single blind method

Summary

Summary: A method in which either the observer(s) or the subject(s) is kept ignorant of the group to which the subjects are assigned.

Top Publications

  1. ncbi Blinding in randomised trials: hiding who got what
    Kenneth F Schulz
    Family Health International, PO Box 13950, Research Triangle Park, NC 27709, USA
    Lancet 359:696-700. 2002
  2. pmc Comparing standard care with a physician and pharmacist team approach for uncontrolled hypertension
    P E Bogden
    Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, USA
    J Gen Intern Med 13:740-5. 1998
  3. ncbi Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial
    Anders Heijl
    Department of Ophthalmology, Malmo University Hospital, SE 20502 Malmo, Sweden
    Arch Ophthalmol 120:1268-79. 2002
  4. ncbi Comparison of an everolimus-eluting stent and a paclitaxel-eluting stent in patients with coronary artery disease: a randomized trial
    Gregg W Stone
    Columbia University Medical Center, The Cardiovascular Research Foundation, 111 E 59th St, 11th Floor, New York, NY 10022, USA
    JAMA 299:1903-13. 2008
  5. ncbi The landscape and lexicon of blinding in randomized trials
    Kenneth F Schulz
    Family Health International, Box 13950, Research Triangle Park, NC 27709, USA
    Ann Intern Med 136:254-9. 2002
  6. ncbi Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial
    Katherine Esposito
    Center for Obesity Management, Department of Geriatrics and Metabolic Diseases, Second University of Naples, Naples, Italy
    JAMA 289:1799-804. 2003
  7. ncbi Constraint-induced movement therapy during early stroke rehabilitation
    Corwin Boake
    Department of Physical Medicine, Baylor College of Medicine University of Texas Houston Medical School, Houston, TX, USA
    Neurorehabil Neural Repair 21:14-24. 2007
  8. ncbi The therapeutic efficacy of somatic acupuncture is not increased by auriculotherapy: a randomised, blind control study in cervical myofascial pain
    Francesco Ceccherelli
    Department of Pharmacology and Anesthesiology, University of Padova, Italy
    Complement Ther Med 14:47-52. 2006
  9. pmc Effects of acupuncture and stabilising exercises as adjunct to standard treatment in pregnant women with pelvic girdle pain: randomised single blind controlled trial
    Helen Elden
    Perinatal Center, Department of Obstetrics and Gynecology, Institute for the Health of Women and Children, Sahlgrenska Academy, East Hospital, 41685 Gothenburg, Sweden
    BMJ 330:761. 2005
  10. ncbi Effect of motivational interviewing on rates of early childhood caries: a randomized trial
    Rosamund Harrison
    University of British Columbia, Oral Health Sciences, Vancouver, British Columbia
    Pediatr Dent 29:16-22. 2007

Research Grants

Detail Information

Publications209 found, 100 shown here

  1. ncbi Blinding in randomised trials: hiding who got what
    Kenneth F Schulz
    Family Health International, PO Box 13950, Research Triangle Park, NC 27709, USA
    Lancet 359:696-700. 2002
    ..Unfortunately, many articles do not contain proper reporting. If an article claims blinding without any accompanying clarification, readers should remain sceptical about its effect on bias reduction...
  2. pmc Comparing standard care with a physician and pharmacist team approach for uncontrolled hypertension
    P E Bogden
    Department of Medicine, John A. Burns School of Medicine, University of Hawaii, Honolulu, USA
    J Gen Intern Med 13:740-5. 1998
    ..CONCLUSIONS: Patients who fail to achieve national blood pressure goals under standard outpatient medical care may benefit from a program that includes a physician and pharmacist teamwork approach...
  3. ncbi Reduction of intraocular pressure and glaucoma progression: results from the Early Manifest Glaucoma Trial
    Anders Heijl
    Department of Ophthalmology, Malmo University Hospital, SE 20502 Malmo, Sweden
    Arch Ophthalmol 120:1268-79. 2002
    ..To provide the results of the Early Manifest Glaucoma Trial, which compared the effect of immediately lowering the intraocular pressure (IOP), vs no treatment or later treatment, on the progression of newly detected open-angle glaucoma...
  4. ncbi Comparison of an everolimus-eluting stent and a paclitaxel-eluting stent in patients with coronary artery disease: a randomized trial
    Gregg W Stone
    Columbia University Medical Center, The Cardiovascular Research Foundation, 111 E 59th St, 11th Floor, New York, NY 10022, USA
    JAMA 299:1903-13. 2008
    ....
  5. ncbi The landscape and lexicon of blinding in randomized trials
    Kenneth F Schulz
    Family Health International, Box 13950, Research Triangle Park, NC 27709, USA
    Ann Intern Med 136:254-9. 2002
  6. ncbi Effect of weight loss and lifestyle changes on vascular inflammatory markers in obese women: a randomized trial
    Katherine Esposito
    Center for Obesity Management, Department of Geriatrics and Metabolic Diseases, Second University of Naples, Naples, Italy
    JAMA 289:1799-804. 2003
    ..Obesity is an independent risk factor for cardiovascular disease, which may be mediated by increased secretion of proinflammatory cytokines by adipose tissue...
  7. ncbi Constraint-induced movement therapy during early stroke rehabilitation
    Corwin Boake
    Department of Physical Medicine, Baylor College of Medicine University of Texas Houston Medical School, Houston, TX, USA
    Neurorehabil Neural Repair 21:14-24. 2007
    ..Limited data are available about the effectiveness of early rehabilitation after stroke...
  8. ncbi The therapeutic efficacy of somatic acupuncture is not increased by auriculotherapy: a randomised, blind control study in cervical myofascial pain
    Francesco Ceccherelli
    Department of Pharmacology and Anesthesiology, University of Padova, Italy
    Complement Ther Med 14:47-52. 2006
    ..32 +/- 9.62 after therapy; in group B it was 38.90 +/- 15.31 and 13.43 +/- 10.96. Somatic plus auriculotherapy was therefore not statistically significantly superior to somatic therapy alone in the treatment of cervical myofascial pain...
  9. pmc Effects of acupuncture and stabilising exercises as adjunct to standard treatment in pregnant women with pelvic girdle pain: randomised single blind controlled trial
    Helen Elden
    Perinatal Center, Department of Obstetrics and Gynecology, Institute for the Health of Women and Children, Sahlgrenska Academy, East Hospital, 41685 Gothenburg, Sweden
    BMJ 330:761. 2005
    ..To compare the efficacy of standard treatment, standard treatment plus acupuncture, and standard treatment plus stabilising exercises for pelvic girdle pain during pregnancy...
  10. ncbi Effect of motivational interviewing on rates of early childhood caries: a randomized trial
    Rosamund Harrison
    University of British Columbia, Oral Health Sciences, Vancouver, British Columbia
    Pediatr Dent 29:16-22. 2007
    ..The purposes of this randomized controlled trial were to: (1) test motivational interviewing (MI) to prevent early childhood caries; and (2) use Poisson regression for data analysis...
  11. ncbi Effects of exercise on depressive symptoms in older adults with poorly responsive depressive disorder: randomised controlled trial
    Anne S Mather
    Section of Ageing and Health, Department of Medicine, University of Dundee, Ninewells Hospital and Medical School, Dundee DD1 9SY, Scotland, UK
    Br J Psychiatry 180:411-5. 2002
    ..Depression is common in later life...
  12. ncbi The favorable effect of regional citrate anticoagulation on interleukin-1beta release is dissociated from both coagulation and complement activation
    Luca Gabutti
    Division of Nephrology, Department of Internal Medicine, Carità Hospital, Locarno, Switzerland
    J Nephrol 17:819-25. 2004
    ..This study aimed to verify whether the favorable effect of RCA on biocompatibility is independent from coagulation pathway modulation...
  13. ncbi Special low-protein foods ameliorate postprandial off in patients with advanced Parkinson's disease
    Michela Barichella
    Clinical Nutrition Unit, Istituti Clinici di Perfezionamento, Milan, Italy
    Mov Disord 21:1682-7. 2006
    ..8%) was observed. Consumption of LPP in the first part of the day ameliorates off periods in PD patients, but additional studies including pharmacokinetics are needed...
  14. ncbi Views of service users and providers on joint crisis plans: single blind randomized controlled trial
    Claire Henderson
    P029, Health Service and Population Research Dept, Institute of Psychiatry, King s College London, De Crespigny Park, London SE5 8AF UK
    Soc Psychiatry Psychiatr Epidemiol 44:369-76. 2009
    ..We report participants' and case managers' use of and views on the value of Joint Crisis Plans (JCPs), shown to reduce compulsory hospitalisation and violence...
  15. ncbi Knee joint loading differs in individuals with mild compared with moderate medial knee osteoarthritis
    Laura E Thorp
    Rush University Medical Center, Chicago, Illinois 60612, USA
    Arthritis Rheum 54:3842-9. 2006
    ....
  16. ncbi Underreporting exacerbation of chronic obstructive pulmonary disease in a longitudinal cohort
    Lisa Langsetmo
    Respiratory Epidemiology and Clinical Research Unit, Montreal Chest Institute, 3650 St Urbain, Montreal, PQ, Canada
    Am J Respir Crit Care Med 177:396-401. 2008
    ..Unreported exacerbations and failure to seek medical attention may have consequences on the health of patients with chronic obstructive pulmonary disease...
  17. pmc Effect of joint crisis plans on use of compulsory treatment in psychiatry: single blind randomised controlled trial
    Claire Henderson
    Health Services Research Department, Institute of Psychiatry, King s College London, London SE5 8AF
    BMJ 329:136. 2004
    ..To investigate whether a form of advance agreement for people with severe mental illness can reduce the use of inpatient services and compulsory admission or treatment...
  18. ncbi Pharmacokinetics, pharmacodynamics, and safety of exenatide in patients with type 2 diabetes mellitus
    Orville G Kolterman
    Amylin Pharmaceuticals Inc, 9360 Towne Centre Drive, Suite 110, San Diego, CA 92121, USA
    Am J Health Syst Pharm 62:173-81. 2005
    ..The pharmacology and tolerability of exenatide in patients with type 2 diabetes mellitus were studied...
  19. ncbi Randomized clinical trial of therapeutic exercise in subacute stroke
    Pamela Duncan
    University of Florida Brooks Center for Rehabilitation Studies and the Department of Veteran Affairs Rehabilitation Outcomes Center, Gainesville 32610, USA
    Stroke 34:2173-80. 2003
    ..The objective of this study was to determine whether a structured, progressive, physiologically based exercise program for subacute stroke produces gains greater than those attributable to spontaneous recovery and usual care...
  20. ncbi Comparison of mydriatic efficacy of spray application and drop instillation of tropicamide 1%
    A Akman
    Baskent University Faculty of Medicine, Department of Ophthalmology, Ankara, Turkey
    Eye (Lond) 13:653-5. 1999
    ..To determine whether the mydriatic efficacy of spray application of tropicamide 1% is comparable to drop instillation of tropicamide 1%, and to compare the ocular discomfort caused by these methods...
  21. ncbi Comparison of a computer based method and the classical manual method for radiographic joint space width assessment in hip osteoarthritis
    Jean Francis Maillefert
    Rene Descartes University, Institute of Rheumatology, Paris, France
    J Rheumatol 29:2592-6. 2002
    ..To compare the intraobserver reliability and the sensitivity to change of 2 techniques evaluating the cartilage breakdown in hip osteoarthritis (OA)...
  22. ncbi Effect of additional functional exercises on balance in elderly people
    Eling D de Bruin
    Institute of Human Movement Sciences and Sport, D Biology, ETH Zurich and Department of Rheumatology and Institute of Physical Medicine, University Hospital Zurich, Switzerland
    Clin Rehabil 21:112-21. 2007
    ..To evaluate the additional effect of functional exercises on balance and lower extremity function among hostel-dwelling elderly people partaking in strength,training...
  23. pmc Community based occupational therapy for patients with dementia and their care givers: randomised controlled trial
    Maud J L Graff
    Research Group for Allied Health Care, Department of Allied Health Care Disciplines, Occupational Therapy, University Medical Center Nijmegen, PO Box 9101, 6500 HB Nijmegen, Netherlands
    BMJ 333:1196. 2006
    ..To determine the effectiveness of community based occupational therapy on daily functioning of patients with dementia and the sense of competence of their care givers...
  24. ncbi Physical exercise and the prevention of disability in activities of daily living in older persons with osteoarthritis
    B W Penninx
    Sticht Center on Aging, Wake Forest University School of Medicine, Medical Center Boulevard, Winston Salem, NC 27157, USA
    Arch Intern Med 161:2309-16. 2001
    ..However, proved preventive strategies for ADL disability are lacking. A sedentary lifestyle is an important cause of disability. This study examines whether an exercise program can prevent ADL disability...
  25. ncbi Botulinum toxin type A for migraine prophylaxis in the Japanese population: an open-label prospective trial
    Kosuke Suzuki
    Department of Neurology, School of Medicine, Kitasato University, Sagamihara
    Intern Med 46:959-63. 2007
    ..To evaluate the efficacy and tolerability of Botulinum Toxin Type A (BoNT-A) for migraine prophylaxis...
  26. ncbi Decrease of pregnant women's pelvic pain after acupuncture: a randomized controlled single-blind study
    Irene Lund
    Department of Physiology and Pharmacology, Karolinska Institutet, SE 171 77 Stockholm, Sweden
    Acta Obstet Gynecol Scand 85:12-9. 2006
    ..Our aim was to evaluate the effects of two different acupuncture stimulation modes on pelvic pain intensity and some emotional symptoms due to the pain condition...
  27. ncbi Cost-effectiveness of screening and referral to an alcohol health worker in alcohol misusing patients attending an accident and emergency department: a decision-making approach
    Barbara Barrett
    King s College London, Institute of Psychiatry, Box P024, De Crespigny Park, London SE5 8AF, UK
    Drug Alcohol Depend 81:47-54. 2006
    ....
  28. ncbi Balance, mobility, and falls among community-dwelling elderly persons: effects of a rehabilitation exercise program
    Kevin M Means
    Department of Physical Medicine and Rehabilitation, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
    Am J Phys Med Rehabil 84:238-50. 2005
    ..To assess the short-term effect of an exercise-based rehabilitation intervention on balance, mobility, falls and injuries...
  29. ncbi A 14-week, randomized, double-blinded, placebo-controlled monotherapy trial of pregabalin in patients with fibromyalgia
    Lesley M Arnold
    University of Cincinnati College of Medicine, Cincinnati, Ohio 45219, USA
    J Pain 9:792-805. 2008
    ..Compared with placebo, all 3 doses of pregabalin were associated with significant improvement in sleep. The most commonly reported pregabalin-related adverse events were dizziness and somnolence, which tended to be dose-related...
  30. ncbi Duration of protection with RTS,S/AS02A malaria vaccine in prevention of Plasmodium falciparum disease in Mozambican children: single-blind extended follow-up of a randomised controlled trial
    Pedro L Alonso
    Centre de Salut Internacional, Hospital Clinic Institut d Investigacions Biomediques August Pi i Sunyer, Universitat de Barcelona, Villarroel 170, 08036 Barcelona, Spain
    Lancet 366:2012-8. 2005
    ..An important remaining issue is the durability of protection against clinical disease in these children...
  31. ncbi Combination therapy for uncomplicated falciparum malaria in Ugandan children: a randomized trial
    Grant Dorsey
    Department of Medicine, San Francisco General Hospital, University of California, San Francisco, CA 94143, USA
    JAMA 297:2210-9. 2007
    ..Combination therapy is now widely advocated as first-line treatment for uncomplicated malaria in Africa. However, it is not clear which treatment regimens are optimal or how to best assess comparative efficacies in highly endemic areas...
  32. ncbi Circuit class therapy versus individual physiotherapy sessions during inpatient stroke rehabilitation: a controlled trial
    Coralie K English
    School of Health Sciences, University of South Australia, Adelaide, South Australia
    Arch Phys Med Rehabil 88:955-63. 2007
    ..To compare the effectiveness of circuit class therapy and individual physiotherapy (PT) sessions in improving walking ability and functional balance for people recovering from stroke...
  33. ncbi Telmisartan plus HCTZ vs. amlodipine plus HCTZ in older patients with systolic hypertension: results from a large ambulatory blood pressure monitoring study
    Steen Neldam
    Rodøvre Centrum, Denmark
    Am J Geriatr Cardiol 15:151-60. 2006
    ..0175). Adverse events (41.2% and 53.7%, respectively) and discontinuations (5.0% and 11.3%, respectively) were lower (p<0.0001) with telmisartan than with amlodipine, mainly due to peripheral edema (1.2% and 24.3%, respectively)...
  34. ncbi A multicenter, 14-week study of telmisartan and ramipril in patients with mild-to-moderate hypertension using ambulatory blood pressure monitoring
    Yves Lacourciere
    Hypertension Research Unit, CHUL, Centre Hospitalier Universitaire de Quebec, 2705 boulevard Laurier S 135, Sainte Foy, Quebec, QC G1V 4G2, Canada
    Am J Hypertens 19:104-12. 2006
    ....
  35. ncbi Meta-analysis of 24-hour intraocular pressure studies evaluating the efficacy of glaucoma medicines
    William C Stewart
    PRN Pharmaceutical Research Network, LLC, Dallas, Texas, USA
    Ophthalmology 115:1117-1122.e1. 2008
    ....
  36. pmc UVB phototherapy in an outpatient setting or at home: a pragmatic randomised single-blind trial designed to settle the discussion. The PLUTO study
    Mayke B G Koek
    Department of Dermatology Allergology G02 124, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    BMC Med Res Methodol 6:39. 2006
    ..Thus, firm evidence to support or discourage the use of home UVB phototherapy has not yet been obtained. This is the goal of the present study, the PLUTO study (Dutch acronym for "national trial on home UVB phototherapy for psoriasis")...
  37. pmc Exercise and manual auricular acupuncture: a pilot assessor-blind randomised controlled trial. (The acupuncture and personalised exercise programme (APEP) trial)
    S M McDonough
    Health and Rehabilitation Sciences Research Institute and School of Health Sciences, University of Ulster, Jordanstown, Northern Ireland, UK
    BMC Musculoskelet Disord 9:31. 2008
    ..It may be a useful adjunct to exercise in managing CLBP; however, there is only limited evidence to support its use with this patient group...
  38. pmc Foot orthoses and physiotherapy in the treatment of patellofemoral pain syndrome: a randomised clinical trial
    Bill Vicenzino
    Division of Physiotherapy, School of Health and Rehabilitation Sciences, University of Queensland, Brisbane, Australia
    BMC Musculoskelet Disord 9:27. 2008
    ..Although foot orthoses are a commonly used intervention for patellofemoral pain syndrome, only two pilot studies with short term follow up have been conducted into their clinical efficacy...
  39. ncbi The prospective, randomized investigation of the safety and efficacy of telmisartan versus ramipril using ambulatory blood pressure monitoring (PRISMA I)
    Bryan Williams
    Department of Cardiovascular Sciences, University of Leicester School of Medicine, Leicester, UK
    J Hypertens 24:193-200. 2006
    ..To compare the efficacy and safety of once-daily telmisartan and ramipril on blood pressure (BP) reductions during the last 6 h of the dosing interval...
  40. ncbi Endoscopic full-thickness plication for the treatment of gastroesophageal reflux disease: A randomized, sham-controlled trial
    Richard Rothstein
    Section of Gastroenterology and Hepatology, Dartmouth Hitchcock Medical Center, Lebanon, New Hampshire 03756, USA
    Gastroenterology 131:704-12. 2006
    ..The aim of this study was to determine the effectiveness of endoscopic full-thickness plication for the treatment of gastroesophageal reflux disease (GERD) in comparison with a sham procedure...
  41. ncbi Effect of constraint-induced movement therapy on upper extremity function 3 to 9 months after stroke: the EXCITE randomized clinical trial
    Steven L Wolf
    Department of Rehabilitation Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA
    JAMA 296:2095-104. 2006
    ....
  42. pmc Comparison of laparoscopic and mini incision open donor nephrectomy: single blind, randomised controlled clinical trial
    Niels F M Kok
    Department of Surgery, Erasmus MC, PO Box 2040, 3000 CA Rotterdam, Netherlands
    BMJ 333:221. 2006
    ..To determine the best approach for live donor nephrectomy to minimise discomfort to the donor and to provide good graft function...
  43. ncbi A comparison of citalopram and paroxetine in the treatment of panic disorder: a randomized, single-blind study
    G Perna
    Department of Neuropsychiatric Sciences, University Vita e Salute, Istituto Scientifico Ospedale San Raffaele, Milan, Italy
    Pharmacopsychiatry 34:85-90. 2001
    ..In this class of drugs, citalopram is the most selective for serotonin. We compared these two drugs and their effectiveness and tolerability in a sample of patients with PD in a two-month treatment course...
  44. pmc Diurnal IOP control with bimatoprost versus latanoprost in exfoliative glaucoma: a crossover, observer-masked, three-centre study
    A G P Konstas
    Glaucoma Unit, A University Department of Ophthalmology, AHEPA Hospital, 1 Kyriakidi Str, Thessaloniki 546 36, Greece
    Br J Ophthalmol 91:757-60. 2007
    ..To evaluate the diurnal intraocular pressure (IOP) control and safety of bimatoprost versus latanoprost in exfoliative glaucoma (XFG)...
  45. ncbi Crystalloid or colloid fluid loading and pulmonary permeability, edema, and injury in septic and nonseptic critically ill patients with hypovolemia
    Melanie van der Heijden
    Department of Intensive Care, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands
    Crit Care Med 37:1275-81. 2009
    ..We hypothesized that 1) crystalloid loading results in more edema formation than colloid loading and 2) the differences among the types of fluid decreases at high permeability...
  46. pmc Effects of self-management, education and specific exercises, delivered by health professionals, in patients with osteoarthritis of the knee
    S Coleman
    Arthritis Foundation of Western Australia, PO Box 34, Wembley, Western Australia, 6914, Australia
    BMC Musculoskelet Disord 9:133. 2008
    ....
  47. pmc Community occupational therapy for older patients with dementia and their care givers: cost effectiveness study
    Maud J L Graff
    Alzheimer Centre Nijmegen, Department of Occupational Therapy 897, Radboud University Nijmegen Medical Centre, PO Box 9101, 6500 HB Nijmegen, Netherlands
    BMJ 336:134-8. 2008
    ..To assess the cost effectiveness of community based occupational therapy compared with usual care in older patients with dementia and their care givers from a societal viewpoint...
  48. pmc Diagnostic value of antibodies against a modified citrullinated vimentin in rheumatoid arthritis
    Christian Dejaco
    Clinical Department of Internal Medicine, Division of General Internal Medicine, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Arthritis Res Ther 8:R119. 2006
    ..In the high-specificity range, however, the anti-CCP2 assay appears to be superior to the anti-MCV test...
  49. pmc Joint crisis plans for people with psychosis: economic evaluation of a randomised controlled trial
    Chris Flood
    Department of Mental Health and Learning Disability, City University, London E1 2EA
    BMJ 333:729. 2006
    ..To investigate the cost effectiveness of joint crisis plans, a form of advance agreement for people with severe mental illness...
  50. ncbi The effectiveness of exercise therapy in patients with osteoarthritis of the hip or knee: a randomized clinical trial
    M E van Baar
    Netherlands Institute of Primary Health Care, Utrecht
    J Rheumatol 25:2432-9. 1998
    ..To determine the effectiveness of exercise therapy in patients with osteoarthritis (OA) of the hip or knee...
  51. pmc Efficacy of knee tape in the management of osteoarthritis of the knee: blinded randomised controlled trial
    Rana S Hinman
    Centre for Sports Medicine Research and Education, School of Physiotherapy, University of Melbourne, Victoria, 3010, Australia
    BMJ 327:135. 2003
    ..To test the hypotheses that therapeutic taping of the knee improves pain and disability in patients with osteoarthritis of the knee and that benefits remain after stopping treatment...
  52. ncbi Benefits of cognitive-motor intervention in MCI and mild to moderate Alzheimer disease
    J Olazaran
    Fundación Maria Wolff, Madrid, Spain
    Neurology 63:2348-53. 2004
    ..To evaluate the efficacy of a cognitive-motor program in patients with early Alzheimer disease (AD) who are treated with a cholinesterase inhibitor (ChEI)...
  53. ncbi Weight loss reduces knee-joint loads in overweight and obese older adults with knee osteoarthritis
    Stephen P Messier
    Snow Biomechanics Laboratory, Department of Health and Exercise Science, Wake Forest University, Winston Salem, North Carolina 27109, USA
    Arthritis Rheum 52:2026-32. 2005
    ..To determine the relationship between change in body mass and knee-joint moments and forces during walking in overweight and obese older adults with knee osteoarthritis (OA) following an 18-month clinical trial of diet and exercise...
  54. pmc A community-based fitness and mobility exercise program for older adults with chronic stroke: a randomized, controlled trial
    Marco Y C Pang
    School of Rehabilitation Sciences, University of British Columbia, Vancouver, British Columbia, Canada
    J Am Geriatr Soc 53:1667-74. 2005
    ..To examine the effects of a community-based group exercise program for older individuals with chronic stroke...
  55. ncbi Brain imaging of the effects of lidocaine on tinnitus
    Samuel A Reyes
    Department of Communicative Disorders and Sciences, State University of New York at Buffalo, Buffalo, NY 14214, USA
    Hear Res 171:43-50. 2002
    ..In addition, generalized lidocaine effects were found in the basal ganglia, thalamus, and a region spanning the Rolandic fissure...
  56. pmc Single blind, randomised, comparative study of the Bug Buster kit and over the counter pediculicide treatments against head lice in the United Kingdom
    N Hill
    Department of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London WC1E 7HT
    BMJ 331:384-7. 2005
    ..To compare the effectiveness of the Bug Buster kit with a single treatment of over the counter pediculicides for eliminating head lice...
  57. ncbi Effectiveness of loaded sit-to-stand resistance exercise for children with mild spastic diplegia: a randomized clinical trial
    Hua fang Liao
    School and Graduate Institute of Physical Therapy, College of Medicine, National Taiwan University, Taipei, Taiwan
    Arch Phys Med Rehabil 88:25-31. 2007
    ..To investigate effectiveness of a functional strengthening program, the loaded sit-to-stand (STS) resistance exercise, for children with cerebral palsy (CP)...
  58. pmc Study to prospectively evaluate reamed intramedually nails in patients with tibial fractures (S.P.R.I.N.T.): study rationale and design
    Mohit Bhandari
    SPRINT Methods Center, Department of Clinical Epidemiology and Biostatistics, 1200 Main Street West, Room 2C9 Hamilton, Ontario, Canada
    BMC Musculoskelet Disord 9:91. 2008
    ....
  59. ncbi Physiotherapy for patients with mobility problems more than 1 year after stroke: a randomised controlled trial
    John Green
    Rehabilitation Services, Bradford Community NHS Trust, Bradford, UK
    Lancet 359:199-203. 2002
    ..Community physiotherapy is often prescribed for stroke patients with long-term mobility problems. We aimed to assess the effectiveness of this treatment in patients who had mobility problems 1 year after stroke...
  60. ncbi Reduced incidence of intraoperative complications in a multicenter controlled clinical trial of triamcinolone in vitrectomy
    Keita Yamakiri
    Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Science, Kagoshima, Japan
    Ophthalmology 114:289-96. 2007
    ..To evaluate the benefits and potential complications of using triamcinolone acetonide (TA) in pars plana vitrectomy (PPV)...
  61. ncbi Low-energy extracorporeal shock-wave treatment (ESWT) for tendinitis of the supraspinatus. A prospective, randomised study
    J Schmitt
    Department of Orthopaedics, Philipps-University, Marburg, Germany
    J Bone Joint Surg Br 83:873-6. 2001
    ..001). Statistical analysis showed no difference between the groups for the Constant score and for pain. We therefore do not recommend ESWT for the treatment of tendinitis of supraspinatus...
  62. ncbi Conservative hand therapy treatments in rheumatoid arthritis--a randomized controlled trial
    A V O'Brien
    School of Health and Rehabilitation, Keele University, Keele, Staffordshire ST5 5BG, UK
    Rheumatology (Oxford) 45:577-83. 2006
    ..To evaluate the effectiveness of three different physiotherapeutic approaches in the management of the rheumatoid hand...
  63. ncbi The influence of Tai Chi training on the center of pressure trajectory during gait initiation in older adults
    Chris J Hass
    Department of Neurology, Emory University School of Medicine, Atlanta, GA 30332, USA
    Arch Phys Med Rehabil 85:1593-8. 2004
    ..To determine if a program of intense Tai Chi exercise that has been shown to reduce the risk of falling in older adults improves postural control by altering the center of pressure (COP) trajectory during gait initiation...
  64. ncbi Quantitative EEG power and asymmetry increase 36 h before a migraine attack
    Mh Bjørk
    Department of Neuroscience, Norwegian University of Science and Technology, St Olav University Hospital, Trondeim, Norway
    Cephalalgia 28:960-8. 2008
    ..Changed activity patterns in cholinergic brainstem or basal forebrain nuclei and thalamo-cortical connections before the migraine attack are hypothesized...
  65. ncbi Botulinum toxin type A (BOTOX) for the prophylactic treatment of chronic daily headache: a randomized, double-blind, placebo-controlled trial
    Ninan T Mathew
    Houston Headache Clinic, Houston, TX 77004, USA
    Headache 45:293-307. 2005
    ..The objective of this study was to evaluate the safety and efficacy of botulinum toxin type A (BoNT-A; BOTOX, Allergan, Inc.) for the prophylactic treatment of chronic daily headache (CDH)...
  66. ncbi Autologous olfactory ensheathing cell transplantation in human spinal cord injury
    F Feron
    Eskitis Institute for Cell and Molecular Therapies, Griffith University, Brisbane, QLD, Australia
    Brain 128:2951-60. 2005
    ..We conclude transplantation of autologous olfactory ensheathing cells into the injured spinal cord is feasible and is safe up to one year post-implantation...
  67. ncbi Group and home-based tai chi in elderly subjects with knee osteoarthritis: a randomized controlled trial
    Jean Michel Brismee
    Department of Rehabilitation Sciences, School of Allied Health Sciences, Texas Tech University Health Sciences Center, Texas 79430, USA
    Clin Rehabil 21:99-111. 2007
    ..To evaluate the effects of tai chi consisting of group and home-based sessions in elderly subjects with knee osteoarthritis...
  68. ncbi Sustained antihypertensive activity of telmisartan compared with valsartan
    Yves Lacourciere
    Hypertension Research Unit, Centre Hospitalier l Université de Quebec, Ste Foy, Quebec, Canada
    Blood Press Monit 9:203-10. 2004
    ..The efficacies of the long half-life telmisartan compared with shorter half-life valsartan in the last 6 h of the dosing interval following active treatment and during 24 h after a missed dose were compared...
  69. ncbi Nonresorbable copolymer implantation for gastroesophageal reflux disease: a randomized sham-controlled multicenter trial
    Jacques Deviere
    Service de Gastro entérologie et d Hépato pancréatologie, Universite Libre de Bruxelles, Hopital Erasme, Brussels, Belgium
    Gastroenterology 128:532-40. 2005
    ..This aim was to determine whether endoscopic implantation of a biocompatible nonresorbable copolymer (Enteryx; Boston Scientific Corp, Natick, MA) is a more effective therapy for gastroesophageal reflux disease (GERD) than a sham procedure...
  70. ncbi A randomized controlled trial of an enhanced balance training program to improve mobility and reduce falls in elderly patients
    Jayne Steadman
    Department of Physiotherapy, Orpington Hospital, Bromley Hospitals NHS Trust, Orpington, United Kingdom
    J Am Geriatr Soc 51:847-52. 2003
    ..To evaluate the effectiveness of an enhanced balance training program in improving mobility and well-being of elderly people with balance problems...
  71. pmc Physiotherapy for anterior knee pain: a randomised controlled trial
    D I Clark
    Department of Orthopaedics, City Hospital Nottingham, UK
    Ann Rheum Dis 59:700-4. 2000
    ..To determine the efficacy of the individual components of physiotherapy in subjects with anterior knee pain...
  72. ncbi Physician interpretations and textbook definitions of blinding terminology in randomized controlled trials
    P J Devereaux
    Department of Medicine, McMaster University, 1200 Main St W, Room 2C12, Hamilton, Ontario, Canada L8N 3Z5
    JAMA 285:2000-3. 2001
    ..The terminology authors often use to convey blinding status (single, double, and triple blinding) may be open to various interpretations...
  73. ncbi Intensity of leg and arm training after primary middle-cerebral-artery stroke: a randomised trial
    G Kwakkel
    Department of Physical Therapy and Research Institute for Fundamental and Clinical Human Movement Sciences, University Hospital Vrije Universiteit, Amsterdam, The Netherlands
    Lancet 354:191-6. 1999
    ....
  74. ncbi Unexpected haemodynamic instability associated with standard bicarbonate haemodialysis
    Luca Gabutti
    Department of Nephrology, Ospedale La Carita, Locarno, Switzerland
    Nephrol Dial Transplant 18:2369-76. 2003
    ..This study aimed to analyse haemodynamic tolerances to metabolic alkalosis during intermittent haemodialysis...
  75. pmc Does hydrotherapy improve strength and physical function in patients with osteoarthritis--a randomised controlled trial comparing a gym based and a hydrotherapy based strengthening programme
    A Foley
    Flinders University Department of Rehabilitation and Aged Care, Repatriation General Hospital, South Australia
    Ann Rheum Dis 62:1162-7. 2003
    ..To compare the effects of a hydrotherapy resistance exercise programme with a gym based resistance exercise programme on strength and function in the treatment of osteoarthritis (OA)...
  76. ncbi Forced use of the upper extremity in chronic stroke patients: results from a single-blind randomized clinical trial
    J H van der Lee
    Department of Rehabilitation Medicine, University Hospital Vrije Universiteit, and Institute for Research in Extramural Medicine, Vrije Universiteit, Amsterdam, The Netherlands
    Stroke 30:2369-75. 1999
    ..Although forced use therapy appears to improve arm function in chronic stroke patients, there is no conclusive evidence. This study evaluates the effectiveness of forced use therapy...
  77. ncbi Neuroendocrine effects of a short-term osmotic stimulus in patients with chronic schizophrenia
    W Hundt
    Department of Psychiatry and Psychotherapy, University Hospital Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
    World J Biol Psychiatry 2:27-33. 2001
    ....
  78. ncbi Blind smell: brain activation induced by an undetected air-borne chemical
    N Sobel
    Program in Neuroscience, Stanford University, CA 94305, USA
    Brain 122:209-17. 1999
    ..08). These findings localize human brain activation that was induced by an undetectable air-borne chemical (the low concentration compound)...
  79. ncbi Effect of a therapeutic intervention for the hemiplegic upper limb in the acute phase after stroke: a single-blind, randomized, controlled multicenter trial
    H M Feys
    Department of Rehabilitation Sciences, Faculty of Physical Education and Physiotherapy, University of Leuven, Belgium
    Stroke 29:785-92. 1998
    ..The purpose of this study was to investigate the effect of a specific therapeutic intervention on arm function in the acute phase after stroke...
  80. ncbi Single-blind, randomized trial of pelvic floor muscle training, biofeedback-assisted pelvic floor muscle training, and electrical stimulation in the management of overactive bladder
    Alex C Wang
    Division of Female Pelvic Medicine and Reconstructive Surgery, Department of Obstetrics Gynecology, Chang Gung University, School of Medicine, Gueishan Taoyuan, Taiwan
    Urology 63:61-6. 2004
    ..To compare the efficacy of pelvic floor muscle training (PFMT), biofeedback-assisted PFMT (BAPFMT), and electrical stimulation (ES) in the management of overactive bladder (OAB)...
  81. pmc Single blind, randomised controlled trial of pelvic floor exercises, electrical stimulation, vaginal cones, and no treatment in management of genuine stress incontinence in women
    K Bø
    Norwegian Centre for Physiotherapy Research and Norwegian University of Sport and Physical Education, PO Box 4014, Ulleval Stadion, 0806 Oslo, Norway
    BMJ 318:487-93. 1999
    ..To compare the effect of pelvic floor exercises, electrical stimulation, vaginal cones, and no treatment for genuine stress incontinence...
  82. ncbi Rimexolone 1% versus prednisolone acetate in preventing early postoperative inflammation after cataract surgery
    Sevim Kavuncu
    Ankara Ulucanlar Eye Hospital, Ankara, Turkey
    Int Ophthalmol 28:281-5. 2008
    ..To compare the efficacy and safety of rimexolone 1% and prednisolone acetate 1% ophthalmic suspensions in controlling intraocular inflammation in the early period after cataract surgery...
  83. ncbi A prospective, randomized study comparing cefepime and imipenem-cilastatin in the empirical treatment of febrile neutropenia in patients treated for haematological malignancies
    Honar Cherif
    Department of Medicine, Division of Haematology, Karolinska Hospital and Institute, Stockholm, Sweden
    Scand J Infect Dis 36:593-600. 2004
    ..Early discontinuation of antibiotic therapy in 31 patients with FUO 48 h after defervescence was not associated with an increased rate of fever relapse or mortality compared with a subgroup of 29 patients where therapy was continued...
  84. ncbi The short-term efficacy of laser, brace, and ultrasound treatment in lateral epicondylitis: a prospective, randomized, controlled trial
    Oznur Oken
    Ankara Education and Research Hospital, Department of Physical Medicine and Rehabilitation, Division of Hand Rehabilitation, Ankara, Turkey
    J Hand Ther 21:63-7; quiz 68. 2008
    ....
  85. ncbi Polyarticular corticosteroid injection versus systemic administration in treatment of rheumatoid arthritis patients: a randomized controlled study
    Rita N V Furtado
    Rheumatology Division, Universidade Federal de Sao Paulo, Sao Paulo, Brazil
    J Rheumatol 32:1691-8. 2005
    ..To study the effectiveness and side effects of polyarticular corticosteroid injection compared to systemic administration in patients with rheumatoid arthritis (RA), and to examine the differential response to injection among joints...
  86. ncbi An open-label study of alefacept plus ultraviolet B light as combination therapy for chronic plaque psoriasis
    J P Ortonne
    Department of Dermatology, hopital l Archet II, Nice, France
    J Eur Acad Dermatol Venereol 19:556-63. 2005
    ..Because alefacept and UVB target T cells in different ways, combination therapy with these two agents may lead to greater efficacy...
  87. ncbi Comparison of topical prednisolone acetate, ketorolac tromethamine and fluorometholone acetate in reducing inflammation after phacoemulsification
    Adisak Trinavarat
    Department of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand
    J Med Assoc Thai 86:143-50. 2003
    ..To compare the efficacy and ocular adverse effects of topical prednisolone acetate, ketorolac tromethamine, and fluorometholone acetate in reducing inflammation after phacoemulsification...
  88. ncbi Echocardiographic quantification of left ventricular asynchrony predicts an acute hemodynamic benefit of cardiac resynchronization therapy
    Ole A Breithardt
    Department of Cardiology, University Hospital, Aachen, Germany
    J Am Coll Cardiol 40:536-45. 2002
    ..We sought to determine whether radial left ventricular (LV) asynchrony in patients with heart failure predicts systolic function improvement with cardiac resynchronization therapy (CRT)...
  89. ncbi Efficacy of rivastigmine on activities of daily living in Sri Lankan patients with Alzheimer disease and on improving caregiver burden: a prospective study
    H A de Silva
    Department of Pharmacology, Faculty of Medicine, University of Kelaniya
    Ceylon Med J 50:106-9. 2005
    ....
  90. ncbi Evaluation of efficacy and tolerability of dothiepin hydrochloride in the management of major depression in patients suffering from rheumatoid arthritis
    H S Dhavale
    TNMC and BYL Nair Charitable Hospital, Dr AL Nair Road, Mumbai 400008
    J Indian Med Assoc 103:291-4. 2005
    ..Dothiepin hydrochloride was found to be an effective and well-tolerated drug in the management of MDD and anxiety in patients suffering from rheumatoid arthritis...
  91. ncbi Continuous low-level heat wrap therapy provides more efficacy than Ibuprofen and acetaminophen for acute low back pain
    Scott F Nadler
    Department of Physical Medicine and Rehabilitation, UMDNJ NJ Medical School, the Research Testing Laboratories, Newark, NJ 07103, USA
    Spine (Phila Pa 1976) 27:1012-7. 2002
    ..A prospective, randomized, single (investigator) blind, comparative efficacy trial was conducted...
  92. ncbi Clinical use and tolerability of voriconazole in the treatment of fungal infections in critically ill patients
    F Alvarez-Lerma
    Servicio de Medicina Intensiva, Hospital Universitari del Mar, Barcelona, Spain
    J Chemother 17:417-27. 2005
    ..In conclusion, in critically ill patients admitted to the ICU, the use of voriconazole was affective in 50% of cases. The drug was well tolerated and discontinuation of voriconazole treatment due to adverse events was not necessary...
  93. ncbi Long-term results of amitriptyline treatment for interstitial cystitis
    Arndt van Ophoven
    Department of Urology, Universitatsklinikum Munster, University of Munster, Munster, Germany
    J Urol 174:1837-40. 2005
    ..We performed a prospective, open label study to examine the safety and efficacy of the long-term administration of the tricyclic antidepressant amitriptyline in patients with interstitial cystitis (IC)...
  94. ncbi Gabapentin for the symptomatic treatment of chronic neuropathic pain in patients with late-stage lyme borreliosis: a pilot study
    S Weissenbacher
    Department of Dermatology and Allergy Biederstein, Technical University of Munich, Munich, Germany
    Dermatology 211:123-7. 2005
    ..Chronic neuropathic pain occurs in 10-15% of patients with neuroborreliosis and is difficult to treat...
  95. ncbi Acute electromechanical effects of atrioventricular coupled pacing in patients with heart failure
    Ronald Freudenberger
    Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA
    J Card Fail 14:35-40. 2008
    ..Postextrasystolic potentiation (PESP) is a property of cardiac tissue whereby two closely timed depolarizations cause the subsequent contraction to be of increased magnitude...
  96. ncbi A prospective blinded evaluation of deep brain stimulation for the treatment of secondary dystonia and primary torticollis syndromes
    Theresa E Pretto
    Department of Neurology, The University of Chicago, Illinois 60637, USA
    J Neurosurg 109:405-9. 2008
    ....
  97. ncbi Plaque removal efficacy of an advanced rotation-oscillation power toothbrush versus a new sonic toothbrush
    Aaron R Biesbrock
    Procter and Gamble Company, Mason, OH 45040 9462, USA
    Am J Dent 21:185-8. 2008
    ..To evaluate the plaque removal efficacy and safety of an advanced rotation-oscillation power toothbrush relative to a newly-introduced sonic toothbrush...
  98. ncbi Fibreoptic endoscopic evaluation of swallowing and videofluoroscopy: does examination type influence perception of pharyngeal residue severity?
    A M Kelly
    Head and Neck Tumour Centre, University College Hospital, London, UK
    Clin Otolaryngol 31:425-32. 2006
    ..The aim of the study was to investigate whether the type of instrumental swallowing examination (Fibreoptic Endoscopic Evaluation of Swallowing (FEES) or videofluoroscopy) influences perception of post-swallow pharyngeal residue...
  99. ncbi Acupuncture and moxibustion in the treatment of ulcerative colitis: a randomized controlled study
    Stefanie Joos
    Department of Medicine I, Friedrich Alexander University of Erlangen Nuremberg, Germany
    Scand J Gastroenterol 41:1056-63. 2006
    ..The objective of this study was to investigate the efficacy of acupuncture and moxibustion in the treatment of active ulcerative colitis (UC)...
  100. ncbi Severe sequence-specific toxicity when capecitabine is given after Fluorouracil and leucovorin
    Ivo M Hennig
    Cancer Research UK Centre, St James s Institute of Oncology, St James s University Hospital, Leeds LS9 7TF, United Kingdom
    J Clin Oncol 26:3411-7. 2008
    ..These treatments have similar efficacy but differ in convenience and toxicity. We therefore wished to compare their overall acceptability to patients...
  101. ncbi Effects of a rate smoothing algorithm for prevention of ventricular arrhythmias: results of the Ventricular Arrhythmia Suppression Trial (VAST)
    Paul A Friedman
    Mayo Clinic, Rochester, Minnesota 55902, USA
    Heart Rhythm 3:573-80. 2006
    ..Its efficacy in general ventricular arrhythmia prevention has not been determined...

Research Grants77

  1. Detection of Oxidized LDL in Plasma
    KENNETH DOMBROWSKI; Fiscal Year: 2009
    ....
  2. STUDY OF A FABRIC DEVICE TO EASE PATIENT MOVEMENT
    Mary Smith; Fiscal Year: 2001
    ..Three research methodologies will be employed: Double-Blind Randomized Method, Single Blind Method, and Direct Observation...
  3. Mental Practice Dosing and Mechanisms in Stroke
    Stephen Page; Fiscal Year: 2006
    ..Identification of MP mechanisms of action and optimal dosing is fundamental to cost-effective, appropriate implementation of this promising, CAM, mind-body technique, and will enable a subsequent MP clinical trial. ..
  4. Guided Pocket Recolonization (GPR) in Periodontitis
    Marc Quirynen; Fiscal Year: 2004
    ..Clinical data will be collected after 2, 4, 6, 8 and 12 weeks. The results should indicate the possible role for commensal organisms in periodontal disease and subgingival biofilm formation. ..
  5. PARAFUNCTIONAL ACTIVITY AND TEMPOROMANDIBULAR DISORDERS
    Alan Glaros; Fiscal Year: 2002
    ....
  6. Mechanisms of Acupuncture Analgesia
    Richard Harris; Fiscal Year: 2006
    ..There is a strong institutional commitment to see the applicant succeed in this task due to a tremendous need for well-trained clinical investigators in alternative and complementary medicine. ..
  7. Enhancing the Placebo Effect in Irritable Bowel Syndrome
    Ted Kaptchuk; Fiscal Year: 2006
    ..unreadable] [unreadable]..
  8. SHAM DEVICE, PILL PLACEBO OR TREATMENT FOR ARM PAIN
    Ted Kaptchuk; Fiscal Year: 2003
    ..Outcomes in these studies will include assessments of the nature and severity of upper extremity pain, function, grip and pinch strength, and mood. ..
  9. Treatment of Depression Following Bypass Surgery
    BRUCE ROLLMAN; Fiscal Year: 2007
    ..This study will enhance our understanding of the impact and course of post-CABG depression. [unreadable] [unreadable]..
  10. Divalproex and Placebo, Lithium, or Quetiapine for Mania
    Trisha Suppes; Fiscal Year: 2008
    ..abstract_text> ..
  11. Risks for Opioid Use and Abuse in Contrasting Chronic Pain Populations
    Mark Sullivan; Fiscal Year: 2009
    ....
  12. Beaumont Interstitial Cystitis Clinical Research Network
    Kenneth Peters; Fiscal Year: 2007
    ..Adverse events and complications will be monitored. Ancillary studies as agreed upon by the ICCRN will be carried out in conjunction with the clinical trial. ..
  13. Acute Treatment of Bipolar II Depression
    PATRICIA SUPPES; Fiscal Year: 2005
    ..This pilot study will provide data addressing the aims and sample size needed for a full-scale intervention trial. ..
  14. An Integrative Healing Model in IBS
    Ted Kaptchuk; Fiscal Year: 2005
    ..abstract_text> ..
  15. Intensive Dietary Restriction with Exercise in Arthritis
    Stephen P Messier; Fiscal Year: 2010
    ..This study could make intensive weight loss the standard-of- care for overweight and obese adults with knee OA, as it enhances our understanding of the OA disease process and weight-loss recommendations for older people generally. ..
  16. IMPROVING QUALITY OF PRIMARY CARE FOR ANXIETY DISORDERS
    BRUCE ROLLMAN; Fiscal Year: 2008
    ..Furthermore, it addresses alcohol use disorders - an important public health problem never addressed before in any effectiveness study for an anxiety or a mood disorder in a primary care setting. [unreadable] [unreadable]..
  17. fMRI Predictor Model for Stroke Locomotor Rehabilitation
    Bruce Dobkin; Fiscal Year: 2008
    ..The study is a step toward using fMRI as a tool to develop theory- and evidencebased practices that lessen disabilities after stroke. [unreadable] [unreadable] [unreadable]..
  18. EFFECTS OF MOVEMENT CONTEXT ON HEMIPARETIC GRASPING EARLY AFTER STROKE
    Catherine E Lang; Fiscal Year: 2010
    ..More successful performance during rehabilitation may also lead to more practice and use outside of rehabilitation. ..
  19. A Women's-Only Phase II Cardiac Rehabilitation Program
    THERESA BECKIE; Fiscal Year: 2007
    ..The findings have the potential to influence a paradigm shift for clinical practice and lead to important policy changes. ..
  20. Enhancement of informed consent in dental clinical trial
    J Goodson; Fiscal Year: 2003
    ..abstract_text> ..
  21. ADJUNCTIVE ACUPUNCTURE TO TREAT BIPOLAR DEPRESSION
    PATRICIA SUPPES; Fiscal Year: 2002
    ..Should acupuncture demonstrate efficacy in the treatment of bipolar disorder, further studies will be proposed to evaluate its utility for maintenance and prevention. ..
  22. CONTACT LENSES AND MYOPIA (CLAMP) STUDY
    JEFFREY WALLINE; Fiscal Year: 2003
    ..The CLAMP Study is the ideal scope and size of study to train Dr. Walline to become an independent investigator and has the potential to change the standard of care for young children who become nearsighted. ..
  23. Control of Finger Movements after Stroke
    CATHERINE LANG; Fiscal Year: 2003
    ..Results from these experiments may assist rehabilitation professionals in designing and implementing rehabilitation strategies to improve hand function in people after stroke. ..
  24. EXTREMITY CONSTRAINT INDUCED THERAPY EVALUATION (EXCITE)
    Steven Wolf; Fiscal Year: 2004
    ..Primary outcome measures are a laboratory motor function test and amount of extremity use in the real world setting. Changes in psychosocial functioning will also be measured. ..
  25. Latino Eye Health: A Communication Strategy for Diabetes
    Sheila West; Fiscal Year: 2007
    ..Improvements in eye care seeking behaviors should help in avoiding visual loss from diabetic retinopathy and macula edema, the leading causes of visual loss in the working age Latino population. [unreadable] [unreadable]..
  26. Alcohol Use Reduction in Methadone Individuals with HCV
    Adeline Nyamathi; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable]..
  27. Memantine Naltrexone Treatment for Opioid Dependence
    Adam Bisaga; Fiscal Year: 2009
    ..The primary aim is to test the efficacy of memantine in reducing early attrition and improving outcome in opioid-dependent individuals maintained on naltrexone. ..
  28. A PRESCRIPTION FOR ENHANCING RESIDENT QUALITY OF LIFE
    Ann Kolanowski; Fiscal Year: 2008
    ..This study holds promise for improving quality of life for nursing home residents with dementia by using theoretically based activities to respond to their needs. ..
  29. Stepped Care for Depression and Musculoskeletal Pain
    Kurt Kroenke; Fiscal Year: 2007
    ..Longitudinal assessment of the nondepressed cohort will establish the frequency and risk factors for incident depression. ..
  30. BRAIN ERPS AND COGNITIVE DEMAND IN SCHIZOPHRENIA
    Gerard Bruder; Fiscal Year: 2002
    ..A more long range clinical goal is to contribute toward the development of tests that could predict response to treatment with conventional or atypical neuroleptic medications for schizophrenia. ..
  31. The epidemiology of stress and the metabolic syndrome
    Marco Pahor; Fiscal Year: 2006
    ..abstract_text> ..
  32. Geriatric Depression: Getting Better, Getting Well
    Charles Reynolds; Fiscal Year: 2008
    ..This is an amended (A2) competing continuation of (MH37869-21). ..
  33. Promoting Self-Care with Telehomecare: Impact on Outcome
    Kathryn Bowles; Fiscal Year: 2008
    ..Findings will help guide optimal use of telehomecare in promoting self-care in the growing population of chronically ill elders whose conditions are characterized by high morbidity, complex therapies and poor quality and cost outcomes. ..
  34. Cognitive Enhancer May Facilitate Behavioral Exposure
    Barbara O Rothbaum; Fiscal Year: 2010
    ..abstract_text> ..
  35. Identification of Uncultivated and Unrecognized Pathogens of Periodontitis
    ANNE DENISE HAFFAJEE; Fiscal Year: 2010
    ..The identification of such pathogens should, over time, lead to better diagnosis of disease, optimal treatment strategies for the individual patient, new therapeutic approaches and carefully targeted approaches to prevention. ..
  36. DISCRIMINATIVE STIMULUS EFFECTS OF NICOTINE
    Kenneth Perkins; Fiscal Year: 2001
    ....
  37. CIND: Risk Factors for Conversion to Dementia
    Frederick W Unverzagt; Fiscal Year: 2010
    ....
  38. Machine Learning for Improved Mammography Screening
    Elizabeth S Burnside; Fiscal Year: 2010
    ....
  39. Naturally occurring T regulatory cells control airway hyperresponsiveness
    Erwin Gelfand; Fiscal Year: 2008
    ..abstract_text> ..
  40. Depression/Metabolic Syndrome in Mexican-American Women.
    Ma Li Wong; Fiscal Year: 2006
    ..This work will address this important area by the study of an population group who is markedly under represented in patient-oriented investigation. [unreadable] [unreadable]..
  41. ETIOLOGY OF BULIMIC PATHOLOGY--MULTIMETHOD INVESTIGATION
    Eric Stice; Fiscal Year: 2002
    ..Agras' and Taylor's labs, (2) learn state-of- the-art treatments for eating pathology and other adolescent psychopathology, (3) take courses in quantitative techniques, methodology, and ethics, and (4) receive training in grant writing. ..
  42. A home-based behavioral treatment for cigarette smoking
    Jesse Dallery; Fiscal Year: 2009
    ..As such, it may hold significant promise as a way to reduce the high rates of morbidity and mortality associated with smoking. ..
  43. Management of Mucositis with GM-CSF
    Marylin Dodd; Fiscal Year: 2008
    ..abstract not provided ..
  44. Oxidative damage, disability and mortality in elders
    Marco Pahor; Fiscal Year: 2009
    ....
  45. Sex Steroids & Mammographic Density in the Postmenopause
    Gail Greendale; Fiscal Year: 2007
    ..We will quantify the relations between the hormone and genetic exposures measured in this project and mammographic density (at baseline as well as change in density between baseline and 12 months). ..
  46. TREATMENT OF EARLY ONSET SCHIZOPHRENIA SPECTRUM (TEOSS)
    Robert Findling; Fiscal Year: 2005
    ..This study will provide information about the comparative effectiveness of the most commonly used and representative antipsychotic drugs in youth with schizophrenia spectrum disorders. ..
  47. Pathways to Psychiatric & Medical Comorbidity in Adults
    Yoko Nomura; Fiscal Year: 2005
    ..The findings of this project will provide important information for both clinicians and policy makers in order to plan more cost-effective and time-effective early intervention. ..
  48. Asian Men's Health Study
    Kyung Hee Choi; Fiscal Year: 2005
    ..abstract_text> ..
  49. Predicting Caries Risk in Underserved Toddlers
    Margherita Fontana; Fiscal Year: 2005
    ....
  50. Strategies to Reduce Hlth Inequities for America Indians
    Terri Lipman; Fiscal Year: 2005
    ..of the summit include; dissemination of the proceedings and articles in the American Journal of Nursing and Journal of Transcultural Nursing and posting on the Indian Health Services and School of Nursing web sites ..
  51. Female Condom Intervention Trial
    Kyung Hee Choi; Fiscal Year: 2005
    ..The proposed study will expand the field of HIV prevention by developing a new intervention for women. In addition, it will help broaden a range of prevention strategies for women and, in turn, help reduce their risk for HIV infection. ..
  52. Autonomic dysregulation in primary insomnia
    Gary Richardson; Fiscal Year: 2005
    ..Finally, we will use a new measure of central CRF function, the DEX-sleep latency test, to test the hypothesis that central CRF tone is higher in patients with P1. ..
  53. Predictors of Skin Cancer in Commercial Airline Pilots
    Joyce Nicholas; Fiscal Year: 2005
    ..abstract_text> ..
  54. Translational Research on Extinction and PTSD
    Barbara Rothbaum; Fiscal Year: 2005
    ..Currently, no such interventions with proven efficacy exist. ..
  55. VERY EARLY CONSTRAINT-INDUCED MOVEMENT THERAPY:STROKE
    Alexander Dromerick; Fiscal Year: 2004
    ....
  56. ENGAGEMENT OF PERSONS WITH DEMENTIA
    Jiska Cohen Mansfield; Fiscal Year: 2006
    ..In that way, it presents an exciting prospect for improving the quality of life in demented persons, thereby reducing their caregivers' burden. ..
  57. Genetic and Tissue Engineering for Aneurysms
    David Kallmes; Fiscal Year: 2004
    ..Successful implementation of this research program will advance the field of genetic and tissue engineering and will improve the care of patients harboring life-threatening cerebral aneurysms. ..
  58. PHYSIOLOGY OF ESTROGEN'S MOOD EFFECT IN MENOPAUSAL WOMEN
    Hadine Joffe; Fiscal Year: 2007
    ..Such training will lay the foundation for a career of clinical investigation into the physiology of perimenopausal depression and the impact of hot flushes on sleep, mood, and quality-of-life. ..
  59. A Lifestyle Change Program to Prevent Type 2 Diabetes
    Robin Whittemore; Fiscal Year: 2006
    ..3. To explore the reach, adoption, implementation, and maintenance of a lifestyle change program delivered by NPs in primary care settings. ..
  60. Cognitive and Spatial Systems in Action
    Laurel Buxbaum; Fiscal Year: 2006
    ..In addition, it is expected to significantly advance our understanding of lM, a common clinical disorder whose presentation, subtypes, and neuroanatomic substrate remain poorly understood. [unreadable] [unreadable]..
  61. Dronabinol naltrexone treatment for opioid dependence
    Adam Bisaga; Fiscal Year: 2010
    ..Development of an improved antagonist based approach would open it up as a viable treatment alternative for a larger population of opioid dependent individuals. ..
  62. SEX DIFFERENCES IN NICOTINE REINFORCEMENT: HUMAN/ANIMAL
    Kenneth Perkins; Fiscal Year: 2003
    ....
  63. INDIVIDUAL VARIATION IN NICOTINE SENSITIVITY IN HUMANS
    Kenneth Perkins; Fiscal Year: 2003
    ..e., in nicotine-naive individuals). Results will provide directions for future research on vulnerability to tobacco dependence and for targeted efforts to prevent smoking onset. ..
  64. HEALTH PROMOTION AND QUALITY OF LIFE IN CHRONIC ILLNESS
    Alexa Stuifbergen; Fiscal Year: 2009
    ..Longitudinal data will be analyzed with hierarchical linear models (HIM) and structural equation modeling techniques. ..
  65. Cornell ACISR for Late Life Depression
    George Alexopoulos; Fiscal Year: 2007
    ..We are confident that our work will both advance scientific knowledge and have a broad impact on the care of depressed, disabled elders. ..
  66. PREVENTION OF GERATRIC DEPRESSION
    George Alexopoulos; Fiscal Year: 2003
    ..Accordingly, we are well positioned to meet the challenges inherent in this difficult but important area of research. ..
  67. Heart Failure Adherence and Retention Trial (HART)
    Lynda Powell; Fiscal Year: 2007
    ..The questions posed by HART are as important now as they were judged to be by the study section in 2001. This request will make it possible to answer these questions conclusively. ..
  68. CHF TRIAL INVESTIGATING OUTCOMES OF EXERCISE TRAINING
    Dalane Kitzman; Fiscal Year: 2007
    ..abstract_text> ..
  69. Bone-Sparing by Ca Salts With & Without Extra Phosphorus
    Robert Heaney; Fiscal Year: 2008
    ..1 Description, ..
  70. CRC Screening in Primary Care Settings: Factors for Low Income Urban Hispanics
    Katherine DuHamel; Fiscal Year: 2008
    ..Interventions to increase CRC screening in this rapidly growing minority group could increase their rates of CRC screening and thereby decreased their mortality from CRC. [unreadable] [unreadable] [unreadable] [unreadable]..
  71. Cognitive Effects of Opioids in Older Adults
    Monique Cherrier; Fiscal Year: 2006
    ..abstract_text> ..
  72. CONTROLLED TRIAL OF SERTRALINE FOR DEPRESSION AFTER TBI
    Charles Bombardier; Fiscal Year: 2004
    ..Secondary hypotheses to be tested include whether sertraline leads to greater improvement in neuropsychological test performance, post-concussive symptoms and self-reported health status as measured by the SF 36. ..
  73. Role of non-tuberculous mycobacteria in lung disease
    Jason Stout; Fiscal Year: 2006
    ..Our findings will also assist clinicians in predicting which patients with NTM isolated from the respiratory tract will have NTM pulmonary disease. ..
  74. Culture Bias in Testing Expressive Ability In Dementia
    Ruth Tappen; Fiscal Year: 2003
    ..Both clinicians and researchers need to know which tests are appropriate, the extent to which the ethnicity of the examiner affects the results and how to interpret the scores obtained on both the newly developed and widely used tests. ..
  75. PREVENTION OF SUICIDE IN OLDER PRIMARY CARE PATIENTS
    Charles Reynolds; Fiscal Year: 2002
    ..Data will also be collected to document the impact of intervention on patient care, and on physician knowledge, attitudes, and satisfaction and test hypothesis derived from preliminary studies of the three IRCs. ..