intraosseous infusions

Summary

Summary: The administration of medication or fluid through a needle directly into the bone marrow. The technique is especially useful in the management of pediatric emergencies when intravenous access to the systemic circulation is difficult.

Top Publications

  1. ncbi Infant intraosseous infusion
    Scott DeBoer
    University of Chicago Hospitals, USA
    Neonatal Netw 27:25-32. 2008
  2. ncbi Intraosseous infusion
    Brian G LaRocco
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Prehosp Emerg Care 7:280-5. 2003
  3. ncbi The rebirth of adult IO
    A J Heightman
    JEMS 30:suppl 4-7. 2005
  4. ncbi Rescue access made easy
    Larry Miller
    University of Texas Health Science Center, San Antonio, TX, USA
    JEMS 30:suppl 8-18; quiz suppl 19. 2005
  5. ncbi Clinical evaluation of a novel intraosseous device for adults: prospective, 250-patient, multi-center trial
    Jack Davidoff
    Mercy Flight, 2420 Brickyard Road, Canandaigua, NY 14424, USA
    JEMS 30:suppl 20-23. 2005
  6. ncbi Osteomyelitis at the injection site of adrenalin through an intraosseous needle in a 3-month-old infant
    E Stoll
    Department of Neonatology and Paediatric ICU, University Children s Hospital, University of Vienna, Waehringer Guertel 18 20, Austria
    Resuscitation 53:315-8. 2002
  7. ncbi The utilisation of intraosseous infusion in the resuscitation of paediatric major trauma patients
    Robert Smith
    North West Deanery, 6 Broadoaks Road, Sale, Cheshire M33 7SR, UK
    Injury 36:1034-8; discussion 1039. 2005
  8. ncbi Intraosseous infusions: a review for the anesthesiologist with a focus on pediatric use
    Joseph D Tobias
    Departments of Anesthesiology, University of Missouri, Columbia, Missouri 65212, USA
    Anesth Analg 110:391-401. 2010
  9. ncbi Ready, aim, fire! New IO device simplifies vascular access in severe cases
    Jeff Lindsey
    Estero Fla Fire Rescue, USA
    JEMS 28:97-8. 2003
  10. pmc Clinical review: vascular access for fluid infusion in children
    Nikolaus A Haas
    Paediatric Intensive Care Unit, The Prince Charles Hospital, Brisbane, Australia
    Crit Care 8:478-84. 2004

Detail Information

Publications122 found, 100 shown here

  1. ncbi Infant intraosseous infusion
    Scott DeBoer
    University of Chicago Hospitals, USA
    Neonatal Netw 27:25-32. 2008
    ..This article examines IO infusion devices and placement sites and addresses assessment and care of the infant receiving IO fluids and medications...
  2. ncbi Intraosseous infusion
    Brian G LaRocco
    Department of Emergency Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Prehosp Emerg Care 7:280-5. 2003
    ..The authors review the history, anatomy, technique, and clinical application of IOI. They also highlight the use of IOI in the prehospital setting...
  3. ncbi The rebirth of adult IO
    A J Heightman
    JEMS 30:suppl 4-7. 2005
  4. ncbi Rescue access made easy
    Larry Miller
    University of Texas Health Science Center, San Antonio, TX, USA
    JEMS 30:suppl 8-18; quiz suppl 19. 2005
  5. ncbi Clinical evaluation of a novel intraosseous device for adults: prospective, 250-patient, multi-center trial
    Jack Davidoff
    Mercy Flight, 2420 Brickyard Road, Canandaigua, NY 14424, USA
    JEMS 30:suppl 20-23. 2005
  6. ncbi Osteomyelitis at the injection site of adrenalin through an intraosseous needle in a 3-month-old infant
    E Stoll
    Department of Neonatology and Paediatric ICU, University Children s Hospital, University of Vienna, Waehringer Guertel 18 20, Austria
    Resuscitation 53:315-8. 2002
    ....
  7. ncbi The utilisation of intraosseous infusion in the resuscitation of paediatric major trauma patients
    Robert Smith
    North West Deanery, 6 Broadoaks Road, Sale, Cheshire M33 7SR, UK
    Injury 36:1034-8; discussion 1039. 2005
    ..We recommend that intraosseous line use should be a skill available to everybody involved in paediatric trauma resuscitation, particularly those who may not have refined paediatric intravenous cannulation skills...
  8. ncbi Intraosseous infusions: a review for the anesthesiologist with a focus on pediatric use
    Joseph D Tobias
    Departments of Anesthesiology, University of Missouri, Columbia, Missouri 65212, USA
    Anesth Analg 110:391-401. 2010
    ..We present the history of IO infusions, review the anatomy of the bone marrow space, discuss the potential role of IO infusions in the perioperative period, and analyze its adverse effect profile...
  9. ncbi Ready, aim, fire! New IO device simplifies vascular access in severe cases
    Jeff Lindsey
    Estero Fla Fire Rescue, USA
    JEMS 28:97-8. 2003
  10. pmc Clinical review: vascular access for fluid infusion in children
    Nikolaus A Haas
    Paediatric Intensive Care Unit, The Prince Charles Hospital, Brisbane, Australia
    Crit Care 8:478-84. 2004
    ..Additionally, in emergency situations the intraosseous access has almost completely replaced saphenous cutdown procedures in children and has decreased the need for immediate central venous access...
  11. pmc Use of a butterfly as an intraosseous needle in an oedematous preterm infant
    W Lake
    Neonatal Medical Unit, St Mary s Hospital, Whitworth Park, Manchester, M13 0JH, UK
    Arch Dis Child Fetal Neonatal Ed 88:F409. 2003
  12. ncbi Medullary plasma pharmacokinetics of vancomycin after intravenous and intraosseous perfusion of the proximal phalanx in horses
    Luis Rubio-Martinez
    Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Universidad Complutense de Madrid, Spain
    Vet Surg 34:618-24. 2005
    ..To study the pharmacokinetics of vancomycin in plasma obtained from the medullary sinusoids of the proximal phalanx (P1) after intravenous (IV) and intraosseous (IO) regional limb perfusion (RLP)...
  13. ncbi Pediatric trauma resuscitation: initial fluid management
    Lynn Schweer
    Cincinnati Children s Hospital, ML 3019, Trauma Service, 3333 Burnet Avenue, Cincinnati, OH 45229, USA
    J Infus Nurs 31:104-11. 2008
    ..However, specific issues around timing and type of fluid administration, once thought to be straightforward, have triggered increasing investigation of current beliefs...
  14. ncbi Intra-osseous access (EZ-IO) for resuscitation: UK military combat experience
    B R Cooper
    212 Field Hospital RAMC V
    J R Army Med Corps 153:314-6. 2007
    ..No complication of infection was noted, but pain was observed in responsive patients with the pain of infusion exceeding that of the underlying injuries in 3 cases...
  15. ncbi Does intraosseous equal intravenous? A pharmacokinetic study
    Daniel D Von Hoff
    Translational Genomics Research Institute and Arizona Cancer Center, University of Arizona, Phoenix, AZ 85721, USA
    Am J Emerg Med 26:31-8. 2008
    ..The objective of the study was to compare the pharmacokinetics of intraosseous vs intravenous administration of morphine sulfate in adults...
  16. ncbi A tracer study with systemically and locally administered dinitrophenylated osteopontin
    Antonio Nanci
    Laboratory for the Study of Calcified Tissues and Biomaterials, Faculty of Dentistry, Universite de Montreal, PO Box 6128, Station Centre Ville, Montreal, QC, Canada H3C 3J7
    J Histochem Cytochem 52:1591-600. 2004
    ..These results show that circulating OPN can be incorporated into specific compartments of forming bone and suggest that such molecules may play a more important role than previously suspected...
  17. ncbi Intraosseous hypertonic saline solution for resuscitation of uncontrolled, exsanguinating liver injury in young Swine
    R M Carrera
    Pediatric Surgery Division, Santa Casa São Paulo, Faculty of Medical Sciences, Sao Paulo, Brazil
    Eur Surg Res 36:282-92. 2004
    ..It was concluded that the hypertonic saline solution in this experimental model did not promote hemodynamic improvement and there were no differences between the two sites of fluid resuscitation regarding intra-abdominal blood loss...
  18. ncbi [Intraosseous access in adults--an alternative if conventional vascular access is difficult?]
    Dan Lou Isbye
    H S Rigshospitalet, og HovedOrtoCentret, Anaestesi og Operationsklinikken, København Ø
    Ugeskr Laeger 168:2793-7. 2006
    ..Infusion rates have been achieved that in part make fluid resuscitation possible. Its uses are many and the contraindications few; complications are rare when simple guidelines are followed...
  19. ncbi [Intraosseous infusion for adults]
    B A Leidel
    Chirurgische Klinik und Poliklinik, Klinikum der Universitat Munchen, Innenstadt, Munchen, Germany
    Chirurg 79:315-26. 2008
    ..Rapid IO access is now possible in all age groups, and the 2005 AHA Guidelines favor it over drug administration via the endotracheal tube...
  20. ncbi Venous access in the critically ill child: when the peripheral intravenous fails!
    Allan de Caen
    Division of Pediatric Critical Care, Stollery Children s Hospital, Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada
    Pediatr Emerg Care 23:422-4; quiz 425-6. 2007
    ....
  21. ncbi Sternal intraosseous infusions: emergency vascular access in adults
    Mary Jo Koschel
    AirLife, Greeley, CO, USA
    Am J Nurs 105:66-8. 2005
  22. ncbi [Role of intraosseous access in emergency]
    Luc Aniset
    Klinik fur Anasthesiologie und Operative Intensivmedizin, Universitatsklinikum Mannheim, Germany
    Anasthesiol Intensivmed Notfallmed Schmerzther 42:494-9. 2007
    ..Rescuers should learn safe techniques of establishing an intraosseous access. Equipment of rescue vehicles with adequate devices for children and adults should be considered standard...
  23. ncbi Intraosseous vascular access. Devices, sites & rationale for I0 use
    Marvin A Wayne
    EMS in Bellingham Whatcom County, Wash, USA
    JEMS 32:S23-5. 2007
  24. ncbi Randomized controlled trial of an instructional DVD for clinical skills teaching
    Joon C Lee
    Department of Emergency Medicine, Lyell McEwin Health Service, Elizabethvale, South Australia, Australia
    Emerg Med Australas 19:241-5. 2007
    ..The clinical skill selected for the study was that of paediatric intraosseous (IO) needle insertion...
  25. pmc Best evidence topic reports. Screw tipped needles for intraosseous access
    Simon Carley
    Department of Emergency Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK
    Emerg Med J 21:336-7. 2004
    ..The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of this best paper are tabulated. A clinical bottom line is stated...
  26. ncbi Epidural needle and intraosseous access
    Oluyombo A Awojobi
    Trop Doct 33:59. 2003
  27. ncbi Hypertonic saline: intraosseous infusion causes myonecrosis in a dehydrated swine model of uncontrolled hemorrhagic shock
    Hasan B Alam
    Department of Surgery, Uniformed Services University of the Health Sciences, Bethesda, Maryland 20814, USA
    J Trauma 52:18-25. 2002
    ..5% hypertonic saline (HTS) for combat casualties in shock. We tested the safety and efficacy of this recommendation in a long-term survival model of uncontrolled hemorrhagic shock using dehydrated swine...
  28. pmc Continuous infusion of insulin-like growth factor-I into the epiphysis of the tibia
    Aziz Abbaspour
    Department of Orthopedics, Institute of Health Biosciences, The University of Tokushima Graduate School, 3 18 15 Kuramoto, Tokushima 770 8503, Japan
    Int Orthop 32:395-402. 2008
    ..These results suggest that the method reported here is a valid one for delivering cytokines or growth factors to the selected GP and for controlling the growth and differentiation of physeal chondrocytes...
  29. ncbi [Tibial osteomyelitis following intraosseous infusion: a case report]
    Ali Dogan
    Department of Orthopedics and Traumatology Ortopedi ve Travmatoloji Anabilim Dali, Medicine Faculty of Yüzüncü Yıl University, Van, Turkey
    Acta Orthop Traumatol Turc 38:357-60. 2004
    ..Cultures from the surgical site yielded Candida albicans, upon which fluconazole (8 mg/kg) treatment was administered for four weeks. A complete clinical and radiographic improvement was observed at the end of a 12-month follow-up...
  30. pmc Cerebral arterial air embolism in a child after intraosseous infusion
    R R van Rijn
    Department of Radiology, Academic Medical Centre Emma Children s Hospital, Amsterdam, The Netherlands
    Emerg Radiol 15:259-62. 2008
    ..There has been one reported case of CAAE after the use of an intraosseous infusion (IO) system. We report on a case of CAAE after tibial IO infusion in a 7-month-old girl during resuscitation...
  31. ncbi Comparison of epinephrine with vasopressin on bone marrow blood flow in an animal model of hypovolemic shock and subsequent cardiac arrest
    W G Voelckel
    Cardiac Arrhythmia Center, Cardiovascular Division, Department of Medicine at the University of Minnesota, Minneapolis, MN, USA
    Crit Care Med 29:1587-92. 2001
    ..These findings emphasize the need for pressurized intraosseous infusion techniques, because bone marrow blood flow may not be predictable during hemorrhagic shock and drug therapy...
  32. ncbi Comparison of intraosseous or intravenous infusion for delivery of amikacin sulfate to the tibiotarsal joint of horses
    Brad C Scheuch
    Veterinary Medical Teaching Hospital, School of Veterinary Medicine, University of California, Davis 95616, USA
    Am J Vet Res 63:374-80. 2002
    ..To establish the route of infusion (IV or intraosseous) that results in the highest concentration of amikacin in the synovial fluid of the tibiotarsal joint and determine the duration of peak concentrations...
  33. ncbi Intraosseous access for administration of medications in neonates
    William A Engle
    Department of Pediatrics, James Whitcomb Riley Hospital, Indiana University School of Medicine, Indianapolis, IN 46202 5119, USA
    Clin Perinatol 33:161-8, ix. 2006
    ....
  34. ncbi Antimicrobial regional limb perfusion in horses
    Luis M Rubio-Martínez
    Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON N1G 2W1, Canada
    J Am Vet Med Assoc 228:706-12, 655. 2006
    ..The technique provides high antimicrobial concentrations in the region of interest and greatly contributes to the elimination of infection...
  35. doi Intra-arterial access in pediatric patients
    Rajesh Mahajan
    Paediatr Anaesth 18:670-1. 2008
  36. ncbi Powered intraosseous access in the prehospital setting: MCHD EMS puts the EZ-IO to the test
    Lee Gillum
    JEMS 30:suppl 24-5. 2005
  37. ncbi Intraosseous gentamicin perfusion of the distal metacarpus in standing horses
    Shawn Mattson
    Department of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, Canada
    Vet Surg 33:180-6. 2004
    ..To report tissue gentamicin concentrations after intraosseous (IO) perfusion in standing horses...
  38. ncbi A randomized comparison of cardiocerebral and cardiopulmonary resuscitation using a swine model of prolonged ventricular fibrillation
    Timothy J Mader
    The Department of Emergency Medicine, Baystate Medical Center Tufts University School of Medicine, 759 Chestnut Street, Springfield, MA 01199, USA
    Resuscitation 81:596-602. 2010
    ....
  39. ncbi Paramedic evaluation of adult Intraosseous Infusion System
    Judy Findlay
    Pyng Medical Corp, Vancouver, British Columbia, Canada
    Prehosp Disaster Med 21:329-34. 2006
    ..During the development of the device, key objectives included safety, speed of insertion, and ease of use with minimal training. This study evaluated these characteristics...
  40. ncbi Comparison of two mechanical intraosseous infusion devices: a pilot, randomized crossover trial
    Itai Shavit
    Emergency Department, Meyer Children s Hospital, Rambam Health Care Campus, Haifa, Israel
    Resuscitation 80:1029-33. 2009
    ..The objective of this pilot study was to compare the success rates for insertion and the ease-of-use of the two devices...
  41. ncbi Intraosseous infusion into the skull: potential application for the management of hydrocephalus
    Jeffrey A Pugh
    Department of Surgery, University of Alberta, Edmonton, Alberta, Canada
    J Neurosurg 106:120-5. 2007
    ..The focus of this work has been to recreate more normal CSF absorption into the dural venous sinuses without having to directly access the superior sagittal sinus (SSS)...
  42. ncbi [Efficacy of intraosseous infusions of 0.03% sodium hypochlorite solution in combined therapy of patients with chronic traumatic mandibular osteomyelitis]
    Iu V Efimov
    Stomatologiia (Mosk) 82:32-3. 2003
  43. ncbi IO versus IV access while wearing personal protective equipment in a HazMat scenario
    Joe Suyama
    Department of Emergency Medicine, Emergency Responder Human Performance Lab, University of Pittsburgh PA 15213, USA
    Prehosp Emerg Care 11:467-72. 2007
    ..Determine the time difference obtaining intraosseous (IO) versus intravenous (IV) access while wearing personal protective equipment (PPE) in simulated HazMat scenarios...
  44. ncbi Nailing down IO insertion. The whys, whens, wheres and hows of delivering fluids and medications the intraosseous way
    Marc A Minkler
    Portland ME Fire Department, USA
    EMS Mag 36:38, 40, 42. 2007
  45. ncbi Local infusion of FGF-2 enhances bone ingrowth in rabbit chambers in the presence of polyethylene particles
    Stuart B Goodman
    Division of Orthopaedic Surgery, R144, Stanford University Medical Center, 300 Pasteur Drive, Stanford, California 94305 5341, USA
    J Biomed Mater Res A 65:454-61. 2003
    ..g., in treating early osteolytic lesions), and facilitating osseointegration of revision total joint replacements in situations where the bone bed is suboptimal and residual particles and granulomatous tissue are present...
  46. ncbi Pilot trial of interleukin-2 with granulocyte colony-stimulating factor for the mobilization of progenitor cells in advanced breast cancer patients undergoing high-dose chemotherapy: expansion of immune effectors within the stem-cell graft and post-stem-c
    J A Sosman
    Section of Hematology Oncology, University of Illinois at Chicago College of Medicine, Chicago 60612, USA
    J Clin Oncol 19:634-44. 2001
    ....
  47. pmc Discovery of the intraosseous route for fluid administration
    B A Foex
    Department of Accident and Emergency Medicine, Royal Bolton Hospital
    J Accid Emerg Med 17:136-7. 2000
    ..Just before the outbreak of the second world war a chance discovery resulted in the development of intraosseous infusions of fluid and drugs. From its discovery it was used in adults and children...
  48. ncbi The administration of drugs during resuscitation
    Phil Jevon
    Manor Hospital, Walsall
    Nurs Times 103:26-7. 2007
    ..There are a few drugs that are indicated during the initial management of a cardiac arrest. They can be considered once defibrillation has been performed (if indicated) and CPR has started...
  49. pmc Current use of intraosseous infusion in Danish emergency departments: a cross-sectional study
    Rune Molin
    Department of Emergency Medicine, Holbaek Sygehus, Holbaek, Denmark
    Scand J Trauma Resusc Emerg Med 18:37. 2010
    ..Intraosseous infusion (IOI) is recommended when intravenous access cannot be readily established in both pediatric and adult resuscitation. We evaluated the current use of IOI in Danish emergency departments (EDs)...
  50. ncbi Evaluation of the bone injection gun as a method for intraosseous cannula placement for fluid therapy in adult dogs
    Dennis Olsen
    Department of Clinical Sciences, College of Veterinary Medicine, Kansas State University, Manhattan 66506, USA
    Vet Surg 31:533-40. 2002
    ..To evaluate the Bone Injection Gun (BIG) for placement of intraosseous cannulas through impact penetration and compare it with a standard Jamshidi bone marrow needle (JBMN) and to compare fluid delivery dynamics through each device...
  51. ncbi Intraosseous access in the setting of pediatric critical care transport
    Brad A Fiorito
    Division of Pediatric Critical Care, Loma Linda University School of Medicine, Loma Linda, CA, USA
    Pediatr Crit Care Med 6:50-3. 2005
    ..To demonstrate safety and efficacy of intraosseous needle placement among health care provider groups in the setting of pediatric critical care transport...
  52. ncbi Long-term effects on tibial growth after intraosseous infusion: a prospective, radiographic analysis
    I Claudet
    Department of Pediatric Emergency, Children Hospital, Toulouse, France
    Pediatr Emerg Care 19:397-401. 2003
    ..Evaluate, by radiographic analysis, tibial growth after an intraosseous infusion (IOI) in a pediatric population...
  53. ncbi New bone formation by allogeneic mesenchymal stem cell transplantation in a patient with perinatal hypophosphatasia
    Mika Tadokoro
    Research Institute for Cell Engineering, National Institute of Advanced Industrial Science and Technology, Hyogo, Japan
    J Pediatr 154:924-30. 2009
    ..We demonstrated the importance of allogeneic MSC transplantation for hypophosphatasia and the constructs as an alternative to bone fragments that provided further osteogenic capability in the patient...
  54. ncbi Carboplatin pharmacokinetics following a single-dose infusion in sulphur-crested cockatoos (Cacatua galerita)
    L J Filippich
    The University of Queensland, Queensland, 4072
    Aust Vet J 82:366-9. 2004
    ..To determine the pharmacokinetics of carboplatin in sulphur-crested cockatoos, so that its use in clinical studies in birds can be considered...
  55. ncbi Tibial fracture as a complication of intraosseous infusion during pediatric resuscitation
    Douglas M G Bowley
    Johannesburg Hospital and the University of the Witwatersrand Medical School Johannesburg, Republic of South Africa
    J Trauma 55:786-7. 2003
  56. ncbi Ultrasonographic confirmation of intraosseous needle placement in an adult unembalmed cadaver model
    Michael B Stone
    Division of Emergency Medicine, University of Medicine and Dentistry of New Jersey, Newark, NJ 07103, USA
    Ann Emerg Med 49:515-9. 2007
    ..This study's aim is to determine the value of bedside ultrasonography as a means of confirming intraosseous needle placement by visualizing the flow of crystalloid within the intraosseous space...
  57. ncbi Compartment syndrome following intraosseous infusion
    Todd C Moen
    Department of Orthopedic Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL 60614 3363, USA
    Orthopedics 31:815. 2008
    ..This case highlights the fundamental principles regarding the use of intraosseous infusion and the diagnosis and management of compartment syndrome in critically ill patients...
  58. pmc Best evidence topic report. Bone injection gun placement of intraosseous needles
    Andrew Curran
    Emerg Med J 22:366. 2005
    ..The author, date and country of publication, patient group studied, study type, relevant outcomes, results and study weaknesses of these best papers are tabulated. A clinical bottom line is stated...
  59. doi Intraosseous needles: they're not just for kids anymore
    Denise M Langley
    Oregon Health Science University, Portland, Ore, USA
    J Emerg Nurs 34:318-9. 2008
  60. ncbi Comparison of intravenous and intraosseous access by pre-hospital medical emergency personnel with and without CBRN protective equipment
    Lionel Lamhaut
    SAMU de Paris, Département d Anesthésie Réanimation SAMU, Hopital Necker Enfants Malades, 149 rue de Sevres, 75730 Paris Cedex 15, Université Paris Descartes Paris V, France
    Resuscitation 81:65-8. 2010
    ....
  61. ncbi Comparison of two indirect techniques for local delivery of a high dose of an antimicrobial in the distal portion of forelimbs of horses
    Jason A Errico
    Department of Large Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL 32610, USA
    Am J Vet Res 69:334-42. 2008
    ....
  62. ncbi Intraosseous embolotherapy of central arteriovenous malformations in the jaw: long-term experience with 8 cases
    Denggao Liu
    Department of Oral Radiology, Peking University, School and Hospital of Stomatology, Beijing, China
    J Oral Maxillofac Surg 67:2380-7. 2009
    ..To investigate the long-term effects of direct intraosseous histoacryl embolotherapy on central arteriovenous malformations (AVMs) of the jaw...
  63. ncbi Advanced techniques and armamentarium for dental local anesthesia
    Taylor M Clark
    Dental Anesthesiology Residency Program, School of Dentistry, University of California, Los Angeles, Los Angeles, CA 90095 1668, USA
    Dent Clin North Am 54:757-68. 2010
    ..Supplementary IO anesthesia is particularly suited for providing effective pain control of teeth diagnosed with irreversible pulpitis...
  64. ncbi Insulin infusion via an intraosseous needle in diabetic ketoacidosis
    K A Alawi
    Critical Care Unit, Department of Paediatrics, Children s Hospital of Western Ontario, University of Western Ontario and Children s Health Research Institute, London, Ontario, Canada
    Anaesth Intensive Care 36:110-2. 2008
    ..We suggest that the potential role of intraosseous access, when intravenous access can not be obtained, should be considered when management guidelines for paediatric diabetic ketoacidosis with dehydration are reviewed...
  65. doi Standard 63: intraosseous access devices
    Lisa A Gorski
    J Infus Nurs 31:146-7. 2008
  66. ncbi Semi-elective intraosseous infusion after failed intravenous access in pediatric anesthesia
    Diego Neuhaus
    Department of Anesthesia, University Children s Hospital, Zurich, Switzerland
    Paediatr Anaesth 20:168-71. 2010
    ..Intraosseous (IO) infusion is a well-established intervention to obtain vascular access in pediatric emergency medicine but is rarely used in routine pediatric anesthesia...
  67. ncbi Use of a battery-operated needle driver for intraosseous access by novice users: skill acquisition with cadavers
    Richard M Levitan
    Albert Einstein Medical Center, Department of Emergency Medicine, 5501 Old York Road, Philadelphia, PA 19141, USA
    Ann Emerg Med 54:692-4. 2009
    ..We determine skill acquisition and performance by using a battery-operated, intraosseous needle driver in cadavers...
  68. ncbi The use of intraosseous infusions in the operating room
    Gayatri Joseph
    University of Missouri School of Medicine, Columbia, MO, USA
    J Clin Anesth 20:469-73. 2008
    ..When intravenous access could not be achieved, an IO needle was placed and IO access was used during the surgical procedure. The role of the IO route in the perioperative period is discussed and its adverse effect profile is reviewed...
  69. ncbi Intraosseous infusion: a review of methods and novel devices
    Stephen M Blumberg
    Division of Emergency Medicine, Department of Pediatrics, Jacobi Medical Center, Albert Einstein College of Medicine, Bronx, NY 10461, USA
    Pediatr Emerg Care 24:50-6; quiz 57-8. 2008
    ..This is a review article of intraosseous infusion methods and devices...
  70. ncbi The use of intraosseous anesthesia among endodontists: results of a questionnaire
    Chad Bangerter
    US Army Endodontic Residency Program, Fort Bragg, North Carolina, USA
    J Endod 35:15-8. 2009
    ....
  71. ncbi COMP-Angiopoietin-1 ameliorates surgery-induced ischemic necrosis of the femoral head in rats
    Byung Hyun Park
    Department of Biochemistry, Medical School and Research Institute of Clinical Medicine, Chonbuk National University, Jeonju, Jeonbuk, Republic of Korea
    Bone 44:886-92. 2009
    ..Moreover, the process of bone healing is intimately associated with angiogenesis. We considered that COMP-Ang1 (an angiogenic factor) might preserve femoral head structure and facilitate bone repair...
  72. ncbi Osteomyelitis and osteonecrosis after intraosseous perfusion with gentamicin
    Russell A Parker
    Department of Veterinary Clinical Studies, Easter Bush Veterinary Centre, University of Edinburgh, Large Animal Hospital, Midlothian EH25 9RG, UK
    Vet Surg 39:644-8. 2010
    ..To describe and discuss previously unreported complications associated with intraosseous perfusion with gentamicin in horses...
  73. ncbi Intraosseous catheter placement in small mammals
    Ashley Zehnder
    University of California Davis, Veterinary Medical Teaching Hospital, Davis, CA, USA
    Lab Anim (NY) 37:351-2. 2008
    ..This column describes the necessary equipment, procedure and potential complications of intraosseous catheterization...
  74. ncbi Effects of single and cyclical local injections of basic fibroblast growth factor on cancellous bone defects in rabbits
    Keiji Kamo
    Department of Orthopedic Surgery, Akita University Graduate School of Medicine, 1 1 1 Hondo, Akita 010 8543, Japan
    J Orthop Sci 14:811-9. 2009
    ..However, little is known about the effects of cyclical local injection of bFGF. We evaluated the effects of single and cyclical local injection of bFGF at a cancellous bone defect in the femoral condyle in rabbits...
  75. ncbi Proximal humerus intraosseous infusion: a preferred emergency venous access
    James H Paxton
    Department of Emergency Medicine, Henry Ford Hospital, Detroit, Michigan 48202, USA
    J Trauma 67:606-11. 2009
    ....
  76. ncbi Comparison of two intraosseous access devices in adult patients under resuscitation in the emergency department: A prospective, randomized study
    Bernd A Leidel
    Department of Emergency Medicine, Charite Universitatsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany
    Resuscitation 81:994-9. 2010
    ..Most available data derive from children, animal models, cadaver studies or the prehospital setting. Therefore we compared two different IO access devices in adults under resuscitation in the hospital setting...
  77. ncbi Intraosseous devices: a randomized controlled trial comparing three intraosseous devices
    Klaas A Hartholt
    Department of Surgery Traumatology, Erasmus Medical Center, Rotterdam, The Netherlands
    Prehosp Emerg Care 14:6-13. 2010
    ..In the last decade, the IO method gained renewed interest. New devices have been developed, such as the Bone Injection Gun (BIG) 15G/18G and the First Access for Shock and Trauma 1 (FAST1)...
  78. ncbi [Preclinical use of intraosseous access (IO) in adults: literature review and case reports]
    Michael Toursarkissian
    Department of Anesthesiology and Intensive Care, Charite Universitaetsmedizin Berlin, Campus Charité Mitte and Campus Virchow Klinikum, Berlin, Germany
    Anasthesiol Intensivmed Notfallmed Schmerzther 44:22-7. 2009
    ..The following article illustrates the basic literature and two case reports, and is designed to inspire trust in a method, which can provide a useful alternative to peripheral venous access for the emergency physician...
  79. doi A new route to the stem-cell niche
    John E Wagner
    Lancet Oncol 9:812-4. 2008
  80. ncbi Intraosseous approach to vascular access in adult resuscitation
    Rob Fenwick
    Princess Royal Hospital, Telford
    Emerg Nurse 18:22-5. 2010
    ..This article focuses on the increased use of intraosseous (IO) access in adult resuscitation. The IO route is described and the indications and contraindications considered. Common insertion sites and devices of IO access are discussed...
  81. ncbi The use of a powered device for intraosseous drug and fluid administration in a national EMS: a 4-year experience
    Dagan Schwartz
    MDA Medical Division, Tel Aviv, Israel
    J Trauma 64:650-4; discussion 654-5. 2008
    ....
  82. ncbi Powered intraosseous insertion provides safe and effective vascular access for pediatric emergency patients
    Mark A Horton
    Wolfson Children s Hospital, Jacksonville, FL, USA
    Pediatr Emerg Care 24:347-50. 2008
    ....
  83. doi IO objectives
    Alan Moloff
    JEMS 33:22; author reply 22. 2008
  84. ncbi Stories behind the numbers. I0 experiences in providers' own words
    James S Potyka
    San Antonio AirLife, Texas, USA
    JEMS 32:S30-1. 2007
  85. ncbi Osteoreflectory treatment of alcohol abstinence syndrome and craving for alcohol in patients with alcoholism
    G Yankovskis
    Latvian University Institute for Experimental and Clinical Medicine
    Acupunct Electrother Res 25:9-16. 2000
    ..Primarily because of these two cited factors, the patient can be freed of the craving for alcohol for several years, and he or she also does not suffer from depression...
  86. ncbi Intraosseous infusion: not just for kids anymore
    Scott DeBoer
    University of Chicago Aeromedical Network, USA
    Emerg Med Serv 34:54, 56-63; quiz 119. 2005
  87. ncbi Intraosseous infusions via the calcaneus
    Michael Clem
    Resuscitation 62:107-12. 2004
    To demonstrate that intraosseous infusions via the calcaneus could deliver fluids to systemic veins and that intraosseous infusions do not require bones with medullary cavities...
  88. ncbi Intraosseous vascular access in the treatment of chemical warfare casualties assessed by advanced simulation: proposed alteration of treatment protocol
    Amir Vardi
    The Israel Center for Medical Simulation, Sheba Medical Center, Tel Hashomer, Israel 52621
    Anesth Analg 98:1753-8, table of contents. 2004
    ..8%. Personnel satisfaction with the intraosseous device was unanimous and high. New-generation intraosseous infusions have great potential value in the early treatment stages of chemical warfare casualties.
  89. ncbi Which IO model best simulates the real thing?
    Floyd S Ota
    Department of Pediatrics, University of Hawaii John A Burns School of Medicine, USA
    Pediatr Emerg Care 19:393-6. 2003
    ..To determine which model best simulates the actual IO procedure in children...
  90. ncbi Intraosseous emergency access by physicians wearing full protective gear
    Ron Ben-Abraham
    Department of Anesthesiology and Critical Care Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel
    Acad Emerg Med 10:1407-10. 2003
    ..To assess prospectively and randomly the feasibility, speed, and success rate of establishing an intraosseous access using the Bone Injection Gun (BIG) while wearing antichemical outfits...
  91. ncbi Act FAST with intraosseous infusion
    Michael W Day
    Nortwest MedStar and Sacred Heart Medical Center, Spokane, WA, USA
    Nursing 33:50-2. 2003
  92. ncbi Leg amputation after intraosseous infusion in a 7-month-old infant: a case report
    Franck Launay
    Service of Chirurgie Orthopédique, Hôspital d Enfants de la Timone, Marseille, France
    J Trauma 55:788-90. 2003
  93. ncbi [Intra-osseous fluid resuscitation using Mallarmé needle in severely dehydrated infant]
    X Nicolas
    Arch Pediatr 10:733-4. 2003
  94. ncbi Bone gun question
    Lucy DeTamble
    JEMS 28:21; discussion 21. 2003
  95. ncbi Successful intraosseous infusion in the critically ill patient does not require a medullary cavity
    Gerard McCarthy
    Department of Emergency Medicine, Cork University Hospital, Wilton, Cork, Ireland
    Resuscitation 56:183-6. 2003
    ..To demonstrate that successful intraosseous infusion in critically ill patients does not require bone that contains a medullary cavity...
  96. ncbi Prevention of senile osteoporosis in SAMP6 mice by intrabone marrow injection of allogeneic bone marrow cells
    Naoya Ichioka
    First Department of Pathology, Kansai Medical University, Moriguchi City, Osaka, Japan
    Stem Cells 20:542-51. 2002
    ....
  97. ncbi A new animal model of femoral head necrosis induced by intraosseous injection of ethanol
    J Manggold
    Department of Orthopaedics, University of Heidelberg, Germany
    Lab Anim 36:173-80. 2002
    ..Due to its efficacy and its similarity to the early stages of ONFH in humans, this model may be suitable to evaluate new therapeutic techniques in the treatment of ONFH...
  98. pmc Comparison of 2 techniques for regional antibiotic delivery to the equine forelimb: intraosseous perfusion vs. intravenous perfusion
    T D Butt
    Department of Large Animal Clinical Sciences, Western College of Veterinary Medicine, University of Saskatchewan, 52 Campus Drive, Saskatoon, Saskatchewan S7N 5B4
    Can Vet J 42:617-22. 2001
    ..Each technique produced mean peak concentrations ranging from 5 to 50 times that of recommended peak serum concentrations for therapeutic efficacy...
  99. ncbi Assessment of intracranial pressure volume relationships in childhood: the lumbar infusion test versus intracranial pressure monitoring
    P K Eide
    Department of Neurosurgery, The National Hospital, University of Oslo, Norway
    Childs Nerv Syst 17:382-90. 2001
    ....
  100. ncbi Transplantation of a whole ear allograft by immunological induction of donor-specific tolerance by bone marrow transplantation: an experimental study in rabbits
    Yi Biao Wang
    Department of Plastic and Reconstructive Surgery, Kansai Medical University, Osaka, Japan
    Scand J Plast Reconstr Surg Hand Surg 39:73-6. 2005
    ..These results suggest that a single intraosseous injection of donor bone marrow cells is sufficient for induction of donor-specific tolerance in rabbits and that immunosuppressive agents may not be needed...
  101. ncbi Feasibility of sternal intraosseous access by emergency medical technician students
    David D Miller
    University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15213, USA
    Prehosp Emerg Care 9:73-8. 2005
    ..This study was conducted to examine the feasibility of training EMT-B students to correctly place a commercial sternal IO infusion device (FAST-1)...

Research Grants2

  1. Infusion of Particles at Implant interfeces
    Stuart Goodman; Fiscal Year: 2006
    ..abstract_text> ..
  2. Osteolysis and Implant Wear: Biological, Biomedical Engineering, and Surgical Pri
    Stuart Goodman; Fiscal Year: 2007
    ..unreadable] [unreadable] [unreadable] [unreadable]..