space time clustering

Summary

Summary: A statistically significant excess of cases of a disease, occurring within a limited space-time continuum.

Top Publications

  1. ncbi Bayesian modelling of inseparable space-time variation in disease risk
    L Knorr-Held
    Institute of Statistics, Ludwig Maximilians University Munich, Ludwigstr 33, 80539 Munich, Germany
    Stat Med 19:2555-67. 2000
  2. ncbi Soft-tissue sarcoma and non-Hodgkin's lymphoma clusters around a municipal solid waste incinerator with high dioxin emission levels
    J F Viel
    Department of Public Health, Faculty of Medicine, Besancon, France
    Am J Epidemiol 152:13-9. 2000
  3. ncbi Spatial clustering of amyotrophic lateral sclerosis in Finland at place of birth and place of death
    C E Sabel
    School of Geography and Geosciences, University of St Andrews, St Andrews, United Kingdom
    Am J Epidemiol 157:898-905. 2003
  4. ncbi Spatial analysis of the distribution of leprosy in the State of Ceará, Northeast Brazil
    Ana Cláudia Dorta Montenegro
    Departamento de Saude Comunitaria, Faculdade de Medicina, Universidade Federal do Ceara, Fortaleza, CE, Brazil
    Mem Inst Oswaldo Cruz 99:683-6. 2004
  5. ncbi Analysis of the 1999-2000 highly pathogenic avian influenza (H7N1) epidemic in the main poultry-production area in northern Italy
    A Mannelli
    Dipartimento di Produzioni Animali, Epidemiologia ed Ecologia, Via Leonardo da Vinci 44, 10095 Grugliasco, Turin, Italy
    Prev Vet Med 73:273-85. 2006
  6. ncbi Spatial clustering of malaria and associated risk factors during an epidemic in a highland area of western Kenya
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 9:757-66. 2004
  7. pmc A flexibly shaped space-time scan statistic for disease outbreak detection and monitoring
    Kunihiko Takahashi
    Department of Technology Assessment and Biostatistics, National Institute of Public Health, Japan
    Int J Health Geogr 7:14. 2008
  8. pmc A model-adjusted space-time scan statistic with an application to syndromic surveillance
    K P Kleinman
    Department of Ambulatory Care and Prevention, Harvard Medical School, Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Epidemiol Infect 133:409-19. 2005
  9. ncbi Use of GIS-based spatial modeling approach to characterize the spatial patterns of malaria mosquito vector breeding habitats in northwestern Thailand
    Ratana Sithiprasasna
    Department of Entomology, US Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 34:517-28. 2003
  10. ncbi A new proposal to adjust Moran's I for population density
    R M Assunção
    Departamento de Estatística e CEDEPLAR, UFMG Universidade Federal de Minas Gerais, Caixa Postal 702, Belo Horizonte, MG 30161 970, Brazil
    Stat Med 18:2147-62. 1999

Research Grants

Detail Information

Publications170 found, 100 shown here

  1. ncbi Bayesian modelling of inseparable space-time variation in disease risk
    L Knorr-Held
    Institute of Statistics, Ludwig Maximilians University Munich, Ludwigstr 33, 80539 Munich, Germany
    Stat Med 19:2555-67. 2000
    ..Our results confirm an epidemiological hypothesis about the temporal development of the association between urbanization and risk factors for cancer...
  2. ncbi Soft-tissue sarcoma and non-Hodgkin's lymphoma clusters around a municipal solid waste incinerator with high dioxin emission levels
    J F Viel
    Department of Public Health, Faculty of Medicine, Besancon, France
    Am J Epidemiol 152:13-9. 2000
    ..g., a case-control study in which dioxins are measured in biologic tissues) before clusters of soft-tissue sarcoma and non-Hodgkin's lymphoma are ascribed to dioxin released by the municipal solid waste incinerator...
  3. ncbi Spatial clustering of amyotrophic lateral sclerosis in Finland at place of birth and place of death
    C E Sabel
    School of Geography and Geosciences, University of St Andrews, St Andrews, United Kingdom
    Am J Epidemiol 157:898-905. 2003
    ..The results demonstrate also that, if the cluster analysis is conducted at different stages of the cases' life cycle, different conclusions about where potential risk factors may exist might result...
  4. ncbi Spatial analysis of the distribution of leprosy in the State of Ceará, Northeast Brazil
    Ana Cláudia Dorta Montenegro
    Departamento de Saude Comunitaria, Faculdade de Medicina, Universidade Federal do Ceara, Fortaleza, CE, Brazil
    Mem Inst Oswaldo Cruz 99:683-6. 2004
    ....
  5. ncbi Analysis of the 1999-2000 highly pathogenic avian influenza (H7N1) epidemic in the main poultry-production area in northern Italy
    A Mannelli
    Dipartimento di Produzioni Animali, Epidemiologia ed Ecologia, Via Leonardo da Vinci 44, 10095 Grugliasco, Turin, Italy
    Prev Vet Med 73:273-85. 2006
    ..5 km from IPs. In Lombardy, IR for species other than turkeys was also relatively high...
  6. ncbi Spatial clustering of malaria and associated risk factors during an epidemic in a highland area of western Kenya
    Simon Brooker
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK
    Trop Med Int Health 9:757-66. 2004
    ..Conditional multiple logistic regression analysis showed that the risk of malaria was higher in children who were underweight, who lived at lower altitudes, and who lived in households where drugs were not kept at home...
  7. pmc A flexibly shaped space-time scan statistic for disease outbreak detection and monitoring
    Kunihiko Takahashi
    Department of Technology Assessment and Biostatistics, National Institute of Public Health, Japan
    Int J Health Geogr 7:14. 2008
    ..In particular, some spatial scan statistics are aimed at detecting irregularly shaped clusters which may not be detected by the circular spatial scan statistic...
  8. pmc A model-adjusted space-time scan statistic with an application to syndromic surveillance
    K P Kleinman
    Department of Ambulatory Care and Prevention, Harvard Medical School, Harvard Pilgrim Health Care, Boston, MA 02215, USA
    Epidemiol Infect 133:409-19. 2005
    ..The large number of days with clusters renders the census and membership approaches impractical for public health surveillance. The proposed adjustment allows practical surveillance...
  9. ncbi Use of GIS-based spatial modeling approach to characterize the spatial patterns of malaria mosquito vector breeding habitats in northwestern Thailand
    Ratana Sithiprasasna
    Department of Entomology, US Army Medical Component, Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand
    Southeast Asian J Trop Med Public Health 34:517-28. 2003
    ..These associations permit real-time monitoring and possibly forecasting of the distributions of these four species, enabling public health agencies to institute control measures before the mosquitos emerge as adults and transmit disease...
  10. ncbi A new proposal to adjust Moran's I for population density
    R M Assunção
    Departamento de Estatística e CEDEPLAR, UFMG Universidade Federal de Minas Gerais, Caixa Postal 702, Belo Horizonte, MG 30161 970, Brazil
    Stat Med 18:2147-62. 1999
    ..In this latter case, we recommend using our proposed test which is more powerful than the usual Moran's index applied directly to the rates...
  11. ncbi Space-time analysis of the dengue spreading dynamics in the 2004 Tartagal outbreak, Northern Argentina
    Camilo Rotela
    Mario Gulich Institute, Teofilo Tabanera Space Center, CONAE, Ruta C45 km8, Falda del cañete, CP 5187 Córdoba, Argentina
    Acta Trop 103:1-13. 2007
    ..The potential and limitations of remote sensing data and spatial statistics as landscape epidemiology tools for a dengue surveillance strategy and prevention are discussed...
  12. pmc Community- and individual-level socioeconomic status and breast cancer risk: multilevel modeling on Cape Cod, Massachusetts
    Thomas F Webster
    Department of Environmental Health, Boston University Schoolof Public Health, Boston, Massachusetts 02118, USA
    Environ Health Perspect 116:1125-9. 2008
    ..However, little attention has been paid to simultaneously examining both measures...
  13. pmc Effect of spatial resolution on cluster detection: a simulation study
    Al Ozonoff
    Department of Biostatistics, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA
    Int J Health Geogr 6:52. 2007
    ..Aggregation of spatial data is intended to protect privacy, but some effects of aggregation on spatial methods have not yet been quantified...
  14. ncbi Bayesian spatio-temporal analysis of joint patterns of male and female lung cancer risks in Yorkshire (UK)
    Sylvia Richardson
    Best Small Area Health Statistics Unit SAHSU, Department of Epidemiology and Public Health, Imperial College London, UK
    Stat Methods Med Res 15:385-407. 2006
    ..To do so, we use a Bayesian hierarchical model that splits the risk of disease into two spatio-temporal components: a shared component and a specific component that calibrates the differential between the two diseases...
  15. ncbi Temporal surveillance using scan statistics
    Joseph Naus
    Department of Statistics, Rutgers University of Piscataway, NJ 08854, USA
    Stat Med 25:311-24. 2006
    ..The simulations demonstrate a very high correlation between the P-scan and corresponding fixed-window GLRT...
  16. ncbi A space-time cluster investigation of an outbreak of acute respiratory disease in Norwegian cattle herds
    M Norstrom
    Department of Epidemiology, National Veterinary Institute, PO Box 8156 Dep N 0033, Oslo, Norway
    Prev Vet Med 47:107-19. 1999
    ..This study supports the hypothesis that one common source of infection was involved in the outbreaks during the study period...
  17. ncbi Space-time clusters with flexible shapes
    Vijay S Iyengar
    IBM Research Division, Thomas J Watson Research Center, Yorktown Heights, New York, USA
    MMWR Morb Mortal Wkly Rep 54:71-6. 2005
    ..Many of these approaches are based on the spatial scan statistic formulation. One key aspect of these cluster detection methods is the choice of cluster shape...
  18. ncbi Relationship of speed of slaughter on infected premises and intensity of culling of other premises to the rate of spread of the foot-and-mouth disease epidemic in Great Britain, 2001
    N Honhold
    Veterinary Epidemiology Unit, Department for Agriculture and Rural Development, Dundonald House, Upper Newtownards Road, Belfast BT4 3SB
    Vet Rec 155:287-94. 2004
    ..The intensity of culling of contiguous premises had no significant relationship in any of the three clusters...
  19. ncbi Spatial distribution of foot-and-mouth disease in Pakistan estimated using imperfect data
    Andres M Perez
    Foot and Mouth Disease Surveillance and Modeling Laboratory, Center for Animal Disease Modeling and Surveillance, Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Prev Vet Med 76:280-9. 2006
    ..8 (0.812/0.017). Areas with the highest relative probability of having an FMD outbreak were located in the Punjab region; this is a major animal-production area located along a traditional international animal-trade route...
  20. pmc The use of outbreak information in the interpretation of clustering of reported cases of Escherichia coli O157 in space and time in Alberta, Canada, 2000-2002
    D L Pearl
    Department of Population Medicine, University of Guelph, Guelph, Ontario, Canada
    Epidemiol Infect 134:699-711. 2006
    ..Our results suggest that scan statistics, based on a space-time permutation model, may have a role in outbreak investigation and surveillance programmes by identifying previously undetected outbreaks...
  21. pmc Multi-level analyses of spatial and temporal determinants for dengue infection
    Sophie O Vanwambeke
    Department of Geography, Universite Catholique de Louvain, Place Pasteur, 3, 1348 Louvain la Neuve, Belgium
    Int J Health Geogr 5:5. 2006
    ..A longitudinal study among 1750 people in two rural and one urban sites in northern Thailand from 2001 to 2003 studied spatial and temporal determinants for recent dengue infection at three levels (time, individual and household)...
  22. ncbi Reconstructing the AIDS epidemic among injection drug users in Brazil
    Mariana A Hacker
    Centro de Informação Científica e Tecnológica, Fundacao Oswaldo Cruz, Rio de Janeiro, Brazil
    Cad Saude Publica 22:751-60. 2006
    ....
  23. pmc Geographic prediction of tuberculosis clusters in Fukuoka, Japan, using the space-time scan statistic
    Daisuke Onozuka
    Department of Information Science, Fukuoka Institute of Health and Environmental Sciences, 39 Mukaizano, Dazaifu, Fukuoka 818 0135, Japan
    BMC Infect Dis 7:26. 2007
    ..Although evaluating local disease clusters leads to effective prevention and control of TB, there are few, if any, spatiotemporal comparisons for epidemic diseases...
  24. ncbi [The AIDS epidemic in Brazil, 1991-2000: space-time description]
    Antonio Luiz Rodrigues-Júnior
    Departamento de Medicina Social, Faculdade de Medicina de Ribeirao Preto, Universidade de Sao Paulo, Ribeirao Preto, SP
    Rev Soc Bras Med Trop 37:312-7. 2004
    ..The increasing number of cases reported under the category of unknown transmission showed the increased bias in measurement by the surveillance system...
  25. ncbi Epidemiology of dengue fever in Trinidad, West Indies: the outbreak of 1998
    D D Chadee
    Insect Vector Control Division, 3 Queen Street, St Joseph, Trinidad, West Indies
    Ann Trop Med Parasitol 98:305-12. 2004
  26. ncbi Evaluating spatial surveillance: detection of known outbreaks in real data
    Ken Kleinman
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, USA
    Stat Med 25:755-69. 2006
    ..They can be used to assess whether the new system works in that it detects the outbreaks better than chance would suggest and can also determine if the new systems' signals are generated earlier than an extant system...
  27. ncbi Multi-syndrome analysis of time series using PCA: a new concept for outbreak investigation
    Mojdeh Mohtashemi
    MITRE Corporation, Bedford, MA 01730, USA
    Stat Med 26:5203-24. 2007
    ....
  28. ncbi Exploring the role of auction markets in cattle movements within Great Britain
    S E Robinson
    Epidemiology Group, Department of Veterinary Clinical Sciences, Leahurst, Neston, South Wirral, UK
    Prev Vet Med 81:21-37. 2007
    ..Inclusion of network parameters, when considering the risk associated with moving cattle through auction markets may enhance the development of effective targeted disease control strategies...
  29. pmc Space-time cluster analysis of invasive meningococcal disease
    Christian J P A Hoebe
    Eastern South Limburg Municipal Public Health Service, Heerlen, The Netherlands
    Emerg Infect Dis 10:1621-6. 2004
    ..Clustering beyond chance only occurred among the closest neighboring cases (comparable to secondary cases) and was small (3.1%, 95% confidence interval 2.1%-4.1%)...
  30. ncbi Travel associated legionnaires' disease in Europe: 2003
    K Ricketts
    Health Protection Agency, CDSC, London, United Kingdom
    Euro Surveill 9:40-3. 2004
    ....
  31. ncbi Modeling a syphilis outbreak through space and time using the Bayesian maximum entropy approach
    Dionne C Gesink Law
    Epidemiology Branch, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Research Triangle Park, USA
    Ann Epidemiol 16:797-804. 2006
    ....
  32. ncbi Use of the scan statistic on disaggregated province-based data: foot-and-mouth disease in Iran
    Andres M Perez
    Foot and Mouth Disease Surveillance and Modeling Laboratory, Center for Animal Disease Modeling and Surveillance, Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Prev Vet Med 71:197-207. 2005
    ..Significant clusters of FMD were identified that coincided with roads, neighboring countries, and high-density population areas, suggesting that the region may represent a route for cross-continent transmission of FMD...
  33. ncbi Assessing surveillance using sensitivity, specificity and timeliness
    Ken P Kleinman
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, 133 Brookline Avenue, Boston, MA 02215, USA
    Stat Methods Med Res 15:445-64. 2006
    ..We also discuss the differences and under which circumstances one might prefer a given method...
  34. ncbi Joint spatial analysis of gastrointestinal infectious diseases
    Leonhard Held
    Department of Statistics, University of Munich, Ludwigstr 33, 80539 Munich, Germany
    Stat Methods Med Res 15:465-80. 2006
    ..We will illustrate our approach through the analysis of gastrointestinal diseases notification data obtained from the German infectious disease surveillance system, administered by the Robert Koch Institute in Berlin...
  35. pmc Patterns of spread and persistence of foot-and-mouth disease types A, O and Asia-1 in Turkey: a meta-population approach
    M Gilbert
    Biological Control and Spatial Ecology, Free University of Brussels, Brussels, Belgium
    Epidemiol Infect 133:537-45. 2005
    ..The pattern of persistence differed according to serotype groups and is discussed in relation to their differential affinity to cattle and small ruminant hosts...
  36. ncbi Descriptive spatial analysis of scrapie-affected flocks in Great Britain between January 1993 and December 2002
    S C Tongue
    Scrapie Epidemiology Group, Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency Weybridge, Woodham Lane, New Haw, Addlestone, Surrey KT15 3NB
    Vet Rec 159:165-70. 2006
    ....
  37. ncbi The foot-and-mouth disease epidemic in Dumfries and Galloway, 2001. 2: Serosurveillance, and efficiency and effectiveness of control procedures after the national ban on animal movements
    M Thrusfield
    Veterinary Clinical Studies, University of Edinburgh, Easter Bush Veterinary Centre, Roslin EH25 9RG
    Vet Rec 156:269-78. 2005
    ..Ultimately, there was insufficient evidence to support the effectiveness of 3 km pre-emptive culling as a control procedure...
  38. ncbi Remote sensing based identification of environmental risk factors associated with West Nile disease in horses in Camargue, France
    A Leblond
    Unité Environnement et Prévisions de la Santé des Populations, UMR CNRS 5525 TIMC, Ecole Nationale Veterinaire de Lyon, Marcy l Etoile, France
    Prev Vet Med 79:20-31. 2007
    ..The best model indicated that rice fields and dry bushes, wet "sansouire" and open water were the major components of the landscape that were associated with the presence of West Nile virus cases...
  39. ncbi Results of a postal survey of scrapie in the Shetland Islands in 2003
    S Gubbins
    Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency, New Haw, Addlestone, Surrey KT15 3NB
    Vet Rec 158:255-60. 2006
    ..The basic reproduction ratio for the spread of scrapie between flocks was estimated to be 1.47, and the mean duration of an outbreak within a flock was estimated to be approximately two years...
  40. ncbi A modelling framework to describe the spread of scrapie between sheep flocks in Great Britain
    Simon Gubbins
    Centre for Epidemiology and Risk Analysis, Veterinary Laboratories Agency, New Haw, Addlestone, Surrey KT15 3NB, UK
    Prev Vet Med 67:143-56. 2005
    ....
  41. ncbi A report of a breast cancer cluster among employees of an elementary school
    Zuber D Mulla
    Breast J 11:162-3. 2005
  42. ncbi A simple spatial model to explain the distribution of human tick-borne encephalitis cases in hungary
    Gábor R Rácz
    Department of Biology, University of New Mexico, Albuquerque, New Mexico 87131, USA
    Vector Borne Zoonotic Dis 6:369-78. 2006
    ..As a consequence of stochastic variation, meaningful patterns in the distribution of TBE cases can be only recognized when data are analyzed over broader temporal and spatial scales...
  43. ncbi Statistical inference and model selection for the 1861 Hagelloch measles epidemic
    Peter J Neal
    Department of Mathematics and Statistics, Lancaster University, Lancaster, LA1 4YF, UKP
    Biostatistics 5:249-61. 2004
    ..A reversible jump Markov chain Monte Carlo algorithm is then introduced which assists in selecting the most appropriate model to fit the data...
  44. ncbi Transmission parameters of highly pathogenic avian influenza (H7N1) among industrial poultry farms in northern Italy in 1999-2000
    A Mannelli
    Dipartimento di Produzioni Animali, Epidemiologia ed Ecologia, Via Leonardo da Vinci 44, 10095 Grugliasco TO, Italy
    Prev Vet Med 81:318-22. 2007
    ....
  45. ncbi Use of social network analysis to characterize the pattern of animal movements in the initial phases of the 2001 foot and mouth disease (FMD) epidemic in the UK
    A Ortiz-Pelaez
    Epidemiology Division, Department of Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK
    Prev Vet Med 76:40-55. 2006
    ....
  46. pmc Sexual network structure as an indicator of epidemic phase
    J J Potterat
    STD HIV Programs, El Paso County Department of Health and Environment, Colorado Springs, Colorado 80910, USA
    Sex Transm Infect 78:i152-8. 2002
    ..These observations accord with intuitive and stochastic predictions...
  47. pmc The geographical and temporal evolution of sexually transmitted disease epidemics
    G P Garnett
    Department of Infectious Disease Epidemiology, Imperial College School of Medicine, St Mary s, London, UK
    Sex Transm Infect 78:i14-9. 2002
    ..The division between high transmission probability, short duration infections and low transmission probability, long duration infections is explored...
  48. ncbi Occurrence of neural tube defects in pregnancy: an excess of cases in a 2773-km2 area in Central Italy
    Emilia Prospero
    School of Medicine, Universita Politecnica delle Marche, Piazza Roma 2 60100, Ancona, Italy
    J Toxicol Environ Health A 71:981-3. 2008
    ..The prompt gathering of data may be essential. Thus, we emphasize the need for the activation of a population-based congenital malformation registry in order to achieve a deeper understanding of these events etiology...
  49. pmc STI epidemics in the Indian Ocean region: can the phase be assessed?
    A Matteelli
    Clinic of Infectious and Tropical Diseases, University of Brescia, Italy
    Sex Transm Infect 78:i121-4. 2002
    ....
  50. ncbi Epidemiological characteristics of the 2002 outbreak of foot-and-mouth disease in the Republic of Korea
    S H Wee
    National Veterinary Research and Quarantine Service, Anyang City, Gyeonggi Do, Korea
    Transbound Emerg Dis 55:360-8. 2008
    ..Although the outbreak was a costly lesson for the Korean people, the experience gained will contribute to future efforts in the prevention and control of animal infectious diseases...
  51. ncbi A postal survey of blowfly strike occurrence in two Queensland shires
    M P Ward
    Queensland Department of Primary Industries, Animal Research Institute, Moorooka
    Aust Vet J 79:769-72. 2001
    ....
  52. ncbi Exploratory spatial analysis of Aujeszky's disease during four phases of the eradication programme in Catalonia, Spain (2003-2007)
    A Allepuz
    Centre de Recerca en Sanitat Animal, UAB IRTA, Campus de la Universitat Autonoma de Barcelona, Bellaterra, Barcelona, Spain
    Prev Vet Med 86:164-75. 2008
    ..40 farms/km(2) (median of 0.28 and standard deviation of 0.33) in clusters of sow farms that became negative and 1.51 (median of 0.70 and standard deviation of 1.61) in clusters where more sow farms became positive (p-value<0.05)...
  53. pmc Populations, pathogens, and epidemic phases: closing the gap between theory and practice in the prevention of sexually transmitted diseases
    J F Blanchard
    Department of Community Health Sciences, University of Manitoba, Winnipeg, Canada
    Sex Transm Infect 78:i183-8. 2002
    ..In addition, various approaches to the determination of epidemic phase are presented...
  54. pmc Determinants of STD epidemics: implications for phase appropriate intervention strategies
    S O Aral
    Division of STD Prevention, CDC, Atlanta, GA 30333, USA
    Sex Transm Infect 78:i3-13. 2002
    ..Globalised STD epidemics could pose a major challenge to local public health systems...
  55. ncbi Space-time interaction as an indicator of local spread during the 2001 FMD outbreak in the UK
    A Picado
    Epidemiology Division, Department of Veterinary Clinical Sciences, Royal Veterinary College, University of London, Hawkshead Lane, North Mymms, Hatfield, Hertfordshire AL9 7TA, UK
    Prev Vet Med 79:3-19. 2007
    ..Despite its limitations, our results suggest that the real-time analysis of the space-time interaction can be a valuable decision support tool during the course of a livestock disease epidemic...
  56. ncbi Quantitative estimates of the risk of new outbreaks of foot-and-mouth disease as a result of burning pyres
    R Jones
    Veterinary Laboratories Agency, Woodham Lane, Addlestone, Surrey, KT15 3NB
    Vet Rec 154:161-5. 2004
    ..However, by calculating their estimated probability of infection from the pyres it was concluded that it was unlikely that in either case the pyre was the source of infection...
  57. pmc Epidemiological characteristics of reported sporadic and outbreak cases of E. coli O157 in people from Alberta, Canada (2000-2002): methodological challenges of comparing clustered to unclustered data
    D L Pearl
    Department of Population Medicine, University of Guelph, Guelph, Ontario, Canada
    Epidemiol Infect 136:483-91. 2008
    ..Some analytical techniques, designed to account for clustering, had difficulty converging or producing realistic measures of association...
  58. pmc Geographical structures and the cholera epidemic in modern Japan: Fukushima prefecture in 1882 and 1895
    Chun Lin Kuo
    Center for Geographic Information Science, Research Center for Humanities and Social Sciences, Academia Sinica, Taipei, Taiwan
    Int J Health Geogr 6:25. 2007
    ..Text descriptions and numerical evidence culled from the reports were incorporated into a temporal-spatial study framework using geographic information system (GIS) and geo-statistical techniques...
  59. ncbi Spatio-temporal epidemiology of foot-and-mouth disease in two counties of Great Britain in 2001
    J W Wilesmith
    Epidemiology Department, Veterinary Laboratories Agency, New Haw, Addlestone, KT15 3NB Surrey, UK
    Prev Vet Med 61:157-70. 2003
    ..The interaction of disease risk in Cumbria showed that premises remained infectious for longer throughout May, June and July, consistent with delays in disease detection during this period...
  60. ncbi The Bayesian aerosol release detector: an algorithm for detecting and characterizing outbreaks caused by an atmospheric release of Bacillus anthracis
    William R Hogan
    The RODS Laboratory, Department of Biomedical Informatics, University of Pittsburgh, Pittsburgh, PA 15260, USA
    Stat Med 26:5225-52. 2007
    ..We report a proof-of-concept evaluation of BARD, which demonstrates that the approach shows promise and warrants further development and evaluation...
  61. ncbi Travel associated legionnaires' disease in Europe in 1999
    F Lever
    PHLS Communicable Disease Surveillance Centre (CDSC, London, England
    Euro Surveill 6:53-61. 2001
    ..In recent years, the work conducted by the collaborators has helped establish good surveillance and control in sites used by travellers...
  62. ncbi Detection and modelling of case clusters for urban leptospirosis
    Wagner S Tassinari
    National School of Public Health, Oswaldo Cruz Foundation, Brazilian Ministry of Health, Rio de Janeiro, Brazil
    Trop Med Int Health 13:503-12. 2008
    ....
  63. ncbi Ecology of Burkholderia pseudomallei and the interactions between environmental Burkholderia spp. and human-animal hosts
    D A Dance
    Public Health Laboratory, Derriford Hospital, Plymouth, UK
    Acta Trop 74:159-68. 2000
    ..Whether exposure to B. pseudomallei will result in disease probably depends on the balance between the virulence of the strain, the immune status of the host (e.g. diabetes mellitus) and the size of the inoculum...
  64. pmc Regional and temporal variation in methamphetamine-related incidents: applications of spatial and temporal scan statistics
    Daniel Sudakin
    Department of Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR 97331, USA
    Clin Toxicol (Phila) 47:243-7. 2009
    ..Temporal and spatial associations with regulatory interventions to reduce access to precursor chemicals (pseudoephedrine) were also explored...
  65. pmc Space-time clustering of childhood malaria at the household level: a dynamic cohort in a Mali village
    Jean Gaudart
    Medical Statistics and Informatics Research Team, LIF UMR 6166 CNRS Aix Marseille University, Faculty of Medicine, 27 Bd Jean Moulin 13385 Marseille Cedex 05, France
    BMC Public Health 6:286. 2006
    ..The aim of this study was to identify, spatially and temporally, high-risk zones of malaria, at the household level (resolution of 1 to 3 m)...
  66. ncbi Geographical distribution of optic nerve hypoplasia and septo-optic dysplasia in Northwest England
    Leena Patel
    Academic Unit of Child Health, The University of Manchester, Booth Hall Children s Hospital, Manchester, United Kingdom
    J Pediatr 148:85-8. 2006
    ..To study the distribution of septo-optic dysplasia (SOD) and optic nerve hypoplasia (ONH) in the Greater Manchester and Lancashire (GM&L) region of Northwest England, and to analyze occurrence by location and over time...
  67. ncbi Insignificant seasonal and geographical variation in incidence of biliary atresia in Japan: a regional survey of over 20 years
    Hidemi Wada
    Division of Pediatric Surgery, Kobe Children s Hospital, Kobe, Hyogo 654 0081, Japan
    J Pediatr Surg 42:2090-2. 2007
    ..Viral infection has been implicated in its etiology because of seasonality and space clustering. However, this has been controversial among whites. The present study investigates space-time clustering of the incidence of BA in Japan...
  68. ncbi Contribution of imitative suicide to the suicide rate in prisons
    Nigel McKenzie
    Camden and Islington Mental Health and Social Care Trust
    Suicide Life Threat Behav 37:538-42. 2007
    ..Model simulations with an imitation rate of 5.8% (CI 1%-11%) reproduced the observed space-time clustering...
  69. pmc Clustering of equine grass sickness cases in the United Kingdom: a study considering the effect of position-dependent reporting on the space-time K-function
    N P French
    Institute of Veterinary, Animal and Biomedical Sciences, Massey University, Palmerston North, New Zealand
    Epidemiol Infect 133:343-8. 2005
    ..of EGS does not invalidate the Monte Carlo test for space-time interaction, and find strong evidence for space time clustering of EGS cases (P < 0.001)...
  70. pmc Molecular and spatial epidemiology of cryptosporidiosis in children in a semiurban community in South India
    Sitara Swarna Rao Ajjampur
    Department of Gastrointestinal Sciences, Christian Medical College, Vellore 632 004, India
    J Clin Microbiol 45:915-20. 2007
    ..hominis in a setting where cryptosporidiosis is endemic. Molecular characterization and spatial analysis have the potential to further the understanding of disease and transmission in the community...
  71. ncbi Space-time clustering analyses of type 1 diabetes among 0- to 29-year-olds in Yorkshire, UK
    R J Q McNally
    School of Clinical Medical Sciences Child Health, University of Newcastle upon Tyne, Newcastle upon Tyne, UK
    Diabetologia 49:900-4. 2006
    ..We tested for evidence of space-time clustering among children and young adults under 30 years of age using data from a population-based register in Yorkshire, UK...
  72. ncbi The space-time clustering of highly pathogenic avian influenza (HPAI) H5N1 outbreaks in Bangladesh
    S S U Ahmed
    University of Copenhagen, Faculty of Life Sciences, Department of Large Animal Sciences, DK 1870 Frederiksberg C, Denmark
    Epidemiol Infect 138:843-52. 2010
    ..The findings are highly relevant for the successful planning and implementation of control, prevention and surveillance strategies by highlighting areas where detailed investigations should be initiated...
  73. ncbi The transmission of nosocomial pathogens in an intensive care unit: a space-time clustering and structural equation modelling approach
    S P Rushton
    Institute for Research on Environment and Sustainability, Newcastle University, Newcastle upon Tyne, Tyne and Wear NE1 7RD, UK
    Epidemiol Infect 138:915-26. 2010
    ..We suggest that isolation and bed movement as a strategy to manage MRSA infections is likely to impact upon the incidence of cases of other opportunist pathogens...
  74. pmc Spatial and space-time clustering of childhood acute leukaemia in France from 1990 to 2000: a nationwide study
    S Bellec
    INSERM U754, Hopital Paul Brousse, 94807 Villejuif Cedex, France
    Br J Cancer 94:763-70. 2006
    ..5% was evidenced for 0-4 year children living in isolated areas with more than 50 inhabitants per km(2). Cases older than 10 years living in the same area at diagnosis also tended to cluster within 6 months...
  75. pmc Space-time clustering of childhood acute lymphoblastic leukaemia: indirect evidence for a transmissible agent
    F E Alexander
    Leukaemia Research Fund Centre for Clinical Epidemiology, University of Leeds, UK
    Br J Cancer 65:589-92. 1992
    ..05). The results afford new impetus to a search for a transmissible aetiologic agent or agents; these need not be rare and the results should not be interpreted as evidence for direct case to case transmission...
  76. ncbi Cancer incidence in people with residential exposure to a municipal waste incinerator: an ecological study in Modena (Italy), 1991-2005
    Massimo Federico
    Medical Oncology II, University of Modena and Reggio Emilia, Via del Pozzo 71, Modena, Italy
    Waste Manag 30:1362-70. 2010
    ..In conclusion, bearing in mind the intrinsic limits of the study, the results suggest that there is no detectable increase of cancer risk for people living in proximity to the Modena MWI...
  77. ncbi An infectious aetiology for childhood acute leukaemia: a review of the evidence
    Richard J Q McNally
    Cancer Research UK Paediatric and Familial Cancer Research Group, Central Manchester and Manchester Children s University Hospitals NHS Trust, Manchester, UK
    Br J Haematol 127:243-63. 2004
    ....
  78. ncbi Environmental factors and childhood acute leukemias and lymphomas
    Richard J Q McNally
    School of Clinical Medical Sciences, Child Health, University of Newcastle upon Tyne, UK
    Leuk Lymphoma 47:583-98. 2006
    ..Hodgkin lymphoma (HL) is especially associated with higher levels of socioeconomic deprivation, but breast-feeding seems to confer lower risk. This is consistent with an infection or immune-response mediated etiology for HL...
  79. ncbi Host, family and community proxies for infections potentially associated with leukaemia
    Graham Richard Law
    Biostatistics Unit, Centre for Epidemiology and Biostatistics, Room 8 01, Worsley Building, University of Leeds, Leeds LS2 9LN, UK
    Radiat Prot Dosimetry 132:267-72. 2008
    ....
  80. ncbi Sheep scab outbreaks in Great Britain between 1973 and 1992: spatial and temporal patterns
    N P French
    Department of Veterinary Clinical Science and Animal Husbandry, University of Liverpool, Leahurst, Neston, UK
    Vet Parasitol 83:187-200. 1999
    ..Examination of the spatial and temporal pattern revealed strong evidence of space-time clustering (p < 0.001) and a major contribution to the pattern from very local (< 12 km) spread within 5 months of an arbitrary outbreak...
  81. ncbi Viruses and type 1 diabetes: a new look at an old story
    Maria E Craig
    School of Women s and Children s Health, University of New South Wales, Kensington, NSW, 2052, Australia
    Pediatr Diabetes 14:149-58. 2013
    ....
  82. ncbi Space-time clustering in childhood nervous system tumors in the Region of Murcia, Spain, 1998-2009
    Juan A Ortega-García
    Pediatric Environmental Health Specialty Unit, Translational Cancer Research Center, Virgen de la Arrixaca University Hospital, El Palmar, Murcia, Spain
    Childs Nerv Syst 27:1903-11. 2011
    ..The study was performed on the spatial and temporo-spatial distribution of the observed cases...
  83. pmc Enhancing spatial detection accuracy for syndromic surveillance with street level incidence data
    David J Savory
    Planned Systems International, Inc, Falls Church, VA 22041, USA
    Int J Health Geogr 9:1. 2010
    ..This study focuses on spatial detection and attempts to improve the effectiveness of the ESSENCE implementation of the spatial scan statistic by increasing the spatial resolution of incidence data from zip codes to street address level...
  84. ncbi [Impact of the flu pandemic of 1918-1919 on the general mortality profile in Boyacá, Colombia]
    Juan Manuel Ospina Díaz
    Universidad Pedagógica y Tecnológica de Colombia, Museo de Historia de la Medicina y la Salud, Antiguo Hospital San Rafael, Tunja, Boyacá, Colombia
    Hist Cienc Saude Manguinhos 16:53-81. 2009
    ..To describe the epidemiological and social impact of the flu pandemic of 1918-1919 in 41 municipalities of Boyacá, Colombia...
  85. ncbi Determinant factors for malaria transmission on the coast of Oaxaca State, the main residual transmission focus in Mexico
    Juan E Hernandez-Avila
    Department of Informatics and Geographic Medicine, National Institute of Public Health, Mexico
    Salud Publica Mex 48:405-17. 2006
    ..The purpose of this study was to investigate the influence of demographic, socioeconomic and ecological factors in malaria transmission in the most important residual transmission focus in Mexico, located in the state of Oaxaca...
  86. pmc Use of space-time models to investigate the stability of patterns of disease
    Juan Jose Abellan
    Small Area Health Statistics Unit, Department of Epidemiology and Public Health, Imperial College London, London, United Kingdom
    Environ Health Perspect 116:1111-9. 2008
    ....
  87. pmc Methodologic implications of social inequalities for analyzing health disparities in large spatiotemporal data sets: an example using breast cancer incidence data (Northern and Southern California, 1988--2002)
    Jarvis T Chen
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02215, USA
    Stat Med 27:3957-83. 2008
    ..Our approach provides a straightforward means of fitting spatiotemporal models in large data sets, while highlighting differences in spatial patterning across racial/ethnic population and across time...
  88. pmc Club drug use and dependence among young adults recruited through time-space sampling
    Jeffrey T Parsons
    Center for HIV AIDS Educational Studies and Training, New York, NY, USA
    Public Health Rep 124:246-54. 2009
    ..Yet little is known about users' demographic differences in the prevalence of club drugs. This study sought to provide a comprehensive profile of users' demographic differences in prevalence of club drug use and dependence...
  89. ncbi The CUSCORE test and the q-interval in cluster analyses of colon cancer and of lymphoma among asbestos workers
    R Chen
    Department of Epidemiology, Sackler Medical School, Tel Aviv University, Ramat Aviv, Israel
    Stat Med 22:3101-9. 2003
    ..The fact that an apparent clustering was observed from the pattern of the q-intervals leads to the conclusion that the detected clusters are real...
  90. ncbi [Breast cancer mortality in women of Southern Brazil, 1980-1999]
    Augusto Zago
    Programa de Pós Graduação em Saúde Coletiva, Universidade Católica de Santos, Santos, SP, Brasil
    Rev Saude Publica 39:641-5. 2005
    ..To analyze time and geographical trends of breast cancer mortality...
  91. ncbi Space-time clustering of childhood lymphatic leukaemias and non-Hodgkin's lymphomas in Sweden
    B Gustafsson
    Department of Paediatrics, Huddinge University Hospital, Karolinska Institutet, Stockholm, Sweden
    Eur J Epidemiol 16:1111-6. 2000
    ....
  92. pmc Space-time clustering patterns in childhood leukaemia support a role for infection
    J M Birch
    CRC Paediatric and Familial Cancer Research Group, Royal Manchester Children s Hospital, Stancliffe, UK
    Br J Cancer 82:1571-6. 2000
    ..We suggest this may be related to genetic differences in susceptibility to infection between males and females. These findings provide the basis for future studies to identify possible infectious agents...
  93. pmc Simulated anthrax attacks and syndromic surveillance
    James D Nordin
    HealthPartners Research Foundation, Minneapolis, Minnesota 55440 1524, USA
    Emerg Infect Dis 11:1394-8. 2005
    ..Timeliness and completeness of detection of events varied by rate of infection. First detection of events ranged from days 3 to 6. Similar modeling may be possible with other surveillance systems and should be a part of their evaluation...
  94. pmc A specialist leukaemia/lymphoma registry in the UK. Part 2: Clustering of Hodgkin's disease
    F E Alexander
    Leukaemia Research Fund Centre for Clinical Epidemiology, Leeds, UK
    Br J Cancer 60:948-52. 1989
    ..There is some evidence that the pattern of clustering relates to the nodular sclerosing subtype. These results are related to hypotheses of an infectious aetiology...
  95. ncbi Little or no space-time clustering found amongst cases of childhood lymphoma in North West England
    R J Q McNally
    Cancer Research UK Paediatric and Familial Cancer Research Group, Central Manchester and Manchester Children s University Hospitals NHS Trust, Manchester M27 4HA, UK
    Eur J Cancer 40:585-9. 2004
    ..There was little or no evidence for space-time clustering amongst all the lymphomas or amongst those sub-groups identified in advance...
  96. ncbi Sleeping sickness in West Africa (1906-2006): changes in spatial repartition and lessons from the past
    F Courtin
    Centre International de Recherche Développement sur l Elevage en zone Subhumide CIRDES, Institut de Recherche pour le Développement IRD UMR 177, Bobo Dioulasso, Burkina Faso
    Trop Med Int Health 13:334-44. 2008
    ..To review the geography and history of sleeping sickness (Human African trypanosomiasis; HAT) over the past 100 years in West Africa, to identify priority areas for sleeping sickness surveillance and areas where HAT no longer seems active...
  97. pmc Space-time clustering analyses of childhood acute lymphoblastic leukaemia by immunophenotype
    R J Q McNally
    Cancer Research UK Paediatric and Familial Cancer Research Group, Stancliffe, Central Manchester and Manchester Children s University Hospitals NHS Trust, Hospital Road, Manchester M27 4HA, UK
    Br J Cancer 87:513-5. 2002
    ..Significant evidence was found of space-time clustering for cases of the precursor B-cell sub-type, in the childhood peak, based on time and location at birth...
  98. ncbi [Distribution of aquatic and raptor birds in a freshwater artificial pond of Baja California Sur, Mexico]
    J A Castillo-Guerrero
    , , Apdo. Postal 19-B, La Paz, Baja California Sur, C.P. 23080,
    Rev Biol Trop 49:1131-42. 2001
    ..The site included species that usually live in freshwater and coastal areas, a characteristic reflected in their high richness. It contributes noticeably to the local avian biodiversity...
  99. ncbi An innovative land use regression model incorporating meteorology for exposure analysis
    Jason G Su
    Department of Geography, University of British Columbia, Vancouver, British Columbia, Canada V6T 1Z2
    Sci Total Environ 390:520-9. 2008
    ..The results show that, when variability in seasonal concentration measurements is present, the source area LUR or SA-LUR model is a better option for concentration estimation...
  100. ncbi [How to choose in practice a model to describe the geographic variation of cancer incidence? Example of gastrointestinal cancers from Côte-d'Or]
    S David
    Service de Biostatistiques, Bât 1M, Centre Hospitalier Lyon Sud, 165, Chemin du Grand Revoyet, 69495 Pierre Benite Cedex, France
    Rev Epidemiol Sante Publique 50:413-25. 2002
    ....
  101. ncbi Baseline and treatment effect heterogeneity for survival times between centers using a random effects accelerated failure time model with flexible error distribution
    Arnost Komarek
    Biostatistical Centre, Katholieke Universiteit Leuven, Kapucijnenvoer 35, 3000 Leuven, Belgium
    Stat Med 26:5457-72. 2007
    ..For computational convenience, the computations are based on Markov chain Monte Carlo techniques. The proposed method is illustrated on the disease-free survival times of early breast cancer patients collected in the EORTC trial 10854...

Research Grants26

  1. Case-only Cancer Clustering for Mobile Populations
    Geoffrey M Jacquez; Fiscal Year: 2010
    ..To our knowledge the techniques and software from this project will be the first to address all of these factors within a single, comprehensive framework. ..
  2. Space-Time Clustering of Non-Hodgkin's Lymphoma Using Residential Histories
    Jaymie Meliker; Fiscal Year: 2009
    ....
  3. DETECTING CLUSTERING--APPLICATION TO REPRODUCTION
    Sylvan Wallenstein; Fiscal Year: 1990
    ..We will develop methods that will facilitate the computation of critical values for Mantel's statistic based on the times and distances between pairs of events...
  4. STATISTICAL DETECTION OF CANCER CLUSTERS
    Geoffrey Jacquez; Fiscal Year: 1992
    ..CAST will serve as the software platform in the phase II research, which will determine the sensitivity of existing cluster detection techniques and develop new cluster detection methodologies...
  5. STATISTICAL DETECTION OF CANCER CLUSTERS
    Geoffrey Jacquez; Fiscal Year: 1990
    ..CANCLUS will serve as a basis for the phase II research, which will determine the sensitivity of existing cluster detection techniques and develop new cluster detection methodologies...
  6. Space-Time Clustering of Testicular Cancer Using Residential Histories
    Geoffrey Jacquez; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  7. Patterns and Contexts of Club Drug Abuse
    Jeffrey Parsons; Fiscal Year: 2007
    ..Mixed-methods strategies will be used to examine the qualitative and quantitative data together in order to further understand the data and potential implications for intervention development. ..
  8. Improving Syndromic Surveillance by Data Integration
    Alexander Ozonoff; Fiscal Year: 2007
    ..abstract_text> ..
  9. Space-Time Technology for Reconstructing Exposure in Cancer Epidemiology Studies
    Geoffrey Jacquez; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  10. SaTScan: Spatial Scan Statistic Surveillance Software
    Martin Kulldorff; Fiscal Year: 2008
    ..In this project, we propose to further develop and maintain the SaTScan software to fulfill many of these needs. ..
  11. Cancer Clustering for Residential Histories
    Geoffrey Jacquez; Fiscal Year: 2008
    ..To our knowledge the techniques and software from this project will be the first to address all of these factors within a single, comprehensive framework. [unreadable] [unreadable] [unreadable] [unreadable]..
  12. Case-only Cancer Clustering for Mobile Populations
    Geoffrey Jacquez; Fiscal Year: 2008
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  13. Risk Reduction Intervention for Highly Vulnerable Emerging Adults Males
    Jeffrey T Parsons; Fiscal Year: 2010
    ..If effective, the intervention will help minimize the negative physical and psychological effects associated with club drug use, and reduce HIV infections among emerging adult males. ..
  14. SECONDARY PREVENTION AMONG HIV POSITIVE ALCOHOL ABUSERS
    Jeffrey Parsons; Fiscal Year: 2001
    ..Participants will complete assessment batteries at intake, and at 1-week, 3, 6, 9, and 12 month follow-ups in order to assess short-term and long-term effects. ..
  15. STroodle: A GIS Foundation Class Library
    Geoffrey Jacquez; Fiscal Year: 2002
    ..Today's off-the-shelf GIS lack critical functionality required of health GIS. The Foundation Class library developed by this project will fill this need. PROPOSED COMMERCIAL APPLICATION: NOT AVAILABLE ..
  16. A Space-Time Information System for the NCI Cancer Atlas
    Geoffrey Jacquez; Fiscal Year: 2003
    ..This open-source system will be disseminated over the www, and is ultimately expected to increase our understanding of how mortality from different cancers covary, with one another, through space, and through time. ..
  17. MODEL TRANSITION SENSITIVITY ANALYSIS
    Geoffrey Jacquez; Fiscal Year: 2004
    ..The technologic and scientific innovations from this project will revolutionize our ability to formulate sound decisions regarding the analysis, control and surveillance of infectious diseases. ..
  18. IMPACT OF SEIZURE CLUSTERING ON ADULT EPILESPY
    Sheryl Haut; Fiscal Year: 2004
    ..abstract_text> ..
  19. Adherence Intervention for HIV + Alcohol Users
    Jeffrey Parsons; Fiscal Year: 2005
    ..Multivariate repeated measures analyses and growth curve modeling, using both continuous and dichotomous outcome variables, will be used to assess the impact of the intervention on both adherence and alcohol use. ..
  20. Cluster Detection Methodology for Small Area Cancer Data
    Andrew Lawson; Fiscal Year: 2005
    ..abstract_text> ..
  21. Geosocial Health Disparities: Temporal Analyses
    Jarvis Chen; Fiscal Year: 2006
    ..abstract_text> ..
  22. Cancer Cluster Morphology
    Geoffrey Jacquez; Fiscal Year: 2006
    ..unreadable] [unreadable] [unreadable] [unreadable]..
  23. Tests for Spatial Randomness in Cancer Maps
    Martin Kulldorff; Fiscal Year: 2005
    ..abstract_text> ..
  24. Data Evaluation for Early Disease Outbreak Detection
    Kenneth Kleinman; Fiscal Year: 2007
    ..abstract_text> ..
  25. Development and Evaluation of a Group HIV Intervention for Gender Stigmatized Per
    Jeffrey Parsons; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..