confidence intervals

Summary

Summary: A range of values for a variable of interest, e.g., a rate, constructed so that this range has a specified probability of including the true value of the variable.

Top Publications

  1. pmc Genome sequence-based species delimitation with confidence intervals and improved distance functions
    Jan P Meier-Kolthoff
    Leibniz Institute DSMZ German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany
    BMC Bioinformatics 14:60. 2013
  2. pmc Overlapping confidence intervals or standard error intervals: what do they mean in terms of statistical significance?
    Mark E Payton
    Department of Statistics, Oklahoma State University, 301 MSCS Building, Stillwater, OK 74078 1056, USA
    J Insect Sci 3:34. 2003
  3. ncbi Assessing the probability that a positive report is false: an approach for molecular epidemiology studies
    Sholom Wacholder
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7244, USA
    J Natl Cancer Inst 96:434-42. 2004
  4. ncbi A multilevel model framework for meta-analysis of clinical trials with binary outcomes
    R M Turner
    MRC Clinical Trials Unit, 222 Euston Road, London NW1 2DA, UK
    Stat Med 19:3417-32. 2000
  5. ncbi Transitional care of older adults hospitalized with heart failure: a randomized, controlled trial
    Mary D Naylor
    Gerontological Nursing Science Center, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Am Geriatr Soc 52:675-84. 2004
  6. ncbi Quality of diagnosis and procedure coding in ICD-10 administrative data
    Toni Henderson
    Victorian Department of Human Services, Melbourne, Australia
    Med Care 44:1011-9. 2006
  7. pmc Risk of cancer in a large cohort of U.S. veterans with diabetes
    Elizabeth A Atchison
    Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, MD, USA
    Int J Cancer 128:635-43. 2011
  8. ncbi Calculating and graphing within-subject confidence intervals for ANOVA
    Thom Baguley
    Division of Psychology, School of Social Sciences, Nottingham Trent University, Nottingham NG1 4BU, UK
    Behav Res Methods 44:158-75. 2012
  9. pmc Standard errors and confidence intervals in within-subjects designs: generalizing Loftus and Masson (1994) and avoiding the biases of alternative accounts
    Volker H Franz
    Universitat Hamburg, Von Melle Park 5, 20146 Hamburg, Germany
    Psychon Bull Rev 19:395-404. 2012
  10. pmc Sensitivity of hospital-based surveillance for severe disease: a geographic information system analysis of access to care in Kilifi district, Kenya
    Jennifer C Moïsi
    KEMRI Wellcome Trust Research Programme, Kilifi, Kenya
    Bull World Health Organ 89:102-11. 2011

Detail Information

Publications366 found, 100 shown here

  1. pmc Genome sequence-based species delimitation with confidence intervals and improved distance functions
    Jan P Meier-Kolthoff
    Leibniz Institute DSMZ German Collection of Microorganisms and Cell Cultures, Braunschweig, Germany
    BMC Bioinformatics 14:60. 2013
    ..The main challenge in the implementation of such an application is to produce digital DDH values that must mimic the wet-lab DDH values as close as possible to ensure consistency in the Prokaryotic species concept...
  2. pmc Overlapping confidence intervals or standard error intervals: what do they mean in terms of statistical significance?
    Mark E Payton
    Department of Statistics, Oklahoma State University, 301 MSCS Building, Stillwater, OK 74078 1056, USA
    J Insect Sci 3:34. 2003
    We investigate the procedure of checking for overlap between confidence intervals or standard error intervals to draw conclusions regarding hypotheses about differences between population parameters...
  3. ncbi Assessing the probability that a positive report is false: an approach for molecular epidemiology studies
    Sholom Wacholder
    Biostatistics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892 7244, USA
    J Natl Cancer Inst 96:434-42. 2004
    ..An FPRP-based criterion for deciding whether to call a finding noteworthy formalizes the process already used informally by investigators--that is, tempering enthusiasm for remarkable study findings with considerations of plausibility...
  4. ncbi A multilevel model framework for meta-analysis of clinical trials with binary outcomes
    R M Turner
    MRC Clinical Trials Unit, 222 Euston Road, London NW1 2DA, UK
    Stat Med 19:3417-32. 2000
    ..Within summary data methods, confidence intervals for the overall treatment effect and for the between-trial variance may be derived from likelihood based ..
  5. ncbi Transitional care of older adults hospitalized with heart failure: a randomized, controlled trial
    Mary D Naylor
    Gerontological Nursing Science Center, School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Am Geriatr Soc 52:675-84. 2004
    ..To examine the effectiveness of a transitional care intervention delivered by advanced practice nurses (APNs) to elders hospitalized with heart failure...
  6. ncbi Quality of diagnosis and procedure coding in ICD-10 administrative data
    Toni Henderson
    Victorian Department of Human Services, Melbourne, Australia
    Med Care 44:1011-9. 2006
    ....
  7. pmc Risk of cancer in a large cohort of U.S. veterans with diabetes
    Elizabeth A Atchison
    Division of Cancer Epidemiology and Genetics, NCI, NIH, DHHS, Bethesda, MD, USA
    Int J Cancer 128:635-43. 2011
    ..Poisson regression was used to estimate adjusted relative risks (RRs) and 95% confidence intervals (CIs). Overall, men with diabetes had a significantly lower risk of cancer (RR = 0.93, 95%CI = 0.93-0.94)...
  8. ncbi Calculating and graphing within-subject confidence intervals for ANOVA
    Thom Baguley
    Division of Psychology, School of Social Sciences, Nottingham Trent University, Nottingham NG1 4BU, UK
    Behav Res Methods 44:158-75. 2012
    The psychological and statistical literature contains several proposals for calculating and plotting confidence intervals (CIs) for within-subjects (repeated measures) ANOVA designs...
  9. pmc Standard errors and confidence intervals in within-subjects designs: generalizing Loftus and Masson (1994) and avoiding the biases of alternative accounts
    Volker H Franz
    Universitat Hamburg, Von Melle Park 5, 20146 Hamburg, Germany
    Psychon Bull Rev 19:395-404. 2012
    ..Because of the correlational structure in these designs, the calculation and interpretation of confidence intervals is nontrivial...
  10. pmc Sensitivity of hospital-based surveillance for severe disease: a geographic information system analysis of access to care in Kilifi district, Kenya
    Jennifer C Moïsi
    KEMRI Wellcome Trust Research Programme, Kilifi, Kenya
    Bull World Health Organ 89:102-11. 2011
    ..To explore the relationship between homestead distance to hospital and access to care and to estimate the sensitivity of hospital-based surveillance in Kilifi district, Kenya...
  11. ncbi Inference by eye: confidence intervals and how to read pictures of data
    Geoff Cumming
    School of Psychological Science, La Trobe University, Melbourne, Victoria, Australia
    Am Psychol 60:170-80. 2005
    Wider use in psychology of confidence intervals (CIs), especially as error bars in figures, is a desirable development. However, psychologists seldom use CIs and may not understand them well...
  12. pmc Methods for estimating confidence intervals in interrupted time series analyses of health interventions
    Fang Zhang
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    J Clin Epidemiol 62:143-8. 2009
    ..We describe and illustrate two methods for estimating confidence intervals (CIs) around absolute and relative changes in outcomes calculated from segmented regression parameter ..
  13. pmc Poor performance of bootstrap confidence intervals for the location of a quantitative trait locus
    Ani Manichaikul
    Department of Biostatistics, Johns Hopkins University, Baltimore, Maryland 21205 2179, USA
    Genetics 174:481-9. 2006
    ..b>Confidence intervals for the locations of QTL are particularly important for the design of further experiments to identify the ..
  14. ncbi Determination of confidence intervals of metabolic fluxes estimated from stable isotope measurements
    Maciek R Antoniewicz
    Department of Chemical Engineering, Bioinformatics and Metabolic Engineering Laboratory, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge MA 02139, USA
    Metab Eng 8:324-37. 2006
    ..Furthermore, we developed an efficient algorithm to determine accurate flux confidence intervals and demonstrated that confidence intervals obtained with this method closely approximate true flux ..
  15. pmc Primary care, economic barriers to health care, and use of colorectal cancer screening tests among Medicare enrollees over time
    Chyke A Doubeni
    Department of Family Medicine and Community Health, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
    Ann Fam Med 8:299-307. 2010
    ..The objective of this study was to examine the impact of primary care and economic barriers to health care on CRC testing relative to the 2001 Medicare expansion of screening coverage...
  16. ncbi A comparison of confidence interval methods for the intraclass correlation coefficient in cluster randomized trials
    Obioha C Ukoumunne
    Department of Public Health Sciences, King s College London, 5th Floor, Capital House, 42 Weston Street, London SE1 3QD, UK
    Stat Med 21:3757-74. 2002
    This study compared different methods for assigning confidence intervals to the analysis of variance estimator of the intraclass correlation coefficient (rho)...
  17. ncbi Relative risks and confidence intervals were easily computed indirectly from multivariable logistic regression
    A Russell Localio
    Division of Biostatistics, Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104 6021, USA
    J Clin Epidemiol 60:874-82. 2007
    To assess alternative statistical methods for estimating relative risks and their confidence intervals from multivariable binary regression when outcomes are common.
  18. ncbi Confidence intervals for the overall effect size in random-effects meta-analysis
    Julio Sánchez-Meca
    Department of Basic Psychology and Methodology, Faculty of Psychology, Espinardo Campus, University of Murcia, Murcia, Spain
    Psychol Methods 13:31-48. 2008
    ..The results of a Monte Carlo simulation showed that the weighted variance CI outperformed the other methods regardless of the tau2 estimator, the value of tau2, the number of studies, and the sample size...
  19. ncbi Association between workaholism and sleep problems among hospital nurses
    Kazumi Kubota
    Department of Mental Health, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan
    Ind Health 48:864-71. 2010
    ..However, no significant associations were found between workaholism and insomnia symptoms. These results suggest that workaholic nurses had higher risks for impaired awakening, insufficient sleep, and workplace sleepiness...
  20. ncbi Do emergency physicians attribute drug-related emergency department visits to medication-related problems?
    Corinne M Hohl
    Department of Emergency Medicine, University of British Columbia, Vancouver General Hospital, 855 West 12th Avenue, Vancouver, BC, Canada
    Ann Emerg Med 55:493-502.e4. 2010
    ..Our objective is to determine the proportion of drug-related visits emergency physicians attribute to medication-related problems...
  21. ncbi Confidence intervals for the amount of heterogeneity in meta-analysis
    Wolfgang Viechtbauer
    Department of Methodology and Statistics, University of Maastricht, P O Box 616, 6200 MD Maastricht, The Netherlands
    Stat Med 26:37-52. 2007
    ..A novel method for constructing confidence intervals for the amount of heterogeneity in the effect sizes is proposed that guarantees nominal coverage ..
  22. ncbi The annual incidence and course of neck pain in the general population: a population-based cohort study
    Pierre Cote
    Institute for Work and Health, 481 University Avenue, Toronto, Ont, Canada M5G 2E9
    Pain 112:267-73. 2004
    ..63-0.88). Neck pain is a disabling condition with a course marked by periods of remission and exacerbation. Contrary to prior belief, most individuals with neck pain do not experience complete resolution of their symptoms and disability...
  23. pmc Confidence intervals that match Fisher's exact or Blaker's exact tests
    Michael P Fay
    Biostatistics Research Branch, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892 7609, USA
    Biostatistics 11:373-4. 2010
    ..Fisher's exact test may not be an interval, so following Blaker (2000, Confidence curves and improved exact confidence intervals for discrete distributions...
  24. ncbi Characteristics, outcomes, and predictors of mortality at 3 months and 1 year in patients hospitalized for acute heart failure
    Veli Pekka Harjola
    Division of Emergency Care, Department of Medicine, Helsinki University Central Hospital, PO Box 340, Helsinki 00029 HUS, Finland
    Eur J Heart Fail 12:239-48. 2010
    ..Acute heart failure (AHF) has a poor prognosis. We evaluated 3- and 12-month mortality in different clinical classes of AHF patients from 30 European countries who were included in the EuroHeart Failure Survey (EHFS) II...
  25. ncbi Intimate partner violence: prevalence and risk factors for men in Cape Town, South Africa
    Naeemah Abrahams
    Gender and Health Unit, Medical Research Council, Tygerberg, South Africa
    Violence Vict 21:247-64. 2006
    ..16), and conflict about his infidelity (OR = 2.81). The study shows that ideas supportive of gender inequality and normative use of violence in different settings are major underlying factors for men's violence against partners...
  26. ncbi Sample size requirements for estimating intraclass correlations with desired precision
    Douglas G Bonett
    Department of Statistics, Iowa State University, Snedecor Hall, Ames, IA 50011 1210, USA
    Stat Med 21:1331-5. 2002
    ..The sample size approximation is shown to be very accurate...
  27. pmc NQO1 polymorphisms and de novo childhood leukemia: a HuGE review and meta-analysis
    Neela Guha
    Division of Epidemiology, School of Public Health, University of California, Berkeley, California 94704, USA
    Am J Epidemiol 168:1221-32. 2008
    ..Therefore, further research is warranted on the role of NQO1 polymorphisms in the etiology of childhood leukemia, especially among MLL-positive leukemias...
  28. ncbi Cigarette advertising and adolescent smoking
    Reiner Hanewinkel
    Institute for Therapy and Health Research, Kiel, Germany
    Am J Prev Med 38:359-66. 2010
    ..Although most agree that the association between tobacco marketing and youth smoking is causal, few studies have assessed the specificity of this association...
  29. ncbi Epidemic of coeliac disease in Swedish children
    A Ivarsson
    Department of Clinical Science, Umea University, Sweden
    Acta Paediatr 89:165-71. 2000
    ..e. amount of gluten given, age at introduction of gluten, and whether breastfeeding was ongoing or not when gluten was introduced. Other factor(s) may also have contributed, and the search for these should be intensified...
  30. ncbi Occupational asthma in Europe and other industrialised areas: a population-based study. European Community Respiratory Health Survey Study Group
    M Kogevinas
    Respiratory and Environmental Health Research Unit, Institut Municipal d Investigacio Medica, Barcelona, Spain
    Lancet 353:1750-4. 1999
    ..There are no large population-based studies on occupational asthma, and few estimates of the proportion of asthma attributed to occupation, even though asthma is the most common occupational respiratory disorder in industrialised countries...
  31. ncbi Frequentist performance of Bayesian confidence intervals for comparing proportions in 2 x 2 contingency tables
    Alan Agresti
    Department of Statistics, University of Florida, Gainesville, Florida 32611, USA
    Biometrics 61:515-23. 2005
    This article investigates the performance, in a frequentist sense, of Bayesian confidence intervals (CIs) for the difference of proportions, relative risk, and odds ratio in 2 x 2 contingency tables...
  32. pmc Incidence and remaining lifetime risk of Parkinson disease in advanced age
    Jane A Driver
    Division of Aging, Department of Medicine, Brigham and Women s Hospital, Harvard Medical School, Boston, MA 02120, USA
    Neurology 72:432-8. 2009
    ..To estimate the incidence and lifetime risk (LTR) of Parkinson disease (PD) in a large cohort of men...
  33. ncbi Childhood social and economic well-being and health in older age
    Sandra Moody-Ayers
    San Francisco VA Medical Center, San Francisco, CA 94121, USA
    Am J Epidemiol 166:1059-67. 2007
    ..14, 1.64) participants but not Latinos. These findings suggest that childhood SES affects health status through midlife but the effects may abate in late life; its effects also may be weaker in Latinos than in Whites or Blacks...
  34. ncbi Sexual and drug-related vulnerabilities for HIV infection among women engaged in survival sex work in Vancouver, Canada
    Kate Shannon
    British Columbia Centre for Excellence in HIV AIDS, St Paul s Hospital, Vancouver, BC, Canada
    Can J Public Health 98:465-9. 2007
    ..This analysis aimed to determine HIV prevalence among women engaged in survival sex work, and explore sexual and drug-related vulnerabilities associated with baseline infection...
  35. ncbi Nonalcoholic fatty liver disease in patients with hepatitis C is associated with features of the metabolic syndrome
    Arun J Sanyal
    Department of Pathology, Virginia Commonwealth University Health System, Richmond, Virginia, USA
    Am J Gastroenterol 98:2064-71. 2003
    ....
  36. ncbi Maternal and neonatal outcomes of assaults during pregnancy
    Dina El Kady
    Department of Obstetrics and Gynecology, University of California Davis, 4860 Y Street, Sacramento, CA 95817, USA
    Obstet Gynecol 105:357-63. 2005
    ..To assess perinatal outcomes of women hospitalized for assault during pregnancy as a function of timing of delivery...
  37. pmc Colorectal cancer screening by primary care physicians: recommendations and practices, 2006-2007
    Carrie N Klabunde
    Health Services and Economics Branch, Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, Bethesda, Maryland 20892 7344, USA
    Am J Prev Med 37:8-16. 2009
    ..S. This study describes the CRC screening recommendations and practices of U.S. physicians and compares them to findings from a 1999-2000 national provider survey...
  38. pmc Vitamin D-deficiency rickets among children in Canada
    Leanne M Ward
    Department of Pediatrics, Children s Hospital of Eastern Ontario, University of Ottawa, Ottawa, Ont
    CMAJ 177:161-6. 2007
    ..We sought to determine the incidence and clinical characteristics of vitamin D-deficiency rickets among children living in Canada...
  39. ncbi A comparison of approaches to estimating confidence intervals for willingness to pay measures
    Arne Risa Hole
    National Primary Care Research and Development Centre, Centre for Health Economics, University of York, UK
    Health Econ 16:827-40. 2007
    This paper describes four approaches to estimating confidence intervals for willingness to pay measures: the delta, Fieller, Krinsky Robb and bootstrap methods...
  40. ncbi Tobacco smoking behaviors in bipolar disorder: a comparison of the general population, schizophrenia, and major depression
    Francisco J Diaz
    Department of Statistics, Universidad Nacional, Medellin, Colombia
    Bipolar Disord 11:154-65. 2009
    ..The main goal was to establish that bipolar patients smoke more than normal controls. Differences with psychiatric controls were explored...
  41. ncbi Polymorphisms in multidrug resistance 1 (MDR1) gene are associated with refractory Crohn disease and ulcerative colitis
    U Potocnik
    Laboratory of Molecular Genetics, Institute of Pathology, Medical Faculty, Ljubljana, Slovenia
    Genes Immun 5:530-9. 2004
    ..7 and P=0.025, OR 2.8, respectively), as well as with UC (P=0.006, OR 1.8 and P=0.026, OR 1.9, respectively). Our results suggest that MDR1 is a potential target for therapy in refractory CD patients and in patients with UC...
  42. pmc Determining confidence intervals when measuring genetic diversity and the discriminatory abilities of typing methods for microorganisms
    H Grundmann
    Division of Microbiology and Infectious Diseases, University Hospital Nottingham, University of Nottingham, Nottingham NG7 2UH, United Kingdom
    J Clin Microbiol 39:4190-2. 2001
    We describe here a method for determining confidence intervals for a commonly used index of diversity...
  43. pmc Meta- and pooled analyses of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and colorectal cancer: a HuGE-GSEC review
    E Taioli
    SUNY Downstate Medical Center, Brooklyn, New York 11203, USA
    Am J Epidemiol 170:1207-21. 2009
    ..The MTHFR 677TT polymorphism seems to be associated with a reduced risk of CRC, but this may not hold true for all populations...
  44. ncbi Prospective studies of dairy product and calcium intakes and prostate cancer risk: a meta-analysis
    Xiang Gao
    Jean Mayer USDA Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA
    J Natl Cancer Inst 97:1768-77. 2005
    ..We conducted a meta-analysis to examine associations between intakes of calcium and dairy products and the risk of prostate cancer...
  45. ncbi Childhood circumstances and anthropometry: the Boyd Orr cohort
    Elise Whitley
    Department of Social Medicine, Bristol BS8 2PR, UK
    Ann Hum Biol 35:518-34. 2008
    ....
  46. pmc How accurate are self-reports? Analysis of self-reported health care utilization and absence when compared with administrative data
    Meghan E Short
    Division of Health and Productivity Research, Thomson Reuters Healthcare, Washington, DC, USA
    J Occup Environ Med 51:786-96. 2009
    ..To determine the accuracy of self-reported health care utilization and absence reported on health risk assessments against administrative claims and human resource records...
  47. ncbi Shallow medial tibial plateau and steep medial and lateral tibial slopes: new risk factors for anterior cruciate ligament injuries
    Javad Hashemi
    Department of Mechanical Engineering, Texas Tech University, 7th and Boston Streets, Lubbock, TX 79409 1021, USA
    Am J Sports Med 38:54-62. 2010
    ....
  48. ncbi Attitudes and managing alcohol problems in general practice: an interaction analysis based on findings from a WHO collaborative study
    Peter Anderson
    Centre for Quality of Care Research, University Medical Centre Nijmegen, 229 WOK, PO Box 9101, 6500 HB, The Netherlands
    Alcohol Alcohol 39:351-6. 2004
    ..To determine if GPs' attitudes towards working with drinkers moderated the impact that training and support had on screening and brief intervention activity in routine practice...
  49. ncbi Consumption of filtered and boiled coffee and the risk of incident cancer: a prospective cohort study
    Lena Maria Nilsson
    Department of Public Health and Clinical Medicine, Nutritional Research, Umea University, Umea, Sweden
    Cancer Causes Control 21:1533-44. 2010
    ..Despite potentially relevant chemical differences between filtered and boiled coffee, this study is the first to investigate consumption in relation to the risk of incident cancer...
  50. ncbi Prevalence of active epilepsy in a rural area in South Tanzania: a door-to-door survey
    Wolfgang Dent
    Department of Neurology, Medical University Innsbruck, Innsbruck, Austria
    Epilepsia 46:1963-9. 2005
    ..A door-to-door survey was carried out to assess the prevalence of active epilepsy in the rural population within the catchment area of the Mnero Diocesan Hospital in Southern Tanzania...
  51. ncbi The psychometric function: II. Bootstrap-based confidence intervals and sampling
    F A Wichmann
    University of Oxford, England
    Percept Psychophys 63:1314-29. 2001
    ..scheme (the placement of sample points on the stimulus axis) strongly affects the reliability of bootstrap confidence intervals, and we make recommendations on how to sample the psychometric function efficiently...
  52. ncbi Association between tobacco consumption and alcohol, vegetable and fruit intake across urban and rural areas in Mozambique
    Patrícia Padrão
    Serviço de Higiene e Epidemiologia, Faculdade de Medicina da Universidade do Porto, Al Prof Hernani Monteiro, Porto, Portugal
    J Epidemiol Community Health 65:445-53. 2011
    ....
  53. pmc Trends in rates of different forms of diagnosed coronary heart disease, 1978 to 2000: prospective, population based study of British men
    Fiona C Lampe
    Department of Primary Care and Population Sciences, Royal Free and University College Medical School, London NW3 2PF
    BMJ 330:1046. 2005
    ..To examine trends over time in rates of different forms of diagnosed coronary heart disease among British men, during a period in which mortality due to coronary heart disease has been declining...
  54. ncbi Meta-analysis on the association between environmental tobacco smoke (ETS) exposure and the prevalence of lower respiratory tract infection in early childhood
    J S Li
    Department of Medicine, University of Sydney, Australia
    Pediatr Pulmonol 27:5-13. 1999
    ..New public health campaigns are urgently needed to discourage smoking in the presence of young children...
  55. ncbi Adjustments for center in multicenter studies: an overview
    A R Localio
    Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, 606 Blockley Hall, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
    Ann Intern Med 135:112-23. 2001
    ..resulting from the similarity of outcomes among patients within a center, requires an adjustment to confidence intervals and P values, especially in observational studies and in randomized multicenter studies in which treatment ..
  56. ncbi Anemia and mortality in heart failure patients a systematic review and meta-analysis
    Hessel F Groenveld
    Department of Cardiology, University Medical Center Groningen, Groningen, The Netherlands
    J Am Coll Cardiol 52:818-27. 2008
    ..The aim of this study was to assess the effect of anemia on mortality in chronic heart failure (CHF)...
  57. pmc Dairy food, calcium, and risk of cancer in the NIH-AARP Diet and Health Study
    Yikyung Park
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, 6120 Executive Blvd, Bethesda, MD 20852, USA
    Arch Intern Med 169:391-401. 2009
    ..Dairy food and calcium intakes have been hypothesized to play roles that differ among individual cancer sites, but the evidence has been limited and inconsistent. Moreover, their effect on cancer in total is unclear...
  58. ncbi Bayesian meta-analysis of multiple treatment comparisons: an introduction to mixed treatment comparisons
    Jeroen P Jansen
    Mapi Values Ltd, Boston, MA 02108, USA
    Value Health 11:956-64. 2008
    ..Next, the Bayesian MTC for continuous outcomes are presented. We finish with a discussion of how MTC can best be presented in order to maximize acceptance by target audiences, i.e., clinicians and market access decision-makers...
  59. pmc Incongruence between test statistics and P values in medical papers
    Emili García-Berthou
    Department of Environmental Sciences, University of Girona, E 17071 Girona, Spain
    BMC Med Res Methodol 4:13. 2004
    ..Given an observed test statistic and its degrees of freedom, one may compute the observed P value with most statistical packages. It is unknown to what extent test statistics and P values are congruent in published medical papers...
  60. pmc High dynamic range characterization of the trauma patient plasma proteome
    Tao Liu
    Biological Sciences Division and Environmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory, Richland, Washington 99354, USA
    Mol Cell Proteomics 5:1899-913. 2006
    ....
  61. ncbi Monte Carlo simulation of parameter confidence intervals for non-linear regression analysis of biological data using Microsoft Excel
    Ronald J W Lambert
    Applied Microbiology Group, Cranfield Health, Cranfield University, Cranfield, UK
    Comput Methods Programs Biomed 107:155-63. 2012
    This study describes a method to obtain parameter confidence intervals from the fitting of non-linear functions to experimental data, using the SOLVER and Analysis ToolPaK Add-In of the Microsoft Excel spreadsheet...
  62. ncbi Sex differences in risk factors for hiv seroconversion among injection drug users: a 10-year perspective
    S A Strathdee
    Department of Epidemiology, Johns Hopkins School of Public Health, 615 N Wolfe St, Room E6010, Baltimore, MD 21205, USA
    Arch Intern Med 161:1281-8. 2001
    ..Prospective studies that investigate both sexual and parenteral HIV risks among injection drug users (IDUs) are needed. We studied factors for HIV seroconversion among male and female IDUs in Baltimore, Md...
  63. ncbi Social disparities, communication inequalities, and HIV/AIDS-related knowledge and attitudes in India
    Leland K Ackerson
    Department of Community Health and Sustainability, University of Massachusetts Lowell, 3 Solomont Way, Lowell, MA 01854, USA
    AIDS Behav 16:2072-81. 2012
    ..men in the 2005-2006 National Family Health Survey were used to calculate relative risk estimates and 95% confidence intervals for these associations...
  64. pmc Extensions to decision curve analysis, a novel method for evaluating diagnostic tests, prediction models and molecular markers
    Andrew J Vickers
    Department of Epidemiology and Biostatistics, Memorial Sloan Kettering Cancer Center, 307 East 63rd Street, New York, NY 10065, USA
    BMC Med Inform Decis Mak 8:53. 2008
    ..Most critically, decision curve analysis can be applied directly to a data set, and does not require the sort of external data on costs, benefits and preferences typically required by traditional decision analytic techniques...
  65. pmc Statistics review 8: Qualitative data - tests of association
    Viv Bewick
    Senior Lecturer, School of Computing, Mathematical and Information Sciences, University of Brighton, Brighton, UK
    Crit Care 8:46-53. 2004
    ..Risk measurement is discussed. The calculation of confidence intervals for proportions and differences between proportions are described...
  66. ncbi Validity of two self-report measures of sitting time
    Stacy A Clemes
    School of Sport, Exercise, and Health Sciences, Loughborough University, Loughborough, United Kingdom
    J Phys Act Health 9:533-9. 2012
    ..This study examined the convergent validity of 2 self-report measures of sitting time and accelerometer-determined sedentary time (minutes/day of <100 counts/minute)...
  67. pmc RMediation: an R package for mediation analysis confidence intervals
    Davood Tofighi
    School of Psychology, Georgia Institute of Technology, J S Coon Bldg 654 Cherry Street, Atlanta, GA 30332 0170, USA
    Behav Res Methods 43:692-700. 2011
    This article describes the RMediation package,which offers various methods for building confidence intervals (CIs) for mediated effects. The mediated effect is the product of two regression coefficients...
  68. ncbi Toward using confidence intervals to compare correlations
    Guang Yong Zou
    Department of Epidemiology and Biostatistics, Schulich School of Medicine and Dentistry, University of Western Ontario, London, Ontario, Canada
    Psychol Methods 12:399-413. 2007
    b>Confidence intervals are widely accepted as a preferred way to present study results. They encompass significance tests and provide an estimate of the magnitude of the effect...
  69. ncbi Representing uncertainty: the role of cost-effectiveness acceptability curves
    E Fenwick
    Centre for Health Economics, University of York, York, UK
    Health Econ 10:779-87. 2001
    ..We hope that as a result we can encourage the greater use of these techniques...
  70. pmc Induced abortion, pregnancy loss and intimate partner violence in Tanzania: a population based study
    Heidi Stöckl
    Department of Global Health and Development, London School of Hygiene and Tropical Medicine, Keppel Street, London, UK
    BMC Pregnancy Childbirth 12:12. 2012
    ....
  71. ncbi Relation of leisure time, occupational, domestic, and commuting physical activity to health indicators in Europe
    Karim Abu-Omar
    Institute of Sport Science and Sport, Friedrich Alexander University Erlangen Nuremberg, Germany
    Prev Med 47:319-23. 2008
    ..To investigate relationships between physical activities in different domains (leisure time, occupational, domestic, commuting) and health indicators (self-rated health, body mass index)...
  72. ncbi Challenge to long term care for the elderly: cold weather impacts institutional population more than community-dwelling population
    Pui Hing Chau
    University of Hong Kong, Pokfulam, Hong Kong, China
    J Am Med Dir Assoc 13:788-93. 2012
    ..To examine whether cold weather affects the institutional population more than the community-dwelling population in terms of morbidity requiring hospital admission...
  73. ncbi A randomised controlled trial of the Home Independence Program, an Australian restorative home-care programme for older adults
    Gill Lewin
    Centre for Research on Ageing, Curtin Health Innovation Research Institute, Curtin University, Perth, Australia
    Health Soc Care Community 21:69-78. 2013
    ....
  74. pmc Methods and software for estimating health disparities: the case of children's oral health
    Nancy F Cheng
    Division of Oral Epidemiology and Dental Public Health, University of California, San Francisco, 3333 California Street, Suite 495, San Francisco, CA 94143 1361, USA
    Am J Epidemiol 168:906-14. 2008
    ..However, guidelines on confidence intervals (CIs) cannot be readily implemented with the complex sample surveys often used for disease surveillance...
  75. ncbi Long-term analgesic use after low-risk surgery: a retrospective cohort study
    Asim Alam
    Department of Anesthesiology, University of Toronto, Ontario, Canada
    Arch Intern Med 172:425-30. 2012
    ..This study evaluated the risk of long-term analgesic use after low-risk surgery in older adults not previously prescribed analgesics...
  76. ncbi The exact distribution of Cochran's heterogeneity statistic in one-way random effects meta-analysis
    Brad J Biggerstaff
    Division of Vector Borne Infectious Diseases, National Center for Zoonotic, Vector Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Fort Collins, CO 80521, USA
    Stat Med 27:6093-110. 2008
    ..measures I(2) and H(M)(2), the power of the standard test for the presence of heterogeneity and confidence intervals for the between-study variance parameter when the DerSimonian-Laird or the Hartung-Makambi estimator is ..
  77. ncbi Confidence intervals for effect sizes: compliance and clinical significance in the Journal of Consulting and clinical Psychology
    Eric C Odgaard
    Department of Psychology, University of South Florida, St Petersburg, FL 33701, USA
    J Consult Clin Psychol 78:287-97. 2010
    ..journal to require statistical measures of clinical significance, plus effect sizes (ESs) and associated confidence intervals (CIs), for primary outcomes (La Greca, 2005)...
  78. ncbi Habitual active transport moderates the association of TV viewing time with body mass index
    Takemi Sugiyama
    Cancer Prevention Research Centre, The University of Queensland, Brisbane, Australia
    J Phys Act Health 7:11-6. 2010
    ..However, it is unknown whether the relationship of TV viewing time with body mass index (BMI) is moderated by other domains of physical activity...
  79. pmc Case-finding instruments for depression. Two questions are as good as many
    M A Whooley
    General Internal Medicine Section, San Francisco Department of Veterans Affairs Medical Center, CA 94121, USA
    J Gen Intern Med 12:439-45. 1997
    ..82 to 0.89. CONCLUSIONS: The two-question case-finding instrument is a useful measure for detecting depression in primary care. It has similar test characteristics to other case-finding instruments and is less time-consuming...
  80. ncbi Properties of Weir and Cockerham's Fst estimators and associated bootstrap confidence intervals
    Sivan Leviyang
    Georgetown University, Department of Mathematics, United States
    Theor Popul Biol 79:39-52. 2011
    ..We use these results to analyze confidence interval construction for θ, showing that the percentile-t bootstrap works well while the BCa bootstrap works poorly. Our results are derived using a novel coalescent based method...
  81. ncbi Depressive disorder and incident diabetes mellitus: the effect of characteristics of depression
    Antonio Campayo
    Instituto Aragones de Ciencias de la Salud I CS, Zaragoza, Spain
    Am J Psychiatry 167:580-8. 2010
    ..The authors examined the effect of characteristics of depression frequently found in the community on the risk of incident diabetes mellitus...
  82. pmc Oxidative DNA damage in early pregnancy and risk of gestational diabetes mellitus: A pilot study
    Chunfang Qiu
    Center for Perinatal Studies, Swedish Medical Center, Seattle, Washington, USA
    Clin Biochem 44:804-8. 2011
    ..To examine the association of maternal early pregnancy oxidative stress with risk of gestational diabetes mellitus (GDM)...
  83. ncbi Validity and reliability of the Malay-language translation of the Rome III Diagnostic Questionnaire for irritable bowel syndrome
    Yeong Yeh Lee
    Department of Medicine, Universiti Sains Malaysia, Kubang Kerian, Kelantan, Malaysia
    J Gastroenterol Hepatol 27:746-50. 2012
    ..The current study aimed to translate and validate the Rome III IBS Diagnostic Questionnaire, Red Flag and Psychosocial Alarm questionnaires into the Malay language...
  84. pmc SAPS 3--From evaluation of the patient to evaluation of the intensive care unit. Part 2: Development of a prognostic model for hospital mortality at ICU admission
    Rui P Moreno
    Unidade de Cuidados Intensivos Polivalente, Hospital de St António dos Capuchos, Centro Hospitalar de Lisboa zona central, Lisbon, Portugal
    Intensive Care Med 31:1345-55. 2005
    ..To develop a model to assess severity of illness and predict vital status at hospital discharge based on ICU admission data...
  85. pmc Calibrating predictive model estimates to support personalized medicine
    Xiaoqian Jiang
    Division of Biomedical Informatics, School of Medicine, University of California, San Diego, La Jolla, California 92093, USA
    J Am Med Inform Assoc 19:263-74. 2012
    ..Our goal is to develop a new calibration method to conserve as much information as possible, and would compare favorably to existing methods in terms of important performance measures: discrimination and calibration...
  86. ncbi Constructing confidence intervals for cost-effectiveness ratios: an evaluation of parametric and non-parametric techniques using Monte Carlo simulation
    A H Briggs
    Health Economics Research Centre, Oxford Institute of Health Sciences and Nuffield College, University of Oxford, U K
    Stat Med 18:3245-62. 1999
    ..intractable, the health economics literature has suggested a number of alternative approaches to estimating confidence intervals for the cost-effectiveness ratio...
  87. pmc Why do children from socioeconomically disadvantaged families suffer from poor health when they reach adulthood? A life-course study
    Maria Melchior
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, United Kingdom
    Am J Epidemiol 166:966-74. 2007
    ..No single risk factor emerged as the prime explanation, suggesting that the processes mediating the link between childhood low SES and adult poor health are multifactorial...
  88. ncbi Genital human papillomavirus infection: incidence and risk factors in a cohort of female university students
    Rachel L Winer
    Department of Epidemiology, University of Washington, Seattle, WA 98103, USA
    Am J Epidemiol 157:218-26. 2003
    ..The data show that the incidence of HPV associated with acquisition of a new sex partner is high and that nonpenetrative sexual contact is a plausible route of transmission in virgins...
  89. pmc Risk of estrogen receptor-positive and -negative breast cancer and single-nucleotide polymorphism 2q35-rs13387042
    Roger L Milne
    Genetic and Molecular Epidemiology Group, Human Cancer Genetics Program, Spanish National Cancer Research Centre CNIO, 29029 Madrid, Spain
    J Natl Cancer Inst 101:1012-8. 2009
    ..We attempted to confirm this association using the Breast Cancer Association Consortium...
  90. ncbi Race and food store availability in an inner-city neighbourhood
    Maida P Galvez
    Department of Community and Preventive Medicine, Mount Sinai School of Medicine, New York, NY 10029, USA
    Public Health Nutr 11:624-31. 2008
    ..Less is known about whether differences in availability of resources by African American or Latino race/ethnicity exist within a single minority community...
  91. ncbi A palliative-care intervention and death at home: a cluster randomised trial
    M S Jordhøy
    Unit of Applied Clinical Research, Norwegian University of Science and Technology, Kreftbygget, University Hospital of Trondheim
    Lancet 356:888-93. 2000
    ..We did a cluster randomised trial to assess the intervention's effectiveness compared with conventional care..
  92. ncbi Hierarchical models in ecology: confidence intervals, hypothesis testing, and model selection using data cloning
    José Miguel Ponciano
    Centro de Investigacíon en Matemáticas, CIMAT A C Calle Jalisco s n, Col Valenciana, A P 402, C P 36240 Guanajuato, Guanajuato, Mexico
    Ecology 90:356-62. 2009
    ..Despite its generality, the method has two inferential limitations. First, it only provides Wald-type confidence intervals, known to be inaccurate in small samples...
  93. ncbi Dealing with discreteness: making 'exact' confidence intervals for proportions, differences of proportions, and odds ratios more exact
    A Agresti
    Department of Statistics, University of Florida, Gainesville, Florida 32611 8545, USA
    Stat Methods Med Res 12:3-21. 2003
    ..However, they are conservative inferentially. The actual error probabilities for tests and confidence intervals are bounded above by the nominal level...
  94. ncbi Odds ratio, relative risk, absolute risk reduction, and the number needed to treat--which of these should we use?
    Edna Schechtman
    Department of Industrial Engineering and Management, Ben Gurion University of the Negev, Beer Sheva, Israel
    Value Health 5:431-6. 2002
    ..The question faced by the practitioner is then: Which one will help me in choosing the best treatment for my patient?..
  95. pmc Internet-based treatment for adults with depressive symptoms: randomized controlled trial
    Lisanne Warmerdam
    Dept Clinical Psychology, VU University Amsterdam, FPP, Amsterdam, The Netherlands
    J Med Internet Res 10:e44. 2008
    ..Depression can be treated effectively with Internet-based cognitive behavioral therapy (CBT), but a short intervention based on problem solving therapy (PST) could constitute a worthwhile alternative to CBT...
  96. ncbi Multiple inferences using confidence intervals
    J Ludbrook
    Carlton North, Victoria, Australia
    Clin Exp Pharmacol Physiol 27:212-5. 2000
    ..3. However, some investigators prefer to estimate effect sizes and make inferences by way of confidence intervals rather than, or in addition to, testing hypotheses by way of P values and it is the policy of some editors ..
  97. ncbi Second-trimester abortion for fetal anomalies or fetal death: labor induction compared with dilation and evacuation
    Amy G Bryant
    Department of Obstetrics and Gynecology, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA
    Obstet Gynecol 117:788-92. 2011
    ..To compare the safety and effectiveness of dilation and evacuation (D&E) and labor-induction abortion performed for fetal anomalies or fetal death in the second trimester...
  98. ncbi The ongoing tyranny of statistical significance testing in biomedical research
    Andreas Stang
    Institut für Klinische Epidemiologie, Medizinische Fakultat, Martin Luther Universitat Halle Wittenberg, Magdeburger Str 8, 06097, Halle Saale, Germany
    Eur J Epidemiol 25:225-30. 2010
    ..For a proper interpretation of study results, both estimated effect size and estimated precision are necessary ingredients...
  99. ncbi Plasma sex hormone concentrations and subsequent risk of breast cancer among women using postmenopausal hormones
    Shelley S Tworoger
    Channing Laboratory, Department of Medicine, Brigham and Women s Hospital and Harvard Medical School, Boston, MA 02115, USA
    J Natl Cancer Inst 97:595-602. 2005
    ....
  100. pmc Handling over-dispersion of performance indicators
    D J Spiegelhalter
    MRC Biostatistics Unit, Institute of Public Health, Cambridge CB2 2SR, UK
    Qual Saf Health Care 14:347-51. 2005
    ..A number of options for handling this phenomenon are investigated, ranging from improved risk stratification to fitting a statistical model that robustly estimates the degree of over-dispersion...
  101. ncbi Loss to follow-up in cohort studies: how much is too much?
    Vicki Kristman
    Institute for Work and Health, Toronto, Ontario, Canada
    Eur J Epidemiol 19:751-60. 2004
    ..Loss to follow-up in cohort studies rarely occurs randomly. Therefore, when planning a cohort study, one should assume that loss to follow-up is MNAR and attempt to achieve the maximum follow-up rate possible...

Research Grants63

  1. Human Papillomavirus Association with Subsets of Colorectal Cancer
    Polly A Newcomb; Fiscal Year: 2010
    ..analyses will be used to control for potential confounding variables and estimate odds ratios and 95% confidence intervals. PUBLIC HEALTH RELEVANCE: Project Narrative Colorectal cancer is the second leading cause of cancer death ..
  2. FOCUS
    JEFFREY LEE CARSON; Fiscal Year: 2011
    ..Also, this study will measure the frequency and 95% confidence intervals of the medical errors that are important in this patient population and are poorly documented in the ..
  3. Phthalates in Drugs and Male Genital Malformation
    Allen A Mitchell; Fiscal Year: 2012
    ..We will calculate odds ratios and 95% confidence intervals related to in utero exposure to medications containing phthalates...
  4. Personality and Health Services Use and Expenditures of Older Persons
    Bruce Friedman; Fiscal Year: 2010
    ..Two-part generalized linear models will be employed for expenditures. Standard errors and 95% confidence intervals will be estimated using clustered non-parametric bootstrap methods...
  5. Home ECG Monitoring to Detect Allograft Rejection Following Heart Transplantation
    Barbara J Drew; Fiscal Year: 2013
    ..Odds ratios and confidence intervals 25 will be reported, as well as established evaluative criteria for new diagnostic instruments (sensitivity,..
  6. Variation in the Safety of Back Pain-Related Surgery
    Sohail K Mirza; Fiscal Year: 2010
    ..we define as the 30-day or 1-year repeat lumbar surgery rate higher than the upper limit of SPORT 95% confidence intervals;and (2) "Overuse" we define as 4-year repeat surgery rate higher than the upper limit of the SPORT 95% ..
  7. Epidemiology, genetics, and behaviors in a study of basal cell carcinoma
    LEAH MCARTHUR FERRUCCI; Fiscal Year: 2012
    ..To identifying risk factors, I will use unconditional logistic regression to estimate odds ratios and 95% confidence intervals for the independent association of the factors of interest on BCC...
  8. Interaction of Vitamin D &Vitamin A with Lung Cancer Risk in Non-Smoking Females
    Marian L Neuhouser; Fiscal Year: 2013
    ..Logistic regression will be used to estimate multivariate-adjusted odds ratios and 95% confidence intervals for the associations of serum 25(OH) and lung cancer risk...
  9. Validating NIAAA screening guide in YCMC - administrative supplement
    Elissa R Weitzman; Fiscal Year: 2013
    ..We will use the bootstrap method of re-sampling to estimate 95% confidence intervals about each measure of sensitivity, specificity, and positive and negative predictive values;Aim 2) Evaluate ..
  10. FOCUS Data Coordinating Center
    Michael L Terrin; Fiscal Year: 2010
    ..90. Also, this study will measure the frequency and 95% confidence intervals of the medical errors that are important in this patient population...
  11. GENETIC ANALYSIS OF LUPUS AUTOIMMUNITY
    Judith James; Fiscal Year: 2000
    ..2.5. Linkage will be determined by Chi square analysis using confidence intervals of p<0.01...
  12. Migraine, Migraine Medication Use, and Risk of Breast Cancer
    Christopher I Li; Fiscal Year: 2010
    ..cases to controls, polytomous logistic regression will be used to calculate odds ratios (ORs) and 95% confidence intervals. We hypothesize that women with a history of migraine will have a reduced risk of breast cancer, and that ..
  13. The Population Genetics of Divergence
    EMANUEL HEY; Fiscal Year: 2013
    ..the likelihood, the method will provide direct acces to log-likelihood ratio tests and to likelihood-based confidence intervals. The approach will also be extended to problems in sample identification and DNA barcoding...
  14. Obesity in ovarian cancer prognosis
    Elisa V Bandera; Fiscal Year: 2012
    ..Multivariate Cox Proportional Regression methods will be used to estimate hazard ratios and 95% confidence intervals. We will also use multivariate logistic regression to evaluate the association between BMI and elevated CA-..
  15. Allergies and pancreatic cancer: A pooled analysis in PANC4
    Sara H Olson; Fiscal Year: 2010
    ..individual study results for these questions for heterogeneity and compute pooled odds ratios and 95% confidence intervals, with adjustment for study site, age, gender, and race and other potential confounding variables...
  16. Mathematical Model of Parotid Acinar Differentiation
    Grzegorz A Rempala; Fiscal Year: 2012
    ..This will allow confidence intervals to be associated with different pathways within the ODE model...
  17. Comparative Effectiveness of Two Community Based Diabetes Management Approaches
    EDWARD DEMOND SCOTT; Fiscal Year: 2013
    ..Instead, effect sizes and confidence intervals will be calculated for each domain as well as the overall test, and these results will be used for power ..
  18. Prospective Multicenter Study of Bronchiolitis Admissions: Etiology & Disposition
    Carlos A Camargo; Fiscal Year: 2010
    ..The tested discharge guidelines will be of sufficient precision based on calculated 95 percent confidence intervals to be useful when making clinical decisions...
  19. Genetic Variation of Muscle Mass
    DAVID ARTHUR BLIZARD; Fiscal Year: 2013
    ..We will utilize bioinformatics tools to nominate candidate genes when the confidence intervals for each locus has been reduced by the AIL/congenic mapping strategy...
  20. Causal inference in infectious disease prevention studies
    Michael G Hudgens; Fiscal Year: 2013
    ..Areas of particular emphasis will be development of nonparametric tests and confidence intervals, incorporating baseline covariates, and analysis of data from observational studies...
  21. Risk of Parkinson's Diseases Associated with Aspirin and Other NSAIDs
    Harvey Checkoway; Fiscal Year: 2010
    ..Relative risk estimates and 95% confidence intervals will be used as measures of association...
  22. Robust Approaches to the Development and Evaluation of Prognostic Classifiers
    Tianxi Cai; Fiscal Year: 2013
    ..In Aim 4, we focus on high dimensional regression and develop regularized resampling methods to construct confidence intervals and hypothesis testing procedures for regression coefficients and the prediction performance of estimated ..
  23. Elucidating modulators of hepatic metabolism by quantitative flux analysis
    Gregory Stephanopoulos; Fiscal Year: 2010
    ..tool, Metran, that also allows flux observability analysis and calculation of statistical properties and confidence intervals of fluxes...
  24. Hip Fracture Evaluation Alternatives of Total Hip vs Hemi-arthroplasty (HEALTH)
    Thomas A Einhorn; Fiscal Year: 2013
    ..Methodological limitations of previous studies, as well as their small sample sizes and resulting wide confidence intervals, have left the optimal operative approach unresolved...
  25. HIV/STI Risk Reduction for Incarcerated Women with Interpersonal Violence
    Caron Zlotnick; Fiscal Year: 2013
    ..We will also explore confidence intervals around preliminary differences between the enhanced WC intervention and a dose-matched control condition (..
  26. Robust Classification Methods for Categorical Regression
    Steven S Henley; Fiscal Year: 2010
    ..decision criteria (allocation rules) that trade off specificity against sensitivity, decision threshold confidence intervals, statistical tests for evaluating correct specification of posterior probabilities, statistical tests for ..
  27. Mathematical Modeling in Clinical Trials of Tuberculosis Therapeutics
    DAVID PRESTON HOLLAND; Fiscal Year: 2013
    ..rates, and use probabilistic sensitivity analysis to produce point estimates of relapse rates with 95% confidence intervals that can be used to determine which regimens are worthy of further testing...
  28. Establishing the In Vivo Threshold for Amyloid Deposition in Normal Aging
    Julie C Price; Fiscal Year: 2013
    ..The second aim will refine the PiB criteria and establish confidence intervals about the criteria that are consistent with longitudinal multi-modality neuroimaging results (i.e...
  29. Hip Fracture Evaluation Alternatives of Total Hip vs Hemi-arthroplasty (HEALTH)
    Thomas Einhorn; Fiscal Year: 2009
    ..Methodological limitations of previous studies, as well as their small sample sizes and resulting wide confidence intervals, have left the optimal operative approach unresolved...
  30. Multimodel Spaces for Robust Inference
    Steven S Henley; Fiscal Year: 2013
    ..First, an important feature of this approach is that it provides robust confidence intervals on predictions and effect sizes averaged across multiple models, which simultaneously incorporate sources ..
  31. Mammographic Density and Tissue Asymmetry Based Breast Cancer Risk Stratification
    Bin Zheng; Fiscal Year: 2013
    ..A bootstrapping method will be used to compute predictor's performance levels and 95% confidence intervals. By incorporating this risk predictor with other existing risk models, we will investigate the feasibility ..
  32. BIOSTATISTICS FOR CONNECTOMES
    William D Shannon; Fiscal Year: 2013
    ..g., hypothesis testing, regression, estimation, confidence intervals) are applied to data objects such as graphs or functions...
  33. Combined Smoking Cessation and Cognitive Processing Therapy for PTSD
    Eric Dedert; Fiscal Year: 2013
    ..b>Confidence intervals will be constructed around calculated effect sizes to reflect uncertainty regarding the reliability of the ..
  34. Methods to Compare Mechanisms of Action in Substance Use Programs
    Jason Williams; Fiscal Year: 2012
    ..of all five known contrast tests (Wald, percentile and bias-corrected bootstrap, likelihood-based confidence intervals, and a dummy latent variable test). The statistical properties (e.g...
  35. STATISTICAL ANALYSIS OF CANCER INCIDENCE
    Wenjiang Fu; Fiscal Year: 2001
    ..The methodology allows for trend estimation, construction of confidence intervals, bias correction and forecasting...
  36. Diet and Risk of Ovarian Cancer
    Ellen Chang; Fiscal Year: 2005
    ..We will use Poisson regression to estimate the relative risk (i.e. rate ratios and 95% confidence intervals) of ovarian cancer associated with specific foods, food groups, micronutrients, non-nutritive compounds, ..
  37. CESAREAN SECTION REDUCTION IN PRIMIGRAVID PATIENTS
    Fredric Frigoletto; Fiscal Year: 1993
    ..Rate ratios will be calculated and 95 % confidence intervals constructed. While this is a randomized clinical trial, confounding is still possible...
  38. THE EFFICACY OF CONJUGATE VACCINES AGAINST H INFLUENZAE
    Eugene Shapiro; Fiscal Year: 1993
    ..of the vaccine's protective efficacy will be made from the matched odds ratios with their associated 95% confidence intervals. These estimates will be adjusted for the possible effects of confounders with the use of conditional ..
  39. Drug Abuse and HIV Adherence Treatments: A Multi-Level, Comparative Meta-Analysis
    JENNIFER ELIN HETTEMA; Fiscal Year: 2013
    ..For each study included in the meta-analysis, effect sizes and 95% confidence intervals will be calculated to estimate the magnitude of HIV/AIDS, substance use, and dual focused intervention ..
  40. Metabolic and Nutritional Effects of ART in Children
    Meera Chhagan; Fiscal Year: 2009
    ..growth patterns and frequency of metabolic abnormalities following initiation of ART: means/medians and 95% confidence intervals, bivariate and multivariate logistics regression models to determine the relationship of pretreatment ..
  41. BREAST CANCER RISK--RESIDENTIAL ENVIRONMENT AND GENETICS
    Jo Freudenheim; Fiscal Year: 2001
    ..We will calculate odds ratios and 95 percents confidence intervals for distance from each category of potential exposure and for an index of probable level of exposure to ..
  42. NURSING INTERVENTIONS TO IMPROVE EPSDT UTILIZATION
    MAIJA SELBY HARRINGTON; Fiscal Year: 1993
    ..Data analysis includes logistic regression, odds ratios with confidence intervals, and z-tests...
  43. Evaluation of a biobehavioral intervention for hot flashes
    Gary R Elkins; Fiscal Year: 2010
    ..Effect sizes and confidence intervals will be calculated...
  44. Alcoholism and Suicide
    KENNETH CONNER; Fiscal Year: 2002
    ..Results will be expressed in terms of odds ratios and asymmetric confidence intervals. Goodness-of-fit will be assessed using standard procedures...
  45. Modeling STEM Workforce Dynamics Using Microsimulation &Multi-State Life Tables
    MARLENE ANN LEE; Fiscal Year: 2013
    ..S. workforce. The methods used will also produce confidence intervals around life table estimates...
  46. Frontiers in Statistical Genetics for NIAMS Researchers
    Hemant Tiwari; Fiscal Year: 2005
    ..Moreover, we propose expanding the method to allow for calculation of confidence intervals and standard errors, allowing for non-linearity in relationships, tightening the plausible boundaries of ..
  47. PathMiner: Web Telemicroscopy & Intelligent Databases
    DAVID FORAN; Fiscal Year: 2004
    ..and determine the relationship between morphologic and clinical (protein/molecular) profiles; 4) determine confidence intervals in feature space for the spectrum of malignancies; 5) develop aweb interface for PazhMiner to coordinate ..
  48. Pretest Probability Assessment for Pulmonary Embolism
    JEFFREY KLINE; Fiscal Year: 2005
    ..profile; the proportion of matched patients with an outcome of the disease in question equals the PTP; 95% confidence intervals can be computed...
  49. Clinical Meaningful Measures from Complex Designs
    A Localio; Fiscal Year: 2001
    ..treatment effect, such as risk ratios, risk differences, or number needed to treat, along with appropriate confidence intervals. Previously suggested methods for estimating relative risk and risk difference from generalized linear ..
  50. COMPUTER MAPPING OF INDUSTRIAL HYGIENE SAMPLING DATA
    Michael Symons; Fiscal Year: 1980
    ..The accuracy of this method of generalizing sampled data must be demonstrated and confidence intervals must be developed before such systems are of general utility...
  51. EPIDURAL ANESTHESIA EFFECT ON FETAL POSITION
    ELICE LIEBERMAN; Fiscal Year: 2002
    ..The position of the infant at delivery will be noted by the practitioner. Crude rate ratios and 95% confidence intervals will be calculated. Multiple logistic regression analysis will be used to adjust for confounding...
  52. RISK FACTORS FOR AMPUTATION IN DIABETIC SIOUX INDIANS
    CHRIS BURD; Fiscal Year: 1992
    ..Odds ratios with 95 per cent confidence intervals will be calculated for identified variables...
  53. MEASUREMENT ERRORS IN OCCUPATIONAL EPIDEMIOLOGY
    Donna Spiegelman; Fiscal Year: 1993
    ..general, these errors lead to bias of effect estimates toward the null and underestimation of the width of confidence intervals. Although statisticians have proposed numerous methods for treating this problem, these methods have not ..
  54. VIOLENCE AND SPONTANEOUS ABORTION IN INNER CITY WOMEN
    Deborah Nelson; Fiscal Year: 2002
    ..The primary analysis will be logistic regression, with odds ratios and 95% confidence intervals. The investigators will explore whether the effect of violence on spontaneous abortion varies with ..
  55. Bayesian Cost-Effectiveness Analysis of HIV Prevention
    Ana Johnson Masotti; Fiscal Year: 2001
    ..Existing methods for estimating confidence intervals around the cost-effectiveness ratio do not take into account parameter uncertainty and do not obviate the ..
  56. Unintentional Injury in Young Children: Exploring the Role of Adult Supervision
    PATRICIA SCHNITZER; Fiscal Year: 2009
    ..Conditional logistic regression will be used to calculate adjusted odds ratios and 95 percent confidence intervals for the association between supervision and injury in Aim 2...
  57. Comparison of Risk Factors for SIDS and Other Sudden Unexpected Deaths in Infancy
    FERN HAUCK; Fiscal Year: 2007
    ..Analyses will compare the SUDI and SIDS case infants with their respective controls; odds ratios (OR), 95% confidence intervals (Cl), and P-values will be calculated...
  58. Robust Classification Methods for Categorical Regression
    STEVEN HENLEY; Fiscal Year: 2003
    ..for classification within the context of categorical regression Moreover, the capability to estimate robust confidence intervals on decision threshold(s), compare competing classifiers, or assess the presence of classifier ..
  59. CASE-CONTROL STUDY OF RISK FACTORS FOR HIP FRACTURE
    JEANE GRISSO; Fiscal Year: 1992
    ..Univariate analysis, including calculation of odds ratios with confidence intervals, will be followed by stratification and multiple logistic regression, enabling us to evaluate the ..
  60. METHODS FOR INFERRING MOLECULAR GENALOGIES
    Joseph Felsenstein; Fiscal Year: 1991
    ..testing methods for inferring genealogies and phylogenies from molecular sequences, and methods for placing confidence intervals on those genealogies and phylogenies (henceforth called genealogies)...
  61. Plant Foods and Endometrial Cancer Epidemiology
    PAMELA HORN ROSS; Fiscal Year: 2005
    ..e., odds ratios and 95% confidence intervals) of endometrial cancer associated with the food groups, non-nutritive compounds, indices of antioxidant and ..
  62. Longitudinal Analysis for Diverse Populations
    Justine Shults; Fiscal Year: 2006
    ..of correlation models not currently implemented for generalized estimating equations (GEE) and constructing confidence intervals and tests of hypotheses for the parameters of the new structures, for data with one or more levels of ..
  63. Estimation of Unwanted Fertility
    JOHN CASTERLINE; Fiscal Year: 2007
    ..is either more accessible to a broad audience (unwanted TFRs) or more acceptable to a technical audience (confidence intervals for the two-survey estimates)...