longitudinal studies

Summary

Summary: Studies in which variables relating to an individual or group of individuals are assessed over a period of time.

Top Publications

  1. ncbi ALSPAC--the Avon Longitudinal Study of Parents and Children. I. Study methodology
    J Golding
    Institute of Child Health, University of Bristol, UK
    Paediatr Perinat Epidemiol 15:74-87. 2001
  2. ncbi Sedentary behaviors and subsequent health outcomes in adults a systematic review of longitudinal studies, 1996-2011
    Alicia A Thorp
    Baker IDI Heart and Diabetes Institute, Melbourne, Australia
    Am J Prev Med 41:207-15. 2011
  3. ncbi Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies
    Floriana S Luppino
    Department of Psychiatry, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Arch Gen Psychiatry 67:220-9. 2010
  4. ncbi Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies
    Apoor S Gami
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Am Coll Cardiol 49:403-14. 2007
  5. ncbi The spread of obesity in a large social network over 32 years
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 357:370-9. 2007
  6. ncbi Cohort Profile: the Whitehall II study
    Michael Marmot
    International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Int J Epidemiol 34:251-6. 2005
  7. ncbi Risk of dementia in diabetes mellitus: a systematic review
    Geert Jan Biessels
    Department of Neurology, Rudolf Magnus Institute of Neurosciences, University Medical Center Utrecht, Netherlands
    Lancet Neurol 5:64-74. 2006
  8. pmc Association of maternal weight gain in pregnancy with offspring obesity and metabolic and vascular traits in childhood
    Abigail Fraser
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Bristol, UK
    Circulation 121:2557-64. 2010
  9. ncbi Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies
    Esther E Freeman
    Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, UK
    AIDS 20:73-83. 2006
  10. ncbi Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory
    Randy L Buckner
    Howard Hughes Medical Institute, Washington University School of Medicine, St Louis, Missouri 63105, USA
    J Neurosci 25:7709-17. 2005

Detail Information

Publications381 found, 100 shown here

  1. ncbi ALSPAC--the Avon Longitudinal Study of Parents and Children. I. Study methodology
    J Golding
    Institute of Child Health, University of Bristol, UK
    Paediatr Perinat Epidemiol 15:74-87. 2001
    ..The study has an open policy in regard to collaboration within strict confidentiality rules...
  2. ncbi Sedentary behaviors and subsequent health outcomes in adults a systematic review of longitudinal studies, 1996-2011
    Alicia A Thorp
    Baker IDI Heart and Diabetes Institute, Melbourne, Australia
    Am J Prev Med 41:207-15. 2011
    To systematically review and provide an informative synthesis of findings from longitudinal studies published since 1996 reporting on relationships between self-reported sedentary behavior and device-based measures of sedentary time with ..
  3. ncbi Overweight, obesity, and depression: a systematic review and meta-analysis of longitudinal studies
    Floriana S Luppino
    Department of Psychiatry, Leiden University Medical Center, Albinusdreef 2, 2333 ZA Leiden, The Netherlands
    Arch Gen Psychiatry 67:220-9. 2010
    ..Association between obesity and depression has repeatedly been established. For treatment and prevention purposes, it is important to acquire more insight into their longitudinal interaction...
  4. ncbi Metabolic syndrome and risk of incident cardiovascular events and death: a systematic review and meta-analysis of longitudinal studies
    Apoor S Gami
    Division of Cardiovascular Diseases, Mayo Clinic College of Medicine, Rochester, Minnesota 55905, USA
    J Am Coll Cardiol 49:403-14. 2007
    The purpose of this research was to assess the association between the metabolic syndrome (MetSyn) and cardiovascular events and mortality by meta-analyses of longitudinal studies.
  5. ncbi The spread of obesity in a large social network over 32 years
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 357:370-9. 2007
    ..The prevalence of obesity has increased substantially over the past 30 years. We performed a quantitative analysis of the nature and extent of the person-to-person spread of obesity as a possible factor contributing to the obesity epidemic...
  6. ncbi Cohort Profile: the Whitehall II study
    Michael Marmot
    International Centre for Health and Society, Department of Epidemiology and Public Health, University College London, 1 19 Torrington Place, London WC1E 6BT, UK
    Int J Epidemiol 34:251-6. 2005
  7. ncbi Risk of dementia in diabetes mellitus: a systematic review
    Geert Jan Biessels
    Department of Neurology, Rudolf Magnus Institute of Neurosciences, University Medical Center Utrecht, Netherlands
    Lancet Neurol 5:64-74. 2006
    ..Further high quality studies need to be initiated, with objective diabetes assessment, together with reliable methods to establish the contribution of vascular disease and other comorbidity to dementia...
  8. pmc Association of maternal weight gain in pregnancy with offspring obesity and metabolic and vascular traits in childhood
    Abigail Fraser
    Medical Research Council Centre for Causal Analyses in Translational Epidemiology, Department of Social Medicine, University of Bristol, Bristol, UK
    Circulation 121:2557-64. 2010
    ..We sought to examine the association of gestational weight gain (GWG) and prepregnancy weight with offspring adiposity and cardiovascular risk factors...
  9. ncbi Herpes simplex virus 2 infection increases HIV acquisition in men and women: systematic review and meta-analysis of longitudinal studies
    Esther E Freeman
    Infectious Disease Epidemiology Unit, London School of Hygiene and Tropical Medicine, UK
    AIDS 20:73-83. 2006
    ..To estimate the sex-specific effect of herpes simplex virus type 2 (HSV-2) on the acquisition of HIV infection...
  10. ncbi Molecular, structural, and functional characterization of Alzheimer's disease: evidence for a relationship between default activity, amyloid, and memory
    Randy L Buckner
    Howard Hughes Medical Institute, Washington University School of Medicine, St Louis, Missouri 63105, USA
    J Neurosci 25:7709-17. 2005
    ..These cortical regions may be part of a network with the medial temporal lobe whose disruption contributes to memory impairment...
  11. pmc Selective drop-out in longitudinal studies and non-biased prediction of behaviour disorders
    Dieter Wolke
    Department of Psychology and Health Science Research Institute, Warwick Medical School, University of Warwick, Coventry CV4 7AL, UK
    Br J Psychiatry 195:249-56. 2009
    Participant drop-out occurs in all longitudinal studies, and if systematic, may lead to selection biases and erroneous conclusions being drawn from a study.
  12. pmc The collective dynamics of smoking in a large social network
    Nicholas A Christakis
    Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA
    N Engl J Med 358:2249-58. 2008
    ..We examined the extent of the person-to-person spread of smoking behavior and the extent to which groups of widely connected people quit together...
  13. ncbi Segmented regression analysis of interrupted time series studies in medication use research
    A K Wagner
    Department of Ambulatory Care and Prevention, Harvard Medical School and Harvard Pilgrim Health Care, Boston, MA 02215, USA
    J Clin Pharm Ther 27:299-309. 2002
    ..In this paper, we show how segmented regression analysis can be used to evaluate policy and educational interventions intended to improve the quality of medication use and/or contain costs...
  14. pmc Mediation analysis
    David P MacKinnon
    Department of Psychology, Arizona State University, Tempe, Arizona 85287 1104, USA
    Annu Rev Psychol 58:593-614. 2007
    ..Statistical methods to assess mediation and modern comprehensive approaches are described. Future directions for mediation analysis are discussed...
  15. pmc Scale-up of a decentralized HIV treatment programme in rural KwaZulu-Natal, South Africa: does rapid expansion affect patient outcomes?
    Portia C Mutevedzi
    Africa Centre for Health and Population Studies, Mtubatuba, South Africa
    Bull World Health Organ 88:593-600. 2010
    ....
  16. ncbi Comparison of the minimally important difference for two health state utility measures: EQ-5D and SF-6D
    Stephen J Walters
    Health Economics and Decision Science, School of Health and Related Research, University of Sheffield, UK
    Qual Life Res 14:1523-32. 2005
    ..Empirical work is required to determine what the smallest change is in utility scores that can be regarded as important and whether this change in utility value is constant across measures and conditions...
  17. ncbi Prior juvenile diagnoses in adults with mental disorder: developmental follow-back of a prospective-longitudinal cohort
    Julia Kim-Cohen
    Institute of Psychiatry, King s College, London, England
    Arch Gen Psychiatry 60:709-17. 2003
    ..If most adults with mental disorders are found to have a juvenile psychiatric history, this would shift etiologic research and prevention policy to focus more on childhood mental disorders...
  18. ncbi Potential endpoints for clinical trials in premanifest and early Huntington's disease in the TRACK-HD study: analysis of 24 month observational data
    Sarah J Tabrizi
    UCL Institute of Neurology, University College London, Queen Square, London, UK
    Lancet Neurol 11:42-53. 2012
    ..TRACK-HD is a prospective observational biomarker study in premanifest and early Huntington's disease (HD). In this report we define a battery of potential outcome measures for therapeutic trials...
  19. ncbi Participation in cognitively stimulating activities and risk of incident Alzheimer disease
    Robert S Wilson
    Rush Alzheimer s Disease Center, 1645 W Jackson Blvd, Suite 675, Chicago, IL 60612, USA
    JAMA 287:742-8. 2002
    ..Frequent participation in cognitively stimulating activities has been hypothesized to reduce risk of Alzheimer disease (AD), but prospective data regarding an association are lacking...
  20. ncbi Mixed brain pathologies account for most dementia cases in community-dwelling older persons
    Julie A Schneider
    Rush Alzheimer s Disease Center, Rush University Medical Center, Armour Academic Center, 600 S Paulina Street, Suite 1022F, Chicago, IL 60612, USA
    Neurology 69:2197-204. 2007
    ..To examine the spectrum of neuropathology in persons from the Rush Memory and Aging Project, a longitudinal community-based clinical-pathologic cohort study...
  21. pmc Midlife vascular risk factors and Alzheimer's disease in later life: longitudinal, population based study
    M Kivipelto
    Department of Neuroscience and Neurology, University of Kuopio, PO Box 1627, 70211 Kuopio, Finland
    BMJ 322:1447-51. 2001
    ..To examine the relation of midlife raised blood pressure and serum cholesterol concentrations to Alzheimer's disease in later life...
  22. ncbi When is baseline adjustment useful in analyses of change? An example with education and cognitive change
    M Maria Glymour
    Department of Society, Human Development, and Health, Harvard School of Public Health, Boston, MA 02215, USA
    Am J Epidemiol 162:267-78. 2005
    ..In some cases, change-score analyses without baseline adjustment provide unbiased causal effect estimates when baseline-adjusted estimates are biased...
  23. ncbi Maternal seafood consumption in pregnancy and neurodevelopmental outcomes in childhood (ALSPAC study): an observational cohort study
    Joseph R Hibbeln
    Laboratory of Membrane Biophysics and Biochemistry, US National Institute on Alcohol Abuse and Alcoholism, US National Institutes of Health, Bethesda, MD 20952, USA
    Lancet 369:578-85. 2007
    ..We used the Avon Longitudinal Study of Parents and Children (ALSPAC) to assess the possible benefits and hazards to a child's development of different levels of maternal seafood intake during pregnancy...
  24. ncbi Size at birth and early childhood growth in relation to maternal smoking, parity and infant breast-feeding: longitudinal birth cohort study and analysis
    Ken K L Ong
    Department of Paediatrics, University of Cambridge, Addenbrookes Hospital, Cambridge, UK
    Pediatr Res 52:863-7. 2002
    ..The sequence of fetal growth restraint and postnatal catch-up growth may predispose to obesity risk in this contemporary population...
  25. ncbi Development of depression from preadolescence to young adulthood: emerging gender differences in a 10-year longitudinal study
    B L Hankin
    Department of Psychology, University of Wisconsin, Madison 53706, USA
    J Abnorm Psychol 107:128-40. 1998
    ....
  26. ncbi Increased telomerase activity and comprehensive lifestyle changes: a pilot study
    Dean Ornish
    Department of Medicine, University of California, San Francisco, CA, USA
    Lancet Oncol 9:1048-57. 2008
    ..We aimed to assess whether 3 months of intensive lifestyle changes increased telomerase activity in peripheral blood mononuclear cells (PBMC)...
  27. ncbi Midlife hand grip strength as a predictor of old age disability
    T Rantanen
    Epidemiology, Demography and Biometry Program, National Institute on Aging, National Institutes of Health, Bethesda, MD, USA
    JAMA 281:558-60. 1999
    ..Poor muscle strength, functional limitations, and disability often coexist, but whether muscle strength during midlife predicts old age functional ability is not known...
  28. pmc A systematic review of longitudinal studies on the association between depression and smoking in adolescents
    Michael O Chaiton
    Dalla Lana School of Public Health, University of Toronto, Toronto, Canada
    BMC Public Health 9:356. 2009
    ..It is well-established that smoking and depression are associated in adolescents, but the temporal ordering of the association is subject to debate...
  29. ncbi Maternal antenatal anxiety and children's behavioural/emotional problems at 4 years. Report from the Avon Longitudinal Study of Parents and Children
    Thomas G O'Connor
    Institute of Psychiatry, Denmark Hill, London
    Br J Psychiatry 180:502-8. 2002
    ..Animal experiments suggest that maternal stress and anxiety during pregnancy have long-term effects on the behaviour of the offspring...
  30. pmc Examining a bidirectional association between depressive symptoms and diabetes
    Sherita Hill Golden
    Johns Hopkins University School of Medicine, Department of Medicine, Baltimore, MD 21205, USA
    JAMA 299:2751-9. 2008
    ..Depressive symptoms are associated with development of type 2 diabetes, but it is unclear whether type 2 diabetes is a risk factor for elevated depressive symptoms...
  31. ncbi Diabetes as a risk factor for dementia and mild cognitive impairment: a meta-analysis of longitudinal studies
    G Cheng
    Department of Nuclear Medicine and Endocrinology, The First Affiliated Hospital, Chongqing Medical University, Chongqing, China
    Intern Med J 42:484-91. 2012
    ..VD) and any dementia) and mild cognitive impairment (MCI) by using a quantitative meta-analysis of longitudinal studies. EMBASE and MEDLINE were searched for articles published up to December 2010...
  32. ncbi Longitudinal study of physical activity and sedentary behavior in children
    Laura Basterfield
    Institute of Health and Society, Human Nutrition Research Centre, Newcastle University, M1 151 Leech Building Medical School, Framlington Place, Newcastle upon Tyne NE2 4HH, United Kingdom
    Pediatrics 127:e24-30. 2011
    ....
  33. ncbi Time spent being sedentary and weight gain in healthy adults: reverse or bidirectional causality?
    Ulf Ekelund
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Cambridge, United Kingdom
    Am J Clin Nutr 88:612-7. 2008
    ..Whether obesity is a cause or a consequence of a sedentary lifestyle has not yet been fully elucidated, which leaves uncertainty about the direction of causality...
  34. ncbi Cohort Profile: the Australian Longitudinal Study on Women's Health
    Christina Lee
    School of Psychology, University of Queensland, St Lucia, QLD, Australia
    Int J Epidemiol 34:987-91. 2005
  35. pmc What are the causal effects of breastfeeding on IQ, obesity and blood pressure? Evidence from comparing high-income with middle-income cohorts
    Marie Jo A Brion
    MRC Centre for Causal Analyses in Translational Epidemiology, University of Bristol, Bristol, UK
    Int J Epidemiol 40:670-80. 2011
    ..This is applied to assessing causal effects of breastfeeding on child blood pressure (BP), body mass index (BMI) and intelligence quotient (IQ)...
  36. pmc Telomere length trajectory and its determinants in persons with coronary artery disease: longitudinal findings from the heart and soul study
    Ramin Farzaneh-Far
    Division of Cardiology, San Francisco General Hospital, San Francisco, California, USA
    PLoS ONE 5:e8612. 2010
    ..We sought to investigate the longitudinal trajectory of telomere length, and to identify the independent predictors of telomere shortening, in persons with coronary artery disease...
  37. ncbi The age-dependent relation of blood pressure to cognitive function and dementia
    Chengxuan Qiu
    Aging Research Centre, Division of Geriatric Epidemiology and Medicine, Department of Neurotec, Karolinska Institute and Stockholm Gerontology Research Centre, Stockholm, Sweden
    Lancet Neurol 4:487-99. 2005
    ..inverse association between blood pressure and the prevalence of dementia and Alzheimer's disease, whereas longitudinal studies yield mixed results that largely depend on the age at which blood pressure is measured and the time ..
  38. pmc Biological and clinical manifestations of Huntington's disease in the longitudinal TRACK-HD study: cross-sectional analysis of baseline data
    Sarah J Tabrizi
    UCL Institute of Neurology, University College London, Queen Square, London, UK
    Lancet Neurol 8:791-801. 2009
    ..Our aim was to identify sensitive and reliable biomarkers in premanifest carriers of mutated HTT and in individuals with early HD that could provide essential methodology for the assessment of therapeutic interventions...
  39. pmc Fetal and early life growth and body mass index from birth to early adulthood in 1958 British cohort: longitudinal study
    T J Parsons
    Department of Paediatric Epidemiology and Biostatistics, Institute of Child Health, London WC1N 1EH, UK
    BMJ 323:1331-5. 2001
    ....
  40. ncbi Risk factors for work-related musculoskeletal disorders: A systematic review of recent longitudinal studies
    Bruno R da Costa
    University of Alberta, Edmonton, Canada
    Am J Ind Med 53:285-323. 2010
    ..This systematic review was designed and conducted in an effort to evaluate the evidence currently available for the many suggested risk factors for work-related musculoskeletal disorders...
  41. ncbi The life course prospective design: an example of benefits and problems associated with study longevity
    M E J Wadsworth
    Medical Research Council National Survey of Health and Development, Department of Epidemiology and Public Health, Royal Free Hospital, University College Medical School, 1 19 Torrington Place, London WC1E 6BT, UK
    Soc Sci Med 57:2193-205. 2003
    ..That seems also likely in Britain's two later born national birth cohort studies that have continued into adulthood...
  42. ncbi Tracking of obesity and physical activity from childhood to adulthood: the Physical Activity Longitudinal Study
    Katya M Herman
    School of Kinesiology and Health Studies, Queen s University, Kingston, Ontario
    Int J Pediatr Obes 4:281-8. 2009
    ..Tracking studies have often had limited follow-up lengths. The aim was to investigate BMI and PA tracking over 22 years from youth to adulthood...
  43. ncbi Sex ratio of multiple sclerosis in Canada: a longitudinal study
    Sarah Michelle Orton
    Wellcome Trust Centre for Human Genetics and Department of Clinical Neurology, University of Oxford, Oxford, UK
    Lancet Neurol 5:932-6. 2006
    ..We reasoned that if a sex-specific change in incidence was occurring, the female to male sex ratio would serve as a surrogate of incidence change...
  44. ncbi Sleep duration from infancy to adolescence: reference values and generational trends
    Ivo Iglowstein
    Growth and Development Center, University Children s Hospital, Zurich, Switzerland
    Pediatrics 111:302-7. 2003
    ....
  45. ncbi Overweight, obesity, and health-related quality of life among adolescents: the National Longitudinal Study of Adolescent Health
    Karen C Swallen
    Demography and Ecology, University of Wisconsin, Madison, Wisconsin 53705, USA
    Pediatrics 115:340-7. 2005
    ..We investigated the association between obesity and health-related quality of life in a nationally representative sample of adolescents...
  46. pmc A prospective study of the emergence of early behavioral signs of autism
    Sally Ozonoff
    MIND Institute, University of California Davis, Sacramento, California 95817, USA
    J Am Acad Child Adolesc Psychiatry 49:256-66.e1-2. 2010
    ..To examine prospectively the emergence of behavioral signs of autism in the first years of life in infants at low and high risk for autism...
  47. ncbi Mortality risk associated with low-trauma osteoporotic fracture and subsequent fracture in men and women
    Dana Bliuc
    Garvan Institute of Medical Research, 384 Victoria St, Sydney, NSW 2010, Australia
    JAMA 301:513-21. 2009
    ..There are few data on long-term mortality following osteoporotic fracture and fewer following subsequent fracture...
  48. pmc Type 2 diabetes mellitus as a risk factor for the onset of depression: a systematic review and meta-analysis
    A Nouwen
    School of Psychology, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Diabetologia 53:2480-6. 2010
    ..This study examined the association of diabetes and the onset of depression by reviewing the literature and conducting a meta-analysis of longitudinal studies on this topic.
  49. ncbi The RAND-36 measure of health-related quality of life
    R D Hays
    UCLA Department of Medicine, UCLA School of Medicine, 90095 1736, USA
    Ann Med 33:350-7. 2001
    ..The paper also discusses the availability of the RAND-36 in multiple languages and summarizes changes that are incorporated in the latest version of the survey...
  50. pmc Longitudinal versus cross-sectional evaluations of leukocyte telomere length dynamics: age-dependent telomere shortening is the rule
    W Chen
    Tulane Center for Cardiovascular Health, Tulane University Health Sciences Center, New Orleans, Louisiana, USA
    J Gerontol A Biol Sci Med Sci 66:312-9. 2011
    Leukocyte telomere length (LTL) is considered a biomarker of human aging and based on cross-sectional studies it shortens with age. However, longitudinal studies reported that many adults display LTL lengthening.
  51. pmc Cohort study of depressed mood during pregnancy and after childbirth
    J Evans
    Division of Psychiatry, University of Bristol, Bristol BS2 8DZ
    BMJ 323:257-60. 2001
    ..To follow mothers' mood through pregnancy and after childbirth and compare reported symptoms of depression at each stage...
  52. ncbi Association of the Mediterranean dietary pattern with the incidence of depression: the Seguimiento Universidad de Navarra/University of Navarra follow-up (SUN) cohort
    Almudena Sanchez-Villegas
    Department of Clinical Sciences, University of Las Palmas de Gran Canaria, Spain
    Arch Gen Psychiatry 66:1090-8. 2009
    ..Adherence to the Mediterranean dietary pattern (MDP) is thought to reduce inflammatory, vascular, and metabolic processes that may be involved in the risk of clinical depression...
  53. ncbi Longitudinal assessment of mental health problems among active and reserve component soldiers returning from the Iraq war
    Charles S Milliken
    Division of Psychiatry and Neuroscience, Walter Reed Army Institute of Research, US Army Medical Research and Materiel Command, Silver Spring, Maryland 20910, USA
    JAMA 298:2141-8. 2007
    ..A previous article focusing only on the initial screening is likely to have underestimated the mental health burden...
  54. ncbi Longitudinal magnetic resonance imaging studies of older adults: a shrinking brain
    Susan M Resnick
    Laboratory of Personality and Cognition, National Institute on Aging, Baltimore, Maryland 21224 6825, USA
    J Neurosci 23:3295-301. 2003
    ..from cross-sectional neuroimaging studies, but direct measurements of gray and white matter changes from longitudinal studies are lacking...
  55. ncbi Moderate-to-vigorous physical activity from ages 9 to 15 years
    Philip R Nader
    Department of Pediatrics, University of California San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0927, USA
    JAMA 300:295-305. 2008
    ..Although at least 60 minutes per day of moderate-to-vigorous physical activity (MVPA) is recommended, few longitudinal studies have determined the recent patterns of physical activity of youth.
  56. ncbi Imaging cerebral atrophy: normal ageing to Alzheimer's disease
    Nick C Fox
    Dementia Research Group, Institute of Neurology, Queen Square, London WC1N 3BG, UK
    Lancet 363:392-4. 2004
    ..Such use of MRI requires accurate understanding of how brain changes in normal ageing differ from those in dementia...
  57. pmc Effect of bednets and indoor residual spraying on spatio-temporal clustering of malaria in a village in south Ethiopia: a longitudinal study
    Eskindir Loha
    School of Public and Environmental Health, Hawassa University, Hawassa, Ethiopia
    PLoS ONE 7:e47354. 2012
    ..The objective of this study was to assess the effect of mass distribution of bednets and indoor residual spraying (IRS) with insecticides on the spatio-temporal clustering of malaria in one malaria endemic village in south Ethiopia...
  58. pmc Persistent arthralgia induced by Chikungunya virus infection is associated with interleukin-6 and granulocyte macrophage colony-stimulating factor
    Angela Chow
    Communicable Disease Centre, Singapore
    J Infect Dis 203:149-57. 2011
    ..Chikungunya virus (CHIKV) infection induces arthralgia. The involvement of inflammatory cytokines and chemokines has been suggested, but very little is known about their secretion profile in CHIKV-infected patients...
  59. pmc Clustering of serotypes in a longitudinal study of Streptococcus pneumoniae carriage in three day care centres
    Tuija Leino
    National Public Health Institute KTL, Mannerheimintie 166, FIN 00300 Helsinki, Finland
    BMC Infect Dis 8:173. 2008
    ..Here we report the first longitudinal study of pneumococcal carriage that records serotype specific exposure to pneumococci simultaneously within the two most important mixing groups, families and day care facilities...
  60. pmc Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease
    Madhav Thambisetty
    King s College London, Institute of Psychiatry, De Crespigny Park, London SE5 8AF, England
    Arch Gen Psychiatry 67:739-48. 2010
    ..Blood-based analytes may be indicators of pathological processes in Alzheimer disease (AD)...
  61. pmc Socioeconomic position and health status of people who live near busy roads: the Rome Longitudinal Study (RoLS)
    Giulia Cesaroni
    Department of Epidemiology of the Regional Health Service, Lazio Region, Via S, Costanza 53, 00198 Rome, Italy
    Environ Health 9:41. 2010
    ..The issue has large public health consequences but few studies have described the main socio-demographic characteristics of people exposed to traffic...
  62. ncbi Mortality, CD4 cell count decline, and depressive symptoms among HIV-seropositive women: longitudinal analysis from the HIV Epidemiology Research Study
    J R Ickovics
    Yale University, Department of Epidemiology and Public Health, PO Box 208034, 60 College St, Suite 415, New Haven, CT 06520 8034, USA
    JAMA 285:1466-74. 2001
    ..The impact of depression on morbidity and mortality among women with human immunodeficiency virus (HIV) has not been examined despite the fact that women with HIV have substantially higher rates of depression than their male counterparts...
  63. pmc Plasmodium falciparum genetic diversity maintained and amplified over 5 years of a low transmission endemic in the Peruvian Amazon
    OraLee H Branch
    Department of Medical Parasitology, New York University, USA
    Mol Biol Evol 28:1973-86. 2011
    ..The population structure, genetic diversity, appearance/disappearance of the different haplotypes from 2003 to 2007 provides a genome-wide "real-time" perspective of P. falciparum parasites in a low transmission region...
  64. ncbi Physical activity change during adolescence: a systematic review and a pooled analysis
    Samuel C Dumith
    Post Graduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil
    Int J Epidemiol 40:685-98. 2011
    ..Therefore, the purpose was to systematically review the international literature regarding PA change during adolescence, and to quantify that change according to a series of study variables, exploring gender-and-age differences...
  65. pmc Associations of gestational weight gain with maternal body mass index, waist circumference, and blood pressure measured 16 y after pregnancy: the Avon Longitudinal Study of Parents and Children (ALSPAC)
    Abigail Fraser
    MRC Centre for Causal Analyses in Translational Epidemiology and the School of Social and Community Medicine, University of Bristol, Bristol, United Kingdom
    Am J Clin Nutr 93:1285-92. 2011
    ..Little is known about associations of gestational weight gain (GWG) with long-term maternal health...
  66. pmc Genetic markers of adult obesity risk are associated with greater early infancy weight gain and growth
    Cathy E Elks
    MRC Epidemiology Unit, Addenbrooke s Hospital, Cambridge, United Kingdom
    PLoS Med 7:e1000284. 2010
    ..Exploration of these genotype associations in children may provide insights into the timing of weight changes leading to adult obesity...
  67. pmc Decreased sexual risk behavior in the era of HAART among HIV-infected urban and rural South Africans attending primary care clinics
    Kartik K Venkatesh
    Department of Community Health, Brown University, Providence, Rhode Island, USA
    AIDS 24:2687-96. 2010
    ..In light of increasing access to HAART in sub-Saharan Africa, we conducted a longitudinal study to assess the impact of HAART on sexual risk behaviors among HIV-infected South Africans in urban and rural primary care clinics...
  68. pmc Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy
    Pietro Presicce
    Division of Molecular Immunology, Cincinnati Children s Hospital Research Foundation, Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, United States of America
    PLoS ONE 6:e28118. 2011
    ..The most striking difference in terms of functional molecules was the high expression of CD39 by Tregs in untreated patients, which HAART only partially controlled...
  69. pmc Developmental potential in the first 5 years for children in developing countries
    Sally Grantham-McGregor
    Centre for International Child Health, Institute of Child Health, University College London, UK
    Lancet 369:60-70. 2007
    ..These disadvantaged children are likely to do poorly in school and subsequently have low incomes, high fertility, and provide poor care for their children, thus contributing to the intergenerational transmission of poverty...
  70. ncbi An explanation for the apparent dissociation between clinical remission and continued structural deterioration in rheumatoid arthritis
    A K Brown
    Leeds Institute of Molecular Medicine, University of Leeds, and Chapel Allerton Hospital, Leeds, UK
    Arthritis Rheum 58:2958-67. 2008
    ..The purpose of this study was to evaluate the long-term significance of subclinical synovitis and its relationship to structural outcome...
  71. pmc Association between children's experience of socioeconomic disadvantage and adult health: a life-course study
    Richie Poulton
    Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin, New Zealand
    Lancet 360:1640-5. 2002
    ..We aimed to test the hypothesis that children's experience of socioeconomic disadvantage is associated with a wide range of health risk factors and outcomes in adult life...
  72. ncbi Association between child and adolescent television viewing and adult health: a longitudinal birth cohort study
    Robert J Hancox
    Dunedin Multidisciplinary Health and Development Research Unit, Department of Preventive and Social Medicine, Dunedin School of Medicine, University of Otago, PO Box 913, Dunedin New Zealand
    Lancet 364:257-62. 2004
    ..However, there have been no longitudinal studies of childhood viewing and adult health...
  73. ncbi Strategies for multiple imputation in longitudinal studies
    Michael Spratt
    Department of Social Medicine, Faculty of Medicine and Dentistry, University of Bristol, Canynge Hall, 39 Whatley Road, Bristol BS8 2PS, United Kingdom
    Am J Epidemiol 172:478-87. 2010
    ..When data are missing, such preliminary analyses should be routinely undertaken and reported, regardless of whether multiple imputation is used in the final analysis...
  74. ncbi Physical activity level and health-related quality of life in the general adult population: a systematic review
    Raphael Bize
    Centre for Health Promotion Studies, School of Public Health, University of Alberta, Edmonton, Canada
    Prev Med 45:401-15. 2007
    ..Little is known regarding health-related quality of life and its relation with physical activity level in the general population. Our primary objective was to systematically review data examining this relationship...
  75. pmc A longitudinal household study of Streptococcus pneumoniae nasopharyngeal carriage in a UK setting
    M Hussain
    Immunisation Department, Communicable Disease Surveillance Centre, Health Protection Agency Centre for Infections, London, UK
    Epidemiol Infect 133:891-8. 2005
    ..pneumoniae is common in a UK setting in the pre-conjugate vaccine era. PCV would protect against a large proportion of carriage isolates. However, the impact of vaccination on non-vaccine serotypes will need to be monitored...
  76. pmc The global burden of diarrhoeal disease, as estimated from studies published between 1992 and 2000
    Margaret Kosek
    Division of Geographic and International Medicine, University of Virginia, Charlottesville, VA 22908, USA
    Bull World Health Organ 81:197-204. 2003
    ..There has not been a concurrent decrease in morbidity rates attributable to diarrhoea. As population growth is focused in the poorest areas, the total morbidity component of the disease burden is greater than previously...
  77. ncbi The impact of weight change on cardiovascular disease risk factors in young black and white adults: the CARDIA study
    J E Norman
    Division of Epiemiology and Clinical Applications, National Heart, Lung and Blood Institute, Bethesda, MD 20892 7938, USA
    Int J Obes Relat Metab Disord 27:369-76. 2003
    ..To quantify the relation between weight change and change in blood pressure, lipids and insulin levels, and determine if this relation differs by race or initial level of obesity...
  78. ncbi Determinants of accelerated progression of arterial stiffness in normotensive subjects and in treated hypertensive subjects over a 6-year period
    Athanase Benetos
    Centre d Investigations Préventives et Cliniques, Paris, France
    Circulation 105:1202-7. 2002
    ..The aim of the present longitudinal study was to compare the progression of aortic stiffness over a 6-year period in treated hypertensive subjects and normotensive subjects, and to evaluate the determinants of this progression...
  79. ncbi Female and male antisocial trajectories: from childhood origins to adult outcomes
    Candice L Odgers
    Department of Psychology and Social Behavior, University of California Irvine, Irvine, CA92697 7085, USA
    Dev Psychopathol 20:673-716. 2008
    ..Implications for theory, research, and practice are discussed...
  80. ncbi Characteristics of larval anopheline (Diptera: Culicidae) habitats in Western Kenya
    J E Gimnig
    Kenya Medical Research Institute, Centre for Vector Biology and Control Research, Kisumu
    J Med Entomol 38:282-8. 2001
    ..Together, these results indicate that An. gambiae and An. arabiensis have similar requirements for the larval environment and that, at least in western Kenya, they do not segregate into separate habitats...
  81. ncbi Population structure and transmission dynamics of Plasmodium vivax in rural Amazonia
    Marcelo U Ferreira
    Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA
    J Infect Dis 195:1218-26. 2007
    ..We conclude that the small-area genetic diversity in P. vivax populations under low-level transmission is not severely constrained by the low rates of effective meiotic recombination, with clear public health implications...
  82. ncbi Human telomere biology: pitfalls of moving from the laboratory to epidemiology
    Abraham Aviv
    The Center of Human Development and Aging of New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
    Int J Epidemiol 35:1424-9. 2006
    ..Here we explain some of the reasons for this variability and propose several principles that should be considered in conducting epidemiological telomere research. Ignoring these principles could lead to misleading conclusions...
  83. ncbi Asthma Control Test: reliability, validity, and responsiveness in patients not previously followed by asthma specialists
    Michael Schatz
    Kaiser Permanente Medical Center, San Diego, CA 92111, USA
    J Allergy Clin Immunol 117:549-56. 2006
    ..The development of the Asthma Control Test (ACT), a short, simple, patient-based tool for identifying patients with poorly controlled asthma, was recently described in patients under the routine care of an asthma specialist...
  84. ncbi Risk factors for relapse following treatment for first episode psychosis: a systematic review and meta-analysis of longitudinal studies
    M Alvarez-Jimenez
    Centre for Youth Mental Health, The University of Melbourne, Australia ORYGEN Youth Health Research Centre, Australia
    Schizophr Res 139:116-28. 2012
    ..The aim of this study was to systematically compile and analyse risk factors for and rates of relapse in the early course of psychosis...
  85. ncbi Accuracy of teen and parental reports of obesity and body mass index
    E Goodman
    Division of Adolescent Young Adult Medicine, Children s Hospital, Boston, Massachusetts, USA
    Pediatrics 106:52-8. 2000
    ....
  86. ncbi Late-life engagement in social and leisure activities is associated with a decreased risk of dementia: a longitudinal study from the Kungsholmen project
    Hui Xin Wang
    Aging Research Center, Division of Geriatric Epidemiology and Medicine, Neurotec, Karolinska Institutet, and Stockholm Gerontology Research Center, Stockholm, Sweden
    Am J Epidemiol 155:1081-7. 2002
    ....
  87. ncbi Life satisfaction and suicide: a 20-year follow-up study
    H Koivumaa-Honkanen
    Department of Psychiatry, Kuopio University Hospital, Kuopio, Finland
    Am J Psychiatry 158:433-9. 2001
    ..The authors investigated whether self-reported life satisfaction predicted suicide over a period of 20 years (1976-1995) in adults unselected for mental health status...
  88. ncbi Temporal and spatial dynamics of brain structure changes during extensive learning
    Bogdan Draganski
    Department of Neurology, University of Regensburg, 93053 Regensburg, Germany
    J Neurosci 26:6314-7. 2006
    ..These results indicate that the acquisition of a great amount of highly abstract information may be related to a particular pattern of structural gray matter changes in particular brain areas...
  89. pmc Development of adiposity in adolescence: five year longitudinal study of an ethnically and socioeconomically diverse sample of young people in Britain
    Jane Wardle
    Cancer Research UK Health Behaviour Unit, Department of Epidemiology and Public Health, University College London, London WC1E 6BT
    BMJ 332:1130-5. 2006
    ..To examine the developmental trajectory of obesity in adolescence in relation to sex, ethnicity, and socioeconomic status...
  90. ncbi Rise in insulin resistance is associated with escalated telomere attrition
    Jeffrey P Gardner
    Hypertension Research Center, Cardiovascular Research Institute, University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, NJ 07103, USA
    Circulation 111:2171-7. 2005
    ..We therefore tested the hypothesis that a rise in insulin resistance in concert with gain in body mass is associated with accelerated white blood cell telomere attrition...
  91. ncbi Total and undercarboxylated osteocalcin predict changes in insulin sensitivity and β cell function in elderly men at high cardiovascular risk
    Monica Bullo
    Human Nutrition Unit, Facultat de Medicina i Ciencies de la Salut, IISPV, Universitat Rovira i Virgili, Reus, Spain
    Am J Clin Nutr 95:249-55. 2012
    ..Osteocalcin has been related to insulin secretion in experimental models. Few prospective studies have evaluated the association between circulating osteocalcin concentrations and insulin secretion and sensitivity in humans...
  92. ncbi Recurrence after recovery from major depressive disorder during 15 years of observational follow-up
    T I Mueller
    NIMH Collaborative Program on the Psychobiology of Depression Clinical Studies, Brown University School of Medicine, Providence, RI 02906, USA
    Am J Psychiatry 156:1000-6. 1999
    ....
  93. ncbi Association between regional adipose tissue distribution and both type 2 diabetes and impaired glucose tolerance in elderly men and women
    Bret H Goodpaster
    Department of Medicine, University of Pittsburgh Medical Center, Pennsylvania 15213, USA
    Diabetes Care 26:372-9. 2003
    ....
  94. pmc Telomere length and mortality: a study of leukocytes in elderly Danish twins
    Masayuki Kimura
    Center of Human Development and Aging, New Jersey Medical School, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
    Am J Epidemiol 167:799-806. 2008
    ..Leukocyte telomere dynamics might help explain the boundaries of the human life span...
  95. ncbi Longitudinal studies of cognition and functional outcome in schizophrenia: implications for MATRICS
    Michael F Green
    Department of Psychiatry and Biobehavioral Sciences, Geffen School of Medicine at UCLA, USA
    Schizophr Res 72:41-51. 2004
    ..The current paper presents a review of 18 recently published longitudinal studies (minimum 6-month follow up) of the relationships between cognition and community outcome in schizophrenia...
  96. ncbi The burden of disease associated with filaggrin mutations: a population-based, longitudinal birth cohort study
    John Henderson
    Department of Community Based Medicine, University of Bristol, Bristol, United Kingdom
    J Allergy Clin Immunol 121:872-7.e9. 2008
    ..Atopic disease is a major health problem. Mutations in the filaggrin gene (FLG) confer major susceptibility to eczema and related asthma...
  97. ncbi Sex differences in the relationship between social support and risk for major depression: a longitudinal study of opposite-sex twin pairs
    Kenneth S Kendler
    Department of Psychiatry, Medical College of Virginia, Virginia Commonwealth University, Richmond, VA 23298 0126, USA
    Am J Psychiatry 162:250-6. 2005
    ..Prior studies have suggested that women are more sensitive to the depressogenic effects of low social support, but most of these studies had substantial methodologic limitations...
  98. ncbi Incidence and risk factors for chronic elevation of alanine aminotransferase levels in HIV-infected persons without hepatitis b or c virus co-infection
    Helen Kovari
    Division of Infectious Diseases and Hospital Epidemiology, University Hospital, Zurich, Switzerland
    Clin Infect Dis 50:502-11. 2010
    ..Chronic liver disease in human immunodeficiency virus (HIV)-infected patients is mostly caused by hepatitis virus co-infection. Other reasons for chronic alanine aminotransferase (ALT) elevation are more difficult to diagnose...
  99. pmc Longitudinal studies of Plasmodium falciparum malaria in pregnant women living in a rural Cameroonian village with high perennial transmission
    Rose F G Leke
    Faculty of Medicine and Biomedical Research, The Biotechnology Center, University of Yaounde 1, Yaounde, Cameroon
    Am J Trop Med Hyg 83:996-1004. 2010
    ..009). Genotyping showed that 77% of placental parasites were acquired ≥ 30 wks in pregnancy. These results help identify the extent of malaria-associated changes women experience during pregnancy...
  100. pmc Longitudinal patterns and predictors of alcohol consumption in the United States
    Alison A Moore
    David Geffen School of Medicine at UCLA, Division of Geriatrics, 10945 Le Conte Ave, Suite 2339, Los Angeles, CA 90095 1687, USA
    Am J Public Health 95:458-65. 2005
    ..We examined demographic predictors of longitudinal patterns in alcohol consumption...
  101. ncbi Longitudinal stability of sedentary behaviors and physical activity during early adolescence
    Lennart Raudsepp
    University of Tartu Institute of Sport Pedagogy and Coaching Science and Estonian Centre of Behavioral and Health Sciences, Tartu, Estonia
    Pediatr Exerc Sci 20:251-62. 2008
    ..Interventions targeted at "high-risk" groups to reduce sedentary behaviors during early adolescence are encouraged...

Research Grants74

  1. Longitudinal Studies of Primary Biliary Cirrhosis
    MARLYN MAYO; Fiscal Year: 2006
    ..In addition, the correlation between each of the putative surrogate markers will be analyzed. The results of this analysis will then be used to design future clinical trials in the field of PBC. [unreadable] [unreadable]..
  2. Bone Deficits and Excess Adiposity after Pediatric Bone Marrow Transplantation
    Sogol Mostoufi-Moab; Fiscal Year: 2013
    ..b>Longitudinal studies are imperative to determine the onset and progression of these abnormalities, and to identify risk factors ..
  3. Prolonged Inhibition of Pathologic Neovascularization by Catalytic Antioxidants
    JAMES FRANCIS MCGINNIS; Fiscal Year: 2013
    ..Fundoscopy, electroretinography and optical coherence tomography will be used for longitudinal studies on the same animal to evaluate neovascularization, retinal function and thickness of the outer nuclear ..
  4. Mediators of Atherosclerosis in South Asians Living in America
    Alka M Kanaya; Fiscal Year: 2013
    ..However, there are no longitudinal studies of South Asians to determine other risk factors that may explain the high prevalence of cardiovascular ..
  5. Early Disease Biomarkers of PCB-exposed Human Population
    Sisir K Dutta; Fiscal Year: 2010
    ..studies will include the current body burden, and time-dependent changes in congener profiles in longitudinal studies in newborn babies using Slovak population...
  6. The human gut microbiome, malnutrition and vaccine responses
    ANDREW LEON KAU; Fiscal Year: 2013
    ..Our lab is conducting longitudinal studies of the gut microbiomes of twins aged 1-36 months living in Malawi who are healthy, or who are concordant or ..
  7. Longitudinal Study of Lipids and APOE in the Development of AD and AD Pathology
    Michelle M Mielke; Fiscal Year: 2013
    ..b>Longitudinal studies of cognitively normal individuals with serial measures of Alzheimer's pathology in the living brain, ..
  8. Changes in Adipokines and Adiposity during Puberty and Young Adulthood
    NICOLE LENORE MIHALOPOULOS; Fiscal Year: 2013
    ..This aim includes two longitudinal studies. Study 2A is a longitudinal cohort of 642 primarily normal weight black and white children and adolescents ..
  9. Financial Risks and Ethnic/Racial Disparities in Live Kidney Donation
    TANJALA PURNELL; Fiscal Year: 2011
    ..To accomplish these aims, she will conduct cross-sectional and longitudinal studies of living kidney donation attitudes and behaviors in the United States, utilizing complex weighted survey ..
  10. A twin study of ovarian hormones and disordered eating
    Kelly L Klump; Fiscal Year: 2012
    ..The proposed set of studies follow recommendations of Becker et al. (2005) to use naturalistic, longitudinal studies across the menstrual cycle to establish associations between ovarian hormones and binge eating before ..
  11. Hepatitis C: Studies of Immunity and Pathogenesis
    Charles Rice; Fiscal Year: 2009
    ..These tools will be used to expand longitudinal studies of nAbs in acute HCV infection in the unique cohorts described in Translational Research Core A...
  12. Violence Exposure, Immune Function &HIV/AIDS Risks in African American Young Ad
    FROUGH SAADATMAND; Fiscal Year: 2013
    ..While animal studies support these associations, longitudinal studies of violence exposure and immune function in human groups, especially African Americans living in urban ..
  13. Longitudinal Studies of Autism Spectrum Disorders: 2 to 23
    Catherine Lord; Fiscal Year: 2012
    b>Longitudinal Studies of Autism Spectrum Disorder: 2 to 23 As the number of preschool children identified with autism spectrum disorder (ASD) increases each year, so too is the number of children with ASD moving into adolescence and ..
  14. Sugar-sweetened beverage taxes, beverage purchasing patterns, and weight
    Jamie F Chriqui; Fiscal Year: 2013
    ....
  15. Effects of prenatal stress exposure on childhood physical and metabolic outcomes
    Kelsey Needham Dancause; Fiscal Year: 2013
    ..These children are already participating in regular assessments for two prospective longitudinal studies of prenatal stress exposure: Project Ice Storm and the Iowa Flood Study...
  16. High Specificity HIV-1 Markers Predictive of Neuro-AIDS
    Brian Wigdahl; Fiscal Year: 2013
    ..analyses of clinical samples from a small number of patients in the pre-HAART era, rather than from longitudinal studies with sufficient patient numbers in the HAART era...
  17. Perfluoroalkyl chemicals and the risk of developing clinical and subclinical CVD
    Anoop Shankar; Fiscal Year: 2012
    ..Our study is significant because it addresses a critical barrier in the field: the lack of longitudinal studies examining the relationship between PFC exposure and the risk of clinical and subclinical measures of CVD...
  18. UNC-CH Nutrition Obesity Research Center
    Steven H Zeisel; Fiscal Year: 2013
    ..Our investigators are at the leading edge of studying the global nutrition transition, with major longitudinal studies in the United States, China and the Philippines...
  19. Longitudinal Studies of HIV-Associated Bacterial Pneumonia
    William N Rom; Fiscal Year: 2013
    ..We will freeze and store at -70 degrees plasma, serum, PBMC (RNA, DNA, protein), BAL, from involved/uninvolved lung segments, and sputum for collaborative studies with other NHLBI grantees. ..
  20. Cell cycle checkpoint defects lead to chronic inflammation in RA
    Thomas M Aune; Fiscal Year: 2013
    ..Therefore, to further test our hypothesis, we propose longitudinal studies of patients initiating methotrexate therapy to assess restoration of expression of these proteins, of cell ..
  21. Biopsychosocial approaches to healthy aging
    Terrie Vasilopoulos; Fiscal Year: 2012
    ..behavioral genetic statistics and longitudinal analysis;3) gain hands-on experience in data collection in longitudinal studies of aging and 4) examine the complex relationships among, cognitive, physical and psychosocial function ..
  22. Health and Retirement Survey for India
    David Bloom; Fiscal Year: 2009
    ..This research has the potential to inform policy in India and other Asian countries, including China, Japan, and South Korea. ..
  23. Exploring the Role of the Brain Epigenome: Cognitive Decline and Life Experiences
    David Alan Bennett; Fiscal Year: 2013
    ..The proposed study is motivated, in large part, from our work with two large, longitudinal studies of aging and dementia over the past 15 years...
  24. Trajectories and Markers of Neurodegeneration in Fragile X Premutation Carriers
    Susan M Rivera; Fiscal Year: 2013
    ..genetic, brain and neuropsychological risk factors for disease progression, however no prospective longitudinal studies have been completed that provide critical data required to identify risk or protective factors for FXTAS...
  25. Clinical Outcomes for Siblings of Children with Vesico-Ureteral Reflux
    CALEB PENNELL NELSON; Fiscal Year: 2013
    ..from a field based primarily on personal surgical experience and case series, to one based on comprehensive longitudinal studies and randomized controlled trials. I seek to contribute to this transition process...
  26. Vascular Function, Cognition, and Brain MRI in Atherosclerotic Vascular Disease
    David J Moser; Fiscal Year: 2012
    ..Despite this, there are relatively few longitudinal studies of AVD-related cognitive decline and the factors that are most predictive of this process...
  27. The Race-Specific Prevalence of Atrial Fibrillation Measured by 48-Hour Holter
    LAURA L LOEHR; Fiscal Year: 2013
    ..Institute (NHLBI) has called for advancements in AF epidemiology through increased surveillance of AF in longitudinal studies, especially among non-White ethnic groups...
  28. A qualitative description of a pilot project to improve access to care in one Den
    SARAH ELAINE RASKIN; Fiscal Year: 2011
    ..Finally, this project aims to point toward longitudinal studies of treatment narratives as a novel evaluation methodology...
  29. Erythropoietin and Neurogenesis after Neonatal Stroke
    FERNANDO FRANCISCO GONZALEZ; Fiscal Year: 2013
    ..vulnerability following hypoxic-ischemic brain injury and is an expert in stereological techniques and longitudinal studies of brain injury;and Dr...
  30. Genetic Disorder of Mucocilary Clearance
    Michael R Knowles; Fiscal Year: 2013
    ..In the next 5 years, this Consortium will complete two ongoing longitudinal studies in PCD infants, children, and adolescents, which are designed to determine the age of onset and rate of ..
  31. Social Regulation of Gene Expression
    John T Cacioppo; Fiscal Year: 2013
    ..the plausibility of a causal role for subjective social isolation in predicting transcriptional control in longitudinal studies, and (4) establishing an animal model of subjective social isolation that can provide a platform for ..
  32. Insomnia and Sleep Disordered Breathing in Seniors: A Longitudinal Outcome Study
    Nalaka S Gooneratne; Fiscal Year: 2010
    ..The presence of insomnia symptoms has been found in longitudinal studies to be associated with increased risks of depression, accidents, and falls and may lead to increased ..
  33. Self-Regulation and Sleep in Children At Risk for Autism Spectrum Disorders
    AMY J SCHWICHTENBERG; Fiscal Year: 2012
    ..Dr. Schwichtenberg also has experience on two prospective longitudinal studies of children developing at risk, making her keenly aware of the real life considerations needed to complete ..
  34. Self-Regulation and Sleep in Children At Risk for Autism Spectrum Disorders
    AMY J SCHWICHTENBERG; Fiscal Year: 2013
    ..Dr. Schwichtenberg also has experience on two prospective longitudinal studies of children developing at risk, making her keenly aware of the real life considerations needed to complete ..
  35. Lysosomal Disease Network
    Chester B Whitley; Fiscal Year: 2013
    ..In this proposal, longitudinal studies of the natural history of 11 lysosomal disease categories and 7 pilot studies of measurement of outcome and ..
  36. Multi-Disciplinary Evaluation of Chronic Pelvic Pain Syndrome
    GERALD LOUIS ANDRIOLE; Fiscal Year: 2012
    ..behavioral risk factors for development of CP/CPPS and symptom exacerbation using case-control studies and longitudinal studies. Projects 3, 4, and 5 share a common goal to evaluate the role of central nervous system abnormality in IC/..
  37. First Step: Home/School Intervention for Preschoolers with Disruptive Behaviors
    HILL M WALKER; Fiscal Year: 2013
    ..b>Longitudinal studies of the progression of antisocial behavior patterns among youth in the U.S...
  38. Early Life Nutritional Environments and Cognitive Ability in Children
    Rika Tanda; Fiscal Year: 2012
    ..The results of this research may provide insight in developing public health strategies for preventing untoward consequence of childhood obesity epidemic. ..
  39. Periodontitis and pre-clinical diabetes
    CYNTHIA MADELINE PEREZ; Fiscal Year: 2013
    ..associations between periodontal disease and type 2 diabetes, but very little evidence is available from longitudinal studies. Hence, the relationships are complex and it is unclear whether periodontal disease is a cause or ..
  40. Role of T Regulatory Cells in Preventing Human BOS
    Aric L Gregson; Fiscal Year: 2013
    ..I have become competent at FACS and analysis of such data. The complex, longitudinal studies that I propose to undertake will require statistical analysis techniques with which I am not yet familiar...
  41. The Comparative Effectiveness of Single versus Dual Chamber Cardioverter Defibril
    Pamela N Peterson; Fiscal Year: 2013
    ..The primary mentor, Frederick Masoudi, MD, MSPH, is Co-PI of the AHRQ- sponsored multicenter Longitudinal Studies of ICDs (LSICDs) which will provide the data and research infrastructure for this K08...
  42. Role of IbpA in maintaining viability of P. aeruginosa biofilm persister cells
    Michael J Franklin; Fiscal Year: 2012
    ..b>Longitudinal studies of individual patients indicate that P...
  43. Injury and Recovery in Developing Brain
    Flora M Vaccarino; Fiscal Year: 2013
    ..b>Longitudinal studies suggest recovery in both brain volume and cognitive functions by early adulthood in some children, however ..
  44. Cervical Maturity, Mucosal Immunity, and Chlamydia trachomatis infection
    Loris Y Hwang; Fiscal Year: 2012
    ..Hwang has assembled a complementary mentoring team. Her primary mentor, Anna-Barbara Moscicki MD, conducts longitudinal studies of natural HPV infection and has extensive experience in the evaluation of cervical maturity and molecular ..
  45. Measurement of health and disability trends, compression of morbidity aging study
    Somnath Chatterji; Fiscal Year: 2013
    ..applicant): The National Research Council in 2001, recognizing the need for multi-disciplinary research and longitudinal studies on aging, emphasized that cross-national studies can provide substantially more useful evidence for policy ..
  46. Chronic Conditions and Mutuality of Care in Late Life Marriage
    JOAN E MONIN; Fiscal Year: 2013
    ..Effects Study which will be used for Study 1 of the proposed research and is an expert in conducting large, longitudinal studies. Dr...
  47. Comparative Effectiveness of Biologics for Psoriasis
    Joel M Gelfand; Fiscal Year: 2010
    ..to inform patient care and will determine the willingness of psoriasis patients to participate in future longitudinal studies evaluating the comparative effectiveness of therapies for moderate to severe psoriasis...
  48. Influences of Parental Smoking on Pre-teen Reactivity to Smoking-Related Stimuli
    CATHERINE ANN FORESTELL; Fiscal Year: 2012
    ..This research will provide the foundation for future longitudinal studies to determine whether changes in cue reactivity predict smoking initiation, which will inform treatment and ..
  49. Intimate partner violence in newly married couples: The role of illicit drug use.
    Philip H Smith; Fiscal Year: 2012
    ..Multi Level Modeling will be used to test for a longitudinal relation between IDU and IPV, as well as mediation and moderation effects. ..
  50. Subjective Well-Being Over The Life Course
    STEPHEN JONATHAN MACHIN; Fiscal Year: 2013
    ..The programme will be a fully-integrated collaboration between economists, psychologists, epidemiologists and psychiatrists. ..
  51. Urinary peptide excretion and onset of puberty
    Stephen Barnes; Fiscal Year: 2009
    ..b>Longitudinal studies will allow the investigators to distinguish age-related change changes that are distinct from puberty ..
  52. Serum microRNA signature as prospective HCC biomarker in HBV patients
    Hushan Yang; Fiscal Year: 2012
    ..to our institute and are still under intensive treatment and follow-up, which will enable us to conduct longitudinal studies in the future to in-depth evaluate the effects of antiviral treatments and other factors on the risk of HCC ..
  53. Disorders of Sex Development: Platform for Basic and Translational Research
    ERIC J VILAIN; Fiscal Year: 2013
    ..of pathophysiology, impeding precise diagnostic categorization, along with the absence of prospective longitudinal studies of health and quality of life outcomes...
  54. Detection of Glaucoma Progression with Macular OCT Imaging
    Kouros Nouri-Mahdavi; Fiscal Year: 2013
    ..My long-term goal is to carry out longitudinal studies of glaucoma patients where current and upcoming imaging and functional tests can be applied and their ..
  55. Determinants of resistance in human schistosomiasis
    Daniel G Colley; Fiscal Year: 2013
    ..mansoni in Lake Victoria, and is based on 14 years of collaborative, longitudinal studies. The methodologies will primarily be analyses of the relationships between well defined clinical and ..
  56. Translational approaches to multilevel models of prenatal exposure to cigarettes
    Vanja Dukic; Fiscal Year: 2010
    ..also reveal some marked limitations of current designs for collection of biological measures of exposure in longitudinal studies, and the need for the development of better research protocols for assessing self-disclosure of smoking ..
  57. Impact of Air Pollution, Weather, and Lifestyle on Health in Older Americans
    HELEN SUH MACINTOSH; Fiscal Year: 2013
    ....
  58. Phenotyping pain in a mouse model of pancreatic cancer
    Brian M Davis; Fiscal Year: 2012
    ..a) Using Kras/p53 and control mice, we will conduct longitudinal studies of behaviors that should be affected by ongoing pain, including open field behavior, gait analysis, and ..
  59. Novel Type 2 Diabetes Mellitus Preventive Therapies
    Carine M Lenders; Fiscal Year: 2010
    ..The long term goal of this K23 Award application is to apply ideas from basic sciences and longitudinal studies in the clinical setting using a single agent or a combination of agents to prevent T2DM...
  60. Analyses of Progression to Colon Cancer in a Spectrum of Pathways
    WILLIAM FRANKLIN DOVE; Fiscal Year: 2012
    ..using our established murine models for familial colon cancer, the Min mouse and the Pirc rat, that enable longitudinal studies of polyp fate (Aim 1)...
  61. Friendships and Risk of Over-weight among Diverse-origin Adolescents
    ELIZABETH contact VAQUERA; Fiscal Year: 2010
    ....
  62. fMRI and Cognition in Adolescent Cannabis Users
    Susan F Tapert; Fiscal Year: 2010
    ..b>Longitudinal studies are essential to determine if previously observed abnormalities predate cannabis use or are caused by ..
  63. Demographic Analysis on Determinants of Healthy Longevity in China
    Yi Zeng; Fiscal Year: 2013
    ..We emphasize studying factors affecting health at old ages in the context of expanding lifespan, based on well-conducted interdisciplinary research. ..
  64. IMMUNOCHEMICAL ASSAY OF AEROALLERGENS
    Charles Reed; Fiscal Year: 1991
    b>Longitudinal studies have shown that continued exposure to the allergen after a patient has developed occupational asthma can lead to airway obstruction and hyperresponsiveness that persists for months or years after exposure ceases...
  65. METHODS FOR INCOMPLETE MENTAL HEALTH SERVICES DATA
    Thomas Belin; Fiscal Year: 2001
    ..The first study will develop a method for handling incomplete data in longitudinal studies where data may be missing on several (rather than just one) repeated measures, as well as baseline measures...
  66. EXPERIMENTAL MODELS AND CLINICAL VIROLOGY OF HEPATITIS C
    Nelson Fausto; Fiscal Year: 1999
    ..chronic hepatitis C mostly because of the long natural history of the disease and the paucity of detailed longitudinal studies. This application represents the combined efforts of investigators with expertise in clinical virology (HCV ..
  67. Prospective Risk and Protective Factors for Suicide and co-occurring Risk Behavio
    MANFRED HENDRIKUS MARIA VAN DULMEN; Fiscal Year: 2010
    ..The current project will use data from four prospective longitudinal studies (National Longitudinal Study of Adolescent Health, NICHD Study of Early Child Care and Youth Development, ..
  68. Health system based clinical trial recruitment
    Trevor J Orchard; Fiscal Year: 2011
    ..Indeed, longitudinal studies in type 2 diabetes have shown increased CVD risk in those with the Hp 2-2 genotype and retrospective ..
  69. SHARE-HRS Training Harmonization and Certification
    AXEL BOERSCH SUPAN; Fiscal Year: 2009
    ..This project will harmonize data on health policies and health outcomes in Europe with similar data in the US in order to better understand how past international health policy differences have shaped current health outcomes. ..
  70. Synthesis of HRS-SSA linked data
    LARS VILHUBER; Fiscal Year: 2007
    ..If the demonstration is successful, the methods will be extended to the entire HRS/SSA linked data in a future project. [unreadable] [unreadable] [unreadable] [unreadable]..
  71. Viral/Immune parameters of Dengue and WNV in donors: blood safety implications
    MICHAEL PAUL BUSCH; Fiscal Year: 2010
    ..Our systematic longitudinal studies of viremic donors have contributed to understanding of the natural history of WNV diseases, and elucidated ..
  72. Estimating differentials in return to work after injury from two surveys
    MICHAEL RENDALL; Fiscal Year: 2009
    ..Using the two surveys together is expected to increase the power of the statistical inference and to strengthen our understanding of the return-to- work process by including a broad range of variables and worker ages in the analysis. ..
  73. Enabling Minority Youth Research in Panel Study Income D
    ROBERT SCHOENI; Fiscal Year: 2004
    ..By extension, for analysis of subgroups within the low income sample the boost from the 730 is even more essential. ..
  74. PATHOGENESIS OF DIABETES IN CALIFORNIA MICE
    Lisa Krugner Higby; Fiscal Year: 2000
    ..We have conducted longitudinal studies that have identified populations of mice that are relatively more susceptible or resistant to the ..