exercise test

Summary

Summary: Controlled physical activity, more strenuous than at rest, which is performed in order to allow assessment of physiological functions, particularly cardiovascular and pulmonary, but also aerobic capacity. Maximal (most intense) exercise is usually required but submaximal exercise is also used. The intensity of exercise is often graded, using criteria such as rate of work done, oxygen consumption, and heart rate.

Top Publications

  1. ncbi Exercise capacity and mortality among men referred for exercise testing
    Jonathan Myers
    Division of Cardiovascular Medicine, Stanford University Medical Center and the Veterans Affairs Palo Alto Health Care System, Palo Alto, Calif CA 94304, USA
    N Engl J Med 346:793-801. 2002
  2. ncbi Meaningful change and responsiveness in common physical performance measures in older adults
    Subashan Perera
    Division of Geriatric Medicine and Department of Biostatistics, Univeristy of Pittsburgh, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    J Am Geriatr Soc 54:743-9. 2006
  3. ncbi The six-minute walk test
    Paul L Enright
    University of Arizona, AHSC 2342, PO Box 245030, 1501 N Campbell Avenue, Tucson AZ 85724 3030, USA
    Respir Care 48:783-5. 2003
  4. ncbi Influences of cardiorespiratory fitness and other precursors on cardiovascular disease and all-cause mortality in men and women
    S N Blair
    Cooper Institute for Aerobics Research, Dallas, Tex 75230, USA
    JAMA 276:205-10. 1996
  5. ncbi Standard reference for the six-minute-walk test in healthy children aged 7 to 16 years
    Albert M Li
    Department of Pediatrics, and Centre for Epidemiology and Biostatistics, 6th Floor, Clinical Sciences Building, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Am J Respir Crit Care Med 176:174-80. 2007
  6. ncbi Reference values for the 6-min walk test in healthy subjects 20-50 years old
    Alfredo Chetta
    Department of Clinical Sciences, Section of Respiratory Diseases, University of Parma, Italy
    Respir Med 100:1573-8. 2006
  7. ncbi Hierarchy of individual calibration levels for heart rate and accelerometry to measure physical activity
    Søren Brage
    MRC Epidemiology Unit, Cambridge CB1 9NL, UK
    J Appl Physiol (1985) 103:682-92. 2007
  8. ncbi Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology
    Kim Fox
    Department of Cardiology, Royal Brompton Hospital, London, UK
    Eur Heart J 27:1341-81. 2006
  9. ncbi Six-minute walk test in children and adolescents
    Ralf Geiger
    Department of Pediatrics, Clinical Division of Cardiology, Pulmology, Allergology, and Cystic Fibrosis, Innsbruck Medical University, Innsbruck, Austria
    J Pediatr 150:395-9, 399.e1-2. 2007
  10. ncbi Predictors of success and failure in pulmonary rehabilitation
    R Garrod
    School of Physiotherapy, Faculty of Health and Social Care Sciences, St George s, University of London, UK
    Eur Respir J 27:788-94. 2006

Detail Information

Publications334 found, 100 shown here

  1. ncbi Exercise capacity and mortality among men referred for exercise testing
    Jonathan Myers
    Division of Cardiovascular Medicine, Stanford University Medical Center and the Veterans Affairs Palo Alto Health Care System, Palo Alto, Calif CA 94304, USA
    N Engl J Med 346:793-801. 2002
    ..There is also uncertainty regarding the predictive power of exercise capacity relative to other clinical and exercise-test variables...
  2. ncbi Meaningful change and responsiveness in common physical performance measures in older adults
    Subashan Perera
    Division of Geriatric Medicine and Department of Biostatistics, Univeristy of Pittsburgh, 3471 Fifth Avenue, Pittsburgh, PA 15213, USA
    J Am Geriatr Soc 54:743-9. 2006
    ..To estimate the magnitude of small meaningful and substantial individual change in physical performance measures and evaluate their responsiveness...
  3. ncbi The six-minute walk test
    Paul L Enright
    University of Arizona, AHSC 2342, PO Box 245030, 1501 N Campbell Avenue, Tucson AZ 85724 3030, USA
    Respir Care 48:783-5. 2003
    ..If the 6MWD is low, thoroughly search for the cause(s) of the impairment. Better 6MWD reference equations will be published in the future, so be sure you are using the best available reference equations...
  4. ncbi Influences of cardiorespiratory fitness and other precursors on cardiovascular disease and all-cause mortality in men and women
    S N Blair
    Cooper Institute for Aerobics Research, Dallas, Tex 75230, USA
    JAMA 276:205-10. 1996
    ..We calculated CVD and all-cause death rates for low (least fit 20%), moderate (next 40%), and high (most fit 40%) fitness categories by strata of smoking habit, cholesterol level, blood pressure, and health status...
  5. ncbi Standard reference for the six-minute-walk test in healthy children aged 7 to 16 years
    Albert M Li
    Department of Pediatrics, and Centre for Epidemiology and Biostatistics, 6th Floor, Clinical Sciences Building, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong
    Am J Respir Crit Care Med 176:174-80. 2007
    ..We have previously reported that the six-minute-walk test (6MWT) is a reliable and valid functional test for assessing exercise tolerance and endurance. There is a lack of pediatric standard reference for the 6MWT...
  6. ncbi Reference values for the 6-min walk test in healthy subjects 20-50 years old
    Alfredo Chetta
    Department of Clinical Sciences, Section of Respiratory Diseases, University of Parma, Italy
    Respir Med 100:1573-8. 2006
    ..This study confirms the relevant effect of anthropometrics on walking capacity and suggests that when rating dyspnea, the change in heart rate during walking should be considered...
  7. ncbi Hierarchy of individual calibration levels for heart rate and accelerometry to measure physical activity
    Søren Brage
    MRC Epidemiology Unit, Cambridge CB1 9NL, UK
    J Appl Physiol (1985) 103:682-92. 2007
    ..In conclusion, a substantial proportion of the between-individual variance in relationships between PAI, accelerometry, and HR is captured with simple calibration procedures, feasible for use in epidemiological studies...
  8. ncbi Guidelines on the management of stable angina pectoris: executive summary: The Task Force on the Management of Stable Angina Pectoris of the European Society of Cardiology
    Kim Fox
    Department of Cardiology, Royal Brompton Hospital, London, UK
    Eur Heart J 27:1341-81. 2006
  9. ncbi Six-minute walk test in children and adolescents
    Ralf Geiger
    Department of Pediatrics, Clinical Division of Cardiology, Pulmology, Allergology, and Cystic Fibrosis, Innsbruck Medical University, Innsbruck, Austria
    J Pediatr 150:395-9, 399.e1-2. 2007
    ..To evaluate the 6-minute walking distance (6MWD) for healthy Caucasian children and adolescents of a population-based sample from the age of 3 to 18 years...
  10. ncbi Predictors of success and failure in pulmonary rehabilitation
    R Garrod
    School of Physiotherapy, Faculty of Health and Social Care Sciences, St George s, University of London, UK
    Eur Respir J 27:788-94. 2006
    ..Risk of drop-out is significantly greater in depressed compared with nondepressed patients...
  11. ncbi Local dynamic stability versus kinematic variability of continuous overground and treadmill walking
    J B Dingwell
    Sensory Motor Performance Program, Rehabiliation Institute of Chicago, IL 60611, USA
    J Biomech Eng 123:27-32. 2001
    ..Thus, motorized treadmills may produce misleading or erroneous results in situations where changes in neuromuscular control are likely to affect the variability and/or stability of locomotion...
  12. ncbi Heart-rate profile during exercise as a predictor of sudden death
    Xavier Jouven
    Service de cardiologie, Faculté René Descartes, Universite Paris 5, Hopital Europeen Georges Pompidou, Paris, France
    N Engl J Med 352:1951-8. 2005
    ....
  13. ncbi The use of uniaxial accelerometry for the assessment of physical-activity-related energy expenditure: a validation study against whole-body indirect calorimetry
    Hideaki Kumahara
    Laboratory of Physiology, Faculty of Medicine, University of Lausanne, Lausanne, Switzerland
    Br J Nutr 91:235-43. 2004
    ..This method is also important for assessing the diurnal profile of physical activity...
  14. ncbi Interpretation of treatment changes in 6-minute walk distance in patients with COPD
    M A Puhan
    Horten Centre, University Hospital of Zurich, Postfach Nord, CH 8091 Zurich, Switzerland
    Eur Respir J 32:637-43. 2008
    ..This corresponds to a 10% change of baseline 6-min walk distance. The low correlations of 6-min walk distance with patient-reported anchors question whether a minimal important difference exists for the 6-min walk distance...
  15. ncbi Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity
    C A Hill
    School of Sports, Exercise and Health Sciences, University of Chichester, Chichester, UK
    Amino Acids 32:225-33. 2007
    ..0%); with a further +3.2% increase at 10 wks. TWD was unchanged at 4 and 10 wks in the control subjects. The increase in TWD with supplementation followed the increase in muscle carnosine...
  16. ncbi Low cardiorespiratory fitness is a strong predictor for clustering of cardiovascular disease risk factors in children independent of country, age and sex
    Sigmund A Anderssen
    Department of Sports Medicine, Norwegian School of Sports Sciences, Oslo, Norway
    Eur J Cardiovasc Prev Rehabil 14:526-31. 2007
    ..This cross-sectional study examined the association between fitness and clustered CVD risk in children and adolescents from three European countries...
  17. ncbi The six-minute walk test in healthy children: reliability and validity
    A M Li
    Dept of Paediatrics, 6th Floor, Clinical Sciences Building, Prince of Wales Hospital, Chinese University of Hong Kong, Shatin, Hong Kong
    Eur Respir J 25:1057-60. 2005
    ..Seventy-eight subjects were recruited; however, four failed to achieve maximal effort on exercise test. The final group included 43 young females and the mean+/-sd age of the subjects was 14.2+/-1.2 yrs...
  18. pmc The validity and reliability of a novel activity monitor as a measure of walking
    C G Ryan
    School of Health and Social Care, Glasgow Caledonian University, Glasgow, Scotland, UK
    Br J Sports Med 40:779-84. 2006
    ..The accurate measurement of physical activity is crucial to understanding the relationship between physical activity and disease prevention and treatment...
  19. ncbi The 6-minute walk test as a new outcome measure in Duchenne muscular dystrophy
    Craig M McDonald
    Department of Physical Medicine and Rehabilitation, University of California Davis School of Medicine, Sacramento, California, 95817, USA
    Muscle Nerve 41:500-10. 2010
    ..A modified 6MWT is feasible and safe, documents disease-related limitations on ambulation, is reproducible, and offers a new outcome measure for DMD natural history and therapeutic trials...
  20. ncbi Effect of β-alanine plus sodium bicarbonate on high-intensity cycling capacity
    Craig Sale
    Biomedical, Life and Health Sciences Research Centre, School of Science and Technology, Nottingham Trent University, Nottingham, UK
    Med Sci Sports Exerc 43:1972-8. 2011
    ..We examined the effect of β-alanine supplementation plus sodium bicarbonate on high-intensity cycling capacity...
  21. ncbi The 6-min walk test: a quick measure of functional status in elderly adults
    Paul L Enright
    University of Arizona, USA
    Chest 123:387-98. 2003
    ..To determine the correlates of the total 6-min walk distance (6MWD) in a population sample of adults > or = 68 years old...
  22. pmc Intramyocellular lipids form an important substrate source during moderate intensity exercise in endurance-trained males in a fasted state
    Luc J C van Loon
    Nutrition Research Institute Maastricht, Maastricht University, Maastricht, The Netherlands
    J Physiol 553:611-25. 2003
    ....
  23. ncbi Updating the minimal important difference for six-minute walk distance in patients with chronic obstructive pulmonary disease
    Anne E Holland
    School of Physiotherapy, La Trobe University, Melbourne, Australia
    Arch Phys Med Rehabil 91:221-5. 2010
    ..To establish the minimal important difference (MID) for the six-minute walk distance (6MWD) in persons with chronic obstructive pulmonary disease (COPD)...
  24. ncbi Validity of simple field tests as indicators of match-related physical performance in top-level professional soccer players
    E Rampinini
    Human Performance Lab, Castellanza, Varese, Italy
    Int J Sports Med 28:228-35. 2007
    ..05). In conclusion, this study gives empirical support to the construct validity of RSA and incremental running tests as measures of match-related physical performance in top-level professional soccer players...
  25. ncbi The minimal important difference of exercise tests in severe COPD
    M A Puhan
    Dept of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD 21205, USA
    Eur Respir J 37:784-90. 2011
    ..0-2.4 W), 3.2 W (95% CI 3.0-3.4 W), 3.2 W (95% CI 3.0-3.4 W) and 3.3 W (95% CI 3.0-3.5 W), while distribution-based estimates were 5.3 and 5.5 W. We suggest a MID of 26 ± 2 m for 6MWD and 4 ± 1 W for MCEC for patients with severe COPD...
  26. pmc Estimating absolute and relative physical activity intensity across age via accelerometry in adults
    Nora E Miller
    Dept of Human Movement Sciences, University of Wisconsin Milwaukee, USA
    J Aging Phys Act 18:158-70. 2010
    ..absolute terms across age revealed substantial differences in PAI ACC count ranges. Further work is warranted to increase the applicability ofACC use relative to PAI differences associated with physiological changes with age...
  27. ncbi Detection of silent myocardial ischemia in asymptomatic diabetic subjects: the DIAD study
    Frans J Th Wackers
    Section of Cardiovascular Medicine, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut 06520, USA
    Diabetes Care 27:1954-61. 2004
    ..To assess the prevalence and clinical predictors of silent myocardial ischemia in asymptomatic patients with type 2 diabetes and to test the effectiveness of current American Diabetes Association screening guidelines...
  28. pmc Cardiac outcomes after screening for asymptomatic coronary artery disease in patients with type 2 diabetes: the DIAD study: a randomized controlled trial
    Lawrence H Young
    Yale University School of Medicine, Section of Cardiovascular Medicine, Department of Internal Medicine, New Haven, CT 06520, USA
    JAMA 301:1547-55. 2009
    ..Coronary artery disease (CAD) is the major cause of mortality and morbidity in patients with type 2 diabetes. But the utility of screening patients with type 2 diabetes for asymptomatic CAD is controversial...
  29. pmc The influence of gait speed on local dynamic stability of walking
    Scott A England
    Musculoskeletal Biomechanics Laboratories, Department of Engineering Science and Mechanics, School of Biomedical Engineering and Science, Virginia Polytechnic Institute and State University, 219 Norris Hall 0219, Blacksburg, VA 24061, United States
    Gait Posture 25:172-8. 2007
    ..This suggests that slower walking velocities lead to increases in stability. These results may reveal more detailed information on the behavior of the neuro-controller than variability-based analyses alone...
  30. ncbi North Star Ambulatory Assessment, 6-minute walk test and timed items in ambulant boys with Duchenne muscular dystrophy
    Elena Mazzone
    Department of Paediatric Neurology, Catholic University, Rome, Italy
    Neuromuscul Disord 20:712-6. 2010
    ..These findings suggest that a combination of these outcome measures can be effectively used in ambulant DMD boys and will provide information on different aspects of motor function, that may not be captured using a single measure...
  31. ncbi Assessment of survival in patients with primary pulmonary hypertension: importance of cardiopulmonary exercise testing
    Roland Wensel
    Department of Cardiothoracic Surgery, Deutsches Herzzentrum Berlin, Germany
    Circulation 106:319-24. 2002
    ..Prognostic assessment is an important factor in determining medical treatment and lung transplantation. Whether cardiopulmonary exercise testing data predict survival has not been reported previously...
  32. ncbi Determining the minimal clinically important difference for the six-minute walk test and the 200-meter fast-walk test during cardiac rehabilitation program in coronary artery disease patients after acute coronary syndrome
    Vincent Gremeaux
    Pôle Rééducation Réadaptation, Centre Hospitalier Universitaire de Dijon, France
    Arch Phys Med Rehabil 92:611-9. 2011
    ..To estimate the minimal clinically important difference (MCID) for the 6-minute walk test (6MWT) and the 200-m fast-walk test (FWT) in patients with coronary artery disease (CAD) during a cardiac rehabilitation program...
  33. ncbi Exercise pathophysiology in patients with primary pulmonary hypertension
    X G Sun
    Department of Medicine, Harbor-UCLA Medical Center, Torrance, California, USA
    Circulation 104:429-35. 2001
    ..CONCLUSIONS: Patients with PPH can safely undergo noninvasive cycle ergometer CPET to their maximal tolerance. The CPET abnormalities were consistent and characteristic and correlated well with NYHA class...
  34. ncbi End-tidal PCO2 abnormality and exercise limitation in patients with primary pulmonary hypertension
    Yuji Yasunobu
    Department of Medicine, Los Angeles Biomedical Research Institute, Harbor UCLA Medical Center, Torrance, CA 90509 2910, USA
    Chest 127:1637-46. 2005
    ..Our aim was to determine the size of the reduction in end-tidal Pco(2) (Petco(2)) as a reflection of the abnormality in ventilatory efficiency and ventilatory drive in PPH patients...
  35. ncbi Assessing cardiorespiratory fitness without performing exercise testing
    Radim Jurca
    The Cooper Institute, Dallas, TX 75230, USA
    Am J Prev Med 29:185-93. 2005
    ..The purpose of this study is to extend previous work on a non-exercise test model to predict CRF from health indicators that are easily obtained.
  36. pmc Kinematic variability, fractal dynamics and local dynamic stability of treadmill walking
    Philippe Terrier
    IRR, Institut de Recherche en Réadaptation, Sion, Switzerland
    J Neuroeng Rehabil 8:12. 2011
    ..Classical (Standard Deviation, SD) and non-linear (fractal dynamics, local dynamic stability) methods were used. In addition, the correlations between the different variability indexes were analyzed...
  37. ncbi Exercise training associated with diet improves heart rate recovery and cardiac autonomic nervous system activity in obese children
    D M Prado
    Medical School, Department of Endocrinology, University of Sao Paulo, Brazil
    Int J Sports Med 31:860-5. 2010
    ..that in obese children: 1) hypocaloric diet (D) improves both heart rate recovery at 1 min (Δ HRR1) cfter an exercise test, and cardiac autonomic nervous system activity (CANSA) in obese children; 2) Diet and exercise training (DET) ..
  38. ncbi Exercise anaerobic threshold and ventilatory efficiency identify heart failure patients for high risk of early death
    Anselm K Gitt
    Herzzentrum Ludwigshafen, Department of Cardiology, Ludwigshafen, Germany
    Circulation 106:3079-84. 2002
    ..Thus, we compared these parameters with peak VO2 in identifying patients with CHF at increased risk for death within 6 months after evaluation...
  39. ncbi A comparison between three rating scales for perceived exertion and two different work tests
    E Borg
    Department of Psychology, Stockholm University, Stockholm, Sweden
    Scand J Med Sci Sports 16:57-69. 2006
    ..The obtained deviations from what has previously been obtained for work of longer duration (4-6 min) points to a need for standardization of work-test protocols and to the advantage of using CR scales...
  40. pmc Prognostic value of functional performance for mortality in patients with peripheral artery disease
    Mary M McDermott
    Department of Medicine, Northwestern University s Feinberg School of Medicine, Chicago, Illinois, USA
    J Am Coll Cardiol 51:1482-9. 2008
    ..Among persons with lower extremity peripheral artery disease (PAD), we determined whether objective measures of walking performance predict mortality independently of the ankle brachial index (ABI)...
  41. ncbi Endurance training and detraining in mitochondrial myopathies due to single large-scale mtDNA deletions
    Tanja Taivassalo
    Department of Kinesiology, McGill University, Montreal, Quebec, Canada
    Brain 129:3391-401. 2006
    ..The effects of detraining clearly implicate physical inactivity as an important mechanism in reducing exercise capacity and quality of life in patients with mitochondrial myopathy...
  42. ncbi Ability of exercise testing to predict cardiovascular and all-cause death in asymptomatic women: a 20-year follow-up of the lipid research clinics prevalence study
    Samia Mora
    Ciccarone Preventive Cardiology Center, Department of Medicine, Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    JAMA 290:1600-7. 2003
    ..The value of exercise testing in women has been questioned...
  43. pmc Outcome measures in chronic obstructive pulmonary disease (COPD): strengths and limitations
    Thomas Glaab
    Pulmonary Department, University Hospital, Johannes Gutenberg University, Mainz, Germany
    Respir Res 11:79. 2010
    ....
  44. ncbi Post-concurrent exercise hemodynamics and cardiac autonomic modulation
    Luiz Teixeira
    Exercise Hemodynamic Laboratory, School of Physical Education and Sport, University of Sao Paulo, Sao Paulo, Brazil
    Eur J Appl Physiol 111:2069-78. 2011
    ..2 ± 0.8, P < 0.05). In conclusion, the association of aerobic and resistance exercises in the same training session did not potentiate post-exercise hypotension, and increased cardiac sympathetic activation during the recovery period...
  45. ncbi A longitudinal study of the development of low back pain in an industrial population
    J M Stevenson
    Faculty of Kinesiology, University of New Brunswick, Fredericton, New Brunswick, Canada
    Spine (Phila Pa 1976) 26:1370-7. 2001
    ..This is a longitudinal study in which industrial workers without chronic low back pain (LBP) were initially assessed with a comprehensive test battery and surveyed every 6 months thereafter for 2 years...
  46. ncbi Recommendations on the use of exercise testing in clinical practice
    P Palange
    Servizio di Fisiopatologia Respiratoria, Dipartimento di Medicina Clinica, University of Rome La Sapienza, Rome, Italy
    Eur Respir J 29:185-209. 2007
    ..intolerance be sought?"; 2) "Which particular form of test should be asked for?"; and 3) "What cluster of variables should be selected when evaluating prognosis for a particular disease or the effect of a particular intervention?"..
  47. ncbi Heart rate recovery: validation and methodologic issues
    K Shetler
    Division of Cardiovascular Medicine, Stanford University Medical Center and the Veterans Affairs Palo Alto Health Care System, Palo Alto, California 94304, USA
    J Am Coll Cardiol 38:1980-7. 2001
    ..CONCLUSIONS: Heart rate at 1 or 2 min of recovery has been validated as a prognostic measurement and should be recorded as part of all treadmill tests. This new measurement does not replace, but is supplemental to, established scores...
  48. ncbi Exercise training decreases ventilatory requirements and exercise-induced hyperinflation at submaximal intensities in patients with COPD
    Janos Porszasz
    Division of Respiratory and Critical Care Physiology and Medicine, Los Angeles Biomedical Research Institute at Harbor UCLA Medical Center, Rehabilitation Clinical Trials Center, Torrance, CA 90502, USA
    Chest 128:2025-34. 2005
    ..We hypothesized that endurance exercise training would reduce the degree of hyperinflation for a given level of exercise and thereby improve submaximal exercise endurance...
  49. doi Interstitial lung disease guideline: the British Thoracic Society in collaboration with the Thoracic Society of Australia and New Zealand and the Irish Thoracic Society
    B Bradley
    Royal Infirmary Edinburgh, Little France Crescent, Edinburgh EH16 4SA, UK
    Thorax 63:v1-58. 2008
  50. ncbi Stress protocols and tracers
    Milena J Henzlova
    J Nucl Cardiol 13:e80-90. 2006
  51. ncbi Effects of tiotropium on lung hyperinflation, dyspnoea and exercise tolerance in COPD
    D E O'Donnell
    Respiratory Investigation Unit, Dept of Medicine, Queen s University, Kingston, Ontario, Canada
    Eur Respir J 23:832-40. 2004
    ..Resultant increases in inspiratory capacity permitted greater expansion of tidal volume and contributed to improvements in both exertional dyspnoea and exercise endurance...
  52. ncbi A cardiopulmonary exercise testing score for predicting outcomes in patients with heart failure
    Jonathan Myers
    Veterans Affairs Palo Alto Health Care System, Palo Alto, CA 94304, USA
    Am Heart J 156:1177-83. 2008
    The aim of this study is to evaluate the predictive accuracy of a cardiopulmonary exercise test (CPX) score.
  53. ncbi Treadmill exercise rehabilitation improves ambulatory function and cardiovascular fitness in patients with chronic stroke: a randomized, controlled trial
    Richard F Macko
    Veterans Affairs Medical Center Geriatrics Research, Education, and Clinical Center, Department of Neurology, University of Maryland School of Medicine, Baltimore, MD, USA
    Stroke 36:2206-11. 2005
    ..We investigated whether treadmill aerobic training (T-AEX) is more effective than conventional rehabilitation to improve ambulatory function and cardiovascular fitness in patients with chronic stroke...
  54. ncbi Locomotor adaptation to resistance during treadmill training transfers to overground walking in human SCI
    Sheng Che Yen
    Sensory Motor Performance Program, Rehabilitation Institute of Chicago, 345 East Superior Street, Room 1406, Chicago, IL 60611, USA
    Exp Brain Res 216:473-82. 2012
    ..Such a paradigm may be useful as an adjunct approach to improve the locomotor function in patients with incomplete SCI...
  55. ncbi Effect of combined β-alanine and sodium bicarbonate supplementation on cycling performance
    Phillip M Bellinger
    School of Human Life Sciences, University of Tasmania, Launceston, Tasmania, Australia
    Med Sci Sports Exerc 44:1545-51. 2012
    ....
  56. pmc Flecainide therapy reduces exercise-induced ventricular arrhythmias in patients with catecholaminergic polymorphic ventricular tachycardia
    Christian van der Werf
    Department of Cardiology, Heart Failure Research Center, Academic Medical Center, Amsterdam, The Netherlands
    J Am Coll Cardiol 57:2244-54. 2011
    ..This study evaluated the efficacy and safety of flecainide in addition to conventional drug therapy in patients with catecholaminergic polymorphic ventricular tachycardia (CPVT)...
  57. ncbi Moving towards meaningful measurement: Rasch analysis of the North Star Ambulatory Assessment in Duchenne muscular dystrophy
    Anna Mayhew
    Institute of Human Genetics, International Centre for Life, Newcastle University, Newcastle upon Tyne, UK
    Dev Med Child Neurol 53:535-42. 2011
    ..In this study, we used Rasch analysis to test its suitability in these roles as a measurement instrument...
  58. ncbi Postexercise carbohydrate-protein supplementation improves subsequent exercise performance and intracellular signaling for protein synthesis
    Lisa Ferguson-Stegall
    Exercise Physiology and Metabolism Laboratory, Department of Kinesiology, University of Texas at Austin, Austin, Texas, USA
    J Strength Cond Res 25:1210-24. 2011
    ..7 vs. 69.2 ± 5.5%, p ≤ 0.05). These results indicate that postexercise CM supplementation can improve subsequent exercise performance and provide a greater intracellular signaling stimulus for PRO synthesis compared to CHO and placebo...
  59. ncbi Six-year follow-up of a randomised controlled trial examining hospital versus home-based exercise training after coronary artery bypass graft surgery
    Kelly M Smith
    Department of Medicine, University of Illinois College of Medicine at Chicago, Section of Health Promotion Research, Chicago, Illinois, USA
    Heart 97:1169-74. 2011
    ..To compare the long-term effectiveness of hospital versus telephone-monitored home-based exercise training during cardiac rehabilitation (CR) on exercise capacity and habitual physical activity...
  60. ncbi Exercise limitation, exercise testing and exercise recommendations in sickle cell anemia
    Philippe Connes
    Laboratory ACTES, Department of Physiology, University of the French West Indies, Pointe a Pitre, Guadeloupe, French West Indies
    Clin Hemorheol Microcirc 49:151-63. 2011
    ..have investigated the cardiorespiratory responses of patients with SCA during either symptom-limited maximal exercise test on cyclo-ergometer or during a six minute walk test...
  61. ncbi Low-level laser therapy (LLLT) in human progressive-intensity running: effects on exercise performance, skeletal muscle status, and oxidative stress
    Thiago De Marchi
    Institute of Biotechnology, University of Caxias do Sul, Caxias do Sul, RS, Brazil
    Lasers Med Sci 27:231-6. 2012
    ....
  62. ncbi Reference equations for the performance of healthy adults on field walking tests
    Victor Zuniga Dourado
    Universidade Federal de Sao Paulo, Santos, SP, Brasil
    J Bras Pneumol 37:607-14. 2011
    ..To develop regression equations for predicting six-minute and incremental shuttle walk distances (6MWD and ISWD, respectively), based on demographic characteristics, anthropometric variables, and grip strength...
  63. ncbi Comparison of the 2-, 6-, and 12-minute walk tests in patients with stroke
    Marc Kosak
    Burke Rehabilitation Hospital, White Plains, NY 10605, USA
    J Rehabil Res Dev 42:103-7. 2005
    ..The SRM statistic indicates that the 12-minute walk test is the most responsive to change...
  64. ncbi Exercise testing to estimate survival in pulmonary hypertension
    Herman Groepenhoff
    Institute for Cardiovascular Research and Department of Pulmonology, VU University Medical Center, Amsterdam, The Netherlands
    Med Sci Sports Exerc 40:1725-32. 2008
    ..The peak oxygen consumption (V O2peak) measured during a cardiopulmonary exercise test (CPET) also relates to survival in PH, and it is unknown how the prognostic information from measurements of ..
  65. pmc Cardiorespiratory fitness and physical activity in Luo, Kamba, and Maasai of rural Kenya
    D L Christensen
    Department of International Health, University of Copenhagen, Copenhagen, Denmark
    Am J Hum Biol 24:723-9. 2012
    ..The aim of this study was to describe objectively measured PAEE and CRF in different ethnic populations of rural Kenya...
  66. ncbi Assessing disability in morbidly obese individuals: the Italian Society of Obesity test for obesity-related disabilities
    Lorenzo M Donini
    Department of Medical Physiopathology Food Science Section Sapienza University of Rome, Italy
    Disabil Rehabil 33:2509-18. 2011
    ..To validate a new obesity-specific disability assessment test: the Obesity-related Disability test (Test SIO Disabilità Obesità Correlata, TSD-OC)...
  67. ncbi Exercise intolerance in adult congenital heart disease: comparative severity, correlates, and prognostic implication
    Gerhard Paul Diller
    Adult Congenital Heart Program, Department of Cardiology, Royal Brompton Hospital, London, UK
    Circulation 112:828-35. 2005
    ....
  68. ncbi Evaluation of the six-minute walk in multiple sclerosis subjects and healthy controls
    Myla D Goldman
    Department of Neurology, University of Virginia, Charlottesville, VA 22908, USA
    Mult Scler 14:383-90. 2008
    ..To assess the correlation of 6MW to subjective measures of fatigue, health status and ambulation using the modified fatigue impact scale (MFIS), short form-36 Health Questionnaire physical component score and MS walking scale (MSWS)...
  69. ncbi Effect of beta-alanine supplementation on repeated sprint performance during the Loughborough Intermittent Shuttle Test
    Bryan Saunders
    Sport, Health and Performance Enhancement SHAPE Research Group, School of Science and Technology, Nottingham Trent University, Clifton Lane, Nottingham, NG11 8NS, UK
    Amino Acids 43:39-47. 2012
    ..Neither group showed a performance decrement prior to supplementation, which might have masked any benefit from increased muscle buffering capacity due to β-alanine supplementation...
  70. ncbi A qualitative systematic overview of the measurement properties of functional walk tests used in the cardiorespiratory domain
    S Solway
    Graduate Department of Rehabilitation Science, University of Toronto, Toronto, Ontario, Canada
    Chest 119:256-70. 2001
    ....
  71. ncbi Physiological and biological factors associated with a 24 h treadmill ultra-marathon performance
    G Y Millet
    Exercise Physiology Laboratory, Jean Monnet University, Saint Etienne, France
    Scand J Med Sci Sports 21:54-61. 2011
    ..The ability to maintain a high %VO(2max) over a 24TR is another factor associated with performance and is mainly related to RE and high mitochondrial oxidative capacity in the vastus lateralis...
  72. ncbi Optimal medical therapy with or without percutaneous coronary intervention to reduce ischemic burden: results from the Clinical Outcomes Utilizing Revascularization and Aggressive Drug Evaluation (COURAGE) trial nuclear substudy
    Leslee J Shaw
    Emory University School of Medicine, Atlanta, GA 30306, USA
    Circulation 117:1283-91. 2008
    ....
  73. ncbi Normal values for cardiopulmonary exercise testing in children
    Arend Derk Jan Ten Harkel
    Department of Pediatric Cardiology, Erasmus MC Sophia, Rotterdam, The Netherlands
    Eur J Cardiovasc Prev Rehabil 18:48-54. 2011
    ..A reference set of data of normal values of newly developed cardiopulmonary parameters of exercise testing in an 8-18-year-old population is lacking...
  74. ncbi Reproducibility of maximal exercise test data in the HERITAGE family study
    J S Skinner
    Indiana University, Bloomington, USA
    Med Sci Sports Exerc 31:1623-8. 1999
    ..The reproducibility of responses to maximal cycle ergometer testing was determined using data from the HERITAGE Family study at four Clinical Centers in the United States and Canada...
  75. ncbi Effects of body mass index and tilt angle on output of two wearable activity monitors
    Yuri Feito
    Department of Kinesiology, Recreation, and Sport Studies, The University of Tennessee, Knoxville, TN, USA
    Med Sci Sports Exerc 43:861-6. 2011
    ..However, output from these devices has not been compared among normal, overweight, and obese individuals...
  76. ncbi Near-infrared spectroscopy assessment following exercise training in patients with intermittent claudication and in untrained healthy participants
    Fabio Manfredini
    Vascular Diseases Center, University of Ferrara, Italy
    Vasc Endovascular Surg 46:315-24. 2012
    ..The assessment of NIRS parameters, that were found stable without training in healthy and modified in PAD only following structured training, might outline the local exercise-induced adaptations...
  77. ncbi Measures of exercise capacity in adults with congenital heart disease
    Roselien Buys
    Research Centre for Cardiovascular and Respiratory Rehabilitation, Department of Rehabilitation Sciences, Katholieke Universiteit Leuven, Tervuursevest 101 bus 1501, 3001 Heverlee, Belgium
    Int J Cardiol 153:26-30. 2011
    ..Our aim was to evaluate the maximal character of exercise tests, and to investigate submaximal measures of exercise capacity...
  78. pmc A comprehensive evaluation of commonly used accelerometer energy expenditure and MET prediction equations
    Kate Lyden
    Department of Kinesiology, University of Massachusetts, Amherst, 30 Eastman Lane, Amherst, MA 01003, USA
    Eur J Appl Physiol 111:187-201. 2011
    ..99 METs, vigorous ≥ 6 METs). Current prediction techniques have many limitations when translating accelerometer counts to EE...
  79. pmc Oxygen cost of treadmill and over-ground walking in mildly disabled persons with multiple sclerosis
    Robert W Motl
    Department of Kinesiology and Community Health, University of Illinois at Urbana Champaign, 350 Freer Hall, 906 South Goodwin Ave, Urbana, IL 61801, USA
    Neurol Sci 32:255-62. 2011
    ..We provide evidence that the O(2) cost of walking is an indicator of walking dysfunction in mildly disabled persons with MS and should be considered in clinical research and practice...
  80. ncbi Progressive right ventricular dysfunction in patients with pulmonary arterial hypertension responding to therapy
    Marielle C van de Veerdonk
    Department of Pulmonary Diseases, VU University Medical Center, Amsterdam, The Netherlands
    J Am Coll Cardiol 58:2511-9. 2011
    ....
  81. ncbi Cardiopulmonary exercise testing as a screening test for perioperative management of major surgery in the elderly
    P Older
    Western Hospital, Footscray, Victoria, Australia
    Chest 116:355-62. 1999
    ..To develop an integrated strategy for the identification and subsequent management of high-risk patients in order to reduce both morbidity and mortality...
  82. ncbi Measurement of symptoms, lung hyperinflation, and endurance during exercise in chronic obstructive pulmonary disease
    D E O'Donnell
    Respiratory Investigation Unit, Departments of Medicine, and Community Health and Epidemiology, Queen s University, Kingston, Ontario, Canada
    Am J Respir Crit Care Med 158:1557-65. 1998
    ..35, p < 0.001). We concluded that Borg dyspnea ratings, and measurements of IC and endurance time during submaximal cycle exercise testing are highly reproducible and responsive to change in severe COPD...
  83. ncbi Aerobic and anaerobic exercise capacity in children with juvenile idiopathic arthritis
    M van Brussel
    University Hospital for Children and Youth Wilhelmina Kinderziekenhuis, University Medical Center Utrecht, Utrecht, The Netherlands
    Arthritis Rheum 57:891-7. 2007
    ....
  84. ncbi Assessment of physical activity with the Computer Science and Applications, Inc., accelerometer: laboratory versus field validation
    J F Nichols
    Department of Exercise and Nutritional Sciences, San Diego State University, USA
    Res Q Exerc Sport 71:36-43. 2000
    ..We conclude that the CSA can be used to quantify walking and jogging outdoors on level ground; however, laboratory equations may not be appropriate for use in field settings, particularly for light and vigorous activity...
  85. ncbi Changes in running kinematics, kinetics, and spring-mass behavior over a 24-h run
    Jean Benoit Morin
    Universite de Lyon, Saint Etienne, France
    Med Sci Sports Exerc 43:829-36. 2011
    ..This study investigated the changes in running mechanics and spring-mass behavior over a 24-h treadmill run (24TR)...
  86. ncbi Cardiorespiratory fitness, adiposity, and all-cause mortality in women
    Stephen W Farrell
    The Cooper Institute, Dallas, TX 75230, USA
    Med Sci Sports Exerc 42:2006-12. 2010
    ..To determine the prospective associations among cardiorespiratory fitness (CRF), different measures of adiposity, and all-cause mortality in women...
  87. ncbi Evaluation of pretest and exercise test scores to assess all-cause mortality in unselected patients presenting for exercise testing with symptoms of suspected coronary artery disease
    Anthony P Morise
    Section of Cardiology, Department of Medicine, West Virginia University School of Medicine, Morgantown, WV 26506, USA
    J Am Coll Cardiol 42:842-50. 2003
    ..To determine how well recently developed multivariables scores assess for all-cause mortality in patients with suspected coronary disease presenting for exercise electrocardiography (ExECG)...
  88. ncbi Role of beta-alanine supplementation on muscle carnosine and exercise performance
    Guilherme Giannini Artioli
    Laboratory of Applied Nutrition and Metabolism, School of Physical Education and Sports, University of Sao Paulo, Sao Paulo, Brazil
    Med Sci Sports Exerc 42:1162-73. 2010
    ..No important side effect was related to the use of this amino acid so far. In conclusion, beta-alanine supplementation seems to be a safe nutritional strategy capable of improving high-intensity anaerobic performance...
  89. ncbi Improvements in cognitive function following cardiac rehabilitation for older adults with cardiovascular disease
    Kelly M Stanek
    Department of Psychology, Kent State University, Kent, Ohio 44242, USA
    Int J Neurosci 121:86-93. 2011
    ....
  90. ncbi Effect of 830 nm low-level laser therapy in exercise-induced skeletal muscle fatigue in humans
    Ernesto Cesar Pinto Leal Junior
    Laboratory of Human Movement LMH, University of Caxias do Sul, Rua Francisco Getúlio Vargas, 1130, Caxias do Sul, 95070 560, Rio Grande do Sul, Brazil
    Lasers Med Sci 24:425-31. 2009
    ..We concluded that 830 nm LLLT can delay the onset of skeletal muscle fatigue in high-intensity exercises, in spite of increased blood lactate levels...
  91. ncbi High-sensitive troponin T: a novel biomarker for prognosis and disease severity in patients with pulmonary arterial hypertension
    Arthur Filusch
    Department of Cardiology, Angiology and Respiratory Medicine, University Medical Center, Im Neuenheimer Feld 410, D 69120 Heidelberg, Germany
    Clin Sci (Lond) 119:207-13. 2010
    ..In conclusion, in PAH patients, the novel biomarker hsTnT is associated with death and advanced WHO functional class, and is related to systolic right ventricular dysfunction and an impaired 6-min walk distance...
  92. ncbi Exercise induces behavioral recovery and attenuates neurochemical deficits in rodent models of Parkinson's disease
    J L Tillerson
    Institute for Neuroscience, University of Texas at Austin, Austin, TX, 78712, USA
    Neuroscience 119:899-911. 2003
    ..These results demonstrate that exercise following nigrostriatal damage ameliorates related motor symptoms and neurochemical deficits in rodent models of PD...
  93. ncbi Is physical activity or aerobic power more influential on reducing cardiovascular disease risk factors?
    R G McMurray
    Center for Health Promotions Disease Prevention, University of North Carolina, Chapel Hill, USA
    Med Sci Sports Exerc 30:1521-9. 1998
    ..The study also determined how increased VO2max and increased PA levels influence CVD risk factors of 576 low-fit adults (VO2max < 30 mL.kg-1.min-1)...
  94. ncbi Physiological responses to the 6-min walk test in patients with chronic obstructive pulmonary disease
    T Troosters
    Faculty of Physical Education and Physiotherapy, Respiratory Muscle Unit, Katholieke Universiteit Leuven, Belgium
    Eur Respir J 20:564-9. 2002
    ..Since the oxygen uptake plateau reflects the integrated response of the system, it may explain the high prognostic value of the 6-min walking test...
  95. ncbi Gas exchange detection of exercise-induced right-to-left shunt in patients with primary pulmonary hypertension
    Xing Guo Sun
    Department of Medicine, Harbor UCLA Medical Center, Torrance, Calif 90509 2910, USA
    Circulation 105:54-60. 2002
    ..This article first hypothesizes and then describes unique changes in gas exchange when right-to-left exercise-induced shunting (EIS) occurs...
  96. ncbi Transcutaneous oxygen pressure measurements on the buttocks during exercise to detect proximal arterial ischemia: comparison with arteriography
    Pierre Abraham
    Department of Vascular Studies, University Hospital of Angers, France
    Circulation 107:1896-900. 2003
    ..We sought to identify whether transcutaneous oxygen tension (tcPo2) measurements could be used to noninvasively detect lesions in the arterial network supplying blood flow to the hypogastric circulation...
  97. ncbi Validity of the Actical accelerometer step-count function
    Dale W Esliger
    College of Kinesiology, University of Saskatchewan, Saskatoon, Canada
    Med Sci Sports Exerc 39:1200-4. 2007
    ..To assess the validity of the new Actical accelerometer step count function...
  98. ncbi Effect of time of day on aerobic contribution to the 30-s Wingate test performance
    Nizar Souissi
    Research Unit, Evaluation, Sport, Health, National Centre of Medicine and Science in Sport, Route de l Aéroport, Sfax 3000, Tunisia
    Chronobiol Int 24:739-48. 2007
    ..Altogether, these results indicate that the time-of-day effect on performances during the Wingate test is mainly due to better aerobic participation in energy production during the test in the afternoon than in the morning...
  99. ncbi Heliox improves oxygen delivery and utilization during dynamic exercise in patients with chronic obstructive pulmonary disease
    Gaspar R Chiappa
    Pulmonary Function and Clinical Exercise Physiology Unit SEFICE, Division of Respiratory Diseases, Department of Medicine, Federal University of Sao Paulo UNIFESP, Sao Paulo, Brazil
    Am J Respir Crit Care Med 179:1004-10. 2009
    ..It remains to be determined whether part of these beneficial effects could be ascribed to increased O(2) delivery (O(2)DEL) to locomotor muscles...
  100. ncbi Effects of waking time and breakfast intake prior to evaluation of physical performance in the early morning
    Clement Bougard
    Universite de Caen, EA3917, UFR STAPS, Caen, France
    Chronobiol Int 26:307-23. 2009
    ..Consequently, we advise researchers to take care in experimental design and to at least standardize the time of awakening and consumption of breakfast...
  101. pmc Accelerometer output and MET values of common physical activities
    Sarah L Kozey
    Department of Kinesiology, University of Massachusetts, 30 Eastman Lane, Amherst, MA 01003, USA
    Med Sci Sports Exerc 42:1776-84. 2010
    ....

Research Grants65

  1. Dietary Nitrate to Augment Exercise Training Benefits in DM+PAD
    Jason David Allen; Fiscal Year: 2013
    ..Specific Aim 1: To determine group differences in the change in COT, PWT and VO2peak during a maximal graded exercise test, following 12 weeks of supervised exercise training...
  2. Diagnostic Utility of mtDNA Content and Exercise Challenge in Veterans with GWI
    MICHAEL JOSEPH FALVO; Fiscal Year: 2013
    ..CFS) - yet recent data suggests that these mixed results are accounted for by the limitation of a single exercise test which fails to consider the post-exertional malaise period characteristic to those with GWI and CFS...
  3. Myostatin Regulation of Skeletal Muscle Energy Metabolism
    SUZANNE PORSZASZ-REISZ; Fiscal Year: 2013
    ..To determine the role of Mst in muscle structure, contractility and physical performance using exercise test model: Outcomes will include: force-velocity relationship, maximal exercise tolerance as measured by VO2max, ..
  4. Influence of physical activity and weight loss on brain plasticity
    Kirk I Erickson; Fiscal Year: 2013
    ..and body composition using dual-energy X-ray absorptiometry, cardiorespiratory fitness using a graded exercise test, accelerometry measured physical activity, and energy intake...
  5. Increased Plasma Nitrite, Tissue Oxygenation and Functional Changes in PAD
    Jason David Allen; Fiscal Year: 2013
    ..Specific Aim 1b: In these subjects, determine differences in COT, PWT and VO2peak during a graded exercise test, between randomization to 8 weeks of SET or PET...
  6. Heart Camp: Promoting Adherence to Exercise in Patients with Heart Failure
    Bunny Pozehl; Fiscal Year: 2013
    ..All subjects will receive a cardiopulmonary exercise test and 9 supervised exercise training sessions during a 3 week run-in period prior to randomization...
  7. Ph 2 Study of Triheptanoin for Tx of Long-Chain Fatty Acid Oxidation Disorder
    Melanie B Gillingham; Fiscal Year: 2013
    ..effects of supplement treatment on total energy expenditure, the response to a moderate intensity treadmill exercise test, cardiac function and long-chain fatty acid oxidation capacity...
  8. Affective Responses to High-Intensity Interval Training
    Marcus Kilpatrick; Fiscal Year: 2013
    ..One hundred sedentary, overweight adults will complete a maximal exercise test and four subsequent exercise trials: two continuous (moderate intensity for 30 minutes and vigorous intensity ..
  9. Exercise and Quality of Life in Severely Burned Children
    Oscar E Suman; Fiscal Year: 2013
    ..Primary outcomes are peak aerobic capacity assessed with a.cardiopulmonary exercise test;muscle strength, using leg dynamometry, muscle mass assessed usingidual X-ray absorptiometry, and net protein ..
  10. HEART RATE RECOVERY AND MORTALITY
    Michael Lauer; Fiscal Year: 2002
    ..overall aim of this project is to use heart-rate recovery to substantially improve the prognostic value of the exercise test. The specific aims of this project are: 1) Derive biologically meaningful mathematical models of heart-rate ..
  11. QUANTITATIVE VENTRICULOGRAPHY USING DUAL-ENERGY DSA
    MICHAEL VAN LYSEL; Fiscal Year: 1992
    ..This exercise test will be utilized to assess the functional significance of coronary stenoses at the time of cardiac ..
  12. PAIN AND BETA-ENDORPHIN RESPONSES IN MEN AND WOMEN
    David Sheps; Fiscal Year: 2001
    ..200 subjects will be assigned to one of two conditions: control and imagery task. Subjects will undergo an exercise test and forearm ischemia test in random order...
  13. IMPACT OF PHYSICAL FITNESS AND EXERCISE ON HEALTH
    Steven Blair; Fiscal Year: 2001
    ..sample, for each member of which there is an objective measure of cardiorespiratory fitness from a maximal exercise test. In addition, the database includes demographic, behavioral, and clinical data from the examination, health ..
  14. EXERCISE ANTIOXIDANTS & OXIDATIVE STRESS IN THE ELDERLY
    JAMES JESSUP; Fiscal Year: 2000
    ..The following baseline measures will be obtained: 1. A monitored, sub-maximal graded exercise test to determine their level of aerobic fitness; 2...
  15. MASSAGE THERAPY FOR PATIENTS WITH HIV-1
    Thomas Birk; Fiscal Year: 1993
    ..All subjects will undergo prescreening cardiopulmonary problems. The pre-testing will include a Graded Exercise test with electrocardiogram (ECG), oxygen uptake monitoring and blood draw for determination of CD4 levels and ..
  16. EXERCISE INDUCED CHANGES IN HPA ACTIVITY IN FIBROMYALGIA
    Patricia Deuster; Fiscal Year: 2003
    ..in hypothalamic drive as evidenced by augmented adrenocorticotropin (ACTH) responses to a standardized exercise test (SET); (2) An increase in tonic and stimulated hypothalamic drive as evidenced by augmented ACTH responses ..
  17. Mentored Patient-Oriented Research Career Development Award
    Ruey Kang Chang; Fiscal Year: 2006
    ..muscle volume by magnetic resonance imaging (MRI), echocardiogram, pulmonary function test, cardiopulmonary exercise test, catecholamine and cytokine tumor necrosis factor (TNF)-alpha, IL-1beta, and IL-6 levels at rest and during ..
  18. IMMUNOSUPPRESSIVE THERAPY FOR BIOPSY-PROVEN MYOCARDITIS
    Jay Mason; Fiscal Year: 1991
    ..biopsy, right heart hemodynamic study, radionuclide angiogram, 2-dimensional echocardiogram, treadmill exercise test, holter monitoring study and symptom assessment...
  19. IMPACT OF PHYSICAL FITNESS AND EXERCISE ON HEALTH
    Steven Blair; Fiscal Year: 2005
    ..An important strength of the study is that there is an objective measure of CRF from a maximal exercise test for each individual in this cohort...
  20. THROMBOLYSIS IN MI (TIMI) II FOLLOW-UP
    Genell Knatterud; Fiscal Year: 1991
    ..all patients enrolled, with telephone contacts at three and six months and an examination including treadmill exercise test at one year; (2) maintain annual follow-up of all patients for a minimum of three years; (3) continue the ..
  21. Sleep and Cytokines in Chronic Fatigue Syndrome
    Benjamin Natelson; Fiscal Year: 2003
    ..Finally, we will repeat this entire protocol after a day in which subjects perform a maximal exercise test because of the well-known exacerbation of CFS by exertion...
  22. UREASE AND DEAMINASES IN CHEMISTRY AND MEDICINE
    William Fishbein; Fiscal Year: 1980
    ..Clinical diagnosis will be evaluated using the lactate/ammonia exercise test, and, if feasible, by small-needle aspiration biopsy...
  23. Exercise and Children with ADHD
    ANTHONY MAHON; Fiscal Year: 2003
    ..to familiarize the subjects with the psychometric assessment and exercise testing procedures, and a graded exercise test to determine maximal aerobic work rate...
  24. POSITRON TOMOGRAPHY EXERCISE-INDUCED CARDIAC ISCHEMIA
    Janine Krivokapich; Fiscal Year: 1990
    ..will have a baseline PET study with N-13 ammonia and either FDG or GLU prior to undergoing a supine exercise test. Repeat imaging with the same two isotopes will be performed sequentially with exercise testing, with the N-13 ..
  25. Sleep and Cytokines in Chronic Fatigue Syndrome
    Benjamin Natelson; Fiscal Year: 2007
    ..We will repeat this entire protocol after subjects perform a maximal exercise test and during a night of total sleep deprivation...
  26. EEFFECTS OF AEROBIC EXERCISE IN PERSONS WITH STROKE
    James Rimmer; Fiscal Year: 2003
    ..Prospective subjects will undergo a graded exercise test and blood test to screen out individuals with significant cardiac symptoms that would preclude exercise...
  27. OCCUPATIONAL WORK EVALUATION SOON AFTER CORONARY SURGERY
    Robert DeBusk; Fiscal Year: 1992
    ..The OWE has two parts: 1) a treadmill exercise test which demonstrates patients' capacity for occupational work followed by a counseling session with patient and ..
  28. DEVELOPMENT OF AN ALL-CAUSE MORTALITY RISK PROFILE
    Michael Smith; Fiscal Year: 1992
    ..mortality risk were developed, combining an objective measure of physical fitness, the maximal treadmill exercise test, with other risk factors identified in previous research (e.g...
  29. RANDOMIZED TRIAL OF REHABILITATION IN COPD
    Robert Kaplan; Fiscal Year: 1992
    ..Also perceived symptom ratings were taken with each exercise test. Data from the first year of follow-up have been evaluated and there are some significant differences between ..
  30. CORONARY ARTERY CALCIUM, EXERCISE TESTS, AND CHD OUTCOME
    MICHAEL LAMONTE; Fiscal Year: 2004
    Our goal is to evaluate coronary artery calcium (CAC) and exercise test results (cardiorespiratory fitness [CRF] and abnormal exercise tests) as predictors of coronary heart disease (CHD)...
  31. Functional MRI of diabetic peripheral vascular disease
    RONALD MEYER; Fiscal Year: 2003
    ..The MRI portion of this study will be accomplished during a single-session MRI-exercise test, which could be adapted for routine evaluation of peripheral vascular complications in diabetic patients...
  32. Functional MRI of diabetic peripheral vascular disease
    RONALD MEYER; Fiscal Year: 2002
    ..The MRI portion of this study will be accomplished during a single-session MRI-exercise test, which could be adapted for routine evaluation of peripheral vascular complications in diabetic patients...
  33. Prognostication In Idiopathic Interstitial Pneumonia
    Kevin Flaherty; Fiscal Year: 2006
    ..A drawback is the requirement of a cardiopulmonary exercise test. We hypothesize that a scoring system utilizing the change in oxygen saturation during a six-minute hall walk ..
  34. EXERCISE EFFECTS--MENTAL AND PHYSICAL HEALTH IN BREAST C
    Frank Perna; Fiscal Year: 2004
    ..Assessments will consist of a graded exercise test assessing cardiovascular fitness, body composition and strength analyses, and a psychosocial survey assessing ..
  35. INCREASING PHYSICAL ACTIVITY IN LOW INCOME WOMEN
    Abby King; Fiscal Year: 2000
    ..They will include reported PA levels and heart rate during a submaximal exercise test. Secondary outcomes include adherence to the exercise regimens, body mass index, blood pressure, waist-to-hip ..
  36. Continuous Measurement of Breathlessness
    John Baird; Fiscal Year: 2001
    ..Current methods for measuring breathlessness have patients provide ratings each minute during an incremental exercise test. Such "discrete" methods have limitations: 1) as patients breathe through a mouthpiece, they must point to a ..
  37. Metabolic Characterization of Six-minute Walk Testing
    Sanjay Patel; Fiscal Year: 2003
    ..Unlike maximal exercise testing (CPX), 6MWT is conventionally considered a sub-maximal exercise test and cannot delineate physiologic mechanisms for limitation...
  38. EPIDEMIOLOGY OF CORONARY CALCIFICATION IN THE ELDERLY
    Anne Newman; Fiscal Year: 2005
    ..cardiovascular events, we will evaluate the functional significance of the extent of calcification by an exercise test and will assess progression after 4 years by repeating the EBT scan, and determine the rate of new ..
  39. GENETIC EPIDEMIOLOGY OF CHD RISK FACTORS IN WOMEN TWINS
    Joe Selby; Fiscal Year: 1991
    ..A submaximal treadmill exercise test will be performed, if not medically contraindicated, to assess cardiovascular fitness and three questionnaires ..
  40. REPETITIVE EXERCISE AND CARDIAC ENLARGEMENT
    HUBERT STONE; Fiscal Year: 1980
    ..Physiological data will be obtained from the intact animal during an exercise test, cardiac pacing, and short coronary artery occlusions...
  41. Reducing Risk Factors in Peripheral Arterial Disease
    Mary Mcgrae McDermott; Fiscal Year: 2010
    ....
  42. Magnetic Resonance in Peripheral Arterial Disease
    Mary Mcgrae McDermott; Fiscal Year: 2010
    ..This knowledge, in subsequent studies, is expected to lead to new therapies for PAD-related functional impairment and functional decline. ..
  43. Home-based vs. Supervised Exercise for Claudicants
    Andrew W Gardner; Fiscal Year: 2010
    ....
  44. Inflammation and Peripheral Arterial Disease Outcomes
    Mary McDermott; Fiscal Year: 2008
    ..Results will be used to develop interventions to improve functioning and prevent functional decline in PAD. ..
  45. PERIPHERAL ARTERIAL DISEASE AND FUNCTIONAL OUTCOMES
    Mary McDermott; Fiscal Year: 2001
    ..They further state that the results of this study will be used to develop subsequent intervention studies designed to improve quality of life and prevent functional decline among men and women with PAD. ..
  46. Changes in Functional Status Across Therapy for Primary Glioma
    Lee Jones; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  47. Improving Functioning in Peripheral Arterial Disease
    Mary McDermott; Fiscal Year: 2007
    ..By identifying the optimal exercise program for improving functioning in PAD patients with and without IC, our findings will have substantial clinical and public health implications for millions of patients with PAD. ..
  48. Physical Activity and Quality of Life in Multiple Sclerosis
    Robert Motl; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  49. EXERCISE FOR ELDERLY PERIPHERAL REVASCULARIZED PATIENTS
    Andrew Gardner; Fiscal Year: 2004
    ....
  50. Mechanisms of Disability in Peripheral Arterial Disease
    Mary McDermott; Fiscal Year: 2005
    ..Results will be used to develop interventions designed to improve lower extremity functioning and prevent functional decline in persons with PAD. ..
  51. BLOOD FACTORS AND PERIPHERAL ARTERIAL DISEASE OUTCOMES
    Mary McDermott; Fiscal Year: 2004
    ....
  52. Effect of Daily Exercise on Cardiac Autonomic Regulation
    GEORGE BILLMAN; Fiscal Year: 2005
    ..Ventricular contractile responses to Beta1- and Beta2-adrenoceptor stimulation will be examined in vivo by echocardiography and in vitro by single cell fluorescence microscopy/video edge detection. ..
  53. Dietary Omega-3 Fatty Acids and Sudden Cardiac Death
    GEORGE EDWARD BILLMAN; Fiscal Year: 2010
    ..This project will also determine the effectiveness of fish oil supplements in reducing sudden death due to a lethal abnormal heart rhythm after a heart attack. ..
  54. Frequency of aerobic/resistance training in older women
    Gary Hunter; Fiscal Year: 2009
    ..Such information is critical to our understanding of ways to improve well being, quality of life, and independence of an aging population. ..
  55. RESPIRATION AND GLYCOLYSIS--INTEGRATION IN ACTIVE MUSCLE
    Kevin Conley; Fiscal Year: 2002
    ..g., diabetes. An understanding of the integration of metabolism in healthy tissue is the first step to understanding how failure of integration limits function in diseased muscle. ..
  56. ACTION - A CHF Trial Investigating Outcomes of Exercise
    Steven Keteyian; Fiscal Year: 2007
    ..The trial will take place over 5 years with an initial 6 months for planning, training, and implementation; 3 years of enrollment; 1 year of follow-up; and 6 months for close out, analysis, and presentation. ..
  57. BILATERAL COORDINATION OF HEMIPARETIC LOCOMOTION
    STEVEN KAUTZ; Fiscal Year: 2003
    ..g., muscular activity and afference related to loading and movement.) ..
  58. Effects of Vestibular Loss on Orthostatic Mechanisms
    Scott Wood; Fiscal Year: 2004
    ..This study will provide new information on how vestibular loss might increase susceptibility for orthostatic intolerance, and will provide new insights on otolith- autonomic human subjects. ..
  59. ACHILLES TENDON LENGTHENING ON PATIENTS WITH DIABETES
    Michael Mueller; Fiscal Year: 2002
    ....
  60. Cardiovascular Causes of Falls/Syncope in the Elderly
    Mathew Maurer; Fiscal Year: 2005
    ..abstract_text> ..
  61. GENETICS, EXERCISE AND BLOOD PRESSURE IN HYPERTENSIVES
    Leslie Katzel; Fiscal Year: 2003
    ..This research may lead to targeted lifestyle and pharmacologic therapies based on genotype to treat hypertension and CVD in older patients. ..
  62. WAGES: Workplace Activity for Employee Goal Setting
    RODNEY DISHMAN; Fiscal Year: 2006
    ..The project will implement and rigorously evaluate a multilevel physical activity intervention that has potential for broad application to workplace health promotion. ..
  63. Assessment and prediction of costs and adverse health outcomes in COPD
    Theodore Omachi; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable]..
  64. RESTENOSIS AND ENDOTHELIAL PROLIFERATION
    Douglas Losordo; Fiscal Year: 2007
    ..Together these studies will result in a better understanding of the mechanisms, which govern EC recovery at sites of balloon injury and may lead to novel therapeutic strategies targeting endothelial recovery. [unreadable] [unreadable]..
  65. Arterial Stiffness & Age-Effects on Circulatory Control
    J Taylor; Fiscal Year: 2007
    ..We seek renewed funding to examine fully sympatho-vagal interactions with age and disease and prospectively assess the effects of exercise. ..