric phantom...
  45. ncbi Dosimetric evaluation of a novel polymer gel dosimeter for proton therapy
    O A Zeidan
    M D Anderson Cancer Center Orlando, Orlando, Florida 32806, USA
    Med Phys 37:2145-52. 2010
    ..The aim of this study is to evaluate the dosimetric performance of a newly developed proton-sensitive polymer gel formulation for proton therapy dosimetry...
  46. pmc Adapting the γ-H2AX assay for automated processing in human lymphocytes. 1. Technological aspects
    Helen C Turner
    Center for Radiological Research, Columbia University Medical Center, New York, New York 10032, USA
    Radiat Res 175:282-90. 2011
    ..This study demonstrates for the first time the optimization and use of our robotically based biodosimetry workstation to successfully quantify γ-H2AX total fluorescence in irradiated peripheral lymphocytes...
  47. ncbi Review of retrospective dosimetry techniques for external ionising radiation exposures
    E A Ainsbury
    Centre for Radiation, Health Protection Agency, Chemical and Environmental Hazards, Chilton, Didcot, Oxfordshire OX11 0RQ, UK
    Radiat Prot Dosimetry 147:573-92. 2011
    ..Whilst no single technique fulfils the criteria of an ideal dosemeter, an integrated approach using multiple techniques tailored to the exposure scenario can cover most requirements...
  48. ncbi A dosimetric planning study comparing intensity-modulated radiotherapy with four-field conformal pelvic radiotherapy for the definitive treatment of cervical carcinoma
    J Forrest
    Department of Radiation Oncology, Odette Cancer Centre, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
    Clin Oncol (R Coll Radiol) 24:e63-70. 2012
    ..The magnitude of potential dose sparing of OAR is unknown when planning target volumes are defined to include potential organ motion and microscopic disease extent...
  49. pmc Plasma miRNA as biomarkers for assessment of total-body radiation exposure dosimetry
    Wanchang Cui
    Department of Environmental Health Sciences, Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States of America
    PLoS ONE 6:e22988. 2011
    ..Thus, plasma-based biomarkers can be used to assess radiation exposure after mass-casualty incidents, and it may provide a valuable tool in developing and implementing effective countermeasures...
  50. ncbi Influence of dose calculation algorithms on the predicted dose distribution and NTCP values for NSCLC patients
    Tine B Nielsen
    Laboratory of Radiation Physics, Odense University Hospital, University of Southern Denmark, DK 5000 Odense, Denmark
    Med Phys 38:2412-8. 2011
    ..To investigate differences in calculated doses and normal tissue complication probability (NTCP) values between different dose algorithms...
  51. pmc Low early ototoxicity rates for pediatric medulloblastoma patients treated with proton radiotherapy
    Benjamin J Moeller
    Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA
    Radiat Oncol 6:58. 2011
    ..Compared to photons, proton radiotherapy reduces radiation dose to the cochlea for these patients. Here we examine whether this dosimetric advantage leads to a clinical benefit in audiometric outcomes...
  52. ncbi RapidArc radiotherapy planning for prostate cancer: single-arc and double-arc techniques vs. intensity-modulated radiotherapy
    Henry C K Sze
    Department of Clinical Oncology, Pamela Youde Nethersole Eastern Hospital, Hong Kong, China
    Med Dosim 37:87-91. 2012
    ..SA achieved the greatest treatment efficiency but with the highest rectal dose, which was nonetheless within tolerable limits. For busy units with high patient throughput, SA could be an acceptable option...
  53. ncbi Pretreatment patient-specific IMRT quality assurance: a correlation study between gamma index and patient clinical dose volume histogram
    M Stasi
    Department of Medical Physics, Institute for Cancer Research and Treatment, Candiolo, Italy
    Med Phys 39:7626-34. 2012
    ....
  54. ncbi Dosimetric comparison of RapidArc with fixed gantry intensity-modulated radiotherapy treatment for multiple liver metastases radiotherapy
    Yong Yin
    School of Information Science and Engineering of Shandong University, Shandong Province, China
    Med Dosim 36:448-54. 2011
    ..This, in combination with fewer monitor units and short delivery time, can lead to clinically significant advances for the treatment of multiple liver metastases...
  55. ncbi Dosimetric evaluation of a three-phase adaptive radiotherapy for nasopharyngeal carcinoma using helical tomotherapy
    Winky Wing Ki Fung
    Department of Radiotherapy, Hong Kong Sanatorium and Hospital, Hong Kong
    Med Dosim 37:92-7. 2012
    ..046, respectively). The 3-phase radiotherapy protocol showed improved dosimetric results to the critical structures while keeping satisfactory target dose coverage, which demonstrated the advantages of ART in helical tomotherapy of NPC...
  56. ncbi Dose painting by contours versus dose painting by numbers for stage II/III lung cancer: practical implications of using a broad or sharp brush
    Gert Meijer
    Radiotherapy Department, Catharina Hospital Eindhoven, The Netherlands
    Radiother Oncol 100:396-401. 2011
    ..We compared two approaches: threshold-based dose painting by contours (DPBC) with voxel-based dose painting by numbers (DPBN)...
  57. pmc Hematological changes as prognostic indicators of survival: similarities between Gottingen minipigs, humans, and other large animal models
    Maria Moroni
    Radiation Countermeasures Program, Scientific Research Department, Armed Forces Radiobiology Research Institute, Uniformed Services University of the Health Sciences, Bethesda, Maryland, United States of America
    PLoS ONE 6:e25210. 2011
    ..We have previously shown that the Gottingen minipig manifests hematopoietic ARS phases and symptoms similar to those observed in canines, NHPs, and humans...
  58. ncbi Moving from gamma passing rates to patient DVH-based QA metrics in pretreatment dose QA
    Heming Zhen
    Department of Medical Physics, University of Wisconsin, Madison, WI, USA
    Med Phys 38:5477-89. 2011
    ....
  59. pmc New radiometric ages for the BH-1 hominin from Balanica (Serbia): implications for understanding the role of the Balkans in Middle Pleistocene human evolution
    William J Rink
    School of Geography and Earth Sciences, McMaster University, Hamilton, Ontario, Canada
    PLoS ONE 8:e54608. 2013
    ....
  60. ncbi Individualized dosimetry in patients undergoing therapy with (177)Lu-DOTA-D-Phe (1)-Tyr (3)-octreotate
    Mattias Sandström
    Department of Oncology, Radiology and Clinical Immunology, Uppsala University Hospital, 751 85, Uppsala, Sweden
    Eur J Nucl Med Mol Imaging 37:212-25. 2010
    ..The aim of this study was to investigate the feasibility and reliability of individualized dosimetry based on SPECT in comparison to conventional planar imaging...
  61. pmc Feasibility and early clinical assessment of flattening filter free (FFF) based stereotactic body radiotherapy (SBRT) treatments
    Marta Scorsetti
    Radiotherapy and Radiosurgery, Humanitas Cancer Center, Istituto Clinico Humanitas, Rozzano Milano, Italy
    Radiat Oncol 6:113. 2011
    ..To test feasibility and safety of clinical usage of Flattening Filter Free (FFF) beams for delivering ablative stereotactic body radiation therapy (SBRT) doses to various tumor sites, by means of Varian TrueBeam™ (Varian Medical Systems)...
  62. ncbi Quantifying the degree of conformity in radiosurgery treatment planning
    Nicoletta J Lomax
    Klinik Im Park, Gamma Knife Centre, Zurich, Switzerland
    Int J Radiat Oncol Biol Phys 55:1409-19. 2003
    ..To compare different parameters used to quantify the quality of a treatment plan and to evaluate the dose conformity and coverage clinically achieved using gamma knife radiosurgery...
  63. pmc Dosimetric comparison of Acuros XB deterministic radiation transport method with Monte Carlo and model-based convolution methods in heterogeneous media
    Tao Han
    Department of Radiation Physics, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA
    Med Phys 38:2651-64. 2011
    ..The goal of this study was to compare AXB performance to Monte Carlo (MC) and two standard clinical convolution methods: the anisotropic analytical algorithm (AAA) and the collapsed-cone convolution (CCC) method...
  64. pmc Reduction of the secondary neutron dose in passively scattered proton radiotherapy, using an optimized pre-collimator/collimator
    David J Brenner
    Center for Radiological Research, Columbia University Medical Center, 630 West 168th Street, New York, NY 10032, USA
    Phys Med Biol 54:6065-78. 2009
    ....
  65. pmc UV effects in tooth enamel and their possible application in EPR dosimetry with front teeth
    S Sholom
    Laboratory of External Exposure Dosimetry, Research Center for Radiation Medicine, Kiev, Ukraine
    Health Phys 98:360-8. 2010
    ..The technique developed here to quantify and subtract the UV contribution to the measured tooth is currently limited to cumulative dose measurements with a component of UV equivalent dose equal to or greater than 300 mGy...
  66. pmc Estimated cumulative radiation dose from PET/CT in children with malignancies: a 5-year retrospective review
    Soni C Chawla
    Department of Radiology, Olive View UCLA Medical Center, 14445 Olive View Drive, 2 D115, Sylmar, CA, USA
    Pediatr Radiol 40:681-6. 2010
    ..The increasing use of serial PET/CT scans in the management of pediatric malignancies raises the important consideration of radiation exposure in children...
  67. pmc Dosimetric parameter predicting the deterioration of hepatic function after helical tomotherapy in patients with unresectable locally advanced hepatocellular carcinoma
    Seok Hyun Son
    Department of Radiation Oncology, College of Medicine, The Catholic University of Korea, Seoul, Korea
    Radiat Oncol 8:11. 2013
    ..The purpose of this study was to identify parameters capable of predicting the deterioration of hepatic function after helical tomotherapy in patients with unresectable locally advanced hepatocellular carcinoma...
  68. ncbi Evaluation of the Delta4 phantom for IMRT and VMAT verification
    James L Bedford
    Joint Department of Physics, The Institute of Cancer Research and The Royal Marsden NHS Foundation Trust, Downs Road, Sutton, Surrey SM2 5PT, UK
    Phys Med Biol 54:N167-76. 2009
    ..The Delta(4) is a complex device and requires careful benchmarking, but following the successful completion of these measurements, the Delta(4) has been introduced into clinical use...
  69. ncbi Late residual gamma-H2AX foci in murine skin are dose responsive and predict radiosensitivity in vivo
    Nirmal Bhogal
    Applied Molecular Oncology and Radiation Medicine Program, Ontario Cancer Institute Princess Margaret Hospital, Toronto, Ontario, Canada
    Radiat Res 173:1-9. 2010
    ..This technique may be a useful biodosimeter to determine dose at times up to 1 week after accidental or catastrophic radiation exposure in vivo...
  70. ncbi Minimizing and communicating radiation risk in pediatric nuclear medicine
    Frederic H Fahey
    Division of Nuclear Medicine and Molecular Imaging, Children s Hospital Boston, Boston, Massachusetts 02115, USA
    J Nucl Med 52:1240-51. 2011
    ..Approaches for effective communication of risk to patients' families are discussed. Lastly, radiation dose reduction in pediatric nuclear medicine is explicated...
  71. ncbi Verification and dosimetric impact of Acuros XB algorithm on intensity modulated stereotactic radiotherapy for locally persistent nasopharyngeal carcinoma
    Monica W K Kan
    Department of Oncology, Princess Margaret Hospital, Hong Kong SAR, China
    Med Phys 39:4705-14. 2012
    ..The dosimetric accuracy of using AXB in predicting air∕tissue interface doses from an open single small field in a simple geometric phantom and intensity modulated small fields in an anthropomorphic phantom was also investigated...
  72. pmc Electron paramagnetic resonance dosimetry for a large-scale radiation incident
    Harold M Swartz
    Dartmouth Medical School, Hanover, NH 03755, USA
    Health Phys 103:255-67. 2012
    ..The authors conclude that electron paramagnetic resonance dosimetry is likely to be a useful part of triage for a large-scale radiation incident...
  73. ncbi Biological effectiveness of (12)C and (20)Ne ions with very high LET
    Joanna Czub
    Institute of Physics, Jan Kochanowski University, ul Swietokrzyska 15, 25 406 Kielce, Poland
    Int J Radiat Biol 84:821-9. 2008
    ..To determine the relationship between the relative biological effectiveness (RBE) for cell inactivation and linear energy transfer (LET) in the Bragg peak region of (12)C and (20)Ne ions...
  74. pmc Polymer gel dosimetry
    C Baldock
    Institute of Medical Physics, School of Physics, University of Sydney, Australia
    Phys Med Biol 55:R1-63. 2010
    ..The fundamental science underpinning polymer gel dosimetry is reviewed along with the various evaluation techniques. Clinical dosimetry applications of polymer gel dosimetry are also presented...
  75. ncbi Quality assurance of dosimetry and the impact on sample size in randomized clinical trials
    Morten N Pettersen
    Institute for Cancer Research, Rikshospitalet Radiumhospitalet Medical Centre, Oslo, Norway
    Radiother Oncol 86:195-9. 2008
    ..The aim of this study was to investigate the impact of appropriate dosimetry quality assurance (QA) on patient number required in radiotherapy randomized control trials (RCT)...
  76. ncbi Evidence of extranuclear cell sensitivity to alpha-particle radiation using a microdosimetric model. I. Presentation and validation of a microdosimetric model
    N Chouin
    INSERM, U892, Nantes, F 44093 France
    Radiat Res 171:657-63. 2009
    ..Good agreements were also observed with previously published results...
  77. ncbi 177Lu-[DOTA0,Tyr3] octreotate therapy in patients with disseminated neuroendocrine tumors: Analysis of dosimetry with impact on future therapeutic strategy
    Michael Garkavij
    Department of Oncology, Lund University and Lund University Hospital, Lund, Sweden
    Cancer 116:1084-92. 2010
    ..In commonly used dosimetry methods, planar imaging is used for determination of the residence time, whereas the kidney mass is determined from a computed tomography (CT) scan...
  78. ncbi Characteristics of a new polymer gel for high-dose gradient dosimetry using a micro optical CT scanner
    G Massillon-Jl
    Ionizing Radiation Division, National Institute of Standards and Technology, Gaithersburg, MD 20899, USA
    Appl Radiat Isot 68:144-54. 2010
    ..The response of the gel was found to have no dose rate dependence for dose rates ranging from 3.7 to 15mGy/s. Within the measurement uncertainty, the gel response is more sensitive for beta particles than high energy photons...
  79. ncbi Clinical application of radiophotoluminescent glass dosimeter for dose verification of prostate HDR procedure
    Shih Ming Hsu
    Department of Biomedical Imaging and Radiological Science, China Medical University, Taichung, Taiwan, Republic of China
    Med Phys 35:5558-64. 2008
    ..This study concludes that the RPLGD is a promising and reliable dosimeter for HDR-BT in vivo dosimetry with clinically acceptable accuracy...
  80. ncbi Estimating risk of cancer associated with radiation exposure from 64-slice computed tomography coronary angiography
    Andrew J Einstein
    Department of Medicine, Division of Cardiology and Department of Radiology, Columbia University College of Physicians and Surgeons, New York, New York 10032, USA
    JAMA 298:317-23. 2007
    ....
  81. pmc Four-dimensional dosimetry validation and study in lung radiotherapy using deformable image registration and Monte Carlo techniques
    Tzung Chi Huang
    Department of Biomedical Imaging and Radiological Sciences, National Yang Ming University, Taiwan
    Radiat Oncol 5:45. 2010
    ....
  82. ncbi Dosimetric comparison of IMRT vs. 3D conformal radiotherapy in the treatment of cancer of the cervical esophagus
    Louis Fenkell
    Department of Radiation Oncology, Princess Margaret Hospital, Toronto, ON, Canada
    Radiother Oncol 89:287-91. 2008
    ..Radiotherapy planning for cervical esophageal cancer is challenging. We compared IMRT and 3D conformal radiotherapy (CRT) with respect to conformality of target coverage and normal tissue sparing...
  83. pmc Can megavoltage computed tomography reduce proton range uncertainties in treatment plans for patients with large metal implants?
    Wayne D Newhauser
    Department of Radiation Physics, University of Texas M D Anderson Cancer Center, Houston, TX 77030, USA
    Phys Med Biol 53:2327-44. 2008
    ..In this approach, the kVCT images provided good delineation of soft tissues due to high-contrast resolution, and the streak-free MVCT images provided smaller range uncertainties because they did not require artifact correction...
  84. ncbi Flattening filter free beams in SBRT and IMRT: dosimetric assessment of peripheral doses
    Gabriele Kragl
    Department of Radiotherapy, Div Medical Radiation Physics, Medical University of Vienna, Austria
    Z Med Phys 21:91-101. 2011
    ..The aim of the present study was to determine the impact of unflattened beams on peripheral dose for advanced treatment techniques with a large number of MUs...
  85. ncbi Commissioning of photon beams of a flattening filter-free linear accelerator and the accuracy of beam modeling using an anisotropic analytical algorithm
    Jan Hrbacek
    Department of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland
    Int J Radiat Oncol Biol Phys 80:1228-37. 2011
    ..To evaluate the accuracy of beam modeling under physical conditions using an anisotropic analytical algorithm...
  86. pmc A 4D IMRT planning method using deformable image registration to improve normal tissue sparing with contemporary delivery techniques
    Xiaoqiang Li
    Department of Radiation Physics, The University of Texas, MD Anderson Cancer Center, Houston, Texas 77030, USA
    Radiat Oncol 6:83. 2011
    ..The dose volume histograms of cumulative 4D doses to the PTV50, clinical target volume, lung, spinal cord, liver, and heart on the 4D repeat CTs for the two patients were similar to those for the 4D dose at the time of original planning...
  87. ncbi Monte Carlo dosimetry for targeted irradiation of individual cells using a microbeam facility
    S Incerti
    CNRS IN2P3, Centre d Etudes Nucléaires de Bordeaux Gradignan, UMR 5797, Gradignan F 33175, France
    Radiat Prot Dosimetry 133:2-11. 2009
    ..Such phantoms are built from confocal microscopy imaging and from ion beam chemical elemental analysis. Results are presented for single-cell irradiation with 3 MeV incident alpha particles...
  88. ncbi A 3D pencil-beam-based superposition algorithm for photon dose calculation in heterogeneous media
    L Tillikainen
    Varian Medical Systems Finland Oy, Paciuksenkatu 21, FIN 00270 Helsinki, Finland
    Phys Med Biol 53:3821-39. 2008
    ..The presented method was found to be accurate in a wide range of conditions making it suitable for clinical planning purposes...
  89. ncbi Dosimetric validation of the Acuros XB Advanced Dose Calculation algorithm: fundamental characterization in water
    Antonella Fogliata
    Oncology Institute of Southern Switzerland, Medical Physics Unit, Bellinzona, Switzerland
    Phys Med Biol 56:1879-904. 2011
    ..The basic validation of the Acuros XB algorithm was therefore considered satisfactory for both conventional photon beams as well as for FFF beams of new generation linacs such as the Varian TrueBeam...
  90. ncbi Dosimetric validation of the anisotropic analytical algorithm for photon dose calculation: fundamental characterization in water
    Antonella Fogliata
    Oncology Institute of Southern Switzerland, Medical Physics Unit, Bellinzona, Switzerland
    Phys Med Biol 51:1421-38. 2006
    ..Additional tests were carried out for enhanced dynamic wedges with results comparable to previous results. The basic dosimetric validation of the AAA was therefore considered satisfactory...
  91. ncbi 68Ga-DOTANOC: biodistribution and dosimetry in patients affected by neuroendocrine tumors
    C Pettinato
    Health Physics, A O S Orsola Malpighi, Bologna, Italy
    Eur J Nucl Med Mol Imaging 35:72-9. 2008
    ..The aim of this work was the evaluation of biodistribution and radiation dosimetry of (68)Ga-DOTANOC in patients affected by neuroendocrine tumors...
  92. ncbi Dosimetry audit for a multi-centre IMRT head and neck trial
    Catharine H Clark
    Department of Physics, Royal Marsden NHS Foundation Trust, London, UK
    Radiother Oncol 93:102-8. 2009
    ..The dosimetry audit goals were to verify the plan delivery in participating centres, ascertain what tolerances were suitable for head and neck IMRT trials and develop an IMRT credentialing program...
  93. ncbi Improving dose homogeneity in large breasts by IMRT: efficacy and dosimetric accuracy of different techniques
    Yasser Abo-Madyan
    Department of Radiation Oncology, Mannheim Medical Center, University of Heidelberg, Mannheim, Germany
    Strahlenther Onkol 184:86-92. 2008
    ....
  94. ncbi Commissioning and quality assurance of RapidArc radiotherapy delivery system
    C Clifton Ling
    Varian Medical Systems, Palo Alto, CA, USA
    Int J Radiat Oncol Biol Phys 72:575-81. 2008
    ..We developed RapidArc system commissioning and quality assurance (QA) procedures...
  95. ncbi A motion phantom study on helical tomotherapy: the dosimetric impacts of delivery technique and motion
    Brian Kanagaki
    Department of Engineering Physics, University of Virginia, Charlottesville, VA 22908, USA
    Phys Med Biol 52:243-55. 2007
    ..The lack of adverse synchronization patterns from both results validate that HT is a safe technique for treating moving target and hypofractionation...
  96. ncbi Dosimetric evaluation of a new OneDose MOSFET for Ir-192 energy
    Rajesh A Kinhikar
    Department of Medical Physics, Tata Memorial Hospital, Parel, Mumbai 400 012, India
    Phys Med Biol 51:1261-8. 2006
    ....
  97. ncbi Polymer gel dosimeters with reduced toxicity: a preliminary investigation of the NMR and optical dose-response using different monomers
    R J Senden
    Department of Chemical Engineering, Queen s University, Kingston, Ont K7L 3N6, Canada
    Phys Med Biol 51:3301-14. 2006
    ..The optical dose-response, measured in terms of the attenuation coefficient for each polymer gel dosimeter, showed potential for the use of optical imaging techniques in future studies...
  98. ncbi Monte Carlo based IMRT dose verification using MLC log files and R/V outputs
    Wei Luo
    Department of Radiation Oncology, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, USA
    Med Phys 33:2557-64. 2006
    ..2 mm can result in a target dose error of about 1.0%...
  99. ncbi Comparison of dose calculation algorithms in phantoms with lung equivalent heterogeneities under conditions of lateral electronic disequilibrium
    P Carrasco
    Servei de Radiofísica i Radioprotecció, Hospital de la Santa Creu i Sant Pau, St Antoni Maria Claret 167, 08025 Barcelona, Spain
    Med Phys 31:2899-911. 2004
    ....
  100. ncbi Monte Carlo simulations for configuring and testing an analytical proton dose-calculation algorithm
    Wayne Newhauser
    Department of Radiation Physics, The University of Texas M D Anderson Cancer Center, Houston, Texas, USA
    Phys Med Biol 52:4569-84. 2007
    ..The model presented here provided a means to reduce by several months the time required to prepare an analytical treatment planning system for patient treatments...
  101. ncbi A comparison of cellular irradiation techniques with alpha particles using the Geant4 Monte Carlo simulation toolkit
    S Incerti
    Centre d Etudes Nucléaires de Bordeaux Gradignan, CNRS IN2P3, Universite Bordeaux 1, Le Haut Vigneau, Gradignan Cedex, France
    Radiat Prot Dosimetry 122:327-9. 2006
    ..The simulation allows the calculation of hit distributions among the cellular population as well as the absorbed dose for two typical cellular geometries...

Research Grants63

  1. 18F-Mefway PET for Human Aging and Alzheimer's Disease
    Jogeshwar Mukherjee; Fiscal Year: 2013
    ..18F-Mefway will be evaluated in well-characterized groups of control, MCI and AD subjects and results will be correlated with clinical outcome measures of 18F-FDG, MRI and neuropsychological tests. ..
  2. CD45 Pretargeted Radioimmunotherapy for AML
    Oliver W Press; Fiscal Year: 2013
    ....
  3. AccuTemp Sensor: Radiometry based non-invasive continuous core body temperature m
    DOUGLAS O REUDINK; Fiscal Year: 2013
    ..Thermimage's development of the novel AccuTemp Sensor will safely and reliably monitor deep brain temperature non-invasively, assisting greatly in creating best outcomes for patients, physicians and institutions. ..
  4. Imaging Adrenergic Stimulation of Brown Adipose Tissue
    Jogeshwar Mukherjee; Fiscal Year: 2012
    ..Development of the adrenergic neurotransmitter receptor imaging methods will strongly complement ongoing imaging approaches for obesity and diabetes. ..
  5. Radiation Dose-Dependent Interventions
    George Earl Georges; Fiscal Year: 2010
    ....
  6. PET Imaging Agents for a4b2 Nicotinic Receptors
    Jogeshwar Mukherjee; Fiscal Year: 2013
    ..The overall proposed research in this application will also support investigations in other disorders such as Parkinson's disease and schizophrenia. ..
  7. Radiolabeled RGD Peptides for Breast Cancer Imaging and Therapy
    Zhen Cheng; Fiscal Year: 2010
    ..The same ligands labeled with therapeutic isotopes will allow targeted internal radiotherapy of integrin positive tumors. ..
  8. Development of PET radioligands for cerebral cannabinoid receptor (CB1)
    Andrew G Horti; Fiscal Year: 2011
    ....
  9. Extrathalamic nAChR-PET for Imaging Neurodegeneration
    Martin G Pomper; Fiscal Year: 2013
    ....
  10. PRETARGETED RADIOIMMUNOTHERAPY OF CD20+ LYMPHOMAS
    Oliver W Press; Fiscal Year: 2012
    ..We anticipate rapid translation of the results of these preclinical experiments into our clinical RIT program for human Non- Hodgkin's lymphomas. ..
  11. [18F]FPEB Studies of the mGluR5 Receptor and Methamphetamine Abuse
    ROBERT MICHAEL KESSLER; Fiscal Year: 2013
    ..The proposed studies will be the first studies the of mGluR5 receptor in METH abuse in humans, and will significantly enhance our knowledge of the role of the mGluR5 receptor in humans abusing METH. ..
  12. Noninvasive Assessment of Pancreatic Beta-Cell Mass
    Xiankai Sun; Fiscal Year: 2013
    ..The potential risk of this longitudinal imaging technique and radiation dosimetry will be determined. Upon the successful completion of this project, we expect to have a safe imaging technique available for further clinical evaluation. ..
  13. Non-Invasive Measurements of Brown Adipose Tissues
    FRED STERZER; Fiscal Year: 2011
    ..goal of this work is to replace the radiation and cost of PET/CT with a safe, faster, and cheaper microwave radiometry method...
  14. Targeted Radiotherapy/Chemotherapy Treatment of Prostate Cancer
    Timothy J Hoffman; Fiscal Year: 2013
    ....
  15. Pretherapy 124I-MIBG Dosimetry for Planning 131I-MIBG Neuroblastoma Therapy
    Youngho Seo; Fiscal Year: 2013
    ..The outcomes of the individualized prescription of the 131I-MIBG treatment will be descriptively compared to the therapy outcomes, particularly the primary tumor size reduction. ..
  16. Novel HDAC Class III Specific Radiotracers for PET Imaging.
    JURI GEORGE GELOVANI; Fiscal Year: 2013
    ..abstract_text> ..
  17. Ultrasmall wireless dosimeters for in vivo radiation dosimetry
    MARGARET A REYNOLDS; Fiscal Year: 2013
    ....
  18. Port wine stain treatment for infants and young children
    Guillermo Aguilar; Fiscal Year: 2006
    ..S.) and pulsed photothermal radiometry (PER...
  19. BORON NEUTRON CAPTURE THERAPY OF OCULAR MELANOMA
    Samuel Packer; Fiscal Year: 1992
    ..This information along with radiation dosimetry and phase I clinical studies of the biodistribution of BPA in humans will lead to clinical therapy trials with BNCT...
  20. Dose Reduction in Pediatric Molecular Imaging
    George Sgouros; Fiscal Year: 2013
    ....
  21. NEW CNS DOPAMINE RECEPTOR IMAGING AGENTS
    HANK KUNG; Fiscal Year: 2002
    ....
  22. Realistic Accurate Dosimulation (RAD)
    HANS GREGORY SCHANTZ; Fiscal Year: 2013
    ..The substantial improvements in Dosimulation systems made possible by the proposed RAD effort would enable Q-Track to serve the Emergency Responder training market as well. ..
  23. Development of GRP Receptor-Avid Radiopharmaceuticals
    Timothy Hoffman; Fiscal Year: 2006
    ..Utilizing this selective radiotherapeutic targeting approach, either alone or combined with other chemotherapeutics, may provide new opportunities to manage and treat breast cancer. ..
  24. STERILE DOCKING DEVICE FOR CENTRAL VENOUS CATHETER HUBS
    KENNETH CARR; Fiscal Year: 2000
    ..by reflection coefficient determination rather than by the more complicated and costly alternative of microwave radiometry. Finally, the catheter/adapter connector must be designed so that it heats uniformly (no "cold spots") and be ..
  25. 4D Visible Human Modeling for Radiation Dosimetry
    Xie George Xu; Fiscal Year: 2010
    ..4).To establish an internet-based information-sharing resource on virtual-human motion simulation and radiation dosimetry. ..
  26. Improved polymer gels for radiation dosimetry by MRI
    John Gore; Fiscal Year: 2005
    ..Overall we aim to produce much improved gels for practical applications and obtain a better and more quantitative understanding of how they respond to radiation. ..
  27. Intralumbar Injection for Cancer Therapy using I-131 Nal
    Franklin Wong; Fiscal Year: 2004
    ..Correlation of dosages and dosimetry with toxicity and/or efficacy will be used to design future Phase II/III studies. ..
  28. OPTICS AND PHOTOTOXICITY IN HUMAN SKIN
    John Parrish; Fiscal Year: 1993
    ..New optical diagnostic techniques will also be developed including pulsed infrared radiometry for noninvasive measurement of absorption spectra in tissues and for detection of buried layers in tissues such ..
  29. THERMOMETRY FOR ABLATION OF BENIGN PROSTATIC HYPERPLASIA
    KENNETH CARR; Fiscal Year: 2000
    ..of monitoring both urethral and intraprostatic temperature during TUMT through the use of passive microwave radiometry (PMR). PMR has several advantages over existing fiberoptic thermal sensing systems...
  30. IMAGING THROMBOEMBOLISM WITH FIBRIN AVID TC-99M-PEPTIDE
    Mathew Thakur; Fiscal Year: 2002
    ..Because there are no agents currently available than can scintigraphically provide "hot spot" images of old (24 hr or older) clots and PE, the commercial potential for this agent is very high. ..
  31. RADIATION DOSIMETRY FOR EPIDEMIOLOGIC STUDIES
    Marilyn Stovall; Fiscal Year: 1993
    ..It is anticipated that other populations will be studied...
  32. SPATIALLY SELECTIVE COAGULATION OF HYPERVASCULAR LESIONS
    Bahman Anvari; Fiscal Year: 2004
    ..ex-vivo, and in-vivo animal model levels in conjunction with one-dimensional inversion of pulsed photothermal radiometry (PPTR) data to "recommend" optimum CSC and laser irradiation parameters for a specific lesion and skin type; and ..
  33. Endothelin Receptor Imaging of Cancer with PET
    Zsolt Szabo; Fiscal Year: 2007
    ..They have the potential to improve selection of cancer patients for treatment with endothelin antagonists. [unreadable] [unreadable] [unreadable]..
  34. Evaluation of Iodorotenone, A SPECT Perfusion Tracer
    Henry VanBrocklin; Fiscal Year: 2005
    ..The potential clinical impact of an improved flow tracer such as [123I]iodorotenone is far-reaching. ..
  35. Development of radioligands with improved brain kinetics for imaging nAChR by PET
    ANDREW HORTI; Fiscal Year: 2009
    ....
  36. Conformal Heat and Brachytherapy Surface Applicator
    JAIME SCHLORFF; Fiscal Year: 2007
    ..We will have established appropriate treatment protocols and verified clinical performance. And we will have manufacturing capability to produce applicators that meet the needs of the cancer treatment community. [unreadable] [unreadable]..
  37. ELECTRON DOSIMETRY IN RADIOIMMUNOTHERAPY
    Cheuk Kwok; Fiscal Year: 1991
    ..The end product of the proposal will be validated computer programs which may eventually be used for routine treatment planning of radioimmunotherapy...
  38. Use of Visible Human Data For Patient Dosimetry
    Xie Xu; Fiscal Year: 2004
    ..3) To evaluate the degrees to which improved anatomical representation of internal organ structures influences estimate of organ dose in adult patients who are undergoing a typical nuclear medicine procedure. ..
  39. PULSED PHOTOTHERMAL RADIOMETRY OF PORT WINE STAIN
    J Nelson; Fiscal Year: 1992
    ..to (a) gain an understanding of and implement non-invasive device based on the principles of pulsed photothermal radiometry (PPTR) for application in the treatment of port- wine stain (PWS) and (b) develop a more efficacious and safe ..
  40. TEA-CO2 DEBRIDEMENT OF BURN ESCHAR (7130-260)
    David Rosen; Fiscal Year: 1991
    ..Also investigated will be the utility of using fast, real-time photothermal radiometry as feedback guidance for determining when the necrotic/viable tissue interface has been reached...
  41. ULTRASOUND APPLICATORS FOR THERMOBRACHYTHERAPY
    Chris Diederich; Fiscal Year: 1999
    ..The development of this heating technique will provide an improved heating modality ready for Phase I/II trials of long duration simultaneous thermoradiotherapy. ..
  42. REAL-TIME CT PROSTATE BRACHTHERAPY USING IMAGE FUSION
    Brian Davis; Fiscal Year: 2001
    ....
  43. NON-INVASIVE SENSING OF SUBCUTANEOUS TEMPERATURES
    Alan Barrett; Fiscal Year: 1980
    ..cm. The techniques to be developed or investigated are (a) reflection-compensating radiometry, which measures both temperature and emissivity; (b) multimode antennas, which form beams of different ..
  44. An Image Guided Small Animal Radiation Research Platform
    John Wong; Fiscal Year: 2007
    ..The collaborative efforts are best coordinated in a Bioengineering Research Partnership (BRP). An Oversight Group is formed to evaluate the progress of the BRP, and to help identify opportunities and hypotheses for future research. ..
  45. INTERNATIONAL CONFERENCE ON MEDICAL PHYSICS
    HARACIO FARACH; Fiscal Year: 1990
    ..A Round Table of the Third World Ass. of Medical Physics (TWAMP) will also be organized and held at the end of the conference...
  46. Conformal Heat and Brachytherapy Surface Applicator
    JAIME SCHLORFF; Fiscal Year: 2003
    ..We will verify that radiation does not adversely affect heating patterns or temperature monitoring accuracy and that heat applicator and temperature monitoring do not adversely affect radiation dosimetry. ..
  47. Radiometry Controlled Conformal Array Heat Applicator
    Paul Stauffer; Fiscal Year: 2006
    ..abstract_text> ..
  48. SPECIAL TOPICS IN RADIATION DOSIMETRY
    JOHN SPOKAS; Fiscal Year: 1980
    ..A fuller understanding of depth-dose curves for diverse neutron beams is sought with particular emphasis on the role of chamber geometry and the dose defect at the exit face of a phantom...
  49. BRAIN TEMPERATURE MONITORING IN NEONATES
    KENNETH CARR; Fiscal Year: 2005
    ..This proposal will evaluate temperature monitoring using noninvasive dual frequency microwave radiometry of the skull...
  50. EARLY DETECTION OF NEONATAL & PEDIATRIC EXTRAVASATIONS
    KENNETH CARR; Fiscal Year: 1999
    ..The proposed research is intended to evaluate newly available Passive Microwave Radiometry (PMR) technology as a modality for early detection of extravasation events in children...
  51. ATM mutations in breast cancer - a functional approach
    Patrick Concannon; Fiscal Year: 2007
    ..abstract_text> ..
  52. ULTRASOUND SYSTEMS FOR SIMULTANEOUS THERMORADIOTHERAPY
    Eduardo Moros; Fiscal Year: 1999
    ..This will lead to phase I/II clinical research trials to assess the benefits/complications of this treatment approach, thus making new and important contributions in the field of cancer therapy with radiation and hyperthermia. ..
  53. NOVEL, FAST, RELIABLE&INEXPENSIVE RADIATION DOSIMETER
    Gavin Braithwaite; Fiscal Year: 2001
    ....
  54. CONTROLLED INTRACAVITARY PROSTATE CANCER HYPERTHERMIA
    KENNETH CARR; Fiscal Year: 1993
    ..This research is intended to introduce and evaluate Passive Microwave Radiometry (PMR) technology for the treatment of prostate Cancer...
  55. DOSIMETRIC MARKERS FOR IMAGE GUIDED RADIATION THERAPY
    THOMAS CETAS; Fiscal Year: 2000
    ..Three seeds could establish a field edge precisely for tumors near critical organs. Combining the two concepts, Marker RDS permit image guided therapy with measured doses. ..
  56. EARLY DETECTION OF NEONATAL AND PEDIATRIC EXTRAVASATIONS
    KENNETH CARR; Fiscal Year: 1993
    ..The proposed research is intended to evaluate newly available Passive Microwave Radiometry (PMR) technology as a modality for early detection of extravasation events in children...
  57. OPTIMIZING MICROWAVE SCANNING TO DETECT BREAST CANCER
    RICHARD GRABOWY; Fiscal Year: 1991
    ..The Phase I program proved the feasibility of using a multiple antenna microwave radiometry system for detecting "hot spots" embedded within a two-layer phantom model representative of biological tissue...
  58. Radiation Dosimetry and Imaging Devices
    Gordhan Patel; Fiscal Year: 2001
    ..The dosimeters can be used for monitoring nuclear radiation by nuclear power plants, research nuclear reactors, nuclear powered ship/submarines. ..
  59. POLYMER GEL FOR CLINICAL 3D RADIATION DOSIMETRY BY MRI
    MAREK MARYANSKI; Fiscal Year: 1993
    ..These studies will prepare the ground for the development of more efficient polymer-gels in Phase II...
  60. THERMAL CHARACTERIZATION OF HUMAN BREAST TUMORS
    KENNETH CARR; Fiscal Year: 1999
    ..This Phase II proposal is designed to obtain noninvasive thermal information using passive microwave radiometry in both breasts of approximately 1000 women scheduled to have needle localization procedures and breast biopsy...
  61. MICROWAVE RADIOMETRY AS AN ADJUNCT TO MAMMOGRAPHY
    KENNETH CARR; Fiscal Year: 2006
    ..The data obtained from this study could lead to the development of improved detection techniques and equipment, based on noninvasive thermal sensing, as an adjunct to mammography. ..
  62. PHYSICS CENTER FOR COLLABORATIVE OCULAR MELANOMA STUDY
    William Hanson; Fiscal Year: 1999
    ..Knowledge gained will be communicated to the radiologic and opthamalogic communities. ..
  63. 3-D radiation dosimetry by stable color formation
    ALAN APPLEBY; Fiscal Year: 2003
    ....