Genomes and Genes
Summary: The application of probability and statistical methods to calculate the risk of occurrence of any event, such as onset of illness, recurrent disease, hospitalization, disability, or death. It may include calculation of the anticipated money costs of such events and of the premiums necessary to provide for payment of such costs.
Publications239 found, 100 shown here
- An actuarial analysis shows that offering lung cancer screening as an insurance benefit would save lives at relatively low costBruce S Pyenson
Milliman, New York City, New York, USA
Health Aff (Millwood) 31:770-9. 2012..We also believe that payers and patients should demand screening from high-quality, low-cost providers, thus helping set an example of efficient system innovation...
- Actuarial analysis of private payer administrative claims data for women with endometriosisDavid Mirkin
Milliman, Inc, New York, NY 10119, USA
J Manag Care Pharm 13:262-72. 2007..Endometriosis is the most common gynecological cause of chronic pelvic pain, but published information on its associated medical care costs is scarce...
- Rationale for treating unruptured intracranial aneurysms: actuarial analysis of natural history risk versus treatment risk for coiling or clipping based on 14,050 patients in the Nationwide Inpatient Sample databaseMatthew F Lawson
Department of Neurosurgery, College of Medicine, University of Florida, Gainesville, Florida, USA
World Neurosurg 79:472-8. 2013..Our objective was to compare natural history rupture risk versus treatment risk for coiling and clipping small unruptured aneurysms using data in the Nationwide Inpatient Sample database...
- Survival of ART and amalgam restorations in permanent teeth of children after 6.3 yearsJ E Frencken
WHO Collaborating Centre for Oral Health Care Planning and Future Scenarios, Radboud University Medical Centre, College of Dental Sciences, PO Box 9101, 6500 HB Nijmegen, The Netherlands
J Dent Res 85:622-6. 2006..We concluded that the restorations produced with the ART approach, with high-viscosity glass ionomer, survived longer than those produced with the traditional approach, with amalgam, in the permanent teeth of young children...
- Eight-year experience of pediatric heart transplantation: clinical outcome using non-invasive methods for the evaluation of acute rejectionEstela Azeka
Heart Institute InCor, University of Sao Paulo Medical School, Brazil
Pediatr Transplant 6:208-13. 2002..Hence, double immunosuppression with polyclonal anti-thymocyte serum induction therapy combined with surveillance of acute rejection with non-invasive tests may provide promising clinical outcome in pediatric heart transplant recipients...
- Revision rate after artificial urinary sphincter implantation for incontinence after radical prostatectomy: actuarial analysisJ Q Clemens
Department of Urology, Northwestern University Medical School, Chicago, Illinois, USA
J Urol 166:1372-5. 2001..Despite this high reoperation rate, an excellent level of continence is maintained...
- Medtronic intact porcine bioprosthesis in the aortic position: 13-year resultsHerve Corbineau
Department of Cardiovascular and Thoracic Surgery, University Hospital Centre, Rennes, France
J Heart Valve Dis 11:537-41; discussion 541-2. 2002..This study was designed to evaluate results with this valve implanted in the aortic position at 13 years, notably with regard to the risk of structural valve deterioration (SVD)...
- The development of marked elevation in white blood cell count does not predict inferior outcome in chronic lymphocytic leukemiaJ A Silverman
University of Toronto, Ont, Canada
Leuk Lymphoma 43:1245-51. 2002..101 months, p = 0.72). We conclude that the occurrence of a WBC count > 100 x 10(9)/L in patients with CLL does not shorten the survival, and patients require therapy only if other indications for treatment are present...
- Risk-directed immunosuppression in heart transplant recipients: maintenance prednisone can be avoided in selected patientsAngelo N Arnold
Transplant Immunobiology Laboratory, Heart Transplant Program, Sentara Norfolk General Hospital, 600 Gresham Drive, Norfolk, VA 23507, USA
Transplant Proc 34:1830-3. 2002
- Prognostic factors in solitary plasmacytoma of the bone: a multicenter Rare Cancer Network studyDavid Knobel
Department of Radiation Oncology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland
BMC Cancer 6:118. 2006..Therefore, in this large retrospective study, we wanted to assess the outcome, prognostic factors, and the optimal RT dose in patients with SP...
- Behavior of oral squamous cell carcinoma in subjects with prior lichen planusAmanda A Muñoz
Department of Otolaryngology Head and Neck Surgery, Stanford University School of Medicine, Stanford, CA, USA
Otolaryngol Head Neck Surg 136:401-4. 2007..To characterize the clinical behavior of oral squamous cell carcinomas (OSCCA) arising in patients with pre-existing oral lichen planus (OLP)...
- An interinstitutional and interspecialty comparison of treatment outcome data for patients with prostate carcinoma based on predefined prognostic categories and minimum follow-upFrank A Vicini
Department of Radiation Oncology, William Beaumont Hospital, Royal Oak, Michigan, USA
Cancer 95:2126-35. 2002..The current study was conducted to compare and contrast outcomes with different forms of therapy for patients with prostate carcinoma who were treated at several institutions using predefined prognostic categories...
- Improved lung allograft function after fundoplication in patients with gastroesophageal reflux disease undergoing lung transplantationR Duane Davis
Department of Surgery, Duke University Medical Center, Durham, NC 27710, USA
J Thorac Cardiovasc Surg 125:533-42. 2003..Although alloimmune events are important, nonimmune events, such as gastroesophageal reflux, might contribute to lung injury and the development of bronchiolitis obliterans syndrome...
- Neck dissection in oral cancer--clinical review and analysis of prognostic factorsH Kokemueller
Department of Oral and Maxillofacial Surgery, Hanover Medical School, Carl Neuberg Strasse 1, 30625 Hannover, Germany
Int J Oral Maxillofac Surg 31:608-14. 2002..The comparison of neck failures after radical and modified neck dissection demonstrated a tendency to improved regional control after radical neck dissection with increasing extent of neck disease...
- Pediatric renal transplantation in a South African teaching hospital: a 20-year perspectiveG J Pitcher
Division of Pediatric Surgery, Johannesburg Hospital and the University of the Witwatersrand, Johannesburg, South Africa
Pediatr Transplant 10:441-8. 2006....
- Notes regarding confidence intervals and statistics for standardized mortality ratios and survival curves in the insurance industryDavid K Winsemius
ING Reliastar, Hartford, CT 06156, USA
J Insur Med 38:9-13. 2006..These have not seen widespread adoption in the insurance literature. This article is intended to encourage the use of these existing methods and describe other methods in the biostatistical literature...
- Selective bladder preservation by combined modality protocol treatment: long-term outcomes of 190 patients with invasive bladder cancerW U Shipley
Department of Radiation Oncology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts 02114, USA
Urology 60:62-7; discussion 67-8. 2002..To evaluate the outcomes of patients with muscle-invasive Stage T2-4a bladder carcinoma managed by transurethral surgery and concurrent chemoradiation...
- Long-term results of aortic valve replacement with Edwards Prima Plus stentless bioprosthesis: eleven years' follow upStefano Auriemma
Division of Cardiac Surgery San Bortolo Hospital, Vicenza, Italy
J Heart Valve Dis 15:691-5; discussion 695. 2006..The study aim was to evaluate late clinical outcomes after aortic valve replacement (AVR) with ELSV implanted as a miniroot in patients with aortic valve disease...
- [Ethmoid adenocarcinomas: retrospective study of 76 patients]D Stoll
C.H.U. Pellegrin, Clinique Universitaire O.R.L, , 33076 Bordeaux, France
Rev Laryngol Otol Rhinol (Bord) 122:21-9. 2001..Taking in account the involvement of the dura, sphenoid and orbit. We did not find any statistical differences between T3 patients treated by combined approach (n = 13) or by transfacial approach (n = 15)...
- Long-term outcomes after cardiac transplantation: an experience based on different eras of immunosuppressive therapyR John
Department of Surgery, Columbia University College of Physicians and Surgeons, New York, New York, USA
Ann Thorac Surg 72:440-9. 2001..Although the reasons for improvement in survival over time are multifactorial, we believe that changes in immunosuppressive therapy have had a major impact on survival as evidenced by the decreasing number of deaths due to rejection...
- Coarctation of the aorta and ventricular septal defect: should we perform a single-stage repair?Y Isomatsu
Department of Pediatric Cardiovascular Surgery, The Heart Institute of Japan, Tokyo Women s Medical University, Tokyo, Japan
J Thorac Cardiovasc Surg 122:524-8. 2001..Optimal management for coarctation of the aorta and ventricular septal defect remains controversial. The current study was undertaken to determine outcome, including recoarctation after 2-stage repair, at our institution...
- Estimating the impact on prostate cancer mortality of incorporating prostate-specific antigen testing into screeningR Whittington
Department of Radiation Oncology, Brigham and Women's Hospital and Dana Farber Cancer Institute, Boston, Massachusetts 02215, USA
Urology 58:406-10. 2001..This finding awaits validation from ongoing prospective randomized trials...
- Epithelioid sarcoma: results of conservative surgery and radiotherapyM D Callister
Department of Radiation Oncology, University of Texas M. D. Anderson Cancer Center, Houston, Texas 77030, USA
Int J Radiat Oncol Biol Phys 51:384-91. 2001..Local control with conservative surgery and RT compares favorably to published surgical series. The poor outcome for tumors > or =5 cm in size emphasizes the need for effective systemic therapy...
- Management of nasopharyngeal salivary gland malignancyV L Schramm
Center for Craniofacial-Skull Base Surgery, Denver, Colorado, USA
Laryngoscope 111:1533-44. 2001..A reliable form of vascularized reconstruction is necessary to prevent serious postoperative complications, and we currently prefer the gastro-omental free flap...
- Intrahepatic cholangiocarcinoma: resectability, recurrence pattern, and outcomesS M Weber
Hepatobiliary Service, Memorial Sloan-Kettering Cancer Center, New York, NY, USA
J Am Coll Surg 193:384-91. 2001..Although complete resection improved survival, recurrence was common. The majority of recurrences were local or regional, which may help guide future adjuvant therapy strategies...
- Stem cell transplantation for mantle cell lymphoma: should it ever be used outside clinical trials?J W Sweetenham
University of Colorado Health Sciences Center, Denver, CO 80262, USA
Bone Marrow Transplant 28:813-20. 2001..In the absence of clear evidence for a survival advantage for patients receiving stem cell transplants for mantle cell lymphoma, entry into clinical trials should be a priority...
- Comparison of late outcome after stentless versus stented xenograft aortic valve replacementG B Luciani
Division of Cardiac Surgery, University of Verona, Verona, Italy
Semin Thorac Cardiovasc Surg 13:136-42. 2001..Stentless AVR may confer selective survival advantages. Because freedom from valve failure is similar to stented xenografts, extension of stentless AVR to patients without anatomic contraindications appears justified...
- Outcome of patients undergoing radical cystectomy for invasive bladder cancerJurgen E Gschwend
Department of Urology, University of Ulm, Germany
Front Radiat Ther Oncol 36:106-17. 2002
- Metachronous second primary cancers after successful partial laryngectomy for invasive squamous cell carcinoma of the true vocal cordOllivier Laccourreye
Department of Otorhinolaryngology Head and Neck Surgery, Hopital Europeen Georges Pompidou, University of Paris V, France
Ann Otol Rhinol Laryngol 111:204-9. 2002..4% of patients who developed an MSPC (67/98) died of this disease. The 10-year actuarial survival estimates were 24% for lung MSPCs, 43.7% for non-lung, non-upper aerodigestive tract MSPCs, and 63.4% for upper aerodigestive tract MSPCs...
- Early and late results of partial left ventriculectomy: single center experience and review of the literatureRaimondo Ascione
Bristol Heart Institute, University of Bristol, Bristol, England, United Kingdom
J Card Surg 18:190-6. 2003..To evaluate early and late outcome of partial left ventriculectomy (PLV) in a single center and to conduct a review of the literature...
- Long-term results of three-dimensional conformal adjuvant and salvage radiotherapy after radical prostatectomyChristina Tsien
Department of Radiation Oncology, University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA
Urology 62:93-8. 2003..To evaluate the efficacy and toxicity of three-dimensional conformal radiotherapy (3D-CRT) in the adjuvant and salvage setting after radical prostatectomy (RP)...
- Prognostic factors of insular versus papillary/follicular thyroid carcinomaLaura Falvo
Division of General Surgery, Department of Surgical Science La Sapienza University of Rome, Rome, Italy
Am Surg 70:461-6. 2004..Our study demonstrates an unfavorable prognostic role of the insular phenotype of thyroid cancer, such that this tumor can be classified as an autonomous clinical and pathological entity...
- Long-term outcomes of the Carpentier-Edwards pericardial valve prosthesis in the aortic position: effect of patient agePaolo Biglioli
Department of Cardiac Surgery, Centro Cardiologico Fondazione Monzino IRCCS, University of Milan, Milan, Italy
J Heart Valve Dis 13:S49-51. 2004
- Surgery for acute type A aortic dissection: is advanced age a contraindication?Bruno Chiappini
Department of Cardiothoracic Surgery, St Antonius Hospital, Koekoekslaan 1, 3435 CM Nieuwegein, The Netherlands
Ann Thorac Surg 78:585-90. 2004....
- Anorexia nervosa: a 63-year population-based survival studyJohn R Iacovino
J Insur Med 36:107-10. 2004..Comparative experience over 63 years of follow-up reveals mortality ratios and excess death rates similar to those expected for the population. High-risk comorbid diagnoses of depression and alcoholism are discussed...
- Mortality in gastric cancer patients treated with gastrectomyYasushi Iwasa
Credit Suisse Life Insurance Co Ltd, Hongo MK Bldg, Hongo Bunkyo ku, Tokyo, Japan
J Insur Med 36:111-4. 2004..The results were not conclusive; although they did suggest that extended level 2 (D2) lymphadenectomy may produce better long-term mortality outcomes than less extensive surgery in some circumstances...
- [Which cancerous diseases are significant for the risk assessment when underwriting life insurance?]S Akermann
Arzteabteilung der Allianz Lebensversicherungs AG, Stuttgart
Versicherungsmedizin 57:127-32. 2005..Tumor mortality rises after age 40 and reaches its peak in males at age 70, in females the curve is moved towards higher ages and peaks at age 80...
- Assessing the likelihood of an important clinical outcome: new insights from a comparison of clinical and actuarial judgmentTim Rakow
Department of Psychology, University of Essex, Colchester, UK
Med Decis Making 25:262-82. 2005..To assess and rank the performance of different methods of predicting the probability of death following a specified surgical procedure...
- Management of papillary microcarcinoma of the thyroid glandE Orsenigo
Department of Surgery, University Vita e Salute, San Raffaele Scientific Institute, Via Olgettina, 60 20142 Milan, Italy
Eur J Surg Oncol 30:1104-6. 2004..To investigate the frequency, treatment and clinical behaviour of differentiated microcarcinoma of the thyroid gland (PTMC)...
- Impact of preoperative and postoperative atrial fibrillation on outcome after mitral valvuloplasty for nonischemic mitral regurgitationKo Bando
Department of Cardiovascular Surgery, National Cardiovascular Center, 5 7 1 Fujishirodai, Suita, Osaka 565 8565, Japan
J Thorac Cardiovasc Surg 129:1032-40. 2005..We sought to determine the impact of preoperative or postoperative atrial fibrillation on survival, stroke, and cardiac function after mitral valvuloplasty for mitral regurgitation...
- Modern surgical treatment of massive pulmonary embolism: results in 47 consecutive patients after rapid diagnosis and aggressive surgical approachMarzia Leacche
Division of Cardiac Surgery, and Cardiovascular Division, Brigham and Women s Hospital, 75 Francis Street, Boston, MA 02115, USA
J Thorac Cardiovasc Surg 129:1018-23. 2005....
- Review of survival curves for colorectal cancerCameron F E Platell
University Department of Surgery, Fremantle Hospital, Fremantle, Western Australia
Dis Colon Rectum 47:2070-5. 2004..This was to highlight some of the variation that can occur when different techniques are used to perform these calculations...
- [Twelve years' experience with Carbomedics bileaflet valves]E Bergoend
Unité de Chirurgie cardiaque, Hopital Trousseau, Tours
Arch Mal Coeur Vaiss 97:214-20. 2004..In patients over 60 years of age, the risks of long-term anticoagulant therapy should raise questions concerning the modality of follow-up and the indications. The use of biological prostheses is a possible alternative...
- Cardiac transplantation for hypertrophic cardiomyopathy: a valid therapeutic optionMarianne Coutu
Montreal Heart Institute, Research Center and Cardiovascular Division, Montreal, Quebec, Canada
J Heart Lung Transplant 23:413-7. 2004..In this report, we analyze the clinical results of cardiac transplantation in these patients...
- Conservative management of asymptomatic spinal lipomas of the conusAbhaya V Kulkarni
Service de neurochirurgie pédiatrique, Groupe Hospitalier Necker Enfants Malades, 149 rue de Sevres, 75743 Paris Cedex 15, France
Neurosurgery 54:868-73; discussion 873-5. 2004..Because of disappointing long-term results with early surgical treatment of asymptomatic children with SLCs, we have followed a protocol of conservative management for these patients. The results are presented in this report...
- Bivalvular mechanical mitral-aortic valve replacement in 254 patients: long-term results--a 22-year follow-upJean Paul Remadi
Cardiovascular Surgery Unit, G and R Läennec University Hospital, Nantes, France
Ann Thorac Surg 76:487-92. 2003..The follow-up was 22 years (1979 to 2001). The last patient was operated on 12 years before the end of the follow-up...
- Anomalous coronary artery origin from the pulmonary artery: correlation between surgical timing and left ventricular function recoveryGuido Michielon
Department of Medico Chirurgico di Cardiochirurgia e, DMCCP, Ospedale Pediatrico Bambino Gesu, Rome, Italy
Ann Thorac Surg 76:581-8; discussion 588. 2003..This study investigates the correlation between surgical timing and 15-year longitudinal left ventricular and mitral valve function, after repair of anomalous coronary artery origin from the pulmonary artery...
- [Effect of preoperative biliary drainage on the immediate and long-term results after duodeno-cephalo-pancreatectomy for peri-ampullar neoplasia]A Antinori
Dipartimento di Chirurgia, Universita Cattolica, Roma
Tumori 89:9-10. 2003..Several series have reported encouraging operative mortality and survival after resection. Controversies exist regarding the impact of preoperative biliary drainage on immediate and long-term results...
- [GIST: surgical treatment of 34 cases]R Hellies
Divisione Chirurgia Generale, Ospedale SS Trinità, ASL 8, Cagliari
Tumori 89:133-4. 2003..There was no operative mortality or morbidity. Actual survival is 67.6%. Prognostic prediction on the basis of histological findings is difficult, thus after surgery we suggest a long last follow-up...
- Long-term results of Bentall composite aortic root replacement for ascending aortic aneurysms and dissectionsSandro Gelsomino
Department of Cardiovascular Sciences, General Hospital S Maria della Misericordia, Piazzale S Maria Della Misericordia II, 33100 Udine, Italy
Chest 124:984-8. 2003..The aim of this study was to evaluate the early and long-term outcomes in patients undergoing aortic root replacement (ARR) with the Bentall procedure...
- Surgical treatment of superior sulcus tumors: results and prognostic factorsMarco Alifano
Unité de Chirurgie Thoracique, Hotel Dieu, AP HP, 1 Place du Parvis Notre Dame, 75004 Paris, France
Chest 124:996-1003. 2003..To study the clinical characteristics, treatment modalities, and outcome of patients with superior sulcus tumors who underwent surgery over a 15-year period...
- The effect of radiosurgery during management of aggressive meningiomasAnthony E Harris
Department of Neurosurgery, The Center for Image Guided Neurosurgery, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania 15213, USA
Surg Neurol 60:298-305; discussion 305. 2003..We review the local control and survival rates of patients with aggressive meningiomas after multi-modality therapy that included stereotactic radiosurgery (SRS)...
- Resection margin in patients undergoing hepatectomy for colorectal liver metastasis: a critical appraisal of the 1cm ruleZ Z R Hamady
HPB and Transplant Surgery, St James s University Hospital, Leeds, UK
Eur J Surg Oncol 32:557-63. 2006..We undertook this study to evaluate the influence of resection margin distance from metastases on survival and post-operative disease recurrence after hepatectomy for colorectal liver metastasis...
- Colorectal cancer metastases: surgical indications and multimodal approachEnrico Ciferri
Surgical Department, Genoa North Hospital, Genoa, Pontedecimo, Via Ospedale Gallino 5, 16164 Genova, Pontedecimo, Italy
Hepatogastroenterology 50:1836-46. 2003..The therapeutic plan to follow in patients affected by hepatic and pulmonary metastases from colorectal cancer is based on prognostic factors and staging...
- Long-term outcome of anastomosis leakage after curative resection for mid and low rectal cancerShih Ching Chang
Division of Colon and Rectal Surgery, Department of Surgery, National Yang Ming University, Veterans General Hospital, Taipei, Taiwan
Hepatogastroenterology 50:1898-902. 2003..The aim of this study was to evaluate the relationship of the disease recurrence and prognosis of rectal cancer with anastomosis leakage after curative low anterior resection...
- [Pediatric liver transplantation]Gustavo Varela-Fascinetto
Departamento de Trasplantes, Hospital Infantil de Mexico Federico Gomez, D F
Rev Invest Clin 57:273-82. 2005....
- Which role for radiation therapy in ethmoid cancer? A retrospective analysis of 84 cases from a single institutionStefano M Magrini
Radiation Oncology Department, Istituto del Radio O Alberti, Spedali Civili, Brescia, Italy
Tumori 90:573-8. 2004..To define the results of radiotherapy for the treatment of ethmoid carcinoma in a large, retrospective, substantially unselected series from a single institution...
- Lymphadenectomy for isolated lymph node metastasis from extremity soft-tissue sarcomasWaddah B Al-Refaie
Department of Surgical Oncology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77203 1402, USA
Cancer 112:1821-6. 2008..This study was performed to determine the outcomes of patients who underwent aggressive therapy, including lymphadenectomy in patients with LN metastasis from ESTS...
- Prognostic factors and prognostic index for chemonaïve and gemcitabine-refractory patients with advanced pancreatic cancerR Marechal
Gastroenterology Department, Gastrointestinal Cancer Unit, Erasme Hospital University, Brussels, Belgium
Oncology 73:41-51. 2007..For a few years, new chemotherapeutic agents and combinations have been under validation. The use of such treatment makes it necessary to determine factors that could predict survival time...
- [Long-term follow-up of anatomic heart transplantation. Apropos of 60 patients with a mean follow-up of 36 months]E Tatou
Service de chirurgie cardiovasculaire, CHU de Dijon, , Dijon
Arch Mal Coeur Vaiss 91:837-41. 1998..It is better to perform anatomical cardiac transplantation because of its early postsurgical advantages. Long term care is the same as in standard cardiac transplantation...
- High dose rate intracavitary brachytherapy in the treatment of nasopharyngeal carcinomaT W Leung
Insititute of Radiotherapy and Oncology, Queen Elizabeth Hospital, Kowloon, Hong Kong
Acta Oncol 35:43-7. 1996..5 Gy recurred while 5 local failures were observed among those receiving a smaller dose (p = 0.041). The general implications of these results for the treatment of NPC recurrence are discussed...
- Treatment of carcinoma of the parotid gland: the results of a multicenter studyA Tullio
Department of Maxillo-Facial Surgery, Hospital of Parma, Italy
J Oral Maxillofac Surg 59:263-70. 2001..CONCLUSIONS: Postoperative irradiation is indicated for patients with stage III and IV disease, patients with positive excision margins, and for patients with lymph node metastases...
- [Mitral valvuloplasty for asymptomatic or pauci-symptomatic mitral insufficiency]M Sousa Uva
Service de chirurgie cardiaque, , Aubervilliers
Arch Mal Coeur Vaiss 91:721-8. 1998..When performed by teams trained in techniques of mitral valvuloplasty, these results suggest that surgery should be performed early...
- Reoperation after recurrent groin hernia repairS Haapaniemi
Department of Surgery, Vrinnevi Hospital, Norrkoping, Sweden
Ann Surg 234:122-6. 2001....
- Treatment of achalasia: botulinum toxin injection vs. pneumatic balloon dilation. A prospective study with long-term follow-UpH D Allescher
Department of Internal Medicine II, Technical University of Munich, Klinikum rechts der Isar, Ismaninger Strasse 22, 81675 Munich, Germany
Endoscopy 33:1007-17. 2001..The aim of the present study was to test the effectiveness, the long-term outcome and the cumulative costs of BTX injection in consecutive patients with symptomatic achalasia in comparison with pneumatic balloon dilation...
- Outcomes following endovascular abdominal aortic aneurysm repair (EVAR): an anatomic and device-specific analysisThomas A Abbruzzese
Division of Vascular and Endovascular Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
J Vasc Surg 48:19-28. 2008..In addition, the impact of performing EVAR both within and outside of specific instructions for use (IFU) for each device was examined...
- Interleukin-6 and interferon-gamma gene polymorphisms in the development of bronchiolitis obliterans syndrome after lung transplantationKim C Lu
Department of Surgery, Washington University School of Medicine, St Louis, MO 63110, USA
Transplantation 74:1297-302. 2002..The aim of this study was to assess the effect of these genetic polymorphisms on the development of bronchiolitis obliterans syndrome (BOS) after lung transplantation...
- The effect of external pituitary irradiation on elevated serum prolactin levels in patients with pituitary macroadenomasM D Littley
Department of Endocrinology, Christie Hospital, Withington, Manchester
Q J Med 81:985-98. 1991..b>Actuarial analysis of data from all patients indicated a 50 per cent probability that prolactin would be reduced to less than ..
- Clinical experience with chronomodulated infusional 5-fluorouracil chemoradiotherapy for pancreatic adenocarcinomaKimberly S Keene
Department of Radiation Oncology, University of Virginia Health Science Center, Charlottesville, VA 22908, USA
Int J Radiat Oncol Biol Phys 62:97-103. 2005..To evaluate retrospectively the efficacy and chronic toxicities of concurrent radiotherapy and chronomodulated infusion 5-fluorouracil (5-FU) in patients with pancreatic adenocarcinoma...
- Kaplan-Meier tumor probability as a starting point for dose-response modeling provides accurate lifetime risk estimates from rodent carcinogenicity studiesW F ten Berge
DSM, Department Environment and Product Safety, Heerlen, The Netherlands
Ann N Y Acad Sci 895:112-24. 1999..It is based on an actuarial analysis of mortality and specific tumor incidence...
- Otogenic cranial base osteomyelitis: a proposed prognosis-based system for disease classificationStewart Lee
Department of Otolaryngology, The Alfred Hospital, Prahran, Victoria, Australia
Otol Neurotol 29:666-72. 2008..To review the presentation, microbiology, and long-term results of treating otogenic cranial base osteomyelitis to develop a prognosis-based disease classification system...
- Epithelioid hemangioendothelioma of soft tissue: a proposal for risk stratification based on 49 casesAndrea T Deyrup
Department of Pathology, Winship Cancer Institute, Emory University, Atlanta, GA 30308, USA
Am J Surg Pathol 32:924-7. 2008..Follow-up information was obtained for all cases. For actuarial analysis, disease-specific overall survival was evaluated using univariate and multivariable analysis...
- Various surgical modalities for trigeminal neuralgia: literature study of respective long-term outcomesM Tatli
Department of Neurosurgery, Hospital Neurologique Pierre Wertheimer Hospital, University of Lyon, Lyon, France
Acta Neurochir (Wien) 150:243-55. 2008....
- Long-term pain response and quality of life in patients with typical trigeminal neuralgia treated with gamma knife stereotactic radiosurgeryAndrew S Little
Division of Neurosurgery, Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona 85013, USA
Neurosurgery 63:915-23; discussion 923-4. 2008..We evaluated 185 patients who underwent their first GKRS treatment between 1997 and 2003 at the Barrow Neurological Institute...
- Stereotactic radiosurgery for primary trigeminal neuralgia: state of the evidence and recommendations for future reportsB C Lopez
Department of Neurosurgery, The Royal London Hospital, London, UK
J Neurol Neurosurg Psychiatry 75:1019-24. 2004..To identify systematically all the studies reporting outcomes and complications of stereotactic radiosurgery for trigeminal neuralgia and to evaluate them against predefined quality criteria...
- Creation of aorto-pulmonary window with pulmonary artery band is not good palliation for hypoplastic left heart syndromeRiad B M Hosein
Department of Cardiac Surgery, Birmingham Children s Hospital, United Kingdom
Eur J Cardiothorac Surg 32:745-50. 2007..We reviewed our experience with this technique and compared outcomes to the Norwood procedure for HLHS...
- A single-center experience of the Sorin Bicarbon heart valve prosthesis: long-term clinical, hematological and hemodynamic resultsDonald C Whitaker
Department of Cardiothoracic Surgery, University College London Hospitals, London, UK
J Heart Valve Dis 13:97-102. 2004..The Sorin Bicarbon (SB) bileaflet valve, available since 1990, has a good clinical safety profile. The study aim was to assess the long-term clinical results following implantation, plus hemodynamic and hematological aspects of the valve...
- Patterns of care and survival for patients aged under 40 years with bone sarcoma in Britain, 1980-1994C A Stiller
Childhood Cancer Research Group, University of Oxford, 57 Woodstock Road, Oxford OX2 6HJ, UK
Br J Cancer 94:22-9. 2006..Follow-up was through population registers. Survival was analysed by actuarial analysis with log-rank tests and by Cox's proportional hazards analysis...
- Longitudinal follow-up in 145 patients with medically refractory temporal lobe epilepsy treated surgically between 1984 and 1995V Salanova
Department of Neurology, Indiana University School of Medicine, Indianapolis 46202, USA
Epilepsia 40:1417-23. 1999..There are few studies of prolonged longitudinal follow-up after temporal resections...
- The effect of repair technique on postoperative right-sided obstruction in patients with truncus arteriosusJonathan M Chen
Division of Cardiothoracic Surgery, Columbia University College of Physicians and Surgeons, New York, NY, USA
J Thorac Cardiovasc Surg 129:559-68. 2005..We reviewed our experience with repair of truncus arteriosus to assess the effect of type of right ventricular outflow tract reconstruction on perioperative morbidity, survival, and freedom from catheter-based interventions and reoperation...
- [Residual shunt after percutaneous occlusion of patent ductus arteriosus by Rashkind's device. Echographic aspects, outcome, prognostic factors and management]F Godart
Service de cardiologie infantile, , CHU de Lille
Arch Mal Coeur Vaiss 87:567-72. 1994..5 cm. During follow-up, a transition between the 3 types was observed in 37% of cases. Kaplan-Meier actuarial analysis showed a residual shunt rate of 33% at one year and 19% at 2 years after implantation...
- Retrospective clinical analysis of stented vs. stentless porcine aortic bioprosthesesM Vrandecic
Biocor Institute, Avenida Alameda da Serra, 217, Bairro Vila da Serra, Belo Horizonte, 34000 000, Minas Gerais, Brazil
Eur J Cardiothorac Surg 18:46-53. 2000..The study was designed to compare hemodynamic performance, structural failure and survival of patients undergoing aortic valve replacement (AVR) with a composite aortic stented or stentless porcine bioprosthesis...
- Long-term outcome after mitral valve repair: a risk factor analysisMarie Antoinette Rey Meyer
Department of Cardiovascular Surgery, University Hospital, Lausanne, Switzerland
Eur J Cardiothorac Surg 32:301-7. 2007..In order to help perioperative decision making, we analyzed our collective to find independent risk factors affecting their outcome...
- Single photon emission computerized tomography with capromab pendetide plus computerized tomography image set co-registration independently predicts biochemical failureR J Ellis
Department of Radiation Oncology, Aultman Hospital, Canton, Ohio, USA
J Urol 179:1768-73; discussion 1773-4. 2008....
- One-year clinical results with the slow-release, polymer-based, paclitaxel-eluting TAXUS stent: the TAXUS-IV trialGregg W Stone
The Cardiovascular Research Foundation and Lenox Hill Heart and Vascular Institute, 55 E 59th St, 6th Floor, New York, NY 10022, USA
Circulation 109:1942-7. 2004..The safety and efficacy of the slow-release, polymer-based, paclitaxel-eluting stent after implantation in a broad cross section of de novo coronary lesions at 1 year are unknown...
- External beam radiotherapy for primary and adjuvant management of aggressive fibromatosisRobert A Zlotecki
Department of Radiation Oncology, Health Science Center, University of Florida College of Medicine, Gainesville, FL 32610 0385, USA
Int J Radiat Oncol Biol Phys 54:177-181. 2002....
- Better life expectancy in women with BRCA2 compared with BRCA1 mutations is attributable to lower frequency and later onset of ovarian cancerLouise M Byrd
Department of Medical Oncology, Academic Unit of Medical Genetics, St Mary s Hospital, Manchester, United Kingdom
Cancer Epidemiol Biomarkers Prev 17:1535-42. 2008..We have evaluated life expectancy using actuarial analysis and assessed the effect of breast and ovarian cancers on premature death in >1,000 BRCA1/2 carriers.
- Results of a nationwide prospective audit of stoma complications within 3 weeks of surgeryJ Cottam
Clinical Nurse Specialist Colorectal Stoma Care, Bedford Hospital, NHS Trust, Kempston Road, Bedford MK42 9DJ, UK
Colorectal Dis 9:834-8. 2007b>Actuarial analysis of stoma complications (problematic stomas) is lacking...
- Outcome of endoscopic treatment of adult postintubation tracheal stenosisS A Reza Nouraei
Department of Otolaryngology, Charing Cross Hospital, London, UK
Laryngoscope 117:1073-9. 2007..To assess the results of primary endoscopic treatment of adult postintubation tracheal stenosis, to identify predictors of a successful outcome, and better define the scope and limitations of minimally-invasive surgery for this condition...
- Actuarial versus actual freedom from structural valve deterioration with the Carpentier-Edwards porcine bioprosthesesW R Jamieson
University of British Columbia, Vancouver, British Columbia
Can J Cardiol 15:973-8. 1999..of porcine bioprostheses for valve replacement surgery has been evaluated for over three decades by actuarial analysis as the standard for reporting time-related results...
- Choice of mitral prosthesis in the elderly. An analysis of actual outcomeE A Grossi
Department of Surgery, New York University Medical Center, NY 10016, USA
Circulation 98:II116-9. 1998..Previous studies on VD in the elderly have used actuarial analysis, which overestimates the risk of VD in this population because it assumes that dead patients are still at ..
- Surgical treatment for octogenarians with lung cancer: results from a population-based series of 124 patientsHes A P Brokx
Department of Pulmonology, VU University Medical Center, Amsterdam, The Netherlands
J Thorac Oncol 2:1013-7. 2007..Previous reports on the outcome of surgery for lung cancer in octogenarians were mainly derived from single institutions. In contrast, this study presents results for all hospitals in a region of 3 million inhabitants...
- Influence of tumor necrosis factor-alpha gene-308 polymorphism on the development of coronary vasculopathy after cardiac transplantationC G Densem
Cardiothoracic Transplant Unit, Wythenshawe Hospital, United Kingdom, Manchester, UK
J Heart Lung Transplant 20:1265-73. 2001....
- Results of endoscopic surgery and intralesional steroid therapy for airway compromise due to tracheobronchial Wegener's granulomatosisS A R Nouraei
National Centre for Airway Reconstruction, Department of Ear Nose and Throat Surgery, Charing Cross Hospital, London W6 8RF, UK
Thorax 63:49-52. 2008..Upper airway compromise due to tracheobronchial stenosis commonly occurs in patients with Wegener's granulomatosis (WG). There is at present no consensus on the optimal management of this life threatening condition...
- Salvage gamma knife stereotactic radiosurgery for surgically refractory trigeminal neuralgiaAndrew S Little
Barrow Neurological Institute, St Joseph s Hospital and Medical Center, Phoenix, Arizona, USA
Int J Radiat Oncol Biol Phys 74:522-7. 2009..To evaluate the clinical outcome of patients with surgically refractory trigeminal neuralgia (TN) treated with rescue gamma knife radiosurgery (GKRS)...
- Concomitant mitral valve surgery with aortic valve replacement: a 21-year experience with a single mechanical prosthesisNiall C McGonigle
Department of Cardiac Surgery, Royal Victoria Hospital, Grosvenor Road, Belfast, UK
J Cardiothorac Surg 2:24. 2007..We consider only a single mechanical prosthesis...
- A multiarray mapping method to minimize morbidity from thermocoagulation as treatment of refractory trigeminal neuralgiaEduardo A Karol
Department of Neurosurgery, Buenos Aires University, 1428 Buenos Aires, Argentina
Surg Neurol 71:411-8; discussion 418. 2009..Conventional percutaneous thermocoagulation of postgasserian fibers has shown high success rates, with significant residual morbidity...
- A novel approach to the diagnosis and management of meralgia parestheticaS A Reza Nouraei
West London Neuroscience Centre, Charing Cross Hospital, London, United Kingdom
Neurosurgery 60:696-700; discussion 700. 2007..To review the results of conservative and surgical treatment of meralgia paresthetica (MP), with particular reference to the use of a simple clinical test for diagnosing this condition and the outcome of primary nerve decompression surgery...
- A novel polymorphism of the gene encoding furin, a TGF-beta1 activator, and the influence on cardiac allograft vasculopathy formationC G Densem
Cardiothoracic Transplant Unit, Wythenshawe Hospital, Manchester, UK
Transpl Immunol 13:185-90. 2004..We investigated for polymorphism within the promoter region of the gene for furin (fur). Allelic variation of the fur gene, in conjunction with TGF-beta1 polymorphism, was subsequently related to the development of CV...
- There is no correlation between erectile dysfunction and dose to penile bulb and neurovascular bundles following real-time low-dose-rate prostate brachytherapyAmy N Solan
Department of Radiation Oncology, Mount Sinai School of Medicine, New York, NY 10029 6574, USA
Int J Radiat Oncol Biol Phys 73:1468-74. 2009..We evaluated the relationship between the onset of erectile dysfunction and dose to the penile bulb and neurovascular bundles (NVBs) after real-time ultrasound-guided prostate brachytherapy...
- [Cushing's disease and corticotrophic adenoma: results of pituitary microsurgery]A Stevenaert
Service de Neurochirurgie, Centre Hospitalier Universitaire, Liege, France
Neurochirurgie 48:234-65. 2002..8 years (range: 0.8-12.0 years). Our longest sustained remission is 25.6 years. Actuarial analysis indicates that the probability of a patient remaining well 12 years after surgery is 80.0%. It is 86...
- REPRODUCTION AND SURVIVAL AFTER CARDIAC DEFECT REPAIRCynthia Morris; Fiscal Year: 1991..Chart review will be completed in year 2, and cases will then be prospectively identified. Actuarial analysis and the Cox proportional hazards model will determine mortality, major morbidity and their risk factors...
- BIODEMOGRAPHY OF GENETIC DISEASEBRUCE CARNES; Fiscal Year: 2003..The results derived from this award will have relevance for the estimation of lower limits to age-specific death rates, upper limits to human longevity, and forecasting life expectancy and the size of the older population. ..
- ACTION - A CHF Trial Investigating Outcomes of ExerciseGregg Fonarow; Fiscal Year: 2006..The trial will take place over 5 years with an initial 6 months for planning, training, and implementation; 3 years of enrollment; 1 year of follow-up; and 6 months for close out, analysis, and presentation. ..
- The Lee-Carter Method for Forecasting MortalityRonald Lee; Fiscal Year: 2005..Software will be produced to implement these procedures and made publicly available on a web site. Work will be closely coordinated with the Population Division of the United Nations to ensure that it meets its needs. ..
- B CLL Subtypes--Correlation with Clinical OutcomeNeil Kay; Fiscal Year: 2002....
- High Throughput Screening for Modulators of STAT5 (RMI)David Frank; Fiscal Year: 2004..The ultimate goal is the development of compounds that will act as targeted therapies for human cancers. ..
- Image Theory in Disseminating Evidence-Based PracticesPaul Falzer; Fiscal Year: 2007..abstract_text> ..
- STAT3 in the Pathogenesis and Treatment of Pancreatic CancerDavid Frank; Fiscal Year: 2007..We will test these drugs to determine whether they can be prototypes for a novel targeted form of therapy for this disease. [unreadable] [unreadable] [unreadable]..
- Extracellular Mechanisms For Thoracic Aortic AneurysmsJohn Ikonomidis; Fiscal Year: 2008..abstract_text> ..
- COGNITIVE PHENOTYPING:NEUROPSYCHIATRIC THERAPEUTICS(RMI)Robert Bilder; Fiscal Year: 2006..unreadable] [unreadable]..
- Telemedicine-Based Collaborative Care to Reduce Rural Health DisparitiesJohn C Fortney; Fiscal Year: 2010..This population is at high risk for experiencing health disparities and thus, interventions targeting this population have the potential to have a major impact. ..
- Computer Assisted Rx Education for HIV-Positives: Care+Ann Kurth; Fiscal Year: 2006..Compare outcomes: a) adherence by plasma HIV viral load and b) HIV transmission risk behaviors. Aim 3: Provide data for HIV transmission dynamics impact modeling ..
- Development of a Skin Cancer Quality of Life InsturmentJohn Rhee; Fiscal Year: 2005....
- Angiogenesis in B Chronic Lymphocytic LeukemiaNeil Kay; Fiscal Year: 2002..This latter finding would strongly suggest that maneuvers to alter the angiogenic potential in B-CLL patients would be an important and novel therapeutic approach in this disease. ..
- VEGF Function in B-CLLNeil E Kay; Fiscal Year: 2010..3) Does the VEGF/VEGF-R pathway(s) found in CLL B cells correlate with either clinical and/or critical biologic parameters in B-CLL? ..
- STAT SIGNALING IN CHRONIC LYMPHOCYTIC LEUKEMIADavid Frank; Fiscal Year: 2003..As a result of these experiments, we plan to discern the role of STATs in the abnormal growth of CLL cells, and to identify targets for novel and specific therapies. ..
- INVESTIGATING THE MECHANISMS OF PRB TUMOR SUPPRESSIONArnab Chakravarti; Fiscal Year: 2003..Specific Aim number 3: To determine whether the deregulation of E2F dependent transcription is correlated with the tumorigenic potential of RB -/- cells in-vivo. ..
- NATIONAL WILMS TUMOR STUDY -5Daniel Green; Fiscal Year: 2003..The survival of most children treated for WT allows the study of genetic and treatment factors associated with the etiology of the disease and/or the occurrence of complications of therapy. ..
- Marital Conflict and Parenting as Couples Become ParentsRenate Houts; Fiscal Year: 2004..g., personality, developmental stage of the child, gender of parents and children) of patterns of marital problem-solving and parent-child interaction. ..
- HEALTH PLAN RESPONSES TO MEDICARE HMO PREMIUM PAYMENTSRANDALL ELLIS; Fiscal Year: 2001..Results will also be useful to policy makers in understanding how recent Medicare reforms have altered HMO premiums, competition, benefit features and the resulting Medicare enrollments. ..
- LONGITUDINAL NEUROIMAGING OF FIRST EPISODE SCHIZOPHRENIARobert Bilder; Fiscal Year: 2003....